[ { "uniprot_canonical_ac": "F1N5P3-1", "uniprot_ac": "F1N5P3", "uniprot_id": "F1N5P3_BOVIN", "mass": { "chemical_mass": 55634.0, "monoisotopic_mass": 55634.0 }, "refseq": { "ac": "XP_010819233", "name": "tRNA pseudouridine(38/39) synthase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819233" }, "gene_names": [ { "name": "PUS3", "type": "recommended", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ] }, { "name": "PUS3", "type": "synonym", "evidence": [ { "id": "XP_010819233", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819233" } ] } ], "protein_names": [ { "name": "tRNA pseudouridine(38/39) synthase", "type": "recommended", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3/entry#names_and_taxonomy" } ] }, { "name": "5.4.99.45", "type": "synonym", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3/entry#names_and_taxonomy" } ] }, { "name": "tRNA pseudouridine synthase 3", "type": "synonym", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3/entry#names_and_taxonomy" } ] }, { "name": "tRNA pseudouridine(38/39) synthase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010819233", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819233" } ] }, { "name": "tRNA pseudouridylate synthase 3", "type": "synonym", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3/entry#names_and_taxonomy" } ] }, { "name": "tRNA-uridine isomerase 3", "type": "synonym", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PUS3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3", "locus": { "chromosome": "29", "start_pos": 29247986, "end_pos": 29250458, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014339", "url": "https://www.ensembl.org/id/ENSBTAG00000014339" } ] } } ], "crossref": [ { "id": "F1N5P3", "url": "https://alphafold.ebi.ac.uk/entry/F1N5P3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014339", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014339", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "515824", "url": "https://www.ncbi.nlm.nih.gov/gene/515824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YFGWEYN", "url": "https://omabrowser.org/oma/group/YFGWEYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N5P3", "url": "https://www.orthodb.org/?gene=F1N5P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11142:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11142:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010819233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819233", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "42564", "url": "https://www.rhea-db.org/rhea/42564", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5P3-1", "url": "https://www.uniprot.org/uniprotkb/F1N5P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAENDVDRIQTEKLLKRVQELEQEVKRLKKEQANNKDSNIRENSSGAGGKPKRAFDFSAHGQRHVALKIAYLGWGYQGFASQENTSNTIEEKLFEALTKTRLVENRQTSNYHRCGRTDKGVSAFGQVISLDLRSHIPKGRDSEHFNLKNEVNDVATEIRYTHILNRVLPPDIRVLAWAPVETSFSARFSCLERTYRYFFPRANLDIVTMNYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQRVGQNLGEEGWQEPFQLCQFEVTGQAFLYHQVRCMMAVLFLIGQGMEKPEVIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENIKWIYDREVQEFNVTHLQQLWANHAVKTQMLYSMLQGLDSVALPCGTGPKMDGMIEWRNVKPSVTKQTSAFVEGVKMRTYKPLMDRPKCQGLESRIQHFVRRGRIEHPHLFHEEETKAKRDCSDTLEEENTVFEKPTKRICVDTELKSII", "length": 481, "header": "tr|F1N5P3-1|F1N5P3_BOVIN Isoform 1 of tRNA pseudouridine(38/39) synthase OS=Bos taurus OX=9913 GN=PUS3 PE=3 SV=1 CANONICAL=F1N5P3-1" }, "isoforms": [ { "isoform_ac": "F1N5P3-1", "url": "https://www.uniprot.org/uniprotkb/F1N5P3/entry", "sequence": { "sequence": "MAENDVDRIQTEKLLKRVQELEQEVKRLKKEQANNKDSNIRENSSGAGGKPKRAFDFSAHGQRHVALKIAYLGWGYQGFASQENTSNTIEEKLFEALTKTRLVENRQTSNYHRCGRTDKGVSAFGQVISLDLRSHIPKGRDSEHFNLKNEVNDVATEIRYTHILNRVLPPDIRVLAWAPVETSFSARFSCLERTYRYFFPRANLDIVTMNYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQRVGQNLGEEGWQEPFQLCQFEVTGQAFLYHQVRCMMAVLFLIGQGMEKPEVIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENIKWIYDREVQEFNVTHLQQLWANHAVKTQMLYSMLQGLDSVALPCGTGPKMDGMIEWRNVKPSVTKQTSAFVEGVKMRTYKPLMDRPKCQGLESRIQHFVRRGRIEHPHLFHEEETKAKRDCSDTLEEENTVFEKPTKRICVDTELKSII", "length": 481, "header": "tr|F1N5P3-1|F1N5P3_BOVIN Isoform 1 of tRNA pseudouridine(38/39) synthase OS=Bos taurus OX=9913 GN=PUS3 PE=3 SV=1 CANONICAL=F1N5P3-1" }, "locus": { "chromosome": "29", "start_pos": 29250413, "end_pos": 29248201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019065.4", "url": "https://www.ensembl.org/id/ENSBTAT00000019065.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019065.2", "url": "https://www.ensembl.org/id/ENSBTAP00000019065.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZYZ1-1", "protein_name": "tRNA pseudouridine(38/39) synthase", "gene_name": "PUS3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANGSWATDREQLLRRVRDLEEEVKQLQEKLSEGKEGTAVKDTPSTSRKSKKQQQRPFDFSAHGRRHVALRIAYLGWGYQGFASQENTSNTIEEKLFEALKKTRLVDDRQTSNYHRCGRTDKGVSAFGQVRMDLQVPLGMVELRMGLLADGDEPSAHCVTVQVISLDLRSNLSEEKKLNGCTGDSEGKSSKSEEELRYTHILNRVLPPDIRVLAWAPVEPDFSARFSCLKRTYRYFFPCADLDVALMHTAAQRYVGTHDFRNLCKMDVANGVINFQRTILSAQVTWADGGAESGLRDPFRLCQFEVTGQAFLYHQVRCMMAILFLIGQRMEGPEIIDELLDVEKNPRKPQYSMAVEFPLVLYDCEFENIQWHYDREVQEFNVTHLQQLWASYAVKTQVLHSMLRGLDTAPMAAGKDPGNAAPVLWGDLKPPVHNQASSFVEGVRARAYKPLLERPRCEGLESRIQQCLRRGRSQAERAAKRLCTGEGPGGTS", "length": 492 }, "evidence": [ { "id": "F1N5P3", "url": "https://omabrowser.org/oma/group/F1N5P3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9BZE2-1", "protein_name": "tRNA pseudouridine(38/39) synthase", "gene_name": "PUS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYNDTDRNQTEKLLKRVRELEQEVQRLKKEQAKNKEDSNIRENSAGAGKTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNNTIEEKLFEALTKTRLVESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRILAWAPVEPSFSARFSCLERTYRYFFPRADLDIVTMDYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQLVGQSPGEGRWQEPFQLCQFEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENVKWIYDQEAQEFNITHLQQLWANHAVKTHMLYSMLQGLDTVPVPCGIGPKMDGMTEWGNVKPSVIKQTSAFVEGVKMRTYKPLMDRPKCQGLESRIQHFVRRGRIEHPHLFHEEETKAKRDCNDTLEEENTNLETPTKRVCVDTEIKSII", "length": 481 }, "evidence": [ { "id": "F1N5P3", "url": "https://omabrowser.org/oma/group/F1N5P3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JI38-1", "protein_name": "tRNA pseudouridine(38/39) synthase", "gene_name": "Pus3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAENTDRNQIEKLLNRVKELEQEVERLKKKKEQANNIKDSSIRENSLGSGKAKRAFDFSAHGRRHVALKIAYLGWGYQGFASQENTSNTIEEKLFEALTKTRLVESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPTSRDSEDSNLKHEADDLAKEIRYTHILNRVLPADIRVLAWAPVEPSFSARFSCLERTYRYFFPRADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVINFQRTILCAQVQLVAQSPGEERRQEPFQLCQFEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIQKNPQKPQYSMAVEFPLVLYDCKFENTKWIYDHEVQEFNVTHLQQLWANHAVKTHMLYSMLQGLDSVMVTCAAGTKMDEATEWRNIQPPVIKHTSAFVEGVKMRTYKPLMDRPKCQGLESRIRHFVSRGRIEHPHLLHKEEIKARRDCADKEENTVVENPSKRVCIIDAEINSIA", "length": 481 }, "evidence": [ { "id": "F1N5P3", "url": "https://omabrowser.org/oma/group/F1N5P3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W282-1", "protein_name": "Pseudouridine synthase I TruA alpha/beta domain-containing protein", "gene_name": "Dmel\\CG3045", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSATNDKKVVINKRLKGLSREALEKLTQTELIDKVIQLEAYNFQLRNLLQKKLSEKDKHDKEYSGLIGNEAEGKVSQVAKTSSKVQKIRKFDWSSAHKRHVLLKITYFGWDYQGFACQEDSNDTIESNLFRALARTCLIESRATSNYHRCGRTDKEVSAFCQVISIDLRSKHPPESQLDPTALSSEIDYCGLLNRVLPKNIQCVAWMPLRSPVYSARFDCVSRTYRYYFPKGDLDIAAMRKACDLLVRHADFRNFCKMDVHNGVTNYMRNLQSARVEACDQTNHTNSGYDMYYLEIQANAFLWHQIRCIMAVLLLVGQKKENPGVISDLLDVESNPCKPQYTPAIGLPLNLFRCDFRDHTTRSVNHPSSGDADEEAMDTAADESNDLNAPEHLERDLTAWIYNEENLQKLIENTQCEWTQFSVKSTMIRNVLQQLENLFEENFKPKEKVLAQVILLQDSVNPRQYQPLLERKRCESLENRIEHFVKKQRLIVKNETETE", "length": 499 }, "evidence": [ { "id": "F1N5P3", "url": "https://omabrowser.org/oma/group/F1N5P3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA pseudouridine synthesis", "id": "GO:0031119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031119", "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "pmid": "" }, { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "pmid": "" }, { "name": "tRNA pseudouridine(38/39) synthase activity", "id": "GO:0160154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160154", "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N5P3", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "42564", "name": "", "equation": "uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SX07-1", "F1N5P3-1" ], "evidence": [ { "id": "42564", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42564" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1N5P3", "gene_name": "PUS3", "activity": [ { "ec_number": "5.4.99.45", "activity": "uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA.", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ] }, { "ec_number": "5.4.99.45", "activity": "", "evidence": [ { "id": "F1N5P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5P3" } ] } ] }, { "uniprot_ac": "Q3SX07", "gene_name": "PUS3", "activity": [ { "ec_number": "5.4.99.45", "activity": "uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA.", "evidence": [ { "id": "Q3SX07", "database": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5R4-1", "uniprot_ac": "F1N5R4", "uniprot_id": "F1N5R4_BOVIN", "mass": { "chemical_mass": 69816.0, "monoisotopic_mass": 69816.0 }, "refseq": {}, "gene_names": [ { "name": "COG8", "type": "recommended", "evidence": [ { "id": "F1N5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5R4" } ] } ], "protein_names": [ { "name": "Conserved oligomeric Golgi complex subunit 8", "type": "recommended", "evidence": [ { "id": "F1N5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5R4/entry#names_and_taxonomy" } ] }, { "name": "COG complex subunit 8", "type": "synonym", "evidence": [ { "id": "F1N5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5R4/entry#names_and_taxonomy" } ] }, { "name": "Component of oligomeric Golgi complex 8", "type": "synonym", "evidence": [ { "id": "F1N5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5R4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5R4", "url": "https://www.uniprot.org/uniprotkb/F1N5R4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "COG8", "url": "https://www.uniprot.org/uniprotkb/F1N5R4", "locus": { "chromosome": "18", "start_pos": 36474044, "end_pos": 36480940, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001665", "url": "https://www.ensembl.org/id/ENSBTAG00000001665" } ] } } ], "crossref": [ { "id": "F1N5R4", "url": "https://alphafold.ebi.ac.uk/entry/F1N5R4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001665", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001665", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QRCIHGV", "url": "https://omabrowser.org/oma/group/QRCIHGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N5R4", "url": "https://www.orthodb.org/?gene=F1N5R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21311:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21311:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04124", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04124", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N5R4", "url": "https://www.uniprot.org/uniprotkb/F1N5R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5R4-1", "url": "https://www.uniprot.org/uniprotkb/F1N5R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATATIPSSTTASATTTATAAALGEVEDEGLLASLFRDRFPEAQWRERPDVGRYLRELSGSGLERLRREPERLAEERAQLLQQTRDLAFANYKTFIRGAECTERIHRLFGDVEESLGRLLDRLPSFQQSCRNFVKEAEEISSNRRMNTLTLNRHTEILEILEIPQLMDTCVRNSYYEEALELAAYVRRLERKYSSIPVIQGIVNEVRQSMQLMLSQLIQQLRTNIQLPACLRVIGFLRQMDVFTEAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEACRVHLFDIITQYRAIFSDEDPLLPPAMGEHMVNESAIFHGWVLQKVSQFLQVLETDLNRGIGSRLDSLLGQCMYFGLSFSRVGADFRGQLVPVFQQVAISTFQKAIQEAVEKFQDEMNSYTLISTPAVLGSSALPAAAPVTQPGTLQPPMVLLDFPPLACFLNSILVAFNDLRLCCPVALAQEVTRALEDALDKVTKVILAFHRAEEAAFSSGEQELFVQFCTVFLEDLVPYLNRCLQVLFPPAQIAQTLGIPPTQLSKYGNLGHVNVSVVQEPLAFILPKREPVFCLDKELVPELPAPAPALPPNAPSPEPVTPVTPAVPDAGQEEVESAGPPQPDEPSAGI", "length": 626, "header": "tr|F1N5R4-1|F1N5R4_BOVIN Isoform 1 of Conserved oligomeric Golgi complex subunit 8 OS=Bos taurus OX=9913 GN=COG8 PE=3 SV=1 CANONICAL=F1N5R4-1" }, "isoforms": [ { "isoform_ac": "F1N5R4-1", "url": "https://www.uniprot.org/uniprotkb/F1N5R4/entry", "sequence": { "sequence": "MAATATIPSSTTASATTTATAAALGEVEDEGLLASLFRDRFPEAQWRERPDVGRYLRELSGSGLERLRREPERLAEERAQLLQQTRDLAFANYKTFIRGAECTERIHRLFGDVEESLGRLLDRLPSFQQSCRNFVKEAEEISSNRRMNTLTLNRHTEILEILEIPQLMDTCVRNSYYEEALELAAYVRRLERKYSSIPVIQGIVNEVRQSMQLMLSQLIQQLRTNIQLPACLRVIGFLRQMDVFTEAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEACRVHLFDIITQYRAIFSDEDPLLPPAMGEHMVNESAIFHGWVLQKVSQFLQVLETDLNRGIGSRLDSLLGQCMYFGLSFSRVGADFRGQLVPVFQQVAISTFQKAIQEAVEKFQDEMNSYTLISTPAVLGSSALPAAAPVTQPGTLQPPMVLLDFPPLACFLNSILVAFNDLRLCCPVALAQEVTRALEDALDKVTKVILAFHRAEEAAFSSGEQELFVQFCTVFLEDLVPYLNRCLQVLFPPAQIAQTLGIPPTQLSKYGNLGHVNVSVVQEPLAFILPKREPVFCLDKELVPELPAPAPALPPNAPSPEPVTPVTPAVPDAGQEEVESAGPPQPDEPSAGI", "length": 626, "header": "tr|F1N5R4-1|F1N5R4_BOVIN Isoform 1 of Conserved oligomeric Golgi complex subunit 8 OS=Bos taurus OX=9913 GN=COG8 PE=3 SV=1 CANONICAL=F1N5R4-1" }, "locus": { "chromosome": "18", "start_pos": 36480914, "end_pos": 36474219, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002179.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002179.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002179.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002179.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 597, "start_aa": "Thr", "end_pos": 597, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr597", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 600, "start_aa": "Thr", "end_pos": 600, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr600", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-BTA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-BTA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XSI4-1", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "gene_name": "GCOG8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAEEERLLAWLRGPAAAGPGGAELAAYVAELAALGLAELGREPARLAAERERVGAETRRLAFEHYRAFIRSAECTGRAGRGFGGIESRLGSLLERLPALQDACRNFMRDAEAIACSRRMNSLTLNRHTEILEILEIPQLMDTCVRNRYYEEALELAAYVRRLEKKYSSIPVIQGIVAEVRQSTQLMLNELIQQLRTNIPLPTCLRVIGYLRRMDVFTEAELRIKFLQARDAWLRSIQASIPEDDPYFHLTKTVEACRVHLFDIITQYRAIFSDEEPLLAPEQPSLNEGAIFHGWVLQKVSEFLQVLERDLQRGVGSRLDSLLGQCMYFGLSFSRVGADFRGQLAPIFQRVAATTFSKAVEEAVEKFQEEMNSYTLISAPAVLGSAAAVPVPSAQPGTLQPPMVLLDFPPLACFLNGLLVAFNDLRLCCPIALAQDVAACLKDALGKVTKIILAFHRAEEAAFSGREQELFVQFCAAFLEDLLPYLNRCLQVLFPPAQIAQALGIPPAQLQRYGHLGCVDVDALRELLAPVLPAQEAELPPGEEEPSPQSPALTLHPTQPEGTGPGEPPPEQGREEPVDPAPGAVLLDGSGHGGERPAV", "length": 599 }, "evidence": [ { "id": "F1N5R4", "url": "https://omabrowser.org/oma/group/F1N5R4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q84K25-1", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "gene_name": "COG8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAMEVGEMSQPEATASLLSLASATQQPYVSELLSFTLDRLHKEPELLRVDAERIQRQMQEVAVGNYRAFITAADALLAIRQEVSSIDKHLESLIGEVPKLTSGCTEFIDSAENILEKRKMNQALLANHSTLLDLLEIPQLMDTCVRNGNFDEALDLEAFVSKLATLHPKLPVIQALAAEVRQTTQSLLSQLLQKLRSNIQLPECLRIIGYLRRIGVFGEYEMRLQFLRCREAWLTGILEDLDQKNAYEYLKGMINCHRMHLFDVVNQYRAIFSDDTSGSEENYDGGLLFSWAMHQITSHLKTLKIMLPKITEGGSLSNILDQCMYCAMGLGGVGLDFRGLLPPLFEEAVLNLFSKNMSTAVENFQLVLDSHRWVPLPSVGFPSSGINEDSKDDVTPPSYLMEHPPLAVFINGVSSALNELRPCAPLSLKNVVAHELIKGLQAVSDSLLRYNTTRMLRLSESNLFLSLCRAFVEVVFPHCATCFGRCYPGGATIVMDAKSAYEGLGRILAASSSQEPSNKSPKVISTDTKDASENGVASQPEEKQAENPNAKEEDNSPIPLQTPEITPES", "length": 569 }, "evidence": [ { "id": "F1N5R4", "url": "https://omabrowser.org/oma/group/F1N5R4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96MW5-1", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "gene_name": "COG8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAATIPSVATATAAALGEVEDEGLLASLFRDRFPEAQWRERPDVGRYLRELSGSGLERLRREPERLAEERAQLLQQTRDLAFANYKTFIRGAECTERIHRLFGDVEASLGRLLDRLPSFQQSCRNFVKEAEEISSNRRMNSLTLNRHTEILEILEIPQLMDTCVRNSYYEEALELAAYVRRLERKYSSIPVIQGIVNEVRQSMQLMLSQLIQQLRTNIQLPACLRVIGYLRRMDVFTEAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEASRVHLFDIITQYRAIFSDEDPLLPPAMGEHTVNESAIFHGWVLQKVSQFLQVLETDLYRGIGGHLDSLLGQCMYFGLSFSRVGADFRGQLAPVFQRVAISTFQKAIQETVEKFQEEMNSYMLISAPAILGTSNMPAAVPATQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALAQDVTGALEDALAKVTKIILAFHRAEEAAFSSGEQELFVQFCTVFLEDLVPYLNRCLQVLFPPAQIAQTLGIPPTQLSKYGNLGHVNIGAIQEPLAFILPKRETLFTLDDQALGPELTAPAPEPPAEEPRLEPAGPACPEGGRAETQAEPPSVGP", "length": 612 }, "evidence": [ { "id": "F1N5R4", "url": "https://omabrowser.org/oma/group/F1N5R4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJA2-1", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "gene_name": "Cog8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAALPLQPSTTASATTTATAVALGEVEDEGLLASLFRDRFPEAQWREKPDVGRYLRELSGSGLDRLRREPERLAEERAQRLQQTRDLAFANYKTFIRGAECTERIHRLFGDVEASLGRLLDRLPRFQQSCRNFVKEAEEISSSRRMNTLTLNRHTEILEILEIPQLMDTCVRNSYHEEALELAAYVRRLERKYSSIPVIQGIVNEVRQSMQLMLSQLIQQLRTNIQLPACLRVIGYLRRMDVFTEAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEACRVHLFDIITQYRAIFSDEDPLLPPAMGEYTVNEGAIFHGWVLQKISQFLQVLETDLYRGIGGRLDSLLGQCMYFGLSFSRVGADFRGQLAPVFQRVAISTFQKAVEEAVEKFQDEMTSYTLISTAAILGSSNTPATVPATQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALAQDVTGTLENALTKVTKTILAFHRAEEAVFSSGEHEIFVQFCTAFLEDLVPYLNRCLQVLFPPAQIAQTLGISPTQLSKHGNLGHVNISAIQEPLAFILPKRETVFCLDEQELGPDLVAPAPELPAEQRSMEPVTEKREPGEPLPQEPMEGEPLPAEPPSEGGAIGSVPCPQPGEQP", "length": 640 }, "evidence": [ { "id": "F1N5R4", "url": "https://omabrowser.org/oma/group/F1N5R4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKH0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "gene_name": "Cog8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFPDKMDLENERVLKLIFPDGVPDNLRGNPELDNYLAKLGTCKVEQLKKEQTRLAEEARTILEQTQDLAISNYRTFITTAENSRSIFSEFLRSEQQLDTLVSKLPDLSVQCERFLQDSAELNEQRRLNSITLQKNAQLLEVLELPQLMERCIREGRYEEALELAAYATRLGQHQGHIPVVTSIVRSVEALWHNMLVQLVAQLRTDLQLPKCLQIVGYLRRMQAFGDNELRLKFLQARDAWLTSCLEAIPTADAQQHLSKTIEITRINLFNIITQYRAIFPEDEGTLKTQSSLRPLQGVSCNGDRLFQAWLHNKISDFLQTLERDLQLGVGSVETVLGQCMYFGLSFSRVGADFRALMAPIFVGVIRRRFESSVEQVDEQFERELERFTLINKVALHSHARKQVDPEQESYAPPEALLDFYPLAALCNGYLSALNELRLCAPLALATDVTRCLQHSLQQAAQRVLAFYRQEQQAFAGSEREAFVRLCSCLAYDLVPYIQRCIHGVFPPQSLTVHLGISLLQLEQQQLTYLQQTRILEPLKHLLPTKALVQPQDKVMEAKPSAGVPVTAEG", "length": 570 }, "evidence": [ { "id": "F1N5R4", "url": "https://omabrowser.org/oma/group/F1N5R4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1N5R4", "url": "https://www.uniprot.org/uniprotkb/F1N5R4" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "F1N5R4", "url": "https://www.uniprot.org/uniprotkb/F1N5R4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1N5R4", "url": "https://www.uniprot.org/uniprotkb/F1N5R4" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F1N5R4", "url": "https://www.uniprot.org/uniprotkb/F1N5R4" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": 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from the N-terminal Met of newly synthesized proteins.", "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7#function" }, { "database": "UniProtKB", "id": "ARBA00037114", "url": "https://www.uniprot.org/uniprotkb/ARBA00037114#function" }, { "database": "UniProtKB", "id": "RU362111", "url": "https://www.uniprot.org/uniprotkb/RU362111#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDF", "url": "https://www.uniprot.org/uniprotkb/F1N5S7", "locus": { "chromosome": "18", "start_pos": 36471273, "end_pos": 36473815, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001663", "url": "https://www.ensembl.org/id/ENSBTAG00000001663" } ] } } ], "crossref": [ { "id": "F1N5S7", "url": "https://alphafold.ebi.ac.uk/entry/F1N5S7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001663", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001663", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00487", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00487", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR023635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N5S7", "url": "https://www.orthodb.org/?gene=F1N5S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10458", "url": 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"MGLLGAGLLLRWLRAALLWGERVAVGGARAYSSTPTQDGLEGPARRRSYWRYVRRLVQGTPEPPYPRVCQVGDPALRAVAAPVEPAQLAGPELQRLVERLVQVMRRRHCVGLSAPQLGVPLQVLALEFPETLFRACAPRVREARQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLACVPRFQAVQISGLDPRGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSKTFTNIHWMEVND", "length": 244, "header": "tr|F1N5S7-1|F1N5S7_BOVIN Isoform 1 of Peptide deformylase OS=Bos taurus OX=9913 GN=PDF PE=3 SV=4 CANONICAL=F1N5S7-1" }, "isoforms": [ { "isoform_ac": "F1N5S7-1", "url": "https://www.uniprot.org/uniprotkb/F1N5S7/entry", "sequence": { "sequence": "MGLLGAGLLLRWLRAALLWGERVAVGGARAYSSTPTQDGLEGPARRRSYWRYVRRLVQGTPEPPYPRVCQVGDPALRAVAAPVEPAQLAGPELQRLVERLVQVMRRRHCVGLSAPQLGVPLQVLALEFPETLFRACAPRVREARQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLACVPRFQAVQISGLDPRGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSKTFTNIHWMEVND", "length": 244, "header": "tr|F1N5S7-1|F1N5S7_BOVIN Isoform 1 of Peptide deformylase OS=Bos taurus OX=9913 GN=PDF PE=3 SV=4 CANONICAL=F1N5S7-1" }, "locus": { "chromosome": "18", "start_pos": 36473815, "end_pos": 36472277, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002176.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002176.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002176.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002176.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptide deformylase activity", "id": "GO:0042586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042586", "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ], "pmid": "" }, { "name": "post-translational protein modification", "id": "GO:0043687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043687", "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "F1N5S7", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24420", "name": "", "equation": "N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N5S7-1" ], "evidence": [ { "id": "24420", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24420" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1N5S7", "gene_name": "PDF", "activity": [ { "ec_number": "3.5.1.88", "activity": "N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate.", "evidence": [ { "id": "F1N5S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ] }, { "ec_number": "3.5.1.88", "activity": "", "evidence": [ { "id": "F1N5S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5S7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5S7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 244, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5S7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5S7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.88", "ec_name": "N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate.", "evidence": [ { "id": "3.5.1.88", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.88" }, { "id": "3.5.1.88", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.88" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], 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"function": [ { "annotation": "Involved in cardiomyocyte differentiation.", "evidence": [ { "database": "UniProtKB", "id": "F1N5U0", "url": "https://www.uniprot.org/uniprotkb/F1N5U0#function" }, { "database": "UniProtKB", "id": "ARBA00053245", "url": "https://www.uniprot.org/uniprotkb/ARBA00053245#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5U0", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ALPK3", "url": "https://www.uniprot.org/uniprotkb/F1N5U0", "locus": { "chromosome": "21", "start_pos": 22511555, "end_pos": 22458517, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001618", "url": "https://www.ensembl.org/id/ENSBTAG00000001618" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001618", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001618", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WPPAINR", "url": "https://omabrowser.org/oma/group/WPPAINR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR47091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47091:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47091:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N5U0", "url": "https://www.uniprot.org/uniprotkb/F1N5U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5U0-1", "url": "https://www.uniprot.org/uniprotkb/F1N5U0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAGPGAINRGARQPRAREAAGGAGLTGRGRERGQGQEAGRAGSSMGSRRAPGRGWGSGGRSEAGGDGEDDGPVWIPSPASRSYLLSVRPETSLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSDVRFTCIVTGYPEPEVTWYKDDTELDRYCGLPKYEIMHQGNRHTLQLYRCREEDAAIYQASARNAKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKMREIEQSWKHGKEAVGEADALRKLSPDRFQRKRRLSGAEVPVPSAPAREVEDGPLVAWQEGDTEPGQHPGLGLINSLASGEVTTNGEAAPENGEDGERGLLTYICEAMELGPQRAPKKESGAKKKKKDMEPKQGVRKPEMEKAAQSHRASENRFPSSDKPDSRGTQGPLDVEQFQTRPRGRAARGPGSPGADGTRKPASGAGTPDQAQKTQAPAPVPGPEPEVYFSLKDMYLESTRADQPQMEAEAQTPRGRTPGQRPSRRESSEAGGERGPAAPGQPVPSAPQPTRPFNRKRFAPPKLKGEPTASSKPDSSLSQDSEPGAQSSGKTPCQTSAQVPTPPARRRHSTRDSPLQGQAGPSAPGKVQESQATIAPAPAGSSSDPASAGHSTSRSQGIIEPMDAETQEDRRMSVDQKTGGEKNTEVDRKMQVDGRTQGDQTEASQWTQADRMTQVDVVMQGSRRSESDRNSQEDVMAQGRVGTQAEERTQEDGWVQQDKGTQSEGSTPSTTKGHSEKASMTSLSPHSRAPKRPPSEDPRSPQVIEGFGQSQDEFSVPDKPGCVLTSDKTPGPASGNQEEAVLGPLVGGLAPRAQLPPEVRSEPVGGERSGGLEWSTPGRDKPREGLFQGPREEELGRVPPAALGGRPPGGLGPEGRPLPSPPEAGLTRHSQEGLPSTPASQPRSAAAFPPSEDKTLLSSAPSLHLGPGTASPSHPPETVAANSEGPCAKVPDADGRTSGPRTCDPGLIDSLKNYLLLLLKLSSSEASGGGPESQGEAAAGLPAPLPTLAPTIEVAGLSPRTSRRILERVENNHLVQSAQTLLLSPGTSRRLTGLLDREVEAGRQALAAARRPGPSPLSVPAIVVGEAEGPGLASGGSSEGEGQLPLEGPGLLEVSRESSMGGLLREEGGGQAAPGQGLLSTESRAQEPSPEEEAPGEALPAATPEELALGARRKRFLPKVKAAGDGEGTKPEERESPSVSPRGPRKALAPRSPGTPGRERRSPTQGRKAGMLEVPRAEEELAAGDPAPSPKAGSLDAELALEEGNQDALAKSRKAKDLLKAPQVIRKIRVEQFPDASGSLKLWCQFFNILSDSVLTWAKDQRPVGEVGRSAGDEGPAALAIVQASPVDCGVYRCTIHNEHGSASTDFCLSPEVLSGFISREEGQVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGHGCSLRKASQAKVIYGLEPIFESGRTCVIKVSSLLVFGPSSETSLLGRNYDVTIQGCKIQNMSREYCKIFAAEARAAPGFGEVPEIIPLYLIYRPANNIPYATLEEDLGQPLESYCSRDWGCAAAPAAPSSSEAVWKCQTFQHWLYLWTNGSFLVTDLAGVNWKMTDVQIATKLRGYQGLKESCFPALLDQFASSHQCNTFCEMLGLKPLKGPEATHPQAKAKGSKSPSAGRKGPQLSPQPQKKGPPSPQGTRKSASGSKATPQASEVVATQLLGQSPIQEGASKAQGMR", "length": 1726, "header": "tr|F1N5U0-1|F1N5U0_BOVIN Isoform 1 of Alpha-protein kinase 3 OS=Bos taurus OX=9913 GN=ALPK3 PE=3 SV=3 CANONICAL=F1N5U0-1" }, "isoforms": [ { "isoform_ac": "F1N5U0-1", "url": "https://www.uniprot.org/uniprotkb/F1N5U0/entry", "sequence": { "sequence": "MTAGPGAINRGARQPRAREAAGGAGLTGRGRERGQGQEAGRAGSSMGSRRAPGRGWGSGGRSEAGGDGEDDGPVWIPSPASRSYLLSVRPETSLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSDVRFTCIVTGYPEPEVTWYKDDTELDRYCGLPKYEIMHQGNRHTLQLYRCREEDAAIYQASARNAKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKMREIEQSWKHGKEAVGEADALRKLSPDRFQRKRRLSGAEVPVPSAPAREVEDGPLVAWQEGDTEPGQHPGLGLINSLASGEVTTNGEAAPENGEDGERGLLTYICEAMELGPQRAPKKESGAKKKKKDMEPKQGVRKPEMEKAAQSHRASENRFPSSDKPDSRGTQGPLDVEQFQTRPRGRAARGPGSPGADGTRKPASGAGTPDQAQKTQAPAPVPGPEPEVYFSLKDMYLESTRADQPQMEAEAQTPRGRTPGQRPSRRESSEAGGERGPAAPGQPVPSAPQPTRPFNRKRFAPPKLKGEPTASSKPDSSLSQDSEPGAQSSGKTPCQTSAQVPTPPARRRHSTRDSPLQGQAGPSAPGKVQESQATIAPAPAGSSSDPASAGHSTSRSQGIIEPMDAETQEDRRMSVDQKTGGEKNTEVDRKMQVDGRTQGDQTEASQWTQADRMTQVDVVMQGSRRSESDRNSQEDVMAQGRVGTQAEERTQEDGWVQQDKGTQSEGSTPSTTKGHSEKASMTSLSPHSRAPKRPPSEDPRSPQVIEGFGQSQDEFSVPDKPGCVLTSDKTPGPASGNQEEAVLGPLVGGLAPRAQLPPEVRSEPVGGERSGGLEWSTPGRDKPREGLFQGPREEELGRVPPAALGGRPPGGLGPEGRPLPSPPEAGLTRHSQEGLPSTPASQPRSAAAFPPSEDKTLLSSAPSLHLGPGTASPSHPPETVAANSEGPCAKVPDADGRTSGPRTCDPGLIDSLKNYLLLLLKLSSSEASGGGPESQGEAAAGLPAPLPTLAPTIEVAGLSPRTSRRILERVENNHLVQSAQTLLLSPGTSRRLTGLLDREVEAGRQALAAARRPGPSPLSVPAIVVGEAEGPGLASGGSSEGEGQLPLEGPGLLEVSRESSMGGLLREEGGGQAAPGQGLLSTESRAQEPSPEEEAPGEALPAATPEELALGARRKRFLPKVKAAGDGEGTKPEERESPSVSPRGPRKALAPRSPGTPGRERRSPTQGRKAGMLEVPRAEEELAAGDPAPSPKAGSLDAELALEEGNQDALAKSRKAKDLLKAPQVIRKIRVEQFPDASGSLKLWCQFFNILSDSVLTWAKDQRPVGEVGRSAGDEGPAALAIVQASPVDCGVYRCTIHNEHGSASTDFCLSPEVLSGFISREEGQVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGHGCSLRKASQAKVIYGLEPIFESGRTCVIKVSSLLVFGPSSETSLLGRNYDVTIQGCKIQNMSREYCKIFAAEARAAPGFGEVPEIIPLYLIYRPANNIPYATLEEDLGQPLESYCSRDWGCAAAPAAPSSSEAVWKCQTFQHWLYLWTNGSFLVTDLAGVNWKMTDVQIATKLRGYQGLKESCFPALLDQFASSHQCNTFCEMLGLKPLKGPEATHPQAKAKGSKSPSAGRKGPQLSPQPQKKGPPSPQGTRKSASGSKATPQASEVVATQLLGQSPIQEGASKAQGMR", "length": 1726, "header": "tr|F1N5U0-1|F1N5U0_BOVIN Isoform 1 of Alpha-protein kinase 3 OS=Bos taurus OX=9913 GN=ALPK3 PE=3 SV=3 CANONICAL=F1N5U0-1" }, "locus": { "chromosome": "21", "start_pos": 22510551, "end_pos": 22458575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002122.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002122.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002122.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002122.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1228, "start_aa": "Thr", "end_pos": 1228, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1228", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 740, "start_aa": "Thr", "end_pos": 740, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr740", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 910, "start_aa": "Thr", "end_pos": 910, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr910", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZH28-1", "protein_name": "Alpha-protein kinase 3", "gene_name": "Alpk3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSRRALGRGWGLGGRAGTGGDGEDDGPVWTPGPASRSYLLSVRPEASLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSDVRFTCIVTGYPEPEVTWYKDDIELDRYCGLPKYEITHQGNRHTLQLYRCREEDAAIYQASARNTKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKMREIEQSWKHGKEASGEADTLRKISPDRFQRKRRLSGAEEAVLPAPLRGTEEGPSAAWQEGEAESTQHPGLGMINSFAPGEAPTNGEPAPENGEDGEHGLLTYICEVMELGPQNTPPKESGAKKKRKDEESKPGGQKPELGKAEGSQCSSENGIPSSDKLNSSRREKKSRDVQPTQNQTRDRVARGPGPSGIESTRKTASVLGTQDKVQDVPALAPAPAPAPAPVPVPAPAPVPSLSSEQVYFSLKDMFMESTRAGRSQEEEKSPPPSTRVAGESPSGKVPVKARGEKVPMVSGQPTSSTVPPPIKPLNRKRFAPPKSKVESTTSSSSSQTPESVAQSLGKAPPPASAQVPTPPARRRHGTRESPLQGQTSHKTPGEALESPATMAPATSASSSSDTISVGHSTSGNQGVTEPMDTETQEEGRTLANGRTSGRQKTQTDGKLQVDGRTQGDEAQTLQRTQTNEKAPMNVVTQGSERPESDRSSQKDLVTQRRVDTQVGQTQAGERWQQDPRDARIQEEKETQSVGSIPTALETQPEQPSVVSLSSVPGALKLSPSECPTEPQATECSERSTEASYIQEKSGLMLGSEEADFRSHENTLLGPPSGNHTYSTQLPTEGNSEHLVGETHQRPEWLGEAKQEDSLLQSPKKEQLQETLYVDLAIGHSADLSQEVPSLPSLPGTDLTNSLQEGLPSTTASQHTNADVPLPSPDQDLPSSAPTLQLGPGSPTQSHPPEVMATSSEGACAKEPDVDGRSSGTRSCDPGLIDSLKNYLLLLLKLSSPEAGEARAESQEVPATGGLTSSSALVPTVEVAGLSPRTSRRILDRVENNHLVQSAQTLLLSPCTSRRLTGLLDREVQAGQQALAAAQCSRGPCPSPSPLTIPAIVVGEEGSATGEGEDSRERTSQESDKAGLLGEVDGQTVESRTQEPCQEEAIPGEALTGLPAATPEELALGARRKRFLPKVRAGSDGEVNKAEERESPTVSPRGPRKGLAPGSPGTPGRERRSPTQARKASMLEVPGTEEEPASGDLVTRPKASGLESEPAVDEGKQEALAKPRKAKDLLKAPQVIRKIRVEQFPDSSGSLKLWCQFFNIVSDSVLTWAKDQHLVGEVSRSAGDEGPAALAIVQASPTDCGLYRCTIQNEHGSASTDFRLSPEVLSGFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGHGLQKASRAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLLGRNYDVTIQGCKIQNMSREYCKIFAAETRAASGFGEVPEIIPLYLIYRPANNIPYATLEEDLGKPLQTYCSRQWSCAGAPAASSSLEPVQKCQTFQHWLYQWTNGSFLVTDLAGADWKMTDVEIATKLRGYQGLKESCFPALLDQFASSHQCNTYCEMLGLKPLKGPEGAHPQTKAKGSKSPSAGRKGSQLSPQPQKKGLPSPQGSRKSAPSSRATPQASQEATLQLLGQPPAQEGSSKAQGMR", "length": 1684 }, "evidence": [ { "id": "F1N5U0", "url": "https://omabrowser.org/oma/group/F1N5U0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q924C5-1", "protein_name": "Alpha-protein kinase 3", "gene_name": "Alpk3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSRRAAGRGWGLGGRAGAGGDSEDDGPVWTPGPASRSYLLSVRPEASLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSDVRFTCIVTGYPEPEVTWYKDDIELDRYCGLPKYEITHQGNRHTLQLYRCQEEDAAIYQASARNTKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKMREIEQSWKHGKEASGEADTLLRKISPDRFQRKRRLSGVEEAVLSTPVREMEEGSSAAWQEGETESAQHPGLGLINSFAPGEAPTNGEPAPENGEDEERGLLTYICEVMELGPQNSPPKESGAKKKRKDEESKPGEQKLELEKAEGSQCSSENVVPSTDKPNSSRREKSTDTQPAQTQPRGRVARGPGIESTRKTASVLGIQDKVQDVPAPAPAPVPAPALAPAPVPVPAPTPVPSRSSEQVYFSLKDMFMETTRAGRSQEEEKPPPPSTRVAGESPPGKTPVKSRLEKVPMVSSQPTSSMVPPPIKPLNRKRFAPPKSKVESTTTSLSSQTSESMAQSLGKALPSASTQVPTPPARRRHGTRDSPLQGQTSHKTPGEALESPATVAPTKSANSSSDTVSVDHDSSGNQGATEPMDTETQEDGRTLVDGRTGSRKKTHTDGKLQVDGRTQGDGAQDRAHASPRTQAGEKAPTDVVTQGSERPQSDRSSWKNLVTQRRVDMQVGQMQAGERWQQDPGDARIQEEEKETQSAAGSIPVAFETQSEQLSMASLSSLPGALKGSPSGCPRESQAIECFEKSTEAPCVQERSDLMLRSEEAAFRSHEDGLLGPPSGNRTYPTQLPPEGHSEHLGGQTHQRSEQEDSLSQCPKKEQPQEPLHVGLSGGHSTGLSQEVPAMPSLPGTGLTSSLQEELPGTAASLHTNTDVPLPSRDQDFPSSAPTLQLGPGSPTQSHPPEAMATSSEGACAKEPNVDGRSSGTRSCDPGLIDSLKNYLLLLLKLSSPETSEARAESQEVADTGGLTSSSTLVPTMEVAGLSPRTSRRILERVENNHLVQSAQTLLLSPCTSRRLTGLLDREVQAGQQALAAAQCSRGPCPTPLTIPAIVVGEEGSAGEDSEERTSQESDKKGLLGEVEGHTVESRTQEPCQEEAMPGEALTGLPAATPEELALGARRKRFLPKVRAGSDGEANKAEERESPTVSPRGPRKGLTPGSPGTPGRERRSPTQARKASMLEVPGAEEEPATGDLVSRSKDSGLDSEPAVDEGKQEALAKQRKAKDLLKAPQVIRKIRVEQFPDSSGSLKLWCQFFNIVSDSVLTWAKDQHPVGEVNRSAGDEGPAALAIVQASPTDCGVYRCTIQNEHGSASTDFCLSPEVLSGFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGHGLQKASRAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLLGRNYDVTIQGCKIQNMSREYCKIFAAEARAASGFGEVPEIIPLYLIYRPANNIPYATLEEDLGKPLQTYCSRQWGCAGAPAAASSSEALQKCQTFQHWLYQWTNGSFLVTDLTGADWKMTDVQIATKLRGYQGLKESCFPALLDQFASSHQCNTYCDMLGLKPLKGPEAAHPQAKAKGSKSPSAGRKGSQLSPQPQKKGLPSPQGSRKSAPSSRATLQASQAATVQLLGQPPVQDGSSKAQSMR", "length": 1680 }, "evidence": [ { "id": "F1N5U0", "url": "https://omabrowser.org/oma/group/F1N5U0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96L96-1", "protein_name": "Alpha-protein kinase 3", "gene_name": "ALPK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSRRAPSRGWGAGGRSGAGGDGEDDGPVWIPSPASRSYLLSVRPETSLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRSVSEDSDVRFTCIVTGYPEPEVTWYKDDTELDRYCGLPKYEITHQGNRHTLQLYRCREEDAAIYQASAQNSKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKLREIEQSWKHEKAVPGEVDTLRKLSPDRFQRKRRLSGAQAPGPSVPTREPEGGTLAAWQEGETETAQHSGLGLINSFASGEVTTNGEAAPENGEDGEHGLLTYICDAMELGPQRALKEESGAKKKKKDEESKQGLRKPELEKAAQSRRSSENCIPSSDEPDSCGTQGPVGVEQVQTQPRGRAARGPGSSGTDSTRKPASAVGTPDKAQKAPGPGPGQEVYFSLKDMYLENTQAVRPLGEEGPQTLSVRAPGESPKGKAPLRARSEGVPGAPGQPTHSLTPQPTRPFNRKRFAPPKPKGEATTDSKPISSLSQAPECGAQSLGKAPPQASVQVPTPPARRRHGTRDSTLQGQAGHRTPGEVLECQTTTAPTMSASSSSDVASIGVSTSGSQGIIEPMDMETQEDGRTSANQRTGSKKNVQADGKIQVDGRTRGDGTQTAQRTRADRKTQVDAGTQESKRPQSDRSAQKGMMTQGRAETQLETTQAGEKIQEDRKAQADKGTQEDRRMQGEKGMQGEKGTQSEGSAPTAMEGQSEQEVATSLGPPSRTPKLPPTAGPRAPLNIECFVQTPEGSCFPKKPGCLPRSEEAVVTASRNHEQTVLGPLSGNLMLPAQPPHEGSVEQVGGERCRGPQSSGPVEAKQEDSPFQCPKEERPGGVPCMDQGGCPLAGLSQEVPTMPSLPGTGLTASPKAGPCSTPTSQHGSTATFLPSEDQVLMSSAPTLHLGLGTPTQSHPPETMATSSEGACAQVPDVEGRTPGPRSCDPGLIDSLKNYLLLLLKLSSTETSGAGGESQVGAATGGLVPSATLTPTVEVAGLSPRTSRRILERVENNHLVQSAQTLLLSPCTSRRLTGLLDREVQAGRQALAAARGSWGPGPSSLTVPAIVVDEEDPGLASEGASEGEGEVSPEGPGLLGASQESSMAGRLGEAGGQAAPGQGPSAESIAQEPSQEEKFPGEALTGLPAATPEELALGARRKRFLPKVRAAGDGEATTPEERESPTVSPRGPRKSLVPGSPGTPGRERRSPTQGRKASMLEVPRAEEELAAGDLGPSPKAGGLDTEVALDEGKQETLAKPRKAKDLLKAPQVIRKIRVEQFPDASGSLKLWCQFFNILSDSVLTWAKDQRPVGEVGRSAGDEGPAALAIVQASPVDCGVYRCTIHNEHGSASTDFCLSPEVLSGFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGYGCGLRKASQAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLVGRNYDVTIQGCKIQNMSREYCKIFAAEARAAPGFGEVPEIIPLYLIYRPANNIPYATLEEDLGKPLESYCSREWGCAEAPTASGSSEAMQKCQTFQHWLYQWTNGSFLVTDLAGVDWKMTDVQIATKLRGYQGLKESCFPALLDRFASSHQCNAYCELLGLTPLKGPEAAHPQAKAKGSKSPSAGRKGSQLSPQPQKKGLPSPQGTRKSAPSSKATPQASEPVTTQLLGQPPTQEEGSKAQGMR", "length": 1705 }, "evidence": [ { "id": "F1N5U0", "url": "https://omabrowser.org/oma/group/F1N5U0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1N5U0", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1N5U0", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N5U0", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cardiac muscle cell development", "id": "GO:0055013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055013", "evidence": [ { "database": "UniProtKB", "id": "F1N5U0", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1497, "end_pos": 1499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1586, "end_pos": 1588, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", 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"id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377667" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2C1", "url": "https://www.uniprot.org/uniprotkb/F1N5X4", "locus": { "chromosome": "25", "start_pos": 2819855, "end_pos": 2818917, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001606", "url": "https://www.ensembl.org/id/ENSBTAG00000001606" } ] } } ], "crossref": [ { "id": "F1N5X4", "url": "https://alphafold.ebi.ac.uk/entry/F1N5X4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "104970118", "url": "https://www.ncbi.nlm.nih.gov/gene/104970118", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { 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"RefSeq", "categories": [ "Protein" ] }, { "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5X4-1", "url": "https://www.uniprot.org/uniprotkb/F1N5X4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERANSSSLEGFILMGVSDHPQLETIFFVGILFSYLLTLFGNSAIILLFNLDARLHTPMYFFLSNLSSLDLAFTTSSVPQMLTNLWGADKTISYGGCVTQLYVFLWLGATECILLVVMAFDRFVAVCRPLHYTTIMNPRLCWLLAAIAWLGGLGNSVVQSTFTLQLPLCGHRRVDSFLCEVPAMIKLACVDTSLNEAVLNSVCTFFTAVPLSVILISYCYIAQAVLKIRSAEGRRKAFNTCLSHLVVVLLFYGSAIYGYLLPAKTSKQDQGKFISLFYSVVTPMVNPLIYTLRNKEVKGALRRLLGKGREVS", "length": 312, "header": "tr|F1N5X4-1|F1N5X4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2C1 PE=3 SV=2 CANONICAL=F1N5X4-1" }, "isoforms": [ { "isoform_ac": "F1N5X4-1", "url": "https://www.uniprot.org/uniprotkb/F1N5X4/entry", "sequence": { "sequence": 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"https://www.genome.jp/dbget-bin/www_bget?bta:104970118", "resource": "KEGG Pathway" }, { "id": "R-BTA-381753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381753", "resource": "Reactome", "description": "Olfactory Signaling Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VTB0-1", "protein_name": "Olfactory receptor", "gene_name": "OR2C1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERANATSLEGFILMGVSDHPQLERVFFVVILFSYLLTLVGNGTIILLSSLDARLHTPMYFFLSNLSSLDLAFTTSSVPQMLVNLWGSDKTISYGGCVTQLYVFLWLGATECILLVVMAFDRYVAVCWPLHYTAVMNPRLCWLLAAIAWLGGLGNSGVQSTFTVQLPLCGNRRLDSFLCEVPAMIKMACGDTSLNEAVLNGVCTFFTAVPLSIILVSYCCIARAVLEIHSAEGRRKAFNTCLSHLLVVLLFYGSAIYGYLLPAKTSSQDQGKFISLFYSVVTPMANPLIYTLRNKEVKGALRRLLGKGREVS", "length": 312 }, "evidence": [ { "id": "F1N5X4", "url": "https://omabrowser.org/oma/group/F1N5X4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I037-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100766238", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEADSNSSSGSFILMGISDHPQLEMVFFVVILVSYLLTLLGNSTIILLSRLDARLHTPMYFFLSNLSSLDLAFTTSSVPQMLKNLWGPDKTISYGGCVTQLYVFLWLGATECILLVVMAFDRYVAVCRPLHYMSIMNPRLCWLLAAISWLGGLGNSVIQSTFTLQLPFCGHRKVDNFLCEVPAMIKLACGDTSLNEAVLNGVCTFFTAVPLSTILISYCFIARAVMKIRSVEGRRKAFNTCLSHLVVVFLFYGSAIYGYLLPAKSSNQDQGKFISLFYSVVTPMVNPLIYTLRNKEVKGALGRLLGKGTQAR", "length": 312 }, "evidence": [ { "id": "F1N5X4", "url": "https://omabrowser.org/oma/group/F1N5X4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V9S1-1", "protein_name": "Olfactory receptor", "gene_name": "Or2c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVGSNISSGSFILMGISNHPQLEIIFFVVILSSYLLTLVGNLTIILLSRLDARLHTPMYFFLSNLSSLDLAFTTSSVPQMLKNLWGPDKTISYGGCVTQLYVFLWLGATECILLVVMAFDRYVAVCRPLHYMTVMNPRLCWVLAAISWLGGLGNSVIQSTFTLQLPFCGHRKVDNFLCEVPAMIKLACGDTSLNEAVLNGVCTFFTAVPLSIILVSYCFIAQAVMKIRSVEGRRKAFNTCVSHLVVVFLFYGSAIYGYLLPAKSSNQDQGKFISLFYSVVTPMVNPLIYTLRNKEVKGALGRLLGKGRGAS", "length": 312 }, "evidence": [ { "id": "F1N5X4", "url": "https://omabrowser.org/oma/group/F1N5X4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95371-1", "protein_name": "Olfactory receptor 2C1", "gene_name": "OR2C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGVNDSSLQGFVLMGISDHPQLEMIFFIAILFSYLLTLLGNSTIILLSRLEARLHTPMYFFLSNLSSLDLAFATSSVPQMLINLWGPGKTISYGGCITQLYVFLWLGATECILLVVMAFDRYVAVCRPLRYTAIMNPQLCWLLAVIACLGGLGNSVIQSTFTLQLPLCGHRRVEGFLCEVPAMIKLACGDTSLNQAVLNGVCTFFTAVPLSIIVISYCLIAQAVLKIRSAEGRRKAFNTCLSHLLVVFLFYGSASYGYLLPAKNSKQDQGKFISLFYSLVTPMVNPLIYTLRNMEVKGALRRLLGKGREVG", "length": 312 }, "evidence": [ { "id": "F1N5X4", "url": "https://omabrowser.org/oma/group/F1N5X4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23275-1", "protein_name": "Olfactory receptor 2C1", "gene_name": "Or2c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVDSNSSSGSFILMGVSDHPHLEIIFFAVILASYLLTLVGNLTIILLSRLDARLHTPMYFFLSNLSSLDLAFTTSSVPQMLKNLWGPDKTISYGGCVTQLYVFLWLGATECILLVVMAFDRYVAVCRPLHYMTVMNPRLCWGLAAISWLGGLGNSVIQSTFTLQLPFCGHRKVDNFLCEVPAMIKLACGDTSLNEAVLNGVCTFFTVVPVSVILVSYCFIAQAVMKIRSVEGRRKAFNTCVSHLVVVFLFYGSAIYGYLLPAKSSNQSQGKFISLFYSVVTPMVNPLIYTLRNKEVKGALGRLLGKGRGAS", "length": 312 }, "evidence": [ { "id": "F1N5X4", "url": "https://omabrowser.org/oma/group/F1N5X4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "F1N5X4", "url": "https://www.uniprot.org/uniprotkb/F1N5X4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5X4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5X4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5X4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N617-1", "uniprot_ac": "F1N617", "uniprot_id": "F1N617_BOVIN", "mass": { "chemical_mass": 57947.0, "monoisotopic_mass": 57947.0 }, "refseq": { "ac": "XP_059741174", "name": "gap junction alpha-9 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741174" }, "gene_names": [ { "name": "GJA9", "type": "recommended", "evidence": [ { "id": "F1N617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N617" } ] }, { "name": "GJA9", "type": "synonym", "evidence": [ { "id": "XP_059741174", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741174" } ] } ], "protein_names": [ { "name": "Gap junction protein", "type": "recommended", "evidence": [ { "id": "F1N617", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N617/entry#names_and_taxonomy" } ] }, { "name": "gap junction alpha-9 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059741174", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741174" } ] } ], "function": [ { "annotation": "Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage. Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response.", "evidence": [ { "database": "UniProtKB", "id": "F1N617", "url": "https://www.uniprot.org/uniprotkb/F1N617#function" }, { "database": "UniProtKB", "id": "RU000630", "url": "https://www.uniprot.org/uniprotkb/RU000630#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N617", "url": "https://www.uniprot.org/uniprotkb/F1N617" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GJA9", "url": "https://www.uniprot.org/uniprotkb/F1N617", "locus": { "chromosome": "3", "start_pos": 107111231, "end_pos": 107106639, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030338", "url": "https://www.ensembl.org/id/ENSBTAG00000030338" } ] } } ], "crossref": [ { "id": "F1N617", "url": "https://alphafold.ebi.ac.uk/entry/F1N617", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030338", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030338", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100848695", "url": "https://www.ncbi.nlm.nih.gov/gene/100848695", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100848695", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848695", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWGQYKL", "url": "https://omabrowser.org/oma/group/LWGQYKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N617", "url": "https://www.orthodb.org/?gene=F1N617", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00029", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00029", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-190861", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-190861", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059741174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741174", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N617", "url": "https://www.uniprot.org/uniprotkb/F1N617", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N617-1", "url": "https://www.uniprot.org/uniprotkb/F1N617-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDWNFLGGILEEVHIHSTVIGKMWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDRAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEKQRQMKKEQLRGELEEAELETPGDRRRLEEELCQLEQRKVNKVPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCPNTIDCFVSRPTEKTIFLLFMQSIATVSLFLNVLEIFHLGFKKIKRGLWGQYKLKDEHNEFCTKSKQNLAKYQNTSANSLKRLSSVPDYSLLVDKQTHTAGYPSLNPSAFQTDPDNHIGNDDKGILDEQETLLSEMCTFSTACGHLQNISSSNKEDTHKLSGKEVNGNQLRGKRETDGKDSKRNHYFKGHCSSPGDAIELNNHVGQSPQTAFSLPANCTWKPKWPRATRGPSAESENQALPPKGYLKGQLRESTTRILPPSQGDFQPLDIPDTPDSSGGLSFESKLVRTCSNPTACTPTHLVSLTNNLIGRRAPTDLQI", "length": 513, "header": "tr|F1N617-1|F1N617_BOVIN Isoform 1 of Gap junction protein OS=Bos taurus OX=9913 GN=GJA9 PE=3 SV=2 CANONICAL=F1N617-1" }, "isoforms": [ { "isoform_ac": "F1N617-1", "url": "https://www.uniprot.org/uniprotkb/F1N617/entry", "sequence": { "sequence": "MGDWNFLGGILEEVHIHSTVIGKMWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDRAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEKQRQMKKEQLRGELEEAELETPGDRRRLEEELCQLEQRKVNKVPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCPNTIDCFVSRPTEKTIFLLFMQSIATVSLFLNVLEIFHLGFKKIKRGLWGQYKLKDEHNEFCTKSKQNLAKYQNTSANSLKRLSSVPDYSLLVDKQTHTAGYPSLNPSAFQTDPDNHIGNDDKGILDEQETLLSEMCTFSTACGHLQNISSSNKEDTHKLSGKEVNGNQLRGKRETDGKDSKRNHYFKGHCSSPGDAIELNNHVGQSPQTAFSLPANCTWKPKWPRATRGPSAESENQALPPKGYLKGQLRESTTRILPPSQGDFQPLDIPDTPDSSGGLSFESKLVRTCSNPTACTPTHLVSLTNNLIGRRAPTDLQI", "length": 513, "header": "tr|F1N617-1|F1N617_BOVIN Isoform 1 of Gap junction protein OS=Bos taurus OX=9913 GN=GJA9 PE=3 SV=2 CANONICAL=F1N617-1" }, "locus": { "chromosome": "3", "start_pos": 107110686, "end_pos": 107109148, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042836.5", "url": "https://www.ensembl.org/id/ENSBTAT00000042836.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040446.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040446.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100848695", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848695", "resource": "KEGG Pathway" }, { "id": "R-BTA-190861", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-190861", "resource": "Reactome", "description": "Gap junction assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SV25-1", "protein_name": "Gap junction protein", "gene_name": "GJA9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDWNFLGGILEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEKERQVKKAQLRGELEGVELEMPGDRKRLEQELYQLEQWKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLYKCQGHPCPNIIDCFVSRPTEKTIFLLFMQSIATVSVFLNVLEICHLGFKKIKRGIWGQYKLKDKQNEFCTNKSKQNLAKYQNTSANSLKRLSSAPDYSLLVEKQTHRAVYPSLNSSVYQTDPDSHRGNDERGISNEQETVLSNKMCTLSTACGHLQNVSSSNKEDTHKISGKEVNGNQVRGKRESDSEDSKRNHYPRGYRSIPGDAIDLNDHTGQSPQTAFSLPANCTWKPKWFCATWGPSAENENQALPPKGNLKGQLRENPVRTLPPSPGDFQPPDIPDTPDSLGVLSFESELVRTCDNPAASPPQHSVSLTNNLISRRAPTDLQI", "length": 515 }, "evidence": [ { "id": "F1N617", "url": "https://omabrowser.org/oma/group/F1N617/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P57773-1", "protein_name": "Gap junction alpha-9 protein", "gene_name": "GJA9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKRGLWGKYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSLNSSSVFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFGKELNGNQLMEKRETEGKDSKRNYYSRGHRSIPGVAIDGENNMRQSPQTVFSLPANCDWKPRWLRATWGSSTEHENRGSPPKGNLKGQFRKGTVRTLPPSQGDSQSLDIPNTADSLGGLSFEPGLVRTCNNPVCPPNHVVSLTNNLIGRRVPTDLQI", "length": 515 }, "evidence": [ { "id": "F1N617", "url": "https://omabrowser.org/oma/group/F1N617/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "F1N617", "url": "https://www.uniprot.org/uniprotkb/F1N617" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "F1N617", "url": "https://www.uniprot.org/uniprotkb/F1N617" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "F1N617", "url": "https://www.uniprot.org/uniprotkb/F1N617" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"SM01089", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 233, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 411, "end_pos": 413 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N633-1", "uniprot_ac": "F1N633", "uniprot_id": "F1N633_BOVIN", "mass": { "chemical_mass": 47665.0, "monoisotopic_mass": 47665.0 }, "refseq": { "ac": "XP_002688364", "name": "transmembrane protease serine 11E", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688364" }, "gene_names": [ { "name": "TMPRSS11E", "type": "recommended", "evidence": [ { "id": "F1N633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N633" } ] }, { "name": "TMPRSS11E", "type": "synonym", "evidence": [ { "id": "XP_002688364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688364" } ] } ], "protein_names": [ { "name": "Transmembrane protease serine", "type": "recommended", "evidence": [ { "id": "F1N633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N633/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.-", "type": "synonym", "evidence": [ { "id": "F1N633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N633/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protease serine 11E", "type": "synonym", "evidence": [ { "id": "XP_002688364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688364" } ] } ], "function": [ { "annotation": "Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position.", "evidence": [ { "database": "UniProtKB", "id": "F1N633", "url": "https://www.uniprot.org/uniprotkb/F1N633#function" }, { "database": "UniProtKB", "id": "ARBA00053618", "url": "https://www.uniprot.org/uniprotkb/ARBA00053618#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N633", "url": "https://www.uniprot.org/uniprotkb/F1N633" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMPRSS11E", "url": "https://www.uniprot.org/uniprotkb/F1N633", "locus": { "chromosome": "6", "start_pos": 83956053, "end_pos": 84012727, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038520", "url": "https://www.ensembl.org/id/ENSBTAG00000038520" } ] } } ], "crossref": [ { "id": "F1N633", "url": "https://alphafold.ebi.ac.uk/entry/F1N633", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038520", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100335739", "url": "https://www.ncbi.nlm.nih.gov/gene/100335739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100335739", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100335739", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002688364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688364", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N633", "url": "https://www.uniprot.org/uniprotkb/F1N633", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N633-1", "url": "https://www.uniprot.org/uniprotkb/F1N633-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRSSVVRARKRACLEPWVVGLITFISLIVLAVCIGLIIHYARYNQKKTYNYYSTLSFTSNKVYDEFGKEASENFTKMSQKIESMVKNAFHKSSLRGKFVKSHIIKFSQEEHGVLAHMLLIFRFPSTEDPETINKIIQHVLHEKLQDAVGPPKLDPESVEIKKINKTETDNFLNNCCGTRRNKTPGQSLRIVGGTEVQEGEWPWQTSLQWDGIHRCGATLINDTWLVSAAHCFRTYKDPARWTASFGVTIYPPKMRRALRRIIVHEKYKYPSHDYDISVLELSRPVPYTNAVHKICLPDASHEFRPGDEMFVTGFGALQNDGSSQNHLRQVQVDLIDAKICNAPQAYNNAITPTMLCAGSLKGNKDACQGDSGGPLVSPDARDIWYLAGIVSWGDECGQPNKPGVYTKVTTFRDWITSKTGV", "length": 422, "header": "tr|F1N633-1|F1N633_BOVIN Isoform 1 of Transmembrane protease serine OS=Bos taurus OX=9913 GN=TMPRSS11E PE=3 SV=4 CANONICAL=F1N633-1" }, "isoforms": [ { "isoform_ac": "F1N633-1", "url": "https://www.uniprot.org/uniprotkb/F1N633/entry", "sequence": { "sequence": 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spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5#function" }, { "database": "UniProtKB", "id": "ARBA00045974", "url": "https://www.uniprot.org/uniprotkb/ARBA00045974#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EFTUD2", "url": "https://www.uniprot.org/uniprotkb/F1N6D5", "locus": { "chromosome": "19", "start_pos": 44567288, "end_pos": 44603719, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013526", "url": "https://www.ensembl.org/id/ENSBTAG00000013526" } ] } } ], "crossref": [ { "id": "F1N6D5", "url": "https://alphafold.ebi.ac.uk/entry/F1N6D5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013526", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013526", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04098", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04098", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16264", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16264", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N6D5", "url": "https://www.orthodb.org/?gene=F1N6D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42908", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42908", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42908:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42908:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6D5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6D5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDLEEMLYVICHVHFTDGTMDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEVDEDEDDDDVGDHDEDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 992, "header": "tr|F1N6D5-1|F1N6D5_BOVIN Isoform 1 of 116 kDa U5 small nuclear ribonucleoprotein component OS=Bos taurus OX=9913 GN=EFTUD2 PE=4 SV=2 CANONICAL=F1N6D5-1" }, "isoforms": [ { "isoform_ac": "F1N6D5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6D5/entry", "sequence": { "sequence": "MSDLEEMLYVICHVHFTDGTMDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEVDEDEDDDDVGDHDEDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM", "length": 992, "header": "tr|F1N6D5-1|F1N6D5_BOVIN Isoform 1 of 116 kDa U5 small nuclear ribonucleoprotein component OS=Bos taurus OX=9913 GN=EFTUD2 PE=4 SV=2 CANONICAL=F1N6D5-1" }, "locus": { "chromosome": "19", "start_pos": 44603520, "end_pos": 44567661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017986.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017986.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017986.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017986.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1N6D5", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6D5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 992, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6D5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6D5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N6D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6D5" }, { "id": "PS51722", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51722" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tr-type G", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 429, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 631, "end_pos": 633 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6F5-1", "uniprot_ac": "F1N6F5", "uniprot_id": "F1N6F5_BOVIN", "mass": { "chemical_mass": 60456.0, "monoisotopic_mass": 60456.0 }, "refseq": { "ac": "XP_002685263", "name": "cytochrome P450 27C1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685263" }, "gene_names": [ { "name": "CYP27C1", "type": "recommended", "evidence": [ { "id": "F1N6F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ] }, { "name": "CYP27C1", "type": "synonym", "evidence": [ { "id": "XP_002685263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685263" } ] } ], "protein_names": [ { "name": "Cytochrome P450 family 27 subfamily C member 1", "type": "synonym", "evidence": [ { "id": "F1N6F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6F5/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 27C1", "type": "synonym", "evidence": [ { "id": "XP_002685263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685263" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CYP27C1", "url": "https://www.uniprot.org/uniprotkb/F1N6F5", "locus": { "chromosome": "2", "start_pos": 5319519, "end_pos": 5297503, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038275", "url": "https://www.ensembl.org/id/ENSBTAG00000038275" } ] } } ], "crossref": [ { "id": "F1N6F5", "url": "https://alphafold.ebi.ac.uk/entry/F1N6F5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038275", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617338", "url": "https://www.ncbi.nlm.nih.gov/gene/617338", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617338", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617338", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIHLVMI", "url": "https://omabrowser.org/oma/group/EIHLVMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6F5", "url": "https://www.orthodb.org/?gene=F1N6F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24279", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24279", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24279:SF122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24279:SF122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002685263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6F5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6F5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLARILKARPSPAAGRTGLLGGWDAGQPRLASSGLSARARAEDKGAGRPGASQAGGRAEGPRSLAAMPGPRTLANLVEFFGKDGFSRIHEIQQKHTREYGKIFKSHFGPQFVVSVADRDLVAQVLRAEGASPQRANMGSWQEYRDLRGRSTGLISAEGEQWLKMRSVLRQRILKPKDVAIFAGEINQVIADLIKRIYFLKSQAEDGDTVTNINDLFFKYSMEGVATILYESRLGCLGNSIPQLTADYIEALALMFCTFKTSMYAGAIPRWLRLLIPKPWQEFCRSWDGLFEFSQIHVDNKLRDIRCQMERGERVRGGLLTYLFLSQELTLEEIYANMTEMLLAGVDTTSFTLSWAVYLLARHPEVQQALYREIVRNLGERHVPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLIVGGYLIPRGTQLALCHYATSYEDENFPRAKEFRPERWLRQGNLRRVDNFGSIPFGYGARSCIGRRIAELEIHLLVIQLLQHFEIKTSPWTKTVHAKTHGLLMPGEPIHVRFVNRK", "length": 537, "header": "tr|F1N6F5-1|F1N6F5_BOVIN Isoform 1 of Cytochrome P450 family 27 subfamily C member 1 OS=Bos taurus OX=9913 GN=CYP27C1 PE=3 SV=2 CANONICAL=F1N6F5-1" }, "isoforms": [ { "isoform_ac": "F1N6F5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6F5/entry", "sequence": { "sequence": "MALLARILKARPSPAAGRTGLLGGWDAGQPRLASSGLSARARAEDKGAGRPGASQAGGRAEGPRSLAAMPGPRTLANLVEFFGKDGFSRIHEIQQKHTREYGKIFKSHFGPQFVVSVADRDLVAQVLRAEGASPQRANMGSWQEYRDLRGRSTGLISAEGEQWLKMRSVLRQRILKPKDVAIFAGEINQVIADLIKRIYFLKSQAEDGDTVTNINDLFFKYSMEGVATILYESRLGCLGNSIPQLTADYIEALALMFCTFKTSMYAGAIPRWLRLLIPKPWQEFCRSWDGLFEFSQIHVDNKLRDIRCQMERGERVRGGLLTYLFLSQELTLEEIYANMTEMLLAGVDTTSFTLSWAVYLLARHPEVQQALYREIVRNLGERHVPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLIVGGYLIPRGTQLALCHYATSYEDENFPRAKEFRPERWLRQGNLRRVDNFGSIPFGYGARSCIGRRIAELEIHLLVIQLLQHFEIKTSPWTKTVHAKTHGLLMPGEPIHVRFVNRK", "length": 537, "header": "tr|F1N6F5-1|F1N6F5_BOVIN Isoform 1 of Cytochrome P450 family 27 subfamily C member 1 OS=Bos taurus OX=9913 GN=CYP27C1 PE=3 SV=2 CANONICAL=F1N6F5-1" }, "locus": { "chromosome": "2", "start_pos": 5318750, "end_pos": 5297702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056152.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056152.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052365.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052365.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617338", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617338", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A8WGA0-1", "protein_name": "Cytochrome P450 27C1", "gene_name": "cyp27c1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALQSTILHMARKNLLQESCRQLLIQTHGLHKSVASGSLEIAAHSQADLKEESAVSPAEEVQKAARVKSLKEMPGPSTVANLLEFFYRDGFSRIHEIQMEHAKKYGKIFKSRFGPQFVVSIADRDMVAQVLRSESATPQRGNMESWKEYRDLRGRSTGLISAEGDEWLKMRSVLRQLIMRPRDVAVFSSDVNDVVADLVKRVKTLRSQQDDSQTVLNINDLFFKYAMEGVATILYETRLGCLENEIPKMSQEYITALHLMFSSFKTTMYAGAIPKWLRPIIPKPWEEFCSSWDGLFKFSQIHVDKRLSEIKKQMEKSEEIKGGLLTHMLVTREMNLEEIYANMTEMLLAGVDTTSFTLSWSTYLLARHPTIQQQIFEEVDRVLGGRVPTGEDVPYLPLIRGLVKETLRLFPVLPGNGRVTHDDLIVGGYLIPKGTQLALCHYSTSMDEENFPRPEEFRPDRWIRKDASDRVDNFGSIPFGYGIRSCIGRRIAELEMHLALTQLLQNFHIEVSPQTTEVHAKTHGLLCPGASINLRFTDRK", "length": 540 }, "evidence": [ { "id": "F1N6F5", "url": "https://omabrowser.org/oma/group/F1N6F5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4G0S4-2", "protein_name": "Cytochrome P450 27C1", "gene_name": "CYP27C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQTSAMALLARILRAGLRPAPERGGLLGGGAPRRPQPAGARLPAGARAEDKGAGRPGSPPGGGRAEGPRSLAAMPGPRTLANLAEFFCRDGFSRIHEIQQKHTREYGKIFKSHFGPQFVVSIADRDMVAQVLRAEGAAPQRANMESWREYRDLRGRATGLISAEGEQWLKMRSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGVATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFCRSWDGLFKFSQIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQTNAVHAKTHGLLTPGGPIHVRFVNRK", "length": 542 }, "evidence": [ { "id": "F1N6F5", "url": "https://omabrowser.org/oma/group/F1N6F5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "retinoic acid binding", "id": "GO:0001972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001972", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "all-trans retinol 3,4-desaturase activity", "id": "GO:0061896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061896", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "all-trans retinal 3,4-desaturase activity", "id": "GO:0061897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061897", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "all-trans retinoic acid 3,4-desaturase activity", "id": "GO:0061898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061898", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "all-trans-retinol binding", "id": "GO:1904768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904768", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1N6F5", "url": "https://www.uniprot.org/uniprotkb/F1N6F5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6F5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 537, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6F5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6F5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6K2-1", "uniprot_ac": "F1N6K2", "uniprot_id": "F1N6K2_BOVIN", "mass": { "chemical_mass": 37006.0, "monoisotopic_mass": 37006.0 }, "refseq": { "ac": "XP_002690724", "name": "olfactory receptor 11H12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690724" }, "gene_names": [ { "name": "OR11G29", "type": "recommended", "evidence": [ { "id": "F1N6K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6K2" } ] }, { "name": "OR11G29", "type": "synonym", "evidence": [ { "id": "XP_002690724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690724" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "F1N6K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6K2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 11H12", "type": "synonym", "evidence": [ { "id": "XP_002690724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690724" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1N6K2", "url": "https://www.uniprot.org/uniprotkb/F1N6K2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6K2", "url": "https://www.uniprot.org/uniprotkb/F1N6K2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR11G29", "url": "https://www.uniprot.org/uniprotkb/F1N6K2", "locus": { "chromosome": "10", "start_pos": 27146096, "end_pos": 27147442, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038672", "url": "https://www.ensembl.org/id/ENSBTAG00000038672" } ] } } ], "crossref": [ { "id": "F1N6K2", "url": "https://alphafold.ebi.ac.uk/entry/F1N6K2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "784455", "url": "https://www.ncbi.nlm.nih.gov/gene/784455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MTGQRCF", "url": "https://omabrowser.org/oma/group/MTGQRCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { 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biosynthetic process", "id": "GO:0006228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006228", "evidence": [ { "database": "UniProtKB", "id": "F1N6T4", "url": "https://www.uniprot.org/uniprotkb/F1N6T4" } ], "pmid": "" }, { "name": "CTP biosynthetic process", "id": "GO:0006241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006241", "evidence": [ { "database": "UniProtKB", "id": "F1N6T4", "url": "https://www.uniprot.org/uniprotkb/F1N6T4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18113", "name": "", "equation": "a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFD0-1", "Q3T0Q4-1", "A0AAF6ZEA8-1", "P00570-1", "Q2KIW9-1", "A0A3Q1LVZ0-1", "P52175-1", "Q0VCP1-1", "A0AAA9SPL6-1", "F1N2W6-1", "F1N6T4-1", "F1MUF5-1", "A0AAA9TUI5-1" ], "evidence": [ { "id": "18113", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18113" } ] }, { "id": "25098", "name": "", "equation": "UDP + ATP = UTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "P00570-1", "Q2KIW9-1", "F1MUF5-1", "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1", "F1N6T4-1" ], "evidence": [ { "id": "25098", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25098" } ] }, { "id": "25237", "name": "", "equation": "CDP + ATP = CTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "F1MUF5-1", "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1", "F1N6T4-1" ], "evidence": [ { "id": "25237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25237" } ] }, { "id": "27678", "name": "", "equation": "dCDP + ATP = dCTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "F1MUF5-1", "P52175-1", "F1N6T4-1" ], "evidence": [ { "id": "27678", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27678" } ] }, { "id": "27682", "name": "", "equation": "dTDP + ATP = dTTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "F1MUF5-1", "P52175-1", "Q3T0Q4-1", "F1N6T4-1" ], "evidence": [ { "id": "27682", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27682" } ] }, { "id": "27686", "name": "", "equation": "GDP + ATP = GTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "P00570-1", "Q2KIW9-1", "F1MUF5-1", "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1", "F1N6T4-1" ], "evidence": [ { "id": "27686", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27686" } ] }, { "id": "27690", "name": "", "equation": "dGDP + ATP = dGTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "P00570-1", "Q2KIW9-1", "F1MUF5-1", "F1N6T4-1" ], "evidence": [ { "id": "27690", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27690" } ] }, { "id": "38695", "name": "", "equation": "a cardiolipin(in) = a cardiolipin(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N6T4-1" ], "evidence": [ { "id": "38695", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38695" } ] }, { "id": "44640", "name": "", "equation": "a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TUI5-1", "A4IFD0-1", "Q3T0Q4-1", "A0AAF6ZEA8-1", "P00570-1", "P52175-1", "Q2KIW9-1", "A0A3Q1LVZ0-1", "Q0VCP1-1", "A0AAA9SPL6-1", "F1N2W6-1", "F1N6T4-1" ], "evidence": [ { "id": "44640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44640" } ] }, { "id": "R-BTA-482804", "name": "(d)NDP + ATP <=> (d)NTP + ADP (NME4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N6T4-1" ], "evidence": [ { "id": "R-BTA-482804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-482804" } ] }, { "id": "R-BTA-482812", "name": "(d)NTP + ADP <=> (d)NDP + ATP (NME4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N6T4-1" ], "evidence": [ { "id": "R-BTA-482812", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-482812" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LVZ0", "gene_name": "AK4", "activity": [ { "ec_number": "2.7.4.10", "activity": "a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] }, { "ec_number": "2.7.4.10", "activity": "", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] } ] }, { "uniprot_ac": "A0AAA9SPL6", "gene_name": "AK8", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] } ] }, { "uniprot_ac": "A0AAA9TUI5", "gene_name": "NME6", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0AAA9TUI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0AAA9TUI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ] } ] }, { "uniprot_ac": "A0AAF6ZEA8", "gene_name": "AK4", "activity": [ { "ec_number": "2.7.4.10", "activity": "a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] }, { "ec_number": "2.7.4.10", "activity": "", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] } ] }, { "uniprot_ac": "A4IFD0", "gene_name": "Ak5", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] } ] }, { "uniprot_ac": "F1MUF5", "gene_name": "AK9", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] }, { "ec_number": "2.7.4.4", "activity": "a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] }, { "ec_number": "2.7.4.4", "activity": "", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] } ] }, { "uniprot_ac": "F1N2W6", "gene_name": "CMPK2", "activity": [ { "ec_number": "2.7.4.14", "activity": "UMP + ATP = UDP + ADP.", "evidence": [ { "id": "F1N2W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W6" } ] }, { "ec_number": "2.7.4.14", "activity": "", "evidence": [ { "id": "F1N2W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W6" } ] } ] }, { "uniprot_ac": "F1N6T4", "gene_name": "NME4", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "F1N6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6T4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "F1N6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6T4" } ] } ] }, { "uniprot_ac": "P00570", "gene_name": "AK1", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "P00570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00570" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P00570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00570" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "P00570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00570" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P00570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00570" } ] }, { "ec_number": "2.7.4.4", "activity": "a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "P00570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00570" } ] }, { "ec_number": "2.7.4.4", "activity": "", "evidence": [ { "id": "P00570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00570" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "Q0VCP1", "gene_name": "AK4", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "Q0VCP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCP1" } ] }, { "ec_number": "2.7.4.4", "activity": "a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "Q0VCP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCP1" } ] }, { "ec_number": "2.7.4.4", "activity": "", "evidence": [ { "id": "Q0VCP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCP1" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "Q0VCP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCP1" } ] } ] }, { "uniprot_ac": "Q2KIW9", "gene_name": "CMPK1", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6V7-1", "uniprot_ac": "F1N6V7", "uniprot_id": "F1N6V7_BOVIN", "mass": { "chemical_mass": 67147.0, "monoisotopic_mass": 67147.0 }, "refseq": { "ac": "XP_059734605", "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734605" }, "gene_names": [ { "name": "ST6GALNAC1", "type": "recommended", "evidence": [ { "id": "F1N6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ] }, { "name": "ST6GALNAC1", "type": "synonym", "evidence": [ { "id": "XP_059734605", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734605" } ] } ], "protein_names": [ { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase", "type": "recommended", "evidence": [ { "id": "F1N6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6V7/entry#names_and_taxonomy" } ] }, { "name": "2.4.3.3", "type": "synonym", "evidence": [ { "id": "F1N6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6V7/entry#names_and_taxonomy" } ] }, { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059734605", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734605" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6V7", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ST6GALNAC1", "url": "https://www.uniprot.org/uniprotkb/F1N6V7", "locus": { "chromosome": "19", "start_pos": 55138752, "end_pos": 55120932, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001998", "url": "https://www.ensembl.org/id/ENSBTAG00000001998" } ] } } ], "crossref": [ { "id": "F1N6V7", "url": "https://alphafold.ebi.ac.uk/entry/F1N6V7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001998", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001998", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618655", "url": "https://www.ncbi.nlm.nih.gov/gene/618655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WDFEEQY", "url": "https://omabrowser.org/oma/group/WDFEEQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6V7", "url": "https://www.orthodb.org/?gene=F1N6V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45941:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45941:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059734605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734605", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11136", "url": "https://www.rhea-db.org/rhea/11136", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81643", "url": "https://www.rhea-db.org/rhea/81643", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81659", "url": "https://www.rhea-db.org/rhea/81659", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N6V7", "url": "https://www.uniprot.org/uniprotkb/F1N6V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6V7-1", "url": "https://www.uniprot.org/uniprotkb/F1N6V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPCPRRLCRLDQTVRGLLLLAVLIFFLFTLPSFIKEPNTKPSRNEHQQNIKERSLELLQNATSQAPTPRRRATTHVESVQGTRTRDTHPKATTLTADQRRRVQTSKARAEEPGRVPTPIGKAAPQTQASKDTRADTLPPMAGGGGVASSRTEAPSLNSQNPRMTKGSGDRKARPTGPRAVPTKLRDSPATAAKTLLPKHRAGAQTPGGGGQEGKRARGASPAAAPSQDRAQPTRSSAPLQSPATQRSQKLKATNFKSEPQWDFEEEYSLEVGGLQTTCPDSVKIKASKSPWLQTLFLPNLTLFLDSGHFNQSEWDRLEHFAPPFGFMELNFSLVQKVVARFPPVPQQQLLLASLPTGSSQCISCAVVGNGGILNNSHVGPEIDSHDYVFRLSGAIIKGYEHDVGTRTSFYGFTAFSLTQSLLILGSRGFPHAPLGQDVRYLHFLEGTRDYEWLEALLLNRTLTSRNLSWFRRRPQEAFQEALQLDRYLLLHPDLLRYMKNRFLRSKTLNTAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDKSWKRTIFYTNHDFKLERALWKRLHDEGIIRLYQRPITSKPTI", "length": 598, "header": "tr|F1N6V7-1|F1N6V7_BOVIN Isoform 1 of alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase OS=Bos taurus OX=9913 GN=ST6GALNAC1 PE=3 SV=3 CANONICAL=F1N6V7-1" }, "isoforms": [ { "isoform_ac": "F1N6V7-1", "url": "https://www.uniprot.org/uniprotkb/F1N6V7/entry", "sequence": { "sequence": "MRPCPRRLCRLDQTVRGLLLLAVLIFFLFTLPSFIKEPNTKPSRNEHQQNIKERSLELLQNATSQAPTPRRRATTHVESVQGTRTRDTHPKATTLTADQRRRVQTSKARAEEPGRVPTPIGKAAPQTQASKDTRADTLPPMAGGGGVASSRTEAPSLNSQNPRMTKGSGDRKARPTGPRAVPTKLRDSPATAAKTLLPKHRAGAQTPGGGGQEGKRARGASPAAAPSQDRAQPTRSSAPLQSPATQRSQKLKATNFKSEPQWDFEEEYSLEVGGLQTTCPDSVKIKASKSPWLQTLFLPNLTLFLDSGHFNQSEWDRLEHFAPPFGFMELNFSLVQKVVARFPPVPQQQLLLASLPTGSSQCISCAVVGNGGILNNSHVGPEIDSHDYVFRLSGAIIKGYEHDVGTRTSFYGFTAFSLTQSLLILGSRGFPHAPLGQDVRYLHFLEGTRDYEWLEALLLNRTLTSRNLSWFRRRPQEAFQEALQLDRYLLLHPDLLRYMKNRFLRSKTLNTAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDKSWKRTIFYTNHDFKLERALWKRLHDEGIIRLYQRPITSKPTI", "length": 598, "header": "tr|F1N6V7-1|F1N6V7_BOVIN Isoform 1 of alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase OS=Bos taurus OX=9913 GN=ST6GALNAC1 PE=3 SV=3 CANONICAL=F1N6V7-1" }, "locus": { "chromosome": "19", "start_pos": 55137888, "end_pos": 55121131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034693.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034693.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034579.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034579.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RZ66-1", "protein_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase", "gene_name": "ST6GALNAC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPCPRRLGRLGHAVQWLLLSAVLICLFALPSFFKGSNTKPIRRQHAENIKERSPELLQKNSSRATPTARRTATHVESSQGPSTKATHPKATTHVAGKGKGAEASKASAEEPSRAPSAARTAALETQDSKDATVDTPPPKGQGRGMTSGRTEAPSLKAQDTRMTEGPGDKNSRLMAPRTVPTKPQGHSRATARMPLPVSQGVRAPAGVRLTGATTAAVPPEKSTQATPSSAPPQSPTTQRAQRLQAANFKSEPQWDFEEEYSLDVGGLQSTCPDSVKIKASRSPWLQKLFLPNLTLFLDSRHFNLSEWVRLEHFAPPFGFMELNFSLVQKVVTRFPPVPQQQLLLAALPSGSSQCIRCAVVGNGGILNNSHMGREIDGHDYVFRLSGAVIKGYEQDVGTRTSFYGFTAFSLTQSLLILGSRGFQHAPLGKDVRYLHFLEGTRDYEWLEALLLNQTLVKKSLFWFRHRPQEAFQEALQMDRYLLLHPDLLRYMKNRFLRSKTLNTAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDKSWKRTIFYINHDFRLERTLWKRLHDEGIIRLYQRPGTPTPTI", "length": 591 }, "evidence": [ { "id": "F1N6V7", "url": "https://omabrowser.org/oma/group/F1N6V7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NSC7-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1", "gene_name": "ST6GALNAC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTVSEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPFQSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPNLTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN", "length": 600 }, "evidence": [ { "id": "F1N6V7", "url": "https://omabrowser.org/oma/group/F1N6V7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZ39-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1", "gene_name": "St6galnac1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRYCRGLSQRQAFLLLTVLALLFILLFVVKDPRAKDSRCQFIWKNDASAQENQQKAEPQVPIMTLSPRVHNKETTSVSSKDLKKQEREAVQGEQAEGKEKRKLETIRPAPENPQSKAEPAAKTPVSEHLDKLPRAPGALSTRKTPMATGAVPAKKKVVQATKSPASSPHPTTRRRQRLKASEFKSEPRWDFEEEYSLDMSSLQTNCSASVKIKASKSPWLQNIFLPNITLFLDSGRFTQSEWNRLEHFAPPFGFMELNQSLVQKVVTRFPPVRQQQLLLASLPTGYSKCITCAVVGNGGILNDSRVGREIDSHDYVFRLSGAVIKGYEQDVGTRTSFYGFTAFSLTQSILILGRRGFQHVPLGKDVRYLHFLEGTRDYEWLEAMFLNQTLAKTHLSWFRHRPQEAFRNALDLDRYLLLHPDFLRYMKNRFLRSKTLDTAHWRIYRPTTGALLLLTALHLCDKVSAYGFITEGHQRFSDHYYDTSWKRLIFYINHDFRLERMVWKRLHDEGIIWLYQRPQSDKAKN", "length": 526 }, "evidence": [ { "id": "F1N6V7", "url": "https://omabrowser.org/oma/group/F1N6V7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1N6V7", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "F1N6V7", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ], "pmid": "" }, { "name": "oligosaccharide biosynthetic process", "id": "GO:0009312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009312", "evidence": [ { "database": "UniProtKB", "id": "F1N6V7", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ], "pmid": "" }, { "name": "host-mediated modulation of intestinal microbiota composition", "id": "GO:0048874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048874", "evidence": [ { "database": "UniProtKB", "id": "F1N6V7", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "id": "GO:0001665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001665", "evidence": [ { "database": "UniProtKB", "id": "F1N6V7", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11136", "name": "", "equation": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N6V7-1", "A0A3Q1LRX1-1" ], "evidence": [ { "id": "11136", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11136" } ] }, { "id": "81643", "name": "", "equation": "a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-[N-acetyl-alpha-neuraminosyl-(2->6)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRX1-1", "F1N6V7-1" ], "evidence": [ { "id": "81643", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81643" } ] }, { "id": "81659", "name": "", "equation": "a 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRX1-1", "F1N6V7-1" ], "evidence": [ { "id": "81659", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81659" } ] }, { "id": "R-BTA-4084980", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-4086301" ], "output_participant_list": [ "R-ALL-4086341" ], "enzyme_list": [ "F1N6V7-1", "G3N3B2-1", "A0A3Q1LRX1-1" ], "evidence": [ { "id": "R-BTA-4084980", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4084980" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-4086301", "participant_name": "GalNAc-R [Golgi lumen]", "crossref": [ { "id": "21507", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-4086341", "participant_name": "Neu5Ac-2,6-GalNAc-R [Golgi lumen]", "crossref": [ { "id": "62634", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LRX1", "gene_name": "ST6GALNAC2", "activity": [ { "ec_number": "2.4.3.3", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0A3Q1LRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRX1" } ] }, { "ec_number": "2.4.3.3", "activity": "", "evidence": [ { "id": "A0A3Q1LRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRX1" } ] } ] }, { "uniprot_ac": "F1N6V7", "gene_name": "ST6GALNAC1", "activity": [ { "ec_number": "2.4.3.3", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "F1N6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ] }, { "ec_number": "2.4.3.3", "activity": "", "evidence": [ { "id": "F1N6V7", "database": "UniProtKB", "url": 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"Ensembl Gene", "id": "ENSBTAG00000016980", "url": "https://www.ensembl.org/id/ENSBTAG00000016980" } ] } } ], "crossref": [ { "id": "F1N6W2", "url": "https://alphafold.ebi.ac.uk/entry/F1N6W2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016980", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016980", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01921", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01921", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535676", "url": "https://www.ncbi.nlm.nih.gov/gene/535676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N6W2", "url": "https://www.orthodb.org/?gene=F1N6W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45843", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45843:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45843:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059745765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N6W2", "url": "https://www.uniprot.org/uniprotkb/F1N6W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6W2-1", "url": "https://www.uniprot.org/uniprotkb/F1N6W2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPATAQFISGPWLKSLFLRSNLSPPLVLASRVAACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTGRGGESVFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLDGVHTVFGEVTEGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPEPTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPENVLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFKMDNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPSNLVLKDKVKPKQDAKYELVLDEQAEDSKAGHSHTSKKHKKKTRHCSEEKEDEDYMPIKNTNQDIYREMGFGHYEEEESCWEKQKSEKRDRPQNRSRSRSRERDGHYSNSHKSKYQADPYERERSKKRDRSRSPRKSKDKEKSKYR", "length": 503, "header": "tr|F1N6W2-1|F1N6W2_BOVIN Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Bos taurus OX=9913 GN=PPIL4 PE=3 SV=2 CANONICAL=F1N6W2-1" }, "isoforms": [ { "isoform_ac": "F1N6W2-1", "url": "https://www.uniprot.org/uniprotkb/F1N6W2/entry", "sequence": { "sequence": "MVPATAQFISGPWLKSLFLRSNLSPPLVLASRVAACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTGRGGESVFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLDGVHTVFGEVTEGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPEPTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPENVLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFKMDNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPSNLVLKDKVKPKQDAKYELVLDEQAEDSKAGHSHTSKKHKKKTRHCSEEKEDEDYMPIKNTNQDIYREMGFGHYEEEESCWEKQKSEKRDRPQNRSRSRSRERDGHYSNSHKSKYQADPYERERSKKRDRSRSPRKSKDKEKSKYR", "length": 503, "header": "tr|F1N6W2-1|F1N6W2_BOVIN Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Bos taurus OX=9913 GN=PPIL4 PE=3 SV=2 CANONICAL=F1N6W2-1" }, "locus": { "chromosome": "9", "start_pos": 86782106, "end_pos": 86744986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022582.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022582.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022582.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022582.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1N6W2", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "F1N6W2", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N6W2", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N6W2", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N6W2", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M4A4-1", "P18203-1", "Q5BIN5-1", "A6QPY8-1", "F1N4S5-1", "F1N6W2-1", "G3X8B1-1", "A0A3Q1LI03-1", "A0AAA9TG77-1", "F1MNW5-1", "E1B9G4-1", "G3MXV0-1", "Q2KJC8-1", "A0AAF6YJC8-1", "A0AAF6YJR2-1", "P26882-1", "F6RD06-1", "Q32PA9-1", "Q0P5D0-1", "Q2KJ44-1", "Q2HJ89-1", "Q08E11-1", "Q9TRY0-1", "A0A3Q1LK42-1", "A4FV72-1", "P26884-1", "P30404-1", "P62935-1", "P68107-1", "Q29RZ2-1", "P80311-1", "A0AAA9RV00-1", "F1MU79-1", "A0A3Q1LJJ1-1", "Q5E992-1", "Q2YDL5-1", "A0AAA9U018-1", "A0ABI0NKM5-1", "A0ABI0NMT7-1", "A0A3Q1LSB7-1" ], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-BTA-9770141", "name": "Formation of the Spliceosomal C* complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-5688092", "R-BTA-5688093", "R-BTA-72073", "R-BTA-9769591", "R-BTA-9769593", "R-BTA-9769594", "R-BTA-9769596", "R-BTA-9769598", "R-BTA-9769599", "R-BTA-9769601" ], "output_participant_list": [ "R-BTA-72060", "R-BTA-8867898", "R-BTA-9770419", "R-BTA-9770425", "R-BTA-9770427", "R-BTA-9770428", "R-BTA-9770430" ], "enzyme_list": [ "P19120-1", "A5PJW8-1", "G3MZY8-1", "Q17R09-1", "Q29RZ2-1", "A0AAA9RV00-1", "Q08E38-1", "Q2NL22-1", "E1BH78-1", "F1MEM4-1", "F1N6W2-1", "A0A3Q1MR43-1", "A0A3Q1M155-1", "Q3T147-1", "Q5E992-1", "E1B9G4-1", "E1BDN4-1" ], "evidence": [ { "id": "R-BTA-9770141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770141" } ] }, { "id": "R-BTA-9770236", "name": "Formation of the Spliceosomal P complex and exon ligation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-9769588", "R-BTA-9769590", "R-BTA-9769602" ], "output_participant_list": [ "R-BTA-6791189", "R-BTA-8849139", "R-BTA-8952113" ], "enzyme_list": [ "P19120-1", "A5PJW8-1", "G3MZY8-1", "Q29RZ2-1", "A0AAA9RV00-1", "Q08E38-1", "Q2NL22-1", "E1BH78-1", "F1MEM4-1", "F1N6W2-1", "A0A3Q1MR43-1", "A0A3Q1M155-1", "Q3T147-1", "Q5E992-1", "E1B9G4-1" ], "evidence": [ { "id": "R-BTA-9770236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770236" } ] }, { "id": "R-BTA-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19120-1", "A5PJW8-1", "G3MZY8-1", "Q17R09-1", "Q29RZ2-1", "A0AAA9RV00-1", "Q08E38-1", "Q2NL22-1", "E1BH78-1", "F1N6W2-1", "A0A3Q1MR43-1", "A0A3Q1M155-1", "Q3T147-1", "Q5E992-1", "E1B9G4-1", "E1BDN4-1" ], "evidence": [ { "id": "R-BTA-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9794542" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-5688092", "participant_name": "DHX8 [nucleoplasm]", "crossref": [ { "id": "F1MEM4", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000008339", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000010976", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000010976", "database": "ENSEMBL", "url": "" }, { "id": "NP_001193020.2", "database": "RefSeq", "url": "" }, { "id": "28059", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-5688093", "participant_name": "PRPF18 [nucleoplasm]", "crossref": [ { "id": "Q2HJ41", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000017244", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000022912", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000022912", "database": "ENSEMBL", "url": "" }, { "id": "NP_001068791.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-6791189", "participant_name": "MTREX [nucleoplasm]", "crossref": [ { "id": "34649", "database": "VGNC", "url": "" }, { "id": "A6H714", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-BTA-72060", "participant_name": "DHX38 [nucleoplasm]", "crossref": [ { "id": "57044", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000042866", "database": "ENSEMBL", "url": "" }, { "id": "3.6.4.13", "database": "IntEnz", "url": "" }, { "id": "Q17R09", "database": "UniProt", "url": "" }, { "id": "ENSBTAT00000045480", "database": "ENSEMBL", "url": "" }, { "id": "NP_001069266.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000013265", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-72073", "participant_name": "SLU7 [nucleoplasm]", "crossref": [ { "id": "Q3ZBE5", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000008457", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000011131", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000011131", "database": "ENSEMBL", "url": "" }, { "id": "NP_001160089.1", "database": "RefSeq", "url": "" }, { "id": "34971", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-8849139", "participant_name": "DDX39B [nucleoplasm]", "crossref": [ { "id": "NP_001028801.1", "database": "RefSeq", "url": "" }, { "id": "Q3T147", "database": "UniProt", "url": "" }, { "id": "ENSBTAP00000029090", "database": "ENSEMBL", "url": "" }, { "id": "27965", "database": "VGNC", "url": "" }, { "id": "ENSBTAG00000014490", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000029090", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-8867898", "participant_name": "CWC25 [nucleoplasm]", "crossref": [ { "id": "ENSBTAG00000030591", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000034838", "database": "ENSEMBL", "url": "" }, { "id": "27842", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000034722", "database": "ENSEMBL", "url": "" }, { "id": "F1MER3", "database": "UniProt", "url": "" }, { "id": "NP_001421814.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-8952113", "participant_name": "PPIL4 [nucleoplasm]", "crossref": [ { "id": "33204", "database": "VGNC", "url": "" }, { "id": "ENSBTAG00000016980", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000022582", "database": "ENSEMBL", "url": "" }, { "id": "F1N6W2", "database": "UniProt", "url": "" }, { "id": "ENSBTAP00000022582", "database": "ENSEMBL", "url": "" }, { "id": "XP_059745765.1", "database": "RefSeq", "url": "" } ] }, { 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"MDTEEDMSEFLMPIDKEKDSSESALCGRKLPLWLGLLLLLVAVGLLVPMIYFAVIANSKACVDGLQAQKECQEVNQHVQRQLNQAQELLHKKEAEAATCKQAVVTLRDSLKKEQARVEELQGELASLNQQLQDALTKERRKSEASAEDNGSVWFFMLLMCTFIICKCLKK", "length": 170, "header": "tr|F1N713-1|F1N713_BOVIN Isoform 1 of Bone marrow stromal antigen 2 OS=Bos taurus OX=9913 GN=LOC112441507 PE=4 SV=3 CANONICAL=F1N713-1" }, "locus": { "chromosome": "7", "start_pos": 5737508, "end_pos": 5735682, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010544.8", "url": "https://www.ensembl.org/id/ENSBTAT00000010544.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010544.6", "url": "https://www.ensembl.org/id/ENSBTAP00000010544.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:112441507", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112441507", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1N713", "url": "https://www.uniprot.org/uniprotkb/F1N713" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1N713", "url": "https://www.uniprot.org/uniprotkb/F1N713" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1N713", "url": "https://www.uniprot.org/uniprotkb/F1N713" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "F1N713", "url": "https://www.uniprot.org/uniprotkb/F1N713" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase inhibitor activity", "id": "GO:0008191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008191", "evidence": [ { "database": "UniProtKB", "id": "F1N713", "url": "https://www.uniprot.org/uniprotkb/F1N713" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N713-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 170, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N713-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N713" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N752-1", "uniprot_ac": "F1N752", "uniprot_id": "F1N752_BOVIN", "mass": { "chemical_mass": 130880.0, "monoisotopic_mass": 130880.0 }, "refseq": { "ac": "NP_001179440", "name": "ferroxidase HEPHL1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179440" }, "gene_names": [ { "name": "HEPHL1", "type": "recommended", "evidence": [ { "id": "F1N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N752" } ] }, { "name": "HEPHL1", "type": "synonym", "evidence": [ { "id": "NP_001179440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179440" } ] } ], "protein_names": [ { "name": "ferroxidase", "type": "recommended", "evidence": [ { "id": "F1N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N752/entry#names_and_taxonomy" } ] }, { "name": "1.16.3.1", "type": "synonym", "evidence": [ { "id": "F1N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N752/entry#names_and_taxonomy" } ] }, { "name": "ferroxidase HEPHL1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001179440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179440" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N752", "url": "https://www.uniprot.org/uniprotkb/F1N752" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HEPHL1", "url": "https://www.uniprot.org/uniprotkb/F1N752", "locus": { "chromosome": "29", "start_pos": 679014, "end_pos": 770780, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000022960", "url": "https://www.ensembl.org/id/ENSBTAG00000022960" } ] } } ], "crossref": [ { "id": "F1N752", "url": "https://alphafold.ebi.ac.uk/entry/F1N752", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000022960", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000022960", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11021", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11021", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519580", "url": "https://www.ncbi.nlm.nih.gov/gene/519580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519580", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PEPDMCV", "url": "https://omabrowser.org/oma/group/PEPDMCV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N752", "url": "https://www.orthodb.org/?gene=F1N752", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11709", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11709", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11709:SF233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11709:SF233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07731", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07731", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N752", "url": "https://www.uniprot.org/uniprotkb/F1N752", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N752-1", "url": "https://www.uniprot.org/uniprotkb/F1N752-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPWKWQADSILLLTLLGLSGLVGAVTRTYHIGIVEEYWNYVPQGKNVITGKSFAEDKLATLYLERGPNRIGSLYKKAVYRHYTDETYSKEIPKPPWLGFLGPILKAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGALYPDGTSGRNKDDDMVPPGKNYTYVWPVREEYAPAPADANCLTWVYHSHIDAPKDICSGLIGPLLVCKEGILHSYSGTRTDVDREFVIMFTLVDENQSWYLDENIRQFCTDPDSVDKKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHRTDVVNLFPATFLTIEMIVENPGKWMITCQVSDHLQAGMLGQYNVGNCKSGISHPKMKGQQRRYFIAAEKILWDYGPQGYDKFSGLPLNASGSDSELYFTQGNNRIGGKYWKARYTEYVDATFTRRKRFSEAEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPNVDGFLKPGAHVKPGEIFTYRWTVPESVSPTADDPPCLTYLYFSAVEPIKDTSSGLVGPLLVCKRGVLNADATQKGIDKEFYLLVTVFDENLSRYLDENIQKFTWHPFSVDKEDKEFVKSNRMHAINGYMYGNQPGLTMCKKDRVSWHLIGMGTDTDMHGVYFQGNTIHLRGTHRDSLALFPHVSTTAFMQPDRAGIFRVFCSTLHHLARGMHQIYEVSSCGNKYPPDQPYGMIRTFYIAAEEVEWDYAPNKNWEFEKQHLDARGERHGDIFMNHTENWIGSQYKKVVYREYTNGEFVEIKARPPREEHLALLGPMIHAEVGDSILIIFMNKASRPYSISAQGVEDVDSGKRLQVPVTKPGEIKTYRWNVPKRSGPGPSDPNCIPWLYYSTVNFVKDTYSGLVGPLITCREGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKPSDDFEESNKMHAINGKIYGNLHGLVMNEDTMTNWYLLGVGDEVDIHTIHYHAESFLFKIGKSYREDVHDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTKSPSGGASGSAPSNEPGEEQLYFFGQSLDPRGARAALVILFVLGLLLLVLSVVLSLKLCSARPRAAYQEVQSCALPTDAL", "length": 1157, "header": "tr|F1N752-1|F1N752_BOVIN Isoform 1 of ferroxidase OS=Bos taurus OX=9913 GN=HEPHL1 PE=3 SV=3 CANONICAL=F1N752-1" }, "isoforms": [ { "isoform_ac": "F1N752-1", "url": "https://www.uniprot.org/uniprotkb/F1N752/entry", "sequence": { "sequence": "MPWKWQADSILLLTLLGLSGLVGAVTRTYHIGIVEEYWNYVPQGKNVITGKSFAEDKLATLYLERGPNRIGSLYKKAVYRHYTDETYSKEIPKPPWLGFLGPILKAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGALYPDGTSGRNKDDDMVPPGKNYTYVWPVREEYAPAPADANCLTWVYHSHIDAPKDICSGLIGPLLVCKEGILHSYSGTRTDVDREFVIMFTLVDENQSWYLDENIRQFCTDPDSVDKKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHRTDVVNLFPATFLTIEMIVENPGKWMITCQVSDHLQAGMLGQYNVGNCKSGISHPKMKGQQRRYFIAAEKILWDYGPQGYDKFSGLPLNASGSDSELYFTQGNNRIGGKYWKARYTEYVDATFTRRKRFSEAEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPNVDGFLKPGAHVKPGEIFTYRWTVPESVSPTADDPPCLTYLYFSAVEPIKDTSSGLVGPLLVCKRGVLNADATQKGIDKEFYLLVTVFDENLSRYLDENIQKFTWHPFSVDKEDKEFVKSNRMHAINGYMYGNQPGLTMCKKDRVSWHLIGMGTDTDMHGVYFQGNTIHLRGTHRDSLALFPHVSTTAFMQPDRAGIFRVFCSTLHHLARGMHQIYEVSSCGNKYPPDQPYGMIRTFYIAAEEVEWDYAPNKNWEFEKQHLDARGERHGDIFMNHTENWIGSQYKKVVYREYTNGEFVEIKARPPREEHLALLGPMIHAEVGDSILIIFMNKASRPYSISAQGVEDVDSGKRLQVPVTKPGEIKTYRWNVPKRSGPGPSDPNCIPWLYYSTVNFVKDTYSGLVGPLITCREGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKPSDDFEESNKMHAINGKIYGNLHGLVMNEDTMTNWYLLGVGDEVDIHTIHYHAESFLFKIGKSYREDVHDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTKSPSGGASGSAPSNEPGEEQLYFFGQSLDPRGARAALVILFVLGLLLLVLSVVLSLKLCSARPRAAYQEVQSCALPTDAL", "length": 1157, "header": "tr|F1N752-1|F1N752_BOVIN Isoform 1 of ferroxidase OS=Bos taurus OX=9913 GN=HEPHL1 PE=3 SV=3 CANONICAL=F1N752-1" }, "locus": { "chromosome": "29", "start_pos": 770614, "end_pos": 679579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010500.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010500.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010500.6", "url": "https://www.ensembl.org/id/ENSBTAP00000010500.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:519580", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519580", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K8Q3-1", "protein_name": "ferroxidase", "gene_name": "Hephl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLKQPGGCILLEFLGLLGLVGAVTRTYYIGIVEEYWNYVPQGKDVITGKSFSEDKLATLFLERGPNRIGGIYKKAVYRHFTDGSYSTEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGALYPDGTSGKNKEDDMVPPGKNYTYVWPVREEYAPAPADANCLTWVYHSHIDAPKDICSGLIGPLLVCKEGVLNRHSGARTDVDREFVIMFTLVDENQSWYLDDNIRQFCTNPSSVDKSDAVFQRSNKMHALNGFLFGNLPEPEMCVGESVSWHLFGMGNEIDIHSIYFYGNTFITRGHRADVVNLFPATFLTTEMIVENPGKWMITCQVSDHLQAGMLGQYNVGNCRGNAPHPKMRGQQRRYFIAAEKVLWDYSPQGYDKFTGFPLNTSGSDSAVYFTQADNRIGGKYWKARYTEYVDATFSRRKMPSDSEAHLGILGPVIKAEVGDILLVTFANKADKVYSILPHGVFYDKASDAGPNVDGFLKPGAHVKPGETFTYRWTVPESVSPTDDDPPCLTYLYFSAVQPIKDTSAGLVGPLLVCKKGTLNADGTQKGIDKEFYLLFTVFDENFSSYLDENIQKFTWHPFSVDKEDKEFVKSNRMHAINGYMYGNQPGLSMCKKDRVSWHLIGMGTDTDMHGVYFQGNTIHLRGTHRDSLALFPHMSTTAFMQPDHSGIFKVFCSTLHHFTRGMGQIYEVSSCGNRDPSEPPYGMLRTFYIAAEEVEWDYAPNKNWEFEKQHLDAGGERHGDIFMNHTENWIGSQYRKVVYREYTNGEFVEIKARPPQEEHLQLLGPMIHAEVGDSILIIFKNKASRPYSITAQGVEDSDSGKFLDVPVTKPGEIKTYRWNVPKRSGPGPSDPNCIPWVYFSTANFVKDTYSGLMGPLITCREGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFRHTDDFEESNRMHAINGKIFGNLPGLIMTEDSMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTKSPSGAGPHAVTVPSQEQPGQEDLYFFGKSLRPRGAKAALVILFILGLLLLVATVILALRLRSSRRQMAYREVQSCALPTDAL", "length": 1159 }, "evidence": [ { "id": "F1N752", "url": "https://omabrowser.org/oma/group/F1N752/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XUG3-1", "protein_name": "ferroxidase", "gene_name": "HEPHL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPPLWGGGCLRTLGFFCLFSVVETRIRTYYLGIVEENWDYAPSGKNLITGQNLLEDKFASVYATRGANRIGRVYKKAIFRQYTDDTYSQEIPKAAWLGFLGPVLKAEEEDVFIIHLKNFASRPYSVHPHGVFYDKDSEGALYPDGTGGKSKEDDFVVPGGNYTYTWPVRKSYSPTLADSNCLTWIYHSHIDTPRDIASGLIGPLLVCKKGTADETSIERTGAANAFALMFSIVDENVSWYLDENINTFCLEPATVNKEDEGFQTSNRMHAINGYIYGNLPGLEMCADTPMSWHLFGMGSEIDIHAAYFYGHTFTNRDQRADVVGLFAATFITAEMTPGNPGRWLITCQVNEHLRGGMEALYDVQICQKNLSRPSPLSHKRRYYIAAEEVLWNYGPDGYDKFTGQGLNATGSESAIYFTQGIDRIGGLYWKVRYVEYTDATFSKRKIQPENMKHLGILGPVIKAEVGDTVLVTFANKARRSYSIMAHGVSFSKLSEGAPYLDGYMKPGAHVKPGETFTYKWRVPENGGPSESDPPCLTYLYYSATDAVKDTNSGLVGPLLVCRKNALNEDGTQKGIDREFYLLFSIFDENDSWYLNKNIEAFTGDPSKVDENDADFKESNKMHAVNGYLFGNLPGLAMCKDDKVSWHLIGLGSHYDMHGVQFQGNNIDLRGTTRDGLALFPHLSGTALMQPDRVGTFKVVCRTFDHFVGGMKHLYEVSSCRNASRAQQQHGAVRLYYIAAEEVEWDYASNKSSAPKIYNVSSNEESYGHIFLSQGEDLIGTKYKKVVYREYTNGNFTERKERTEEEEHLEILGPLLHAEVGDSVLIVFKNKASRPYSVSAHGVEEVGCEEQTEAPITLPGEINTYRWNVPERSGPGKTDPNCITWVYYSTANFVKDTYSGLIGPLVVCRKGILDKNGLRKDIDREFTLLFMVFDENKSWYLKENIETYLHKSPDDFNFTKNFVEGNSKHAINGKIYNSLLGLTMNEGDTTNWYLIGMGNEVDVHTVHFHAQTFIFKTDKGHRGDVFDLFPGTFQTVELVAENPGTWLLHCHVADHIHAGMETTYTINKSELEAPSGGGLTTAAYGTTTAQNRTTTKDPDSQGDNVFGKALNPREASLMLAAFVSVGLILLLTTLAFLSLITHQGSRIQYQALRDKSALLADSL", "length": 1162 }, "evidence": [ { "id": "F1N752", "url": "https://omabrowser.org/oma/group/F1N752/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LGG0-1", "protein_name": "ferroxidase", "gene_name": "HEPHL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPRKRQAACILLTFLGLSGLVGAVTRTYYLGIVEEYWNYVPQGKNIITGRSFSEDKLATLFLERGPNRIGSLYKKAVYRHYTDETYSTEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGALYPDGTSGRNKDDDRVPPGKNYTYVWPVREEYAPAPADANCLTWVYHSHIDAPKDICSGLIGPLLVCKEGILHKYSGTRTDVDREFVIMFTLVDENQSWYLDENIRHFCTDPDSVDKHDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHRTDVVNLFPATFLTTEMIVENPGKWMITCQVSDHLQAGMLGQYNVGNCKSGTSHPKMKGQQRHYFIAAEKILWDYGPQGYNKFSGLPLNASGSGSEFYFTQGDNRIGGRYWKARYTEYVDATFAQRKRLSEAEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPNLDGFLKPGAHVKPGETFTYRWTVPESVSPTADDPPCLTYLYFSAVEPIKDTSSGLVGPLLVCKKGTLNADGTQKGIDKEFYLLFTVFDENLSRYLDENVQKFTWRPFAVDKEDKEFVKSNRMHAINGYMYGNQPGLTMCKKDRVSWHLIGMGTDTDMHGVYFQGNTIHLRGTHRDSLALFPHVATTAFMQPDRAGIFRVFCSTLHHFERGMNQIYEVSSCGNKDPSEQPYGMIRTFYIAAEEVEWDYAPNKNWEFEKQHLDAGRERHGDIFMNHTENWIGSQYKKVVYREYTNGEFVEIKARLPREEHLALLGPMIHAEVGDSILIVFMNKANRPYSISAQGVEDMDTGRQLQVPITKPGEIKTYRWTVPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCREGVLNEKGRRSDVDYEFALLFLVFNENESWYLDENIKKYLNKDPRDFKPSDDFEESNKMHAINGKIFGNLHGLIMNEDSMTNWYLLGIGSEVDIHTVHYHAESFLFKIDKSYREDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLQNLDNRILYSTKSPGGAPQPATVPSNEEPGKEQLYFFGKNLGPRGAKAALVILFIIGLFLLMVTVILSLCLRWARKQVAYQEVQSCALPTDAL", "length": 1158 }, "evidence": [ { "id": "F1N752", "url": "https://omabrowser.org/oma/group/F1N752/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3V1H3-1", "protein_name": "Ferroxidase HEPHL1", "gene_name": "Hephl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLKQPGGCILLQFLGLLGLVGAVTRTYYIGIVEEYWNYVPQGKDVITGKSFSEDKLATLFLERGPNRIGGIYKKAVYRHFTDGSYSTEIPKPPWLGFLGPILRAEVGDVIVIHLMNFASRPFSLHPHGVFYDKDSEGALYPDGTSGRNKEDDMVPPGKNYTYVWPVREEYAPAPADANCLTWVYHSHIDAPKDICSGLIGPLLVCKEGVLNRYSGMRTDVDREFVIMFTLVDENQSWYLDDNIKQFCTNPNSVDKSDAVFQRSNKMHALNGFLFGNMPEPEMCVGESVSWHLFGMGNEIDIHSIYFYGNTFITRGHRADVVNLFPATFLTTEMIVENPGKWMITCQVSDHLQAGMLGQYSVGNCRGNAPHPKVQGQQRRYFIAAEKVLWDYGPQGYDKFTGFPLNTSGSDSAVYFTQADNRIGGKYWKARYTEYVDATFSRRKMPSDSEAHLGILGPVIKAEVGDILLVTFANKADKVYSILPHGVFYDKASDAAPNVDGFLKPGAHVKPGETFTYRWTVPESVSPTDEDPPCLTYLYFSAVQPIKDTSAGLVGPLLVCKKGTLNADGTQKGIDKEFYLLFTVFDENFSSYLDENIKKFTWHPFSVDKEDKEFVKSNRMHAVNGYMYGSQPGLSMCKKDRVSWHLIGMGTDTDMHGVYFQGNTIHLRGTHRDSLALFPHMATTAYMQPDHSGIFKVFCSTLPHFTRGMGQIYEISSCGNRDPSEPPYGMLRTFFIAAEEVEWDYAPNKNWEFEKQHLDAGGERHGDIFMNHTENWIGSQYRKVVYREYTNGEFVEIKARPPQEEHLQLLGPMIHAEVGDSILIIFKNKASRPYSIAAQGVEDSNNGKLLNVPVTKPGEIKTYRWNVPKRSGPGPSDPNCIPWVYFSTANFVKDTYSGLMGPLITCREGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKHTDDFEESNKMHAINGKIFGNLPGLIMTEDSMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTKTPSGAGSHAVTVPSQEQPGKEELYFFGKNLRPRGAKAALVILFILGLLLLVATVVLALRLRSSRRQMAYREVQSCALPTDAL", "length": 1159 }, "evidence": [ { "id": "F1N752", "url": "https://omabrowser.org/oma/group/F1N752/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6MZM0-1", "protein_name": "Ferroxidase HEPHL1", "gene_name": "HEPHL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRKQPAGCIFLLTFLGLSGLVGTVTRTYYIGIVEEYWNYVPQGKNVITGKSFTEDKLATLFLERGPNRIGSIYKKAVYRRFTDGTYSIEIPKPPWLGFLGPILRAEVGDVIVIHLKNFASRPYSLHPHGVFYNKDSEGALYPDGTSGRNKNDDMVPPGKNYTYVWPVREEYAPTPADANCLTWVYHSHIDAPKDICSGLIGPLLVCKEGILNRYSGTRNDVDREFVIMFTLVDENQSWYLNENIKHFCTNPDSVDKKDAVFQRSNKMHALNGYLFGNFPEPDMCVGESVSWHLFGMGNEIDIHSIYFYGNTFISRGHRTDVVNLFPATFLTTEMIAENPGKWMITCQVSDHLQAGMLGQYNVDNCKSDIFYPKMKGQQRRYFIAAEKILWDYAPQGYNKFSGLPLNASGSDSDLYFTQGDNRIGGKYWKVRYTEFVDATFTKRKRLSAEEAHLGILGPVIKAEVGDTLLVTFANKADKVYSILPHGVIYDKASDAAPNLDGFVKPGAHVKPGETFTYKWTVPESVSPTAGDPPCLTYLYFSAVDPIKDTSSGLVGPLLVCKKGVLNADGTQKGIDKEFYLLFTVFDENLSRYFDENIQKFIWHPFSIDKEDKEFVKSNRMHAVNGYMYGNQPGLNMCKRDRVSWHLIGLGTDTDMHGIVFQGNTIHLRGTHRDSLALFPHMATTAFMQPDHAGIFRVFCATMPHLSRGMGQIYEVSSCDNRDPSEQRYGMIRTFYIAAEEVEWDYAPNKNWEFEKQHVDARGERHGDIFMNRTENWIGSQYKKVVYREYTDGEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKASRPYSISAQGVEEMDSGKQFQVPMTKPGEVKTYRWNIPKRSGPGPSDPNCIPWVYYSTVNFVKDTYSGLMGPLITCRKGVLNEKGRRSDVDYEFALLFLVFNENESWYLDDNIKKYLNKDPRDFKRTDDFEESNRMHAINGKIFGNLHGLIMNEDTMTNWYLLGIGSEVDIHTIHYHAESFLFKIDKSYREDVYDLFPGTFQTIELFADHPGTWLLHCHVSDHIHAGMETTYTVLRNIDNRIPYSTTSPGVASHPATVPSNERPGKEQLYFFGKNLGPTGAKAALVILFIIGLLLLITTVILSLRLCSAMKQTDYQQVQSCALPTDAL", "length": 1159 }, "evidence": [ { "id": "F1N752", "url": "https://omabrowser.org/oma/group/F1N752/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N752", "url": "https://www.uniprot.org/uniprotkb/F1N752" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "F1N752", "url": "https://www.uniprot.org/uniprotkb/F1N752" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "F1N752", "url": "https://www.uniprot.org/uniprotkb/F1N752" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "F1N752", "url": "https://www.uniprot.org/uniprotkb/F1N752" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "F1N752", "url": "https://www.uniprot.org/uniprotkb/F1N752" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N752-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1157, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N752-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N752" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N752", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N752" }, { "id": "PF07732", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07732" }, { "id": "PF07731", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07731" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Plastocyanin-like", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 207, "start_aa": "Phe", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.16.3.1", "ec_name": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "1.16.3.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.16.3.1" }, { "id": "1.16.3.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.16.3.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 589, "end_pos": 591 }, { "start_pos": 772, "end_pos": 774 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N775-1", "uniprot_ac": "F1N775", "uniprot_id": "F1N775_BOVIN", "mass": { "chemical_mass": 222721.0, "monoisotopic_mass": 222721.0 }, "refseq": { "ac": "NP_001193103", "name": "myosin-8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193103" }, "gene_names": [ { "name": "MYH8", "type": "recommended", "evidence": [ { "id": "F1N775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ] }, { "name": "MHC 67", "type": "synonym", "evidence": [ { "id": "NP_001193103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193103" } ] }, { "name": "MYH8", "type": "synonym", "evidence": [ { "id": "NP_001193103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193103" } ] } ], "protein_names": [ { "name": "Myosin heavy chain 8", "type": "synonym", "evidence": [ { "id": "F1N775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N775/entry#names_and_taxonomy" } ] }, { "name": "myosin heavy-chain 67", "type": "synonym", "evidence": [ { "id": "NP_001193103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193103" } ] }, { "name": "myosin, heavy polypeptide 8, skeletal muscle, perinatal", "type": "synonym", "evidence": [ { "id": "NP_001193103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193103" } ] }, { "name": "myosin-8", "type": "synonym", "evidence": [ { "id": "NP_001193103", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193103" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYH8", "url": "https://www.uniprot.org/uniprotkb/F1N775", "locus": { "chromosome": "19", "start_pos": 29403330, "end_pos": 29433093, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009702", "url": "https://www.ensembl.org/id/ENSBTAG00000009702" } ] } } ], "crossref": [ { "id": "ENSBTAG00000009702", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01377", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01377", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281339", "url": "https://www.ncbi.nlm.nih.gov/gene/281339", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281339", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281339", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NITHVHT", "url": "https://omabrowser.org/oma/group/NITHVHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKJ5", "url": "https://www.orthodb.org/?gene=A0A3Q1LKJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVZ9", "url": "https://www.orthodb.org/?gene=A0A3Q1LVZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N775", "url": "https://www.orthodb.org/?gene=F1N775", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193103", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193103", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKJ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N775-1", "url": "https://www.uniprot.org/uniprotkb/F1N775-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSIIQSKEGGKVTVKTERGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTSEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGRAEAHFSLIHYAGTVDYNIAGWLDKNKDPLNDTVVGLYQKSSMKTLASLFSTYASAEADSGAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPDGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADALADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEMNAELTAKKRKLEDECAELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEVIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLNKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESMVDIENDKQQLDEKLKKKEFEISNLLSKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKLRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLSSNAETVAKAKGNLEKMCRTLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRTKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIEQLKRNHIRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAIKGLRKHERKVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKLRKLQHELEEAEERADIAESQVNKLRVKSREIHTKVSAE", "length": 1937, "header": "tr|F1N775-1|F1N775_BOVIN Isoform 1 of Myosin heavy chain 8 OS=Bos taurus OX=9913 GN=MYH8 PE=3 SV=3 CANONICAL=F1N775-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKJ5/entry", "sequence": { "sequence": "MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSIIQSKEGGKVTVKTERGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTSEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGRAEAHFSLIHYAGTVDYNIAGWLDKNKDPLNDTVVGLYQKTFSSSTSATVELPSSMHCDLFLGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPDGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADALADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEMNAELTAKKRKLEDECAELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEVIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLNKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESMVDIENDKQQLDEKLKKKEFEISNLLSKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKLRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLSSNAETVAKAKGNLEKMCRTLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRTKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIEQLKRNHIRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAIKGLRKHERKVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKLRKLQHELEEAEERADIAESQVNKLRVKSREIHTKVSAE", "length": 1889, "header": "tr|A0A3Q1LKJ5-1|A0A3Q1LKJ5_BOVIN Computationally mapped isoform of Myosin heavy chain 8 OS=Bos taurus OX=9913 GN=MYH8 PE=3 SV=1 CANONICAL=F1N775-1" }, "locus": { "chromosome": "19", "start_pos": 29431505, "end_pos": 29403466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087465.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087465.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060133.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060133.1" } ] } }, { "isoform_ac": "A0A3Q1LVZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ9/entry", "sequence": { "sequence": "MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSIIQSKEGGKVTVKTERGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTSEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGRAEAHFSLIHYAGTVDYNIAGWLDKNKDPLNDTVVGLYQKSSMKTLASLFSTYASAEAASGIHSLMGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPDGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADALADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEMNAELTAKKRKLEDECAELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEVIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLNKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESMVDIENDKQQLDEKLKKKEFEISNLLSKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKLRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLSSNAETVAKAKGNLEKMCRTLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRTKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIEQLKRNHIRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAIKGLRKHERKVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKLRKLQHELEEAEERADIAESQVNKLRVKSREIHTKVSAE", "length": 1939, "header": "tr|A0A3Q1LVZ9-1|A0A3Q1LVZ9_BOVIN Computationally mapped isoform of Myosin heavy chain 8 OS=Bos taurus OX=9913 GN=MYH8 PE=3 SV=1 CANONICAL=F1N775-1" }, "locus": { "chromosome": "19", "start_pos": 29431505, "end_pos": 29403466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085880.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085880.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061605.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061605.1" } ] } }, { "isoform_ac": "F1N775-1", "url": "https://www.uniprot.org/uniprotkb/F1N775/entry", "sequence": { "sequence": "MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSIIQSKEGGKVTVKTERGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTSEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGRAEAHFSLIHYAGTVDYNIAGWLDKNKDPLNDTVVGLYQKSSMKTLASLFSTYASAEADSGAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPDGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADALADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEMNAELTAKKRKLEDECAELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEVIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLNKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESMVDIENDKQQLDEKLKKKEFEISNLLSKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKLRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLSSNAETVAKAKGNLEKMCRTLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRTKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIEQLKRNHIRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAIKGLRKHERKVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKLRKLQHELEEAEERADIAESQVNKLRVKSREIHTKVSAE", "length": 1937, "header": "tr|F1N775-1|F1N775_BOVIN Isoform 1 of Myosin heavy chain 8 OS=Bos taurus OX=9913 GN=MYH8 PE=3 SV=3 CANONICAL=F1N775-1" }, "locus": { "chromosome": "19", "start_pos": 29431505, "end_pos": 29403466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061119.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061119.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053653.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053653.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:281339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281339", "resource": "KEGG Pathway" }, { "id": "R-BTA-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AMA4-1", "protein_name": "Myosin heavy chain 8", "gene_name": "MYH8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSASSDAEMAIFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVTEPKESYVKSIIQSKEGGKVTVKTERGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVLKGRAEAHFSLIHYAGTVDYNIAGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSGTKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPDGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKEELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADALADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLNKAKAKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIIDIENDKQQLDEKLKKKEFEISNLLSKIDDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLSSNAETISKAKGNLEKMCRTLEDQMSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRTKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACTALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQLEQEKCDIQAALEEAEASLEHEEGKILRIQLELNQVKADVDRKIAEKDEEIEQLKRNHIRVVESMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRASLLQAEVEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLESDISQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLAKIRKLQHELEEAEERADIAESQVNKLRVKSREIHPKVSAE", "length": 1939 }, "evidence": [ { "id": "F1N775", "url": "https://omabrowser.org/oma/group/F1N775/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P04462-1", "protein_name": "Myosin-8", "gene_name": "Myh8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RAALQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNASLINAKKKLENDVSQLQSEVEEVIQRARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE", "length": 257 }, "evidence": [ { "id": "F1N775", "url": "https://omabrowser.org/oma/group/F1N775/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13535-1", "protein_name": "Myosin-8", "gene_name": "MYH8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE", "length": 1937 }, "evidence": [ { "id": "F1N775", "url": "https://omabrowser.org/oma/group/F1N775/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13542-1", "protein_name": "Myosin-8", "gene_name": "Myh8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAGSDAEMAIFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSVIQSKDGGKVTVKTESGATLTVKEDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFSPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQCLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPTKGKAEAHFSLVHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADGGAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGYLMRVEYQKMLLRRESIFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEMNKKRETEFQKLRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKVLSEWRQKYEETQAELESCQKESRTLSTELFKVKNAYEESLDHLETLRRENKNLQQEISDLTEQIAEGGKHIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHVRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE", "length": 1937 }, "evidence": [ { "id": "F1N775", "url": "https://omabrowser.org/oma/group/F1N775/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "muscle filament sliding", "id": "GO:0030049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030049", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" }, { "name": "ATP metabolic process", "id": "GO:0046034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046034", "evidence": [ { "database": "UniProtKB", "id": "F1N775", "url": "https://www.uniprot.org/uniprotkb/F1N775" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1723, "end_pos": 1725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 980, "end_pos": 982, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N775" }, { "id": "PS51844", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51844" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin N-terminal SH3-like", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 84, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N775" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 781, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1723, "end_pos": 1725 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 729, "end_pos": 731 }, { "start_pos": 980, "end_pos": 982 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"chondroitin sulfate synthase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179581" }, "gene_names": [ { "name": "CHSY3", "type": "recommended", "evidence": [ { "id": "F1N783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ] }, { "name": "CHSY3", "type": "synonym", "evidence": [ { "id": "NP_001179581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179581" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "F1N783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N783/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F1N783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N783/entry#names_and_taxonomy" } ] }, { "name": "chondroitin sulfate synthase 3", "type": "synonym", "evidence": [ { "id": "NP_001179581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179581" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N783", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHSY3", "url": "https://www.uniprot.org/uniprotkb/F1N783", "locus": { "chromosome": "7", "start_pos": 23975545, "end_pos": 24264195, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014661", "url": "https://www.ensembl.org/id/ENSBTAG00000014661" } ] } } ], "crossref": [ { "id": "F1N783", "url": "https://alphafold.ebi.ac.uk/entry/F1N783", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014661", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014661", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "528149", "url": "https://www.ncbi.nlm.nih.gov/gene/528149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528149", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528149", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CADRVNC", "url": "https://omabrowser.org/oma/group/CADRVNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N783", "url": "https://www.orthodb.org/?gene=F1N783", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179581", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N783", "url": "https://www.uniprot.org/uniprotkb/F1N783", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N783-1", "url": "https://www.uniprot.org/uniprotkb/F1N783-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPGAQQPLPEPHARQWPGQSPPPARQELRGPQLPEAAPGVTSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPVAEGEPEEEDGGAAGHRRSGQPGSSHNGSGDGGAAASSSRPRDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGVGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDIYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSHEVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGVMPSFNHFQPRERDEVIEWEFLTGKLLYSASENQPPRQSINSILRTALDDTVLQVMEMINENAKTRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSDTQSFSFISNSLKILSSFQGAKEVGGHSEKKIHILVPLIGRYDTFLRFMENFENTCLIPKQNVKLVIILFSKDSGQDSNKHIELIQEYQNKYPKAEITLIPMKGEFSRGLGLEMGSSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGSPPTDDDFVFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTVQLAELWLEKHLGVRYNRTLS", "length": 882, "header": "tr|F1N783-1|F1N783_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CHSY3 PE=3 SV=3 CANONICAL=F1N783-1" }, "isoforms": [ { "isoform_ac": "F1N783-1", "url": "https://www.uniprot.org/uniprotkb/F1N783/entry", "sequence": { "sequence": "MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPGAQQPLPEPHARQWPGQSPPPARQELRGPQLPEAAPGVTSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPVAEGEPEEEDGGAAGHRRSGQPGSSHNGSGDGGAAASSSRPRDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGVGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDIYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSHEVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGVMPSFNHFQPRERDEVIEWEFLTGKLLYSASENQPPRQSINSILRTALDDTVLQVMEMINENAKTRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSDTQSFSFISNSLKILSSFQGAKEVGGHSEKKIHILVPLIGRYDTFLRFMENFENTCLIPKQNVKLVIILFSKDSGQDSNKHIELIQEYQNKYPKAEITLIPMKGEFSRGLGLEMGSSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGSPPTDDDFVFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTVQLAELWLEKHLGVRYNRTLS", "length": 882, "header": "tr|F1N783-1|F1N783_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CHSY3 PE=3 SV=3 CANONICAL=F1N783-1" }, "locus": { "chromosome": "7", "start_pos": 24263996, "end_pos": 23976249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019521.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019521.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041677.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041677.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:528149", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528149", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YBC7-1", "protein_name": "Hexosyltransferase", "gene_name": "CHSY3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARSRRPWLSVVLGLVLGFTAASWLIAPRVAEMNEKKRRGASLCSYYSRAAGPGAAGGAAAAGEQPAAAAVLGGTGVRSSPWELPAAEDGTVSSPAAGGEAEQEEEEEGGEKRSGRPGGSRNGSGDWGGAAGCAKPRNFLYVGVMTAQKYLGSRAVAAQRTWAPSVPGRVEFFSSQGSAAPPGLPPLPVVALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGEKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRMGYIQDLHNSKIHTAITLHPNKRPAYQYRLHNYILSRKISELRYRTILLHRECALMSKLSNSKVTKEDQQLGVIPSFNHFQPRERSEVIEWEFLTGKFLYSMVESQPPRQSVSSVLRAALDDTVMQVMEMINENSRSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKVTVPVRRHAFLQQLFSKPFFREAEELDVRSLLEDTNTDTQSFSFPSNSFKIFSSSFQGTKDIVGHSDKKIHILVPLIGRFDIFSRFMENFEKTCLIPRQNVKLAIILFSSELGQDSIKHIDLMKEYSIKYPKADMTLVPMTGKFSRGLGLEMASSQFDNGTLLLFCDVDLIFTPDFLQRCRENTIQGEQVYYPIIFSQYDPKVVYGGNPPADSSFIFTKRTGFWREYGFGITCIYKSDLLTAGGFDTSIQGWGLEDVDLYTKVITSGLKAFRSQEVGVVHIFHPVRCDPSLDPKQYKMCLGSKASTFASTMQLAELWLEKRLGVRYNQTVS", "length": 850 }, "evidence": [ { "id": "F1N783", "url": "https://omabrowser.org/oma/group/F1N783/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M0R6S5-1", "protein_name": "Hexosyltransferase", "gene_name": "Chsy3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVRSRRPWVSVALGLVLGFTAASWLIAPRVAELSEKRRRGSSLCSYYGRSATGPRADAQQLLPQPQSQPRLQQSPPPASHQLPGPLRPEVAPGGPSLRSSPWQQPAPLPQRRRGHKPEGATALPGAPAAKGEPEEEDGGAAGPRKGGRPRSSQNGSGDGGAAAPTSGPGDFLYVGVMTAQKYLGSRALAAHRTWARFIPGRVEFFSSQQPPSAALGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNTEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGMMPSFNHFQPQERNEVMEWEFLTGKLLYSAAENQPPRQSINSILRSALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQPFSKPFFREMEELDINSLVESINSGTPATGFSFISNSLKILSSLQEPKEIGGHNEKKVHILVPLVGRYDIFLRFMENFESTCIIPKQNVKLVIILFSRDSGQESIKHIELIQEYQNRYPSAEMTLIPMKGEFSRGLGLEMGSSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTVQGQQVYYPIIFSQYDPKVTRMGNSPTEGDFVFSKETGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVIQSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMKLAELWLEKHLGVRDNRTLS", "length": 886 }, "evidence": [ { "id": "F1N783", "url": "https://omabrowser.org/oma/group/F1N783/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5DTK1-1", "protein_name": "Chondroitin sulfate synthase 3", "gene_name": "Chsy3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVRSRRPWVSVALGLVLGFTAASWLIAPRVAELSEKRRRGSSLCSYYGRSATGPRADAQQLLPQPQSRPRLEQSPPPASHELPGPQQPEAAPGGPSFRSSPWQQPALLPQRRRGHTPEGATALPGAPAAKGEPEEEDGGAADPRKGGRPGSSHNGSGDGGAAVPTSGPGDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQSPSAALGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNTEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNSEVSKEDQQLGRTPSFNHFQPRERNEVMEWEFLTGKLLYSAAENQPPRQSINSILRSALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVDPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQPFSKPFFREVEELDVNRLVESINSGTQSFSVISNSLKILSSLQEAKDIGGHNEKKVHILVPLVGRYDIFLRFMENFESTCLIPKQNVKLVIILFSRDAGQESIKHIELIQEYQSRYPSAEMMLIPMKGEFSRGLGLEMASSQFDNDTLLLFCDVDLIFRGDFLQRCRDNTVQGQQVYYPIIFSQYDPKVTHMRNPPTEGDFVFSKETGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRDNRTLS", "length": 884 }, "evidence": [ { "id": "F1N783", "url": "https://omabrowser.org/oma/group/F1N783/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q70JA7-1", "protein_name": "Chondroitin sulfate synthase 3", "gene_name": "CHSY3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNTEVSKEDQQLGVIPSFNHFQPRERNEVIEWEFLTGKLLYSAAENQPPRQSLSSILRTALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVNPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSETQSFSFISNSLKILSSFQGAKEMGGHNEKKVHILVPLIGRYDIFLRFMENFENMCLIPKQNVKLVIILFSRDSGQDSSKHIELIKGYQNKYPKAEMTLIPMKGEFSRGLGLEMASAQFDNDTLLLFCDVDLIFREDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGNPPTDDYFIFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRYNRTLS", "length": 882 }, "evidence": [ { "id": "F1N783", "url": "https://omabrowser.org/oma/group/F1N783/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7KUZ9-1", "protein_name": "Hexosyltransferase", "gene_name": "Chsy", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLQHTMTKRKTLIIGFFGIALGLCIGTMLKNYLALEIVKRCSLRPTNLKTPADIIGLRDEDTIQNSQRNLVFVGVMTAKSFLEGRARAVYDTWGKEVPGRMAFFSSEGSYSDDLPVVGLKNVDDRYPPQKKSFMMLYYMYEHYIDRFEWFIRADDDVYMEPDKLERFLRSIDSSKPQFIGQAGKGNSEEFGLLSLEFDENFCMGGPGVILSSETLRRVAPHIPSCLKNLYSTHEDVEVGRCVQKFAGIPCTWNYEMQYILRHNSSGRNAYTGKLKRKEIHNAITLHPIKQAPLMYRLHSYVQGLKAEEMRQESLLLHRDIKRMAKYLEVPDESTYMLPSVSPESDSTKRHFQDHNILGISPELNKFVPASTDDLLDWSFIARSLYSASSANPKQKIDSAMREGLEDAITEVMENINNYSRQRGRVIEFRELLYGYHRLDALHGQDMILDLLLIYKKYRGKKMTVPVRRHLYVQRAFTGIFVKEVDEDFYNVTLQQSLLGSLFQNGMARLSSHFTMPSGLLSPTQDKIVFVLPIAGRLGTFERFLRTYERVCVRGEQHCDLLVVIFGSPDELGDHLQLLHDLHARHVYQQVNWIQRSSAFSRGVALDVAARSSYIRQEDIILFIDVDMVFEVETLQRVRMHTQRGKQVYLPIVFSQYDPQRRSGDAGGSEDEGETPRIDDERGYFRQFGFGICAIYKSDILDEDINGFDKDITGWGLEDVKFLEKIVRVGTRQRGFLANTAELAMDYNEAAEQWRRLSVFRAPDPTLVHIYHDISCDVQLDAPQYNMCLGTKANSLGSTRLMEQLFHSSPENVQFAADFNRQKQQQQQQQQAR", "length": 832 }, "evidence": [ { "id": "F1N783", "url": "https://omabrowser.org/oma/group/F1N783/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1N783", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ], "pmid": "" }, { "name": "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity", "id": "GO:0050510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050510", "evidence": [ { "database": "UniProtKB", "id": "F1N783", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "F1N783", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "F1N783", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "F1N783", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 710, "end_pos": 712, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-1971487", "name": "Chondroitin polymerase complex transfers GalNAc to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N783-1", "F6PU96-1", "E1B9D0-1", "E1BMM8-1" ], "evidence": [ { "id": "R-BTA-1971487", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971487" } ] }, { "id": "R-BTA-1971491", "name": "Chondroitin polymerase complex transfers GlcA to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N783-1", "F6PU96-1", "E1B9D0-1", "E1BMM8-1" ], "evidence": [ { "id": "R-BTA-1971491", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971491" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1B9D0", "gene_name": "CHPF2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1B9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D0" } ] } ] }, { "uniprot_ac": "E1BMM8", "gene_name": "CHPF", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BMM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ] } ] }, { "uniprot_ac": "F1N783", "gene_name": "CHSY3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { 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"uniprot_id": "F1N7A0_BOVIN", "mass": { "chemical_mass": 88070.0, "monoisotopic_mass": 88070.0 }, "refseq": { "ac": "NP_001193701", "name": "probable E3 ubiquitin-protein ligase HECTD2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193701" }, "gene_names": [ { "name": "HECTD2", "type": "recommended", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "name": "HECTD2", "type": "synonym", "evidence": [ { "id": "NP_001193701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193701" } ] }, { "name": "hmm77879", "type": "synonym", "evidence": [ { "id": "NP_001193701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193701" } ] } ], "protein_names": [ { "name": "Probable E3 ubiquitin-protein ligase HECTD2", "type": "recommended", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0/entry#names_and_taxonomy" } ] }, { "name": "HECT domain containing 2", "type": "synonym", "evidence": [ { "id": "NP_001193701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193701" } ] }, { "name": "HECT domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0/entry#names_and_taxonomy" } ] }, { "name": "HECT-type E3 ubiquitin transferase HECTD2", "type": "synonym", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0/entry#names_and_taxonomy" } ] }, { "name": "probable E3 ubiquitin-protein ligase HECTD2", "type": "synonym", "evidence": [ { "id": "NP_001193701", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193701" } ] } ], "function": [ { "annotation": "E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.", "evidence": [ { "database": "UniProtKB", "id": "F1N7A0", "url": "https://www.uniprot.org/uniprotkb/F1N7A0#function" }, { "database": "UniProtKB", "id": "ARBA00056288", "url": "https://www.uniprot.org/uniprotkb/ARBA00056288#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7A0", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HECTD2", "url": "https://www.uniprot.org/uniprotkb/F1N7A0", "locus": { "chromosome": "26", "start_pos": 13101803, "end_pos": 13027923, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011651", "url": "https://www.ensembl.org/id/ENSBTAG00000011651" } ] } } ], "crossref": [ { "id": "F1N7A0", "url": "https://alphafold.ebi.ac.uk/entry/F1N7A0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011651", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011651", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "520752", "url": "https://www.ncbi.nlm.nih.gov/gene/520752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520752", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLMSEYY", "url": "https://omabrowser.org/oma/group/DLMSEYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7A0", "url": "https://www.orthodb.org/?gene=F1N7A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193701", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193701", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7A0", "url": "https://www.uniprot.org/uniprotkb/F1N7A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7A0-1", "url": "https://www.uniprot.org/uniprotkb/F1N7A0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEADRVPSPAAPPAVAASAPEEKKGKEPEREKLPPIVSAGASAPAGLDRGFKGQISTFSSVISTVNQKKEAAENRSSPTHLVFPNIKNVRDLPPISLDVRQKQRISTDPLSSEMKAPVLPEPILPVQPKTMKDFLEDVEKAKSSGDWKTVYDFYLTTFDSFPELSAAFKKDASASNTIEDSGINAKFVNAVYDALLNTPQDIQKTVLKGIINSLLQEWKGPRTKDDLRAYFILLQNPQFNNTSTYVIYAHLLRQTASLVEADHHFLAHWFKKLSQKRFKPLVERLLQFISLRLFPAKPEEFPPISKCSWWIPSASKVLALLNTANNLVHPPLIPYTDFYNSTLDHIDLMEEYHTWQSFGNSHRFSFCQYPFVISIAAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSYCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPIVPSDQNTPVGICSVTTDDLCQIMPELAHGLSELLSYEGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKIPVTNQNRKEYVQLYIDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDGYAKTDLTIRYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "length": 775, "header": "tr|F1N7A0-1|F1N7A0_BOVIN Isoform 1 of Probable E3 ubiquitin-protein ligase HECTD2 OS=Bos taurus OX=9913 GN=HECTD2 PE=4 SV=2 CANONICAL=F1N7A0-1" }, "isoforms": [ { "isoform_ac": "F1N7A0-1", "url": "https://www.uniprot.org/uniprotkb/F1N7A0/entry", "sequence": { "sequence": "MSEADRVPSPAAPPAVAASAPEEKKGKEPEREKLPPIVSAGASAPAGLDRGFKGQISTFSSVISTVNQKKEAAENRSSPTHLVFPNIKNVRDLPPISLDVRQKQRISTDPLSSEMKAPVLPEPILPVQPKTMKDFLEDVEKAKSSGDWKTVYDFYLTTFDSFPELSAAFKKDASASNTIEDSGINAKFVNAVYDALLNTPQDIQKTVLKGIINSLLQEWKGPRTKDDLRAYFILLQNPQFNNTSTYVIYAHLLRQTASLVEADHHFLAHWFKKLSQKRFKPLVERLLQFISLRLFPAKPEEFPPISKCSWWIPSASKVLALLNTANNLVHPPLIPYTDFYNSTLDHIDLMEEYHTWQSFGNSHRFSFCQYPFVISIAAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSYCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPIVPSDQNTPVGICSVTTDDLCQIMPELAHGLSELLSYEGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKIPVTNQNRKEYVQLYIDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDGYAKTDLTIRYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "length": 775, "header": "tr|F1N7A0-1|F1N7A0_BOVIN Isoform 1 of Probable E3 ubiquitin-protein ligase HECTD2 OS=Bos taurus OX=9913 GN=HECTD2 PE=4 SV=2 CANONICAL=F1N7A0-1" }, "locus": { "chromosome": "26", "start_pos": 13099431, "end_pos": 13028066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015476.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015476.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015476.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015476.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:520752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520752", "resource": "KEGG Pathway" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYF3-1", "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2", "gene_name": "Hectd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGCPHLPPRALSSAVLARDAGPRPEPRTTCGSRARPRARAGRAQGRRSLAAGPGRARWAAGTRADIRARGRAGGGGAAAAVGRSPLAAAAAAAPAPAAVRPPPPPPPPPPRASAARPDMSEAARDLSPGAPPAVAAAASEERKGKEPEREKLPPIVTAGAAAGLDRGSKGQISTFSSFVSSVTQKKEAAENRSSPTHLALPNIRNVRDLPPICLDVRQKQRMSMDSLSSEVKVPPLPEPILPSQPKTVKDFEEDLEKAEATGNWKTVHAFYITAFDSFTELNAAFKKDATASFNTIEDSGINANLVNAVFDALLNTPQDIQKSVLKGIINSLLQEWKGPRTKDDLRAYFILLQNPQFNITSTYVIYAHLLRQIATLVEADHHFLVHWLKKLSQKKFKQLVERLLQFVSLRLFPAKPEEFPPLTKCTWWIPSAAKVLALLNTANNLVHPPLVPYTDFYNSTLDHIDLMEEYHTWQSFGNSHRFSFCQYPFVISITAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPVVPSDQSTPVGICSVTIDDLCQIMPELAHGLKELLSYEGNVEEDFYSTFQVFQEEFGVIKSYNLKPGGDKIPVTNQNRREYVQLYTDFLLNKSIYKQFAAFYCGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDGYAKTDLTIRYFWDVVLGFPLELQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "length": 894 }, "evidence": [ { "id": "F1N7A0", "url": "https://omabrowser.org/oma/group/F1N7A0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZL18-1", "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2", "gene_name": "HECTD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLQSPPAAAAGLSPGAELEQEQGSAAPPAAEEDGEDEEEEEEEGEKERDKLPPIPAACGAAAGGLERGAKNQFSTFSNFITTINQKKEGTGNRNSPTQLVIPSIKNVRDLPPICLDVRQKQRISIDTLPQELKAPVPPEPSLPIRTKTVKDFQDDMEKAKSSGDWKAVHDFYSTTFDSFLEINAAFKKDANSPFNTTEDSGINAKFVNVVYDALLNTPQDVQKSVLKGIINGLLQEWKGPRTKDDLRAYCILLQNPQFSNTSTYVIYAHLLRQIAALTEADHHFLVHWSKKISQRRFKQIVDRLLQFISLRLFPAKPEEFPPMVKCTWWIPSATKVLALFNAANSLISPPIISYTDFYNSTLDHIDLMEEYHNWQCYGNSHRFSFCQHPFIISIAAKKVIIQRDSEQQMISIARQSLVDKVSRRQKPDMNMLFLNVKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGALMGLAVYNSITLDIRFPPCCYKKLLSPPIVPCDHNTLVGICDVTLDDLFQIMPELAHGLSELLSYEGNVEEDFYSTFQVFQEEFGVIKSYNLKPNGDKIPVTNQNRKEYVQLYVDFLLNKSIYKQFAAFYYGFHSVCASYALLLLRPEEVEILVCGSPELDMSALQRSTQYEGYQKTDVTIRYFWDVVLGFSLDLQKKLLHFATGSDRVPVGGMADLNFKISKSEASTSWLPVAHTCFNQLCLPPYKNKKELKQKLIIGISNAEGFGLE", "length": 794 }, "evidence": [ { "id": "F1N7A0", "url": "https://omabrowser.org/oma/group/F1N7A0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LHR3-1", "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2", "gene_name": "HECTD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEADRVPSPAAPPAVVAAAPEEKKGKEPEREKLPPIVSAGAGAAAGLDRGSKGQISTFSSFISTVNQKKEATENRSSPTHLVFPNIKNVRDLPPICLDVRQKQRVSVDALSSEMKAPVLPEPVPPVQPKTMKDFQEDVEKSKSSGDWKTVHDFYLTTFDSFPELNAAFKKDASASFNTLEDSGINAKFVNAVYDALLNTPQDIQKTVLKGIINSLLREWKGPRTKDDLRAYFILLQNPQFNNTSTYVIYAHLLRQIATLVEADHHFLVHWFKKLSQKRFKQLVERLLQFISLRLFPAKPEEFPPISKCSWWIPSTSKVLALLNTANNLVHPPLIPYTDFYNSTLDHIDLMEEYHTWQSFGNSHRFSFCQYPFVISIAAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSYCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPIVPSDQNTPVGICSVTTDDLCQIMPELAHGLSELLSYEGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKIPVTNQNRKEYVHLYIDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDGYAKTDLTIRYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "length": 776 }, "evidence": [ { "id": "F1N7A0", "url": "https://omabrowser.org/oma/group/F1N7A0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5U5R9-1", "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2", "gene_name": "HECTD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEAVRVPSPATPLVVAAPAPEERKGKESEREKLPPIVSAGAGATAGLDRGAKGQISTFSSFISAVSPKKEAAENRSSPAHLVFPNIKNVREPPPICLDVRQKQRTSMDASSSEMKAPVLPEPILPIQPKTVKDFQEDVEKVKSSGDWKAVHDFYLTTFDSFPELNAAFKKDATASFNTIEDSGINAKFVNAVYDTLLNTPQDVQKTVLKGIINSLLREWKGPRTKDDLRAYFILLQNPQFNNTSTYVIYAHLLRQIATLVEADHHFLVHWFKKLSQKRFKQLVERLLQFISLRLFPAKPEEFPPITKCSWWIPSAAKVLALLNTANNLVHPPLIPYTDFYNSTLDHIDLMEEYHTWQNFGNSHRFSFCQYPFVISVAAKKIIIQRDSEQQMINIARQSLVDKVSRRQRPDMNILFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPIIPSDQNIPVGICNVTVDDLCQIMPELAHGLSELLSHEGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPDLDMHALQRSTQYDGYAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "length": 776 }, "evidence": [ { "id": "F1N7A0", "url": "https://omabrowser.org/oma/group/F1N7A0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CDU6-1", "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2", "gene_name": "Hectd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEAARDLSPGAPPAVAAAAPEERKGKEPEREKLPPIVTAGAAAGLDRGSKGQISTFSSFVSTVTQKKEAAENRSSPTHLALPNIRNVRDLPPICLDVRQKQRMSVEALPSEVKVPPLPEPSLPSQPKTVKDFEEDLEKAEATGNWKTVHAFYITAFDSFTELNTAFKKDATASFNTIEDSGLNANLVNAVFDALLNTPQDIQKSVLKGIINSLLQEWKGPRTKDDLRAYFILLQNPQFNITSTYVIYAHLLRQIATLVEADHHFLVHWLKKLSQKKFKQLVERLLQFVSLRLFPAKPEEFPPLTKCTWWIPSAAKVLALLNTANNLVHPPLVPYTDFYNSTLDHIDLMEEYHTWQSFGNSHRFSFCQYPFVISIAAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPVVPSDQSTPVGICSVTIDDLCQVMPELAHGLKELLSYEGNVEEDFYSTFQVFQEEFGVIKSYNLKPGGDKIPVTNQNRREYVQLYTDFLLNKSIYKQFAAFYCGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDGYAKTDLTIRYFWDVVLGFPLELQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "length": 774 }, "evidence": [ { "id": "F1N7A0", "url": "https://omabrowser.org/oma/group/F1N7A0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1N7A0", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F1N7A0", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983140" } ] }, { "id": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4I9-1", "E1BJS7-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q1JQA1-1", "Q29RQ5-1", "Q32LN5-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0AAA9RXI4-1", "Q4U5R4-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983147" } ] }, { "id": "R-BTA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983156" } ] }, { "id": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLB6", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] } ] }, { "uniprot_ac": "A0A3Q1MLH2", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] } ] }, { "uniprot_ac": "A0A3Q1N3G7", "gene_name": "TRIM36", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] } ] }, { "uniprot_ac": "A0AAA9RXI4", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] } ] }, { "uniprot_ac": "A0AAA9RXX2", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] } ] }, { "uniprot_ac": "A0AAA9RZ14", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] } ] }, { "uniprot_ac": "A0AAA9S100", "gene_name": "MKRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] } ] }, { "uniprot_ac": "A0AAA9TKS8", "gene_name": "RNF217", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] } ] }, { "uniprot_ac": "A0AAA9TWH7", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] } ] }, { "uniprot_ac": "A0AAF6DMH9", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] } ] }, { "uniprot_ac": "A0ABI0NWC8", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ] }, { "uniprot_ac": "A0JN74", "gene_name": "TRIM11", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] } ] }, { "uniprot_ac": "A1A4I9", "gene_name": "UFL1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "A1A4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I9" } ] } ] }, { "uniprot_ac": "A3KN22", "gene_name": "UBE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PKG6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] } ] }, { "uniprot_ac": "A6H795", "gene_name": "UBE2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] } ] }, { "uniprot_ac": "E1B782", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] } ] }, { "uniprot_ac": "E1B7D3", "gene_name": "TRIM39", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B7Q7", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] } ] }, { "uniprot_ac": "E1B8R6", "gene_name": "ARIH2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] } ] }, { "uniprot_ac": "E1BAV2", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BBY2", "gene_name": "TRIM41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] } ] }, { "uniprot_ac": "E1BCU1", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] } ] }, { "uniprot_ac": "E1BCW1", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] } ] }, { "uniprot_ac": "E1BH71", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] } ] }, { "uniprot_ac": "E1BID7", "gene_name": "TRIM69", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] } ] }, { "uniprot_ac": "E1BIP5", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] } ] }, { "uniprot_ac": "E1BIW0", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] } ] }, { "uniprot_ac": "E1BJS7", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] } ] }, { "uniprot_ac": "E1BL26", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] } ] }, { "uniprot_ac": "E1BNQ6", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MBM6", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] } ] }, { "uniprot_ac": "F1MEX6", "gene_name": "RNF19B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MJS5", "gene_name": "HECTD3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] } ] }, { "uniprot_ac": "F1MLS5", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] } ] }, { "uniprot_ac": "F1MM41", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] } ] }, { "uniprot_ac": "F1MTS8", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] } ] }, { "uniprot_ac": "F1MWS4", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] } ] }, { "uniprot_ac": "F1MYL0", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] } ] }, { "uniprot_ac": "F1N1X8", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] } ] }, { "uniprot_ac": "F1N3I3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] } ] }, { "uniprot_ac": "F1N495", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] } ] }, { "uniprot_ac": "F1N5G3", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] } ] }, { "uniprot_ac": "F1N645", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] } ] }, { "uniprot_ac": "F1N6G5", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] } ] }, { "uniprot_ac": "F1N703", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] } ] }, { "uniprot_ac": "F1N7A0", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] } ] }, { "uniprot_ac": "P61085", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] } ] }, { "uniprot_ac": "Q0II22", "gene_name": "RNF126", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q17QG5", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] } ] }, { "uniprot_ac": "Q1JQA1", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] } ] }, { "uniprot_ac": "Q1RML1", "gene_name": "UBE2S", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] } ] }, { "uniprot_ac": "Q1RMW1", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] } ] }, { "uniprot_ac": "Q1RMX2", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] } ] }, { "uniprot_ac": "Q29RQ5", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] } ] }, { "uniprot_ac": "Q2T9X7", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] } ] }, { "uniprot_ac": "Q2TA03", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] } ] }, { "uniprot_ac": "Q2TA10", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] } ] }, { "uniprot_ac": "Q32L27", "gene_name": "UBE2Q2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] } ] }, { "uniprot_ac": "Q32LN1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] } ] }, { "uniprot_ac": "Q32LN5", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] }, { "uniprot_ac": "Q32PA5", "gene_name": "UBE2C", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q4U5R4", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] } ] }, { "uniprot_ac": "Q5E9J6", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] } ] }, { "uniprot_ac": "Q7YRV4", "gene_name": "TRIM21", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": 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322, "header": "tr|F1N7L2-1|F1N7L2_BOVIN Isoform 1 of Vomeronasal type-1 receptor OS=Bos taurus OX=9913 GN= PE=3 SV=5 CANONICAL=F1N7L2-1" }, "locus": { "chromosome": "18", "start_pos": 58343612, "end_pos": 58342035, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054942.5", "url": "https://www.ensembl.org/id/ENSBTAT00000054942.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048523.5", "url": "https://www.ensembl.org/id/ENSBTAP00000048523.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N7L2", "url": "https://www.uniprot.org/uniprotkb/F1N7L2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 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"https://www.uniprot.org/uniprotkb/F1N7L2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7L2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7L2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7L2" } ], "lectin_list": [], "domain_list": [ { 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0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "F1N7L8-1", "uniprot_ac": "F1N7L8", "uniprot_id": "F1N7L8_BOVIN", "mass": { "chemical_mass": 63002.0, "monoisotopic_mass": 63002.0 }, "refseq": { "ac": "XP_024853907", "name": "basal body-orientation factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853907" }, "gene_names": [ { "name": "BBOF1", "type": "recommended", "evidence": [ { "id": "F1N7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7L8" } ] }, { "name": "BBOF1", "type": "synonym", "evidence": [ { "id": "XP_024853907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853907" } ] } ], "protein_names": [ { "name": "Basal body-orientation factor 1", "type": "recommended", "evidence": [ { "id": "F1N7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7L8/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 176", "type": "synonym", "evidence": [ { "id": "F1N7L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7L8/entry#names_and_taxonomy" } ] }, { "name": "basal body-orientation factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024853907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853907" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7L8", "url": "https://www.uniprot.org/uniprotkb/F1N7L8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BBOF1", "url": "https://www.uniprot.org/uniprotkb/F1N7L8", "locus": { "chromosome": "10", "start_pos": 85431717, "end_pos": 85384726, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018467", "url": "https://www.ensembl.org/id/ENSBTAG00000018467" } ] } } ], "crossref": [ { "id": "F1N7L8", "url": "https://alphafold.ebi.ac.uk/entry/F1N7L8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018467", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018467", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100137993", "url": "https://www.ncbi.nlm.nih.gov/gene/100137993", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14988", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14988", "database": 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"sequence": { "sequence": "MPAKGKDKKKGKGKDKGKDKDKKKKKIIKLEESVLERAKANASLWEARLEVTELSRIEYRDTSRRLARCNEELKRQQYKMEKDTMSVLNYLKKQDQEKDNLIEKLKQQLNETKEKAQEEKEKLERKFTMQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELDDLKEDLRNTERKHQETLRRLEGKFFEEKHRLEKEAEKKIIMLADRAHHEAVVQLNNAGRSVFKENIYLQKALAYHLKEADALQKNSQKLQETQTFLSQQKEINDLLVKEKIMQLTQQKLQIQTLQKKVVSLENALVCMTKEFETEVLKLQQQAMVENQAGQVEIFKLQQLLQMKDKEMNRIKKLAKNILDERTEVERFFLDALHQVKKQILFSRKHYKQVAQTAFNLKMREACVGRMEYPKIRTFDGREHSTNSVNQDLMEADKWTDIQGNVDIGDLTWEQKEKVLRLLFAKMNGFVPRKYSQSSRPPVPDYVVPDDETTKESGDENKLQDQTFITQQVPILNSTGELLIRNIQKGSQESDTGTY", "length": 535, "header": "tr|F1N7L8-1|F1N7L8_BOVIN Isoform 1 of Basal body-orientation factor 1 OS=Bos taurus OX=9913 GN=BBOF1 PE=3 SV=4 CANONICAL=F1N7L8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P3Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Z8/entry", "sequence": { "sequence": 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376862" }, "gene_names": [ { "name": "OR10K1C", "type": "recommended", "evidence": [ { "id": "F1N7M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7M9" } ] }, { "name": "OR10K1C", "type": "synonym", "evidence": [ { "id": "NP_001376862", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376862" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 10 subfamily K member 1C", "type": "synonym", "evidence": [ { "id": "F1N7M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7M9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10K1", "type": "synonym", "evidence": [ { "id": "NP_001376862", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376862" } ] }, { "name": "olfactory receptor family 10 subfamily K member 1C", "type": "synonym", "evidence": [ { "id": "NP_001376862", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376862" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1N7M9", "url": "https://www.uniprot.org/uniprotkb/F1N7M9#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513884", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513884", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAMQMFC", "url": "https://omabrowser.org/oma/group/CAMQMFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7M9", "url": "https://www.orthodb.org/?gene=F1N7M9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376862", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376862", "database": "RefSeq", 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"Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1N7N4", "url": "https://www.uniprot.org/uniprotkb/F1N7N4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 927, "end_pos": 929, "annotation": "n_glycosylation_sequon" }, { "start_pos": 957, "end_pos": 959, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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"https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23063:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23063:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1N7P3", "url": "https://www.uniprot.org/uniprotkb/F1N7P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7P3-1", "url": "https://www.uniprot.org/uniprotkb/F1N7P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQPTLDFEPGKLDSEPAMLSSRSPPSDPESAVLSSTSPPLDSEPAMLSSTSPPLDSESAVLSSRSPPLDSEPAMLSSTSPPLDSEPAMLSSTSPPLDSEPAVVDPKAALESAFSREMNKSLFPPAVENPFVQHTHISAWRWAYIVLMGTVLVPVRVSCIAFLFIFLWPVAALSTIGCRAQPTKPAKNWRRLAQPTLKFLFQVTFFLAGFLVKVKGKKATRDEARIFVAAPHSSFFDAIACVVAGLPSVVSASQNANIPVAGKFLLSTQPVLVTRDDPNSRKTTREEILKRVTSNRQWPQILIFPEGVCTNRSCLVTFKLGAFSPGVPVQPVLLRYPNPLDTVTWTWQGFTGFQACMLTLSQPFTRVEVEFMPVYIPNVQEKKDPVLFANTVRIIMANALGVPVTDHTYEDCRLMISAGNLQLPMEAGLVEFTKISQNLKLDWDNIHQCLDKYAEIAVASKGGKIGIEEFANYLKLPISKPLQQLFALFDRNNDGTIDFREYVIGLTVLCNPVNTEKILQMSFKLFDLDKDGFITEQELAAILRAAFGVPDLDVSTLFREIAGPNSDRISYRTFKKFALKHPAYAKLFSSYLDLQAAYVYSLPQPVQA", "length": 608, "header": "tr|F1N7P3-1|F1N7P3_BOVIN Isoform 1 of EF-hand domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=5 CANONICAL=F1N7P3-1" }, "isoforms": [ { "isoform_ac": "F1N7P3-1", "url": "https://www.uniprot.org/uniprotkb/F1N7P3/entry", "sequence": { "sequence": "MAQPTLDFEPGKLDSEPAMLSSRSPPSDPESAVLSSTSPPLDSEPAMLSSTSPPLDSESAVLSSRSPPLDSEPAMLSSTSPPLDSEPAMLSSTSPPLDSEPAVVDPKAALESAFSREMNKSLFPPAVENPFVQHTHISAWRWAYIVLMGTVLVPVRVSCIAFLFIFLWPVAALSTIGCRAQPTKPAKNWRRLAQPTLKFLFQVTFFLAGFLVKVKGKKATRDEARIFVAAPHSSFFDAIACVVAGLPSVVSASQNANIPVAGKFLLSTQPVLVTRDDPNSRKTTREEILKRVTSNRQWPQILIFPEGVCTNRSCLVTFKLGAFSPGVPVQPVLLRYPNPLDTVTWTWQGFTGFQACMLTLSQPFTRVEVEFMPVYIPNVQEKKDPVLFANTVRIIMANALGVPVTDHTYEDCRLMISAGNLQLPMEAGLVEFTKISQNLKLDWDNIHQCLDKYAEIAVASKGGKIGIEEFANYLKLPISKPLQQLFALFDRNNDGTIDFREYVIGLTVLCNPVNTEKILQMSFKLFDLDKDGFITEQELAAILRAAFGVPDLDVSTLFREIAGPNSDRISYRTFKKFALKHPAYAKLFSSYLDLQAAYVYSLPQPVQA", "length": 608, "header": "tr|F1N7P3-1|F1N7P3_BOVIN Isoform 1 of EF-hand domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=5 CANONICAL=F1N7P3-1" }, "locus": { "chromosome": "3", "start_pos": 51332994, "end_pos": 51331171, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052156.5", "url": "https://www.ensembl.org/id/ENSBTAT00000052156.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048539.5", "url": "https://www.ensembl.org/id/ENSBTAP00000048539.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1N7P3", "url": "https://www.uniprot.org/uniprotkb/F1N7P3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N7P3", "url": "https://www.uniprot.org/uniprotkb/F1N7P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lysophosphatidic acid acyltransferase activity", "id": "GO:0042171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042171", "evidence": [ { "database": "UniProtKB", "id": "F1N7P3", "url": "https://www.uniprot.org/uniprotkb/F1N7P3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1N7P3", "url": "https://www.uniprot.org/uniprotkb/F1N7P3" } ], "pmid": "" }, { "name": "1-acylglycerophosphocholine O-acyltransferase activity", "id": "GO:0047184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047184", "evidence": [ { "database": "UniProtKB", "id": "F1N7P3", "url": "https://www.uniprot.org/uniprotkb/F1N7P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "F1N7P3", "url": "https://www.uniprot.org/uniprotkb/F1N7P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7P3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 608, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7P3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7P3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7P3" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 477, "end_pos": 512, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7Q7-1", "uniprot_ac": "F1N7Q7", "uniprot_id": "F1N7Q7_BOVIN", "mass": { "chemical_mass": 167443.0, "monoisotopic_mass": 167443.0 }, "refseq": { "ac": "XP_024855939", "name": "collagen alpha-2(IV) chain isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855939" }, "gene_names": [ { "name": "COL4A2", "type": "recommended", "evidence": [ { "id": "F1N7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7Q7" } ] }, { "name": "COL4A2", "type": "synonym", "evidence": [ { "id": "XP_024855939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855939" } ] } ], "protein_names": [ { "name": "Collagen type IV alpha 2 chain", "type": "synonym", "evidence": [ { "id": "F1N7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7Q7/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-2(IV) chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024855939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855939" } ] } ], "function": [ { "annotation": "Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.", "evidence": [ { "database": "UniProtKB", "id": "F1N7Q7", "url": "https://www.uniprot.org/uniprotkb/F1N7Q7#function" }, { "database": "UniProtKB", "id": "ARBA00003696", "url": "https://www.uniprot.org/uniprotkb/ARBA00003696#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7Q7", "url": "https://www.uniprot.org/uniprotkb/F1N7Q7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "COL4A2", "url": "https://www.uniprot.org/uniprotkb/F1N7Q7", "locus": { "chromosome": "12", "start_pos": 85154242, "end_pos": 84995988, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025210", "url": "https://www.ensembl.org/id/ENSBTAG00000025210" } ] } } ], "crossref": [ { "id": "ENSBTAG00000025210", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025210", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "508632", "url": "https://www.ncbi.nlm.nih.gov/gene/508632", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508632", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508632", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N7Q7", "url": "https://www.orthodb.org/?gene=F1N7Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01413", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01413", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024855939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855939", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7Q7", "url": "https://www.uniprot.org/uniprotkb/F1N7Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7Q7-1", "url": "https://www.uniprot.org/uniprotkb/F1N7Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"KMPGPRPRKGPQASGQGVAAAKQLGLFVEFSPEDVLLGVEEAEDDGDLEAELLALTGEAGTTGRKPAPKGQAPLPMAHIEKLAADCMQDVEEEEEEEGLEEDADLLTELQEVLGTDEEAGALDGDETASLGGPEEEKEQENVEPLVQAALLTAPVPAAQAGGPGLQALLEDRIRNYQEAAASAKEAGEAAKARRCERGLKTLESQLAAVRKGKKISEDEIPPPVALGRRPLVPQETTNRSPEAEPPAAPSVEPDNPSQPETSLLGSPGISAPPDSDPDPRALLLARQREYKVAALNAKRAGDLDRARELMRVGKRFAAVLEALEKGQPVDLSAMPPSPEDLKPLPQASQAPTAPSDAPPAVERMHPVMASDIPAAPVAPAEPQTVLDALQQRLNKYREAGTQARGSGDERKARMHERIAKQYQDAIRAHRAGRKVDFAELPVPPGFPPIPGLEPTVATEEDMMAATLAAAQKLASAEDTAPVEEEEDNNKPPGHLQDEPPAQAPVAKKPAQPLAPSSRSLPEPKTSSSKEVLSPSAREQLALLEARKLQYQRAALQAKRGRDLEQAKAHLRVAKSLEAQITQVRAGRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQHEKCLLFSKQFMHQGNVAETTRFEKLAQDRKQQLEILQLAQAQGLDPPSHHFELKTFQTVRIFAELNSTEMHLIVVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKNKTAVVKNTNSPEFDQLFKLNINRNHRGFRRVIQNKGIKFEIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSGQDVQMVTENWLVLEPRGL", "length": 861, "header": "tr|F1N7R5-1|F1N7R5_BOVIN Isoform 1 of Coiled-coil and C2 domain-containing protein 1B OS=Bos taurus OX=9913 GN=CC2D1B PE=1 SV=4 CANONICAL=F1N7R5-1" }, "isoforms": [ { "isoform_ac": "F1N7R5-1", "url": "https://www.uniprot.org/uniprotkb/F1N7R5/entry", "sequence": { "sequence": "KMPGPRPRKGPQASGQGVAAAKQLGLFVEFSPEDVLLGVEEAEDDGDLEAELLALTGEAGTTGRKPAPKGQAPLPMAHIEKLAADCMQDVEEEEEEEGLEEDADLLTELQEVLGTDEEAGALDGDETASLGGPEEEKEQENVEPLVQAALLTAPVPAAQAGGPGLQALLEDRIRNYQEAAASAKEAGEAAKARRCERGLKTLESQLAAVRKGKKISEDEIPPPVALGRRPLVPQETTNRSPEAEPPAAPSVEPDNPSQPETSLLGSPGISAPPDSDPDPRALLLARQREYKVAALNAKRAGDLDRARELMRVGKRFAAVLEALEKGQPVDLSAMPPSPEDLKPLPQASQAPTAPSDAPPAVERMHPVMASDIPAAPVAPAEPQTVLDALQQRLNKYREAGTQARGSGDERKARMHERIAKQYQDAIRAHRAGRKVDFAELPVPPGFPPIPGLEPTVATEEDMMAATLAAAQKLASAEDTAPVEEEEDNNKPPGHLQDEPPAQAPVAKKPAQPLAPSSRSLPEPKTSSSKEVLSPSAREQLALLEARKLQYQRAALQAKRGRDLEQAKAHLRVAKSLEAQITQVRAGRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQHEKCLLFSKQFMHQGNVAETTRFEKLAQDRKQQLEILQLAQAQGLDPPSHHFELKTFQTVRIFAELNSTEMHLIVVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKNKTAVVKNTNSPEFDQLFKLNINRNHRGFRRVIQNKGIKFEIFHKGSFFRSDKLVGTAHLKLERLENECEIREIVEVLDGRKPTGGKLEVKVRLREPLSGQDVQMVTENWLVLEPRGL", "length": 861, "header": "tr|F1N7R5-1|F1N7R5_BOVIN Isoform 1 of Coiled-coil and C2 domain-containing protein 1B OS=Bos taurus OX=9913 GN=CC2D1B PE=1 SV=4 CANONICAL=F1N7R5-1" }, "locus": { "chromosome": "3", "start_pos": 94011882, "end_pos": 93998819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021129.8", "url": "https://www.ensembl.org/id/ENSBTAT00000021129.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021129.7", "url": "https://www.ensembl.org/id/ENSBTAP00000021129.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 721, "start_aa": "Thr", "end_pos": 721, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr721", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-9668328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9668328", "resource": "Reactome", "description": "Sealing of the nuclear envelope (NE) by ESCRT-III" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1N7R5", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7R5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 861, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7R5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7R5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7R5" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 679, "end_pos": 818, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 721 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 238, "end_pos": 240 }, { "start_pos": 700, "end_pos": 702 }, { "start_pos": 744, "end_pos": 746 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7S1-1", "uniprot_ac": "F1N7S1", "uniprot_id": "F1N7S1_BOVIN", "mass": { "chemical_mass": 35874.0, "monoisotopic_mass": 35874.0 }, "refseq": {}, "gene_names": [ { "name": 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Olfactory receptor OS=Bos taurus OX=9913 GN=OR10AG1 PE=3 SV=4 CANONICAL=F1N7S1-1" }, "locus": { "chromosome": "15", "start_pos": 78600956, "end_pos": 78598068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021100.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021100.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021100.7", "url": "https://www.ensembl.org/id/ENSBTAP00000021100.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1N7S1", "url": "https://www.uniprot.org/uniprotkb/F1N7S1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LJ47", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PRT4", "url": "https://www.uniprot.org/uniprotkb/F6PRT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PRT4-1", "url": "https://www.uniprot.org/uniprotkb/F6PRT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGRLWPFLLSFLTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTLLLEEASARLLVGARGALFSLNAQDIGDGTHKEIRWEASPEMQSKCHQKGKNNQPSSIPQTECFNHVRFLQRLNATHLYTCGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEFVFSVLVRESQASAVGDDDKVYYFFTERAAEEGAGSFAQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPQYEMLRSVCSLQADTSAHTHFYAAFTLTTQWKTLEASAICRYDLAEVQAVFAGPYMEYQDGVRRWGRYEGGVPEPRPGSCITDSLRSRGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRSVRYTHLTGTPVSTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVLKEPQSVENLVISPMQHSLYVGAPSGIIQLPLSSCSRYRSCYDCILARDPYCGWDPSTHACMVTTTIANRSQSSRTALIQDMERGNRGCEGNRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQDGYRVGVDGLLVTDTQPEHSGNYGCYAEENGLRTLLASYSLTVRPATPAPAPQAPAMPGAQLAPDVRLLYVLAIAALGGLCLILASSLFYVACLRGGGRGHRRKYSLGRAGRAGGSAVQLQTVSGQCPGEDDDGDDGERAGGLEGGCLQIIPGEGTPAPPPPPPPPPPTELTNGLVTLPSRLRRMNGNSYVLLRQSNNGVPAGPCSFTEELSRILEKRKHTQLVEHLDESSV", "length": 850, "header": "tr|F6PRT4-1|F6PRT4_BOVIN Isoform 1 of Semaphorin-4G OS=Bos taurus OX=9913 GN=SEMA4G PE=3 SV=1 CANONICAL=F6PRT4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ47/entry", "sequence": { "sequence": "MWGRLWPFLLSFLTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTLLLEEASARLLVGARGALFSLNAQDIGDGTHKEWGLSQLVGTQMEKQISQSVAATTIDTTECFNHVRFLQRLNATHLYTCGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEFVFSVLVRESQASAVGDDDKVYYFFTERAAEEGAGSFAQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPQYEMLRSVCSLQADTSAHTHFYAAFTLTTQWKTLEASAICRYDLAEVQAVFAGPYMEYQDGVRRWGRYEGGVPEPRPGSCITDSLRSRGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRSVRYTHLTGTPVSTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVLKEPQSVENLVISPMQHSLYVGAPSGIIQLPLSSCSRYRSCYDCILARDPYCGWDPSTHACMVTTTIANRSQSSRTALIQDMERGNRGCEGNRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQDGYRVGVDGLLVTDTQPEHSGNYGCYAEENGLRTLLASYSLTVRPATPAPAPQAPAMPGAQLAPDVRLLYVLAIAALGGLCLILASSLFYVACLRGGGRGHRRKYSLGRAGRAGGSAVQLQTVSGQCPGEDDDGDDGERAGGLEGGCLQIIPGEGTPAPPPPPPPPPPTELTNGLVTLPSRLRRMNGNSYVLLRQSNNGVPAGPCSFTEELSRILEKRKHTQLVEHLDESSV", "length": 849, "header": "tr|A0A3Q1LJ47-1|A0A3Q1LJ47_BOVIN Computationally mapped isoform of Semaphorin-4G OS=Bos taurus OX=9913 GN=SEMA4G PE=3 SV=1 CANONICAL=F6PRT4-1" }, "locus": { "chromosome": "26", "start_pos": 21821362, "end_pos": 21812538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084676.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084676.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059311.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059311.2" } ] } }, { "isoform_ac": "F6PRT4-1", "url": "https://www.uniprot.org/uniprotkb/F6PRT4/entry", "sequence": { "sequence": "MWGRLWPFLLSFLTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTLLLEEASARLLVGARGALFSLNAQDIGDGTHKEIRWEASPEMQSKCHQKGKNNQPSSIPQTECFNHVRFLQRLNATHLYTCGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEFVFSVLVRESQASAVGDDDKVYYFFTERAAEEGAGSFAQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPQYEMLRSVCSLQADTSAHTHFYAAFTLTTQWKTLEASAICRYDLAEVQAVFAGPYMEYQDGVRRWGRYEGGVPEPRPGSCITDSLRSRGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRSVRYTHLTGTPVSTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVLKEPQSVENLVISPMQHSLYVGAPSGIIQLPLSSCSRYRSCYDCILARDPYCGWDPSTHACMVTTTIANRSQSSRTALIQDMERGNRGCEGNRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQDGYRVGVDGLLVTDTQPEHSGNYGCYAEENGLRTLLASYSLTVRPATPAPAPQAPAMPGAQLAPDVRLLYVLAIAALGGLCLILASSLFYVACLRGGGRGHRRKYSLGRAGRAGGSAVQLQTVSGQCPGEDDDGDDGERAGGLEGGCLQIIPGEGTPAPPPPPPPPPPTELTNGLVTLPSRLRRMNGNSYVLLRQSNNGVPAGPCSFTEELSRILEKRKHTQLVEHLDESSV", "length": 850, "header": "tr|F6PRT4-1|F6PRT4_BOVIN Isoform 1 of Semaphorin-4G OS=Bos taurus OX=9913 GN=SEMA4G PE=3 SV=1 CANONICAL=F6PRT4-1" }, "locus": { "chromosome": "26", "start_pos": 21821362, "end_pos": 21812538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024759.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024759.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024759.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024759.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 665, "start_aa": "Thr", "end_pos": 665, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr665", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 774, "start_aa": "Thr", "end_pos": 774, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr774", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6PRT4", "url": "https://www.uniprot.org/uniprotkb/F6PRT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F6PRT4", "url": "https://www.uniprot.org/uniprotkb/F6PRT4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F6PRT4", "url": "https://www.uniprot.org/uniprotkb/F6PRT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "F6PRT4", "url": "https://www.uniprot.org/uniprotkb/F6PRT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PRT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PRT4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 578, "end_pos": 660, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6PRT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PRT4" }, { "id": "PS51004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 511, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 665, 774 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 55, "end_pos": 57 }, { "start_pos": 609, "end_pos": 611 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": 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"snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PSM6-1", "uniprot_ac": "F6PSM6", "uniprot_id": "F6PSM6_BOVIN", "mass": { "chemical_mass": 19412.0, "monoisotopic_mass": 19412.0 }, "refseq": {}, "gene_names": [ { "name": "ISG12(B)", "type": "recommended", "evidence": [ { "id": "F6PSM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PSM6" } ] } ], "protein_names": [ { "name": "TLH29 protein-like", "type": "synonym", "evidence": [ { "id": "F6PSM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PSM6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PSM6", "url": "https://www.uniprot.org/uniprotkb/F6PSM6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ISG12(B)", "url": "https://www.uniprot.org/uniprotkb/F6PSM6", "locus": { "chromosome": "21", "start_pos": 58727004, "end_pos": 58716415, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004272", "url": "https://www.ensembl.org/id/ENSBTAG00000004272" } ] } } ], "crossref": [ { "id": "F6PSM6", "url": "https://alphafold.ebi.ac.uk/entry/F6PSM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004272", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004272", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6PSM6", "url": "https://www.orthodb.org/?gene=F6PSM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16932:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16932:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6PSM6", "url": "https://www.uniprot.org/uniprotkb/F6PSM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PSM6-1", "url": "https://www.uniprot.org/uniprotkb/F6PSM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPWAPSCQNCCQKRKKNLSSQPIRTPMALLLGRHHRGHIRDQMTLALTPETHPISTVMQGTLHTGTAAETQWKSIAGHSQGFFLSPGMTAAAVIGGVMAVRAVPELLDTVGFTRKGISPSSLAAKMMSSTARANGGGVPSGSLVSNLQSKGATGLSTPSNILLGSAGALLGALLWGSYSSSRRTQY", "length": 186, "header": "tr|F6PSM6-1|F6PSM6_BOVIN Isoform 1 of TLH29 protein-like OS=Bos taurus OX=9913 GN=ISG12(B) PE=3 SV=3 CANONICAL=F6PSM6-1" }, "isoforms": [ { "isoform_ac": "F6PSM6-1", "url": "https://www.uniprot.org/uniprotkb/F6PSM6/entry", "sequence": { "sequence": "MPWAPSCQNCCQKRKKNLSSQPIRTPMALLLGRHHRGHIRDQMTLALTPETHPISTVMQGTLHTGTAAETQWKSIAGHSQGFFLSPGMTAAAVIGGVMAVRAVPELLDTVGFTRKGISPSSLAAKMMSSTARANGGGVPSGSLVSNLQSKGATGLSTPSNILLGSAGALLGALLWGSYSSSRRTQY", "length": 186, "header": "tr|F6PSM6-1|F6PSM6_BOVIN Isoform 1 of TLH29 protein-like OS=Bos taurus OX=9913 GN=ISG12(B) PE=3 SV=3 CANONICAL=F6PSM6-1" }, "locus": { "chromosome": "21", "start_pos": 58726868, "end_pos": 58716502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005596.7", "url": "https://www.ensembl.org/id/ENSBTAT00000005596.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005596.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005596.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F6PSM6", "url": "https://www.uniprot.org/uniprotkb/F6PSM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "F6PSM6", "url": "https://www.uniprot.org/uniprotkb/F6PSM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intrinsic apoptotic signaling pathway", "id": "GO:0097193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097193", "evidence": [ { "database": "UniProtKB", "id": "F6PSM6", "url": "https://www.uniprot.org/uniprotkb/F6PSM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6PSM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 186, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6PSM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6PSM6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PU96-1", "uniprot_ac": "F6PU96", "uniprot_id": "F6PU96_BOVIN", "mass": { "chemical_mass": 92094.0, "monoisotopic_mass": 92094.0 }, "refseq": { "ac": "NP_001178086", "name": "chondroitin sulfate synthase 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178086" }, "gene_names": [ { "name": "CHSY1", "type": "recommended", "evidence": [ { "id": "F6PU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ] }, { "name": "CHSY1", "type": "synonym", "evidence": [ { "id": "NP_001178086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178086" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "F6PU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PU96/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F6PU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PU96/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate (chondroitin) synthase 1", "type": "synonym", "evidence": [ { "id": "NP_001178086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178086" } ] }, { "name": "chondroitin sulfate synthase 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001178086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178086" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHSY1", "url": "https://www.uniprot.org/uniprotkb/F6PU96", "locus": { "chromosome": "21", "start_pos": 5375159, "end_pos": 5285265, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007357", "url": "https://www.ensembl.org/id/ENSBTAG00000007357" } ] } } ], "crossref": [ { "id": "F6PU96", "url": "https://alphafold.ebi.ac.uk/entry/F6PU96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007357", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007357", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "281690", "url": "https://www.ncbi.nlm.nih.gov/gene/281690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281690", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281690", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAKNFLF", "url": "https://omabrowser.org/oma/group/PAKNFLF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6PU96", "url": "https://www.orthodb.org/?gene=F6PU96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PU96-1", "url": "https://www.uniprot.org/uniprotkb/F6PU96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRGRRAWLSVLLGLVLGFVLASRLVLPRASELKRAGPRRRASPEACRPGQAAAVPLAGGARGDARGQRLWPHGEAQDGVPRDRNFLFVGVMTAQKYLQTRAVAAFRTWSKTIPGKVEFFSSEGSDTSISIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLESFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHNSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTIQLHREIVLMSKYSNTEVHKEDLQLGIPPSFMRFQPRQREEILEWEFLTGKYLYSAADSQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEELDAKELANKINQESGSLSFLSNSLKKLVPFQLPGSKNEHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRDYRIKYPKADMQILPVSGEFSRALALEVGSSQFNNESLLFFCDVDLVFTAEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTYGSTHQLAEMWLEKNDPNYSKSSNNNGSVRTA", "length": 803, "header": "tr|F6PU96-1|F6PU96_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CHSY1 PE=3 SV=1 CANONICAL=F6PU96-1" }, "isoforms": [ { "isoform_ac": "F6PU96-1", "url": "https://www.uniprot.org/uniprotkb/F6PU96/entry", "sequence": { "sequence": "MAVRGRRAWLSVLLGLVLGFVLASRLVLPRASELKRAGPRRRASPEACRPGQAAAVPLAGGARGDARGQRLWPHGEAQDGVPRDRNFLFVGVMTAQKYLQTRAVAAFRTWSKTIPGKVEFFSSEGSDTSISIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLESFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHNSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTIQLHREIVLMSKYSNTEVHKEDLQLGIPPSFMRFQPRQREEILEWEFLTGKYLYSAADSQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEELDAKELANKINQESGSLSFLSNSLKKLVPFQLPGSKNEHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRDYRIKYPKADMQILPVSGEFSRALALEVGSSQFNNESLLFFCDVDLVFTAEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTYGSTHQLAEMWLEKNDPNYSKSSNNNGSVRTA", "length": 803, "header": "tr|F6PU96-1|F6PU96_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CHSY1 PE=3 SV=1 CANONICAL=F6PU96-1" }, "locus": { "chromosome": "21", "start_pos": 5373761, "end_pos": 5285464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009678.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009678.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009678.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009678.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:281690", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281690", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AWP7-1", "protein_name": "Hexosyltransferase", "gene_name": "CHSY1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAARGRRAWLSVLLGLVLGFVLASRLVLPRASELKRAGPRRRASPEGCRPGQAAAASQAGGARGDERGAQLWPHGPAADGGQRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVEFFSSEGSDTSIPIPIVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLENFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHNSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTIQLHREIVLMSKYSNTEIHKEDLQLGIAPSFMRFQPRQREEILEWEFLTGKYLYSAADGQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEGLDAKELADRINQESGSLSFLSNSLKKLVPFQLPGSKNEHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRDYRIKYPKADMQILPVSGEFSRALALEVGSSQFHNESLLFFCDVDLVFTAEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPRQYKMCLGSKASTYGSTQQLAEMWLEKNDPNYRRSSNNNGSVRTA", "length": 803 }, "evidence": [ { "id": "F6PU96", "url": "https://omabrowser.org/oma/group/F6PU96/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z8G8-1", "protein_name": "Hexosyltransferase", "gene_name": "CHSY1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRGRRAWLSVLLGLVLGFVLASRLVLPRASELAAAARPRRSRPLGCRPPPAAAAAAAAPLLLPQPRRPGPPAQSFLFVGVMTAQKYLRSRAVAAHRTWSKSIPGKVEFFSSEGSDTSIPIPIVPLPGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDKLENFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLRNSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTVQLHREIVLMSKYSNTEVHKEDLQLGMPPSFMRFQPRHREEILEWEFLTGKYLYSGADGQPPRRGMDSSQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYVLDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFMEHEEMDAKELASKINQDSGSLSFLSNSLKMFVPFQLSRSRVERKELKDQKINILIPLSGRFDMFARFMGNFEKTCLIPNQNVKLVVLLFNSNSNPDRAKQIDLMREYRSKYPKADMQVLPVSGEFSRALALEVGSSQFQNESLLFFCDVDLVFTTEFLQRCRANTVLGQQVYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLLRAGGFDVSIQGWGLEDVDLFNKVIQAGLKTFRSQEIGVVHVHHPVFCDPNLDPKQYKMCLGSKASTYGSTQQLAEIWFEKNDPSFGKSSNTNGSVRTA", "length": 793 }, "evidence": [ { "id": "F6PU96", "url": "https://omabrowser.org/oma/group/F6PU96/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZRM3-1", "protein_name": "Hexosyltransferase", "gene_name": "Chsy1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARGRRAWLSMLLGLVLGFVLASRLVLPRASELKRVGPRRRPNPEGCRPGQAASQPGGAPGDARGAQLWPQGSAAEGVPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVEFFSSEGSDTSIPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLESFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVILSREVLRRMAPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHSSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTIQLHREIVLMSKYSSTEIQKEDLQLGIPPSFMRFQARQREEILEWEFLTGKYLYSATEGQPPRRGMDSAQREALDDIVLQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEGLDAQELADRINQDSGSLSFLSNSLKKLVPFQLPGSKMEHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNLNVKLVILLFNSDSNPDKAKQVELMRDYRVKYPKADMQVLPVSGGFSRALALEVGSSQFSNESLLFFCDVDLVFTAEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTFGSTQQLAEMWLEKNDPSYSRGGNGSARTV", "length": 799 }, "evidence": [ { "id": "F6PU96", "url": "https://omabrowser.org/oma/group/F6PU96/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZQ11-1", "protein_name": "Chondroitin sulfate synthase 1", "gene_name": "Chsy1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARGRRAWLSMLLGLVLGFVLASRLVLPRASELKRVGPRRRPSPEGCRPGQEASQPGGARGDARGAQLWPQGSAAEGVPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVEFFSSEGSDTSIPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLESFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVILSREVLRRMAPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHSSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTIQLHREIVLMSKYSSTEIQKEDLQLGIPPSFMRFQARQREEILEWEFLTGKYLYSATDGQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKMQFVEHEELDAQELADRINQDSGSLSFLSNSLKKLVAFQLPGSKTEHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNLNVKLVILLFNSDSNPDKAKQVELMRDYRVKYPKADMQVLPVSGGFSRALALEVGSSQFNNESLLFFCDVDLVFTAEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHIHHPVVCDPNLDPKQYKMCLGSKASTFGSTQQLAEMWLEKNDPSYSKGGSHGSARTA", "length": 800 }, "evidence": [ { "id": "F6PU96", "url": "https://omabrowser.org/oma/group/F6PU96/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86X52-1", "protein_name": "Chondroitin sulfate synthase 1", "gene_name": "CHSY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARGRRAWLSVLLGLVLGFVLASRLVLPRASELKRAGPRRRASPEGCRSGQAAASQAGGARGDARGAQLWPPGSDPDGGPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVQFFSSEGSDTSVPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLENFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVIMSREVLRRMVPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHNSKIHQAITLHPNKNPPYQYRLHSYMLSRKISELRHRTIQLHREIVLMSKYSNTEIHKEDLQLGIPPSFMRFQPRQREEILEWEFLTGKYLYSAVDGQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKIQFVEHEELDAQELAKRINQESGSLSFLSNSLKKLVPFQLPGSKSEHKEPKDKKINILIPLSGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRDYRIKYPKADMQILPVSGEFSRALALEVGSSQFNNESLLFFCDVDLVFTTEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTYGSTQQLAEMWLEKNDPSYSKSSNNNGSVRTA", "length": 802 }, "evidence": [ { "id": "F6PU96", "url": "https://omabrowser.org/oma/group/F6PU96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "pmid": "" }, { "name": "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity", "id": "GO:0050510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050510", "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "pmid": "" }, { "name": "negative regulation of ossification", "id": "GO:0030279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030279", "evidence": [ { "database": "UniProtKB", "id": "F6PU96", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 797, "end_pos": 799, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-1971487", "name": "Chondroitin polymerase complex transfers GalNAc to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N783-1", "F6PU96-1", "E1B9D0-1", "E1BMM8-1" ], "evidence": [ { "id": "R-BTA-1971487", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971487" } ] }, { "id": "R-BTA-1971491", "name": "Chondroitin polymerase complex transfers GlcA to CS chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N783-1", "F6PU96-1", "E1B9D0-1", "E1BMM8-1" ], "evidence": [ { "id": "R-BTA-1971491", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1971491" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1B9D0", "gene_name": "CHPF2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1B9D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D0" } ] } ] }, { "uniprot_ac": "E1BMM8", "gene_name": "CHPF", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BMM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMM8" } ] } ] }, { "uniprot_ac": "F1N783", "gene_name": "CHSY3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F1N783", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N783" } ] } ] }, { "uniprot_ac": "F6PU96", "gene_name": "CHSY1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6PU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PU96" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6PU96-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 803, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6PU96-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6PU96" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 797, "end_pos": 799 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PWD5-1", "uniprot_ac": "F6PWD5", "uniprot_id": "F6PWD5_BOVIN", "mass": { "chemical_mass": 12672.0, "monoisotopic_mass": 12672.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Large ribosomal subunit protein uL6", "type": "recommended", "evidence": [ { "id": "F6PWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWD5/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L9", "type": "synonym", "evidence": [ { "id": "F6PWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWD5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5#function" }, { "database": "UniProtKB", "id": "ARBA00034092", "url": "https://www.uniprot.org/uniprotkb/ARBA00034092#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F6PWD5", "locus": {} } ], "crossref": [ { "id": "F6PWD5", "url": "https://alphafold.ebi.ac.uk/entry/F6PWD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047946", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047946", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KGCIVEE", "url": "https://omabrowser.org/oma/group/KGCIVEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11655:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11655:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PWD5-1", "url": "https://www.uniprot.org/uniprotkb/F6PWD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFGGEKYIHRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "length": 113, "header": "tr|F6PWD5-1|F6PWD5_BOVIN Isoform 1 of Large ribosomal subunit protein uL6 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=F6PWD5-1" }, "isoforms": [ { "isoform_ac": "F6PWD5-1", "url": "https://www.uniprot.org/uniprotkb/F6PWD5/entry", "sequence": { "sequence": "MIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFGGEKYIHRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "length": 113, "header": "tr|F6PWD5-1|F6PWD5_BOVIN Isoform 1 of Large ribosomal subunit protein uL6 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=F6PWD5-1" }, "locus": { "chromosome": "1", "start_pos": 59909822, "end_pos": 59909484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023649.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023649.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023649.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023649.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZUM9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "Rpl9-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIKGVALGFRYKMRSVDAHFPINVVIQENGSLVEIQNFLGEKYIHGVRMRTGVVCSVSQAQKDELILEGNETELVSNSAALIQQATTVKNKDIRKVLDGIHVSERGTVQQADE", "length": 113 }, "evidence": [ { "id": "F6PWD5", "url": "https://omabrowser.org/oma/group/F6PWD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F6PWD5", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6PWD5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 113, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6PWD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6PWD5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWD5" }, { "id": "PF00347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL6 alpha-beta", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 99, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PXE3-1", "uniprot_ac": "F6PXE3", "uniprot_id": "F6PXE3_BOVIN", "mass": { "chemical_mass": 45236.0, "monoisotopic_mass": 45236.0 }, "refseq": { "ac": "XP_002685513", "name": "caveolae-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685513" }, "gene_names": [ { "name": "CAVIN2", "type": "recommended", "evidence": [ { "id": "F6PXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXE3" } ] }, { "name": "CAVIN2", "type": "synonym", "evidence": [ { "id": "XP_002685513", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685513" } ] } ], "protein_names": [ { "name": "Caveolae associated protein 2", "type": "synonym", "evidence": [ { "id": "F6PXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXE3/entry#names_and_taxonomy" } ] }, { "name": "caveolae-associated protein 2", "type": "synonym", "evidence": [ { "id": "XP_002685513", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685513" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PXE3", "url": "https://www.uniprot.org/uniprotkb/F6PXE3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CAVIN2", "url": "https://www.uniprot.org/uniprotkb/F6PXE3", "locus": { "chromosome": "2", "start_pos": 80481712, "end_pos": 80494743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018497", "url": "https://www.ensembl.org/id/ENSBTAG00000018497" } ] } } ], "crossref": [ { "id": "F6PXE3", "url": "https://alphafold.ebi.ac.uk/entry/F6PXE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018497", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018497", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532333", "url": "https://www.ncbi.nlm.nih.gov/gene/532333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532333", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QMPNDQE", "url": "https://omabrowser.org/oma/group/QMPNDQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6PXE3", "url": "https://www.orthodb.org/?gene=F6PXE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15240:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15240:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002685513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685513", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6PXE3", "url": "https://www.uniprot.org/uniprotkb/F6PXE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PXE3-1", "url": "https://www.uniprot.org/uniprotkb/F6PXE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPEKAASSSPVPSSTPSPSLHLGSTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMERQSAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFAKEPVSSPGEEKEGEHADENKSLEETLHTVDLSSDDELPHDEEALEDSAEEKMEESRAERIKRSSLRKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESPAENETKSEDMPSSEMANDYEESSFAEGLSEASLTSALVEGKSMEGDAGTATSRGSDSAMDSNVDLTIVEDEEEESVVLEQAQQVRYAGDYVLASHEAERSEEEPVQPAVLQVDQTA", "length": 408, "header": "tr|F6PXE3-1|F6PXE3_BOVIN Isoform 1 of Caveolae associated protein 2 OS=Bos taurus OX=9913 GN=CAVIN2 PE=3 SV=1 CANONICAL=F6PXE3-1" }, "isoforms": [ { "isoform_ac": "F6PXE3-1", "url": "https://www.uniprot.org/uniprotkb/F6PXE3/entry", "sequence": { "sequence": "MQPEKAASSSPVPSSTPSPSLHLGSTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMERQSAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFAKEPVSSPGEEKEGEHADENKSLEETLHTVDLSSDDELPHDEEALEDSAEEKMEESRAERIKRSSLRKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESPAENETKSEDMPSSEMANDYEESSFAEGLSEASLTSALVEGKSMEGDAGTATSRGSDSAMDSNVDLTIVEDEEEESVVLEQAQQVRYAGDYVLASHEAERSEEEPVQPAVLQVDQTA", "length": 408, "header": "tr|F6PXE3-1|F6PXE3_BOVIN Isoform 1 of Caveolae associated protein 2 OS=Bos taurus OX=9913 GN=CAVIN2 PE=3 SV=1 CANONICAL=F6PXE3-1" }, "locus": { "chromosome": "2", "start_pos": 80494572, "end_pos": 80483330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024617.4", "url": "https://www.ensembl.org/id/ENSBTAT00000024617.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024617.3", "url": "https://www.ensembl.org/id/ENSBTAP00000024617.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:532333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532333", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y807-1", "protein_name": "Caveolae associated protein 2", "gene_name": "PRKCDBP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGEAAGGSAVPPPAEAAGGGQVNALTVLALLEKLVSMLESVEGQQRQMEQRQRGLEGAVKGIQGDLGKLCRSHGATGAAVEKLLEKSQKVCAHTRAVRERLERQCAQVRRLEQHHAQLLRRDRFKVLIFQEENEIPAGVFAKEPVPSITEGKEEPVDENKTLEETLHAVELSSEDDIHHEDDVGDSADEKAEESRAEKIKRTSLKKVDSLKKAFSRQNIEKKMNKISTKIVSPERREKIKKSLTVHHQKSSSSKSSPFKVPLTFTVKKSREGESPAEAEDRPADTVSTDQAENEEEMSFADMHSDMTPTTSLAEESKAVIDSLEKEARMESSVMTNNNIELSIVEDDEEYGMPLEDSSQKLYDERSKPVSGEMEESDEETTQAAVLQIDQTA", "length": 392 }, "evidence": [ { "id": "F6PXE3", "url": "https://omabrowser.org/oma/group/F6PXE3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1R665-1", "protein_name": "Caveolae-associated protein 2b", "gene_name": "cavin2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGEDAVQAERSSMVSTHENQELVVPSPSPTQSSPTHSLSQLGTGATNASAGEPSSPGPLAGGTTGTLPRDGASPTGQVNAITVLTLLDKLVNMLDTVQENQHKMEVRQVEIEGAVRGIQNDMTKLSKSHTSTSNTVSKLLEKSRKVSVHMKEVKDKMDRQAVQVKKLEANHAHLIKRNNFKVLIFQEENEIPSSVFVKEPTPLPEVEEEAPVIDANRSQEEGLQTIALSSDDEQAPEDDDEDFLAALNLESETRIEKSRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKISTKIVSQEQREKIKKSLTPNHQKNPSAKNSSFKVSPLTFSIKKNRSGDAEVEGETSAQAESAVASIELAPIESPTEDLSFKEVHSQLAPGQEEVKAAVEAMEKEVVPGILNGTAEVELSITEDVSEEYALSATLPQDTSKIEVCHNALQEEDKEEEEKENIQIEGSSLAEAAGQAEGVAVGQAS", "length": 474 }, "evidence": [ { "id": "F6PXE3", "url": "https://omabrowser.org/oma/group/F6PXE3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3IA88-1", "protein_name": "Caveolae-associated protein 2", "gene_name": "Cavin2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGEDAAQAEKFQHPNADMRQEKPSSPSPMPSSTPSPSLNLGSTDEAIRDNSQVNAVTVHTLLDKLVNMLDTVRENQHNMEQRQINLEGSVKGIQNDLTKLSKYQASTSNTVNKLLEKSRKVSAHTRAVRERLERQCVQVKRLENNHAQLLRRNHFKVLIFQEESEIPASVFVKEPVPGPAEGKEELAEENKSLEDTLHNVDLSSDDELPGDEEALEDSAEEKVGESRAEKIKRSSLRKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTPNHQKASSGKSSPFKVSPLSFGRKKVQEGESSAENDPKLEDQMQNDREEGSFTEGLSEASLPSGLAEGSAEDAEKPALKGNNSGVGSNADLTIMEDEEDDSADLQQVSYESGYMLNAEEMEGSSEKQVQPAVLHVDQTA", "length": 415 }, "evidence": [ { "id": "F6PXE3", "url": "https://omabrowser.org/oma/group/F6PXE3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LDR9-1", "protein_name": "Caveolae associated protein 2", "gene_name": "CAVIN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEDAAQAEKFQHLGLDMPQAKPASSSPVPSSTPSPSLNPGSTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMERQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPANVFVKDPVSSPAEGKEELADENRSLEDTLHTVDLSSDDELPHNEEALEDSAEEKMEESRAEKIKRSSLRKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESPAENETKSEDMPSSEIPNDHEESSFAEGLSEASLPSALVEGKSLEGDAGRAASRGSSSAMDSNIDLAIVEDEEEESVVVEQAQRVHYAGGYMQTSEEAEQSDEEPVQPAVLQVDQTA", "length": 424 }, "evidence": [ { "id": "F6PXE3", "url": "https://omabrowser.org/oma/group/F6PXE3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95810-1", "protein_name": "Caveolae-associated protein 2", "gene_name": "CAVIN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEDAAQAEKFQHPGSDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSEDLPSSEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKATSRGSNSGMDSNIDLTIVEDEEEESVALEQAQKVRYEGSYALTSEEAERSDGDPVQPAVLQVHQTS", "length": 425 }, "evidence": [ { "id": "F6PXE3", "url": "https://omabrowser.org/oma/group/F6PXE3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63918-1", "protein_name": "Caveolae-associated protein 2", "gene_name": "Cavin2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGEDAAQAEKFQHPNTDMLQEKPSSPSPMPSSTPSPSLNLGSTEEAIRDNSQVNAVTVHTLLDKLVNMLDAVRENQHNMEQRQINLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVRERLERQCVQVKRLENNHAQLLRRNHFKVLIFQEESEIPASVFVKEPVPSAAEGKEELADENKSLEETLHNVDLSSDDELPRDEEALEDSAEEKMEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTPNHQKASSGKSSPFKVSPLSFGRKKVREGESSVENETKLEDQMQEDREEGSFTEGLSEASLPSGLMEGSAEDAEKSARRGNNSAVGSNADLTIEEDEEEEPVALQQAQQVRYESGYMLNSEEMEEPSEKQVQPAVLHVDQTA", "length": 418 }, "evidence": [ { "id": "F6PXE3", "url": "https://omabrowser.org/oma/group/F6PXE3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66H98-1", "protein_name": "Caveolae-associated protein 2", "gene_name": "Cavin2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"go_terms": [ { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "F6PXE3", "url": "https://www.uniprot.org/uniprotkb/F6PXE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6PXE3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 408, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6PXE3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6PXE3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 16 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 295, "end_pos": 297 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"uniprot_ac": "F6Q268", "uniprot_id": "F6Q268_BOVIN", "mass": { "chemical_mass": 39825.0, "monoisotopic_mass": 39825.0 }, "refseq": {}, "gene_names": [ { "name": "UNG", "type": "recommended", "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q268" } ] }, { "name": "UNG1", "type": "synonym", "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q268" } ] } ], "protein_names": [ { "name": "Uracil-DNA glycosylase", "type": "recommended", "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q268/entry#names_and_taxonomy" } ] }, { "name": "3.2.2.27", "type": "synonym", "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q268/entry#names_and_taxonomy" } ] }, { "name": "UDG", "type": "synonym", "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11264:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11264:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "81455", "url": "https://www.rhea-db.org/rhea/81455", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "81459", "url": "https://www.rhea-db.org/rhea/81459", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6Q268", "url": "https://www.uniprot.org/uniprotkb/F6Q268", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q268-1", "url": "https://www.uniprot.org/uniprotkb/F6Q268-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVGASTAPRPESHLEHARAAWRQLLPTSAGAKLAGPRAARVGFFLGFGMIGQKTLYSFFSPNPARKRSACSPEPADPGTRGVAAVAQSGDVAASPAKKPRVGPEEPGTPPSSPLSPEQLIRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIRDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDVDGFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNAHGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELLQKSGKEPINWKDL", "length": 362, "header": "tr|F6Q268-1|F6Q268_BOVIN Isoform 1 of Uracil-DNA glycosylase OS=Bos taurus OX=9913 GN=UNG PE=3 SV=1 CANONICAL=F6Q268-1" }, "isoforms": [ { "isoform_ac": "F6Q268-1", "url": "https://www.uniprot.org/uniprotkb/F6Q268/entry", "sequence": { "sequence": "MRVGASTAPRPESHLEHARAAWRQLLPTSAGAKLAGPRAARVGFFLGFGMIGQKTLYSFFSPNPARKRSACSPEPADPGTRGVAAVAQSGDVAASPAKKPRVGPEEPGTPPSSPLSPEQLIRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIRDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDVDGFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNAHGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELLQKSGKEPINWKDL", "length": 362, "header": "tr|F6Q268-1|F6Q268_BOVIN Isoform 1 of Uracil-DNA glycosylase OS=Bos taurus OX=9913 GN=UNG PE=3 SV=1 CANONICAL=F6Q268-1" }, "locus": { "chromosome": "17", "start_pos": 63976196, "end_pos": 63966139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045245.4", "url": "https://www.ensembl.org/id/ENSBTAT00000045245.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042650.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042650.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], 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"database": "UniProtKB", "id": "F6Q268", "url": "https://www.uniprot.org/uniprotkb/F6Q268" } ], "pmid": "" }, { "name": "uracil DNA N-glycosylase activity", "id": "GO:0004844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004844", "evidence": [ { "database": "UniProtKB", "id": "F6Q268", "url": "https://www.uniprot.org/uniprotkb/F6Q268" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "base-excision repair, AP site formation via deaminated base removal", "id": "GO:0097510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097510", "evidence": [ { "database": "UniProtKB", "id": "F6Q268", "url": "https://www.uniprot.org/uniprotkb/F6Q268" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "81455", "name": "", "equation": "a 2'-deoxyuridine in double-stranded DNA + H2O = a 2'-deoxyribose 5'-monophosphate in double-stranded DNA + uracil", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6Q268-1" ], "evidence": [ { "id": "81455", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81455" } ] }, { "id": "81459", "name": "", "equation": "a 2'-deoxyuridine in single-stranded DNA + H2O = a 2'-deoxyribose 5'-monophosphate in single-stranded DNA + uracil", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6Q268-1" ], "evidence": [ { "id": "81459", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81459" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F6Q268", "gene_name": "UNG", "activity": [ { "ec_number": "3.2.2.27", "activity": "Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.", "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q268" } ] }, { "ec_number": "3.2.2.27", "activity": "", "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q268" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q268" }, { "id": "SM00986", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00986" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Uracil-DNA glycosylase-like", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 349, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.2.27", "ec_name": "Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.", "evidence": [ { "id": "3.2.2.27", "database": "BRENDA Enzymes", "url": 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Classification" ] }, { "id": "PTHR47966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47966:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47966:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6Q3A5", "url": "https://www.uniprot.org/uniprotkb/F6Q3A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q3A5-1", "url": "https://www.uniprot.org/uniprotkb/F6Q3A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKWLGLLGLVALSECMVIIPLRQMKTMRETLRERNLLTNFSEEHPYNLSQKAANDQNIIYHHPLRSYKDFSYIGNINIGTPPQEFQVLFDTGSSSLWVPSIYCQSSSCYKHNSFVPCNSSTFKATNKIFNTNYTATSIKGYLVYDTVRIGNLVSVAQPFGLSLKEFGFDDVPFDGILGLGYPRRTITGANPIFDNLWKQGVISEPVFAFYLSSQKENGSVVMFGGVNRAYYKGELNWVPVSQVGSWHINIDSISMNGTVVACKRGCQALLDTGTAFLRGPRGSVSKIQKLIHARPIDREHVVSCQAIGTLPPAVFTINGIDYPVPAQAYIQSLSGYCFSNFLVRPQRVNESETWILGEVFLRLYFSVFDRGNNRIGLAPAV", "length": 381, "header": "tr|F6Q3A5-1|F6Q3A5_BOVIN Isoform 1 of Pregnancy-associated glycoprotein 10 OS=Bos taurus OX=9913 GN=PAG10 PE=3 SV=1 CANONICAL=F6Q3A5-1" }, "isoforms": [ { "isoform_ac": "F6Q3A5-1", "url": "https://www.uniprot.org/uniprotkb/F6Q3A5/entry", "sequence": { "sequence": "MKWLGLLGLVALSECMVIIPLRQMKTMRETLRERNLLTNFSEEHPYNLSQKAANDQNIIYHHPLRSYKDFSYIGNINIGTPPQEFQVLFDTGSSSLWVPSIYCQSSSCYKHNSFVPCNSSTFKATNKIFNTNYTATSIKGYLVYDTVRIGNLVSVAQPFGLSLKEFGFDDVPFDGILGLGYPRRTITGANPIFDNLWKQGVISEPVFAFYLSSQKENGSVVMFGGVNRAYYKGELNWVPVSQVGSWHINIDSISMNGTVVACKRGCQALLDTGTAFLRGPRGSVSKIQKLIHARPIDREHVVSCQAIGTLPPAVFTINGIDYPVPAQAYIQSLSGYCFSNFLVRPQRVNESETWILGEVFLRLYFSVFDRGNNRIGLAPAV", "length": 381, "header": "tr|F6Q3A5-1|F6Q3A5_BOVIN Isoform 1 of Pregnancy-associated glycoprotein 10 OS=Bos taurus OX=9913 GN=PAG10 PE=3 SV=1 CANONICAL=F6Q3A5-1" }, "locus": { "chromosome": "29", "start_pos": 37560196, "end_pos": 37551949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005384.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005384.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005384.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005384.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1RID0-1", "protein_name": "Pregnancy-associated glycoprotein 3", "gene_name": "PPAG3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWLVILGLVALSECLVIIPLTKVKSIRENLREKDLLLNFLKEHPYNMIQKFGLKGSLCSPKISCLRLWNYLDMVYVGNITIGTPPQLFSVIFDTASSDLWVPSNQCHSRACVTHRSFNPTLSSTFQSSNRTVKLAPHSGLVSGLLGYDTVQIGRFKSENQAFGLSQSEPVKELENAFFDGVLGLGYPSLAIQGTTPVFDNLRKQGQIPEPVFALYLSTNTKKGSVLMIGGVDNNFFTGNLKWVPLSARNYWQITLDRITWRGVVVGCTRGCQAILDSGSAFLLGPSRQISSIQKIIQARFIENEYQVRCCARTTLADFIFTINNVQYPVPARAYIRKGSTPRRCYSNFSGGTESLGKEETWILGEVFLRLYFTVFDRGQNRIGLAIAV", "length": 389 }, "evidence": [ { "id": "F6Q3A5", "url": "https://omabrowser.org/oma/group/F6Q3A5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6Q3A5", "url": "https://www.uniprot.org/uniprotkb/F6Q3A5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F6Q3A5", "url": "https://www.uniprot.org/uniprotkb/F6Q3A5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "F6Q3A5", "url": "https://www.uniprot.org/uniprotkb/F6Q3A5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6Q3A5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 381, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6Q3A5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6Q3A5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q3A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q3A5" }, { "id": "PS51767", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A1", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 378, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q4D3-1", "uniprot_ac": "F6Q4D3", "uniprot_id": "F6Q4D3_BOVIN", "mass": { "chemical_mass": 110298.0, "monoisotopic_mass": 110298.0 }, "refseq": {}, "gene_names": [ { "name": "UBA7", "type": "recommended", "evidence": [ { "id": "F6Q4D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ] } ], "protein_names": [ { "name": "Ubiquitin like modifier activating enzyme 7", "type": "synonym", "evidence": [ { "id": "F6Q4D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBA7", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3", "locus": { "chromosome": "22", "start_pos": 50430082, "end_pos": 50420762, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012335", "url": "https://www.ensembl.org/id/ENSBTAG00000012335" } ] } } ], "crossref": [ { "id": "F6Q4D3", "url": "https://alphafold.ebi.ac.uk/entry/F6Q4D3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012335", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012335", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01491", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01491", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FVSPMQT", "url": "https://omabrowser.org/oma/group/FVSPMQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6Q4D3", "url": "https://www.orthodb.org/?gene=F6Q4D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10953", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10953", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10953:SF143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10953:SF143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00899", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00899", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09358", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09358", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1169408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-936440", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9909505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9909505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q4D3-1", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTLETSKLLDKELYSRQLYVLGLPAMQRIQGAKVLLSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLGRSRAEASQKLLAELSGAVQVSVYTGDITKDLLLDFQVVVLTASRLEEQLRVGTLCHEHGVCFLVADTRGLVGQLFCDFGENFTVQDPTEAEPLTANIQHISQGSPGILTLREEAGTHHFHTGDWVTFSGIEGMVELNGCDPRPLHVREDGTLEIGDTTAFSCYLRGGAVTEVKRAKTVSHEPLDTALLQPRVVAQSAQKVRARCLHQSFRALHKFQQLHGRPPKPWDPVDAEMVVDLAQAMGPLKGTEGEPLEEQLDEALVRTVALSSAGGLSPMAAVLGAVAAQEVLKAISGKFMPLDQWLYFDALDCLPEDGDPFPNPEDCAPRRCRYDGQTAVFGTNFQEKLSHQHYLLVGAGAVGCELLKSFALMGLGAGDGGGVTVADMDHVELSNLSRQFLFRSQDIHRKKAEVAAEATRRLNADLQVTPLNLQLDPTTEDIFGDDFFSGVNGVAAALDTFEARDYVAARCTHFLKPLLEAGTMGTRGSASVFIPHVTENYKAPSDAASEDAPDPVCTVRYIPATTEHTVQWAKGEFDDLFCESAKTINSHPQALSSPEDLVKSQKQPLLQTMRGVLTERPQTWQDCVLWAFGHWQLRFHYGITQLLRTYPPDKVQEDGTPFWSGPKQCPQPLKFDASQDMHLLYVLAAANLYAQMHGLPGSQDQTALRGLLNLLPLPDPQNLDRIFASELELDSPSGEFGCKQLHEDLKTWSKGPPLKPLTFEKDNDSNFHVDFVVAAASLRAQNYGIPVASHAETKRIVGRIIPAVVTTTAAVAGLVGLELYKVVGGPRPRHAFRHSYLHLAENYFSRWVPKAPDIQKFHHLKWTCWDRLEVPAGQPERTLESLLAHIQELQGLRVTMLLHGSALLYSAGWSEEKQTQHLSRRVTDLVKKVPGQRVLVLELGYEGEEDDTNFPRLHYKL", "length": 1001, "header": "tr|F6Q4D3-1|F6Q4D3_BOVIN Isoform 1 of Ubiquitin like modifier activating enzyme 7 OS=Bos taurus OX=9913 GN=UBA7 PE=3 SV=2 CANONICAL=F6Q4D3-1" }, "isoforms": [ { "isoform_ac": "F6Q4D3-1", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3/entry", "sequence": { "sequence": "MDTLETSKLLDKELYSRQLYVLGLPAMQRIQGAKVLLSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLGRSRAEASQKLLAELSGAVQVSVYTGDITKDLLLDFQVVVLTASRLEEQLRVGTLCHEHGVCFLVADTRGLVGQLFCDFGENFTVQDPTEAEPLTANIQHISQGSPGILTLREEAGTHHFHTGDWVTFSGIEGMVELNGCDPRPLHVREDGTLEIGDTTAFSCYLRGGAVTEVKRAKTVSHEPLDTALLQPRVVAQSAQKVRARCLHQSFRALHKFQQLHGRPPKPWDPVDAEMVVDLAQAMGPLKGTEGEPLEEQLDEALVRTVALSSAGGLSPMAAVLGAVAAQEVLKAISGKFMPLDQWLYFDALDCLPEDGDPFPNPEDCAPRRCRYDGQTAVFGTNFQEKLSHQHYLLVGAGAVGCELLKSFALMGLGAGDGGGVTVADMDHVELSNLSRQFLFRSQDIHRKKAEVAAEATRRLNADLQVTPLNLQLDPTTEDIFGDDFFSGVNGVAAALDTFEARDYVAARCTHFLKPLLEAGTMGTRGSASVFIPHVTENYKAPSDAASEDAPDPVCTVRYIPATTEHTVQWAKGEFDDLFCESAKTINSHPQALSSPEDLVKSQKQPLLQTMRGVLTERPQTWQDCVLWAFGHWQLRFHYGITQLLRTYPPDKVQEDGTPFWSGPKQCPQPLKFDASQDMHLLYVLAAANLYAQMHGLPGSQDQTALRGLLNLLPLPDPQNLDRIFASELELDSPSGEFGCKQLHEDLKTWSKGPPLKPLTFEKDNDSNFHVDFVVAAASLRAQNYGIPVASHAETKRIVGRIIPAVVTTTAAVAGLVGLELYKVVGGPRPRHAFRHSYLHLAENYFSRWVPKAPDIQKFHHLKWTCWDRLEVPAGQPERTLESLLAHIQELQGLRVTMLLHGSALLYSAGWSEEKQTQHLSRRVTDLVKKVPGQRVLVLELGYEGEEDDTNFPRLHYKL", "length": 1001, "header": "tr|F6Q4D3-1|F6Q4D3_BOVIN Isoform 1 of Ubiquitin like modifier activating enzyme 7 OS=Bos taurus OX=9913 GN=UBA7 PE=3 SV=2 CANONICAL=F6Q4D3-1" }, "locus": { "chromosome": "22", "start_pos": 50429982, "end_pos": 50421102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016365.6", "url": "https://www.ensembl.org/id/ENSBTAT00000016365.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016365.5", "url": "https://www.ensembl.org/id/ENSBTAP00000016365.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1169408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169408", "resource": "Reactome", "description": "ISG15 antiviral mechanism" }, { "id": "R-BTA-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" }, { "id": "R-BTA-936440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936440", "resource": "Reactome", "description": "Negative regulators of DDX58/IFIH1 signaling" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-BTA-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G652-1", "protein_name": "Ubiquitin-like modifier activating enzyme 7", "gene_name": "Uba7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIREAKVLLCGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQPQLAQLNEAVQISVHRGDITEDLVRGFQVVVLTDSKLEDQLNMGALCHKNRVYFLMAETRGLVGRLFCDFGEDFTVVDPTEVEPTSAAIQDISQGSPGIVTLRGGSKRPSFYDGDLVMFSDIEGMVELNSHSPQPVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVKHKPLDIALLQPCMVVQNTQEIQRAHCLHQTFHALHKFQQLHGRLPKPWDPDDAETVVWLAQDLEPLKGAKEESLDEALLRTIALSSAGSLSPMAAILGGVAAQEVLKAVSGKFMPLDQWLYFDALECLPEDETLLPSPEDCHPRNCRYDGQIAVFGTGFQEKLSYKHYLLVGAGAIGCEMLKGFALVGLGVRDNGGVTIADMDHVERSNLSRQFLFRPKDTGRPKAEVAAEAAHRLNPDLQVTSHTCPLDPTTEDIYDDDFFSRVDGVVAALDSFQARESLTESQVPCPRLWQPHPIPSTLLPGHYVAARCTHYLKPLLEAGTQGTRGSASVFVPYVTEVYKGPTSAEEAPYPVCTLRHFPSTVEHSLQWAQDEFEGLFRLSAETINDYQQTCTSSLLGTDGTGILALLQQVMGVLRTRPQTWQDCVVWALGHWQLCFRDNIVELLRKFPSDKVLEDGTLFWSGSKKCPHPLQFDPNQDTHFLYVLAAANLYARMHGLPGSQSQTALRELLTLTLLQEPDSMPQNLFSAEFGQEQLKELQETLDDWNKGPPLKPVLFGKDDSSNFHEDFVVAATDLRCQNYGILPVNRARIKQTIGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLGTFRHSYLHLAENHFIRSAPSAPAMQSFHHLEWTCWHRLTVPAGQPERTLESLLAHLQEEHGLTVRMLLHDQALLYSSGWPFEKQAQHLGLRTSSAGDRPETQAWAESSGV", "length": 992 }, "evidence": [ { "id": "F6Q4D3", "url": "https://omabrowser.org/oma/group/F6Q4D3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P41226-1", "protein_name": "Ubiquitin-like modifier-activating enzyme 7", "gene_name": "UBA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL", "length": 1012 }, "evidence": [ { "id": "F6Q4D3", "url": "https://omabrowser.org/oma/group/F6Q4D3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBK7-1", "protein_name": "Ubiquitin-like modifier-activating enzyme 7", "gene_name": "Uba7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIQEAKVLLCGLQGLGAEVAKNLVLTGVGSLTLHDPHPTCWADLAAQCFLSEESLGRNRAEASQAQLAQLNEAVQISVHSGDITEDLLQGFQVVVLTDSKLEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMTAAIQDISQGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVRHKPLDIALLQPHVVAQNTQEVQRAHCLHQAFHVLHKFQQLHGRLPKPWDPDDAETVVELAQDLEPLKGTEEESLDEALLRTIALSSAGTLSPMAAIMGGVAAQEVLKAISRKFMPLDQWLYFDALECLPEDETLLPSPEDCQPRNCRYDGQIAVFGTDLQEKLSDQHYLLVGAGAIGCEMLKVFALVGLGVRANGGVTVADMDYIERSNLSRQFLFRPKDVRRPKAEVAAAAAHRLNPDLRATPYTCPLDPTTEDIYDDSFFSRVNGVVAALDSFQARHYVAARCTHYLKPLLEAGTQGTWGSASVFVPYVTEAYRGPASDAASEDAPYPVCTLRHIPSSMEHSVQWAQDQFEGLFRLSTETINCYQQTCTSLSATDRTETLALLQQVMGVLRTRPQTWQDCVVWALGHWQLCFHDKVLEGGTQFSSGSNKCPHPLQFDPNHDMHFLYVLAAANLYARMHGLPGSQSQPALRELLTRLLESDSRPQNLFSAEHGQEQLKELQETLDDWRKGPPLKPVLFVKDDDSNFHVDFVVAATDLRCQNYGILPVNHARIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGLRSHGTFRHSYLHLAENHFIRSAPSAPAVQSFRDLKWTCWDRLKVPAVQPERTLKSLLAHLQEEHGLKVEMLLHHQALLYSSGWSSEKQAQHLCLRVTELVQHVTGWKPKPGLKVLVFELSCEGEEEEMAFPPLHYEL", "length": 977 }, "evidence": [ { "id": "F6Q4D3", "url": "https://omabrowser.org/oma/group/F6Q4D3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ], "pmid": "" }, { "name": "ISG15-protein conjugation", "id": "GO:0032020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032020", "evidence": [ { "database": "UniProtKB", "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ISG15 activating enzyme activity", "id": "GO:0019782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019782", "evidence": [ { "database": "UniProtKB", "id": "F6Q4D3", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6Q4D3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1001, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6Q4D3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6Q4D3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q4D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4D3" }, { "id": "SM00985", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00985" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-activating enzyme E1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 876, "end_pos": 997, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 475, "end_pos": 477 }, { "start_pos": 807, "end_pos": 809 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q4I8-1", "uniprot_ac": "F6Q4I8", "uniprot_id": "F6Q4I8_BOVIN", "mass": { "chemical_mass": 36824.0, "monoisotopic_mass": 36824.0 }, "refseq": {}, "gene_names": [ { "name": "INKA1", "type": "recommended", "evidence": [ { "id": "F6Q4I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8" } ] } ], "protein_names": [ { "name": "PAK4-inhibitor INKA1", "type": "recommended", "evidence": [ { "id": "F6Q4I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8/entry#names_and_taxonomy" } ] }, { "name": "Induced in neural crest by AP2-alpha protein homolog", "type": "synonym", "evidence": [ { "id": "F6Q4I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8/entry#names_and_taxonomy" } ] }, { "name": "Inka-box actin regulator 1", "type": "synonym", "evidence": [ { "id": "F6Q4I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8/entry#names_and_taxonomy" } ] }, { "name": "PAK4-inhibitor inka1", "type": "synonym", "evidence": [ { "id": "F6Q4I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "F6Q4I8", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8#function" }, { "database": "UniProtKB", "id": "ARBA00045406", "url": "https://www.uniprot.org/uniprotkb/ARBA00045406#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q4I8", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "INKA1", "url": "https://www.uniprot.org/uniprotkb/F6Q4I8", "locus": { "chromosome": "22", "start_pos": 50430208, "end_pos": 50432402, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012322", "url": "https://www.ensembl.org/id/ENSBTAG00000012322" } ] } } ], "crossref": [ { "id": "F6Q4I8", "url": "https://alphafold.ebi.ac.uk/entry/F6Q4I8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012322", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28615:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28615:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15342", 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"recommended", "evidence": [ { "id": "F6Q794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q794" } ] } ], "protein_names": [ { "name": "Proprotein convertase subtilisin/kexin type 1 inhibitor", "type": "synonym", "evidence": [ { "id": "F6Q794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q794/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q794", "url": "https://www.uniprot.org/uniprotkb/F6Q794" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCSK1N", "url": "https://www.uniprot.org/uniprotkb/F6Q794", "locus": { "chromosome": "X", "start_pos": 86939621, "end_pos": 86944297, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013250", "url": "https://www.ensembl.org/id/ENSBTAG00000013250" } ] } } ], "crossref": [ { "id": "F6Q794", "url": "https://alphafold.ebi.ac.uk/entry/F6Q794", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013250", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013250", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VWGAPRT", "url": "https://omabrowser.org/oma/group/VWGAPRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6Q794", "url": "https://www.orthodb.org/?gene=F6Q794", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15531", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15531", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15531:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15531:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07259", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07259", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6Q794", "url": "https://www.uniprot.org/uniprotkb/F6Q794", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q794-1", "url": "https://www.uniprot.org/uniprotkb/F6Q794-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWAGKGKIPQRAQPQSTAAVQGSSGAAHLPVSPPVRSPARWGSMAGSPLLHGPRAGGVGLLVLLLLGLLGPPRTLCARPVKEPRSLGAASPPLAEASGHRRFRRAAPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLRRIWGAPRTSDPALGLENDPDAPAAQLARALLRARLDPAALAAQLVPAPAPAAALRLRPPVYDDGPTGPDGEDAGDETPDLDPELLRYLLGRILTGIADTEAVAAPRRLRRAADQDTGPELPPEGVLGALLRVKRLETPAPQAPARRLLP", "length": 303, "header": "tr|F6Q794-1|F6Q794_BOVIN Isoform 1 of Proprotein convertase subtilisin/kexin type 1 inhibitor OS=Bos taurus OX=9913 GN=PCSK1N PE=4 SV=1 CANONICAL=F6Q794-1" }, "isoforms": [ { "isoform_ac": "F6Q794-1", "url": "https://www.uniprot.org/uniprotkb/F6Q794/entry", "sequence": { "sequence": "MGWAGKGKIPQRAQPQSTAAVQGSSGAAHLPVSPPVRSPARWGSMAGSPLLHGPRAGGVGLLVLLLLGLLGPPRTLCARPVKEPRSLGAASPPLAEASGHRRFRRAAPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLRRIWGAPRTSDPALGLENDPDAPAAQLARALLRARLDPAALAAQLVPAPAPAAALRLRPPVYDDGPTGPDGEDAGDETPDLDPELLRYLLGRILTGIADTEAVAAPRRLRRAADQDTGPELPPEGVLGALLRVKRLETPAPQAPARRLLP", "length": 303, "header": "tr|F6Q794-1|F6Q794_BOVIN Isoform 1 of Proprotein convertase subtilisin/kexin type 1 inhibitor OS=Bos taurus OX=9913 GN=PCSK1N PE=4 SV=1 CANONICAL=F6Q794-1" }, "locus": { "chromosome": "X", "start_pos": 86944198, "end_pos": 86939745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045038.4", "url": "https://www.ensembl.org/id/ENSBTAT00000045038.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042463.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042463.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 220, "start_aa": "Thr", "end_pos": 220, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr220", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9QXU9-1", "protein_name": "ProSAAS", "gene_name": "Pcsk1n", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGSPLLCGPRAGGVGLLVLLLLGLLRLPPTLSARPVKEPRSLSAASAPLAETSTPLRLRRAVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRAWGSPRASDPPLAPDDDPDAPAAQLARALLRARLDPAALAAQLVPAPAPAAALRPRPPVYDDGPTGPDVEDAADETPDVDPELLRYLLGRILTGSSEPEAAPAPRRLRRAVDQDLGPEVPPENVLGALLRVKRLENSSPQAPARRLLPP", "length": 260 }, "evidence": [ { "id": "F6Q794", "url": "https://omabrowser.org/oma/group/F6Q794/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QXV0-1", "protein_name": "ProSAAS", "gene_name": "Pcsk1n", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSPLLCGPRAGGVGILVLLLLGLLRLPPTLSARPVKEPRSLSAASAPLVETSTPLRLRRAVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRAWGSPRASDPPLAPDDDPDAPAAQLARALLRARLDPAALAAQLVPAPAAAPRPRPPVYDDGPTGPDVEDAGDETPDVDPELLRYLLGRILTGSSEPEAAPAPRRLRRSVDQDLGPEVPPENVLGALLRVKRLENPSPQAPARRLLPP", "length": 258 }, "evidence": [ { "id": "F6Q794", "url": "https://omabrowser.org/oma/group/F6Q794/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHG2-1", "protein_name": "ProSAAS", "gene_name": "PCSK1N", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGSPLLWGPRAGGVGLLVLLLLGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRLRRAADHDVGSELPPEGVLGALLRVKRLETPAPQVPARRLLPP", "length": 260 }, "evidence": [ { "id": "F6Q794", "url": "https://omabrowser.org/oma/group/F6Q794/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F6Q794", "url": "https://www.uniprot.org/uniprotkb/F6Q794" } ], "pmid": "" }, { "name": "endopeptidase inhibitor activity", "id": "GO:0004866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004866", "evidence": [ { "database": "UniProtKB", "id": "F6Q794", "url": "https://www.uniprot.org/uniprotkb/F6Q794" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6Q794", "url": "https://www.uniprot.org/uniprotkb/F6Q794" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "F6Q794", "url": "https://www.uniprot.org/uniprotkb/F6Q794" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F6Q794", "url": "https://www.uniprot.org/uniprotkb/F6Q794" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6Q794-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 303, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6Q794-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6Q794" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 220 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QA59-1", "uniprot_ac": "F6QA59", "uniprot_id": "F6QA59_BOVIN", "mass": { "chemical_mass": 73963.0, "monoisotopic_mass": 73963.0 }, "refseq": {}, "gene_names": [ { "name": "GALNT8", "type": "recommended", "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ] } ], "protein_names": [ { "name": "Polypeptide N-acetylgalactosaminyltransferase", "type": "recommended", "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59/entry#names_and_taxonomy" } ] }, { "name": "Protein-UDP acetylgalactosaminyltransferase", "type": "synonym", "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GALNT8", "url": "https://www.uniprot.org/uniprotkb/F6QA59", "locus": { "chromosome": "5", "start_pos": 105402375, "end_pos": 105441358, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017378", "url": "https://www.ensembl.org/id/ENSBTAG00000017378" } ] } } ], "crossref": [ { "id": "F6QA59", "url": "https://alphafold.ebi.ac.uk/entry/F6QA59", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017378", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017378", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6QA59", "url": "https://www.orthodb.org/?gene=F6QA59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QA59-1", "url": "https://www.uniprot.org/uniprotkb/F6QA59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRNVLGVLSIGLLLVFALNLLLIFYTKRIVQELILGDRQNKLHFAPSELNWTVMDRLSRLEANLQHLKQTMKLATKQSEDGICTLAMVKDEKLYPFPDRAHAKEGGFFKENPHKVLFPDSELFKKWGRDLSEAQQKKAEDLFQKFGYNVYLSDRLPLDRTLPDTRDSRCHWKQYPSQLPSLSVILIFMDEALSVIQRAITSIIQRTPPRLLKEIILVDDFSSLEFLQVCLWLAGELKADLDEKIKLYNQKCPGLLKIVRHTERRGLAAARNTGREAATADVVAILDAHIEVNVGWAEPILARIQEDRTVIISPVFDNILFDTFELIKYALAVDGFNWELWCRYDALPKAWVDLHDVTAPVRSPSIMGILAANRLFLEEIGSLDGGMLTYGGENVELSLRVWQCGGKIEVLPCSRVAHLERHHKPYSLDLRIPLKRNALRVAEIWMDEYKDMVYMAWNIPLQNSGIDFGDISSRMALRKKLKCKTFDWYLKNVYPLLKPVRSVVAYGRMKNTLDERVCLDQGAVPGNTPIMHYCHQYNSQNVYYHVTGEFYVGPLIAQRDADDRCLTDPGKGEKPTLEPCSKAVKDRLNIHWDFKPGRAVINRITKRCLEMKKDIWGGYTLVLQACTTQVWTIQYAVRNWGSD", "length": 644, "header": "tr|F6QA59-1|F6QA59_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT8 PE=3 SV=3 CANONICAL=F6QA59-1" }, "isoforms": [ { "isoform_ac": "F6QA59-1", "url": "https://www.uniprot.org/uniprotkb/F6QA59/entry", "sequence": { "sequence": "MLRRNVLGVLSIGLLLVFALNLLLIFYTKRIVQELILGDRQNKLHFAPSELNWTVMDRLSRLEANLQHLKQTMKLATKQSEDGICTLAMVKDEKLYPFPDRAHAKEGGFFKENPHKVLFPDSELFKKWGRDLSEAQQKKAEDLFQKFGYNVYLSDRLPLDRTLPDTRDSRCHWKQYPSQLPSLSVILIFMDEALSVIQRAITSIIQRTPPRLLKEIILVDDFSSLEFLQVCLWLAGELKADLDEKIKLYNQKCPGLLKIVRHTERRGLAAARNTGREAATADVVAILDAHIEVNVGWAEPILARIQEDRTVIISPVFDNILFDTFELIKYALAVDGFNWELWCRYDALPKAWVDLHDVTAPVRSPSIMGILAANRLFLEEIGSLDGGMLTYGGENVELSLRVWQCGGKIEVLPCSRVAHLERHHKPYSLDLRIPLKRNALRVAEIWMDEYKDMVYMAWNIPLQNSGIDFGDISSRMALRKKLKCKTFDWYLKNVYPLLKPVRSVVAYGRMKNTLDERVCLDQGAVPGNTPIMHYCHQYNSQNVYYHVTGEFYVGPLIAQRDADDRCLTDPGKGEKPTLEPCSKAVKDRLNIHWDFKPGRAVINRITKRCLEMKKDIWGGYTLVLQACTTQVWTIQYAVRNWGSD", "length": 644, "header": "tr|F6QA59-1|F6QA59_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT8 PE=3 SV=3 CANONICAL=F6QA59-1" }, "locus": { "chromosome": "5", "start_pos": 105441248, "end_pos": 105403379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023106.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023106.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023106.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023106.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F6QA59", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-913675", "name": "GALNTs transfer GalNAc to Mucins to form Tn antigens", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9942384" ], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M986-1", "Q07537-1", "E1BDW8-1", "E1BHN6-1", "A0AAA9T153-1", "F1N554-1", "F6QA59-1", "F6RJ62-1", "A0AAA9S1Y7-1", "E1BPR6-1", "E1B9U7-1", "A0AAA9S5W3-1", "E1BKQ9-1" ], "evidence": [ { "id": "R-BTA-913675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913675" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9942384", "participant_name": "UDP-GalNAc [Golgi lumen]", "crossref": [ { "id": "67138", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551132", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M986", "gene_name": "GALNT2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A3Q1M986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M986" } ] } ] }, { "uniprot_ac": "A0AAA9S1Y7", "gene_name": "GALNT14", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9S1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Y7" } ] } ] }, { "uniprot_ac": "A0AAA9S5W3", "gene_name": "GALNT3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9S5W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W3" } ] } ] }, { "uniprot_ac": "A0AAA9T153", "gene_name": "GALNT7", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9T153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T153" } ] } ] }, { "uniprot_ac": "E1B9U7", "gene_name": "GALNT17", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1B9U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9U7" } ] } ] }, { "uniprot_ac": "E1BDW8", "gene_name": "GALNT11", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BDW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDW8" } ] } ] }, { "uniprot_ac": "E1BHN6", "gene_name": "GALNT15", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BHN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHN6" } ] } ] }, { "uniprot_ac": "E1BKQ9", "gene_name": "GALNT5", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ] } ] }, { "uniprot_ac": "E1BPR6", "gene_name": "GALNT9", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BPR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPR6" } ] } ] }, { "uniprot_ac": "F1N554", "gene_name": "GALNT10", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F1N554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N554" } ] } ] }, { "uniprot_ac": "F6QA59", "gene_name": "GALNT8", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ] } ] }, { "uniprot_ac": "F6RJ62", "gene_name": "GALNT18", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ] } ] }, { "uniprot_ac": "Q07537", "gene_name": "GALNT1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] }, { "ec_number": "2.4.1.41", "activity": "L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] }, { "ec_number": "2.4.1.41", "activity": "", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QA59-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 644, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QA59-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QA59" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59" }, { "id": "SM00458", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ricin B lectin", "eco_id": "ECO_0000259", "start_pos": 507, "end_pos": 635, "start_aa": "Tyr", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QB70-1", "uniprot_ac": "F6QB70", "uniprot_id": "F6QB70_BOVIN", "mass": { "chemical_mass": 32983.0, "monoisotopic_mass": 32983.0 }, "refseq": {}, "gene_names": [ { "name": "TREX1", "type": "recommended", "evidence": [ { "id": "F6QB70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ] } ], "protein_names": [ { "name": "exodeoxyribonuclease III", "type": "recommended", "evidence": [ { "id": "F6QB70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QB70/entry#names_and_taxonomy" } ] }, { "name": "3.1.11.2", "type": "synonym", "evidence": [ { "id": "F6QB70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QB70/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TREX1", "url": "https://www.uniprot.org/uniprotkb/F6QB70", "locus": { "chromosome": "22", "start_pos": 51399383, "end_pos": 51400910, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008406", "url": "https://www.ensembl.org/id/ENSBTAG00000008406" } ] } } ], "crossref": [ { "id": "F6QB70", "url": "https://alphafold.ebi.ac.uk/entry/F6QB70", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13058", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13058", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13058:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13058:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QB70-1", "url": "https://www.uniprot.org/uniprotkb/F6QB70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VSLPATAAAGSKNQAESVHPESLLPAGSSPKITELCLLAVHRYALEGLSAPQGPSPTAPVPPRVLDKLSLCVAPGKVCSPAASEITGLSTAVLAAHGRRAFDADLVNLIRTFLQRQPQPWCLVAHNGDRYDFPLLRAELALLGLASALDDAFCVDSITALKALEPTGSSSEHGPRKSYSLGSVYTRLYGQAPPDSHTAEGDVLALLSVCQWRPRALLRWVDAHAKPFSTVKPMYVITTSTGTNPRPSAVTATVPLARASDTGPNLRGDRSPKPAPSPKMCPGAPPGEGLLAPLGLLAFLTLAVAMLYGLSLAMPGQ", "length": 316, "header": "tr|F6QB70-1|F6QB70_BOVIN Isoform 1 of exodeoxyribonuclease III OS=Bos taurus OX=9913 GN=TREX1 PE=3 SV=1 CANONICAL=F6QB70-1" }, "isoforms": [ { "isoform_ac": "F6QB70-1", "url": "https://www.uniprot.org/uniprotkb/F6QB70/entry", "sequence": { "sequence": "VSLPATAAAGSKNQAESVHPESLLPAGSSPKITELCLLAVHRYALEGLSAPQGPSPTAPVPPRVLDKLSLCVAPGKVCSPAASEITGLSTAVLAAHGRRAFDADLVNLIRTFLQRQPQPWCLVAHNGDRYDFPLLRAELALLGLASALDDAFCVDSITALKALEPTGSSSEHGPRKSYSLGSVYTRLYGQAPPDSHTAEGDVLALLSVCQWRPRALLRWVDAHAKPFSTVKPMYVITTSTGTNPRPSAVTATVPLARASDTGPNLRGDRSPKPAPSPKMCPGAPPGEGLLAPLGLLAFLTLAVAMLYGLSLAMPGQ", "length": 316, "header": "tr|F6QB70-1|F6QB70_BOVIN Isoform 1 of exodeoxyribonuclease III OS=Bos taurus OX=9913 GN=TREX1 PE=3 SV=1 CANONICAL=F6QB70-1" }, "locus": { "chromosome": "22", "start_pos": 51400781, "end_pos": 51399438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011063.4", "url": "https://www.ensembl.org/id/ENSBTAT00000011063.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011063.3", "url": "https://www.ensembl.org/id/ENSBTAP00000011063.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "DNA binding, bending", "id": "GO:0008301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008301", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0008311", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" }, { "name": "MutLalpha complex binding", "id": "GO:0032405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032405", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" }, { "name": "MutSalpha complex binding", "id": "GO:0032407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032407", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" }, { "name": "adenyl deoxyribonucleotide binding", "id": "GO:0032558", "url": 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"GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" }, { "name": "negative regulation of cGAS/STING signaling pathway", "id": "GO:0160049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160049", "evidence": [ { "database": "UniProtKB", "id": "F6QB70", "url": "https://www.uniprot.org/uniprotkb/F6QB70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QB70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QB70" }, { "id": "SM00479", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00479" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exonuclease", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 218, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.11.2", "ec_name": "Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.", "evidence": [ { "id": "3.1.11.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.11.2" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QDV4-1", "uniprot_ac": "F6QDV4", "uniprot_id": "F6QDV4_BOVIN", "mass": { "chemical_mass": 28517.0, "monoisotopic_mass": 28517.0 }, "refseq": { "ac": "NP_001178298", "name": "uroporphyrinogen-III synthase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" }, "gene_names": [ { "name": "UROS", "type": "recommended", "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ] }, { "name": "UROIIIS", "type": "synonym", "evidence": [ { "id": "NP_001178298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" } ] }, { "name": "UROS", "type": "synonym", "evidence": [ { "id": "NP_001178298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" } ] } ], "protein_names": [ { "name": "Uroporphyrinogen-III synthase", "type": "recommended", "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.75", "type": "synonym", "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4/entry#names_and_taxonomy" } ] }, { "name": "Hydroxymethylbilane hydrolyase [cyclizing]", "type": "synonym", "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4/entry#names_and_taxonomy" } ] }, { "name": "Uroporphyrinogen-III cosynthase", "type": "synonym", "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4/entry#names_and_taxonomy" } ] }, { "name": "hydroxymethylbilane hydrolyase, cyclizing", "type": "synonym", "evidence": [ { "id": "NP_001178298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" } ] }, { "name": "uroporphyrinogen III synthase (congenital erythropoietic porphyria)", "type": "synonym", "evidence": [ { "id": "NP_001178298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" } ] }, { "name": "uroporphyrinogen-III cosynthetase", "type": "synonym", "evidence": [ { "id": "NP_001178298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" } ] }, { "name": "uroporphyrinogen-III synthase", "type": "synonym", "evidence": [ { "id": "NP_001178298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" } ] } ], "function": [ { "annotation": "Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).", "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4#function" }, { "database": "UniProtKB", "id": "ARBA00060039", "url": "https://www.uniprot.org/uniprotkb/ARBA00060039#function" } ] }, { "annotation": "Study substantiated that insufficient activity of UROS is the cause of CEP in the family studied here. and provided strong evidence for LD between markers within the region and the phenotype.", "evidence": [ { "database": "RefSeq", "id": "NP_001178298", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" }, { "database": "PubMed", "id": "22404357", "url": "https://glygen.org/publication/PubMed/22404357" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UROS", "url": "https://www.uniprot.org/uniprotkb/F6QDV4", "locus": { "chromosome": "26", "start_pos": 45300454, "end_pos": 45324617, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005791", "url": "https://www.ensembl.org/id/ENSBTAG00000005791" } ] } } ], "crossref": [ { "id": "F6QDV4", "url": "https://alphafold.ebi.ac.uk/entry/F6QDV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005791", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005791", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613425", "url": "https://www.ncbi.nlm.nih.gov/gene/613425", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613425", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613425", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHGADTG", "url": "https://omabrowser.org/oma/group/IHGADTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QDV4", "url": "https://www.orthodb.org/?gene=F6QDV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12390:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12390:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-189451", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178298", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "18965", "url": "https://www.rhea-db.org/rhea/18965", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LK40", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK40-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QDV4-1", "url": "https://www.uniprot.org/uniprotkb/F6QDV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVLLLKDPKEDDCGQDPYVRELGLYGLEATLIPVLSFEFLSLPSLSEKLSHPEGYGGLIFTSPRAVEAVERCLQKDTKAEVWKKSLKEKWNAKSVYVVGNATASLVNRIGLHTEGETCGNAEKLAEYICSREPSALPLLFPCGTLKREILPKMLKDKGIPLESVTVYQTIPHPGIQGNLTSYYTQQGVPASITFFSPSGLTHSLKHIQELSGDSIGQIKFVAIGPTTAQALAAQGLPVSCTAESPTPRALAAGIRTTLQPHAC", "length": 264, "header": "tr|F6QDV4-1|F6QDV4_BOVIN Isoform 1 of Uroporphyrinogen-III synthase OS=Bos taurus OX=9913 GN=UROS PE=3 SV=1 CANONICAL=F6QDV4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK40-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK40/entry", "sequence": { "sequence": "VAGPGCQCACASFGAGPLDPPPRVQVTSNSGRGLGLSSWQRWPRGKGAALGSALSVAAGQPAGGNLESPPRRGLLLSASPAPPGRCRLCTVPAKTQDFRGRTGTRLWKKSLKEKWNAKSVYVVGNATASLVNRIGLHTEGETCGNAEKLAEYICSREPSALPLLFPCGTLKREILPKMLKDKGIPLESVTVYQTIPHPGIQGNLTSYYTQQGVPASITFFSPSGLTHSLKHIQELSGDSIGQIKFVAIGPTTAQALAAQGLPVSCTAESPTPRALAAGIRTTLQPHAC", "length": 288, "header": "tr|A0A3Q1LK40-1|A0A3Q1LK40_BOVIN Computationally mapped isoform of Uroporphyrinogen III synthase OS=Bos taurus OX=9913 GN=UROS PE=4 SV=1 CANONICAL=F6QDV4-1" }, "locus": { "chromosome": "26", "start_pos": 45324418, "end_pos": 45300971, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070931.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070931.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059895.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059895.2" } ] } }, { "isoform_ac": "F6QDV4-1", "url": "https://www.uniprot.org/uniprotkb/F6QDV4/entry", "sequence": { "sequence": "MKVLLLKDPKEDDCGQDPYVRELGLYGLEATLIPVLSFEFLSLPSLSEKLSHPEGYGGLIFTSPRAVEAVERCLQKDTKAEVWKKSLKEKWNAKSVYVVGNATASLVNRIGLHTEGETCGNAEKLAEYICSREPSALPLLFPCGTLKREILPKMLKDKGIPLESVTVYQTIPHPGIQGNLTSYYTQQGVPASITFFSPSGLTHSLKHIQELSGDSIGQIKFVAIGPTTAQALAAQGLPVSCTAESPTPRALAAGIRTTLQPHAC", "length": 264, "header": "tr|F6QDV4-1|F6QDV4_BOVIN Isoform 1 of Uroporphyrinogen-III synthase OS=Bos taurus OX=9913 GN=UROS PE=3 SV=1 CANONICAL=F6QDV4-1" }, "locus": { "chromosome": "26", "start_pos": 45316041, "end_pos": 45300971, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007615.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007615.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007615.5", "url": "https://www.ensembl.org/id/ENSBTAP00000007615.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 227, "start_aa": "Thr", "end_pos": 227, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr227", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 247, "start_aa": "Thr", "end_pos": 247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A molecular study of congenital erythropoietic porphyria in cattle.", "journal": "Animal genetics", "date": "2012-04", "authors": "Agerholm J S, Thulstrup P W, Bjerrum M J, Bendixen C, J\u00f8rgensen C B, Fredholm M", "evidence": [ { "database": "RefSeq", "id": "NP_001178298", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178298" } ], "reference": [ { "type": "PubMed", "id": "22404357", "url": "https://glygen.org/publication/PubMed/22404357" } ] } ], "pathway": [ { "id": "bta:613425", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613425", "resource": "KEGG Pathway" }, { "id": "R-BTA-189451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189451", "resource": "Reactome", "description": "Heme biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BUH1-1", "protein_name": "Uroporphyrinogen-III synthase", "gene_name": "UROS", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKVLLLKDPKDKESGPDPYVKELGLYGFEATLIPVLSFEFVSLEGLFEKQLSHPECYGGLVFTSPRALEAIKICLRENSKNEAWSKSLKQQWNAKPTYVVGKATASLVEEIGLCPQGEKSGNAEKLAEYICSREGPHSSPLLFPCGALKREVLPTALKEKGIPLESLTVYQTAQHEHLQQSLSSYFSQQGVPASIVFFSPSGVKFCLQHIQKLSGDFANRIKFAAIGPTTAEAMEAAGIPVSCTAESPTPQDLTAGIQKALRPQNCILSE", "length": 270 }, "evidence": [ { "id": "F6QDV4", "url": "https://omabrowser.org/oma/group/F6QDV4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3IGN6-1", "protein_name": "Uroporphyrinogen-III synthase", "gene_name": "Uros", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKVLLLKDAKDDDSGQDPYIQELGLYGLEATLIPVLSFEFLSLPSLSEKLSHPEGFGGLIFTSPRAVEAVKLSLEQDNKTEEWEKSLKNKWNAKSVYVVGNATACLVNKIGLDAEGAHSGNAEKLAEYICSRPSSALPLLFPCGTIKGDTLPKMLKDKGIPMESMHVYQTVPHPGIQGNLESFYENQGIPASITFFSPSGLKYSLEYIQVLSGDSFDQIKFVAIGPSTTRAMAAKGLPVSCTAESPTPQALAAGIRKVLQPNTCC", "length": 265 }, "evidence": [ { "id": "F6QDV4", "url": "https://omabrowser.org/oma/group/F6QDV4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P06174-1", "protein_name": "Uroporphyrinogen-III synthase", "gene_name": "HEM4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSRKKVRVLLLKNKTVPIDKYELECRSKAFEPIFVPLIKHTHVIQDFRNVLNTIPNYLNTINYIIITSQRTVESLNEAIIPTLTSEQKAALLSKTVYTVGPATANFIRRSGFINVKGGEDAGNGSILADIIIDDLSTDIKACPPSELLFLVGEIRRDIIPKKLHSKGIKVREVVTYKTEELSDGFKRFIHAMKECDEDEVFSDWVVVFSPQGTKEITQYLGDSNRLPGSHLRVASIGPTTKKYLDDNDVTSDVVSPKPDPKSLLDAIELYQRHK", "length": 275 }, "evidence": [ { "id": "F6QDV4", "url": "https://omabrowser.org/oma/group/F6QDV4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P10746-1", "protein_name": "Uroporphyrinogen-III synthase", "gene_name": "UROS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC", "length": 265 }, "evidence": [ { "id": "F6QDV4", "url": "https://omabrowser.org/oma/group/F6QDV4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51163-1", "protein_name": "Uroporphyrinogen-III synthase", "gene_name": "Uros", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVLLLKDAKEDDSGLDPYIQELRLCGLEATLIPVLSFEFMSLPSLSEKLSHPEGFGGLIFTSPRAVEAVKLCLEKDNKTEAWEKSLKDRWNAKSVYVVGSATASLVNKIGLDAEGAGSGNAEKLAEYICSKPSSELPLLFPCGTIKGDTLPKMLKDKGIPMESMHVYQTVPHPGIQGSLKSYYEDQGIPASITFFSPSGLKYSLEYIQALSGSSFDQIKFIAIGPSTTRAMAAKGLPVSCTAESPTPQALAAGIRNVLKPNHCC", "length": 265 }, "evidence": [ { "id": "F6QDV4", "url": "https://omabrowser.org/oma/group/F6QDV4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XIF2-1", "protein_name": "Uroporphyrinogen-III synthase", "gene_name": "Uros", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVLLLKDAKDDDSGQDPYIQELRLCGLEATLIPVLSFEFMSLPSLSEKLSHPEGFGGLIFTSPRAVEAVKLCLEKDNKTEAWEKSLKDRWNAKSVYVVGSATASLGEESQKDEVNKIGLDAEGAGSGNAEKLAEYICSKPSSELPLLFPCGTIKGDTLPKMLRDKGIPMESMHVYQTIPHPGIQGSLESYYENQGIPASITFFSPSGLKYSLEYIQALSGGSFDQIKFVAIGPSTTRAMAAKGLPVSCTAESPTPQALAAGIRKALKPNSCC", "length": 273 }, "evidence": [ { "id": "F6QDV4", "url": "https://omabrowser.org/oma/group/F6QDV4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9W3B3-1", "protein_name": "Uroporphyrinogen-III synthase", "gene_name": "Uros1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSRQRTVIIFKSESESSDVYAETLEKHDFNPVFVPTLSFGFKNLDELRAKLQNPDKYAGIIFTSPRCVEAVAESLNLGELPGGWKMLHNYAVGEVTHNLALSTLDQLFTHGKQTGNARALGDYIVDTFDGSRALPLLLPCGNLATDTLLSKLAENGFSVDACEVYETRCHPELGANVERALEIYGESIEFLAFFSPSGVNCAQQYFTSRQLSMDKWKLVAIGPSTRRALESLGQKVYCTAERPTVEHLVKVLLNPQDSRERLLKERERMAAIENNN", "length": 277 }, "evidence": [ { "id": "F6QDV4", "url": "https://omabrowser.org/oma/group/F6QDV4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protoporphyrinogen IX biosynthetic process", "id": "GO:0006782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006782", "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ], "pmid": "" }, { "name": "uroporphyrinogen III biosynthetic process", "id": "GO:0006780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006780", "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ], "pmid": "" }, { "name": "heme B biosynthetic process", "id": "GO:0006785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006785", "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ], "pmid": "" }, { "name": "heme A biosynthetic process", "id": "GO:0006784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006784", "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "uroporphyrinogen-III synthase activity", "id": "GO:0004852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004852", "evidence": [ { "database": "UniProtKB", "id": "F6QDV4", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18965", "name": "", "equation": "hydroxymethylbilane = uroporphyrinogen III + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QDV4-1" ], "evidence": [ { "id": "18965", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18965" } ] }, { "id": "R-BTA-189488", "name": "UROS transforms HMB to URO3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-189449" ], "output_participant_list": [], "enzyme_list": [ "F6QDV4-1" ], "evidence": [ { "id": "R-BTA-189488", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189488" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-189449", "participant_name": "HMBL [cytosol]", "crossref": [ { "id": "57845", "database": "ChEBI", "url": "" }, { "id": "ZINC000096014964", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F6QDV4", "gene_name": "UROS", "activity": [ { "ec_number": "4.2.1.75", "activity": "hydroxymethylbilane = uroporphyrinogen III + H2O.", "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ] }, { "ec_number": "4.2.1.75", "activity": "", "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QDV4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 264, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QDV4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QDV4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QDV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDV4" }, { "id": "PF02602", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02602" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetrapyrrole biosynthesis uroporphyrinogen III synthase", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 252, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.75", "ec_name": "hydroxymethylbilane = uroporphyrinogen III + H2O.", "evidence": [ { "id": "4.2.1.75", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.75" }, { "id": "4.2.1.75", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.75" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 227, 247 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 179, "end_pos": 181 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] 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"https://www.uniprot.org/uniprotkb/F6QIL4/entry", "sequence": { "sequence": "MSECVSTIYSPLSSQGPMSKLWRRGSTSGAMEAPEPGEALELSLAGAHGHGVHKKKHKKHKKKHKKKHYQEEEAGPTQQSPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPVEGVPLEQYRAWLDEDSNLSPSPLRDLSGGLGGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQRALLQKARSQPSPMLSLPVAGGCPAPALTEEMLLKREERARKRRLQAARRAEEHKNQTIERLTKTAAPSGRGGRGASRGERRGGRAVAPAPMVRYSSGAQGSTLSFPPGIPAPAPVSQRPSPSGPPPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQMRLGGPEGPGSPLLAT", "length": 373, "header": "tr|F6QIL4-1|F6QIL4_BOVIN Isoform 1 of INO80 complex subunit B OS=Bos taurus OX=9913 GN=INO80B PE=4 SV=1 CANONICAL=F6QIL4-1" }, "locus": { "chromosome": "11", "start_pos": 10173722, "end_pos": 10171053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002404.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002404.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002404.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002404.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689603", "resource": "Reactome", "description": "UCH proteinases" }, { "id": "R-BTA-5696394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696394", "resource": "Reactome", "description": "DNA Damage Recognition in GG-NER" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SLH2-1", "protein_name": "INO80 complex subunit B", "gene_name": "INO80B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKLWRRGSTSGAMEAPEPGEALELSLAGAHGHGVHKKKHKKHKKKHKKKHYQEEEAGPTQPSPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPMEGVPLEQYRAWLDEDSNLSPSPLRDLSGSLGGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQRALLQKARSQPSPMLSLPVAGGCPAPALTEEMLLKREERARKRRLQAARRAEEHKNQTIERLTKTAAPSGRGGRGAARGERRGGRTAAPAPMVRYSSGAQGSTLSFPPGVPAPAPVSQRPSPSGPPPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQMRLGGPEGPGSPLLAT", "length": 356 }, "evidence": [ { "id": "F6QIL4", "url": "https://omabrowser.org/oma/group/F6QIL4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7FBV1-1", "protein_name": "INO80 complex subunit B", "gene_name": "Ino80b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSACVPTVSSPLPLQDPMSKLWRRGSTSGAMEPPEPGETLELSLAGAHGHGVHKKKHKKHKKKHKKKHHQEEEAGPTLQAPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPMEGVPLEQYRAWLDEDSNLSPSPLRDLPGDLEGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQRALLQKARSQPSPTLPLPVAGGCPAPALTEEMLLKREERARKRRLQAARRAEEHKNQTIERLTKTAAPSGRGGRGAARGERRGGRAAAPAPAPMVRYSSGAQGSTLSFPPGVPTPAAVAQRPAPSGPAPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQLRLGGPEGPGSPLLAT", "length": 375 }, "evidence": [ { "id": "F6QIL4", "url": "https://omabrowser.org/oma/group/F6QIL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99PT3-1", "protein_name": "INO80 complex subunit B", "gene_name": "Ino80b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSACVPTVSSPLPLQDPMSKLWRRGSTSGAMEAPEPGETLELSLAGAHGHGVHKKKHKKHKKKHKKKHHQEEEAGPTLQTPAKPQLKLKIKLGGQVLGTKSVPTFTVIPEGPRSPSPLMVVDNEEEPMEGVPLEQYRAWLDEDSNLSPSPLRDLPGDLEGQEEEEEQRWLDALEKGELDDNGDLKKEINERLLTARQRALLQKARSQPSPTLPLPVGGGCPAPALTEEMLLKREERARKRRLQAARRAEEHKNQTIERLTKTAAPSGRGGRGAARGERRGGRAAAPAPAPMVRYCSGAQGSTLSFPPGVPTPTAVAQRPAPSGPAPRCSVPGCPHPRRYACSRTGQALCSLQCYRINLQLRLGGPEGPGSPLLAT", "length": 375 }, "evidence": [ { "id": "F6QIL4", "url": "https://omabrowser.org/oma/group/F6QIL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C086-1", "protein_name": "INO80 complex subunit B", "gene_name": "INO80B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F6QIL4", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QIL4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 373, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QIL4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QIL4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QIL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIL4" }, { "id": "SM01406", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "INO80 complex subunit B-like conserved region", "eco_id": "ECO_0000259", "start_pos": 228, "end_pos": 307, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 253, "end_pos": 255 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QIZ6-1", "uniprot_ac": "F6QIZ6", "uniprot_id": "F6QIZ6_BOVIN", "mass": { "chemical_mass": 77271.0, "monoisotopic_mass": 77271.0 }, "refseq": {}, "gene_names": [ { "name": "TUBGCP4", "type": "recommended", "evidence": [ { "id": "F6QIZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ] } ], "protein_names": [ { "name": "Gamma-tubulin complex component", "type": "recommended", "evidence": [ { "id": "F6QIZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.", "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6#function" }, { "database": "UniProtKB", "id": "ARBA00093416", "url": "https://www.uniprot.org/uniprotkb/ARBA00093416#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TUBGCP4", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6", "locus": { "chromosome": "21", "start_pos": 55164325, "end_pos": 55122674, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014479", "url": "https://www.ensembl.org/id/ENSBTAG00000014479" } ] } } ], "crossref": [ { "id": "F6QIZ6", "url": "https://alphafold.ebi.ac.uk/entry/F6QIZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19302:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19302:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QIZ6-1", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPSQQGQGGSHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQDLVVLLVPRAFTLQRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKEHKDAPQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQSDAVKWRLRNRMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM", "length": 678, "header": "tr|F6QIZ6-1|F6QIZ6_BOVIN Isoform 1 of Gamma-tubulin complex component OS=Bos taurus OX=9913 GN=TUBGCP4 PE=3 SV=1 CANONICAL=F6QIZ6-1" }, "isoforms": [ { "isoform_ac": "F6QIZ6-1", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6/entry", "sequence": { "sequence": "MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPSQQGQGGSHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLADPHLSISHVNYSLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQDLVVLLVPRAFTLQRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKEHKDAPQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQSDAVKWRLRNRMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM", "length": 678, "header": "tr|F6QIZ6-1|F6QIZ6_BOVIN Isoform 1 of Gamma-tubulin complex component OS=Bos taurus OX=9913 GN=TUBGCP4 PE=3 SV=1 CANONICAL=F6QIZ6-1" }, "locus": { "chromosome": "21", "start_pos": 55163541, "end_pos": 55122874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019254.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019254.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019254.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019254.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "F6QIZ6", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QIZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" }, { "id": "PF04130", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04130" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gamma tubulin complex component C-terminal", "eco_id": "ECO_0000259", "start_pos": 362, "end_pos": 666, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QIZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIZ6" }, { "id": "PF17681", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17681" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gamma tubulin complex component protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 359, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 560, "end_pos": 562 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QJG7-1", "uniprot_ac": "F6QJG7", "uniprot_id": "F6QJG7_BOVIN", "mass": { "chemical_mass": 35896.0, "monoisotopic_mass": 35896.0 }, "refseq": {}, "gene_names": [ { "name": "ZPBP2", "type": "recommended", "evidence": [ { "id": "F6QJG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJG7" } ] } ], "protein_names": [ { "name": "Zona pellucida binding protein 2", "type": "synonym", "evidence": [ { "id": "F6QJG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QJG7", "url": "https://www.uniprot.org/uniprotkb/F6QJG7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZPBP2", "url": "https://www.uniprot.org/uniprotkb/F6QJG7", "locus": { "chromosome": "19", "start_pos": 40227149, "end_pos": 40217412, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030523", "url": "https://www.ensembl.org/id/ENSBTAG00000030523" } ] } } ], "crossref": [ { "id": "F6QJG7", "url": "https://alphafold.ebi.ac.uk/entry/F6QJG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030523", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030523", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KSCVGKY", "url": "https://omabrowser.org/oma/group/KSCVGKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QJG7", "url": "https://www.orthodb.org/?gene=F6QJG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15443:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15443:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6QJG7", "url": "https://www.uniprot.org/uniprotkb/F6QJG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QJG7-1", "url": "https://www.uniprot.org/uniprotkb/F6QJG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAWVLLSAVLWYLTGVGWQRNSERTEKGFIYGKPGHPVKVYVKLHHNSPVLVCMDFKRAEKETVDPTYLWVGPNEKQLSGSNRINITNTGKLTVKDFLEPLSGLYTCSFSYKTIKAETQEEKIVKQRYDFMIFAYREPDYSYQMAVRFTTKSCVGKYNDLLFRVLKKILDNLIFDLSCHIIEPSYKCHFVKVPKHGLIHELFIAFQVNPFAPGWKGTCNESTDCEDTTNHNILQARNRIEEFFRSQAYIFNHDLNKTLPAMHFVDHSFQIWFVVLGLLVLMLMLHVRPAFPSKSTELNHASKFQHED", "length": 308, "header": "tr|F6QJG7-1|F6QJG7_BOVIN Isoform 1 of Zona pellucida binding protein 2 OS=Bos taurus OX=9913 GN=ZPBP2 PE=4 SV=2 CANONICAL=F6QJG7-1" }, "isoforms": [ { "isoform_ac": "F6QJG7-1", "url": "https://www.uniprot.org/uniprotkb/F6QJG7/entry", "sequence": { "sequence": "MRAWVLLSAVLWYLTGVGWQRNSERTEKGFIYGKPGHPVKVYVKLHHNSPVLVCMDFKRAEKETVDPTYLWVGPNEKQLSGSNRINITNTGKLTVKDFLEPLSGLYTCSFSYKTIKAETQEEKIVKQRYDFMIFAYREPDYSYQMAVRFTTKSCVGKYNDLLFRVLKKILDNLIFDLSCHIIEPSYKCHFVKVPKHGLIHELFIAFQVNPFAPGWKGTCNESTDCEDTTNHNILQARNRIEEFFRSQAYIFNHDLNKTLPAMHFVDHSFQIWFVVLGLLVLMLMLHVRPAFPSKSTELNHASKFQHED", "length": 308, "header": "tr|F6QJG7-1|F6QJG7_BOVIN Isoform 1 of Zona pellucida binding protein 2 OS=Bos taurus OX=9913 GN=ZPBP2 PE=4 SV=2 CANONICAL=F6QJG7-1" }, "locus": { "chromosome": "19", "start_pos": 40226101, "end_pos": 40217609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043078.4", "url": "https://www.ensembl.org/id/ENSBTAT00000043078.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040673.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040673.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q6PVW7-1", "protein_name": "Zona pellucida-binding protein 2", "gene_name": "ZPBP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGGGGRPCSPQRALLGMVAIMAVVAEARWGAPGRARAAPEEDQISVGFFRKNVIYGNVRRAENVYVKMFTNSPSLVCMDLSLSQEEIIDPKYSWTGPDGRNLEGRGYANLTGSGELMLVGFQESMSGAYTCTLSHRIIETSAQEEVDVRDTYRFMVYAYREANHVYQVSVRFTAKGCELAANARFVEELKKIMESLISDLTCGVKGPSYRCHSLEAPHRGSPSELFITFQVNPFAPGWEDLCSRLPQDCEDTTNRRAQEATERIGEFFRKQTYALKHQFQTVPTIHYVEGSFSVTPIDSCRPGFGRNNITHRSCAGCCVVCSPGTYSPDSAGSCRVCAGRRTAGYGAKSCP", "length": 352 }, "evidence": [ { "id": "F6QJG7", "url": "https://omabrowser.org/oma/group/F6QJG7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6X782-1", "protein_name": "Zona pellucida-binding protein 2", "gene_name": "Zpbp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAWALLSAVLWSLAGVGSARSSLFSNEGFVYGTVGHPVKIYVKLHQTSPVLVCMDIDRASKETVDPIYLWIGPNENTLTGSSQINITNIGELVLKDFMESLSGHYSCTLSYKIVKAETQEETSLKKKYDFLVFAYREPDYSYRMAVRFTTKSCVGRYNDLLFRLLKKILDNLISDLLCHVIEPSYKCHSVKIPERDFVYELFVAFQVNPFAPGWKSMCNSSMDCEDVTNHNILKARDRIEEFFRSQAYILHHHFNITVPAMHFVDHSFQVTRIDNCRPGFGKNEGLHSNCASCCVVCSPGTFSPDMDVTCQTCVSAHVYGAKACP", "length": 326 }, "evidence": [ { "id": "F6QJG7", "url": "https://omabrowser.org/oma/group/F6QJG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6X784-1", "protein_name": "Zona pellucida-binding protein 2", "gene_name": "ZPBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMRTCVLLSAVLWCLTGVQCPRFTLFNKKGFIYGKTGQPDKIYVELHQNSPVLICMDFKLSKKEIVDPTYLWIGPNEKTLTGNNRINITETGQLMVKDFLEPLSGLYTCTLSYKTVKAETQEEKTVKKRYDFMVFAYREPDYSYQMAVRFTTRSCIGRYNDVFFRVLKKILDSLISDLSCHVIEPSYKCHSVEIPEHGLIHELFIAFQVNPFAPGWKGACNGSVDCEDTTNHNILQARDRIEDFFRSQAYIFYHNFNKTLPAMHFVDHSLQVVRLDSCRPGFGKNERLHSNCASCCVVCSPATFSPDVNVTCQTCVSVLTYGAKSCPQTSNKNQQYED", "length": 338 }, "evidence": [ { "id": "F6QJG7", "url": "https://omabrowser.org/oma/group/F6QJG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6X786-1", "protein_name": "Zona pellucida-binding protein 2", "gene_name": "Zpbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAWALLYAVLWSLAGVGSQRSSLFNIKGFVYGTVGHPVKIYVKLHQASPVLICMDIDRANKETVDPTYLWTGPNENTLKGNSQINITNTGELVLKDFLEPLSGLYSCMLSYKTIKAETQEETMIKKKYDFLVFAYREPDYSYHMAVRFTTGSCVGRHNDLLFRVLKKILDNLISDLLCHVIEPSYKCHFVKLPERDFLYELFIAFQVNPFAPGWRSLCNRSADCEDITNHNVLKARDRMEEFFRKQAHILHHHFNRTVPAMHFVDHSFQVTRIDNCRPGFGKNEGLHSNCATCCVVCSPGTFSPDVDVTCQICVSVHIYGAKACP", "length": 326 }, "evidence": [ { "id": "F6QJG7", "url": "https://omabrowser.org/oma/group/F6QJG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6QJG7", "url": "https://www.uniprot.org/uniprotkb/F6QJG7" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "F6QJG7", "url": "https://www.uniprot.org/uniprotkb/F6QJG7" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "F6QJG7", "url": "https://www.uniprot.org/uniprotkb/F6QJG7" } ], "pmid": "" }, { "name": "zona pellucida receptor complex", "id": "GO:0002199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002199", "evidence": [ { "database": "UniProtKB", "id": "F6QJG7", "url": "https://www.uniprot.org/uniprotkb/F6QJG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "binding of sperm to zona pellucida", "id": "GO:0007339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007339", "evidence": [ { "database": "UniProtKB", "id": "F6QJG7", "url": "https://www.uniprot.org/uniprotkb/F6QJG7" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", 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May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. 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"crossref": [ { "id": "F6QN89", "url": "https://alphafold.ebi.ac.uk/entry/F6QN89", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001654", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001654", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01258", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01258", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DGGRQHW", "url": "https://omabrowser.org/oma/group/DGGRQHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QN89", "url": "https://www.orthodb.org/?gene=F6QN89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10554", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10554", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10554:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10554:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QN89-1", "url": "https://www.uniprot.org/uniprotkb/F6QN89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNESPLGAGPGPPPRAGRGKRRGCLTGMRVAAATEAAGAGPTMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAESEPALGPAAAAFNGLPNGGGAGDSLPGSPSRGLGPPSPPAPPRSPAGEAGASPPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLVSDLPWEGAAPQSPSFSGSEDSGSPKHQNSTKDRKVIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSKEVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSTWTRILVQGCHAAAELIKEVSLGCTLNGQEVKLTIHYESGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV", "length": 568, "header": "tr|F6QN89-1|F6QN89_BOVIN Isoform 1 of Beta-2-syntrophin OS=Bos taurus OX=9913 GN=SNTB2 PE=3 SV=1 CANONICAL=F6QN89-1" }, "isoforms": [ { "isoform_ac": "F6QN89-1", "url": "https://www.uniprot.org/uniprotkb/F6QN89/entry", "sequence": { "sequence": "MNNESPLGAGPGPPPRAGRGKRRGCLTGMRVAAATEAAGAGPTMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAESEPALGPAAAAFNGLPNGGGAGDSLPGSPSRGLGPPSPPAPPRSPAGEAGASPPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLVSDLPWEGAAPQSPSFSGSEDSGSPKHQNSTKDRKVIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSKEVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSTWTRILVQGCHAAAELIKEVSLGCTLNGQEVKLTIHYESGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV", "length": 568, "header": "tr|F6QN89-1|F6QN89_BOVIN Isoform 1 of Beta-2-syntrophin OS=Bos taurus OX=9913 GN=SNTB2 PE=3 SV=1 CANONICAL=F6QN89-1" }, "locus": { "chromosome": "18", "start_pos": 36448362, "end_pos": 36384396, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002168.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002168.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002168.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002168.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZMX6-1", "protein_name": "Beta-2-syntrophin", "gene_name": "Sntb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNESPGGGEGSAPPRAGRGKRRGCLTGIGGAAATAAAGAGLAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAVEPEPPAVAFNGLPNGGGGGGDSLPGSPNRGLGPPSPPAPPRGPAGEASASPPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLVSDLPWEGASPQSPSFSGSEDSGSPKHQNTTKDRKVIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSKEVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSTWTRILVQGCHAAAELIKEVSLGCTLSGQDVRFTVHYEHGFTITRDNGGTSSILYRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV", "length": 565 }, "evidence": [ { "id": "F6QN89", "url": "https://omabrowser.org/oma/group/F6QN89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FDL7-1", "protein_name": "Beta-2-syntrophin", "gene_name": "sntb2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAVWTRAEKQGHLDLLLSDRWVRVSAELTRDNLTLTAEGEPGGPAGYPEHNSHLKNGVSNGNEQNRDVFTNRVQYDNSPGRVNGTGSDSESSGYCDSEGVRRVRIVKQESGGLGISIKGGRENRMPILISKIFPGLAADQSRALRVGDAILSVNGSDLRDATHDAAVQALKKAGKEVTLEVKYIREVSPLFKKSSMSADLSWDGRLQSPNLSSSDESPKSSVSRDRKVIPLKMSFISRNLTMPDPENRLLELHSPDGQHTVVLRCKDGATAHSWFTAIHTNVAALLPQTLSYINTFLNNANTHCTLKHIGWLVEQLDMDGSRHQYKRVIMALTEKDILLFQAVPWTYESWTTPVLTHPLLATRLVHSGSVRSSPALGGDLLFATRTGTGRGIESHVFRVETHWDLSTWTRALVQGGHSAAELIKEVSIGCVLNRQNVRLILHYERGFTVTRESGDSVLFHFPYERLKMSADDGVRNLFLDFGAPEGEMVFELHSGPKPVVFVLHSFLSAKLARLGLLT", "length": 519 }, "evidence": [ { "id": "F6QN89", "url": "https://omabrowser.org/oma/group/F6QN89/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q13425-1", "protein_name": "Beta-2-syntrophin", "gene_name": "SNTB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVAAATAAAGAGPAMAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAAELEPALGPAAAAFNGLPNGGGAGDSLPGSPSRGLGPPSPPAPPRGPAGEAGASPPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLVSDLPWEGAAPQSPSFSGSEDSGSPKHQNSTKDRKIIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSKEVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSSWTRILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV", "length": 540 }, "evidence": [ { "id": "F6QN89", "url": "https://omabrowser.org/oma/group/F6QN89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61235-1", "protein_name": "Beta-2-syntrophin", "gene_name": "Sntb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVWTRATKAGLVELLLRERWVRVVAELSGESLSLTGDAAAVEPEPPAAAFNGLPNGGGGESLPGSPNRGLGPPSPPAPPRGPAGEASASPPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLVSDLPWEGASPQSPSFSGSEDSGSPKHQNTTKDRKVIPLKMCFAARNLSMPDLENRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSKEVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEMHLFRVETHRDLSTWTRILVQGCHAAAELIKEVSLGCTLSGQEVRFTVHYEHGFTITRDNGGASSILYRYPFERLKMSADDGIRNLYLDFGGPEGELTMDLHSCPKPIVFVLHTFLSAKVTRMGLLV", "length": 520 }, "evidence": [ { "id": "F6QN89", "url": "https://omabrowser.org/oma/group/F6QN89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "dystrophin-associated glycoprotein complex", "id": "GO:0016010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016010", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "F6QN89", "url": "https://www.uniprot.org/uniprotkb/F6QN89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QN89-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 568, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QN89-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QN89" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QN89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QN89" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 226, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QN89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QN89" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 353, "end_pos": 465, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 43 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QND5-1", "uniprot_ac": "F6QND5", "uniprot_id": "F6QND5_BOVIN", "mass": { "chemical_mass": 94734.0, "monoisotopic_mass": 94734.0 }, "refseq": {}, "gene_names": [ { "name": "FGA", "type": "recommended", "evidence": [ { "id": "F6QND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ] } ], "protein_names": [ { "name": "Fibrinogen alpha chain", "type": "recommended", "evidence": [ { "id": "F6QND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QND5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVV7#function" }, { "database": "UniProtKB", "id": "ARBA00054782", "url": "https://www.uniprot.org/uniprotkb/ARBA00054782#function" }, { "database": "UniProtKB", "id": "A0ABI0P6Q0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q0#function" }, { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FGA", "url": "https://www.uniprot.org/uniprotkb/F6QND5", "locus": { "chromosome": "17", "start_pos": 2869673, "end_pos": 2860538, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001638", "url": "https://www.ensembl.org/id/ENSBTAG00000001638" } ] } } ], "crossref": [ { "id": "F6QND5", "url": "https://alphafold.ebi.ac.uk/entry/F6QND5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001638", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001638", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PRIVEHM", "url": "https://omabrowser.org/oma/group/PRIVEHM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVV7", "url": "https://www.orthodb.org/?gene=A0A3Q1LVV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QND5", "url": "https://www.orthodb.org/?gene=F6QND5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5686938", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9769733", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPT0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPT0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6Q0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QND5-1", "url": "https://www.uniprot.org/uniprotkb/F6QND5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTGRGGSLPFFQLGAPLESALSTAEMFSVRDLCLVLSLVGAIKTEDGSDPPSGDFLTEGGGVRGPRLVERQQSACKETGWPFCSDEDWNTKCPSGCRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTFKQISEDLRSRIEILRRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDIQYLPLIKMSTITGPVPREFKSQLQEAPLEWKALLEMQQTKMVLETFGGDGHARGDSVSQGTGLAPGSPRKPGTSSIGNVNPGSYGPGSSGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKQEFHTGKLVTTKGDKELLIDNEKVTSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADFDWHHTFPSRGNLDDFFHRDKDDFFTRSSHEFDGRTGLAPEFAALGESGSSSSKTSTHSKQFVSSSTTVNRGGSAIESKHFKMEDEAESLEDLGFKGAHGTQKGHTKARPARDCYDVLQTRPSGAQSGIFSIKLPASSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGSILRVELEDWAGKGAYAEYHLRVGSEAEDYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ", "length": 863, "header": "tr|F6QND5-1|F6QND5_BOVIN Isoform 1 of Fibrinogen alpha chain OS=Bos taurus OX=9913 GN=FGA PE=4 SV=1 CANONICAL=F6QND5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVV7/entry", "sequence": { "sequence": "MFSVRDLCLVLSLVGAIKTEDGSDPPSGDFLTEGGGVRGPRLVERQQSACKETGWPFCSDEDWNTKCPSGCRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTFKQISEDLRSRIEILRRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDIQYLPLIKMSTITGPVPREFKSQLQEAPLEWKALLEMQQTKMVLETFGGDGHARGDSVSQGTGLAPGSPRKPGTSSIGNVNPGSYGPGSSGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKQEFHTGKLVTTKGDKELLIDNEKVTSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADFDWHHTFPSRGNLDDFFHRDKDDFFTRSSHEFDGRTGLAPEFAALGESGSSSSKTSTHSKQFVSSSTTVNRGGSAIESKHFKMEDEAESLEDLGFKGAHGTQKGHTKARPARGIHTSPLGEPSLTP", "length": 602, "header": "tr|A0A3Q1LVV7-1|A0A3Q1LVV7_BOVIN Computationally mapped isoform of Fibrinogen alpha chain OS=Bos taurus OX=9913 GN=FGA PE=4 SV=3 CANONICAL=F6QND5-1" }, "locus": { "chromosome": "17", "start_pos": 2867263, "end_pos": 2860815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070854.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070854.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061562.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061562.3" } ] } }, { "isoform_ac": "A0ABI0NPT0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPT0/entry", "sequence": { "sequence": "MFSVRDLCLVLSLVGAIKNTKCPSGCRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTFKQISEDLRSRIEILRRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDIQYLPLIKMSTITGPVPREFKSQLQEAPLEWKALLEMQQTKMVLETFGGDGHARGDSVSQGTGLAPGSPRKPGTSSIGNVNPGSYGPGSSGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKQEFHTGKLVTTKGDKELLIDNEKVTSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADFDWHHTFPSRGNLDDFFHRDKDDFFTRSSHEFDGRTGLAPEFAALGESGSSSSKTSTHSKQFVSSSTTVNRGGSAIESKHFKMEDEAESLEDLGFKGAHGTQKGHTKARPARGIHTSPLGEPSLTP", "length": 570, "header": "tr|A0ABI0NPT0-1|A0ABI0NPT0_BOVIN Computationally mapped isoform of Fibrinogen alpha chain OS=Bos taurus OX=9913 GN=FGA PE=4 SV=1 CANONICAL=F6QND5-1" }, "locus": { "chromosome": "17", "start_pos": 2867263, "end_pos": 2860815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152894.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152894.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104078.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104078.1" } ] } }, { "isoform_ac": "A0ABI0P6Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q0/entry", "sequence": { "sequence": "HMCVLSICLFKFWTHKTEDGSDPPSGDFLTEGGGVRGPRLVERQQSACKETGWPFCSDEDWNTKCPSGCRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTFKQISEDLRSRIEILRRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDIQYLPLIKMSTITGPVPREFKSQLQEAPLEWKALLEMQQTKMVLETFGGDGHARGDSVSQGTGLAPGSPRKPGTSSIGNVNPGSYGPGSSGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKQEFHTGKLVTTKGDKELLIDNEKVTSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADFDWHHTFPSRGNLDDFFHRDKDDFFTRSSHEFDGRTGLAPEFAALGESGSSSSKTSTHSKQFVSSSTTVNRGGSAIESKHFKMEDEAESLEDLGFKGAHGTQKGHTKARPARGIHTSPLGEPSLTP", "length": 613, "header": "tr|A0ABI0P6Q0-1|A0ABI0P6Q0_BOVIN Computationally mapped isoform of Fibrinogen alpha chain OS=Bos taurus OX=9913 GN=FGA PE=4 SV=1 CANONICAL=F6QND5-1" }, "locus": { "chromosome": "17", "start_pos": 2867263, "end_pos": 2862574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145166.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145166.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107083.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107083.1" } ] } }, { "isoform_ac": "F6QND5-1", "url": "https://www.uniprot.org/uniprotkb/F6QND5/entry", "sequence": { "sequence": "MGTGRGGSLPFFQLGAPLESALSTAEMFSVRDLCLVLSLVGAIKTEDGSDPPSGDFLTEGGGVRGPRLVERQQSACKETGWPFCSDEDWNTKCPSGCRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTFKQISEDLRSRIEILRRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDIQYLPLIKMSTITGPVPREFKSQLQEAPLEWKALLEMQQTKMVLETFGGDGHARGDSVSQGTGLAPGSPRKPGTSSIGNVNPGSYGPGSSGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKQEFHTGKLVTTKGDKELLIDNEKVTSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADFDWHHTFPSRGNLDDFFHRDKDDFFTRSSHEFDGRTGLAPEFAALGESGSSSSKTSTHSKQFVSSSTTVNRGGSAIESKHFKMEDEAESLEDLGFKGAHGTQKGHTKARPARDCYDVLQTRPSGAQSGIFSIKLPASSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGSILRVELEDWAGKGAYAEYHLRVGSEAEDYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ", "length": 863, "header": "tr|F6QND5-1|F6QND5_BOVIN Isoform 1 of Fibrinogen alpha chain OS=Bos taurus OX=9913 GN=FGA PE=4 SV=1 CANONICAL=F6QND5-1" }, "locus": { "chromosome": "17", "start_pos": 2868669, "end_pos": 2860737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002145.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002145.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002145.4", "url": "https://www.ensembl.org/id/ENSBTAP00000002145.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-5686938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "resource": "Reactome", "description": "Regulation of TLR by endogenous ligand" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-BTA-9769733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769733", "resource": "Reactome", "description": "Fibrin formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LLL7-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "Fga", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSLKVTCLILSVASTVWASDTGGEFIEEGATGRGPRVVEKQQSQCRETDWPFCSDEDWNHKCPSGCRMQGLIDEVNRDFINRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANNFDNTYGQVSEELRRRIEVLKRKVVEKAQQIQVLQNNVRTQLIDMKRLEVDIDIKIRSCKGSCSRGVAREIDLRDYEGQQKQLEQVIAKDLLPSKDRQYLPAIKMSPVPDLIPGSFKSQLQEAPPEWKALTEMRQMRMELEGHVKGGDSRGHPRGDSPTHRPGAEAENPTNSGPGGSGYWRPGSSRPESDGNLNAEDREFEGSSRPSSYRPSSSGSGSAMPSNPDWGEFSEFTGSSSPAIKKEYHTGKVTTSKGDKELMIGNEKVTSTSTSTTRRSCSKTITKTVTGPDGRREVVKEVVTSDDGSDCGGSVDLGMTHGFGGRFDEFAQRFPDQAAFFDSHFDSLSSNFKELGSKTHAVGSDSGIFTDLEDPRTHVPDYSSSSKTSTVRKQVTKSYKMADEAGSEAHHEGETKTTKRARAKSRPSRDCDDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRASVLRVELEDWAGKQAYAEYHFQVGSEAEGYALQVSSYQGTAGNALMEGSEEEGAEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWIPFRGADYSLKAVRMKIRPLVEQ", "length": 781 }, "evidence": [ { "id": "F6QND5", "url": "https://omabrowser.org/oma/group/F6QND5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B8A5L6-1", "protein_name": "Fibrinogen alpha chain precursor", "gene_name": "fga", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFTHSLLCLFVAVSSALAEEDTVVNPRGARPIEHGFKAQDTCQTKEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSGYDNRYMSLAEQLRQRITDIKIKIDRQLRLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCASYSEFSVDRESYVTLDKQMDNLNAMRVQSVETVSSLGIMKSRPLKDVLVPTIYKSGTGKAEQKLLFGDVGQMQLSLEAEGSTAESAATVSKFPTSGTGSTSQTSSKQCTKSVRKVITHTKDGPVEKVEVSSSGPGCDDLGKLGISDSEFLTAAKDGKDLSRDGLKITVTGGDEKSLTSLSHSTSDLGGFGGDFFKNLGTDNRKYASSSSSTSTKTVSDGSKSYSKTTLTSDPIFGDDLGAFMRGDVEEDMPDIHARSVKSQDDRKAGFVGGDCVEIQQKHVNGGQSGMFKIKPAGSEEVVEVYCDQSTGLGGWTLVQQREDGSVNFNRTWKEYLNGFGQIDKQGKGEIWIGNKFLHLLTQKESLLRVELQDWTGAEAYAEYNIKVGSEAEGFPLTASDYDGDAGDALVRGHPNLGSFLSHAGMKFSTFDRDSDKWEENCAEMYGGGWWYNNCQSANLNGIYYKGGQYDPATKVPYEIENGVVWLPFKPADYSLKVVRMKIRPV", "length": 684 }, "evidence": [ { "id": "F6QND5", "url": "https://omabrowser.org/oma/group/F6QND5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PV24-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "Fga", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLRVTCLILSVASTVWTTDTEDKGEFLSEGGGVRGPRVVERHQSQCKDSDWPFCSDDDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGDFANANNFDNTYGQVSEDLRRRIEILRRKVIEKAQQIQALQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRAVNREINLQDYEGHQKQLQQVIAKELLPTKDRQYLPALKMSPVPDLVPGSFKSQLQEAPPEWKALTEMRQMRMELERPGKDGGSRGDSPGDSRGDSRGDFATRGPGSKAENPTNPGPGGSGYWRPGNSGSGSDGNRNPGTTGSDGTGDWGTGSPRPGSDSGNFRPANPNWGVFSEFGDSSSPATRKEYHTGKAVTSKGDKELLIGKEKVTSSGTSTTHRSCSKTITKTVTGPDGRREVVKEVITSDDGSDCGDATELDISHSFSGSLDELSERHPDLSGFFDNHFGLISPNFKEFGSKTHSDSDILTNIEDPSSHVPEFSSSSKTSTVKKQVTKTYKMADEAGSEAHREGETRNTKRGRARARPTRDCDDVLQTQTSGAQNGIFSIKPPGSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYRGTAGDALVQGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVGQ", "length": 789 }, "evidence": [ { "id": "F6QND5", "url": "https://omabrowser.org/oma/group/F6QND5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P02671-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "FGA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ", "length": 866 }, "evidence": [ { "id": "F6QND5", "url": "https://omabrowser.org/oma/group/F6QND5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P06399-1", "protein_name": "Fibrinogen alpha chain", "gene_name": "Fga", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "fibrinolysis", "id": "GO:0042730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042730", "evidence": [ { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "pmid": "" }, { "name": "platelet aggregation", "id": "GO:0070527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527", "evidence": [ { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "pmid": "" }, { "name": "protein polymerization", "id": "GO:0051258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051258", "evidence": [ { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "pmid": "" }, { "name": "blood coagulation, common pathway", "id": "GO:0072377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072377", "evidence": [ { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "pmid": "" }, { "name": "positive regulation of heterotypic cell-cell adhesion", "id": "GO:0034116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034116", "evidence": [ { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "pmid": "" }, { "name": "platelet activation", "id": "GO:0030168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030168", "evidence": [ { "database": "UniProtKB", "id": "F6QND5", "url": "https://www.uniprot.org/uniprotkb/F6QND5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QND5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 863, "overlap": "1.0", "method": 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} ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QP63-1", "uniprot_ac": "F6QP63", "uniprot_id": "F6QP63_BOVIN", "mass": { "chemical_mass": 24834.0, "monoisotopic_mass": 24834.0 }, "refseq": { "ac": "XP_059742249", "name": "BH3-interacting domain death agonist isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742249" }, "gene_names": [ { "name": "BID", "type": "recommended", "evidence": [ { "id": "F6QP63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QP63" } ] }, { "name": "BID", "type": "synonym", "evidence": [ { "id": "XP_059742249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742249" } ] } ], "protein_names": [ { "name": "BH3-interacting domain death agonist", "type": "recommended", "evidence": [ { "id": "F6QP63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QP63/entry#names_and_taxonomy" } ] }, { "name": "BH3-interacting domain death agonist isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059742249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742249" } ] } ], "function": [ { "annotation": "Induces caspase activation and apoptosis. Translocates to mitochondria following cleavage and disrupts the outer mitochondrial membrane leading to the release of cytochrome c.", "evidence": [ { "database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63#function" }, { "database": "UniProtKB", "id": "ARBA00094526", "url": "https://www.uniprot.org/uniprotkb/ARBA00094526#function" } ] }, { "annotation": "Induces caspases and apoptosis. Counters the protective effect of BCL2.", "evidence": [ { "database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63#function" }, { "database": "UniProtKB", "id": "PIRNR038018", "url": "https://www.uniprot.org/uniprotkb/PIRNR038018#function" }, { "database": "UniProtKB", "id": "ARBA00057135", "url": "https://www.uniprot.org/uniprotkb/ARBA00057135#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BID", "url": "https://www.uniprot.org/uniprotkb/F6QP63", "locus": { "chromosome": "5", "start_pos": 109136161, "end_pos": 109154338, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013988", "url": "https://www.ensembl.org/id/ENSBTAG00000013988" } ] } } ], "crossref": [ { "id": "F6QP63", "url": "https://alphafold.ebi.ac.uk/entry/F6QP63", "database": "AlphaFoldDB", "categories": [] }, { "id": "510373", "url": "https://www.ncbi.nlm.nih.gov/gene/510373", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR35447", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35447", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35447:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35447:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059742249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742249", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QP63-1", "url": "https://www.uniprot.org/uniprotkb/F6QP63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSRRLRAPPPGRGLFPRAPGALRRAAVPPPRSAVEVSNGPGPGDERTTSLLLLGFLQSCPHSCFQRELEALGHELPGHLFHDDELQTDGNRCSHFPLAAEAETDSERQEEAVREVARQLAQIGDRLEGSIHPGMVAGLASRFSVRSLSEEDRRQCLAAALEQLMQTCPPDVDHEKTQLLLTMLLAKKIADHSPALLRDVFHTTVTFINQNLLAYVRNLVRNQMD", "length": 225, "header": "tr|F6QP63-1|F6QP63_BOVIN Isoform 1 of BH3-interacting domain death agonist OS=Bos taurus OX=9913 GN=BID PE=4 SV=1 CANONICAL=F6QP63-1" }, "isoforms": [ { "isoform_ac": "F6QP63-1", "url": "https://www.uniprot.org/uniprotkb/F6QP63/entry", "sequence": { "sequence": "MGSRRLRAPPPGRGLFPRAPGALRRAAVPPPRSAVEVSNGPGPGDERTTSLLLLGFLQSCPHSCFQRELEALGHELPGHLFHDDELQTDGNRCSHFPLAAEAETDSERQEEAVREVARQLAQIGDRLEGSIHPGMVAGLASRFSVRSLSEEDRRQCLAAALEQLMQTCPPDVDHEKTQLLLTMLLAKKIADHSPALLRDVFHTTVTFINQNLLAYVRNLVRNQMD", "length": 225, "header": "tr|F6QP63-1|F6QP63_BOVIN Isoform 1 of BH3-interacting domain death agonist OS=Bos taurus OX=9913 GN=BID PE=4 SV=1 CANONICAL=F6QP63-1" }, "locus": { "chromosome": "5", "start_pos": 109154333, "end_pos": 109137165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042737.5", "url": "https://www.ensembl.org/id/ENSBTAT00000042737.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040367.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040367.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { 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"database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63" } ], "pmid": "" }, { "name": "release of cytochrome c from mitochondria", "id": "GO:0001836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001836", "evidence": [ { "database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63" } ], "pmid": "" }, { "name": "positive regulation of release of cytochrome c from mitochondria", "id": "GO:0090200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090200", "evidence": [ { "database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63" } ], "pmid": "" }, { "name": "positive regulation of intrinsic apoptotic signaling pathway", "id": "GO:2001244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001244", "evidence": [ { "database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63" } ], "pmid": "" }, { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "F6QP63", "url": "https://www.uniprot.org/uniprotkb/F6QP63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QPI1-1", "uniprot_ac": "F6QPI1", "uniprot_id": "F6QPI1_BOVIN", "mass": { "chemical_mass": 64430.0, "monoisotopic_mass": 64430.0 }, "refseq": { "ac": "NP_001192787", "name": "protein NDNF precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192787" }, "gene_names": [ { "name": "NDNF", "type": "recommended", "evidence": [ { "id": "F6QPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ] }, { "name": "C6H4orf31", "type": "synonym", "evidence": [ { "id": "NP_001192787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192787" } ] }, { "name": "NDNF", "type": "synonym", "evidence": [ { "id": "NP_001192787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192787" } ] } ], "protein_names": [ { "name": "Protein NDNF", "type": "recommended", "evidence": [ { "id": "F6QPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QPI1/entry#names_and_taxonomy" } ] }, { "name": "fibronectin type-III domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001192787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192787" } ] }, { "name": "protein NDNF precursor", "type": "synonym", "evidence": [ { "id": "NP_001192787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192787" } ] } ], "function": [ { "annotation": "Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms.", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1#function" }, { "database": "UniProtKB", "id": "ARBA00046135", "url": "https://www.uniprot.org/uniprotkb/ARBA00046135#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NDNF", "url": "https://www.uniprot.org/uniprotkb/F6QPI1", "locus": { "chromosome": "6", "start_pos": 4414617, "end_pos": 4403233, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010634", "url": "https://www.ensembl.org/id/ENSBTAG00000010634" } ] } } ], "crossref": [ { "id": "F6QPI1", "url": "https://alphafold.ebi.ac.uk/entry/F6QPI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010634", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010634", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "519500", "url": "https://www.ncbi.nlm.nih.gov/gene/519500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519500", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLFRDTS", "url": "https://omabrowser.org/oma/group/YLFRDTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QPI1", "url": "https://www.orthodb.org/?gene=F6QPI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14619:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14619:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192787", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QPI1-1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPLHWCMLWLLLPLSSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLSVTVTPCDAPLEWKLSLQELPEEASGEGSGDPEPLDQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASVLKQPIQYCVVVSREHNFKSLCAVEAKLSADDAFMMAPKPGLDFSPFDFAHFGFASENSAKERSFLTKPSPKLGRHAHSRPKADIQKVCIGNKNIFTVSDLKPDTQYYFDVFVANSDSNMSTAYLGTFARTKEEAKQKTVELKDGKVTDVFVKRKGAKFLRFAPVPSHQKVTFFVHSCLDAVQIQVRRDGKLLLSQNVEGIRQFQLRGKPKAKYLIRLKGNKKGASMLKILATTRPSKQSFPSLPEDRRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIKGLQPGKSYLLDVYVTGHGGHSVKYQSKVVKTRKVC", "length": 568, "header": "tr|F6QPI1-1|F6QPI1_BOVIN Isoform 1 of Protein NDNF OS=Bos taurus OX=9913 GN=NDNF PE=4 SV=2 CANONICAL=F6QPI1-1" }, "isoforms": [ { "isoform_ac": "F6QPI1-1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1/entry", "sequence": { "sequence": "MVPLHWCMLWLLLPLSSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLSVTVTPCDAPLEWKLSLQELPEEASGEGSGDPEPLDQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASVLKQPIQYCVVVSREHNFKSLCAVEAKLSADDAFMMAPKPGLDFSPFDFAHFGFASENSAKERSFLTKPSPKLGRHAHSRPKADIQKVCIGNKNIFTVSDLKPDTQYYFDVFVANSDSNMSTAYLGTFARTKEEAKQKTVELKDGKVTDVFVKRKGAKFLRFAPVPSHQKVTFFVHSCLDAVQIQVRRDGKLLLSQNVEGIRQFQLRGKPKAKYLIRLKGNKKGASMLKILATTRPSKQSFPSLPEDRRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIKGLQPGKSYLLDVYVTGHGGHSVKYQSKVVKTRKVC", "length": 568, "header": "tr|F6QPI1-1|F6QPI1_BOVIN Isoform 1 of Protein NDNF OS=Bos taurus OX=9913 GN=NDNF PE=4 SV=2 CANONICAL=F6QPI1-1" }, "locus": { "chromosome": "6", "start_pos": 4413943, "end_pos": 4403331, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014058.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014058.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014058.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014058.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:519500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519500", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480Y2S8-1", "protein_name": "Protein NDNF", "gene_name": "NDNF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVPLHWCMLWLLLPLSSKTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEINSYLFRDTPKRYFFVVEEDNTPLSVTVTPCDAPLEWKLSLQELPEEASGEGSGDLEPLDQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASLLKQPIQYCVVINKEHNFKSLCAVEAKLSADDAFMMAPKPGVDFSPFDFAHFGFPSDNSGKERSFLTKPSPKLGRHAYSRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFVANSNSNTSTAYVGTFARTKEEAKQKTVELKDGKVTDVFVKRKGAKFLRFAPVSSHQKVTFFIHSCLDAVQIQVRRDGKLLLSQNVEGIRQFQLRGKPKAKYLIRLKGNKKGASLLKILATTRPSKQSFPSLPEDTRIKAFDKLRTCSSATVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIKGLQPGKSYLLDVYVIGHGGHSVKYQSKVVKTRKFC", "length": 568 }, "evidence": [ { "id": "F6QPI1", "url": "https://omabrowser.org/oma/group/F6QPI1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LE57-1", "protein_name": "Protein NDNF", "gene_name": "Ndnf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMELLYWCLLCLLLPLTSRTQKLPTRDEELFQMQIRDKALFHDSSVIPDGAEISSYLFRDTPRRYFFMVEEDNTPLSVTVTPCDAPLEWKLSLQELPEESSADGSGDPEPLDQQKQQMTDVEGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPDLPYDPRVDVTSIGRTTVTLAWKQSPTASMLKQPIEYCVVINKEHNFKSLCAAETKMSADDAFMVAPKPGLDFSPFDFAHFGFPTDNLGKDRSFLAKPSPKVGRHVYWRPKVDIKKICIGSKNIFTVSDLKPNTQYYFDVFMVNTNTNMSTAFVGAFARTKEEAKQKTVELKDGRVTDVVVKRKGKKFLRFAPVSSHQKVTLFIHSCMDTVQVQVRRDGKLLLSQNVEGIRQFQLRGKPKGKYLIRLKGNKKGASMLKILATTRPSKHAFPSLPDDTRIKAFDKLRTCSSVTVAWLGTQERRKFCIYRKEVGGNYSEEQKRRERNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIRDLQPGKSYLLDVYVVGHGGHSVKYQSKLVKTRKVC", "length": 569 }, "evidence": [ { "id": "F6QPI1", "url": "https://omabrowser.org/oma/group/F6QPI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NIF2-1", "protein_name": "Protein NDNF", "gene_name": "NDNF", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLLHCPLLLLLLPLSSRMQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLAVTVTPCDAPLEWKLSVQELPEEASGEGSGEPEPLEQQKQQITNEEGTELFSYKGNDVEYFVSSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRIDVTSLGRTTVTLAWKPSPTASLLKQPIQYCIVINKEHNFKSLCAVEAKLSSDDAFMMAPKPGLDFSPFDFAHFGFPSDSNAGKERGFLKSPSKFGRQTSSKPRVDLHKVCIGNKNIFTVSDLKPDTQYYFDMFAVNTNTNLSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGAKFLRFAPVSSHQKVTFSVHSCLDAVQIQVRRDGKLLLSQNVEGVRQFQLRGKAKAKYLIRLKGNKKGASMLKILATTRPNKQLFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEEQKKREQNQCLGPDTRKKSEKVLCKYFHSQNIQKAVTTETIRGLQSGKSYLLDVYVIGHGGHSVKYQSKLVKTRKFC", "length": 568 }, "evidence": [ { "id": "F6QPI1", "url": "https://omabrowser.org/oma/group/F6QPI1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HT67-1", "protein_name": "Protein NDNF", "gene_name": "Ndnf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLLHWCLLWLLLPLTSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEMSSYLFKDTPRRYFFMVEEDNTPLSVTVTPCDAPLEWKLSLQELPEEGSADGSGDPEPLDQQKQQVTDVKGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLVWKPSPTASMLKQPIEYCVVINKEHNFKSLCAVETKMSADDTFMMAPKPGLDFSPFDFAHFGFPIDNLGKDRSFLAKPPKVGRHAYWRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFMVNTNSNLSTAYVGTFAKTKEEAKQKIMELKDGRVTDVFVKRRGTKFLRFAPVSTHQKASFFIYSCLDAVQVQVKRDGKLLLSQNVEGIRHFQLRGKPKAKYLIRLRGNRKATSMLKILATTKPNKQAFPSLPEDTRIKAFDKLRTCSSVTVAWVGTQERRKFCIYRKEVDGNYSEDQKRREQNRCLGPDTRKKSEKVLCKYFHSPNRKKAVTTETIKDLQPGKSYLLDVYVVGHGGHSVKYQSKVVKTRKVC", "length": 567 }, "evidence": [ { "id": "F6QPI1", "url": "https://omabrowser.org/oma/group/F6QPI1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8C119-1", "protein_name": "Protein NDNF", "gene_name": "Ndnf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELFYWCLLCLLLPLTSRTQKLPTRDEELFQMQIRDKEFFHDSSVIPDGAEVSSYLFRDTPRRYFFMVEEDNTPLSVTVTPCDAPLEWKLSLQELHEGSSADGSGDPELLDQQKQQMTDVEGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSFGRTTVTLAWKPSPTASILKQPIEYCVVINKEHNFKSLCAAETKMNADDAFMVAPKPGLDFNPFDFAHFGFPTDNLGKDRSLLAKPSPKVGRHVYWRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFMVNTNTNMSTAYVGAFVRTKEEAKQKTVELKDGRVTDVFVKRKGKKFLRFAPVSSHQKVTFFIHSCMDAVQVQVRRDGRLLLSQNVEGIRQFQLRGKPKGKYLIRLKGNRKGASKLKILATTRPSKHAFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERRKFCIYRKEVDGNYSEDQKRREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIRDLQPGKSYLLDVYVVGHGGHSVKYQSKIVKTRKVC", "length": 568 }, "evidence": [ { "id": "F6QPI1", "url": "https://omabrowser.org/oma/group/F6QPI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB73-1", "protein_name": "Protein NDNF", "gene_name": "NDNF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLLHWCLLWLLFPLSSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLSVTVTPCDAPLEWKLSLQELPEDRSGEGSGDLEPLEQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASLLKQPIQYCVVINKEHNFKSLCAVEAKLSADDAFMMAPKPGLDFSPFDFAHFGFPSDNSGKERSFQAKPSPKLGRHVYSRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFVVNINSNMSTAYVGTFARTKEEAKQKTVELKDGKITDVFVKRKGAKFLRFAPVSSHQKVTFFIHSCLDAVQIQVRRDGKLLLSQNVEGIQQFQLRGKPKAKYLVRLKGNKKGASMLKILATTRPTKQSFPSLPEDTRIKAFDKLRTCSSATVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDIRKKSEKVLCKYFHSQNLQKAVTTETIKGLQPGKSYLLDVYVIGHGGHSVKYQSKVVKTRKFC", "length": 568 }, "evidence": [ { "id": "F6QPI1", "url": "https://omabrowser.org/oma/group/F6QPI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "nitric oxide mediated signal transduction", "id": "GO:0007263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007263", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell apoptotic process", "id": "GO:2000352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000352", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" }, { "name": "cellular response to fibroblast growth factor stimulus", "id": "GO:0044344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044344", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "F6QPI1", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QPI1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 568, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QPI1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QPI1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QPI1" }, { "id": "SM00060", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 324, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 201 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 322, "end_pos": 324 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QQ96-1", "uniprot_ac": "F6QQ96", "uniprot_id": "F6QQ96_BOVIN", "mass": { "chemical_mass": 70453.0, "monoisotopic_mass": 70453.0 }, "refseq": {}, "gene_names": [ { "name": "NUB1", "type": "recommended", "evidence": [ { "id": "F6QQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQ96" } ] } ], "protein_names": [ { "name": "NEDD8 ultimate buster 1", "type": "recommended", "evidence": [ { "id": "F6QQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQ96/entry#names_and_taxonomy" } ] }, { "name": "Negative regulator of ubiquitin-like proteins 1", "type": "synonym", "evidence": [ { "id": "F6QQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQ96/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QQ96", "url": "https://www.uniprot.org/uniprotkb/F6QQ96" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NUB1", "url": "https://www.uniprot.org/uniprotkb/F6QQ96", "locus": { "chromosome": "4", "start_pos": 113926882, "end_pos": 113890518, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004540", "url": "https://www.ensembl.org/id/ENSBTAG00000004540" } ] } } ], "crossref": [ { "id": "F6QQ96", "url": "https://alphafold.ebi.ac.uk/entry/F6QQ96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004540", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004540", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14293", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14293", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17062", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17062", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6QQ96", "url": "https://www.orthodb.org/?gene=F6QQ96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12948:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12948:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26285", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26285", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NXB6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXB6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QQ96", "url": "https://www.uniprot.org/uniprotkb/F6QQ96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QQ96-1", "url": "https://www.uniprot.org/uniprotkb/F6QQ96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQKKYLQSKLTQFLREDKIQLWKPPYTDENKEVGLALKDLAKKYSDKLECCENEVEEIMEEIRCKAVERGTGNEHYKTTGIATIEVFLPARLKKDRKNLLETHLHITGRELRSKIAETFGFQENYIKIVINKKQLQLGETLKEQGVTHNVKAMVLELKQSEEDVRKNVQVEEEKRNEAKLEEKRIQRTKRGLEILAERAAEMVVDPEATPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEHGIALPCLLDADRYFCECCTELLDTVDNYAVLQLDIVWCYFRLGQLECLDDAEKKLKLAQECFRKCYGENHQRLLHIKGNCGKEKVLFLRLYLLQGIRNYHSGNGEEAYENLNKARQLFKELYIDPSKVHNLMQLGFSAQEARLGLRACDGNVDHAAVHIANRREELDQIKKEEREKKKRRLENINHLKGMGYSMRAARQALHQAAGNLEEALKILLHNPQLWWLNDSAPESNNRQQSPSQEKIDQLVYMGFDAVAAKAALRVFRDNVQLAAQTLVHNGGRLPPDLQLSAEDSSSTPSTSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENIKSAAKKN", "length": 615, "header": "tr|F6QQ96-1|F6QQ96_BOVIN Isoform 1 of NEDD8 ultimate buster 1 OS=Bos taurus OX=9913 GN=NUB1 PE=4 SV=3 CANONICAL=F6QQ96-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXB6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB6/entry", "sequence": { "sequence": "MAQKKYLQSKLTQFLREDKIQLWKPPYTDENKEVGLALKDLAKKYSDKLECCENEVEEIMEEIRCKAVERGTGNEHYKTTGIATIEVFLPARLKKDRKNLLETHLHITGRELRSKIAETFGFQENYIKIVINKKQLQLGETLKEQGVTHNVKAMVLELKQSEEDVRKNVQVEEEKRNEAKLEEKRIQRTKRGLEILAERAEMVVDPEATPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEHGIALPCLLDADRYFCECCTELLDTVDNYAVLQLDIVWCYFRLGQLECLDDAEKKLKLAQECFRKCYGENHQRLLHIKGNCGKEKVLFLRLYLLQGIRNYHSGNGEEAYENLNKARQLFKELYIDPSKVHNLMQLGFSAQEARLGLRACDGNVDHAAVHIANRREELDQIKKEEREKKKRRLENINHLKGMGYSMRAARQALHQAAGNLEEALKILLHNPQLWWLNDSAPESNNRQQSPSQEKIDQLVYMGFDAVAAKAALRVFRDNVQLAAQTLVHNGGRLPPDLQLSAEDSSSTPSTSPSDSAGRCTSWWAKVGRGPHTLIWNFFGWRNKHAQKRHSCRSWPPPKLSYSRGSRRVEWSQRKQSGLDESGRAGG", "length": 625, "header": "tr|A0ABI0NXB6-1|A0ABI0NXB6_BOVIN Computationally mapped isoform of NEDD8 ultimate buster 1 OS=Bos taurus OX=9913 GN=NUB1 PE=4 SV=1 CANONICAL=F6QQ96-1" }, "locus": { "chromosome": "4", "start_pos": 113934283, "end_pos": 113893863, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139554.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139554.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104628.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104628.1" } ] } }, { "isoform_ac": "F6QQ96-1", "url": "https://www.uniprot.org/uniprotkb/F6QQ96/entry", "sequence": { "sequence": "MAQKKYLQSKLTQFLREDKIQLWKPPYTDENKEVGLALKDLAKKYSDKLECCENEVEEIMEEIRCKAVERGTGNEHYKTTGIATIEVFLPARLKKDRKNLLETHLHITGRELRSKIAETFGFQENYIKIVINKKQLQLGETLKEQGVTHNVKAMVLELKQSEEDVRKNVQVEEEKRNEAKLEEKRIQRTKRGLEILAERAAEMVVDPEATPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEHGIALPCLLDADRYFCECCTELLDTVDNYAVLQLDIVWCYFRLGQLECLDDAEKKLKLAQECFRKCYGENHQRLLHIKGNCGKEKVLFLRLYLLQGIRNYHSGNGEEAYENLNKARQLFKELYIDPSKVHNLMQLGFSAQEARLGLRACDGNVDHAAVHIANRREELDQIKKEEREKKKRRLENINHLKGMGYSMRAARQALHQAAGNLEEALKILLHNPQLWWLNDSAPESNNRQQSPSQEKIDQLVYMGFDAVAAKAALRVFRDNVQLAAQTLVHNGGRLPPDLQLSAEDSSSTPSTSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENIKSAAKKN", "length": 615, "header": "tr|F6QQ96-1|F6QQ96_BOVIN Isoform 1 of NEDD8 ultimate buster 1 OS=Bos taurus OX=9913 GN=NUB1 PE=4 SV=3 CANONICAL=F6QQ96-1" }, "locus": { "chromosome": "4", "start_pos": 113925910, "end_pos": 113893863, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005970.8", "url": "https://www.ensembl.org/id/ENSBTAT00000005970.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005970.8", "url": "https://www.ensembl.org/id/ENSBTAP00000005970.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000058", "evidence": [ { "database": "UniProtKB", "id": "F6QQ96", "url": "https://www.uniprot.org/uniprotkb/F6QQ96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QQ96-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 615, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QQ96-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QQ96" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQ96" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 374, "end_pos": 414, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 477, "end_pos": 479 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QQE8-1", "uniprot_ac": "F6QQE8", "uniprot_id": "F6QQE8_BOVIN", "mass": { "chemical_mass": 60742.0, "monoisotopic_mass": 60742.0 }, "refseq": {}, "gene_names": [ { "name": "CYP27A1", "type": "recommended", "evidence": [ { "id": "F6QQE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQE8" } ] } ], "protein_names": [ { "name": "Cytochrome P450 family 27 subfamily A member 1", "type": "synonym", "evidence": [ { "id": "F6QQE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQE8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QQE8", "url": "https://www.uniprot.org/uniprotkb/F6QQE8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CYP27A1", "url": "https://www.uniprot.org/uniprotkb/F6QQE8", "locus": { "chromosome": "2", "start_pos": 106782296, "end_pos": 106740008, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013489", "url": "https://www.ensembl.org/id/ENSBTAG00000013489" } ] } } ], "crossref": [ { "id": "F6QQE8", "url": "https://alphafold.ebi.ac.uk/entry/F6QQE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013489", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013489", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GPQTHVN", "url": "https://omabrowser.org/oma/group/GPQTHVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QQE8", "url": "https://www.orthodb.org/?gene=F6QQE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24279", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24279", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24279:SF123", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24279:SF123", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-193368", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193368", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-193775", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-193807", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-211976", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211976", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6QQE8", "url": "https://www.uniprot.org/uniprotkb/F6QQE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QQE8-1", "url": "https://www.uniprot.org/uniprotkb/F6QQE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRMGALGSARLRWALLGRRAALPGLGSFGARAKAAIPSALPAAQAAEAPGTGPGDRRLRSLDELSGPGQLRLLFQLLVQGYVLHLHQLQVLNKAKYGPIWINRVGPQMHVHLASAPLLEQVMRQEGKYPVRDDMKLWKEHRDQQGLSYGPFTTMGEQWYRLRQTLNQRMLKPAEAALYTDALNEVINDFMDQLKQLRAESASGDHVPDIAHQFYFFALEAISYILFEKRIGCLERSIPKDTETFVRSVGLMFHNSLFVTFLPTWTRPLLPFWKRYLDGWNTIFSFGKKLIDQKLEEIEAQLKTENPEKTQISGYLHFLLTSGQLSPREAEGSLPELLLAGVDTTSNTLTWALYHLSKNPEIQAALHKEVVGVVPAGQVPQHKDLARMPLLKAVLKETLRLYPVVPVNSRVVVDKEIEVGGFLFPKNTQFVLCHYVISRDPDIYPEPDSFQPQRWLRKNQPDALKTQHPFGSVPFGYGVRACLGRRIAELEMQLLLTRLIQHYEVVLAPETGEVTSVARIVLVPNKKVGLRFLQRQS", "length": 537, "header": "tr|F6QQE8-1|F6QQE8_BOVIN Isoform 1 of Cytochrome P450 family 27 subfamily A member 1 OS=Bos taurus OX=9913 GN=CYP27A1 PE=3 SV=1 CANONICAL=F6QQE8-1" }, "isoforms": [ { "isoform_ac": "F6QQE8-1", "url": "https://www.uniprot.org/uniprotkb/F6QQE8/entry", "sequence": { "sequence": "MNRMGALGSARLRWALLGRRAALPGLGSFGARAKAAIPSALPAAQAAEAPGTGPGDRRLRSLDELSGPGQLRLLFQLLVQGYVLHLHQLQVLNKAKYGPIWINRVGPQMHVHLASAPLLEQVMRQEGKYPVRDDMKLWKEHRDQQGLSYGPFTTMGEQWYRLRQTLNQRMLKPAEAALYTDALNEVINDFMDQLKQLRAESASGDHVPDIAHQFYFFALEAISYILFEKRIGCLERSIPKDTETFVRSVGLMFHNSLFVTFLPTWTRPLLPFWKRYLDGWNTIFSFGKKLIDQKLEEIEAQLKTENPEKTQISGYLHFLLTSGQLSPREAEGSLPELLLAGVDTTSNTLTWALYHLSKNPEIQAALHKEVVGVVPAGQVPQHKDLARMPLLKAVLKETLRLYPVVPVNSRVVVDKEIEVGGFLFPKNTQFVLCHYVISRDPDIYPEPDSFQPQRWLRKNQPDALKTQHPFGSVPFGYGVRACLGRRIAELEMQLLLTRLIQHYEVVLAPETGEVTSVARIVLVPNKKVGLRFLQRQS", "length": 537, "header": "tr|F6QQE8-1|F6QQE8_BOVIN Isoform 1 of Cytochrome P450 family 27 subfamily A member 1 OS=Bos taurus OX=9913 GN=CYP27A1 PE=3 SV=1 CANONICAL=F6QQE8-1" }, "locus": { "chromosome": "2", "start_pos": 106782108, "end_pos": 106740015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017935.8", "url": "https://www.ensembl.org/id/ENSBTAT00000017935.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017935.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017935.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-193368", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193368", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol" }, { "id": "R-BTA-193775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193775", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 24-hydroxycholesterol" }, { "id": "R-BTA-193807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193807", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 27-hydroxycholesterol" }, { "id": "R-BTA-211976", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211976", "resource": "Reactome", "description": "Endogenous sterols" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZKC1-1", "protein_name": "Cytochrome P450 family 27 subfamily A member 1", "gene_name": "CYP27A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGPSGRARRLLLPLRLRPPPPIGPEPPCRTGSSAAAAAAGPARLKGPAELPGPGLLRTFVWLFLRGYLLHTHRLQLMSRRIYGPIWKSTFGHYQNINIGSPVVLEQLLRQEGKYPMRSDMALWKEHRDTRRLPYGPFTEEGERWYRLRQVLNKRLLKPSEAVLYADAIGEVVSDLMVRLRDERSRSPSGVLVGDVANLLYRFALEGISYILFETRIGCLKQQVPPETQHFIDSINLMFKNSIFATVLPRWSRKVLPFWDRYLDSWDTIFAFGKRLIDRKMKELEGHVEKGKEVSQGYLSYLLASGHLSLDEVYGSVAELLLAGVDTTSNTLCWALYHLSRDLGIQDTLYQELKAVVPPDRFPGAEDIPKMPMLRAVIKETLRVYPVVPTNARVFYEKDIVIGDYLFPKNTLFVLAHYAMSHDETYFPEPERFLPQRWLRGHGSPHHPFSSIPFGYGVRACVGRRIAELEMHLALARIIQAYEVRPDPRGVEVTSVSRIVLVADKPINLEFIARPGAP", "length": 518 }, "evidence": [ { "id": "F6QQE8", "url": "https://omabrowser.org/oma/group/F6QQE8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AC58GF28-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "zgc:136333", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTSINDNNNSHFQNNSKLYDSTTGSEGLNKRLGFGFLRPTAAATGFRRAAGNAAAASVSVQDGHRKLKTEADLPEIKIFTMLYQMLFKGYLNSIHELQIYQKQVYGPLSKINSGNLQGISISSVELLEELLRKDEKYPCRGYMTLWTEHRDLRGIGYGPFTEEGEKWYKLRAVLNKRMLHPKDSLQYGDVVNAVITDFIKRIYYLREMSPTGDLVSNLTNELYRFSLEGIASILFETRIGCLEKEIPVETQEFINSIAQMFTYSMHVALLPNWTRNYFPFWQKYIDGWDGIFKFGTKMIDMKMEAIQKRVDTNQEVAGEYLTYLLSSGKMSSKDVYGSVSELLLAGVDTTSNTMLWALYLLSKDPAAQETLYQEVTKVLKDDRIPTAEEVNSMPFLKAVIKETLRLYPVVPVNSRLIAETEVVIGEYFFPKKTTFNLCHYAISHDEKVFPEPQKFKPERWLRDGRTRPNPFGSIPFGFGVRACVGRRIAELEMHLALARLIKLFEMRPDPTVGEVKANFRSVLVPNKKVNLHFVERQKTET", "length": 542 }, "evidence": [ { "id": "F6QQE8", "url": "https://omabrowser.org/oma/group/F6QQE8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P17178-1", "protein_name": "Sterol 26-hydroxylase, mitochondrial", "gene_name": "Cyp27a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVLSRMRLRWALLDTRVMGHGLCPQGARAKAAIPAALRDHESTEGPGTGQDRPRLRSLAELPGPGTLRFLFQLFLRGYVLHLHELQALNKAKYGPMWTTTFGTRTNVNLASAPLLEQVMRQEGKYPIRDSMEQWKEHRDHKGLSYGIFITQGQQWYHLRHSLNQRMLKPAEAALYTDALNEVISDFIARLDQVRTESASGDQVPDVAHLLYHLALEAICYILFEKRVGCLEPSIPEDTATFIRSVGLMFKNSVYVTFLPKWSRPLLPFWKRYMNNWDNIFSFGEKMIHQKVQEIEAQLQAAGPDGVQVSGYLHFLLTKELLSPQETVGTFPELILAGVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVVPFGKVPQNKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPSVFPEPESFQPHRWLRKREDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLSRLIQKYEVVLSPGMGEVKSVSRIVLVPSKKVSLRFLQRQ", "length": 533 }, "evidence": [ { "id": "F6QQE8", "url": "https://omabrowser.org/oma/group/F6QQE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02318-1", "protein_name": "Sterol 26-hydroxylase, mitochondrial", "gene_name": "CYP27A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAPGAGPGVRRRQRSLEEIPRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQRQC", "length": 531 }, "evidence": [ { "id": "F6QQE8", "url": "https://omabrowser.org/oma/group/F6QQE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBG1-1", "protein_name": "Sterol 26-hydroxylase, mitochondrial", "gene_name": "Cyp27a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"F6QTX4-1", "uniprot_ac": "F6QTX4", "uniprot_id": "F6QTX4_BOVIN", "mass": { "chemical_mass": 54348.0, "monoisotopic_mass": 54348.0 }, "refseq": { "ac": "NP_001422095", "name": "receptor-interacting serine/threonine-protein kinase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422095" }, "gene_names": [ { "name": "RIPK3", "type": "recommended", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "name": "RIPK3", "type": "synonym", "evidence": [ { "id": "NP_001422095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422095" } ] } ], "protein_names": [ { "name": "Receptor-interacting serine/threonine-protein kinase 3", "type": "recommended", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4/entry#names_and_taxonomy" } ] }, { "name": "RIP-like protein kinase 3", "type": "synonym", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4/entry#names_and_taxonomy" } ] }, { "name": "Receptor-interacting protein 3", "type": "synonym", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4/entry#names_and_taxonomy" } ] }, { "name": "receptor-interacting serine/threonine-protein kinase 3", "type": "synonym", "evidence": [ { "id": "NP_001422095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422095" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RIPK3", "url": "https://www.uniprot.org/uniprotkb/F6QTX4", "locus": { "chromosome": "10", "start_pos": 20837031, "end_pos": 20832541, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018422", "url": "https://www.ensembl.org/id/ENSBTAG00000018422" } ] } } ], "crossref": [ { "id": "F6QTX4", "url": "https://alphafold.ebi.ac.uk/entry/F6QTX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "507427", "url": "https://www.ncbi.nlm.nih.gov/gene/507427", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WDYVSGP", "url": "https://omabrowser.org/oma/group/WDYVSGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329:SF297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329:SF297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12721", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12721", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QTX4-1", "url": "https://www.uniprot.org/uniprotkb/F6QTX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSTLWPSGASAPLVPIEELENPELIGKGGFGSVFRAHHRSWGVEVAVKIVNSRAISREVKAMSSLRNTNVLPLLGVTEKLVWEYVSGPALVTPFMENGSLAVLLQPRCPRPWPLLCQLLQELVLGMCYLHSQNPVLLHRDLKPSNVLLDSELHAKVADFGLSTFQGGSQSGAGSGESGCTPAYLAPELLANINQKASRASDVYSFGILTWAVLAGREAEMPQTSLVREAVCERQIRPPLTELPPSGPETPGLEELTDLMQKCWSHEPQKRPSFQECRINTKKALDLVNKGDVSGRKMNAAVFMVKEFLSEHRGSNSPGLERTEIDSPRETTGSHDSLVSEMMNLNLEGCPSSVPEKCTNLLESIGVQREQVPPAWTAETSSDSTARPPQTPETLPFRTQNPCPTSAWTPGPGPQGSQGAERCDTNWPPRGPAPNLVPGPWFPTIFNCQGVQIGNNNRLIIQGGTALSTKGVAPGGVDRGPQCTPQGRSSKEGPQEPEAWSGP", "length": 504, "header": "tr|F6QTX4-1|F6QTX4_BOVIN Isoform 1 of Receptor-interacting serine/threonine-protein kinase 3 OS=Bos taurus OX=9913 GN=RIPK3 PE=3 SV=1 CANONICAL=F6QTX4-1" }, "isoforms": [ { "isoform_ac": "F6QTX4-1", "url": "https://www.uniprot.org/uniprotkb/F6QTX4/entry", "sequence": { "sequence": "MSGSTLWPSGASAPLVPIEELENPELIGKGGFGSVFRAHHRSWGVEVAVKIVNSRAISREVKAMSSLRNTNVLPLLGVTEKLVWEYVSGPALVTPFMENGSLAVLLQPRCPRPWPLLCQLLQELVLGMCYLHSQNPVLLHRDLKPSNVLLDSELHAKVADFGLSTFQGGSQSGAGSGESGCTPAYLAPELLANINQKASRASDVYSFGILTWAVLAGREAEMPQTSLVREAVCERQIRPPLTELPPSGPETPGLEELTDLMQKCWSHEPQKRPSFQECRINTKKALDLVNKGDVSGRKMNAAVFMVKEFLSEHRGSNSPGLERTEIDSPRETTGSHDSLVSEMMNLNLEGCPSSVPEKCTNLLESIGVQREQVPPAWTAETSSDSTARPPQTPETLPFRTQNPCPTSAWTPGPGPQGSQGAERCDTNWPPRGPAPNLVPGPWFPTIFNCQGVQIGNNNRLIIQGGTALSTKGVAPGGVDRGPQCTPQGRSSKEGPQEPEAWSGP", "length": 504, "header": "tr|F6QTX4-1|F6QTX4_BOVIN Isoform 1 of Receptor-interacting serine/threonine-protein kinase 3 OS=Bos taurus OX=9913 GN=RIPK3 PE=3 SV=1 CANONICAL=F6QTX4-1" }, "locus": { "chromosome": "10", "start_pos": 20836533, "end_pos": 20832679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053456.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053456.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052091.2", "url": "https://www.ensembl.org/id/ENSBTAP00000052091.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 406, "start_aa": "Thr", "end_pos": 406, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr406", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1SGQ6-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGVKLWHVGASAPLVPIEDLENPKFIGKGGFGTVFRAQHKTWGLDVAVKIVNSQAISREVKAMAGLHNSYVLLLLGITEKLEWDYVSGPALVTQFMENGSLAELLQPQCPRPWPLLCRLLQELVLGMCYLHSQDPVLLHRDLKPSNVLLDSELHAKLADFGLSTFQGGSQSRAESGESGCTPAYLAPELLADINRKASMASDVYSFGILMWAVLAGREAEVATQISLVREAVCERHVRPPLDELPQSGPENPGLEGLKDLMQRCWSHDPRNRPSFQDCRPNTQGALDLVMKQDVTCKKMNAAVSTVKEFLSEHKSSSSLLSVREPGLESPEMDGLRGSTGSHDSVVSEMMNSLNLEEYPSSVPEKCTNPPERIRAQKEQVQPTWTAEIPSDSTAQPPQTPETLPFMSQKPSHTSAWPPGPGPQENQGPERRGTNWSPMAPGPNPISGPWSSQLLYNQGVQIGNSNYMVIKGRTASSTRGPVPWGMKKGPQHK", "length": 493 }, "evidence": [ { "id": "F6QTX4", "url": "https://omabrowser.org/oma/group/F6QTX4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9QZL0-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "Ripk3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSVKLWPTGASAVPLVSREELKKLEFVGKGGFGVVFRAHHRTWNHDVAVKIVNSKKISWEVKAMVNLRNENVLLLLGVTEDLQWDFVSGQALVTRFMENGSLAGLLQPECPRPWPLLCRLLQEVVLGMCYLHSLNPPLLHRDLKPSNILLDPELHAKLADFGLSTFQGGSQSGSGSGSGSRDSGGTLAYLDPELLFDVNLKASKASDVYSFGILVWAVLAGREAELVDKTSLIRETVCDRQSRPPLTELPPGSPETPGLEKLKELMIHCWGSQSENRPSFQDCEPKTNEVYNLVKDKVDAAVSEVKHYLSQHRSSGRNLSAREPSQRGTEMDCPRETMVSKMLDRLHLEEPSGPVPGKCPERQAQDTSVGPATPARTSSDPVAGTPQIPHTLPFRGTTPGPVFTETPGPHPQRNQGDGRHGTPWYPWTPPNPMTGPPALVFNNCSEVQIGNYNSLVAPPRTTASSSAKYDQAQFGRGRGWQPFHK", "length": 486 }, "evidence": [ { "id": "F6QTX4", "url": "https://omabrowser.org/oma/group/F6QTX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCVKLWPSGAPAPLVSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRLLKEVVLGMFYLHDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVSTVKDFLSQLRSSNRRFSIPESGQGGTEMDGFRRTIENQHSRNDVMVSEWLNKLNLEEPPSSVPKKCPSLTKRSRAQEEQVPQAWTAGTSSDSMAQPPQTPETSTFRNQMPSPTSTGTPSPGPRGNQGAERQGMNWSCRTPEPNPVTGRPLVNIYNCSGVQVGDNNYLTMQQTTALPTWGLAPSGKGRGLQHPPPVGSQEGPKDPEAWSRPQGWYNHSGK", "length": 518 }, "evidence": [ { "id": "F6QTX4", "url": "https://omabrowser.org/oma/group/F6QTX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2P5-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "Ripk3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSVKLWLNGASSISLVGSEELENLGFVGKGGFGAVFRARHTAWNLDVAVKIVNSKKISREVKAMVNLRHENVLLLLGVTENLEWDYVYGPALVTGFMENGSLSGLLQPSCPRPWPLLCRLLEEVVLGMCYLHSLNPSLLHRDLKPSNVLLDPELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLAPELLDNDGKASKASDVYSFGVLVWTVLAGREAEVVDKTSLIRGAVCNRQRRPPLTELPPDSPETPGLEGLKELMTHCWSSEPKDRPSFQDCESKTNNVYILVQDKVDAAVSKVKHYLSQYRSSDTKLSARESSQKGTEVDCPRETIVYEMLDRLHLEEPSGSVPERLTSLTERRGKEASFGHATPAGTSSDTLAGTPQIPHTLPSRGTTPRPAFTETPGPDPQRNQGDGRNSNPWYTWNAPNPMTGLQSIVLNNCSEVQIGQHNCMSVQPRTAFPKKEPAQFGRGRGW", "length": 478 }, "evidence": [ { "id": "F6QTX4", "url": "https://omabrowser.org/oma/group/F6QTX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "regulation of T cell mediated cytotoxicity", "id": "GO:0001914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001914", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "amyloid fibril formation", "id": "GO:1990000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990000", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "spleen development", "id": "GO:0048536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048536", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "positive regulation of reactive oxygen species metabolic process", "id": "GO:2000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000379", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "T cell homeostasis", "id": "GO:0043029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043029", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "T cell differentiation in thymus", "id": "GO:0033077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033077", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "necroptotic signaling pathway", "id": "GO:0097527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097527", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "positive regulation of necroptotic process", "id": "GO:0060545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060545", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "regulation of type II interferon production", "id": "GO:0032649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032649", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "lymph node development", "id": "GO:0048535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048535", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "ripoptosome assembly involved in necroptotic process", "id": "GO:1901026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901026", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "regulation of activated T cell proliferation", "id": "GO:0046006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046006", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "regulation of activation-induced cell death of T cells", "id": "GO:0070235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070235", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation", "id": "GO:2000452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000452", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "execution phase of necroptosis", "id": "GO:0097528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097528", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase binding", "id": "GO:0120283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120283", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F6QTX4", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", 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"F6QVL1", "url": "https://alphafold.ebi.ac.uk/entry/F6QVL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023601", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023601", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15484:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15484:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73762", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73772", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73863", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6QVL1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVL1-1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGTPSGSAARFSCPPNFTATPPASEHSRFSLEALTGPDTELWLIQAPVDFAPDCLNGRLVPLSGSQIVKGKLAGKRHRYRVLSSSGPRAGGEATLLAPSAEAGGGLTCALAPQGSLRIFESPQESLTGTLLQSIPASPPPQIPPGLRPRFCAFGGSPPVTGPGSVLALKSLASGKRKKKRHLPEASVPQEAVNEHGALEVDTALGSLELDVGKKEKKHQLKELEATEPLATEPVAEMLEPPGTLSPSTTRKRKKKPKESVEMVKPETGMPESKEKTVEELEFRVKREPLEETVLSPRKKRKKQKEPGEMEPVEGTTVESQLQVKTEPQEEAIPLPSSKKKKKEKRYKGMREPGMEVMEPEVKPLELTGEVMEPDLPPDVQAQSEAALGSPKKRRKKEKQQNVMMQPGTEVVEPQAEGMEPELPGAAEPQAALASTKKKKKERGHLATEPGTEMTNPQGEMMEPELPDEGQPEARADPASTKKRKKQGQKSQVPETAPQEEMPEPPLNPESGQVAPKGQERKRKKKPQQDPMLQLRCKKLPLRFRLAFLLGKDSTPTCQPGGPRLPISQMGTLRPGGVT", "length": 579, "header": "tr|F6QVL1-1|F6QVL1_BOVIN Isoform 1 of DNA-directed RNA polymerase I subunit RPA34 OS=Bos taurus OX=9913 GN=POLR1G PE=3 SV=2 CANONICAL=F6QVL1-1" }, "isoforms": [ { "isoform_ac": "F6QVL1-1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1/entry", "sequence": { "sequence": "MAGTPSGSAARFSCPPNFTATPPASEHSRFSLEALTGPDTELWLIQAPVDFAPDCLNGRLVPLSGSQIVKGKLAGKRHRYRVLSSSGPRAGGEATLLAPSAEAGGGLTCALAPQGSLRIFESPQESLTGTLLQSIPASPPPQIPPGLRPRFCAFGGSPPVTGPGSVLALKSLASGKRKKKRHLPEASVPQEAVNEHGALEVDTALGSLELDVGKKEKKHQLKELEATEPLATEPVAEMLEPPGTLSPSTTRKRKKKPKESVEMVKPETGMPESKEKTVEELEFRVKREPLEETVLSPRKKRKKQKEPGEMEPVEGTTVESQLQVKTEPQEEAIPLPSSKKKKKEKRYKGMREPGMEVMEPEVKPLELTGEVMEPDLPPDVQAQSEAALGSPKKRRKKEKQQNVMMQPGTEVVEPQAEGMEPELPGAAEPQAALASTKKKKKERGHLATEPGTEMTNPQGEMMEPELPDEGQPEARADPASTKKRKKQGQKSQVPETAPQEEMPEPPLNPESGQVAPKGQERKRKKKPQQDPMLQLRCKKLPLRFRLAFLLGKDSTPTCQPGGPRLPISQMGTLRPGGVT", "length": 579, "header": "tr|F6QVL1-1|F6QVL1_BOVIN Isoform 1 of DNA-directed RNA polymerase I subunit RPA34 OS=Bos taurus OX=9913 GN=POLR1G PE=3 SV=2 CANONICAL=F6QVL1-1" }, "locus": { "chromosome": "18", "start_pos": 53032443, "end_pos": 53022156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032261.5", "url": "https://www.ensembl.org/id/ENSBTAT00000032261.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032197.5", "url": "https://www.ensembl.org/id/ENSBTAP00000032197.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" }, { "id": "R-BTA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-BTA-73772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73772", "resource": "Reactome", "description": "RNA Polymerase I Promoter Escape" }, { "id": "R-BTA-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6QVL1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F6QVL1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1" } ], "pmid": "" }, { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "F6QVL1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "F6QVL1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "F6QVL1", "url": "https://www.uniprot.org/uniprotkb/F6QVL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QVL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 579, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QVL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QVL1" } ], "lectin_list": [], "domain_list": [], 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N546-1", "uniprot_ac": "F1N546", "uniprot_id": "F1N546_BOVIN", "mass": { "chemical_mass": 53562.0, "monoisotopic_mass": 53562.0 }, "refseq": {}, "gene_names": [ { "name": "TMCC3", "type": "recommended", "evidence": [ { "id": "F1N546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N546" } ] } ], "protein_names": [ { "name": "Transmembrane and coiled-coil domain family 3", "type": "synonym", "evidence": [ { "id": "F1N546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N546/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N546", "url": "https://www.uniprot.org/uniprotkb/F1N546" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMCC3", "url": "https://www.uniprot.org/uniprotkb/F1N546", "locus": { "chromosome": "5", "start_pos": 24306950, "end_pos": 24493647, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014375", "url": "https://www.ensembl.org/id/ENSBTAG00000014375" } ] } } ], "crossref": [ { "id": "F1N546", "url": "https://alphafold.ebi.ac.uk/entry/F1N546", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014375", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014375", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509239", "url": "https://www.ncbi.nlm.nih.gov/gene/509239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "APHGMES", "url": "https://omabrowser.org/oma/group/APHGMES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LYP9", "url": "https://www.orthodb.org/?gene=A0A3Q1LYP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N546", "url": "https://www.orthodb.org/?gene=F1N546", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17613", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17613", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17613:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17613:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10267", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10267", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LT20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYP9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M763", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M763", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M763-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M763-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDB9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N546", "url": "https://www.uniprot.org/uniprotkb/F1N546", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N546-1", "url": "https://www.uniprot.org/uniprotkb/F1N546-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGSDTALTVDRTYSDPGRHHHCKRRVERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLNADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLDQYHRKLRELEQNGALRSAKDTAKDQLKDIPPSLKDAQAKSRTAPHSLESSKSGMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARVYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFAAGGSGALDSQGKLTAILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRCERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVNAKVLLGKCINVVLAFMTVILVCVSTIAKFISPMMKSRFHILGTFFAVTLFAIFCKNWDHILCAIERIIIPR", "length": 477, "header": "tr|F1N546-1|F1N546_BOVIN Isoform 1 of Transmembrane and coiled-coil domain family 3 OS=Bos taurus OX=9913 GN=TMCC3 PE=3 SV=1 CANONICAL=F1N546-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LT20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT20/entry", "sequence": { "sequence": "MTSCLFGKVERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLNADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLDQYHRKLRELEQNGALRSAKDTAKDQLKDIPPSLKDAQAKSRTAPHSLESSKSGMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARVYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFAAGGSGALDSQGKLTAILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRCERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVNAKVLLGKCINVVLAFMTVILVCVSTIAKFISPMMKSRFHILGTFFAVTLFAIFCKNWDHILCAIERIIIPR", "length": 459, "header": "tr|A0A3Q1LT20-1|F1N546_BOVIN Computationally mapped isoform of Transmembrane and coiled-coil domain family 3 OS=Bos taurus OX=9913 GN=TMCC3 PE=3 SV=1 CANONICAL=F1N546-1" }, "locus": { "chromosome": "5", "start_pos": 24320754, "end_pos": 24307876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079611.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079611.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063581.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063581.2" } ] } }, { "isoform_ac": "A0A3Q1LYP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYP9/entry", "sequence": { "sequence": "MIVWGRELHLPWNPKVWALLKLEDRCSPFQCGEWITSCSLSYVMLICQRKQPGSLTAKSCVERGGPRKRHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLNADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLDQYHRKLRELEQNGALRSAKDTAKDQLKDIPPSLKDAQAKSRTAPHSLESSKSGMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARVYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFAAGGSGALDSQGKLTAILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRCERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVNAKVLLGKCINVVLAFMTVILVCVSTIAKFISPMMKSRFHILGTFFAVTLFAIFCKNWDHILCAIERIIIPR", "length": 517, "header": "tr|A0A3Q1LYP9-1|A0A3Q1LYP9_BOVIN Computationally mapped isoform of Transmembrane and coiled-coil domain family 3 OS=Bos taurus OX=9913 GN=TMCC3 PE=3 SV=2 CANONICAL=F1N546-1" }, "locus": { "chromosome": "5", "start_pos": 24493646, "end_pos": 24307876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080243.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080243.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062730.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062730.2" } ] } }, { "isoform_ac": "A0A3Q1M763-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M763/entry", "sequence": { "sequence": "MRGRAMARKQQVERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLNADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLDQYHRKLRELEQNGALRSAKDTAKDQLKDIPPSLKDAQAKSRTAPHSLESSKSGMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARVYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFAAGGSGALDSQGKLTAILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRCERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVNAKVLLGKCINVVLAFMTVILVCVSTIAKFISPMMKSRFHILGTFFAVTLFAIFCKNWDHILCAIERIIIPR", "length": 462, "header": "tr|A0A3Q1M763-1|F1N546_BOVIN Computationally mapped isoform of Transmembrane and coiled-coil domain family 3 OS=Bos taurus OX=9913 GN=TMCC3 PE=3 SV=1 CANONICAL=F1N546-1" }, "locus": { "chromosome": "5", "start_pos": 24328171, "end_pos": 24307876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082094.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082094.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069604.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069604.2" } ] } }, { "isoform_ac": "A0A3Q1MDB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDB9/entry", "sequence": { "sequence": "MPLEQEGELVADPGLCSLMCGVVFERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLNADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLDQYHRKLRELEQNGALRSAKDTAKDQLKDIPPSLKDAQAKSRTAPHSLESSKSGMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARVYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFAAGGSGALDSQGKLTAILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRCERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVNAKVLLGKCINVVLAFMTVILVCVSTIAKFISPMMKSRFHILGTFFAVTLFAIFCKNWDHILCAIERIIIPR", "length": 474, "header": "tr|A0A3Q1MDB9-1|F1N546_BOVIN Computationally mapped isoform of Transmembrane and coiled-coil domain family 3 OS=Bos taurus OX=9913 GN=TMCC3 PE=3 SV=1 CANONICAL=F1N546-1" }, "locus": { "chromosome": "5", "start_pos": 24344582, "end_pos": 24307876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072513.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072513.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068920.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068920.2" } ] } }, { "isoform_ac": "F1N546-1", "url": "https://www.uniprot.org/uniprotkb/F1N546/entry", "sequence": { "sequence": "MPGSDTALTVDRTYSDPGRHHHCKRRVERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLNADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLDQYHRKLRELEQNGALRSAKDTAKDQLKDIPPSLKDAQAKSRTAPHSLESSKSGMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARVYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFAAGGSGALDSQGKLTAILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRCERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVNAKVLLGKCINVVLAFMTVILVCVSTIAKFISPMMKSRFHILGTFFAVTLFAIFCKNWDHILCAIERIIIPR", "length": 477, "header": "tr|F1N546-1|F1N546_BOVIN Isoform 1 of Transmembrane and coiled-coil domain family 3 OS=Bos taurus OX=9913 GN=TMCC3 PE=3 SV=1 CANONICAL=F1N546-1" }, "locus": { "chromosome": "5", "start_pos": 24377459, "end_pos": 24307876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019113.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019113.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019113.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019113.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XYW5-1", "protein_name": "Transmembrane and coiled-coil domain family 3", "gene_name": "TMCC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIPKNCTCIIFVLISLGFFFFYGDEAVSCSVFQSGKLRKMLLISMKLAAVERHDMNTLSLPLSIRRGGSDTNLNFDVPDGVLEFHKVKLSADSLKQKILKVTEQIKVEQTARDGNVAEYLKLVNSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLEQYHKKLKDIEQNGSSKTTKDTSKDNLKDIQHGKPRTSGHGTESNKSSVPGVSLTPPVFVFSKSREFANLIRNKFGSADNIAHLKNTLEEFRPETSSRTYGGSATIVAKPKYISDDECSSGTSGSADSNGNTSFGPATAGALDSQGKLSMILEELREIKETQSQLADDIENLKTQFKRDYGFISQMLQEERYRYERLEDQLNDLTDLHQHETANLKQELASIEEKVAYQAYERSRDVQEALESCQTRVSKLELHQQEQQAQQTETVNAKVLLGKCINVILAFMTVILVCVSTIAKFIAPMMKSRFHIICTFFAVTLLAIFCKNWDHIICAIERMIIPR", "length": 494 }, "evidence": [ { "id": "F1N546", "url": "https://omabrowser.org/oma/group/F1N546/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LNJ4-1", "protein_name": "Transmembrane and coiled-coil domain family 3", "gene_name": "Tmcc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLCGGGGGRRRNRLEGVLCALNQGSSTHPGTCRWDMVVSAEVKNLVPVYPVLELTMSQETSIHVAVCVRVERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLSADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVSSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLEQYHRKLREIEQNGATRSSKDISKDSLKEIQHSLKDAHVKSRTAPHCLESSKSSMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASPRAYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFGAGGASTLDSQGKLAIILEELREIKVTQAQLAEDIEALKVQFKREYGFISQTLQEERYRYERLEDQLHDLTELHQHETANLKQELASAEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQTLQTDAVNAKVLLGKCINVVLAFMTVILVCVSTLAKFVSPMMKSRSHILGTFFAVTLLAIFCKNWDHILCAIERIIIPR", "length": 521 }, "evidence": [ { "id": "F1N546", "url": "https://omabrowser.org/oma/group/F1N546/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R310-1", "protein_name": "Transmembrane and coiled-coil domain protein 3", "gene_name": "Tmcc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGSDTALTVDRTYSDPGRHHRCKSRVDRHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLNADSLRQKILKVTEQIKIEQTSRDGNVAEYLKLVSSADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLEQYHRKLREIEQNGVTRSSKDISKDSLKEIHHSLKDAHVKSRTAPHCLESSKSSMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASPRAYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFGAGGTSTLDSQGKIAKIMEELREIKVTQTQLAEDIEALKVQFKREYGFISQTLQEERYRYERLEDQLHDLTELHQHETANLKQELASAEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQTLQTDAVNAKVLLGKCINVVLAFMTVILVCVSTLAKFVSPMMKSRSHILGTFFAVTLLAIFCKNWDHILCAIERIIIPR", "length": 477 }, "evidence": [ { "id": "F1N546", "url": "https://omabrowser.org/oma/group/F1N546/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULS5-1", "protein_name": "Transmembrane and coiled-coil domain protein 3", "gene_name": "TMCC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGSDTALTVDRTYSYPGRHHRCKSRVERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLTADSLKQKILKVTEQIKIEQTSRDGNVAEYLKLVNNADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLEQYHRKLREIEQNGASRSSKDISKDHLKDIHRSLKDAHVKSRTAPHCMESSKSGMPGVSLTPPVFVFNKSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARAYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFGAGGASTLDSQGKLAVILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYRYERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLELHQQEQQALQTDTVNAKVLLGRCINVILAFMTVILVCVSTIAKFVSPMMKSRCHILGTFFAVTLLAIFCKNWDHILCAIERMIIPR", "length": 477 }, "evidence": [ { "id": "F1N546", "url": "https://omabrowser.org/oma/group/F1N546/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N546", "url": "https://www.uniprot.org/uniprotkb/F1N546" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1N546", "url": "https://www.uniprot.org/uniprotkb/F1N546" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1N546", "url": "https://www.uniprot.org/uniprotkb/F1N546" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1N546", "url": "https://www.uniprot.org/uniprotkb/F1N546" } ], "pmid": "" }, { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "F1N546", "url": "https://www.uniprot.org/uniprotkb/F1N546" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 270, "end_pos": 272 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"https://www.ncbi.nlm.nih.gov/protein/XP_005218830" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CBFA2T3", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8", "locus": { "chromosome": "18", "start_pos": 14050587, "end_pos": 14127692, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010927", "url": "https://www.ensembl.org/id/ENSBTAG00000010927" } ] } } ], "crossref": [ { "id": "F1N1Y8", "url": "https://alphafold.ebi.ac.uk/entry/F1N1Y8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010927", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010927", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523815", "url": "https://www.ncbi.nlm.nih.gov/gene/523815", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523815", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523815", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAYEMIT", "url": "https://omabrowser.org/oma/group/KAYEMIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LUS1", "url": "https://www.orthodb.org/?gene=A0A3Q1LUS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LYI7", "url": "https://www.orthodb.org/?gene=A0A3Q1LYI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N1Y8", "url": "https://www.orthodb.org/?gene=F1N1Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10379:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10379:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005218830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUS1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYI7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1Y8-1", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDSPAEVKTQPRATPPSMPPPPPAASQGATRHPSFTPHTNREDGPAMSLPHGRFHGCLKWSMVCLLMNGSSHSPTAISGAPSTPNGFSNGPATSCTAALSTQQLPPACGARQLSKLKRFLATLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQSPAQYLAQHEQALLDADASSPVDSSELLLEVNDNGKRRTPDRTKENGSDRDPLHPDHLSKRPCTLSPAQRYSPSNGLPHPPPPPHYRLEDMAMAHHFRDSYRHLDPRELRERHRQLAMHGSRPEEVIDHRLTEREWAEEWKHLNNLLNCIMDMAEKTRRSLTVLRRCQEADREELNHWIRRCSDVAEDSKKGPGPTARPLGSSVGTEGAQLDVHREFMPRTLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELISTERAKMERALAEARRQASEDALTVVNQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPAAAVAEPVPGQSDTATGLGPCLPPAAASPSEAGSTGPSRPGSPGPPGPLDAAPR", "length": 593, "header": "tr|F1N1Y8-1|F1N1Y8_BOVIN Isoform 1 of CBFA2/RUNX1 partner transcriptional co-repressor 3 OS=Bos taurus OX=9913 GN=CBFA2T3 PE=3 SV=3 CANONICAL=F1N1Y8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUS1/entry", "sequence": { "sequence": "MSRASPVLDSGPSASTSCSTPRGPRKGGPADRKEKATAMPDSPAEVKTQPRATPPSMPPPPPAASQGATRHPSFTPHTMMNGSSHSPTAISGAPSTPNGFSNGPATSCTAALSTQQLPPACGARQLSKLKRFLATLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQSPAQYLAQHEQALLDADASSPVDSSELLLEVNDNGKRRTPDRTKENGSDRDPLHPDHLSKRPCTLSPAQRYSPSNGLPHPPPPPHYRLEDMAMAHHFRDSYRHLDPRELRERHRQLAMHGSRPEEVIDHRLTEREWAEEWKHLNNLLNCIMDMAEKTRRSLTVLRRCQEADREELNHWIRRCSDVAEDSKKGPGPTARPLGSSVGTEGAQLDVHREFMPRTLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELISTERAKMERALAEARRQASEDALTVVNQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPAAAVAEPVPGQSDTATGLGPCLPPAAASPSEAGSTGPSRPGSPGPPGPLDAAPR", "length": 605, "header": "tr|A0A3Q1LUS1-1|A0A3Q1LUS1_BOVIN Computationally mapped isoform of CBFA2/RUNX1 partner transcriptional co-repressor 3 OS=Bos taurus OX=9913 GN=CBFA2T3 PE=3 SV=1 CANONICAL=F1N1Y8-1" }, "locus": { "chromosome": "18", "start_pos": 14127493, "end_pos": 14051591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084816.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084816.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060910.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060910.1" } ] } }, { "isoform_ac": "A0A3Q1LYI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI7/entry", "sequence": { "sequence": "MSRASPVLDSGPSASTSCSTPRGPRKGGPADRKEKATAMPDSPAEVKTQPRATPPSMPPPPPAASQGATRHPSFTPHTNREDGPAMSLPHGRFHGCLKWSMVCLLMNGSSHSPTAISGAPSTPNGFSNGPATSCTAALSTQQLPPACGARQLSKLKRFLATLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQSPAQYLAQHEQALLDADASSPVDSSELLLEVNDNGKRRTPDRTKENGSDRDPLHPDHLSKRPCTLSPAQRYSPSNGLPHPPPPPHYRLEDMAMAHHFRDSYRHLDPRELRERHRQLAMHGSRPEEVIDHRLTEREWAEEWKHLNNLLNCIMDMAEKTRRSLTVLRRCQEADREELNHWIRRCSDVAEDSKKGPGPTARPLGSSVGTEGAQLDVHREFMPRTLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELISTERAKMERALAEARRQASEDALTVVNQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPAAAVAEPVPGQSDTATGLGPCLPPAAASPSEAGSTGPSRPGSPGPPGPLDAAPR", "length": 631, "header": "tr|A0A3Q1LYI7-1|A0A3Q1LYI7_BOVIN Computationally mapped isoform of CBFA2/RUNX1 partner transcriptional co-repressor 3 OS=Bos taurus OX=9913 GN=CBFA2T3 PE=3 SV=1 CANONICAL=F1N1Y8-1" }, "locus": { "chromosome": "18", "start_pos": 14127493, "end_pos": 14051591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083635.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083635.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065834.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065834.1" } ] } }, { "isoform_ac": "F1N1Y8-1", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8/entry", "sequence": { "sequence": "MPDSPAEVKTQPRATPPSMPPPPPAASQGATRHPSFTPHTNREDGPAMSLPHGRFHGCLKWSMVCLLMNGSSHSPTAISGAPSTPNGFSNGPATSCTAALSTQQLPPACGARQLSKLKRFLATLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQSPAQYLAQHEQALLDADASSPVDSSELLLEVNDNGKRRTPDRTKENGSDRDPLHPDHLSKRPCTLSPAQRYSPSNGLPHPPPPPHYRLEDMAMAHHFRDSYRHLDPRELRERHRQLAMHGSRPEEVIDHRLTEREWAEEWKHLNNLLNCIMDMAEKTRRSLTVLRRCQEADREELNHWIRRCSDVAEDSKKGPGPTARPLGSSVGTEGAQLDVHREFMPRTLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELISTERAKMERALAEARRQASEDALTVVNQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPAAAVAEPVPGQSDTATGLGPCLPPAAASPSEAGSTGPSRPGSPGPPGPLDAAPR", "length": 593, "header": "tr|F1N1Y8-1|F1N1Y8_BOVIN Isoform 1 of CBFA2/RUNX1 partner transcriptional co-repressor 3 OS=Bos taurus OX=9913 GN=CBFA2T3 PE=3 SV=3 CANONICAL=F1N1Y8-1" }, "locus": { "chromosome": "18", "start_pos": 14070587, "end_pos": 14051591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014515.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014515.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014515.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014515.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 392, "start_aa": "Thr", "end_pos": 392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr392", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:523815", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523815", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XZH1-1", "protein_name": "CBFA2/RUNX1 translocation partner 3", "gene_name": "CBFA2T3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPGGTPRLEGHPFSKTGPDPAAPGAATMPDSPADVKTQPRSTPPNMPPPPPAVTQGATRHPSFTPSTNRDAVPPTFLPRGRFHGCLKWSMVCLLMNGSSHSPTAINGAPSTPNGFSNGPATSSSASLSTHQLPPACGARQLSKLKRFLTTLQQFGNDISPEIGERVRTLVLGLVNSTLTIEEFHAKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARMAKQSPAQYLAQHEQLLLDANASSPIDSSELLLEVSESGKRRTPDRTKENGLDRDPLHPEHLSKRPCTMSPAQRYSPSNGLSHPPNGLPHPPGPPPQHYRLEDMAMAHHYRDAYRHADPRERPRPAVHGARQEEVIDHRLTDREWAEEWKHLNNLLNCIMDMVEKTRRSLTVLRRCQEADREELNHWIRRYSDAEDMKKGSPPSARPHNSSSSSEAPQLDVHRDFAPRPLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASEDALTVINQQEDSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHVCGQTLQGLPAPSVPTAVGQPEAVPPMASSPSDAGSAGASRAGTPGTPAPLESASR", "length": 617 }, "evidence": [ { "id": "F1N1Y8", "url": "https://omabrowser.org/oma/group/F1N1Y8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A303-1", "protein_name": "CBFA2/RUNX1 partner transcriptional co-repressor 3", "gene_name": "Cbfa2t3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQASTTLESGALLPGPRGLHNGSPAHRKEKAAAMPDSPAEVKTQPRSTPPSMPPPPPTSSQGATRPPSFTPHTHGEDGPATSLPHGRFHGCLKWSMVCLLMNGSSHSPTAIHGAPSTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDASATSPVDSSELLLEVNENGKRKTPDRTKENGSDRDPLHPDHLSKRSCTLSPAQRCSPSNGLPHPTPPPPPHYRLEDMAMAHHFRDSYRHPDPRELRERHRPLAIPGSRQEEVIDHRLTEREWAEEWKHLNSLLNCIMDMAEKTRRSLTVLRRCQEADREELNHWIRCYSDSEEGKKGPTPISARSLNSCSGSEGSQLDVHRDFTPRTLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASEDALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPAAAVADPLPGQPDATASPSEAGSAGPSRPCSPGPPVPLDTAVPR", "length": 619 }, "evidence": [ { "id": "F1N1Y8", "url": "https://omabrowser.org/oma/group/F1N1Y8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O54972-1", "protein_name": "Transcriptional corepressor CBFA2T3", "gene_name": "Cbfa2t3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQASTTTLESGALLSGPRGLQYGSPAHRKEKAAAMPDSPAEVKTQPRSTPPSMPPPPPTSSQGATRPPSFTPHTHGEDGPATSLPHGRFHGCLKWSMVCLLMNGSSHSPTAIHGAPSTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHAKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDASATSPVDSSELLLEVNENGKRRTPDRTKENGSDRDPLHPDHLSKRSCTLSPAQRCSPSNGLPHPTPPPPPHYRLEDMAMAHHFRDSYRHPDPRELRERHRPLAIPGSRQEEVIDHRLTEREWAEEWKHLNSLLNCIMDMVEKTRRSLTVLRRCQEADREELNHWIRCYSDSEEGKKGPTPISARSLNSCSGPEGSQLDVHRDFTPRTLSGYMPEEIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASEDALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHKDWEKHHHVCGQSLQGPAAAVADPLPGQPDATASPSEAGSAGPSRPCSPGPPGPLDAAVPR", "length": 620 }, "evidence": [ { "id": "F1N1Y8", "url": "https://omabrowser.org/oma/group/F1N1Y8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75081-1", "protein_name": "Transcriptional corepressor CBFA2T3", "gene_name": "CBFA2T3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGPAPVDRKAKASAMPDSPAEVKTQPRSTPPSMPPPPPAASQGATRPPSFTPHTHREDGPATLPHGRFHGCLKWSMVCLLMNGSSHSPTAINGAPCTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDASASSPIDSSELLLEVNENGKRRTPDRTKENGSDRDPLHPEHLSKRPCTLNPAQRYSPSNGPPQPTPPPHYRLEDIAMAHHFRDAYRHPDPRELRERHRPLVVPGSRQEEVIDHKLTEREWAEEWKHLNNLLNCIMDMVEKTRRSLTVLRRCQEADREELNHWARRYSDAEDTKKGPAPAAARPRSSSAGPEGPQLDVPREFLPRTLTGYVPEDIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASEDALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHRDWEKHHHVCGQSLQGPTAVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAGPSRPGSPSPPGPLDTVPR", "length": 653 }, "evidence": [ { "id": "F1N1Y8", "url": "https://omabrowser.org/oma/group/F1N1Y8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "negative regulation of glycolytic process", "id": "GO:0045820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045820", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "regulation of aerobic respiration", "id": "GO:1903715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903715", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1N1Y8", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 496, "end_pos": 532, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Y8" }, { "id": "PS51119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TAFH", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 206, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 392 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4W4-1", "uniprot_ac": "F1N4W4", "uniprot_id": "F1N4W4_BOVIN", "mass": { "chemical_mass": 46893.0, "monoisotopic_mass": 46893.0 }, "refseq": { "ac": "XP_005217366", "name": "membrane cofactor protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217366" }, "gene_names": [ { "name": "CD46", "type": "recommended", "evidence": [ { "id": "F1N4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ] }, { "name": "CD46", "type": "synonym", "evidence": [ { "id": "XP_005217366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217366" } ] }, { "name": "MCP", "type": "synonym", "evidence": [ { "id": "XP_005217366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217366" } ] } ], "protein_names": [ { "name": "Membrane cofactor protein", "type": "recommended", "evidence": [ { "id": "F1N4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4W4/entry#names_and_taxonomy" } ] }, { "name": "membrane cofactor protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005217366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217366" } ] } ], "function": [ { "annotation": "Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MGH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGH4#function" }, { "database": "UniProtKB", "id": "PIRNR037971", "url": "https://www.uniprot.org/uniprotkb/PIRNR037971#function" }, { "database": "UniProtKB", "id": "A0A3Q1N570", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N570#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CD46", "url": "https://www.uniprot.org/uniprotkb/F1N4W4", "locus": {} } ], "crossref": [ { "id": "F1N4W4", "url": "https://alphafold.ebi.ac.uk/entry/F1N4W4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005397", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005397", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "280851", "url": "https://www.ncbi.nlm.nih.gov/gene/280851", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LW07", "url": "https://www.orthodb.org/?gene=A0A3Q1LW07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M3Z1", "url": "https://www.orthodb.org/?gene=A0A3Q1M3Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M522", "url": "https://www.orthodb.org/?gene=A0A3Q1M522", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MGH4", "url": "https://www.orthodb.org/?gene=A0A3Q1MGH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MT36", "url": "https://www.orthodb.org/?gene=A0A3Q1MT36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N570", "url": "https://www.orthodb.org/?gene=A0A3Q1N570", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N4W4", "url": "https://www.orthodb.org/?gene=F1N4W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N4W5", "url": "https://www.orthodb.org/?gene=F1N4W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF521", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF521", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46393:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46393:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-977606", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005217366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LW07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LW07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3Z1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M522", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M522", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M522-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M522-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MT36", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MT36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MT36-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MT36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N570", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N570", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N570-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N570-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5L5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLL0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4W4-1", "url": "https://www.uniprot.org/uniprotkb/F1N4W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4W5", "url": "https://www.uniprot.org/uniprotkb/F1N4W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4W5-1", "url": "https://www.uniprot.org/uniprotkb/F1N4W5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSHPGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGKAECSATYTTYQDKATTATEQMN", "length": 434, "header": "tr|F1N4W4-1|F1N4W4_BOVIN Isoform 1 of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=5 CANONICAL=F1N4W4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LW07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW07/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSHPGHPPRPTDASPPNGAEGLGAGYIVLVIVALLALDYCSACTAVFADRGRKG", "length": 396, "header": "tr|A0A3Q1LW07-1|F1N4W4_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=3 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75590028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074324.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074324.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061373.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061373.3" } ] } }, { "isoform_ac": "A0A3Q1M3Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3Z1/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSHPGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGIYVTGESHRQDILFLSEKR", "length": 430, "header": "tr|A0A3Q1M3Z1-1|A0A3Q1M3Z1_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=2 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75587064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086249.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086249.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062932.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062932.2" } ] } }, { "isoform_ac": "A0A3Q1M522-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M522/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSHPGHPPRPTDASPPNGAEGLGAGYIVLVIVALLALDYCSACTAVFADRGRKG", "length": 410, "header": "tr|A0A3Q1M522-1|A0A3Q1M522_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=3 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75590028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082939.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082939.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063377.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063377.3" } ] } }, { "isoform_ac": "A0A3Q1MGH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGH4/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKDSKPTSPTMTSGLSHPGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGIYVTGESHRQDILFLSEKR", "length": 380, "header": "tr|A0A3Q1MGH4-1|F1N4W4_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=1 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75587064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076400.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076400.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068115.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068115.1" } ] } }, { "isoform_ac": "A0A3Q1MT36-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MT36/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSDSKPTSPTMTSGLSHPGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGIYVTGESHRQDILFLSEKR", "length": 416, "header": "tr|A0A3Q1MT36-1|F1N4W4_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=2 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75587064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085012.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085012.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073354.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073354.2" } ] } }, { "isoform_ac": "A0A3Q1N570-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N570/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGKAECSATYTTYQDKATTATEQMN", "length": 390, "header": "tr|A0A3Q1N570-1|A0A3Q1N570_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=2 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75584467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073079.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073079.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065225.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065225.2" } ] } }, { "isoform_ac": "A0AAA9T5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5L5/entry", "sequence": { "sequence": "ARGNQLFPASRSSFRVGPQEGGARGSQGAELEAVRVPRTRGTPRSWAGPAGLWEGGRLPIGPAPFSGVTSALGAPRGSGCAAGLGCPRRRCVRVLYRGELDSARSLRSSLGCPAGLPENEGVLHPAEGAAPPPRKTGFFWALRLGASAGAAAPAAHVLRYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGIYVTGESHRQDILFLSEKR", "length": 385, "header": "tr|A0AAA9T5L5-1|F1N4W4_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=1 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75621291, "end_pos": 75587064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101405.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101405.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094058.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094058.1" } ] } }, { "isoform_ac": "A0AAF6DLL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLL0/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGIYVTGESHRQDILFLSEKR", "length": 400, "header": "tr|A0AAF6DLL0-1|F1N4W4_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=1 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75587064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065728.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065728.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054031.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054031.3" } ] } }, { "isoform_ac": "F1N4W4-1", "url": "https://www.uniprot.org/uniprotkb/F1N4W4/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSHPGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGKAECSATYTTYQDKATTATEQMN", "length": 434, "header": "tr|F1N4W4-1|F1N4W4_BOVIN Isoform 1 of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=5 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75584467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007108.8", "url": "https://www.ensembl.org/id/ENSBTAT00000007108.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007108.8", "url": "https://www.ensembl.org/id/ENSBTAP00000007108.8" } ] } }, { "isoform_ac": "F1N4W5-1", "url": "https://www.uniprot.org/uniprotkb/F1N4W5/entry", "sequence": { "sequence": "MRASCTPLKAPLRRPERLASSGRFAWVLLLAPLLLLPTSSDACDDPPRFVSMKPQGTLKPSYSPGEQIVYECRLGFQPVTPGQVLALVCQDNNTWSSLQEGCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSGHPPRPTDASPPNGAEGLGAGYIVLVIVAVLIGVGLLLCLYCCFCRQRKKGIYVTGESHRQDILFLSEKR", "length": 414, "header": "tr|F1N4W5-1|F1N4W5_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=CD46 PE=4 SV=4 CANONICAL=F1N4W4-1" }, "locus": { "chromosome": "16", "start_pos": 75620936, "end_pos": 75587064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007107.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007107.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007107.6", "url": "https://www.ensembl.org/id/ENSBTAP00000007107.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 80, "start_aa": "Thr", "end_pos": 80, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr80", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" }, { "name": "inner acrosomal membrane", "id": "GO:0002079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002079", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" }, { "name": "negative regulation of complement activation, classical pathway", "id": "GO:0045959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045959", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" }, { "name": "T cell mediated immunity", "id": "GO:0002456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002456", "evidence": [ { "database": "UniProtKB", "id": "F1N4W4", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4W4" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 104, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 80, 367 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 158, "end_pos": 160 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5Z0-1", "uniprot_ac": "F1N5Z0", "uniprot_id": "F1N5Z0_BOVIN", "mass": { "chemical_mass": 40329.0, "monoisotopic_mass": 40329.0 }, "refseq": {}, "gene_names": [ { "name": "AQP5", "type": "recommended", "evidence": [ { "id": "F1N5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0" } ] } ], "protein_names": [ { "name": "Aquaporin-5", "type": "recommended", "evidence": [ { "id": "F1N5Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Aquaporins form homotetrameric transmembrane channels, with each monomer independently mediating water transport across the plasma membrane along its osmotic gradient. Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SS68", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS68#function" }, { "database": "UniProtKB", "id": "ARBA00049571", "url": "https://www.uniprot.org/uniprotkb/ARBA00049571#function" }, { "database": "UniProtKB", "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AQP5", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0", "locus": { "chromosome": "5", "start_pos": 29897981, "end_pos": 29913535, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000026813", "url": "https://www.ensembl.org/id/ENSBTAG00000026813" } ] } } ], "crossref": [ { "id": "F1N5Z0", "url": "https://alphafold.ebi.ac.uk/entry/F1N5Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000026813", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026813", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00333", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00333", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FWVGPIS", "url": "https://omabrowser.org/oma/group/FWVGPIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LWN9", "url": "https://www.orthodb.org/?gene=A0A3Q1LWN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MJS9", "url": "https://www.orthodb.org/?gene=A0A3Q1MJS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N5Z0", "url": "https://www.orthodb.org/?gene=F1N5Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19139:SF113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19139:SF113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19139:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19139:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-432047", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432047", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29667", "url": "https://www.rhea-db.org/rhea/29667", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LWN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS68", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS68-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF82", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF82-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5Z0-1", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGSQPAGPVYTAGLVTWPQRACGCPGGGARGAGGAAALKFPPCVQCWPPGVGAAHCPPGPAPPRAACLVYSAPPQAPRHVVSHAAGTRDCAGTRDCAAPPSQPPTPCTTASRTGDPCGDCCKTMKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPSVLQISLAFGLAIGTMAQALGPVSGGHMNPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAAILYGLAPYNARGNLAVNALNNNTTAGQAVVAEMILTFQLALCVFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPSVIMNRFSSAHWVFWVGPIVGAAVAAIIYFYLLFPHSLSLSDRAAILKGTYEPDEDWEESQEERKKTMELTAH", "length": 389, "header": "tr|F1N5Z0-1|F1N5Z0_BOVIN Isoform 1 of Aquaporin-5 OS=Bos taurus OX=9913 GN=AQP5 PE=1 SV=3 CANONICAL=F1N5Z0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LWN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWN9/entry", "sequence": { "sequence": "MRGSQPAGPVYTAGLVTWPQRACGCPGGGARGAGGAAALKFPPCVQCWPPGVGAAHCPPGPAPPRAACLVYSAPPQAPRHVVSHAAGTRDCAGTRDCAAPPSQPPTPCTTASRTGDPCGDCCKTMKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPSVLQISLAFGLAIGTMAQALGPVSGGHMNPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAAILYGLAPYNARGNLAVNALNNNTTAGQAVVAEMILTFQLALCVFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPSVIMNRFSSAHWIAITFNLATAVIVQITWKASGAHVNPAVTLAFLVGSHISLPRAVAYVAAQLAGATAGAALLYGVTPGDIRENFGVNMVRSSTSTGQAVAVELILTLQLVLCVFASTDSRQTTGSPAATIGASVAVGHLIGIYFTGCSMNPARSFGSAVIVGKFEVHWIFWVGPLTGAVLASLIYNFILFPDTKTLAQRLAILTGSAEMEKMEGEEPQKKETQANSEDTEMETVCQVA", "length": 555, "header": "tr|A0A3Q1LWN9-1|A0A3Q1LWN9_BOVIN Computationally mapped isoform of Aquaporin 5 OS=Bos taurus OX=9913 GN=AQP5 PE=3 SV=1 CANONICAL=F1N5Z0-1" }, "locus": { "chromosome": "5", "start_pos": 29913336, "end_pos": 29898985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085930.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085930.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065116.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065116.1" } ] } }, { "isoform_ac": "A0A3Q1MJS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJS9/entry", "sequence": { "sequence": "MRGSQPAGPVYTAGLVTWPQRACGCPGGGARGAGGAAALKFPPCVQCWPPGVGAAHCPPGPAPPRAACLVYSAPPQAPRHVVSHAAGTRDCAGTRDCAAPPSQPPTPCTTASRTGDPCGDCCKTMKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPSVLQISLAFGLAIGTMAQALGPVSGGHMNPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAAILYGLAPYNARGNLAVNAIYFTGCSMNPARSFGPSVIMNRFSSAHWIAITFNLATAVIVQITWKASGAHVNPAVTLAFLVGSHISLPRAVAYVAAQLAGATAGAALLYGVTPGDIRENFGVNMVRSSTSTGQAVAVELILTLQLVLCVFASTDSRQTTGSPAATIGASVAVGHLIGIYFTGCSMNPARSFGSAVIVGKFEVHWIFWVGPLTGAVLASLIYNFILFPDTKTLAQRLAILTGSAEMEKMEGEEPQKKETQANSEDTEMETVCQVA", "length": 500, "header": "tr|A0A3Q1MJS9-1|F1N5Z0_BOVIN Computationally mapped isoform of Aquaporin-5 OS=Bos taurus OX=9913 GN=AQP5 PE=1 SV=1 CANONICAL=F1N5Z0-1" }, "locus": { "chromosome": "5", "start_pos": 29913336, "end_pos": 29898985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067400.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067400.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071068.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071068.1" } ] } }, { "isoform_ac": "A0AAA9SS68-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS68/entry", "sequence": { "sequence": "MRGSQPAGPVYTAGLVTWPQRACGCPGGGARGAGGAAALKFPPCVQCWPPGVGAAHCPPGPAPPRAACLVYSAPPQAPRHVVSHAAGTRDCAGTRDCAAPPSQPPTPCTTASRTGDPCGDCCKTMKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPSVLQISLAFGLAIGTMAQALGPVSGGHMNPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAAILYGLAPYNARGNLAVNAIYFTGCSMNPARSFGPSVIMNRFSSAHWVRSSTSTGQAVAVELILTLQLVLCVFASTDSRQTTGSPAATIGASVAVGHLIGIYFTGCSMNPARSFGSAVIVGKFEVHWIFWVGPLTGAVLASLIYNFILFPDTKTLAQRLAILTGSAEMEKMEGEEPQKKETQANSEDTEMETVCQVA", "length": 423, "header": "tr|A0AAA9SS68-1|F1N5Z0_BOVIN Computationally mapped isoform of Aquaporin-5 OS=Bos taurus OX=9913 GN=AQP5 PE=1 SV=1 CANONICAL=F1N5Z0-1" }, "locus": { "chromosome": "5", "start_pos": 29913336, "end_pos": 29898985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132985.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132985.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086949.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086949.1" } ] } }, { "isoform_ac": "A0AAA9TF82-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF82/entry", "sequence": { "sequence": "MRGSQPAGPVYTAGLVTWPQRACGCPGGGARGAGGAAALKFPPCVQCWPPGVGAAHCPPGPAPPRAACLVYSAPPQAPRHVVSHAAGTRDCAGTRDCAAPPSQPPTPCTTASRTGDPCGDCCKTMKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPSVLQISLAFGLAIGTMAQALGPVSGGHMNPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAAILYGLAPYNARGNLAVNAVRSSTSTGQAVAVELILTLQLVLCVFASTDSRQTTGSPAATIGASVAVGHLIGIYFTGCSMNPARSFGSAVIVGKFEVHWIFWVGPLTGAVLASLIYNFILFPDTKTLAQRLAILTGSAEMEKMEGEEPQKKETQANSEDTEMETVCQVA", "length": 395, "header": "tr|A0AAA9TF82-1|F1N5Z0_BOVIN Computationally mapped isoform of Aquaporin-5 OS=Bos taurus OX=9913 GN=AQP5 PE=1 SV=1 CANONICAL=F1N5Z0-1" }, "locus": { "chromosome": "5", "start_pos": 29913336, "end_pos": 29898985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103305.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103305.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094806.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094806.1" } ] } }, { "isoform_ac": "F1N5Z0-1", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0/entry", "sequence": { "sequence": "MRGSQPAGPVYTAGLVTWPQRACGCPGGGARGAGGAAALKFPPCVQCWPPGVGAAHCPPGPAPPRAACLVYSAPPQAPRHVVSHAAGTRDCAGTRDCAAPPSQPPTPCTTASRTGDPCGDCCKTMKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPSVLQISLAFGLAIGTMAQALGPVSGGHMNPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAAILYGLAPYNARGNLAVNALNNNTTAGQAVVAEMILTFQLALCVFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPSVIMNRFSSAHWVFWVGPIVGAAVAAIIYFYLLFPHSLSLSDRAAILKGTYEPDEDWEESQEERKKTMELTAH", "length": 389, "header": "tr|F1N5Z0-1|F1N5Z0_BOVIN Isoform 1 of Aquaporin-5 OS=Bos taurus OX=9913 GN=AQP5 PE=1 SV=3 CANONICAL=F1N5Z0-1" }, "locus": { "chromosome": "5", "start_pos": 29913336, "end_pos": 29909787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038334.6", "url": "https://www.ensembl.org/id/ENSBTAT00000038334.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038149.5", "url": "https://www.ensembl.org/id/ENSBTAP00000038149.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-432047", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432047", "resource": "Reactome", "description": "Passive transport by Aquaporins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P9U9-1", "protein_name": "Aquaporin-5", "gene_name": "AQP5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKREILTLAFARAVFVEFISTLIFVFIGLGSALKWPSALPSILQISLAFGLAIGTLVQAFGHISGAHINPAVTIAFFVGNQISFLRTLFYVIAQLVGAIAGAGILYGVTPANTRGNLAINSLNNNTTPGQAVVVEMILTFQLAACIFASTDNRRNGNVGSPALSIGLSVAVGHLVGIYFTGCSMNPARSFGPAVIVRKFSSTHWVFWVGPILGACLAALLYFYILVPYCMNMSDRVAIVKGTYESEEEWEEQREERKKSMELTPP", "length": 265 }, "evidence": [ { "id": "F1N5Z0", "url": "https://omabrowser.org/oma/group/F1N5Z0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A8W649-1", "protein_name": "Aquaporin-5", "gene_name": "AQP5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKEVCSLAFLKAVFAEFLATLIFVFFGLASALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAVFYVVAQLVGAIAGAGILYGLAPGNARGNLAVNSLNNNTTPGQAVVVEMILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAAVAAILYFYLLFPNSLSLSERVAVVKGTYESEEDWEEQREERKKTMELTAH", "length": 265 }, "evidence": [ { "id": "F1N5Z0", "url": "https://omabrowser.org/oma/group/F1N5Z0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HX60-1", "protein_name": "Aquaporin-5", "gene_name": "Aqp5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKKEVCSVAFFKAVFAEFLATLIFVFFGLGSALKWPSALPSILQISIAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAVFYVAAQLVGAIAGAGLLYWLAPTNARGNLAVNALSNSTTPGKAMVVELILTFQLALCIFSSTDARRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMDRFSPSHWVFWVGPIVGAILAAILYFYLLFPSSLSLSDRVAVVKGTYEPEEDWEEHREERKKSIELTAH", "length": 265 }, "evidence": [ { "id": "F1N5Z0", "url": "https://omabrowser.org/oma/group/F1N5Z0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P47864-1", "protein_name": "Aquaporin-5", "gene_name": "Aqp5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKEVCSLAFFKAVFAEFLATLIFVFFGLGSALKWPSALPTILQISIAFGLAIGTLAQALGPVSGGHINPAITLALLIGNQISLLRAVFYVAAQLVGAIAGAGILYWLAPLNARGNLAVNALNNNTTPGKAMVVELILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAMLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEEDWEDHREERKKTIELTAH", "length": 265 }, "evidence": [ { "id": "F1N5Z0", "url": "https://omabrowser.org/oma/group/F1N5Z0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P55064-1", "protein_name": "Aquaporin-5", "gene_name": "AQP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYEPDEDWEEQREERKKTMELTTR", "length": 265 }, "evidence": [ { "id": "F1N5Z0", "url": "https://omabrowser.org/oma/group/F1N5Z0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FGL2-1", "protein_name": "Aquaporin TIP2-3", "gene_name": "TIP2-3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKIEVGSVGDSFSVSSLKAYLSEFIATLLFVFAGVGSAVAFAKLTSDGALDPAGLVAIAIAHAFALFVGVSIAANISGGHLNPAVTLGLAIGGNITLITGFFYWIAQCLGSIVACLLLVFVTNGKSVPTHGVSAGLGAVEGVVMEIVVTFALVYTVYATAADPKKGSLGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGDLSQIWIYWVGPLVGGALAGLIYGDVFIGSYEAVETREIRV", "length": 250 }, "evidence": [ { "id": "F1N5Z0", "url": "https://omabrowser.org/oma/group/F1N5Z0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WTY4-1", "protein_name": "Aquaporin-5", "gene_name": "Aqp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKEVCSVAFFKAVFAEFLATLIFVFFGLGSALKWPSALPTILQISIAFGLAIGTLAQALGPVSGGHINPAITLALLIGNQISLLRAIFYVAAQLVGAIAGAGILYWLAPGNARGNLAVNALSNNTTPGKAVVVELILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAVLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEEDWEDHREERKKTIELTAH", "length": 265 }, "evidence": [ { "id": "F1N5Z0", "url": "https://omabrowser.org/oma/group/F1N5Z0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "water transport", "id": "GO:0006833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006833", "evidence": [ { "database": "UniProtKB", "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0" } ], "pmid": "" }, { "name": "carbon dioxide transport", "id": "GO:0015670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015670", "evidence": [ { "database": "UniProtKB", "id": "F1N5Z0", "url": "https://www.uniprot.org/uniprotkb/F1N5Z0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "water channel activity", "id": "GO:0015250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015250", "evidence": [ { "database": "UniProtKB", 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"header": "tr|F1N664-1|F1N664_BOVIN Isoform 1 of Dual specificity mitogen-activated protein kinase kinase 7 OS=Bos taurus OX=9913 GN=MAP2K7 PE=3 SV=4 CANONICAL=F1N664-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF7/entry", "sequence": { "sequence": "MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPTLQLPLANDGGSRSPSSESSPQHPTPPARPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKRYETLEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFSRGQMGLPGPSPFPSWDQPAVHVPPPTDTVNGRQQAASSLAIYSVVTSGLGRPPGVGREPPFPAPSHTALSPPPPPCTHAPWLHLPLCHFPLYLSGFPRLPPHLCLSPGPGPATPGGDPWVHLGLWPVMSQLAGALPPAGGLDIVTAAGPGLVSLSLSLISGGPFWSLLYFIVLGGVFGGGGRRRACSHGLCWYLQKLLPKSCLAACGGSPPNRCGYWGAGLGAEPWGLMLPPGRD", "length": 654, "header": "tr|A0A3Q1LMF7-1|A0A3Q1LMF7_BOVIN Computationally mapped isoform of Dual specificity mitogen-activated protein kinase kinase 7 OS=Bos taurus OX=9913 GN=MAP2K7 PE=3 SV=2 CANONICAL=F1N664-1" }, "locus": { "chromosome": "7", "start_pos": 16671046, "end_pos": 16662615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073638.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073638.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058048.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058048.2" } ] } }, { "isoform_ac": "A0AAA9TXR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXR1/entry", "sequence": { "sequence": "MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPTLQLPLANDGGSRSPSSESSPQHPTPPARPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFESFVKDCLTKDHRKRPKYNKLLEHSFIKRYETLEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFR", "length": 395, "header": "tr|A0AAA9TXR1-1|F1N664_BOVIN Computationally mapped isoform of Dual specificity mitogen-activated protein kinase kinase 7 OS=Bos taurus OX=9913 GN=MAP2K7 PE=3 SV=2 CANONICAL=F1N664-1" }, "locus": { "chromosome": "7", "start_pos": 16670172, "end_pos": 16662615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103047.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103047.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103445.2", "url": "https://www.ensembl.org/id/ENSBTAP00000103445.2" } ] } }, { "isoform_ac": "F1N664-1", "url": "https://www.uniprot.org/uniprotkb/F1N664/entry", "sequence": { "sequence": "MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPIIVITLSPAPAPSQRAALQLPLANDGGSRSPSSESSPQHPTPPARPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKRYETLEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFR", "length": 435, "header": "tr|F1N664-1|F1N664_BOVIN Isoform 1 of Dual specificity mitogen-activated protein kinase kinase 7 OS=Bos taurus OX=9913 GN=MAP2K7 PE=3 SV=4 CANONICAL=F1N664-1" }, "locus": { "chromosome": "7", "start_pos": 16670172, "end_pos": 16662615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014063.8", "url": "https://www.ensembl.org/id/ENSBTAT00000014063.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014063.7", "url": "https://www.ensembl.org/id/ENSBTAP00000014063.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:787278", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787278", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "JUN kinase kinase activity", "id": "GO:0008545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008545", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "MAP kinase activity", "id": "GO:0004707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004707", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "cellular response to interleukin-1", "id": "GO:0071347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071347", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" }, { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "F1N664", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MWN2-1", "A0AAF6DMB3-1", "E1BI01-1", "A0AAA9TQL1-1", "F1MQH2-1", "F1N781-1", "F6QXU6-1", "A0A3Q1MKW9-1", "A0A3Q1M0U5-1", "F6S1J8-1", "A5D791-1", "F1N664-1", "E1BMP9-1", "F1MS00-1", "P43481-1", "A0A3Q1LR28-1", "A0A3Q1LVP1-1", "Q06807-1", "A0AAA9TD48-1", "Q5E9X2-1", "Q05688-1", "Q17R13-1", "E1BG90-1", "Q0VBZ0-1", "F1N758-1", "A0A3Q1LTC6-1", "A0A3Q1LNU2-1", "F1N1Q0-1", "A0A3Q1MHB0-1", "A0AAA9SN20-1", "A0AAA9TMY2-1", "A0A3Q1LI98-1", "E1BJ31-1", "A0A3Q1LRR9-1", "F1MX49-1", "A0A3Q1MHG9-1", "A0JNB0-1", "E1BER5-1", "E1BIM8-1", "E1BNE0-1", "A0A3Q1LT44-1", "A0A3Q1MJG0-1", "F1MII5-1", "F1N0D3-1", "F1N261-1", "F1N759-1", "F1N780-1", "F1MC14-1", "F1N3R6-1", "A0ABI0P1V8-1", "A0A3Q1LUE0-1", "F1MFH7-1", "F1MNW2-1", "A0AAA9SPC9-1", "F1N381-1", "F1MS29-1", "G1K218-1", "Q4TVR5-1", "A0AAA9SXH6-1", "E1BJS9-1", "A0AAA9SBR4-1", "F1MKR1-1", "F1MN51-1", "E1BCZ6-1", "E1BEL4-1", "F1MCX4-1", "F1N6J0-1", "Q3SZJ2-1", "Q769I5-1", "Z4YHD9-1", "Q06805-1", "Q3SX21-1", "A0A3Q1MAM7-1", "E1BPB5-1", "A0A3Q1MF99-1", "A0AAA9SA57-1", "A0AAA9TAT1-1", "A0AAA9THG2-1", "F1MC23-1", "A0AAA9SVL9-1", "F1MRU0-1", "A0AAA9T042-1", "E1BKP7-1", "E1BNA8-1", "F1ML02-1", "E1BPI3-1", "A0AAA9SW95-1", "G3X680-1", "A0AAA9TRY4-1", "A0A3Q1MEZ6-1", "E1B9H4-1", "E1B6X6-1", "E1B9Q2-1", "E1BPP1-1", "F1N6H6-1", "A0ABI0NRQ5-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = 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{ "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MAM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MAM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAM7" } ] } ] }, { "uniprot_ac": "A0A3Q1MD82", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MF99", "gene_name": "TXK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF99" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1MF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF99" } ] } ] }, { "uniprot_ac": "A0A3Q1MHB0", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": 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"uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SA57", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] } ] }, { "uniprot_ac": "A0AAA9SBR4", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SN20", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SPC9", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVL9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TMY2", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TQL1", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B6X6", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9H4", "gene_name": "PKDCC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BER5", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F1N6H6", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] } ] }, { "uniprot_ac": "F1N6J0", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N780", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] } ] }, { "uniprot_ac": "F1N781", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QXU6", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "F6S1J8", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] } ] }, { "uniprot_ac": "G1K218", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G3X680", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q05688", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] } ] }, { "uniprot_ac": "Q06805", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] } ] }, { "uniprot_ac": "Q06807", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q769I5", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q769I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q769I5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q769I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q769I5" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", 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{ "id": "A0A3Q1M6S3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MZC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MZC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STT2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MD74", "url": "https://www.uniprot.org/uniprotkb/F1MD74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MD74-1", "url": "https://www.uniprot.org/uniprotkb/F1MD74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MR96", "url": "https://www.uniprot.org/uniprotkb/F1MR96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MR96-1", "url": "https://www.uniprot.org/uniprotkb/F1MR96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N161", "url": "https://www.uniprot.org/uniprotkb/F1N161", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N161-1", "url": "https://www.uniprot.org/uniprotkb/F1N161-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2N7", "url": "https://www.uniprot.org/uniprotkb/G3N2N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2N7-1", "url": "https://www.uniprot.org/uniprotkb/G3N2N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQPGPKPAASPRPRRAARHTQEHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAIPGSKQLEGPHSPNKKRHKKQAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 799, "header": "tr|G3N2N7-1|G3N2N7_BOVIN Isoform 1 of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=4 CANONICAL=G3N2N7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LI46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI46/entry", "sequence": { "sequence": "MAFASWWYKTCKASACQCRRLRRCGFSPWVGKIPWRRKWQPTPVFLPEESHGERSLVGYRPRGHKESDATERHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAIPGSKQLEGPHSPNKKRHKKQAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 848, "header": "tr|A0A3Q1LI46-1|A0A3Q1LI46_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=3 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96035706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071010.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071010.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058598.3", "url": "https://www.ensembl.org/id/ENSBTAP00000058598.3" } ] } }, { "isoform_ac": "A0A3Q1LLB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLB2/entry", "sequence": { "sequence": "MVLSTGGSPVPTPADSEEVTTSSASASKSSSMNPTEAKAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 704, "header": "tr|A0A3Q1LLB2-1|A0A3Q1LLB2_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=2 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96098489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079894.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079894.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057302.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057302.2" } ] } }, { "isoform_ac": "A0A3Q1LT32-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT32/entry", "sequence": { "sequence": "MAFASWWYKTCKASACQCRRLRRCGFSPWVGKIPWRRKWQPTPVFLPEESHGERSLVGYRPRGHKESDATERHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAIPGSKQLEGPHSPNKKRHKKQAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 835, "header": "tr|A0A3Q1LT32-1|A0A3Q1LT32_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=3 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96035706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076275.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076275.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058259.3", "url": "https://www.ensembl.org/id/ENSBTAP00000058259.3" } ] } }, { "isoform_ac": "A0A3Q1M6S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6S3/entry", "sequence": { "sequence": "MSQPGPKPAASPRPRRAARHTQEVTTSSASASKSSSMNPTEAKAVKTEPEKKPQSSKPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTARDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 712, "header": "tr|A0A3Q1M6S3-1|G3N2N7_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=2 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96034720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087389.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087389.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065716.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065716.2" } ] } }, { "isoform_ac": "A0A3Q1MZC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC5/entry", "sequence": { "sequence": "MSQPGPKPAASPRPRRAARHTQEHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 749, "header": "tr|A0A3Q1MZC5-1|G3N2N7_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=3 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96034720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067827.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067827.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061529.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061529.3" } ] } }, { "isoform_ac": "A0AAA9STT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STT2/entry", "sequence": { "sequence": "MVLSTGGSPVPTPADSEEASFPHYIIGRLQRQVTTSSASASKSSSMNPTEAKAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 741, "header": "tr|A0AAA9STT2-1|G3N2N7_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=1 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96098489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110447.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110447.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086507.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086507.1" } ] } }, { "isoform_ac": "F1MD74-1", "url": "https://www.uniprot.org/uniprotkb/F1MD74/entry", "sequence": { "sequence": "MSQPGPKPAASPRPRRAARHTQEHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAIPGSKQLEGPHSPNKKRHKKQAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 783, "header": "tr|F1MD74-1|F1MD74_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=5 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96034720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027864.8", "url": "https://www.ensembl.org/id/ENSBTAT00000027864.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027864.8", "url": "https://www.ensembl.org/id/ENSBTAP00000027864.8" } ] } }, { "isoform_ac": "F1MR96-1", "url": "https://www.uniprot.org/uniprotkb/F1MR96/entry", "sequence": { "sequence": "MSQPGPKPAASPRPRRAARHTQEHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAIPGSKQLEGPHSPNKKRHKKQVMWFIVPGNTYPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATVRCSPRCVPAARCSCPCPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 797, "header": "tr|F1MR96-1|F1MR96_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=5 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96034720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037077.7", "url": "https://www.ensembl.org/id/ENSBTAT00000037077.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036917.7", "url": "https://www.ensembl.org/id/ENSBTAP00000036917.7" } ] } }, { "isoform_ac": "F1N161-1", "url": "https://www.uniprot.org/uniprotkb/F1N161/entry", "sequence": { "sequence": "MAFASWWYKTHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAIPGSKQLEGPHSPNKKRHKKQAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 786, "header": "tr|F1N161-1|G3N2N7_BOVIN Computationally mapped isoform of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=2 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96035706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011029.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011029.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011029.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011029.5" } ] } }, { "isoform_ac": "G3N2N7-1", "url": "https://www.uniprot.org/uniprotkb/G3N2N7/entry", "sequence": { "sequence": "MSQPGPKPAASPRPRRAARHTQEHVSRKTSGSPSKSGEKKGSDEKKATSLGSSQLSRTQADEKALVPKVTTSSASASKSSSMNPTEAKAIPGSKQLEGPHSPNKKRHKKQAVKTEPEKKPQSSKPSVVHEKKTQEVKPKEHTEPKSLPKHSSDTGSKHAPKEKAVSKSSEQPPSEKSTKPKTKSQDKISGGGKSTVPAAAAAASAEPADKNKENKLLTSAVPAESKPSKPSGKSDMDTALDDLIDTLGEPEEMKEDNTTYTGPEVSDPMSSTYIEELGKRESTLPPKYKELLNKEEGIAGPPPDSLKPLGPNDAIDALSSDFTCSSPTADAKKTEKEKSTEEALKAQSAGVIRSAAPPQEKKRKVEKDAMTEHALEALSASLGTRKPEPELDPSSIKEVDEAKAKEEKVKKCGEDEETVPSEYRLKPATDKDGKPLLPEAEEKPKPLSESELIDELSEDFDQSKCKEKQSKPTEKTEASPAAAPVPVAEDVPRTSMCSVQSAPPTAAPVKGMVPDDAVEALAGSLGKKEADPEDGKPVEDKVKEKAKEEDREKLGEKEETIPPDYRLEEAKDKDGKPLLPKEVKEPLPPLSEDVLLDALSKDFTVPSDTSSPQFEDAKLSAVVSEVVSQTPAPTTQAAGPPPSTAQRDNKELDDALDQLSDSLGQRQPDPDENKPVEDKVKEKAKAEHRDKLGERDDTIPPKYQHLLDDNKEGTPGKPKASEKPKASEKPAGAQDPIDALSGDFDSCPSTTETSTDTPKDKDKKPASSAEAPRNGGKAKDSTKAKEETSKPKADGKSTS", "length": 799, "header": "tr|G3N2N7-1|G3N2N7_BOVIN Isoform 1 of Calpastatin OS=Bos taurus OX=9913 GN=CAST PE=1 SV=4 CANONICAL=G3N2N7-1" }, "locus": { "chromosome": "7", "start_pos": 96164194, "end_pos": 96034720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065978.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065978.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056154.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056154.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Short commuunication: Effect of dietary protein depletion and repletion on skeletal muscle calpastatin during early lactation.", "journal": "Journal of dairy science", "date": "2004-05", "authors": "Cummins K A, Lonergan S M, Huff-Lonergan E", "evidence": [ { "database": "RefSeq", "id": "NP_001025489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025489" } ], "reference": [ { "type": "PubMed", "id": "15290990", "url": "https://glygen.org/publication/PubMed/15290990" } ] }, { "title": "Role of calpastatin in the regulation of mRNA expression of calpain, caspase, and heat shock protein systems in bovine muscle satellite cells.", "journal": "In vitro cellular & developmental biology. Animal", "date": "2015-05", "authors": "Ba Hoa Van, Reddy Bandugula Venkata, Hwang Inho", "evidence": [ { "database": "RefSeq", "id": "NP_001025489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025489" } ], "reference": [ { "type": "PubMed", "id": "25487673", "url": "https://glygen.org/publication/PubMed/25487673" } ] }, { "title": "Association of single nucleotide polymorphisms in CAPN1, CAST and MB genes with meat color of Brahman and crossbreed cattle.", "journal": "Meat science", "date": "2016-07", "authors": "Castro Susan, R\u00edos Marcela, Ortiz Yurany, Manrique Carlos, Jim\u00e9nez Ariel, Ariza Fernando", "evidence": [ { "database": "RefSeq", "id": "NP_001025489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025489" } ], "reference": [ { "type": "PubMed", "id": "26946475", "url": "https://glygen.org/publication/PubMed/26946475" } ] }, { "title": "Effect of the g.98535683A>G SNP in the CAST gene on meat traits of Nellore beef cattle (Bos indicus) and their crosses with Bos taurus.", "journal": "Meat science", "date": "2017-01", "authors": "Enriquez-Valencia Cruz Elena, Pereira Guilherme Luis, Malheiros Jessica Moraes, de Vasconcelos Silva Josineudson Augusto I I, Albuquerque L\u00facia Galv\u00e3o, de Oliveira Henrique Nunes, Chardulo Luis Artur Loyola, Curi Rog\u00e9rio Abdallah", "evidence": [ { "database": "RefSeq", "id": "NP_001025489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025489" } ], "reference": [ { "type": "PubMed", "id": "27636331", "url": "https://glygen.org/publication/PubMed/27636331" } ] }, { "title": "\u03bc-Calpain (CAPN1), calpastatin (CAST), and growth hormone receptor (GHR) genetic effects on Angus beef heifer performance traits and reproduction.", "journal": "Theriogenology", "date": "2018-06", "authors": "Tait Richard G, Cushman Robert A, McNeel Anthony K, Casas Eduardo, Smith Timothy P L, Freetly Harvey C, Bennett Gary L", "evidence": [ { "database": "RefSeq", "id": "NP_001025489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025489" } ], "reference": [ { "type": "PubMed", "id": "29448132", "url": "https://glygen.org/publication/PubMed/29448132" } ] }, { "title": "Association between polymorphisms of Myf5, MSTN and CAST genes and fattening performance in Brown Swiss and Holstein cattle breeds.", "journal": "Animal biotechnology", "date": "2021-02", "authors": "Fadhil Marwan, Z\u00fclkadir U\u011fur", "evidence": [ { "database": "RefSeq", "id": "NP_001025489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025489" } ], "reference": [ { "type": "PubMed", "id": "32564663", "url": "https://glygen.org/publication/PubMed/32564663" } ] } ], "pathway": [ { "id": "bta:281039", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281039", "resource": "KEGG Pathway" }, { "id": "R-BTA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RPY3-1", "uniprot_ac": "F6RPY3", "uniprot_id": "F6RPY3_BOVIN", "mass": { "chemical_mass": 56303.0, "monoisotopic_mass": 56303.0 }, "refseq": {}, "gene_names": [ { "name": "SLC52A2", "type": "recommended", "evidence": [ { "id": "F6RPY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPY3" } ] } ], "protein_names": [ { "name": "Riboflavin transporter", "type": "recommended", "evidence": [ { "id": "F6RPY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPY3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1N6I5", "url": 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"https://alphafold.ebi.ac.uk/entry/F6RPY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000857", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12929", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12929", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12929:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12929:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196843", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "35015", "url": "https://www.rhea-db.org/rhea/35015", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1N6I5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXY2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFF4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFF4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPY3", "url": "https://www.uniprot.org/uniprotkb/F6RPY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPY3-1", "url": "https://www.uniprot.org/uniprotkb/F6RPY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKNLPEGWSLPSYLCVLVALGNLGLLVVTMWKRLAPGKGERVPIQVVQALSVVGTALLAPLWPQVTTVAGQEHSVAFLALAFVLALACCASNVTFLPFLSRLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPTPTNGTPGPPLYFPERFPASTFFGILSTLLVISAAAFQGLLLLLPLPPSVPTGGPGPGLRVGTLGAEKEEEEEASPLQEPPSPAADATPSPEPVGPRLLSTHGAFLLGLLAVTNALTNGVLPAVQSYSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLGGLSLLGMFFGAYLMALAVLSPCPPLVGTSAGVVLVPATMFTLPGGVVDSVSGRVLVREGGCQLAPAWWGPAGVAGRWRGHPGGLPARRRGHVPSHQHLPSVPQREGLRGPLWPLSLVLGGTLLPPPVFRVPQRLPVHCLERPTSHAACSRTVAHSTGEPGTAGRWRTQQAQSHGPSGDMDLAQDLCGICTIKHFYSVSW", "length": 540, "header": "tr|F6RPY3-1|F6RPY3_BOVIN Isoform 1 of Riboflavin transporter OS=Bos taurus OX=9913 GN=SLC52A2 PE=3 SV=1 CANONICAL=F6RPY3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6I5/entry", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKNLPEGWSLPSYLCVLVALGNLGLLVVTMWKRLAPGKGERVPIQVVQALSVVGTALLAPLWPQVTTVAGQEHSVAFLALAFVLALACCASNVTFLPFLSRLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPTPTNGTPGPPLYFPERFPASTFFGILSTLLVISAAAFQGLLLLLPLPPSVPTGGPGPGLRVGTLGAEKEEEEEASPLQEPPSPAADATPSPEPVGPRLLSTHGAFLLGLLAVTNALTNGVLPAVQSYSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLGGLSLLGMFFGAYLMALAVLSPCPPLVGTSAGVVLVVVSWILCLGVFSYVKVAASSLLHGGGQPALLAAGVAIQGATETACPLPGEAHLTCGLLTDSCTLHRRTWHCRQVEDTAGSEPWPIWRHGLGPGFVWDLYNKAFLFR", "length": 482, "header": "tr|A0A3Q1N6I5-1|F6RPY3_BOVIN Computationally mapped isoform of Riboflavin transporter OS=Bos taurus OX=9913 GN=SLC52A2 PE=3 SV=2 CANONICAL=F6RPY3-1" }, "locus": { "chromosome": "14", "start_pos": 580063, "end_pos": 578179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083852.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083852.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066100.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066100.2" } ] } }, { "isoform_ac": "A0AAA9RXY2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXY2/entry", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKNLPEGWSLPSYLCVLVALGNLGLLVVTMWKRLAPGKGERVPIQVVQALSVVGTALLAPLWPQVTTVAGQEHSVAFLALAFVLALACCASNVTFLPFLSRLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPTPTNGTPGPPLYFPERFPASTFFGILSTLLVISAAAFQGLLLLLPLPPSVPTGGPGPGLRVGTLGAEKEEEEEASPLQEPPSPAADATPSPEPVGPRLLSTHGAFLLGLLAVTNALTNGVLPAVQSYSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRWCRGFCVWACSRT", "length": 348, "header": "tr|A0AAA9RXY2-1|F6RPY3_BOVIN Computationally mapped isoform of Riboflavin transporter OS=Bos taurus OX=9913 GN=SLC52A2 PE=3 SV=1 CANONICAL=F6RPY3-1" }, "locus": { "chromosome": "14", "start_pos": 580063, "end_pos": 578599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112640.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112640.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078399.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078399.1" } ] } }, { "isoform_ac": "A0AAA9TFF4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFF4/entry", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKNLPEGGVVDSVSGRVLVREGGCQLAPAWWGPAGVAGRWRGHPGGLPARRRGHVPSHQHLPSVPQREGLRGPLWPLSLVLGGTLLPPPVFRVPQRLPVHCLERPTSHAACSRTVAHSTGEPGTAGRWRTQQAQSHGPSGDMDLAQDLCGICTIKHFYSVSWSQSQEQLLRCR", "length": 210, "header": "tr|A0AAA9TFF4-1|F6RPY3_BOVIN Computationally mapped isoform of Riboflavin transporter OS=Bos taurus OX=9913 GN=SLC52A2 PE=3 SV=1 CANONICAL=F6RPY3-1" }, "locus": { "chromosome": "14", "start_pos": 580063, "end_pos": 578139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112803.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112803.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095734.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095734.1" } ] } }, { "isoform_ac": "F6RPY3-1", "url": "https://www.uniprot.org/uniprotkb/F6RPY3/entry", "sequence": { "sequence": "MAAPPLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKNLPEGWSLPSYLCVLVALGNLGLLVVTMWKRLAPGKGERVPIQVVQALSVVGTALLAPLWPQVTTVAGQEHSVAFLALAFVLALACCASNVTFLPFLSRLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPTPTNGTPGPPLYFPERFPASTFFGILSTLLVISAAAFQGLLLLLPLPPSVPTGGPGPGLRVGTLGAEKEEEEEASPLQEPPSPAADATPSPEPVGPRLLSTHGAFLLGLLAVTNALTNGVLPAVQSYSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLGGLSLLGMFFGAYLMALAVLSPCPPLVGTSAGVVLVPATMFTLPGGVVDSVSGRVLVREGGCQLAPAWWGPAGVAGRWRGHPGGLPARRRGHVPSHQHLPSVPQREGLRGPLWPLSLVLGGTLLPPPVFRVPQRLPVHCLERPTSHAACSRTVAHSTGEPGTAGRWRTQQAQSHGPSGDMDLAQDLCGICTIKHFYSVSW", "length": 540, "header": "tr|F6RPY3-1|F6RPY3_BOVIN Isoform 1 of Riboflavin transporter OS=Bos taurus OX=9913 GN=SLC52A2 PE=3 SV=1 CANONICAL=F6RPY3-1" }, "locus": { "chromosome": "14", "start_pos": 580063, "end_pos": 578172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001142.5", "url": "https://www.ensembl.org/id/ENSBTAT00000001142.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001142.4", "url": "https://www.ensembl.org/id/ENSBTAP00000001142.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 175, "start_aa": "Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 180, "start_aa": "Thr", "end_pos": 180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr180", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 262, "start_aa": "Thr", "end_pos": 262, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr262", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-196843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196843", "resource": "Reactome", "description": "Vitamin B2 (riboflavin) metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RPY3", "url": "https://www.uniprot.org/uniprotkb/F6RPY3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "riboflavin transmembrane transporter activity", "id": "GO:0032217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032217", "evidence": [ { "database": "UniProtKB", "id": "F6RPY3", "url": "https://www.uniprot.org/uniprotkb/F6RPY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "riboflavin transport", "id": "GO:0032218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032218", "evidence": [ { "database": "UniProtKB", "id": "F6RPY3", "url": "https://www.uniprot.org/uniprotkb/F6RPY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "35015", "name": "", "equation": "riboflavin(in) = riboflavin(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "35015", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35015" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 175, 180, 262 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 178, "end_pos": 180 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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"F6RWU6_BOVIN", "mass": { "chemical_mass": 38346.0, "monoisotopic_mass": 38346.0 }, "refseq": { "ac": "XP_005214576", "name": "acyl-coenzyme A thioesterase 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214576" }, "gene_names": [ { "name": "ACOT8", "type": "recommended", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "name": "ACOT8", "type": "synonym", "evidence": [ { "id": "XP_005214576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214576" } ] } ], "protein_names": [ { "name": "Acyl-coenzyme A thioesterase 8", "type": "recommended", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.11", "type": "synonym", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6/entry#names_and_taxonomy" } ] }, { "name": 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Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains. Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). Is also able to hydrolyze CoA esters of dicarboxylic acids. 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"id": "14541", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14541" } ] }, { "id": "15673", "name": "", "equation": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "15673", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15673" } ] }, { "id": "16305", "name": "", "equation": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "16305", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16305" } ] }, { "id": "16645", "name": "", "equation": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "P45478-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "Q1JQA0-1", "A0AAA9T509-1", "E1BB89-1", "A0AAA9SCF5-1" ], "evidence": [ { "id": "16645", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16645" } ] }, { "id": "20289", "name": "", "equation": "acetyl-CoA + H2O = acetate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0R7-1", "E1BNW7-1", "F6RWU6-1" ], "evidence": [ { "id": "20289", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20289" } ] }, { "id": "30135", "name": "", "equation": "dodecanoyl-CoA + H2O = dodecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "30135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30135" } ] }, { "id": "30139", "name": "", "equation": "octadecanoyl-CoA + H2O = octadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJT0-1", "F6RWU6-1" ], "evidence": [ { "id": "30139", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30139" } ] }, { "id": "30143", "name": "", "equation": "octanoyl-CoA + H2O = octanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "30143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30143" } ] }, { "id": "31511", "name": "", "equation": "chenodeoxycholoyl-CoA + H2O = chenodeoxycholate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "31511", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/31511" } ] }, { "id": "40059", "name": "", "equation": "decanoyl-CoA + H2O = decanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "40059", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40059" } ] }, { "id": "40103", "name": "", "equation": "propanoyl-CoA + H2O = propanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0R7-1", "Q3SWX2-1", "F6RWU6-1" ], "evidence": [ { "id": "40103", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40103" } ] }, { "id": "40111", "name": "", "equation": "butanoyl-CoA + H2O = butanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M171-1", "E1BNW7-1", "Q3T0R7-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40111", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40111" } ] }, { "id": "40115", "name": "", "equation": "hexanoyl-CoA + H2O = hexanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0R7-1", "E1BNW7-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40115", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40115" } ] }, { "id": "40119", "name": "", "equation": "tetradecanoyl-CoA + H2O = tetradecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "40119", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40119" } ] }, { "id": "40131", "name": "", "equation": "(9Z)-hexadecenoyl-CoA + H2O = (9Z)-hexadecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40131", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40131" } ] }, { "id": "40135", "name": "", "equation": "(9Z)-tetradecenoyl-CoA + H2O = (9Z)-tetradecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40135" } ] }, { "id": "40139", "name": "", "equation": "(9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A0ABI0P2S3-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40139", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40139" } ] }, { "id": "40143", "name": "", "equation": "(9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40143" } ] }, { "id": "40147", "name": "", "equation": "eicosanoyl-CoA + H2O = eicosanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40147", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40147" } ] }, { "id": "40151", "name": "", "equation": "(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A0ABI0P2S3-1", "F6RWU6-1" ], "evidence": [ { "id": "40151", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40151" } ] }, { "id": "40219", "name": "", "equation": "malonyl-CoA + H2O = malonate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40219", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40219" } ] }, { "id": "40223", "name": "", "equation": "4,8-dimethylnonanoyl-CoA + H2O = 4,8-dimethylnonanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SWX2-1", "F6RWU6-1" ], "evidence": [ { "id": "40223", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40223" } ] }, { "id": "40575", "name": "", "equation": "glutaryl-CoA + H2O = glutarate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40575", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40575" } ] }, { "id": "40583", "name": "", "equation": "hexanedioyl-CoA + H2O = hexanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40583", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40583" } ] }, { "id": "40587", "name": "", "equation": "octanedioyl-CoA + H2O = octanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40587", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40587" } ] }, { "id": "40591", "name": "", "equation": "decanedioyl-CoA + H2O = decanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40591", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40591" } ] }, { "id": "40595", "name": "", "equation": "dodecanedioyl-CoA + H2O = dodecanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "40595", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40595" } ] }, { "id": "59936", "name": "", "equation": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "59936", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59936" } ] }, { "id": "59940", "name": "", "equation": "2-methyloctadecanoyl-CoA + H2O = 2-methyloctadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "59940", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59940" } ] }, { "id": "59948", "name": "", "equation": "prostaglandin F2alpha-CoA + H2O = prostaglandin F2alpha + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "59948", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59948" } ] }, { "id": "59952", "name": "", "equation": "2,6-dimethylheptanoyl-CoA + H2O = 2,6-dimethylheptanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "59952", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59952" } ] }, { "id": "R-BTA-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-192356" ], "output_participant_list": [ "R-ALL-193451" ], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "R-BTA-193385", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193385" } ] }, { "id": "R-BTA-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-2066765" ], "output_participant_list": [ "R-ALL-2066763" ], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "R-BTA-2066779", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2066779" } ] }, { "id": "R-BTA-390304", "name": "acetyl-CoA + H2O => acetate + CoASH + H+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-353123" ], "output_participant_list": [ "R-ALL-390305" ], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "R-BTA-390304", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390304" } ] }, { "id": "R-BTA-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWU6-1" ], "evidence": [ { "id": "R-BTA-5690042", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690042" } ] }, { "id": "R-BTA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033235" } ] }, { "id": "R-BTA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-192356", "participant_name": "choloyl-CoA [peroxisomal matrix]", "crossref": [ { "id": "57373", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-193451", "participant_name": "CCA [peroxisomal matrix]", "crossref": [ { "id": "29747", "database": "ChEBI", "url": "" }, { "id": "ZINC000006858022", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2066763", "participant_name": "DHA [peroxisomal matrix]", "crossref": [ { "id": "ZINC000004474564", "database": "ZINC", "url": "" }, { "id": "77016", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2066765", "participant_name": "DHA-CoA [peroxisomal matrix]", "crossref": [ { "id": "65132", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-353123", "participant_name": "Ac-CoA [peroxisomal matrix]", "crossref": [ { "id": "57288", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551095", "database": "ZINC", "url": "" }, { "id": "C00024", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-390305", "participant_name": "CH3COO- [peroxisomal matrix]", "crossref": [ { "id": "C00033", "database": "COMPOUND", "url": "" }, { "id": "30089", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8A5", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] } ] }, { "uniprot_ac": "A0A3Q1LQH8", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LS67", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] } ] }, { "uniprot_ac": "A0A3Q1LTU2", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LYY4", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] } ] }, { "uniprot_ac": "A0A3Q1M171", "gene_name": "ACOT11", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] } ] }, { "uniprot_ac": "A0AAA9SAI8", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0AAA9SAI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAI8" } ] } ] }, { "uniprot_ac": "A0AAA9SC38", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] } ] }, { "uniprot_ac": "A0AAA9SCF5", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] } ] }, { "uniprot_ac": "A0AAA9SND8", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] } ] }, { "uniprot_ac": "A0AAA9SXG3", "gene_name": "DAO", "activity": [ { "ec_number": "1.4.3.3", "activity": "D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + H2O2 + NH4(+).", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] }, { "ec_number": "1.4.3.3", "activity": "", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] } ] }, { "uniprot_ac": "A0AAA9T509", "gene_name": "OLAH", "activity": [ { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "A0AAA9T509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T509" } ] }, { "ec_number": "3.1.2.14", "activity": "", "evidence": [ { "id": "A0AAA9T509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T509" } ] } ] }, { "uniprot_ac": "A0AAA9TBR3", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] } ] }, { "uniprot_ac": "A0AAA9TW47", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] } ] }, { "uniprot_ac": "A0AAA9TYP4", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] } ] }, { "uniprot_ac": "A0AAA9TZC7", "gene_name": "ECI2", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] } ] }, { "uniprot_ac": "A0ABI0P2S3", "gene_name": "THEM4", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0ABI0P2S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0ABI0P2S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ] } ] }, { "uniprot_ac": "A1A4L1", "gene_name": "THEM4", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A1A4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4L1" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A1A4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4L1" } ] } ] }, { "uniprot_ac": "A5PJT0", "gene_name": "MBLAC2", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJT0" } ] }, { "ec_number": "3.5.2.6", "activity": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJT0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJT0" } ] } ] }, { "uniprot_ac": "E1BB89", "gene_name": "PLA2G6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] } ] }, { "uniprot_ac": "E1BNW7", "gene_name": "ACOT12", "activity": [ { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ] } ] }, { "uniprot_ac": "F1MQP2", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] } ] }, { "uniprot_ac": "F1MV74", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] } ] }, { "uniprot_ac": "F1MVP8", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] } ] }, { "uniprot_ac": "F1MYR5", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] } ] }, { "uniprot_ac": "F6QGE6", "gene_name": "ACOT13", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6QGE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6QGE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ] } ] }, { "uniprot_ac": "F6RWU6", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] } ] }, { "uniprot_ac": "O19094", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] } ] }, { "uniprot_ac": "P00432", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N7I7", "url": "https://www.orthodb.org/?gene=A0A3Q1N7I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N0S6", "url": "https://www.orthodb.org/?gene=G3N0S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10336:SF166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10336:SF166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09279", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09279", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "33179", "url": "https://www.rhea-db.org/rhea/33179", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1N7I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0S6-1", "url": "https://www.uniprot.org/uniprotkb/G3N0S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPSPEDPGPDLESRRSFLSTNIVPVVERCMSAMQAGTQMVKLRGSSKGLVRFYFLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEIFQRYPDGSFDPNCCFSIYHGSHRESLDLVSPSGDEARTWVTGLRYLMAGISDEDSLARRQRTRDQYPRQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFKEADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDATDLLRFLEVEQKMTGVTLESCRDIIEQFEPCPENKSKGAMGIDGFTNYTRSPAGDIFNPEHRLVHQDMTQPLSHYFITSSHNTYLAGDQLTSQSRADMYARVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATMLPSPQVLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDEDCKLLNGDASTNRKRVENIAKRKLDSLMKESKIRDCEDPSDFTVSTLPPPGKLGPKAEAKKFEEDVEIGEEAGTSRRNSRLLMGSFSKRKKKSSKLKKAASVEEGDEDLDSQGSQSRGAARQKKTMKLSRALSDLVKYTKSVGTHDVETEVASSWQVSSFSETKAQQILQQKPAQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGSCGYVLKPQCMCQGIFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEVIGLPVDCNKEQTRVVDDNGFNPMWEETLVFTVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPLPRPSVSQRLLRRTASAPTKSQKPGRKAFPELVLGLQDTGSEGEAGDVAPSSPGPIPEAPTREEPGSRSPREPRPFSMQRSVSSLCSLETIAEEPALGPGPLLPGATPPSHAPGGPQCSTGLSTLSASPPRVAVEAPRPLQLQTGSHASAEPAPGSRQWACSTGGPAGACKGAPSGHIEGKGHPRALGHVPRRAKSEGQVPSESLGGRWPLAGPCPTVSLDATGGDRLWQRLEPGSHRGSVSSSSSLSSSDTVIELALPGLGLGLGCDSLPGTLAGRLPLRPCSAPVACLDPPAVTKSKSNPNLRAAGQLPVGPDRLQPLPLAPGPPWRRLPLAGLPDCTVAAKSKSLGDLTADDFAPRVESLGRGLGLAGERPAGRRVRPDALTEQLRWLTGFQQAGDITSPTSLGPTGEGVAGAPGFLRRSSSRSQSRVRAIASRARQAQERQQRLRGPRGPPEEERGTPEGACSVGQEGCGDVQAPSKGATHQPLGAAATGLLLRF", "length": 1402, "header": "tr|G3N0S6-1|G3N0S6_BOVIN Isoform 1 of Phosphoinositide phospholipase C OS=Bos taurus OX=9913 GN=PLCH2 PE=4 SV=3 CANONICAL=G3N0S6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N7I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7I7/entry", "sequence": { "sequence": "MEAPGDPGGLSLDQVERCMSAMQAGTQMVKLRGSSKGLVRFYFLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEIFQRYPDGSFDPNCCFSIYHGSHRESLDLVSPSGDEARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFKEADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDATDLLRFLEVEQKMTGVTLESCRDIIEQFEPCPENKSKGAMGIDGFTNYTRSPAGDIFNPEHRLVHQDMTQPLSHYFITSSHNTYLAGDQLTSQSRADMYARVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATMLPSPQVLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDEDCKLLNGDASTNRKRVENIAKRKLDSLMKESKIRDCEDPSDFTVSTLPPPGKLGPKQFEEDVEIGEEAGTSRRNSRLLMGSFSKRKKKSSKLKKAASVEEGDEDLDSQGSQSRGAARQKKTMKLSRALSDLVKYTKSVGTHDVETEVASSWQVSSFSETKAQQILQQKPAQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGSCGYVLKPQCMCQGIFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEVIGLPVDCNKEQTRVVDDNGFNPMWEETLVFTVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPLPRPSVSQRLLRRTASAPTKSQKPGRKAFPELVLGLQDTGSEGEAGDVAPSSPGPIPEAPTREEPGSRSPRGKAPAERSPEQEQPPRVPVGPGPAGMAATCMKCVVGSCAGEDAEGLHRGRLPSPGPEGGHSAISQQPRAWEDSLGAPHAAPGRSRGAPKGSRARHPGPGGSGSMSSDSSSPGSPEGATRWPEGTRRQAGALQREMNALFIQKLEEIRSKSPVFSTVRN", "length": 1116, "header": "tr|A0A3Q1N7I7-1|G3N0S6_BOVIN Computationally mapped isoform of Phosphoinositide phospholipase C OS=Bos taurus OX=9913 GN=PLCH2 PE=4 SV=2 CANONICAL=G3N0S6-1" }, "locus": { "chromosome": "16", "start_pos": 50394804, "end_pos": 50362896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076801.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076801.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066685.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066685.2" } ] } }, { "isoform_ac": "G3N0S6-1", "url": "https://www.uniprot.org/uniprotkb/G3N0S6/entry", "sequence": { "sequence": "MAPSPEDPGPDLESRRSFLSTNIVPVVERCMSAMQAGTQMVKLRGSSKGLVRFYFLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEIFQRYPDGSFDPNCCFSIYHGSHRESLDLVSPSGDEARTWVTGLRYLMAGISDEDSLARRQRTRDQYPRQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFKEADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDATDLLRFLEVEQKMTGVTLESCRDIIEQFEPCPENKSKGAMGIDGFTNYTRSPAGDIFNPEHRLVHQDMTQPLSHYFITSSHNTYLAGDQLTSQSRADMYARVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATMLPSPQVLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDEDCKLLNGDASTNRKRVENIAKRKLDSLMKESKIRDCEDPSDFTVSTLPPPGKLGPKAEAKKFEEDVEIGEEAGTSRRNSRLLMGSFSKRKKKSSKLKKAASVEEGDEDLDSQGSQSRGAARQKKTMKLSRALSDLVKYTKSVGTHDVETEVASSWQVSSFSETKAQQILQQKPAQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGSCGYVLKPQCMCQGIFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEVIGLPVDCNKEQTRVVDDNGFNPMWEETLVFTVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPLPRPSVSQRLLRRTASAPTKSQKPGRKAFPELVLGLQDTGSEGEAGDVAPSSPGPIPEAPTREEPGSRSPREPRPFSMQRSVSSLCSLETIAEEPALGPGPLLPGATPPSHAPGGPQCSTGLSTLSASPPRVAVEAPRPLQLQTGSHASAEPAPGSRQWACSTGGPAGACKGAPSGHIEGKGHPRALGHVPRRAKSEGQVPSESLGGRWPLAGPCPTVSLDATGGDRLWQRLEPGSHRGSVSSSSSLSSSDTVIELALPGLGLGLGCDSLPGTLAGRLPLRPCSAPVACLDPPAVTKSKSNPNLRAAGQLPVGPDRLQPLPLAPGPPWRRLPLAGLPDCTVAAKSKSLGDLTADDFAPRVESLGRGLGLAGERPAGRRVRPDALTEQLRWLTGFQQAGDITSPTSLGPTGEGVAGAPGFLRRSSSRSQSRVRAIASRARQAQERQQRLRGPRGPPEEERGTPEGACSVGQEGCGDVQAPSKGATHQPLGAAATGLLLRF", "length": 1402, "header": "tr|G3N0S6-1|G3N0S6_BOVIN Isoform 1 of Phosphoinositide phospholipase C OS=Bos taurus OX=9913 GN=PLCH2 PE=4 SV=3 CANONICAL=G3N0S6-1" }, "locus": { "chromosome": "16", "start_pos": 50424600, "end_pos": 50361365, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063344.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063344.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055444.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055444.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1010, "start_aa": "Thr", "end_pos": 1010, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1010", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1120, "start_aa": "Thr", "end_pos": 1120, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1120", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "G3N0S6", "url": "https://www.uniprot.org/uniprotkb/G3N0S6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "33179", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SDK5-1", "A0AAA9S613-1", "G3N0S6-1", "F1MF11-1", "E1BH60-1", "A0A3Q1NG43-1", "P10895-1", "A0AAF6YYJ2-1", "P10894-1", "P21671-1", "P08487-1", "Q07722-1", "Q1RML2-1", "A7MB47-1", "F1MSD7-1", "E1B7M6-1", "A0A3Q1MTC3-1", "A0AAA9SMQ6-1" ], "evidence": [ { "id": "33179", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33179" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MTC3", "gene_name": "PLCL1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A3Q1MTC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTC3" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A3Q1MTC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTC3" } ] } ] }, { "uniprot_ac": "A0A3Q1NG43", "gene_name": "PLCE1", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A3Q1NG43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG43" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "A0A3Q1NG43", "database": "UniProtKB", 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"G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MED14", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3", "locus": { "chromosome": "X", "start_pos": 102843175, "end_pos": 102781425, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011790", "url": "https://www.ensembl.org/id/ENSBTAG00000011790" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011790", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011790", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "529109", "url": "https://www.ncbi.nlm.nih.gov/gene/529109", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529109", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529109", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KQPAYFI", "url": "https://omabrowser.org/oma/group/KQPAYFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N7M9", "url": "https://www.orthodb.org/?gene=A0A3Q1N7M9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X6Y3", "url": "https://www.orthodb.org/?gene=G3X6Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12809:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12809:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22983", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22983", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25065", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25065", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193960", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7M9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N7M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQC7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEF0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6Y3-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPVQLENHQLVPPGGSGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDASKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGVNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITSETLQLSNYSTHPIGNLSKNKLFVRLTRLPQYYIVVEMLEVPNKPTQLSYKYYFLSVNAVDRDDSPLMALLLQQFKENLQESVYRTKNGKQPRTSTKRKLSDDLCPVEPKKTKRSGEMRAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGINEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPSHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1452, "header": "tr|G3X6Y3-1|G3X6Y3_BOVIN Isoform 1 of Mediator of RNA polymerase II transcription subunit 14 OS=Bos taurus OX=9913 GN=MED14 PE=3 SV=2 CANONICAL=G3X6Y3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N7M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7M9/entry", "sequence": { "sequence": "MAPVQLENHQLVPPGGSGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDASKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGVNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITSETLQLSNYSTHPIGNLSKNKLFVRLTRLPQYYIVVEMLEVPNKPTQLSYKYYFLSVNAVDRDDSPLMALLLQQFKENLQESVYRTKNGKQPRTSTKRKLSDDLCPVEPKKTKRSGEMRAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGINEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPSHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1408, "header": "tr|A0A3Q1N7M9-1|G3X6Y3_BOVIN Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 14 OS=Bos taurus OX=9913 GN=MED14 PE=3 SV=1 CANONICAL=G3X6Y3-1" }, "locus": { "chromosome": "X", "start_pos": 102840934, "end_pos": 102781533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083283.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083283.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066784.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066784.1" } ] } }, { "isoform_ac": "A0AAA9SQC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQC7/entry", "sequence": { "sequence": "MAPVQLENHQLVPPGGSGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDASKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGVNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITSETLQLSNYSTHPIGNLSKNKLFVRLTRLPQYYIVVEMLEVPNKPTQLSYKYYFLSVNAVDRDDSPLMALLLQQFKENLQESVYRTKNGKQPRTSTKRKLSDDLCPVEPKKTKRSGEMRAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGINEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPSHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRFYRCLHFFVKRRGGPWRTQDSQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1443, "header": "tr|A0AAA9SQC7-1|G3X6Y3_BOVIN Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 14 OS=Bos taurus OX=9913 GN=MED14 PE=3 SV=1 CANONICAL=G3X6Y3-1" }, "locus": { "chromosome": "X", "start_pos": 102840934, "end_pos": 102781533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105742.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105742.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085141.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085141.1" } ] } }, { "isoform_ac": "A0AAA9TEF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEF0/entry", "sequence": { "sequence": "MAPVQLENHQLVPPGGSGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDASKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGVNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITSETLQLSNYSTHPIGNLSKNKLFVRLTRLPQYYIVVEMLEVPNKPTQLSYKYYFLSVNAVDRDDSPLMALLLQQFKENLQESVYRTKNGKQPRTSTKRKLSDDLCPVEPKKTKRSGEMRAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGINEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPSHLNIFSEVRVYNYRKLILCYGTTKGSSRDYYNEDYVQMVLNNTISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1468, "header": "tr|A0AAA9TEF0-1|G3X6Y3_BOVIN Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 14 OS=Bos taurus OX=9913 GN=MED14 PE=3 SV=1 CANONICAL=G3X6Y3-1" }, "locus": { "chromosome": "X", "start_pos": 102840934, "end_pos": 102781533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119178.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119178.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094548.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094548.1" } ] } }, { "isoform_ac": "G3X6Y3-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3/entry", "sequence": { "sequence": "MAPVQLENHQLVPPGGSGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDASKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGVNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITSETLQLSNYSTHPIGNLSKNKLFVRLTRLPQYYIVVEMLEVPNKPTQLSYKYYFLSVNAVDRDDSPLMALLLQQFKENLQESVYRTKNGKQPRTSTKRKLSDDLCPVEPKKTKRSGEMRAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGINEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPSHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1452, "header": "tr|G3X6Y3-1|G3X6Y3_BOVIN Isoform 1 of Mediator of RNA polymerase II transcription subunit 14 OS=Bos taurus OX=9913 GN=MED14 PE=3 SV=2 CANONICAL=G3X6Y3-1" }, "locus": { "chromosome": "X", "start_pos": 102840934, "end_pos": 102781533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015654.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015654.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015654.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015654.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1189, "start_aa": "Thr", "end_pos": 1189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1189", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1352, "start_aa": "Thr", "end_pos": 1352, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1352", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:529109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529109", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" }, { "id": "R-BTA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XAD1-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPVQLESNQLVPAGGGPASAPAPPAPGAVTAAASPGYRLSTLIDFLLHRTYAELTVLADLLPRKTDMERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKSEKQTTLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDIPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLALQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDETDVSKPLQISHEPPLPSCDSKLMERAMKIDHLSIEKLLIDSVHARSHQKLQELKAILKSYNVNDNSFIETALPTLVIPILEPCGRSECLHVFVDLHSGMFQLMLYGVDQVTLDDIEKCVNDDMKRIVPWLQQLKFWLGQQRCKQSIKHLPTVSSETLQLANHASHPVGNLSKHKLFIKLTRLPQYYIVVEMFDVPGNPTELEYKYYFLSVSYAEGDDNPATALLLQQFKPNIEELVLDTKSGKQMKSGVKRKLSGDPCSIEPKKPKRTGEMCAFNKVLAHIVAMCDTNMPFIGLRLELSNMDIPHQGVQVEGDGFSHAIRLLKIPPCKGVNEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNSTSSREQGPTRHVYLTYENQLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPNHLNIFSEVRIYNYRKLILCYGTTKGSSISIQWNSILQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVLLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSPTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKIVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPQQPPQQPQQPFAKQAGASGAYPLTSPPTSYHNTVTPSPSMMHTQSPGNLHAASSPSGALRAPSPASFGPTPSPSSLGITMGQTANFASPHGTIDPSSPYTMMSPSQRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPIPDASHSPRAGTSSQAMPTSMPPPRKLPQRSWAASIPTILTHSALNVLLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTEALKCRVALNPKTNQTLQLKVTPENTGQWKSEELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQASQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTAVSQEAVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAELNSPRPGECTIFAAVRDLMLNLTLPPGGRP", "length": 1446 }, "evidence": [ { "id": "G3X6Y3", "url": "https://omabrowser.org/oma/group/G3X6Y3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2ABV5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "Med14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVQLDNHQLIPPGGGGGSSGGGGSSSGSASAPAPPPPAAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANDAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPEVPWRLLKLEILVEDKETGDGRALVHSMQIDFIHQLVQSRLFADEKPLQDMYNCLHCFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKSLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQRLQELKAILRSFNANESSSIETALPALIVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDPATLEDMEKSLNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITTETLQLANYSTHPIGSLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYNYYFMSVSTADREDSPVMALLLQQFKDNIQDLMSYTKTGKQTRTGTKHKLSDDPCPIDSKKAKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFNHAIRLLKIPPCKGISEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWSSIARLYECVLEFARSLPEIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHIALGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRLPGMSPANPSLHSPVPDVSHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1459 }, "evidence": [ { "id": "G3X6Y3", "url": "https://omabrowser.org/oma/group/G3X6Y3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A020-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "Med14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPVQLENHQLIPPGGGGGSGGGGGSSSGSASVPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANDAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPEVPWRLLKLEILVEDKETGDGRALVHSMQIDFIHQLVQSRLFADEKPLQDMYNCLHCFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRSFNANENSSIETALPALIVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLEDMEKSLNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTITTETLQLANYATHPIGSLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVSTADRDDSPAMALLLQQFKDNIQDLMSCTNTGKQTRTGTKHKLSDDSCPVECKKAKRSGETCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGISEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWSSIARLYECVLEFARSLPEIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPQQQPFPKQPGTSGAYPLTSPPASYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGALDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRLPGMSPANPSLHSPVPDVSHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1459 }, "evidence": [ { "id": "G3X6Y3", "url": "https://omabrowser.org/oma/group/G3X6Y3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RX18-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPVQLENHQLVPPGGGGGGSGGPASAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFAGRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKVEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQINFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPVMALLLQQFKENIQELVYRTKNGKQPKTSTKRKLSDDLCPVEPKKTKRSGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQMEGDGFSHAIRLLKIPPCKGVNEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPTHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGSSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPATRMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1454 }, "evidence": [ { "id": "G3X6Y3", "url": "https://omabrowser.org/oma/group/G3X6Y3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60244-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLHRAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISSFLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPPDPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDDPDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFCLSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIKIDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAILRGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEKSVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFIKLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVFRTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLELSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTWVAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECVLEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGPNSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTAYQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVRDLMANLTLPPGGRP", "length": 1454 }, "evidence": [ { "id": "G3X6Y3", "url": "https://omabrowser.org/oma/group/G3X6Y3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0P8-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPTPLPLEQMPGVGGGGGGYLPAAQEGGPRINTMSMSVLIDFIIQRTYHELTVLAELLPRKTDMERKVEIYNYAARTRHLFTRLNALVKWGNSVSKVDKSSQIMSFLDKQNMLFVETADMLARMSRETLVRARLPNFHIPAAVEVLTTGTYNRLPTCIRERIVPADAITPAEKRQTLLRLNQVIQHRLVTGKLLPQMREFRIRNGRVTFEVKHEFSVSLTVMGDNPTVPWRLLDIDVLVEDKETGDGKSLVHPLQVNYIHQLIQARLVENPNALSEVYNCLHYFCQSLQLEVLYTQTLRLNYERLDDNNITVEEYVPGVKLTVSYWRDLKSELGYRLTVQSDPSEIGRPLAVVHVPSLGAKESAEVADRAVRSEHLSMERLIVHTVYIRSVSRLSDLKLEFQAFLKDVDFNLQGTPAILTVPVLSPCLRAEQIHITIDTHTGMFRCHVPKHLDCPIMEEMQDCLNGDRSKLPALLSELRFWITHRRCDKTLQHLPATATETLPFLVQPDQEILQPGRHKIYVKLHRHPNIVLVVQLKEKTTMPNEMEYTFHLGFVAYQKDELDVIDDSAMQLVSIVAQPHSDIPKCYTKLMRLIEFDTFVATHGPGTEVDAEVSPHKRKSNGDLLAPPAKQQKTIFPAYFIPELAHVVAMCDEKIPFMNLAQTLSKHNIPHSGLQVEANATSLVLKILALPQPGKTTFATQQQQQQGAPAVAGENKPSGTSGLPKIDSHVWDDLMRRVLSISIRSQTNKNSQVRIWVVEFVFYSTPLQSSHPKEQGSRRTVYLTYEQANYDFSKTVEDLLNDWSKIVYLYTLVYDFAEQLLNKRLSLCDMLVVKSYSYMNLLLGYGPKKEVSCNIYWSVQSHGFRLTFVGGMSAVNGHSMMRDQLAQHLNQQHSITQIAQILHETYNPLSSIAKLPVLPFLGIPRPQVPVLSFCVLAQSPCLIRLTYQAVYCLELRFRANRLVSIRDGASSRFERNVVEEFTPIQGLKAFLSKYVDESAVYRGRASHEDDNPLSPMGMEDNFGGPSSVAGVSAGGSSPFLGTGMRGPQSPRDSGLRFPAPHTPPSSSNPHTPASPHPSAGAGGGSGPQGHGNFNLTSPPAPHMPHPSPSGLMPSSPLNPQPSPHMVHSPGPNTLYMQSHQDSPFTAMSPANNNWPGSPSMPRPSPRPGQSPDHKSTGGGAGVAGGTDRGGSRGTLNRPWAGAVPTLLTHEALETLCRPSPYPNKDINVPDMSPLERFLGCVYMRRQLHRNIQSEETLTALNSTEPGVVLFKVDGLQCQVVLNQMHMQTLHLKVSQLPPMPDKHPPPFQLSQDDLLVIEQYFDTRVAAPPYRPNSLHSICRLLNLPAQVLKDFVQIMRLDLKPELGGDQLKWTVQICLRMPPSAVPIVPSGNACVVMGRMKILFFLQITRIPYGAVIGVGKDWKDSPSLVLPIVYDIQTNVTQLAERTGQVISPTMTAASTLLRRFAEFNAQQNQCTLFPAITDLLTNLQLAAEMPQPPPNQSIGPPVGVGVGVGSSPNPMMPMQQLPQQVGPQGPVGPGGYPQMGPNPGGPQ", "length": 1553 }, "evidence": [ { "id": "G3X6Y3", "url": "https://omabrowser.org/oma/group/G3X6Y3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y3", "url": "https://www.uniprot.org/uniprotkb/G3X6Y3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1031, "end_pos": 1033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1256, "end_pos": 1258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1404, "end_pos": 1406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1443, "end_pos": 1445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": 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"categories": [ "Protein" ] }, { "id": "G3X7J4-1", "url": "https://www.uniprot.org/uniprotkb/G3X7J4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDPCACPAVVGASPARAGDSERQSSPSRPAPSPVPPPGEPAQMVQGGGPRGGTRGACAERRLLSRGRTPLSHLPDKHHENSAAHTVAGTPSYTSLIPAHPPATLLASWMMSEQDLADVVQIAVEELSPGHPVVLENHVVTDEDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNSDRQNAVVAKMEDPLSGRAPEPLENVISNAVPGRRQNTIVVKVPGQEDSHNEDGESGSEASDSVSNCGQSGSQNIGNNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYGASETMMSTPPPSSELQQPPPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVTDHTAAAQAADALQPTLQPEMQLEHGAIQIQ", "length": 612, "header": "tr|G3X7J4-1|G3X7J4_BOVIN Isoform 1 of Protein BANP OS=Bos taurus OX=9913 GN=BANP PE=3 SV=4 CANONICAL=G3X7J4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NDW5-1", "url": 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of Protein BANP OS=Bos taurus OX=9913 GN=BANP PE=3 SV=4 CANONICAL=G3X7J4-1" }, "locus": { "chromosome": "18", "start_pos": 13449670, "end_pos": 13381283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032527.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032527.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032458.6", "url": "https://www.ensembl.org/id/ENSBTAP00000032458.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3X7J4", "url": "https://www.uniprot.org/uniprotkb/G3X7J4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX64-1", "uniprot_ac": "G3MX64", "uniprot_id": "G3MX64_BOVIN", "mass": { "chemical_mass": 29516.0, "monoisotopic_mass": 29516.0 }, "refseq": { "ac": "XP_002692875", "name": "carbonic anhydrase 13 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692875" }, "gene_names": [ { "name": "CA13", "type": "recommended", "evidence": [ { "id": "G3MX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ] }, { "name": "CA13", "type": "synonym", "evidence": [ { "id": "XP_002692875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692875" } ] } ], "protein_names": [ { "name": "Carbonic anhydrase", "type": "recommended", "evidence": [ { "id": "G3MX64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX64/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.1", "type": "synonym", "evidence": [ { "id": 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"database": "UniProtKB", "id": "G3MX64", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CA13", "url": "https://www.uniprot.org/uniprotkb/G3MX64", "locus": { "chromosome": "14", "start_pos": 77321781, "end_pos": 77371704, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001000", "url": "https://www.ensembl.org/id/ENSBTAG00000001000" } ] } } ], "crossref": [ { "id": "G3MX64", "url": "https://alphafold.ebi.ac.uk/entry/G3MX64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001000", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001000", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03119", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03119", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513850", "url": 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"A0A3Q1NEZ9", "url": "https://www.orthodb.org/?gene=A0A3Q1NEZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MIP9", "url": "https://www.orthodb.org/?gene=F1MIP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MX64", "url": "https://www.orthodb.org/?gene=G3MX64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18952:SF81", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18952:SF81", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1475029", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475029", "database": 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"https://www.uniprot.org/uniprotkb/G3MX64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGFSWGYGERDGPVHWNEFFPIADGDQQSPIEIKTKEVRYDSSLRPLGIKYDASSAKIISNSGHSFNVDFDDTDDKSVLRGGPLTGSYRLRQFHLHWGSTDDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGIFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPVCLLPPCRDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLAAFRTLLCSREGETAAFLLSNHRPPQPLKGRKVRASFR", "length": 262, "header": "tr|G3MX64-1|G3MX64_BOVIN Isoform 1 of Carbonic anhydrase OS=Bos taurus OX=9913 GN=CA13 PE=3 SV=2 CANONICAL=G3MX64-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NEZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEZ9/entry", "sequence": { "sequence": "MSGFSWGYGERDGPVHWNEFFPIADGDQQSPIEIKTKEVRYDSSLRPLGIKYDASSAKIISNSGHSFNVDFDDTDDKSVLRGGPLTGSYRLRQFHLHWGSTDDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGIFLQVWRWL", "length": 155, "header": "tr|A0A3Q1NEZ9-1|G3MX64_BOVIN Computationally mapped isoform of Carbonic anhydrase OS=Bos taurus OX=9913 GN=CA13 PE=3 SV=2 CANONICAL=G3MX64-1" }, "locus": { "chromosome": "14", "start_pos": 77371694, "end_pos": 77348373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069809.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069809.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070262.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070262.2" } ] } }, { "isoform_ac": "F1MIP9-1", "url": "https://www.uniprot.org/uniprotkb/F1MIP9/entry", "sequence": { "sequence": "MSGFSWGYGERDGPVHWNEFFPIADGDQQSPIEIKTKEVRYDSSLRPLGIKYDASSAKIISNSGHSFNVDFDDTDDKSVLRGGPLTGSYRLRQFHLHWGSTDDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGIFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPVCLLPPCRDYWTYPGSLTVPPLLESVTWIILKQPINISSQQKWEPGQMKLEVLLPQTMEGSVVLWSYPEACSLAEYTHLSLEFEI", "length": 267, "header": "tr|F1MIP9-1|F1MIP9_BOVIN Computationally mapped isoform of Carbonic anhydrase OS=Bos taurus OX=9913 GN=CA13 PE=3 SV=3 CANONICAL=G3MX64-1" }, "locus": { "chromosome": "14", "start_pos": 77371694, "end_pos": 77321917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001324.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001324.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001324.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001324.6" } ] } }, { "isoform_ac": "G3MX64-1", "url": "https://www.uniprot.org/uniprotkb/G3MX64/entry", "sequence": { "sequence": "MSGFSWGYGERDGPVHWNEFFPIADGDQQSPIEIKTKEVRYDSSLRPLGIKYDASSAKIISNSGHSFNVDFDDTDDKSVLRGGPLTGSYRLRQFHLHWGSTDDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGIFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPVCLLPPCRDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLAAFRTLLCSREGETAAFLLSNHRPPQPLKGRKVRASFR", "length": 262, "header": "tr|G3MX64-1|G3MX64_BOVIN Isoform 1 of Carbonic anhydrase OS=Bos taurus OX=9913 GN=CA13 PE=3 SV=2 CANONICAL=G3MX64-1" }, "locus": { "chromosome": "14", "start_pos": 77371694, "end_pos": 77334460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063585.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063585.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054124.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054124.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:513850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513850", "resource": "KEGG Pathway" }, { "id": "R-BTA-1475029", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475029", "resource": "Reactome", "description": "Reversible hydration of carbon dioxide" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UGB0-1", "protein_name": "Carbonic anhydrase", "gene_name": "CA13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRFSWGYGEHNGPVHWNEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFSVDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVKYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEHNSQLQKITDILDSIKEKGKQTRFTNFDPLSLLPPSWDYWTYPGSLTVPPLLESVTWIILKQPINISSQQLATFRTLLCTKEGEEAAFLLSNHRPLQPLKGRKVRASFH", "length": 262 }, "evidence": [ { "id": "G3MX64", "url": "https://omabrowser.org/oma/group/G3MX64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B5DFG6-1", "protein_name": "Carbonic anhydrase", "gene_name": "Ca13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLSWGYDEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY", "length": 262 }, "evidence": [ { "id": "G3MX64", "url": "https://omabrowser.org/oma/group/G3MX64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92051-1", "protein_name": "Carbonic anhydrase", "gene_name": "cahz", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAHAWGYGPADGPESWAESFPIANGPRQSPIDIVPTQAQHDPSLKHLKLKYDPATTKSILNNGHSFQVDFVDDDNSSTLAGGPITGIYRLRQFHFHWGSSDDKGSEHTIAGTKFPCELHLVHWNTKYPNFGEAASKPDGLAVVGVFLKIGAANPRLQKVLDALDDIKSKGRQTTFANFDPKTLLPASLDYWTYEGSLTTPPLLESVTWIVLKEPISVSPAQMAKFRSLLFSSEGETPCCMVDNYRPPQPLKGRKVRASFK", "length": 260 }, "evidence": [ { "id": "G3MX64", "url": "https://omabrowser.org/oma/group/G3MX64/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D6N1-1", "protein_name": "Carbonic anhydrase 13", "gene_name": "Ca13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY", "length": 262 }, "evidence": [ { "id": "G3MX64", "url": "https://omabrowser.org/oma/group/G3MX64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MX64", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MX64", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MX64", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "G3MX64", "url": "https://www.uniprot.org/uniprotkb/G3MX64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10748", "name": "", "equation": "hydrogencarbonate + H(+) = CO2 + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N5D1-1", "G3MX64-1", "E1BAD9-1", "E1BHA4-1", "F1MBS0-1", "F1MPL2-1", "Q95323-1", "P00921-1", "P18915-1", "Q1LZA1-1", "Q3SZX4-1", "F1N0H3-1", "E1BPA4-1", "A0A0A0MP99-1", "A0A3Q1LYT6-1" ], "evidence": [ { "id": "10748", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10748" } ] }, { "id": "R-BTA-1475022", "name": "Carbonic anhydrase dehydrates bicarbonate (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-111627" ], "output_participant_list": [], "enzyme_list": [ "G3MX64-1", "Q1LZA1-1", "Q3SZX4-1", "F1N0H3-1", "E1BHA4-1" ], "evidence": [ { "id": "R-BTA-1475022", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475022" } ] }, { "id": "R-BTA-1475026", "name": "Carbonic anhydrase hydrates carbon dioxide (cytosol)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MX64-1", "Q1LZA1-1", "Q3SZX4-1", "F1N0H3-1", "E1BHA4-1" ], "evidence": [ { "id": "R-BTA-1475026", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1475026" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-111627", "participant_name": "HCO3- [cytosol]", "crossref": [ { "id": "17544", "database": "ChEBI", "url": "" }, { "id": "11533114", "database": "PubChem Substance", "url": "" }, { "id": "C00288", "database": "COMPOUND", "url": "" }, { "id": "ZINC000006827693", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0A0MP99", "gene_name": "LOC100847874", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] }, { "ec_number": "4.2.1.69", "activity": "urea = cyanamide + H2O.", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] }, { "ec_number": "4.2.1.69", "activity": "", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" } ] } ] }, { "uniprot_ac": "A0A3Q1LYT6", "gene_name": "LOC784254", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "A0A3Q1LYT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYT6" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYT6" } ] } ] }, { "uniprot_ac": "E1BAD9", "gene_name": "CA5A", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BAD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAD9" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BAD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAD9" } ] } ] }, { "uniprot_ac": "E1BHA4", "gene_name": "CA7", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BHA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BHA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHA4" } ] } ] }, { "uniprot_ac": "E1BPA4", "gene_name": "CA9", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "E1BPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "E1BPA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA4" } ] } ] }, { "uniprot_ac": "F1MBS0", "gene_name": "CA6", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "F1MBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS0" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "F1MBS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS0" } ] } ] }, { "uniprot_ac": "F1MPL2", "gene_name": "CA12", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "F1MPL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPL2" } ] }, { "ec_number": 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"ENSBTAG00000004598", "url": "https://www.ensembl.org/id/ENSBTAG00000004598" } ] } } ], "crossref": [ { "id": "F6RNZ4", "url": "https://alphafold.ebi.ac.uk/entry/F6RNZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "510412", "url": "https://www.ncbi.nlm.nih.gov/gene/510412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13815:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13815:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005222238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RSF1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RSF1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RNZ4-1", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWFADLAGKAEDLLNRVDQGAATALSRKENTSNIIYSKNTDYSELHQQNTDLTYQTGSKSTYISSAADNIRNQKATILAGTANVKVGARTLGETSYPVENASAPRPSSQFVRRKKSEPDDELLFDFLNSSQKEPTGKVEIKKEKAKTPVLQSSRTSSVNSVNTSVTTIKAVEENPSGSQSHASHDSDSGHETHEDSSKENVLSNAACTDPNPVPNDDGRSHELSNLRLENQLLRNEVQNLNQEMASLLQRSKETQEELNKARARVEKWNVDHSKTDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLNTRTEALEALQSEKSRIIQDHSEGSSLQNQALQTLQERLHEADATLKREQESYKQMQSEFAARLNKMEVERQNLAEAVTLAERKHSDEKKRVDELQQQVKVLKSSLDSSKQELADYKQKATRILQSKEKLINSLKEGSGFEGLDSSTANSVELEELRHEKETQREEIQKLMGQIHQLRSELQDIEAQQVSEAESAREQLQDLQDQIAGQRAAKQELEAELDRQKQEFHYIEEDLYRTKNTLQSRIKDREDEIQKLRNQLTNKTLSNSSQSELENRLHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQINSAAGSSSNGSSINMAGVDSGEGTRLRNVPVLFNDTETNLAGMYGKVRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYTPEMHHDQPRGK", "length": 731, "header": "tr|F6RNZ4-1|F6RNZ4_BOVIN Isoform 1 of Golgin subfamily A member 5 OS=Bos taurus OX=9913 GN=GOLGA5 PE=4 SV=1 CANONICAL=F6RNZ4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RSF1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSF1/entry", "sequence": { "sequence": "MSWFADLAGKAEDLLNRVDQGAATALSRKENTSNIIYSKNTDYSELHQQNTDLTYQTGSKSTYISSAADNIRNQKATILAGTANVKVGARTLGETSYPVENASAPRPSSQFVRRKKSEPDDELLFDFLNSSQKEPTGKVEIKKEKAKTPVLQSSRTSSVNSVNTSVTTIKAVEENPSGSQSHAASHDSDSGHETHEDSSKENVLSNAACTDPNPVPNDDGRSHELSNLRLENQLLRNEVQNLNQEMASLLQRSKETQEELNKARARVEKWNVDHSKTDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLNTRTEALEALQSEKSRIIQDHSEGSSLQNQALQTLQERLHEADATLKREQESYKQMQSEFAARLNKMEVERQNLAEAVTLAERKHSDEKKRVDELQQQVKVLKSSLDSSKQELADYKQKATRILQSKEKLINSLKEGSGFEGLDSSTANSVELEELRHEKETQREEIQKLMGQIHQLRSELQDIEAQQVSEAESAREQLQDLQDQIAGQRAAKQELEAELDRQKQEFHYIEEDLYRTKNTLQSRIKDREDEIQKLRNQLTNKTLSNSSQSELENRLHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQINSAAGSSSNGSSINMAGVDSGEASVWEFFCEDIPSHEFL", "length": 666, "header": "tr|A0AAA9RSF1-1|F6RNZ4_BOVIN Computationally mapped isoform of Golgin subfamily A member 5 OS=Bos taurus OX=9913 GN=GOLGA5 PE=4 SV=1 CANONICAL=F6RNZ4-1" }, "locus": { "chromosome": "21", "start_pos": 57505836, "end_pos": 57481162, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099314.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099314.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075485.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075485.1" } ] } }, { "isoform_ac": "F6RNZ4-1", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4/entry", "sequence": { "sequence": "MSWFADLAGKAEDLLNRVDQGAATALSRKENTSNIIYSKNTDYSELHQQNTDLTYQTGSKSTYISSAADNIRNQKATILAGTANVKVGARTLGETSYPVENASAPRPSSQFVRRKKSEPDDELLFDFLNSSQKEPTGKVEIKKEKAKTPVLQSSRTSSVNSVNTSVTTIKAVEENPSGSQSHASHDSDSGHETHEDSSKENVLSNAACTDPNPVPNDDGRSHELSNLRLENQLLRNEVQNLNQEMASLLQRSKETQEELNKARARVEKWNVDHSKTDRITRELRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLNTRTEALEALQSEKSRIIQDHSEGSSLQNQALQTLQERLHEADATLKREQESYKQMQSEFAARLNKMEVERQNLAEAVTLAERKHSDEKKRVDELQQQVKVLKSSLDSSKQELADYKQKATRILQSKEKLINSLKEGSGFEGLDSSTANSVELEELRHEKETQREEIQKLMGQIHQLRSELQDIEAQQVSEAESAREQLQDLQDQIAGQRAAKQELEAELDRQKQEFHYIEEDLYRTKNTLQSRIKDREDEIQKLRNQLTNKTLSNSSQSELENRLHQLTETLIQKQTMLESLSTEKNSLVFQLERLEQQINSAAGSSSNGSSINMAGVDSGEGTRLRNVPVLFNDTETNLAGMYGKVRKAASSIDQFSIRLGIFLRRYPIARVFVIIYMALLHLWVMIVLLTYTPEMHHDQPRGK", "length": 731, "header": "tr|F6RNZ4-1|F6RNZ4_BOVIN Isoform 1 of Golgin subfamily A member 5 OS=Bos taurus OX=9913 GN=GOLGA5 PE=4 SV=1 CANONICAL=F6RNZ4-1" }, "locus": { "chromosome": "21", "start_pos": 57507259, "end_pos": 57481162, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006036.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006036.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006036.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006036.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4" } ], "pmid": "" }, { "name": "Golgi cisterna", "id": "GO:0031985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031985", "evidence": [ { "database": "UniProtKB", "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F6RNZ4", "url": "https://www.uniprot.org/uniprotkb/F6RNZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 660, "end_pos": 662 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RJT0-1", "uniprot_ac": "F6RJT0", "uniprot_id": "F6RJT0_BOVIN", "mass": { "chemical_mass": 57824.0, "monoisotopic_mass": 57824.0 }, "refseq": {}, "gene_names": [ { "name": "PDIA3", "type": "recommended", "evidence": [ { "id": "F6RJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ] } ], "protein_names": [ { "name": "Protein disulfide-isomerase", "type": "recommended", "evidence": [ { "id": "F6RJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJT0/entry#names_and_taxonomy" } ] }, { "name": "5.3.4.1", "type": "synonym", "evidence": [ { "id": "F6RJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJT0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Protein disulfide isomerase that catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds in client proteins and functions as a protein folding chaperone. Core component of the major histocompatibility complex class I (MHC I) peptide loading complex where it functions as an essential folding chaperone for TAPBP. Through TAPBP, assists the dynamic assembly of the MHC I complex with high affinity antigens in the endoplasmic reticulum. Therefore, plays a crucial role in the presentation of antigens to cytotoxic T cells in adaptive immunity.", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0#function" }, { "database": "UniProtKB", "id": "ARBA00045713", "url": "https://www.uniprot.org/uniprotkb/ARBA00045713#function" }, { "database": "UniProtKB", "id": "A0AAA9RTF0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF0#function" }, { "database": "UniProtKB", "id": "A0AAA9TVJ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ6#function" }, { "database": "UniProtKB", "id": "A0AAA9SVD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVD1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDIA3", "url": "https://www.uniprot.org/uniprotkb/F6RJT0", "locus": { "chromosome": "21", "start_pos": 55392458, "end_pos": 55370251, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017196", "url": "https://www.ensembl.org/id/ENSBTAG00000017196" } ] } } ], "crossref": [ { "id": "F6RJT0", "url": "https://alphafold.ebi.ac.uk/entry/F6RJT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02995", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02995", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03069", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03069", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03073", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03073", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18929", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18929", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18929:SF132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18929:SF132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13848", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13848", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RTF0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVJ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJT0-1", "url": "https://www.uniprot.org/uniprotkb/F6RJT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLRRLALFPGLALLLAAARLAAASDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPASVPLKSEEEFEKFISDKDASVVGFFKDLFSEAHSEFLKAASNLRDNYRFAHTNVESLVNKYDDDGEGITLFRPSHLTNKFEDKTVAYTEQKMTSGKIKRFIQENIFGICPHMTEDNKDLLQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGKKLHFAVASRKTFSHELSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFDGNLKRYLKSEPIPESNDGPVKRIFCVFQVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFISYLKREATNPPVIQEEKPKKKKKAQEDL", "length": 512, "header": "tr|F6RJT0-1|F6RJT0_BOVIN Isoform 1 of Protein disulfide-isomerase OS=Bos taurus OX=9913 GN=PDIA3 PE=3 SV=1 CANONICAL=F6RJT0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RTF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF0/entry", "sequence": { "sequence": "MRLRRLALFPGLALLLAAARLAAASDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPASVPLKSEEEFEKFISDKDASVVGFFKDLFSEAHSEFLKAASNLRDNYRFAHTNVESLVNKYDDDGEGITLFRPSHLTNKFEDKTVAYTEQKMTSGKIKRFIQENIFGICPHMTEDNKDLLQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGKKLHFAVASRKTFSHELSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFDGNLKRYLKSEPIPESNDGPVKLRKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFISYLKREATNPPVIQEEKPKKKKKAQEDL", "length": 462, "header": "tr|A0AAA9RTF0-1|F6RJT0_BOVIN Computationally mapped isoform of Protein disulfide-isomerase OS=Bos taurus OX=9913 GN=PDIA3 PE=3 SV=1 CANONICAL=F6RJT0-1" }, "locus": { "chromosome": "21", "start_pos": 55392126, "end_pos": 55370339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133788.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133788.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076229.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076229.1" } ] } }, { "isoform_ac": "A0AAA9SVD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVD1/entry", "sequence": { "sequence": "MRLRRLALFPGLALLLAAARLAAASDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPASVPLKSEEEFEKFISDKDASVVGFFKDLFSEAHSEFLKAASNLRDNYRFAHTNVESLVNKYDDDGEGITLFRPSHLTNKFEDKTVAYTEQKMTSGKIKRFIQENIFGICPHMTEDNKDLLQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGKKLHFAVASRKTFSHELSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFDGNLKRYLKSEPIPESNDGPVKGGRELSDFISYLKREATNPPVIQEEKPKKKKKAQEDL", "length": 416, "header": "tr|A0AAA9SVD1-1|F6RJT0_BOVIN Computationally mapped isoform of Protein disulfide-isomerase OS=Bos taurus OX=9913 GN=PDIA3 PE=3 SV=1 CANONICAL=F6RJT0-1" }, "locus": { "chromosome": "21", "start_pos": 55392126, "end_pos": 55370339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087896.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087896.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090426.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090426.1" } ] } }, { "isoform_ac": "A0AAA9TVJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ6/entry", "sequence": { "sequence": "MRLRRLALFPGLALLLAAARLAAASDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPASVPLKSEEEFEKFISDKDASVVGFFKDLFSEAHSEFLKAASNLRDNYRFAHTNVESLVNKYDDDGEGITLFRPSHLTNKFEDKTVAYTEQKMTSGKIKRFIQENIFGICPHMTEDNKDLLQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGKKLHFAVASRKTFSHELSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRKDPNIVIAKMDATANDVPSPYEVRGVAVN", "length": 453, "header": "tr|A0AAA9TVJ6-1|F6RJT0_BOVIN Computationally mapped isoform of Protein disulfide-isomerase OS=Bos taurus OX=9913 GN=PDIA3 PE=3 SV=1 CANONICAL=F6RJT0-1" }, "locus": { "chromosome": "21", "start_pos": 55392028, "end_pos": 55370339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118107.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118107.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100602.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100602.1" } ] } }, { "isoform_ac": "F6RJT0-1", "url": "https://www.uniprot.org/uniprotkb/F6RJT0/entry", "sequence": { "sequence": "MRLRRLALFPGLALLLAAARLAAASDVLELTDDNFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEESGAYDGPRTADGIVSHLKKQAGPASVPLKSEEEFEKFISDKDASVVGFFKDLFSEAHSEFLKAASNLRDNYRFAHTNVESLVNKYDDDGEGITLFRPSHLTNKFEDKTVAYTEQKMTSGKIKRFIQENIFGICPHMTEDNKDLLQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGKKLHFAVASRKTFSHELSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFDGNLKRYLKSEPIPESNDGPVKRIFCVFQVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFISYLKREATNPPVIQEEKPKKKKKAQEDL", "length": 512, "header": "tr|F6RJT0-1|F6RJT0_BOVIN Isoform 1 of Protein disulfide-isomerase OS=Bos taurus OX=9913 GN=PDIA3 PE=3 SV=1 CANONICAL=F6RJT0-1" }, "locus": { "chromosome": "21", "start_pos": 55392126, "end_pos": 55370339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022854.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022854.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022854.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022854.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "MHC class I peptide loading complex", "id": "GO:0042824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042824", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "peptide antigen assembly with MHC class I protein complex", "id": "GO:0002502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002502", "evidence": [ { "database": "UniProtKB", "id": "F6RJT0", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJT0" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 133, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.3.4.1", "ec_name": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "5.3.4.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.3.4.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3Y2-1", "uniprot_ac": "G3N3Y2", "uniprot_id": "G3N3Y2_BOVIN", "mass": { "chemical_mass": 72142.0, "monoisotopic_mass": 72142.0 }, "refseq": { "ac": "XP_024832823", "name": "proline dehydrogenase 1, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832823" }, "gene_names": [ { "name": "PRODH", "type": "recommended", "evidence": [ { "id": "G3N3Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ] }, { "name": "PRODH", "type": "synonym", "evidence": [ { "id": "XP_024832823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832823" } ] } ], "protein_names": [ { "name": "Proline dehydrogenase", "type": "recommended", "evidence": [ { "id": "G3N3Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2/entry#names_and_taxonomy" } ] }, { "name": "1.5.5.2", "type": "synonym", "evidence": [ { "id": "G3N3Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2/entry#names_and_taxonomy" } ] }, { "name": "proline dehydrogenase 1, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024832823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832823" } ] } ], "function": [ { "annotation": "Converts proline to delta-1-pyrroline-5-carboxylate.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TE69", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE69#function" }, { "database": "UniProtKB", "id": "RU364054", "url": "https://www.uniprot.org/uniprotkb/RU364054#function" }, { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2#function" }, { "database": "UniProtKB", "id": "A0AAA9RUQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUQ0#function" }, { "database": "UniProtKB", "id": "ARBA00057042", "url": "https://www.uniprot.org/uniprotkb/ARBA00057042#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRODH", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2", "locus": {} } ], "crossref": [ { "id": "G3N3Y2", "url": "https://alphafold.ebi.ac.uk/entry/G3N3Y2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047676", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047676", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505094", "url": "https://www.ncbi.nlm.nih.gov/gene/505094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13914:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13914:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-70688", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70688", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024832823", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832823", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23784", "url": "https://www.rhea-db.org/rhea/23784", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RUQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE69", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE69-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3Y2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLRRTSWMHFSALCRRAPLSTAPAAREQPAAGPGAEPVCGPAETARPPVPAVDFGNTQEAYRSRRSWELARSLLVLSLCASPALLARHEQLLHLARKLLGQRLFNTLMKMTFYGQFVAGEDQESIRPLIQHNRAFGVGSILDYGVEEDLTPEEAERTEMESCSSALERDGCGVSKREKQFQAHRAFGDRRDGVTSARTYFYASEAKCDSHMETFLHCIEASGGASEDGFSAIKLTALGRPQFLLQFSDMLTKWRRFFHHVAAEQGKAGLAAVDTKLEVAALQESVVKMGIASRAEIEDWFTAETLGVSGTLDLLDWCSLIDSRTELSRHLVVPNMQTGRLEPLLSQFTEEEERQMTRMLQRMDVLAKKANQVGVRLMVDAEQTYFQPAISRLTLEMQRRFNVERPLIFNTFQCYLRDAYDNVILDVELARREGWCFGAKLVRGAYMAQERARALEVGYEDPINPTYEATSAVYHRCLDYVLEELKHNARAAVMVASHNEDTVRFTLRRGPCVFDVCSASQLRPSILQRLSGHQWLVTEVCTGQPARGGMEELGLHPADRQVYFGQLLGMCDHISFPLGQAGFPVYKYVPYGPVMEVLPYLSRRALENSGVMKGAQRERQLLWQELKRRLCTRSLFHQPA", "length": 640, "header": "tr|G3N3Y2-1|G3N3Y2_BOVIN Isoform 1 of Proline dehydrogenase OS=Bos taurus OX=9913 GN=PRODH PE=3 SV=3 CANONICAL=G3N3Y2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RUQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUQ0/entry", "sequence": { "sequence": "MGLRRTSWMHFSALCRRAPLSTAPAAREQPAAGPGAEPVCGPAETARPPVPAVDFGNTQEAYRSRRSWELARSLLVLSLCASPALLARHEQLLHLARKLLGQRLFNTLMKMTFYGQFVAGEDQESIRPLIQHNRAFGVGSILDYGVEEDLTPEEAERTEMESCSSALERDGCGVSKREKQFQAHRAFGDRRDGVTSARTYFYASEAKCDSHMETFLHCIEASGGASEDGFSAIKLTALGRPQFLESVVKMGIASRAEIEDWFTAETLGVSGTLDLLDWCSLIDSRTELSRHLVVPNMQTGRLEPLLSQFTEEEERQMTRMLQRMDVLAKKANQVGVRLMVDAEQTYFQPAISRLTLEMQRRFNVERPLIFNTFQCYLRDAYDNVILDVELARREGWCFGAKLVRGAYMAQERARALEVGYEDPINPTYEATSAVYHRCLDYVLEELKHNARAAVMVASHNEDTVRFTLRRMEELGLHPADRQVYFGQLLGMCDHISFPLGQAGFPVYKYVPYGPVMEVLPYLSRRALENSGVMKGAQRERQLLWQELKRRLCTRSLFHQPA", "length": 561, "header": "tr|A0AAA9RUQ0-1|G3N3Y2_BOVIN Computationally mapped isoform of Proline dehydrogenase OS=Bos taurus OX=9913 GN=PRODH PE=3 SV=1 CANONICAL=G3N3Y2-1" }, "locus": { "chromosome": "17", "start_pos": 73123144, "end_pos": 73105800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128758.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128758.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074667.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074667.1" } ] } }, { "isoform_ac": "A0AAA9TE69-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE69/entry", "sequence": { "sequence": "MGLRRTSWMHFSALCRRAPLSTAPAAREQPAAGPGAEPVCGPAETARPPVPAVDFGNTQEAYRSRRSWELARSLLVLSLCASPALLARHEQLLHLARKLLGQRLFNTLMKMTFYGQFVAGEDQESIRPLIQHNRAFGVGSILDYGVEEDLTPEEAERTEMESCSSALERDGCGVSKREKQFQAHRAFGDRRDGVTSARTYFYASEAKCDSHMETFLHCIEASGGASEDGFSAIKLTALGRPQFLLQFSDMLTKWRRFFHHVAAEQGKAGLAAVDTKLEVAALQESVVKMGIASRAEIEDWFTAETLGVSGTLDLLDWCSLIDSRTELSRHLVVPNMQTGRLEPLLSQFTEEEERQMTRMLQRMDVLAKKANQVGVRLMVDAEQTYFQPAISRLTLEMQRRFNVERPLIFNTFQCYLRDAYDNVILDVELARREGWCFGAKLVRGAYMAQERARALEVGYEDPINPTYEATSAVYHRCLDYVLEELKHNARAAVMVASHNEDTVRFTLRRMEELGLHPADRQVYFGQLLGMCDHISFPLAGRTCRPLLCSCGLRPTPARRAGSRQELLCPPPRPWTLRTTFPRVQPWRPEPHTGQRLAAEAGLSINHFSTASSPRLRLREWL", "length": 621, "header": "tr|A0AAA9TE69-1|G3N3Y2_BOVIN Computationally mapped isoform of Proline dehydrogenase OS=Bos taurus OX=9913 GN=PRODH PE=3 SV=1 CANONICAL=G3N3Y2-1" }, "locus": { "chromosome": "17", "start_pos": 73123479, "end_pos": 73105800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105401.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105401.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094468.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094468.1" } ] } }, { "isoform_ac": "G3N3Y2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2/entry", "sequence": { "sequence": "MGLRRTSWMHFSALCRRAPLSTAPAAREQPAAGPGAEPVCGPAETARPPVPAVDFGNTQEAYRSRRSWELARSLLVLSLCASPALLARHEQLLHLARKLLGQRLFNTLMKMTFYGQFVAGEDQESIRPLIQHNRAFGVGSILDYGVEEDLTPEEAERTEMESCSSALERDGCGVSKREKQFQAHRAFGDRRDGVTSARTYFYASEAKCDSHMETFLHCIEASGGASEDGFSAIKLTALGRPQFLLQFSDMLTKWRRFFHHVAAEQGKAGLAAVDTKLEVAALQESVVKMGIASRAEIEDWFTAETLGVSGTLDLLDWCSLIDSRTELSRHLVVPNMQTGRLEPLLSQFTEEEERQMTRMLQRMDVLAKKANQVGVRLMVDAEQTYFQPAISRLTLEMQRRFNVERPLIFNTFQCYLRDAYDNVILDVELARREGWCFGAKLVRGAYMAQERARALEVGYEDPINPTYEATSAVYHRCLDYVLEELKHNARAAVMVASHNEDTVRFTLRRGPCVFDVCSASQLRPSILQRLSGHQWLVTEVCTGQPARGGMEELGLHPADRQVYFGQLLGMCDHISFPLGQAGFPVYKYVPYGPVMEVLPYLSRRALENSGVMKGAQRERQLLWQELKRRLCTRSLFHQPA", "length": 640, "header": "tr|G3N3Y2-1|G3N3Y2_BOVIN Isoform 1 of Proline dehydrogenase OS=Bos taurus OX=9913 GN=PRODH PE=3 SV=3 CANONICAL=G3N3Y2-1" }, "locus": { "chromosome": "17", "start_pos": 73123144, "end_pos": 73105800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000062994.3", "url": "https://www.ensembl.org/id/ENSBTAT00000062994.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056646.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056646.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-70688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70688", "resource": "Reactome", "description": "Proline catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "L-proline catabolic process", "id": "GO:0006562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006562", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ], "pmid": "" }, { "name": "L-proline catabolic process to L-glutamate", "id": "GO:0010133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010133", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "proline dehydrogenase activity", "id": "GO:0004657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004657", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y2", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23784", "name": "", "equation": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MZH9-1", "G3N3Y2-1", "A6QQ74-1", "Q148G5-1" ], "evidence": [ { "id": "23784", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23784" } ] }, { "id": "R-BTA-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-379717", "R-ALL-113597" ], "output_participant_list": [ "R-ALL-113590", "R-ALL-164934" ], "enzyme_list": [ "G3N3Y2-1" ], "evidence": [ { "id": "R-BTA-70670", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70670" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113590", "participant_name": "1PYR-5COOH [mitochondrial matrix]", "crossref": [ { "id": "8144614", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000003870284", "database": "ZINC", "url": "" }, { "id": "C03912", "database": "COMPOUND", "url": "" }, { "id": "17388", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-113597", "participant_name": "FAD [mitochondrial inner membrane]", "crossref": [ { "id": "57692", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215434", "database": "ZINC", "url": "" }, { "id": "ZINC000195756838", "database": "ZINC", "url": "" }, { "id": "C00016", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-164934", "participant_name": "FADH2 [mitochondrial inner membrane]", "crossref": [ { "id": "ZINC000095099885", "database": "ZINC", "url": "" }, { "id": "C01352", "database": "COMPOUND", "url": "" }, { "id": "58307", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-379717", "participant_name": "L-Pro [mitochondrial matrix]", "crossref": [ { "id": "60039", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895360", "database": "ZINC", "url": "" }, { "id": "C00148", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A6QQ74", "gene_name": "PRODH2", "activity": [ { "ec_number": "1.5.5.3", "activity": "trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "A6QQ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQ74" } ] }, { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "A6QQ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQ74" } ] }, { "ec_number": "1.5.5.3", "activity": "", "evidence": [ { "id": "A6QQ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQ74" } ] } ] }, { "uniprot_ac": "F1MZH9", "gene_name": "PRODH2", "activity": [ { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "F1MZH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZH9" } ] }, { "ec_number": "1.5.5.2", "activity": "", "evidence": [ { "id": "F1MZH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZH9" } ] } ] }, { "uniprot_ac": "G3N3Y2", "gene_name": "PRODH", "activity": [ { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "G3N3Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ] }, { "ec_number": "1.5.5.2", "activity": "", "evidence": [ { "id": "G3N3Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" } ] } ] }, { "uniprot_ac": "Q148G5", "gene_name": "PRODH", "activity": [ { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "Q148G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148G5" } ] }, { "ec_number": "1.5.5.2", "activity": "", "evidence": [ { "id": "Q148G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148G5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3Y2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 640, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3Y2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3Y2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y2" }, { "id": "PF01619", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01619" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proline dehydrogenase", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 507, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.5.2", "ec_name": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "1.5.5.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.5.2" }, { "id": "1.5.5.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.5.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RWD2-1", "uniprot_ac": "F6RWD2", "uniprot_id": "F6RWD2_BOVIN", "mass": { "chemical_mass": 38725.0, "monoisotopic_mass": 38725.0 }, "refseq": { "ac": "XP_005203237", "name": "dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203237" }, "gene_names": [ { "name": "DHDDS", "type": "recommended", "evidence": [ { "id": "F6RWD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ] }, { "name": "DHDDS", "type": "synonym", "evidence": [ { "id": "XP_005203237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203237" } ] } ], "protein_names": [ { "name": "Alkyl transferase", "type": "recommended", "evidence": [ { "id": "F6RWD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWD2/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.-", "type": "synonym", "evidence": [ { "id": "F6RWD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWD2/entry#names_and_taxonomy" } ] }, { "name": "dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005203237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203237" } ] } ], "function": [ { "annotation": "With NUS1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Synthesizes long-chain polyprenols, mostly of C95 and C100 chain length. Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S4R9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4R9#function" }, { "database": "UniProtKB", "id": "ARBA00054429", "url": "https://www.uniprot.org/uniprotkb/ARBA00054429#function" }, { "database": "UniProtKB", "id": "A0AAA9TB76", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB76#function" }, { "database": "UniProtKB", "id": "ARBA00058504", "url": "https://www.uniprot.org/uniprotkb/ARBA00058504#function" }, { "database": "UniProtKB", "id": "A0AAA9RV84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV84#function" }, { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DHDDS", "url": "https://www.uniprot.org/uniprotkb/F6RWD2", "locus": { "chromosome": "2", "start_pos": 126666826, "end_pos": 126704421, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003235", "url": "https://www.ensembl.org/id/ENSBTAG00000003235" } ] } } ], "crossref": [ { "id": "F6RWD2", "url": "https://alphafold.ebi.ac.uk/entry/F6RWD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003235", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003235", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00475", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00475", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "523264", "url": "https://www.ncbi.nlm.nih.gov/gene/523264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6RWD2", "url": "https://www.orthodb.org/?gene=F6RWD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10291:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10291:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-446199", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446199", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005203237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "53008", "url": "https://www.rhea-db.org/rhea/53008", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RV84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0F4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0F4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4R9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4R9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB76", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB76-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWD2-1", "url": "https://www.uniprot.org/uniprotkb/F6RWD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWVKEGELSFWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAREKFSRLMEEQEKLQKHGVCIRVLGDLHLLPLDLQELVAQAVQTTKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDVSESLLDKCLYTNHSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLCEAILQFQMNHSMLQQKARDMYAEERKRQQLERDQAAVTEQLLQEGLPASGDPQLRRTRLHKLSARREERVQGFLQALELKRADWLAHLGTAST", "length": 334, "header": "tr|F6RWD2-1|F6RWD2_BOVIN Isoform 1 of Alkyl transferase OS=Bos taurus OX=9913 GN=DHDDS PE=3 SV=2 CANONICAL=F6RWD2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RV84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV84/entry", "sequence": { "sequence": "MSWVKEGELSFWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAREKFSRLMEEQEKLQKHGVCIRVLGDLHLLPLDLQELVAQAVQTTKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDVSESLLDKCLYTNHSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLCEAILQFQMNHSMLQTSLQKSTLLIPSLGQFPWHGDSGCSSEYHVTTEGPRHVCRGAEEAAAGEGPGCSDRAAAARGAPGQWGPPAPTDTLAQTLSQTGRAGPGLPASLGTQAG", "length": 354, "header": "tr|A0AAA9RV84-1|F6RWD2_BOVIN Computationally mapped isoform of Alkyl transferase OS=Bos taurus OX=9913 GN=DHDDS PE=3 SV=1 CANONICAL=F6RWD2-1" }, "locus": { "chromosome": "2", "start_pos": 126703755, "end_pos": 126667864, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124184.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124184.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077206.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077206.1" } ] } }, { "isoform_ac": "A0AAA9S0F4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0F4/entry", "sequence": { "sequence": "MSWVKEGELSFWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAREKFSRLMEEQEKLQKHGVCIRVLGDLHLLPLDLQELVAQAVQTTKNYNNDVSESLLDKCLYTNHSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLCEAILQFQMNHSMLQKARDMYAEERKRQQLERDQAAVTEQLLQEGLPASGDPQLRRTRLHKLSARREERVQGFLQALELKRADWLAHLGTAST", "length": 299, "header": "tr|A0AAA9S0F4-1|F6RWD2_BOVIN Computationally mapped isoform of Alkyl transferase OS=Bos taurus OX=9913 GN=DHDDS PE=3 SV=1 CANONICAL=F6RWD2-1" }, "locus": { "chromosome": "2", "start_pos": 126703755, "end_pos": 126667830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104033.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104033.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075542.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075542.1" } ] } }, { "isoform_ac": "A0AAA9S4R9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4R9/entry", "sequence": { "sequence": "MSWVKEGELSFWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAREKFSRLMEEQCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDVSESLLDKCLYTNHSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLCEAILQFQMNHSMLQKARDMYAEERKRQQLERDQAAVTEQLLQEGLPASGDPQLRRTRLHKLSARREERVQGFLQALELKRADWLAHLGTAST", "length": 294, "header": "tr|A0AAA9S4R9-1|F6RWD2_BOVIN Computationally mapped isoform of Alkyl transferase OS=Bos taurus OX=9913 GN=DHDDS PE=3 SV=1 CANONICAL=F6RWD2-1" }, "locus": { "chromosome": "2", "start_pos": 126703755, "end_pos": 126667830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089281.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089281.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077133.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077133.1" } ] } }, { "isoform_ac": "A0AAA9TB76-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB76/entry", "sequence": { "sequence": "MSWVKEGELSFWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAREKFSRLMEEQEKLQKHGVCIRVLGDLHLLPLDLQELVAQAVQTTKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDVSESLLDKCLYTNHSPHPDILIRTSGEVRLSDFLLWQKARDMYAEERKRQQLERDQAAVTEQLLQEGLPASGDPQLRRTRLHKLSARREERVQGFLQALELKRADWLAHLGTAST", "length": 297, "header": "tr|A0AAA9TB76-1|F6RWD2_BOVIN Computationally mapped isoform of Alkyl transferase OS=Bos taurus OX=9913 GN=DHDDS PE=3 SV=1 CANONICAL=F6RWD2-1" }, "locus": { "chromosome": "2", "start_pos": 126703755, "end_pos": 126667830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095910.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095910.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095959.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095959.1" } ] } }, { "isoform_ac": "A0AAA9TR17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR17/entry", "sequence": { "sequence": "MSWVKEGELSFWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAREKFSRLMEEHDVSESLLDKCLYTNHSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLCEAILQFQMNHSMLQKARDMYAEERKRQQLERDQAAVTEQLLQEGLPASGDPQLRRTRLHKLSARREERVQGFLQALELKRADWLAHLGTAST", "length": 260, "header": "tr|A0AAA9TR17-1|F6RWD2_BOVIN Computationally mapped isoform of Alkyl transferase OS=Bos taurus OX=9913 GN=DHDDS PE=3 SV=1 CANONICAL=F6RWD2-1" }, "locus": { "chromosome": "2", "start_pos": 126703755, "end_pos": 126667830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098882.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098882.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100809.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100809.1" } ] } }, { "isoform_ac": "F6RWD2-1", "url": "https://www.uniprot.org/uniprotkb/F6RWD2/entry", "sequence": { "sequence": "MSWVKEGELSFWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAREKFSRLMEEQEKLQKHGVCIRVLGDLHLLPLDLQELVAQAVQTTKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDVSESLLDKCLYTNHSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLCEAILQFQMNHSMLQQKARDMYAEERKRQQLERDQAAVTEQLLQEGLPASGDPQLRRTRLHKLSARREERVQGFLQALELKRADWLAHLGTAST", "length": 334, "header": "tr|F6RWD2-1|F6RWD2_BOVIN Isoform 1 of Alkyl transferase OS=Bos taurus OX=9913 GN=DHDDS PE=3 SV=2 CANONICAL=F6RWD2-1" }, "locus": { "chromosome": "2", "start_pos": 126703755, "end_pos": 126667830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010328.5", "url": "https://www.ensembl.org/id/ENSBTAT00000010328.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010328.5", "url": "https://www.ensembl.org/id/ENSBTAP00000010328.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-446199", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446199", "resource": "Reactome", "description": "Synthesis of dolichyl-phosphate" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" }, { "name": "ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity", "id": "GO:0045547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045547", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" }, { "name": "dehydrodolichyl diphosphate synthase complex", "id": "GO:1904423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904423", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" }, { "name": "dolichyl diphosphate biosynthetic process", "id": "GO:0006489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006489", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" }, { "name": "polyprenol biosynthetic process", "id": "GO:0016094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016094", "evidence": [ { "database": "UniProtKB", "id": "F6RWD2", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "53008", "name": "", "equation": "n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWD2-1", "A0A3Q1MAW4-1" ], "evidence": [ { "id": "53008", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53008" } ] }, { "id": "R-BTA-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, cytoplasmic side of endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-4419987" ], "output_participant_list": [ "R-ALL-4419982" ], "enzyme_list": [ "F6RWD2-1", "A0A3Q1MAW4-1" ], "evidence": [ { "id": "R-BTA-4419978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4419978" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-4419982", "participant_name": "pPPP [cytoplasmic side of endoplasmic reticulum membrane]", "crossref": [ { "id": "136960", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-4419987", "participant_name": "E,E-FPP [cytosol]", "crossref": [ { "id": "175763", "database": "ChEBI", "url": "" }, { "id": "ZINC000012494625", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MAW4", "gene_name": "NUS1", "activity": [ { "ec_number": "2.5.1.87", "activity": "n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate.", "evidence": [ { "id": "A0A3Q1MAW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAW4" } ] }, { "ec_number": "2.5.1.87", "activity": "", "evidence": [ { "id": "A0A3Q1MAW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAW4" } ] } ] }, { "uniprot_ac": "F6RWD2", "gene_name": "DHDDS", "activity": [ { "ec_number": "2.5.1.87", "activity": "n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate.", "evidence": [ { "id": "F6RWD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ] }, { "ec_number": "2.5.1.87", "activity": "", "evidence": [ { "id": "F6RWD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWD2" } ] }, { "ec_number": "2.5.1.-", "activity": "", "evidence": [ { "id": 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"https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100301169", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301169", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFQQMNL", "url": "https://omabrowser.org/oma/group/IFQQMNL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MY77", "url": "https://www.orthodb.org/?gene=G3MY77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12692", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12692", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12692:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12692:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5223345", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5223345", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9931295", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9931295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001231247", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231247", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RYP4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYP4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAE6", "url": 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"MAARWWRWCVCAIMAVALLLVFGVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS", "length": 335, "header": "tr|G3MY77-1|G3MY77_BOVIN Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 OS=Bos taurus OX=9913 GN=MAGT1 PE=3 SV=2 CANONICAL=G3MY77-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RYP4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYP4/entry", "sequence": { "sequence": "MAARWWRWCVCAIMAVALLLVFGVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKTF", "length": 302, "header": "tr|A0AAA9RYP4-1|G3MY77_BOVIN Computationally mapped isoform of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 OS=Bos taurus OX=9913 GN=MAGT1 PE=3 SV=1 CANONICAL=G3MY77-1" }, "locus": { "chromosome": "X", "start_pos": 74564276, "end_pos": 74517619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119854.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119854.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074921.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074921.1" } ] } }, { "isoform_ac": "A0AAA9TAE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAE6/entry", "sequence": { "sequence": "MAARWWRWCVCAIMAVALLLVFGVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS", "length": 305, "header": "tr|A0AAA9TAE6-1|G3MY77_BOVIN Computationally mapped isoform of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 OS=Bos taurus OX=9913 GN=MAGT1 PE=3 SV=1 CANONICAL=G3MY77-1" }, "locus": { "chromosome": "X", "start_pos": 74564284, "end_pos": 74517619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105391.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105391.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094994.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094994.1" } ] } }, { "isoform_ac": "A0AAA9TNU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNU6/entry", "sequence": { "sequence": "MAARWWRWCVCAIMAVALLLVFGVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS", "length": 241, "header": "tr|A0AAA9TNU6-1|G3MY77_BOVIN Computationally mapped isoform of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 OS=Bos taurus OX=9913 GN=MAGT1 PE=3 SV=1 CANONICAL=G3MY77-1" }, "locus": { "chromosome": "X", "start_pos": 74564284, "end_pos": 74517619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134035.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134035.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098898.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098898.1" } ] } }, { "isoform_ac": "G3MY77-1", "url": "https://www.uniprot.org/uniprotkb/G3MY77/entry", "sequence": { "sequence": "MAARWWRWCVCAIMAVALLLVFGVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS", "length": 335, "header": "tr|G3MY77-1|G3MY77_BOVIN Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 OS=Bos taurus OX=9913 GN=MAGT1 PE=3 SV=2 CANONICAL=G3MY77-1" }, "locus": { "chromosome": "X", "start_pos": 74564284, "end_pos": 74517619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065645.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065645.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054505.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054505.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100301169", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301169", "resource": "KEGG Pathway" }, { "id": "R-BTA-5223345", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5223345", "resource": "Reactome", "description": "Miscellaneous transport and binding events" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-9931295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9931295", "resource": "Reactome", "description": "PD-L1(CD274) glycosylation and translocation to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "O35777-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "Magt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPRWLWCVCATAAVTLLLVSKVPSASAQRKKEKVLVEKVIQLMEWTNQRPVIRMNGDKFRPLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANFWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPPKGKPKRADTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAAASDMDIGKRRMMCIAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS", "length": 335 }, "evidence": [ { "id": "G3MY77", "url": "https://omabrowser.org/oma/group/G3MY77/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CQY5-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "Magt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPRWFWSVCAIAAVALLLVSKVPSASAQRKKEMVLSEKVSQLMEWANKRPVIRMNGDKFRRLVKAPPRNYSVVVMFTALQLHRQCVVCKQADEEFQILANSWRYSNAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPPKGKPKRADTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRRMMCIAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS", "length": 335 }, "evidence": [ { "id": "G3MY77", "url": "https://omabrowser.org/oma/group/G3MY77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARWRFWCVSVTMVVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS", "length": 335 }, "evidence": [ { "id": "G3MY77", "url": "https://omabrowser.org/oma/group/G3MY77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MY77", "url": "https://www.uniprot.org/uniprotkb/G3MY77" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "G3MY77", "url": "https://www.uniprot.org/uniprotkb/G3MY77" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex B", "id": "GO:0160227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160227", "evidence": [ { "database": "UniProtKB", "id": "G3MY77", "url": "https://www.uniprot.org/uniprotkb/G3MY77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "magnesium ion transmembrane transporter activity", "id": "GO:0015095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015095", "evidence": [ { "database": "UniProtKB", "id": "G3MY77", "url": "https://www.uniprot.org/uniprotkb/G3MY77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "magnesium ion transmembrane transport", "id": "GO:1903830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903830", "evidence": [ { "database": "UniProtKB", "id": "G3MY77", "url": "https://www.uniprot.org/uniprotkb/G3MY77" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "G3MY77", "url": "https://www.uniprot.org/uniprotkb/G3MY77" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "G3MY77", "url": "https://www.uniprot.org/uniprotkb/G3MY77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MY77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 335, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MY77-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MY77" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 215, "end_pos": 217 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6S1J8-1", "uniprot_ac": "F6S1J8", "uniprot_id": "F6S1J8_BOVIN", "mass": { "chemical_mass": 70106.0, "monoisotopic_mass": 70106.0 }, "refseq": {}, "gene_names": [ { "name": "YES1", "type": "recommended", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase", "type": "recommended", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "YES1", "url": "https://www.uniprot.org/uniprotkb/F6S1J8", "locus": { "chromosome": "24", "start_pos": 35592011, "end_pos": 35656733, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001523", "url": "https://www.ensembl.org/id/ENSBTAG00000001523" } ] } } ], "crossref": [ { "id": "F6S1J8", "url": "https://alphafold.ebi.ac.uk/entry/F6S1J8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05069", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05069", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09933", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09933", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12007", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12007", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZL9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZL9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S1J8-1", "url": "https://www.uniprot.org/uniprotkb/F6S1J8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGAGSEGGPRAGRRWSVRPRGGEPGNSLLLKWRAGGRLCRRRCRPAPGTRRWRTGAGAAGLVSARRPLPATLPCCCGDSCERGWSAGLIMGCIKSKENKSPSIKYRPENTPEPVSTGVGHYGGEHAVVAPTSSTKSTSANFSSLSMTPFGGSSAVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL", "length": 632, "header": "tr|F6S1J8-1|F6S1J8_BOVIN Isoform 1 of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=YES1 PE=3 SV=1 CANONICAL=F6S1J8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ7/entry", "sequence": { "sequence": "MGCIKSKENKSPSIKYRPENTPEPVSTGVGHYGGEHAVVAPTSSTKSTSANFSSLSMTPFGGSSAVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL", "length": 497, "header": "tr|A0A3Q1LVZ7-1|A0A3Q1LVZ7_BOVIN Computationally mapped isoform of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=YES1 PE=3 SV=1 CANONICAL=F6S1J8-1" }, "locus": { "chromosome": "24", "start_pos": 35614423, "end_pos": 35595189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070883.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070883.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061363.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061363.2" } ] } }, { "isoform_ac": "A0AAA9RZL9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZL9/entry", "sequence": { "sequence": "MAAHQAPPSLGFSRQEHWSLIMGCIKSKENKSPSIKYRPENTPEPVSTGVGHYGGEHAVVAPTSSTKSTSANFSSLSMTPFGGSSAVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL", "length": 562, "header": "tr|A0AAA9RZL9-1|F6S1J8_BOVIN Computationally mapped isoform of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=YES1 PE=3 SV=1 CANONICAL=F6S1J8-1" }, "locus": { "chromosome": "24", "start_pos": 35619085, "end_pos": 35595189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121264.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121264.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076538.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076538.1" } ] } }, { "isoform_ac": "F6S1J8-1", "url": "https://www.uniprot.org/uniprotkb/F6S1J8/entry", "sequence": { "sequence": "MGGGAGSEGGPRAGRRWSVRPRGGEPGNSLLLKWRAGGRLCRRRCRPAPGTRRWRTGAGAAGLVSARRPLPATLPCCCGDSCERGWSAGLIMGCIKSKENKSPSIKYRPENTPEPVSTGVGHYGGEHAVVAPTSSTKSTSANFSSLSMTPFGGSSAVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL", "length": 632, "header": "tr|F6S1J8-1|F6S1J8_BOVIN Isoform 1 of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=YES1 PE=3 SV=1 CANONICAL=F6S1J8-1" }, "locus": { "chromosome": "24", "start_pos": 35656534, "end_pos": 35595189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001995.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001995.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001995.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001995.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 133, "start_aa": "Thr", "end_pos": 133, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr133", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" }, { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6S1J8", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MWN2-1", "A0AAF6DMB3-1", "E1BI01-1", "A0AAA9TQL1-1", "F1MQH2-1", "F1N781-1", "F6QXU6-1", "A0A3Q1MKW9-1", "A0A3Q1M0U5-1", "F6S1J8-1", "A5D791-1", "F1N664-1", "E1BMP9-1", "F1MS00-1", "P43481-1", "A0A3Q1LR28-1", "A0A3Q1LVP1-1", "Q06807-1", "A0AAA9TD48-1", "Q5E9X2-1", "Q05688-1", "Q17R13-1", "E1BG90-1", "Q0VBZ0-1", "F1N758-1", "A0A3Q1LTC6-1", 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"uniprot_ac": "A0AAA9SVL9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] } ] }, { "uniprot_ac": "A0AAA9TMY2", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] } ] }, { "uniprot_ac": "A0AAA9TQL1", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "E1B6X6", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] } ] }, { "uniprot_ac": "E1B9H4", "gene_name": "PKDCC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BER5", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6H6", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] } ] }, { "uniprot_ac": "F1N6J0", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N780", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] } ] }, { "uniprot_ac": "F1N781", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] } ] }, { "uniprot_ac": "F6QXU6", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] } ] }, { "uniprot_ac": "F6S1J8", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] } ] }, { "uniprot_ac": "G1K218", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] } ] }, { "uniprot_ac": "G3X680", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": "Q05688", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] } ] }, { "uniprot_ac": "Q06805", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] } ] }, { "uniprot_ac": "Q06807", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q769I5", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q769I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q769I5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q769I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q769I5" } ] } ] }, { "uniprot_ac": "Z4YHD9", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Z4YHD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YHD9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Z4YHD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YHD9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 619, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 344, "start_aa": "Trp", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 241, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.10.2", "ec_name": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.10.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.10.2" }, { "id": "2.7.10.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.10.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 133 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 386, "end_pos": 388 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"Bos taurus [9913]" } ], "gene": [ { "name": "LCK", "url": "https://www.uniprot.org/uniprotkb/F6QXU6", "locus": { "chromosome": "2", "start_pos": 121262594, "end_pos": 121283528, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012695", "url": "https://www.ensembl.org/id/ENSBTAG00000012695" } ] } } ], "crossref": [ { "id": "F6QXU6", "url": "https://alphafold.ebi.ac.uk/entry/F6QXU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10362", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10362", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12005", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12005", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S0F1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0F1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGR4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QXU6-1", "url": "https://www.uniprot.org/uniprotkb/F6QXU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKHYKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENDMLLDPYLGEKGLGAFPWGNLGQQLLLMSTGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKERPEERPTFDYLRSVLEDFFTATEGQYQPQP", "length": 539, "header": "tr|F6QXU6-1|F6QXU6_BOVIN Isoform 1 of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=LCK PE=3 SV=1 CANONICAL=F6QXU6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0F1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0F1/entry", "sequence": { "sequence": "MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKHYKIRNLDKGGFYISPRVTFPGLHELVRHYMRYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKERPEERPTFDYLRSVLEDFFTATEGQYQPQP", "length": 458, "header": "tr|A0AAA9S0F1-1|F6QXU6_BOVIN Computationally mapped isoform of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=LCK PE=3 SV=1 CANONICAL=F6QXU6-1" }, "locus": { "chromosome": "2", "start_pos": 121270996, "end_pos": 121263049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119736.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119736.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078438.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078438.1" } ] } }, { "isoform_ac": "A0AAA9SGR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGR4/entry", "sequence": { "sequence": "MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKHYKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGTANIALPSLPSMKTKIPLDWCSHHTCCQISS", "length": 474, "header": "tr|A0AAA9SGR4-1|F6QXU6_BOVIN Computationally mapped isoform of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=LCK PE=3 SV=1 CANONICAL=F6QXU6-1" }, "locus": { "chromosome": "2", "start_pos": 121270996, "end_pos": 121263319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088261.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088261.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081690.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081690.1" } ] } }, { "isoform_ac": "F6QXU6-1", "url": "https://www.uniprot.org/uniprotkb/F6QXU6/entry", "sequence": { "sequence": "MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKHYKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENDMLLDPYLGEKGLGAFPWGNLGQQLLLMSTGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKERPEERPTFDYLRSVLEDFFTATEGQYQPQP", "length": 539, "header": "tr|F6QXU6-1|F6QXU6_BOVIN Isoform 1 of Tyrosine-protein kinase OS=Bos taurus OX=9913 GN=LCK PE=3 SV=1 CANONICAL=F6QXU6-1" }, "locus": { "chromosome": "2", "start_pos": 121270996, "end_pos": 121263049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038070.5", "url": "https://www.ensembl.org/id/ENSBTAT00000038070.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037887.4", "url": "https://www.ensembl.org/id/ENSBTAP00000037887.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 16, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "CD4 receptor binding", "id": "GO:0042609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042609", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "T cell receptor binding", "id": "GO:0042608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042608", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "protein antigen binding", "id": "GO:1990405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990405", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "phospholipase activator activity", "id": "GO:0016004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016004", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "CD8 receptor binding", "id": "GO:0042610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042610", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "positive regulation of multicellular organismal process", "id": "GO:0051240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051240", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "regulation of developmental process", "id": "GO:0050793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050793", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "cell development", "id": "GO:0048468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "Fc-gamma receptor signaling pathway", "id": "GO:0038094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038094", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "positive regulation of intrinsic apoptotic signaling pathway", "id": "GO:2001244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001244", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "positive regulation of heterotypic cell-cell adhesion", "id": "GO:0034116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034116", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "NK T cell activation", "id": "GO:0051132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051132", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" }, { "name": "CD27 signaling pathway", "id": "GO:0160162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160162", "evidence": [ { "database": "UniProtKB", "id": "F6QXU6", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MWN2-1", "A0AAF6DMB3-1", "E1BI01-1", "A0AAA9TQL1-1", "F1MQH2-1", "F1N781-1", "F6QXU6-1", "A0A3Q1MKW9-1", "A0A3Q1M0U5-1", "F6S1J8-1", "A5D791-1", "F1N664-1", "E1BMP9-1", "F1MS00-1", "P43481-1", "A0A3Q1LR28-1", "A0A3Q1LVP1-1", "Q06807-1", "A0AAA9TD48-1", "Q5E9X2-1", "Q05688-1", "Q17R13-1", "E1BG90-1", "Q0VBZ0-1", "F1N758-1", "A0A3Q1LTC6-1", "A0A3Q1LNU2-1", "F1N1Q0-1", "A0A3Q1MHB0-1", "A0AAA9SN20-1", "A0AAA9TMY2-1", "A0A3Q1LI98-1", "E1BJ31-1", "A0A3Q1LRR9-1", "F1MX49-1", "A0A3Q1MHG9-1", "A0JNB0-1", "E1BER5-1", "E1BIM8-1", "E1BNE0-1", "A0A3Q1LT44-1", "A0A3Q1MJG0-1", "F1MII5-1", "F1N0D3-1", "F1N261-1", "F1N759-1", "F1N780-1", "F1MC14-1", "F1N3R6-1", "A0ABI0P1V8-1", "A0A3Q1LUE0-1", "F1MFH7-1", "F1MNW2-1", "A0AAA9SPC9-1", "F1N381-1", "F1MS29-1", "G1K218-1", "Q4TVR5-1", "A0AAA9SXH6-1", "E1BJS9-1", "A0AAA9SBR4-1", "F1MKR1-1", "F1MN51-1", "E1BCZ6-1", "E1BEL4-1", "F1MCX4-1", "F1N6J0-1", "Q3SZJ2-1", "Q769I5-1", "Z4YHD9-1", "Q06805-1", "Q3SX21-1", "A0A3Q1MAM7-1", "E1BPB5-1", "A0A3Q1MF99-1", "A0AAA9SA57-1", "A0AAA9TAT1-1", "A0AAA9THG2-1", "F1MC23-1", "A0AAA9SVL9-1", "F1MRU0-1", "A0AAA9T042-1", "E1BKP7-1", "E1BNA8-1", "F1ML02-1", "E1BPI3-1", "A0AAA9SW95-1", "G3X680-1", "A0AAA9TRY4-1", "A0A3Q1MEZ6-1", "E1B9H4-1", "E1B6X6-1", "E1B9Q2-1", "E1BPP1-1", "F1N6H6-1", "A0ABI0NRQ5-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LI98", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRR9", "gene_name": "TYRO3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR9" } ] } ] }, { "uniprot_ac": "A0A3Q1LT44", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LUE0", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] } ] }, { "uniprot_ac": "A0A3Q1LVP1", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVP1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1LVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVP1" } ] } ] }, { "uniprot_ac": "A0A3Q1M0U5", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0U5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1M0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0U5" } ] } ] }, { "uniprot_ac": "A0A3Q1MAM7", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MAM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MAM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAM7" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MF99", "gene_name": "TXK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF99" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1MF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF99" } ] } ] }, { "uniprot_ac": "A0A3Q1MHB0", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHB0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHB0" } ] } ] }, { "uniprot_ac": "A0A3Q1MHG9", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] } ] }, { "uniprot_ac": "A0A3Q1MJG0", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJG0" } ] } ] }, { "uniprot_ac": "A0A3Q1MKW9", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKW9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKW9" } ] } ] }, { "uniprot_ac": "A0AAA9SA57", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] } ] }, { "uniprot_ac": "A0AAA9SBR4", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] } ] }, { "uniprot_ac": "A0AAA9SN20", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] } ] }, { "uniprot_ac": "A0AAA9SPC9", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] } ] }, { "uniprot_ac": "A0AAA9SVL9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] } ] }, { "uniprot_ac": "A0AAA9TMY2", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] } ] }, { "uniprot_ac": "A0AAA9TQL1", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "E1B6X6", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] } ] }, { "uniprot_ac": "E1B9H4", "gene_name": "PKDCC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BER5", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", 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"https://www.uniprot.org/uniprotkb/F6QYF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F6QYF9", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "F6QYF9", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F6QYF9", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ], "pmid": "" }, { "name": "cGAS/STING signaling pathway", "id": "GO:0140896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140896", "evidence": [ { "database": "UniProtKB", "id": "F6QYF9", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", 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"activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] } ] }, { "uniprot_ac": "A0A3Q1M7R9", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDD8", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] } ] }, { "uniprot_ac": "A0A3Q1MR43", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] } ] }, { "uniprot_ac": "A0A3Q1NMG4", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] } ] }, { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] } ] }, { "uniprot_ac": "A0AAA9S5G9", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] } ] }, { "uniprot_ac": "A0AAA9S7V9", "gene_name": "RECQL4", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9SPF3", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": 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"uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { 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2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": 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"ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] } ] }, { "uniprot_ac": "Q0V8B7", "gene_name": "MCM5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] } ] }, { "uniprot_ac": "Q0V8H6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP + n phosphate + unwound RNA.", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] } ] }, { "uniprot_ac": "Q0VCX2", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": 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{ "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] } ] }, { "uniprot_ac": "Q29S22", "gene_name": "DDX47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] } ] }, { "uniprot_ac": "Q2HJF8", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2HJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF8" } ] } ] }, { "uniprot_ac": "Q2KIZ8", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] } ] }, { "uniprot_ac": "Q2NL08", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] } ] }, { "uniprot_ac": "Q2NL22", "gene_name": "EIF4A3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] } ] }, { "uniprot_ac": "Q2T9X2", "gene_name": "CCT4", "activity": [ { "ec_number": 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"Protein Classification" ] }, { "id": "PTHR24056:SF171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S1Z1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGI9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGI9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVY2-1", "url": "https://www.uniprot.org/uniprotkb/F6QVY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIEDSQYGLGIRENVSHESLEADGVPLQVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSELPIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG", "length": 367, "header": "tr|F6QVY2-1|F6QVY2_BOVIN Isoform 1 of Cyclin-dependent kinase 20 OS=Bos taurus OX=9913 GN=CDK20 PE=3 SV=1 CANONICAL=F6QVY2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S1Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Z1/entry", "sequence": { "sequence": "MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRLYTHQVATRAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSELPIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG", "length": 325, "header": "tr|A0AAA9S1Z1-1|F6QVY2_BOVIN Computationally mapped isoform of Cyclin-dependent kinase 20 OS=Bos taurus OX=9913 GN=CDK20 PE=3 SV=1 CANONICAL=F6QVY2-1" }, "locus": { "chromosome": "8", "start_pos": 90066900, "end_pos": 90058957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089358.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089358.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079056.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079056.1" } ] } }, { "isoform_ac": "A0AAA9SGI9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGI9/entry", "sequence": { "sequence": "MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHANNIVHREITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSELPIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG", "length": 243, "header": "tr|A0AAA9SGI9-1|F6QVY2_BOVIN Computationally mapped isoform of Cyclin-dependent kinase 20 OS=Bos taurus OX=9913 GN=CDK20 PE=3 SV=1 CANONICAL=F6QVY2-1" }, "locus": { "chromosome": "8", "start_pos": 90066900, "end_pos": 90058957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113215.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113215.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082805.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082805.1" } ] } }, { "isoform_ac": "F6QVY2-1", "url": "https://www.uniprot.org/uniprotkb/F6QVY2/entry", "sequence": { "sequence": "MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIEDSQYGLGIRENVSHESLEADGVPLQVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSELPIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG", "length": 367, "header": "tr|F6QVY2-1|F6QVY2_BOVIN Isoform 1 of Cyclin-dependent kinase 20 OS=Bos taurus OX=9913 GN=CDK20 PE=3 SV=1 CANONICAL=F6QVY2-1" }, "locus": { "chromosome": "8", "start_pos": 90066900, "end_pos": 90058957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020188.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020188.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020188.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020188.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F6QVY2", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] } ] }, { "uniprot_ac": "A0A3Q1M4X3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] } ] }, { "uniprot_ac": "A0A3Q1M5T5", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 310, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.22", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.22", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.22" }, { "id": "2.7.11.22", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.22" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RJ62-1", "uniprot_ac": "F6RJ62", "uniprot_id": "F6RJ62_BOVIN", "mass": { "chemical_mass": 69478.0, "monoisotopic_mass": 69478.0 }, "refseq": {}, "gene_names": [ { "name": "GALNT18", "type": "recommended", "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ] } ], "protein_names": [ { "name": "Polypeptide N-acetylgalactosaminyltransferase", "type": "recommended", "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62/entry#names_and_taxonomy" } ] }, { "name": "Protein-UDP acetylgalactosaminyltransferase", "type": "synonym", "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GALNT18", "url": "https://www.uniprot.org/uniprotkb/F6RJ62", "locus": { "chromosome": "15", "start_pos": 41420058, "end_pos": 41064404, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002914", "url": "https://www.ensembl.org/id/ENSBTAG00000002914" } ] } } ], "crossref": [ { "id": "F6RJ62", "url": "https://alphafold.ebi.ac.uk/entry/F6RJ62", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002914", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002914", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23475", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23475", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614203", "url": "https://www.ncbi.nlm.nih.gov/gene/614203", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WHRGNKS", "url": "https://omabrowser.org/oma/group/WHRGNKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RJ62", "url": "https://www.orthodb.org/?gene=F6RJ62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S622", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S622", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S622-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S622-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S808", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S808", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S808-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S808-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJ62-1", "url": "https://www.uniprot.org/uniprotkb/F6RJ62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDGLPEVSIVFIFVNEALSVLLRSIHSAIERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKSDLCLDQGPETENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYARAKRMKLHWQFSQGGPIQNRKSKRCLELQENSEAEFGFQLVLQRCSGQHWSITNVLRSLAS", "length": 607, "header": "tr|F6RJ62-1|F6RJ62_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT18 PE=3 SV=1 CANONICAL=F6RJ62-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S622-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S622/entry", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDGLPEVSIVFIFVNEALSVLLRSIHSAIERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKSDLCLDQGPETENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYARAKRMKLHWQFSQLASSQDYPQASPAAAACLLLTAVPESSQPAGLSLSGLLV", "length": 598, "header": "tr|A0AAA9S622-1|F6RJ62_BOVIN Computationally mapped isoform of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT18 PE=3 SV=1 CANONICAL=F6RJ62-1" }, "locus": { "chromosome": "15", "start_pos": 41414495, "end_pos": 41064592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112359.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112359.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078759.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078759.1" } ] } }, { "isoform_ac": "A0AAA9S808-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S808/entry", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDGLPEVSIVFIFVNEALSVLLRSIHSAIERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKSDLCLDQGPETENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYARAKRMKLHWQFSQRRILPRWSGPGKRAQPGGLSQLAGENERTSLPHLFQHRDPRGLSEPLPGGPSSLGPSEPEPEGFSLAAPLGPREAPSRTASPSAVWSCRRTAKRSSASSWCCRGARASTGASPTS", "length": 674, "header": "tr|A0AAA9S808-1|F6RJ62_BOVIN Computationally mapped isoform of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT18 PE=3 SV=1 CANONICAL=F6RJ62-1" }, "locus": { "chromosome": "15", "start_pos": 41419699, "end_pos": 41064592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120977.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120977.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082175.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082175.1" } ] } }, { "isoform_ac": "F6RJ62-1", "url": "https://www.uniprot.org/uniprotkb/F6RJ62/entry", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDGLPEVSIVFIFVNEALSVLLRSIHSAIERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKSDLCLDQGPETENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYARAKRMKLHWQFSQGGPIQNRKSKRCLELQENSEAEFGFQLVLQRCSGQHWSITNVLRSLAS", "length": 607, "header": "tr|F6RJ62-1|F6RJ62_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=GALNT18 PE=3 SV=1 CANONICAL=F6RJ62-1" }, "locus": { "chromosome": "15", "start_pos": 41419716, "end_pos": 41064592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003784.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003784.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003784.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003784.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XFR5-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "Galnt18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCFDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGVLSPTIDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKRCLELQENSDMEFGFQLVLQKCSGQHWTITNVLRSLVS", "length": 622 }, "evidence": [ { "id": "F6RJ62", "url": "https://omabrowser.org/oma/group/F6RJ62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F4H6-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "galnt18b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MACTRRTKTLVSTCVILSGMTNIVCLLYVGWVTNYIANVYIKVPVPVPAKKLEGDRKGETLRIIERLDRLENVVNQHIQESPLKGDDNQVDRSFADSSLFNHWGQDLGPESRRVALKMFQYYGYNGYLSDRLSMDRAIPDYRPDGCKNMSYPSNLPQVSIVFIFVNEALSVILRSIHSVMNRTPSHLLKEIILVDDNSNNDELKEKLQDFVKETNAKQPGFIKVVRHSRQEGLIRSRVSGWRAASAPVVALFDAHVEFNIGWAEPILQRIKEDRTRIISPSFDNIKYDTFEIEEYPLSAQGFDWELWCRYLNPPKSWWNLNNSTAPIRSPALIGCFVVDRLYFAEIGLLDEGMEIYGGENVELGVRVWQCGGSVEVLPCARIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDIAERKALRKKLQCKTFRWYLVNIYPEMRMYTDTVAYGVLRNSLKTDLCLDQGPDTDNIPILYLCHGMTPQNVYYTSTQQLFVGILSPTVDDDDNKCLVDVNGRPRLIECSYAVAKRMKLHWRFTQGGSIQNTKSKRCLELVENNDNEFGFQLTLQKCTGQNWTITNMLPGSTL", "length": 609 }, "evidence": [ { "id": "F6RJ62", "url": "https://omabrowser.org/oma/group/F6RJ62/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S6W6-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase", "gene_name": "GALNT18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQDLSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMKRTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGPIQNRKSKRCLELQENSDAEFGFQLVLQRCSGQHWSITNVLRSLAS", "length": 607 }, "evidence": [ { "id": "F6RJ62", "url": "https://omabrowser.org/oma/group/F6RJ62/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6P9A2-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 18", "gene_name": "GALNT18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPAPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPPHLLKEIILVDDNSSNEELKEKLTEYVDKVNSQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFQEIGLLDEGMEVYGGENVELGIRVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIMYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGPIQNRKSKRCLELQENSDLEFGFQLVLQKCSGQHWSITNVLRSLAS", "length": 607 }, "evidence": [ { "id": "F6RJ62", "url": "https://omabrowser.org/oma/group/F6RJ62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1B9-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 18", "gene_name": "Galnt18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVCTRKTKTLVSTCVILSGMTNIICLLYVGWVTNYIASVYVRGQEPVPDKKLEEDKGDTLKIIERLDHLENVIKQHIQEAPAKPEEAEAEPFTDSSLFAHWGQELSPEGRRVALKQFQYYGYNAYLSDRLPLDRPLPDLRPSGCRNLSFPDSLPEVSIVFIFVNEALSVLLRSIHSAMERTPSHLLKEIILVDDNSSNEELKEKLTEYVDKVNGQKPGFIKVVRHSKQEGLIRSRVSGWRAATAPVVALFDAHVEFNVGWAEPVLTRIKENRKRIISPSFDNIKYDNFEIEEYPLAAQGFDWELWCRYLNPPKAWWKLENSTAPIRSPALIGCFIVDRQYFEEIGLLDEGMEVYGGENVELGIRVSEISHTGLSSAPMMVWQCGGSVEVLPCSRIAHIERAHKPYTEDLTAHVRRNALRVAEVWMDEFKSHVYMAWNIPQEDSGIDIGDITARKALRKQLQCKTFRWYLVSVYPEMRMYSDIIAYGVLQNSLKTDLCLDQGPDTENVPIVYICHGMTPQNVYYTSSQQIHVGILSPTVDDDDNRCLVDVNSRPRLIECSYAKAKRMKLHWQFSQGGSIQNRKSKRCLELQENSDMEFGFQLVLQKCSGQHWTITNVLRSLVS", "length": 622 }, "evidence": [ { "id": "F6RJ62", "url": "https://omabrowser.org/oma/group/F6RJ62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "F6RJ62", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-913675", "name": "GALNTs transfer GalNAc to Mucins to form Tn antigens", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-9942384" ], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M986-1", "Q07537-1", "E1BDW8-1", "E1BHN6-1", "A0AAA9T153-1", "F1N554-1", "F6QA59-1", "F6RJ62-1", "A0AAA9S1Y7-1", "E1BPR6-1", "E1B9U7-1", "A0AAA9S5W3-1", "E1BKQ9-1" ], "evidence": [ { "id": "R-BTA-913675", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913675" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9942384", "participant_name": "UDP-GalNAc [Golgi lumen]", "crossref": [ { "id": "67138", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551132", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M986", "gene_name": "GALNT2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A3Q1M986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M986" } ] } ] }, { "uniprot_ac": "A0AAA9S1Y7", "gene_name": "GALNT14", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9S1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1Y7" } ] } ] }, { "uniprot_ac": "A0AAA9S5W3", "gene_name": "GALNT3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9S5W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W3" } ] } ] }, { "uniprot_ac": "A0AAA9T153", "gene_name": "GALNT7", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0AAA9T153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T153" } ] } ] }, { "uniprot_ac": "E1B9U7", "gene_name": "GALNT17", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1B9U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9U7" } ] } ] }, { "uniprot_ac": "E1BDW8", "gene_name": "GALNT11", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BDW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDW8" } ] } ] }, { "uniprot_ac": "E1BHN6", "gene_name": "GALNT15", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BHN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHN6" } ] } ] }, { "uniprot_ac": "E1BKQ9", "gene_name": "GALNT5", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKQ9" } ] } ] }, { "uniprot_ac": "E1BPR6", "gene_name": "GALNT9", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "E1BPR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPR6" } ] } ] }, { "uniprot_ac": "F1N554", "gene_name": "GALNT10", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F1N554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N554" } ] } ] }, { "uniprot_ac": "F6QA59", "gene_name": "GALNT8", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6QA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QA59" } ] } ] }, { "uniprot_ac": "F6RJ62", "gene_name": "GALNT18", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" } ] } ] }, { "uniprot_ac": "Q07537", "gene_name": "GALNT1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] }, { "ec_number": "2.4.1.41", "activity": "L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] }, { "ec_number": "2.4.1.41", "activity": "", "evidence": [ { "id": "Q07537", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07537" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RJ62-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 607, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RJ62-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RJ62" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ62" }, { "id": "SM00458", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ricin B lectin", "eco_id": "ECO_0000259", "start_pos": 470, "end_pos": 599, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00027JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00031MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00032MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00033MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034UM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00035MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00036MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00037MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00038MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00039MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00040MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00041IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00041MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00042MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00043MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00044MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00063MO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00069YC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00079IK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00094SE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00112IO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00139WK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00140UB", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00140YZ", "type": "O-linked", "subtype": "Core 2" }, { 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"https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VTQWTWY", "url": "https://omabrowser.org/oma/group/VTQWTWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RFP6", "url": "https://www.orthodb.org/?gene=F6RFP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S8Z2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRF6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRF6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6C7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6C7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RFP6", "url": "https://www.uniprot.org/uniprotkb/F6RFP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RFP6-1", "url": "https://www.uniprot.org/uniprotkb/F6RFP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPCACAGGRRLTVHAPRPQRCLRARARRLSGSYSAAGSGCAGTAGRRDMAAGQIAVLGLVLLSAQGGFGAGSRIWTNIDNDGSKTRLTCALNHSATEIVGHRWVKGGKVLKEDALPDLKTEYEVDSEDRSGQYSCIFLPEHAGRTDLEVKGPPSIKAVKKSEHATEGETVILVCKSDSFPPVTNWLWYKESESGDQVITNSTQSKFFVVSSESRTELHIPNVDLKEDPGKYVCNGTNLEGTSQAAITLRVRNRFAALWPFLGIVAEVLVLVTIIFIYEKRRKPDEVLDDEDIGSAPLKSSGNPLNDKDKDKNVRQRNSS", "length": 320, "header": "tr|F6RFP6-1|F6RFP6_BOVIN Isoform 1 of Basigin OS=Bos taurus OX=9913 GN=BSG PE=1 SV=1 CANONICAL=F6RFP6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S8Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8Z2/entry", "sequence": { "sequence": "MAAGQIAVLGLVLLSAQGGFGAGSRIWTNIDNDGSKTRLTCALNHSATEIVGHRWVKGGKVLKEDALPDLKTEYEVDSEDRSGQYSCIFLPEHAGRTDLEVKGPPSIKAVKKSEHATEGETVILVCKSDSFPPVTNWLWYKESESGDQVITNSTQSKFFVVSSESRTELHIPNVDLKEDPGKYVCNGTNLEGTSQAAITLRVRNRFAALWPFLGIVAEVLVLVTIIFIYEKRRKPDEVLDGVKAPAPGPSLRLLGWAGLEPGPCPLWKVTGRSQAVCRAKRPAVWSQCCQVTAGLTTWRP", "length": 300, "header": "tr|A0AAA9S8Z2-1|F6RFP6_BOVIN Computationally mapped isoform of Basigin OS=Bos taurus OX=9913 GN=BSG PE=1 SV=2 CANONICAL=F6RFP6-1" }, "locus": { "chromosome": "7", "start_pos": 43208504, "end_pos": 43201709, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104610.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104610.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080389.2", "url": "https://www.ensembl.org/id/ENSBTAP00000080389.2" } ] } }, { "isoform_ac": "A0AAA9SSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSZ2/entry", "sequence": { "sequence": "MRPCACAGGRRLTVHAPRPQRCLRARARRLSGSYSAAGSGCAGTAGRRDMAAGQIAVLGLVLLSAQGGFGAGSRIWTNIDNDGSKTRLTCALNHSATEIVGHRWVKGGKVLKEDALPDLKTEYEVDSEDRSGQYSCIFLPEHAGRTDLEVKGPPSIKAVKKSEHATEGETVILVCKSDSFPPVTNWLWYKESESGDQVITNSTQSKFFVVSSESRTELHIPNVDLKEDPGKYVCNGTNLEGTSQAAITLRVRNRFAALWPFLGIVAEVLVLVTIIFIYEKRRKPDEVLDGEPDSSAPRKSSGNPLNDKDKDKNVRQRNSS", "length": 320, "header": "tr|A0AAA9SSZ2-1|F6RFP6_BOVIN Computationally mapped isoform of Basigin OS=Bos taurus OX=9913 GN=BSG PE=1 SV=2 CANONICAL=F6RFP6-1" }, "locus": { "chromosome": "7", "start_pos": 43207922, "end_pos": 43201562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103830.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103830.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089531.2", "url": "https://www.ensembl.org/id/ENSBTAP00000089531.2" } ] } }, { "isoform_ac": "A0ABI0NRF6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRF6/entry", "sequence": { "sequence": "MAAGQIAVLGLVLLSAQGGFGAGPPSIKAVKKSEHATEGETVILVCKSDSFPPVTNWLWYKESESGDQVITNSTQSKFFVVSSESRTELHIPNVDLKEDPGKYVCNGTNLEGTSQAAITLRVRNRFAALWPFLGIVAEVLVLVTIIFIYEKRRKPDEVLDDEDIGSAPLKSSGNPLNDKDKDKNVRQRNSS", "length": 191, "header": "tr|A0ABI0NRF6-1|A0ABI0NRF6_BOVIN Computationally mapped isoform of Basigin OS=Bos taurus OX=9913 GN=BSG PE=1 SV=1 CANONICAL=F6RFP6-1" }, "locus": { "chromosome": "7", "start_pos": 43207922, "end_pos": 43201709, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138292.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138292.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106213.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106213.1" } ] } }, { "isoform_ac": "A0ABI0P6C7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6C7/entry", "sequence": { "sequence": "CRGQRLRGDGWTAGYGGRSDRGVGARAAECPGWLRGRIWTNIDNDGSKTRLTCALNHSATEIVGHRWVKGGKVLKEDALPDLKTEYEVDSEDRSGQYSCIFLPEHAGRTDLEVKGPPSIKAVKKSEHATEGETVILVCKSDSFPPVTNWLWYKESESGDQVITNSTQSKFFVVSSESRTELHIPNVDLKEDPGKYVCNGTNLEGTSQAAITLRVRNRFAALWPFLGIVAEVLVLVTIIFIYEKRRKPDEVLDDEDIGSAPLKSSGNPLNDKDKDKNVRQRNSS", "length": 283, "header": "tr|A0ABI0P6C7-1|A0ABI0P6C7_BOVIN Computationally mapped isoform of Basigin OS=Bos taurus OX=9913 GN=BSG PE=1 SV=1 CANONICAL=F6RFP6-1" }, "locus": { "chromosome": "7", "start_pos": 43207922, "end_pos": 43201666, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137568.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137568.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107476.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107476.1" } ] } }, { "isoform_ac": "F6RFP6-1", "url": "https://www.uniprot.org/uniprotkb/F6RFP6/entry", "sequence": { "sequence": "MRPCACAGGRRLTVHAPRPQRCLRARARRLSGSYSAAGSGCAGTAGRRDMAAGQIAVLGLVLLSAQGGFGAGSRIWTNIDNDGSKTRLTCALNHSATEIVGHRWVKGGKVLKEDALPDLKTEYEVDSEDRSGQYSCIFLPEHAGRTDLEVKGPPSIKAVKKSEHATEGETVILVCKSDSFPPVTNWLWYKESESGDQVITNSTQSKFFVVSSESRTELHIPNVDLKEDPGKYVCNGTNLEGTSQAAITLRVRNRFAALWPFLGIVAEVLVLVTIIFIYEKRRKPDEVLDDEDIGSAPLKSSGNPLNDKDKDKNVRQRNSS", "length": 320, "header": "tr|F6RFP6-1|F6RFP6_BOVIN Isoform 1 of Basigin OS=Bos taurus OX=9913 GN=BSG PE=1 SV=1 CANONICAL=F6RFP6-1" }, "locus": { "chromosome": "7", "start_pos": 43207922, "end_pos": 43201562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000040082.7", "url": "https://www.ensembl.org/id/ENSBTAT00000040082.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039862.5", "url": "https://www.ensembl.org/id/ENSBTAP00000039862.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F6RFP6", "url": "https://www.uniprot.org/uniprotkb/F6RFP6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RFP6", "url": "https://www.uniprot.org/uniprotkb/F6RFP6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "F6RFP6", "url": "https://www.uniprot.org/uniprotkb/F6RFP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RFP6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RFP6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RFP6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RFP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFP6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 136, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": 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] } ], "protein_names": [ { "name": "Keratin, type I cytoskeletal 10", "type": "recommended", "evidence": [ { "id": "F6R3N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R3N4/entry#names_and_taxonomy" } ] }, { "name": "Cytokeratin-10", "type": "synonym", "evidence": [ { "id": "F6R3N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R3N4/entry#names_and_taxonomy" } ] }, { "name": "Keratin-10", "type": "synonym", "evidence": [ { "id": "F6R3N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R3N4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the establishment of the epidermal barrier on plantar skin. Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SGP7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGP7#function" }, { "database": "UniProtKB", "id": "ARBA00046049", "url": "https://www.uniprot.org/uniprotkb/ARBA00046049#function" }, { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KRT10", "url": "https://www.uniprot.org/uniprotkb/F6R3N4", "locus": { "chromosome": "19", "start_pos": 41008990, "end_pos": 41013543, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020824", "url": "https://www.ensembl.org/id/ENSBTAG00000020824" } ] } } ], "crossref": [ { "id": "F6R3N4", "url": "https://alphafold.ebi.ac.uk/entry/F6R3N4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SGP7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGP7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R3N4-1", "url": "https://www.uniprot.org/uniprotkb/F6R3N4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWDTPSQYIKACHCPWYQALPELNSITMSVRYSSSKQYSSSRSGGGGGGGSSLRISSSKGSLGGGYSSGGFSGGSFSRGSSAGGCFGGSSSIYGGGLGSGFGGGYGSSFGGSYGGSFGGGYGGGGFGGGSFGGGSFGGGLGGGFGDGGLISGNEKITMQNLNDRLASYLDKVRALEESNYELEVKIKEWYEKYGNSRQREPRDYSKYYQTIDDLKNQIFNLTTDNANILIQVDNARLAADDFRLKYENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLTEELAYLKKNHEEEMRDLQNVSTGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEKNRRDAEAWFNEKSKELTTEINSNLEQVSSHKSEITELRRTIQGLEIELQSQLALKQSLEASLAETEGRYCVQLSQIQSQISSLEEQLQQIRAETECQNAEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGSYGGGRGYGGSSGGGGGGYGGGSSSGGYGGGSSSGGGHGGSSGGSYGGGSSSGGGHGGGSSSGGHKSTTTGSVGESSSKGPRY", "length": 553, "header": "tr|F6R3N4-1|F6R3N4_BOVIN Isoform 1 of Keratin, type I cytoskeletal 10 OS=Bos taurus OX=9913 GN=KRT10 PE=3 SV=1 CANONICAL=F6R3N4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SGP7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGP7/entry", "sequence": { "sequence": "MWDTPSQYIKACHCPWYQALPELNSITMSVRYSSSKQYSSSRSGGGGGGGSSLRISSSKGSLGGGYSSGGFSGGSFSRGSSAGGCFGGSSSIYGGGLGSGFGGGYGSSFGGSYGGSFGGGYGGGGFGGGSFGGGSFGDGGLISGNEKITMQNLNDRLASYLDKVRALEESNYELEVKIKEWYEKYGNSRQREPRDYSKYYQTIDDLKNQIFNLTTDNANILIQVDNARLAADDFRLKYENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLTEELAYLKKNHEEEMRDLQNVSTGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEKNRRDAEAWFNEKSKELTTEINSNLEQVSSHKSEITELRRTIQGLEIELQSQLALKQSLEASLAETEGRYCVQLSQIQSQISSLEEQLQQIRAETECQNAEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGSYGGGRGYGGSSGGGGGGYGGGSSSGGYGGGSSSGGGHGGSSGGSYGGGSSSGGGHGGGSSSGGHKSTTTGSVGESSSKGPRY", "length": 545, "header": "tr|A0AAA9SGP7-1|F6R3N4_BOVIN Computationally mapped isoform of Keratin, type I cytoskeletal 10 OS=Bos taurus OX=9913 GN=KRT10 PE=3 SV=1 CANONICAL=F6R3N4-1" }, "locus": { "chromosome": "19", "start_pos": 41013423, "end_pos": 41009359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087607.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087607.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084524.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084524.1" } ] } }, { "isoform_ac": "F6R3N4-1", "url": "https://www.uniprot.org/uniprotkb/F6R3N4/entry", "sequence": { "sequence": "MWDTPSQYIKACHCPWYQALPELNSITMSVRYSSSKQYSSSRSGGGGGGGSSLRISSSKGSLGGGYSSGGFSGGSFSRGSSAGGCFGGSSSIYGGGLGSGFGGGYGSSFGGSYGGSFGGGYGGGGFGGGSFGGGSFGGGLGGGFGDGGLISGNEKITMQNLNDRLASYLDKVRALEESNYELEVKIKEWYEKYGNSRQREPRDYSKYYQTIDDLKNQIFNLTTDNANILIQVDNARLAADDFRLKYENEVTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLTEELAYLKKNHEEEMRDLQNVSTGDVNVEMNAAPGVDLTELLNNMRSQYEQLAEKNRRDAEAWFNEKSKELTTEINSNLEQVSSHKSEITELRRTIQGLEIELQSQLALKQSLEASLAETEGRYCVQLSQIQSQISSLEEQLQQIRAETECQNAEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGSYGGGRGYGGSSGGGGGGYGGGSSSGGYGGGSSSGGGHGGSSGGSYGGGSSSGGGHGGGSSSGGHKSTTTGSVGESSSKGPRY", "length": 553, "header": "tr|F6R3N4-1|F6R3N4_BOVIN Isoform 1 of Keratin, type I cytoskeletal 10 OS=Bos taurus OX=9913 GN=KRT10 PE=3 SV=1 CANONICAL=F6R3N4-1" }, "locus": { "chromosome": "19", "start_pos": 41013423, "end_pos": 41009359, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017140.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017140.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017140.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017140.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" }, { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein heterotetramerization", "id": "GO:0051290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051290", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" }, { "name": "cornification", "id": "GO:0070268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070268", "evidence": [ { "database": "UniProtKB", "id": "F6R3N4", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R3N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R3N4" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 468, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 }, { "start_pos": 304, "end_pos": 306 } ] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXV0-1", "uniprot_ac": "G3MXV0", "uniprot_id": "G3MXV0_BOVIN", "mass": { "chemical_mass": 51120.0, "monoisotopic_mass": 51120.0 }, "refseq": { "ac": "NP_001179791", "name": "peptidyl-prolyl cis-trans isomerase FKBP5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179791" }, "gene_names": [ { "name": "FKBP5", "type": "recommended", "evidence": [ { "id": "G3MXV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ] }, { "name": "FKBP5", "type": "synonym", "evidence": [ { "id": "NP_001179791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179791" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "G3MXV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXV0/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "G3MXV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXV0/entry#names_and_taxonomy" } ] }, { "name": "FK506 binding protein 5", "type": "synonym", "evidence": [ { "id": "NP_001179791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179791" } ] }, { "name": "peptidyl-prolyl cis-trans isomerase FKBP5", "type": "synonym", "evidence": [ { "id": "NP_001179791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179791" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FKBP5", "url": "https://www.uniprot.org/uniprotkb/G3MXV0", "locus": { "chromosome": "23", "start_pos": 9555619, "end_pos": 9677215, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047502", "url": "https://www.ensembl.org/id/ENSBTAG00000047502" } ] } } ], "crossref": [ { "id": "G3MXV0", "url": "https://alphafold.ebi.ac.uk/entry/G3MXV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047502", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047502", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535704", "url": "https://www.ncbi.nlm.nih.gov/gene/535704", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535704", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535704", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QAILTIH", "url": "https://omabrowser.org/oma/group/QAILTIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXV0", "url": "https://www.orthodb.org/?gene=G3MXV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10516", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10516", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10516:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10516:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8939211", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939211", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9909505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9909505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179791", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179791", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SIQ7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEC7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXV0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTDEAAKNNGESPAAAVAEQGEDITSKKDRGVLKIVKRVGNSEETPMIGDKVYVHYKGKLSTGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRIKRKGEGYSNPNEGATVEIHLEGRCGGRTFDCRDVGFIVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEASKTMSKKTLEGVTNEKEIGSPSMDEQKAEGHV", "length": 457, "header": "tr|G3MXV0-1|G3MXV0_BOVIN Isoform 1 of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP5 PE=4 SV=1 CANONICAL=G3MXV0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SIQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIQ7/entry", "sequence": { "sequence": "MIVKRVGNSEETPMIGDKVYVHYKGKLSTGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRIKRKGEGYSNPNEGATVEIHLEGRCGGRTFDCRDVGFIVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEASKTMSKKTLEGVTNEKEIGSPSMDEQKAEGHV", "length": 423, "header": "tr|A0AAA9SIQ7-1|G3MXV0_BOVIN Computationally mapped isoform of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP5 PE=4 SV=1 CANONICAL=G3MXV0-1" }, "locus": { "chromosome": "23", "start_pos": 9672053, "end_pos": 9557826, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119483.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119483.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085217.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085217.1" } ] } }, { "isoform_ac": "A0AAA9TEC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEC7/entry", "sequence": { "sequence": "MTTDEAAKNNGESPAAAVAEQGEDITSKKDRGVLKIVKRVGNSEETPMIGDKVYVHYKGKLSTGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRIKRKGEGYSNPNEGATVEIHLEGRCGGRTFDCRDVGFIVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRPKNPGRWIPKKNWSRLPLSKRRGLCTSRYVSLCTILSISKNLLNYQ", "length": 268, "header": "tr|A0AAA9TEC7-1|G3MXV0_BOVIN Computationally mapped isoform of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP5 PE=4 SV=1 CANONICAL=G3MXV0-1" }, "locus": { "chromosome": "23", "start_pos": 9627569, "end_pos": 9565504, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112204.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112204.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096964.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096964.1" } ] } }, { "isoform_ac": "G3MXV0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXV0/entry", "sequence": { "sequence": "MTTDEAAKNNGESPAAAVAEQGEDITSKKDRGVLKIVKRVGNSEETPMIGDKVYVHYKGKLSTGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRIKRKGEGYSNPNEGATVEIHLEGRCGGRTFDCRDVGFIVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEASKTMSKKTLEGVTNEKEIGSPSMDEQKAEGHV", "length": 457, "header": "tr|G3MXV0-1|G3MXV0_BOVIN Isoform 1 of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP5 PE=4 SV=1 CANONICAL=G3MXV0-1" }, "locus": { "chromosome": "23", "start_pos": 9627569, "end_pos": 9557826, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064387.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064387.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054371.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054371.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:535704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535704", "resource": "KEGG Pathway" }, { "id": "R-BTA-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-BTA-8939211", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939211", "resource": "Reactome", "description": "ESR-mediated signaling" }, { "id": "R-BTA-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HZU7-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "Fkbp5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTDEGTSNNGENPAATVVEQGEDITTKKDRGVLKIVKRVGTSEETPMIGDKVYVHYKGKLSNGKKFDSSRDRNEPFVFSLGKGQVIKAWDIGVSTMKKGEVCHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDSGIIRRIKRKGEGYSNPNEGATVEVHLEGCCGGRMFDCRDVVFIVGEGEDHDIPIGIDKALEKMQREEQCVLYLGPRYGFGEAGKPKFGIEPNAELMYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSDKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLAVNPQNKAARLQISMCQKKAKEHNERDRRVYANMFTKFAERDAKEAASKAMSKKTVEGEACKRSERQAMEEGKAEGHV", "length": 456 }, "evidence": [ { "id": "G3MXV0", "url": "https://omabrowser.org/oma/group/G3MXV0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q13451-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "gene_name": "FKBP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV", "length": 457 }, "evidence": [ { "id": "G3MXV0", "url": "https://omabrowser.org/oma/group/G3MXV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64378-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "gene_name": "Fkbp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTDEGTSNNGENPAATMTEQGEDITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLFEDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDRRVYANMFKKFAERDAKEEASKAGSKKAVEGAAGKQHESQAMEEGKAKGHV", "length": 456 }, "evidence": [ { "id": "G3MXV0", "url": "https://omabrowser.org/oma/group/G3MXV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "G3MXV0", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M4A4-1", "P18203-1", "Q5BIN5-1", "A6QPY8-1", "F1N4S5-1", "F1N6W2-1", "G3X8B1-1", "A0A3Q1LI03-1", "A0AAA9TG77-1", "F1MNW5-1", "E1B9G4-1", "G3MXV0-1", "Q2KJC8-1", "A0AAF6YJC8-1", "A0AAF6YJR2-1", "P26882-1", "F6RD06-1", "Q32PA9-1", "Q0P5D0-1", "Q2KJ44-1", "Q2HJ89-1", "Q08E11-1", "Q9TRY0-1", "A0A3Q1LK42-1", "A4FV72-1", "P26884-1", "P30404-1", "P62935-1", "P68107-1", "Q29RZ2-1", "P80311-1", "A0AAA9RV00-1", "F1MU79-1", "A0A3Q1LJJ1-1", "Q5E992-1", "Q2YDL5-1", "A0AAA9U018-1", "A0ABI0NKM5-1", "A0ABI0NMT7-1", "A0A3Q1LSB7-1" ], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-BTA-5618073", "name": "FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-BTA-5618108" ], "output_participant_list": [ "R-BTA-5618096" ], "enzyme_list": [ "F1MU79-1", "G3MXV0-1", "Q3ZBF7-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-5618073", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5618073" } ] }, { "id": "R-BTA-5618098", "name": "p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-BTA-443857" ], "enzyme_list": [ "P19120-1", "G3MXV0-1", "Q3ZBF7-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-5618098", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5618098" } ] }, { "id": "R-BTA-5618105", "name": "FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19120-1", "G3MXV0-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-5618105", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5618105" } ] }, { "id": "R-BTA-8939203", "name": "HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26882-1", "F1MU79-1", "F1N719-1", "G3MXV0-1", "Q3ZBF7-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-8939203", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939203" } ] }, { "id": "R-BTA-8939204", "name": "ESTG binds ESR1:chaperone complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26882-1", "F1MU79-1", "F1N719-1", "G3MXV0-1", "Q3ZBF7-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-8939204", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939204" } ] }, { "id": "R-BTA-9032751", "name": "Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26882-1", "F1MU79-1", "F1N719-1", "P46196-1", "G3MXV0-1", "Q3ZBF7-1", "E1B8P9-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-9032751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9032751" } ] }, { "id": "R-BTA-9709547", "name": "ESTG binds ESR2:chaperone complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26882-1", "F1MU79-1", "F1N719-1", "G3MXV0-1", "Q3ZBF7-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-9709547", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9709547" } ] }, { "id": "R-BTA-9716913", "name": "ESR1 binds ESR1 antagonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26882-1", "F1MU79-1", "F1N719-1", "G3MXV0-1", "Q3ZBF7-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-9716913", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9716913" } ] }, { "id": "R-BTA-9716947", "name": "ESR1 binds ESR1 agonists", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26882-1", "F1MU79-1", "F1N719-1", "G3MXV0-1", "Q3ZBF7-1", "Q76LV2-1" ], "evidence": [ { "id": "R-BTA-9716947", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9716947" } ] }, { "id": "R-BTA-9909510", "name": "FKBP5 binds CHUK:IKBKB:IKBKG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95KV1-1", "Q95KV0-1", "G3MXV0-1" ], "evidence": [ { "id": "R-BTA-9909510", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9909510" } ] }, { "id": "R-BTA-9909519", "name": "IFI44, IFI44L binds FKBP5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MXV0-1" ], "evidence": [ { "id": "R-BTA-9909519", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9909519" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-443857", "participant_name": "STIP1 [cytosol]", "crossref": [ { "id": "NP_001030569.1", "database": "RefSeq", "url": "" }, { "id": "Q3ZBZ8", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-BTA-5618096", "participant_name": "FKBP5 [cytosol]", "crossref": [ { "id": "ENSBTAT00000064387", "database": "ENSEMBL", "url": "" }, { "id": "XP_059736378.1", "database": "RefSeq", "url": "" }, { "id": "29024", "database": "VGNC", "url": "" }, { "id": "ENSBTAG00000047502", "database": "ENSEMBL", "url": "" }, { "id": "XP_005223406.1", "database": "RefSeq", "url": "" }, { "id": "G3MXV0", "database": "UniProt", "url": "" }, { "id": "XP_005223405.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAP00000054371", "database": "ENSEMBL", "url": "" }, { "id": "NP_001179791.1", "database": "RefSeq", "url": "" }, { "id": "XP_024839427.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-5618108", "participant_name": "FKBP4 [cytosol]", "crossref": [ { "id": "F1MU79", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000007605", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000009998", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000009998", "database": "ENSEMBL", "url": "" }, { "id": "29023", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LI03", "gene_name": "FKBP11", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI03" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI03" } ] } ] }, { "uniprot_ac": "A0A3Q1LJJ1", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ1" } ] } ] }, { "uniprot_ac": "A0A3Q1LK42", "gene_name": "FKBP8", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK42" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK42" } ] } ] }, { "uniprot_ac": "A0A3Q1LSB7", "gene_name": "LOC786614", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB7" } ] } ] }, { "uniprot_ac": "A0A3Q1M4A4", "gene_name": "LOC112445968", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1M4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4A4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1M4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4A4" } ] } ] }, { "uniprot_ac": "A0AAA9RV00", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] } ] }, { "uniprot_ac": "A0AAA9TG77", "gene_name": "FKBP15", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9TG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG77" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9TG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG77" } ] } ] }, { "uniprot_ac": "A0AAA9U018", "gene_name": "AIP", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9U018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U018" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9U018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U018" } ] } ] }, { "uniprot_ac": "A0AAF6YJC8", "gene_name": "FKBP6", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAF6YJC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJC8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAF6YJC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJC8" } ] } ] }, { "uniprot_ac": "A0AAF6YJR2", "gene_name": "FKBP3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAF6YJR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJR2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAF6YJR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJR2" } ] } ] }, { "uniprot_ac": "A0ABI0NKM5", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0ABI0NKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0ABI0NKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM5" } ] } ] }, { "uniprot_ac": "A0ABI0NMT7", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0ABI0NMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0ABI0NMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT7" } ] } ] }, { "uniprot_ac": "A4FV72", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A4FV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV72" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A4FV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV72" } ] } ] }, { "uniprot_ac": "A6QPY8", "gene_name": "PIN4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A6QPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPY8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A6QPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPY8" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B9G4", "gene_name": "PPIL3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "E1B9G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "E1B9G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G4" } ] } ] }, { "uniprot_ac": "F1MNW5", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1MNW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1MNW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW5" } ] } ] }, { "uniprot_ac": "F1MU79", "gene_name": "FKBP4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1MU79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU79" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1MU79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU79" } ] } ] }, { "uniprot_ac": "F1N4S5", "gene_name": "FKBP14", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1N4S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4S5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1N4S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4S5" } ] } ] }, { "uniprot_ac": "F1N6W2", "gene_name": "PPIL4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1N6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1N6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F6RD06", "gene_name": "FKBP7", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F6RD06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD06" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F6RD06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD06" } ] } ] }, { "uniprot_ac": "G3MXV0", "gene_name": "FKBP5", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "G3MXV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "G3MXV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ] } ] }, { "uniprot_ac": "G3X8B1", "gene_name": "LOC613401", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "G3X8B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "G3X8B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ] } ] }, { "uniprot_ac": "P18203", "gene_name": "FKBP1A", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P18203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18203" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P18203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18203" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P26882", "gene_name": "PPID", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P26882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26882" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P26882", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26882" } ] } ] }, { "uniprot_ac": "P26884", "gene_name": "FKBP3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P26884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26884" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P26884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26884" } ] } ] }, { "uniprot_ac": "P30404", "gene_name": "PPIF", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P30404", "database": 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"A0AAA9SMM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YYP8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YYP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YYP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YYP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZU1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVALPGQMPRRWLHSAIPLAVFALLLVYLWARNLRCGSGTQSCIAEGPPPFQVQQQSGPVEGAEWEEPQCLGPQGMLGRIMRQFRASLKPEGDVELSQYLAGWRDLVRFVTPLGSIFAFATSEASAKVTALEALVHGPQAAHYTSLGTMVAWERPEIASSPSRASGSVSMLLLHRALRWSQLCLHRVATGMLGGPDAGVQCSDAYGTALAPHHSWLVRQAAHLAFLAFPGRGRLLKLMCPGARETEARAAVARAAGTLEDVYNRTQGLLAERGLLELA", "length": 279, "header": "tr|G3MZU1-1|G3MZU1_BOVIN Isoform 1 of Glycolipid transfer protein domain containing 2 OS=Bos taurus OX=9913 GN=GLTPD2 PE=3 SV=2 CANONICAL=G3MZU1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SMM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMM1/entry", "sequence": { "sequence": "MGVALPGQMPRRWLHSAIPLAVFALLLVYLWARNLRCGSGTQSCIAEGPPPFQVQQQSGPVEGAEWEEPQCLGPQGMLGRIMRQFRASLKPEGDVELSQYLAGWRDLVRSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQPFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAEPGVERQVLLGDQIPKFTIATLPPL", "length": 291, "header": "tr|A0AAA9SMM1-1|G3MZU1_BOVIN Computationally mapped isoform of Glycolipid transfer protein domain containing 2 OS=Bos taurus OX=9913 GN=GLTPD2 PE=3 SV=1 CANONICAL=G3MZU1-1" }, "locus": { "chromosome": "19", "start_pos": 26572537, "end_pos": 26564929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127915.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127915.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085115.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085115.1" } ] } }, { "isoform_ac": "A0AAF6YYP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YYP8/entry", "sequence": { "sequence": "MGVALPGQMPRRWLHSAIPLAVFALLLVYLWARNLRCGSGTQSCIAEGPPPFQVQQQSGPVEGAEWEEPQCLGPQGMLGRIMRQFRASLKPEGDVELSQYLAGWRDLVSHAAIKRSLSQKNFPYAFLFPSAVNQKSSEHDLKRVTEHFTTVALRQYRKRKMAATLVAARGTRPAPAWGPEAIAPDWENREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQPFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAEPGVERQVLLGDQIPKFTIATLPPL", "length": 399, "header": "tr|A0AAF6YYP8-1|G3MZU1_BOVIN Computationally mapped isoform of Glycolipid transfer protein domain containing 2 OS=Bos taurus OX=9913 GN=GLTPD2 PE=3 SV=1 CANONICAL=G3MZU1-1" }, "locus": { "chromosome": "19", "start_pos": 26572537, "end_pos": 26564929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017816.4", "url": "https://www.ensembl.org/id/ENSBTAT00000017816.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017816.3", "url": "https://www.ensembl.org/id/ENSBTAP00000017816.3" } ] } }, { "isoform_ac": "G3MZU1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1/entry", "sequence": { "sequence": "MGVALPGQMPRRWLHSAIPLAVFALLLVYLWARNLRCGSGTQSCIAEGPPPFQVQQQSGPVEGAEWEEPQCLGPQGMLGRIMRQFRASLKPEGDVELSQYLAGWRDLVRFVTPLGSIFAFATSEASAKVTALEALVHGPQAAHYTSLGTMVAWERPEIASSPSRASGSVSMLLLHRALRWSQLCLHRVATGMLGGPDAGVQCSDAYGTALAPHHSWLVRQAAHLAFLAFPGRGRLLKLMCPGARETEARAAVARAAGTLEDVYNRTQGLLAERGLLELA", "length": 279, "header": "tr|G3MZU1-1|G3MZU1_BOVIN Isoform 1 of Glycolipid transfer protein domain containing 2 OS=Bos taurus OX=9913 GN=GLTPD2 PE=3 SV=2 CANONICAL=G3MZU1-1" }, "locus": { "chromosome": "19", "start_pos": 26572537, "end_pos": 26571236, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063979.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063979.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055094.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055094.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100300004", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300004", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y8A9-1", "protein_name": "Glycolipid transfer protein domain containing 2", "gene_name": "Gltpd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLGVSLSPALGRWFRHAIPFAIFTLLLLYISVWLFHEWPFELPAQRTQQSGLWELKLSSPSPALTSLLPVTSGVLPGCRPGVQSCNPERALPSQIGPALRPLVVPEKEEPPCLRPHGLLGRMVSPFLACMSPEGDVELSQYLAGWRELLRLLTPLGSVFAFATSEASNKVTALEAHVHGPDASHYTSLVTMATWERRAVLLERPGTTPRHLARPSGSQTLLLLHRALRWSQLCLHRVATGKLGGPEAGAQCRDAYSTALAPYHPWLIRQAARLAILTLPSRSRLLQLACPGTGEADARVALARAARVLEDVYNRTQGLLASHGLLQLA", "length": 329 }, "evidence": [ { "id": "G3MZU1", "url": "https://omabrowser.org/oma/group/G3MZU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2CF29-1", "protein_name": "Glycolipid transfer protein domain-containing protein 2 precursor", "gene_name": "gltpd2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVRCRACVVVIFILLLLGSLCLHRILEHHSEVYSVKIKVVSLVTDNTSDAPLSVCPDQSFQIAYLLAHLQAAPLAANDVLLKPYLASWDELIKFLEALGPIVGIISQEIESKTTIIRDLAQKAEEEEKKMIERKETTKQLAQSKSSNYSKMDQTLSSGYTSVRSMIKMELENGLVDFQTQTNSGCRTLLRLHRALLWLQNFLHELGKDVAKGERLRRPSDLCKETYQRTLARHHSWWARKAAELAFLAMPERSYFYKLVCVKTQAEASVVLNRVVKAIEKVYKRNEVALQEHDMLDLP", "length": 299 }, "evidence": [ { "id": "G3MZU1", "url": "https://omabrowser.org/oma/group/G3MZU1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NH11-1", "protein_name": "Glycolipid transfer protein domain-containing protein 2", "gene_name": "GLTPD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVAARPPALRHWFSHSIPLAIFALLLLYLSVRSLGARSGCGPRAQPCVPGETAPFQVRQESGTLEAPERKQPPCLGPRGMLGRMMRRFHASLKPEGDVGLSPYLAGWRALVEFLTPLGSVFAFATREAFTKVTDLEARVHGPDAEHYWSLVAMAAWERRAGLLEQPGAAPRDPTRSSGSRTLLLLHRALRWSQLCLHRVATGALGGPDAGVQCSDAYRAALGPHHPWLVRQTARLAFLAFPGRRRLLELACPGATEAEARAALVRAAGTLEDVYNRTQSLLAERGLLQLA", "length": 291 }, "evidence": [ { "id": "G3MZU1", "url": "https://omabrowser.org/oma/group/G3MZU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1RFV4-1", "protein_name": "Glycolipid transfer protein domain containing 2", "gene_name": "GLTPD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGVTSLSRRVPRCWRRSAIPLIIFTLLLLYLWAQSLRALSGCRSGTQSCIAKGLPPFQAQQQSGSLEGLEREEPQCLSPHGMLGRIMRPFRASLNPKGDVELSQYLAGWRELVRFLTPLGSIFSFATSEAFAKVTVLEALVHGPEAAHYTSLATMVAWERPGVAPRHSTRNPGSLTMLLLHRALRWSQLCLHRVATGPPGGPDAGAQCSDAYSTALAPHHPWLVRQAAHLAFLAFPGRGRLLELACPGVKEAEARAALAQAAGTLEDVYNRTQGLLAERRLLQLA", "length": 285 }, "evidence": [ { "id": "G3MZU1", "url": "https://omabrowser.org/oma/group/G3MZU1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8K0R6-1", "protein_name": "Glycolipid transfer protein domain-containing protein 2", "gene_name": "Gltpd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVMGVSLSPALGRWFRHAIPFAILTLLLLYISIWFFYEWPFPLPAQRTQQSGLRGLKLPSPSPVLGSLLSFPAGVQSCNPERPLPSQTGPAARPLVVPEKEELPCLGPHGALGRMVSPFLACMSPEGDVALSQYLAGWRELLRFLTPLGTVFAFATSEAFNKVTDLEARVHGPNASHYTSLMTMITWERGAGLLQRPGTEPGHSAGSSGSRTLLLLHRALRWSQLCLHRVATGTLGGPDAGTQCGEAYSTALAPHHPWLIRQAARLAILALPSRGRLLQLACPGTGEADARVALARAAGVLEDVYNRTQGLLAGHGLLQLA", "length": 321 }, "evidence": [ { "id": "G3MZU1", "url": "https://omabrowser.org/oma/group/G3MZU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" }, { "name": "proteasome core complex", "id": "GO:0005839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005839", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" }, { "name": "ceramide transport", "id": "GO:0035627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035627", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" }, { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "threonine-type endopeptidase activity", "id": "GO:0004298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004298", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" }, { "name": "ceramide 1-phosphate binding", "id": "GO:1902387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902387", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" }, { "name": "ceramide 1-phosphate transfer activity", "id": "GO:1902388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902388", "evidence": [ { "database": "UniProtKB", "id": "G3MZU1", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZU1" }, { "id": "PF08718", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08718" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycolipid transfer protein", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 240, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.25.1", "ec_name": "Cleavage of peptide bonds with very broad specificity.", "evidence": [ { "id": "3.4.25.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.25.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7B4-1", "uniprot_ac": "G3X7B4", "uniprot_id": "G3X7B4_BOVIN", "mass": { "chemical_mass": 190906.0, "monoisotopic_mass": 190906.0 }, "refseq": { "ac": "XP_059742295", "name": "SH3 and multiple ankyrin repeat domains protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742295" }, "gene_names": [ { "name": "SHANK3", "type": "recommended", "evidence": [ { "id": "G3X7B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7B4" } ] }, { "name": "SHANK3", "type": "synonym", "evidence": [ { "id": "XP_059742295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742295" } ] } ], "protein_names": [ { "name": "SH3 and multiple ankyrin repeat domains protein 3", "type": "recommended", "evidence": [ { "id": "G3X7B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7B4/entry#names_and_taxonomy" } ] }, { "name": "Proline-rich synapse-associated protein 2", "type": "synonym", "evidence": [ { "id": "G3X7B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7B4/entry#names_and_taxonomy" } ] }, { "name": "SH3 and multiple ankyrin repeat domains protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059742295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742295" } ] } ], "function": [ { "annotation": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.", "evidence": [ { "database": "UniProtKB", "id": "G3X7P4", "url": "https://www.uniprot.org/uniprotkb/G3X7P4#function" }, { "database": "UniProtKB", "id": "ARBA00025297", "url": "https://www.uniprot.org/uniprotkb/ARBA00025297#function" }, { "database": "UniProtKB", "id": "G3X7B4", "url": "https://www.uniprot.org/uniprotkb/G3X7B4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7B4", "url": "https://www.uniprot.org/uniprotkb/G3X7B4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SHANK3", "url": "https://www.uniprot.org/uniprotkb/G3X7B4", "locus": { "chromosome": "5", "start_pos": 120008278, "end_pos": 119958967, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030180", "url": "https://www.ensembl.org/id/ENSBTAG00000030180" } ] } } ], "crossref": [ { "id": "ENSBTAG00000030180", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030180", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06746", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06746", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512428", "url": "https://www.ncbi.nlm.nih.gov/gene/512428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512428", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQR1", "url": "https://www.orthodb.org/?gene=A0A3Q1LQR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X7B4", "url": "https://www.orthodb.org/?gene=G3X7B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X7P4", "url": "https://www.orthodb.org/?gene=G3X7P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24135", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24135", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24135:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24135:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8853659", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8853659", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059742295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742295", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7B4", "url": "https://www.uniprot.org/uniprotkb/G3X7B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7B4-1", "url": "https://www.uniprot.org/uniprotkb/G3X7B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7P4", "url": "https://www.uniprot.org/uniprotkb/G3X7P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7P4-1", "url": "https://www.uniprot.org/uniprotkb/G3X7P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLSRAAAAAAAAAPAEPSEPLSPAPAPAPAPPGPLPRSAADGAPVGGRGGPGRGEEPRGAQLPAASGPGPGAGMDGPGASAVIVRVGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQEYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMEYVQLHSTEKVARLLDKGLDPNFHDPDSGECPLSLAAQLDDATDLLKVLKNGGAHLDFRTRDGLTAVHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEVHQACRFGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSALASPRPLQRSASDINLKGEVQPAASPGPSLRSLPHQLLLQRLQEEKDRDRDGDQQNDSGPATGRGSQSKISPSGPGGPGGPGPAPGPGPAPPAPPAPPPRGPKRKLYSAVPGRKFIAVKAHSPQGEGEIPLHRGEAVKVLSIGEGGFWEGTVKGRTGWFPADCVEEVQMRQYDARHETREDRTKRLFRHYTVGSYDSLSAHSDYVIDDKVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTRKPEEDGARRRAPPPPKRAPSTTLTLRSKSMTAELEELEKLDEILAAAAEPALRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGPEKLPGSLRKGIPRTKSVGEDEKLASLLEGRFPRSTSMQDSVREGRGIPPPPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRAYDTVRSSFKPGLEARLGAGAPGLYDSGAALGPLPYPERQKRARSMIILQDSAPEAADASRPPPAATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVVGSFAREPSPTHRGPRPSGLDYGPGDGPGLAFGGPAPSKDRRLEERRRSTVFLSVGAIEGASPSADMPSLQPSRSIDERLLGPGATITGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDTDRPGPLFVDVQARDSERGPLASPAFSPRSPAWVPVPARREPEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGHEPSGLGAEEQRPGTPELAPAPTQSAVVAEPLPSPRAQPPGSAPTDPGPGQGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLATPLPGPGPSPTTVPGPASGKPSSEPPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAATAGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVITELSSRLQQLNKDTRSLGEEPAGGLGGLLDPAKKSPIAAARLFSSLGELSTISAQQRSPGGPGGGASYPVRPGGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPAPGPGPGAPSPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELGVTRVGHRMNIERALRQLDGS", "length": 1800, "header": "tr|G3X7B4-1|G3X7B4_BOVIN Isoform 1 of SH3 and multiple ankyrin repeat domains protein 3 OS=Bos taurus OX=9913 GN=SHANK3 PE=4 SV=3 CANONICAL=G3X7B4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQR1/entry", "sequence": { "sequence": "MAQKLGNPGEGSLAQFRQGQRKGGGPAAGGKLLGQQQHKVTKHPRARCRLSIWHTGLCVKPVDEGHRAENRPQAGQRPTQTHLVWPALPLALQLQCAPSHCTGPLPPSLLPGCLASGSPPGCPLWFCPARPLRAGANSLSHCSLLPICMWLLCLAARWSRAPAVLFSSLGELSTISAQQRSPGGPGGGASYPVRPGGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPAPGPGPGAPSPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELGVTRVGHRMNIERALRQLDGS", "length": 361, "header": "tr|A0A3Q1LQR1-1|G3X7B4_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains protein 3 OS=Bos taurus OX=9913 GN=SHANK3 PE=4 SV=2 CANONICAL=G3X7B4-1" }, "locus": { "chromosome": "5", "start_pos": 120006340, "end_pos": 120004256, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076026.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076026.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059437.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059437.2" } ] } }, { "isoform_ac": "G3X7B4-1", "url": "https://www.uniprot.org/uniprotkb/G3X7B4/entry", "sequence": { "sequence": "MQLSRAAAAAAAAAPAEPSEPLSPAPAPAPAPPGPLPRSAADGAPVGGRGGPGRGEEPRGAQLPAASGPGPGAGMDGPGASAVIVRVGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQEYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMEYVQLHSTEKVARLLDKGLDPNFHDPDSGECPLSLAAQLDDATDLLKVLKNGGAHLDFRTRDGLTAVHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEVHQACRFGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSALASPRPLQRSASDINLKGEVQPAASPGPSLRSLPHQLLLQRLQEEKDRDRDGDQQNDSGPATGRGSQSKISPSGPGGPGGPGPAPGPGPAPPAPPAPPPRGPKRKLYSAVPGRKFIAVKAHSPQGEGEIPLHRGEAVKVLSIGEGGFWEGTVKGRTGWFPADCVEEVQMRQYDARHETREDRTKRLFRHYTVGSYDSLSAHSDYVIDDKVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTRKPEEDGARRRAPPPPKRAPSTTLTLRSKSMTAELEELEKLDEILAAAAEPALRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGPEKLPGSLRKGIPRTKSVGEDEKLASLLEGRFPRSTSMQDSVREGRGIPPPPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRAYDTVRSSFKPGLEARLGAGAPGLYDSGAALGPLPYPERQKRARSMIILQDSAPEAADASRPPPAATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVVGSFAREPSPTHRGPRPSGLDYGPGDGPGLAFGGPAPSKDRRLEERRRSTVFLSVGAIEGASPSADMPSLQPSRSIDERLLGPGATITGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDTDRPGPLFVDVQARDSERGPLASPAFSPRSPAWVPVPARREPEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGHEPSGLGAEEQRPGTPELAPAPTQSAVVAEPLPSPRAQPPGSAPTDPGPGQGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLATPLPGPGPSPTTVPGPASGKPSSEPPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAATAGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVITELSSRLQQLNKDTRSLGEEPAGGLGGLLDPAKKSPIAAARLFSSLGELSTISAQQRSPGGPGGGASYPVRPGGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPAPGPGPGAPSPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELGVTRVGHRMNIERALRQLDGS", "length": 1800, "header": "tr|G3X7B4-1|G3X7B4_BOVIN Isoform 1 of SH3 and multiple ankyrin repeat domains protein 3 OS=Bos taurus OX=9913 GN=SHANK3 PE=4 SV=3 CANONICAL=G3X7B4-1" }, "locus": { "chromosome": "5", "start_pos": 120006340, "end_pos": 119959166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023459.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023459.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023459.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023459.7" } ] } }, { "isoform_ac": "G3X7P4-1", "url": "https://www.uniprot.org/uniprotkb/G3X7P4/entry", "sequence": { "sequence": "MQLSRAAAAAAAAAPAEPSEPLSPAPAPAPAPPGPLPRSAADGAPVGGRGGPGRGEEPRGAQLPAASGPGPGAGMDGPGASAVIVRVGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQEYPPNLDTPLPYLESRWVPFSALSLPEQFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMEYVQLHSTEKVARLLDKGLDPNFHDPDSGECPLSLAAQLDDATDLLKVLKNGGAHLDFRTRDGLTAVHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEVHQACRFGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSALASPRPLQRSASDINLKGEVQPAASPGPSLRSLPHQLLLQRLQEEKDRDRDGDQQNDSGPATGRGSQSKISPSGPGGPGGPGPAPGPGPAPPAPPAPPPRGPKRKLYSAVPGRKFIAVKAHSPQGEGEIPLHRGEAVKVLSIGEGGFWEGTVKGRTGWFPADCVEEVQMRQYDARHETREDRTKRLFRHYTVGSYDSLSAHSDYVIDDKVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTRKPEEDGARRRAPPPPKRAPSTTLTLRSKSMTAELEELASIRRRKGEKLDEILAAAAEPALRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGPEKLPGSLRKGIPRTKSVGEDEKLASLLEGRFPRSTSMQDSVREGRGIPPPPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRAYDTVRSSFKPGLEARLGAGAPGLYDSGAALGPLPYPERQKRARSMIILQDSAPEAADASRPPPAATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVVGSFAREPSPTHRGPRPSGLDYGPGDGPGLAFGGPAPSKDRRLEERRRSTVFLSVGAIEGASPSADMPSLQPSRSIDERLLGPGATITGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDTDRPGPLFVDVQARDSERGPLASPAFSPRSPAWVPVPARREPEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGHEPSGLGAEEQRPGTPELAPAPTQSAVVAEPLPSPRAQPPGSAPTDPGPGQGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLATPLPGPGPSPTTVPGPASGKPSSEPPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAATAGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVITELSSRLQQLNKDTRSLGEEPAGGLGGLLDPAKKSPIAAARLFSSLGELSTISAQQRSPGGPGGGASYPVRPGGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPAPGPGPGAPSPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELGVTRVGHRMNIERALRQLDGS", "length": 1822, "header": "tr|G3X7P4-1|G3X7B4_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains protein 3 OS=Bos taurus OX=9913 GN=SHANK3 PE=4 SV=3 CANONICAL=G3X7B4-1" }, "locus": { "chromosome": "5", "start_pos": 120006340, "end_pos": 119959166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042578.5", "url": "https://www.ensembl.org/id/ENSBTAT00000042578.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040212.5", "url": "https://www.ensembl.org/id/ENSBTAP00000040212.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1310, "start_aa": "Thr", "end_pos": 1310, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1310", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 677, "start_aa": "Thr", "end_pos": 677, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr677", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": 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"length": 1476, "header": "tr|F1MB21-1|G3MZA1_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 40 OS=Bos taurus OX=9913 GN=ARHGEF40 PE=3 SV=4 CANONICAL=G3MZA1-1" }, "locus": { "chromosome": "10", "start_pos": 26023736, "end_pos": 26002474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017829.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017829.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017829.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017829.6" } ] } }, { "isoform_ac": "G3MXG4-1", "url": "https://www.uniprot.org/uniprotkb/G3MXG4/entry", "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFKATAPTLLGQVFQVVERTYREDALRYTLDFLVPAKHLLAKIQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPNEACAYLFTPEWLQGINKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKGGLMVGHRPSTLPPELPSGPPGLPSPPLPEEALGTRSPGDGHNAPAEGPEGEYVELLEVTLPVRGSPMDAEGSSGLSRTRTVPTRKGAGGKGRHRRHRAWMHQKGLGPRDQDGARPPGEGSSTGASPGSPPGAEVEAFPEAAALEVSEPLAEALGEASESCPLRPGEVGAGPGQGAEGLPGTPRRTGKGNRRKKRAAGRGALNRGGDSAPLSPGDKEETSHQEALVSLPPPNEHELPGCSPVKEEHEGSGKPEPEPREELKPPDEKEPRSQEVCGPVEERAREREQEGLSLVCMAAPNDPEGLLSDPLKPPPETVQEVKGESIPEEGPPVSISDDPGVAWDLLASGFLILTGGVDQSGRALLTITPPCPPEEPPPSQDVLSTALHYLHSLLRPDLQILGLSVLLDLRKAPPLPPALIPVLSQLQDSGDPPLIQRLLLLTLDEPPAELHGLQGAELLSEGDLKRVAKPEELQWDLGGHREPSPSHWVETHQQVARLCHLCRGVLGSIRQAIEELERAAEPEGEEVVGMPEPLQKVLADPRLTELQRDGGAILMKLRSTHSSKLEGPGPAALYQEVDEAIHQLVRLSNLHVQQQEQRQRLHRLQQALQWLSGPGEEQLASFAVPGDSLPALQETELRFRAFSAEVQERLAQARETLALEEDAASQKLLDVFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGSARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCRARCQELERRIQQQLGEEASPRGHRRRRADSASSGGAPRGPHSPSPSLSSLLLPSSPGPRAAPSHCSLAPCGEDYEEEGAELGPEAEGRPPRTVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPEGPWGVGTPRMERKRSISAQQRLVSELITCEQEYVAALSEPVPPPGPELTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQFSLYAQYVKHRHKLETGLTALSPPTKGTLEGGPHLPRALQQPLEQLARYGRLLEELLREAGPEPSSERQALGAAVQLLREQEIRGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCFRHVFLFEHLLLFSKLKGPEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQAASPEIKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQIALAPETLDSSGDVSPGPRNSPNLQAPHPGSSTPILSSGGILGLSRQSHTRALSDPTTPL", "length": 1520, "header": "tr|G3MXG4-1|G3MZA1_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 40 OS=Bos taurus OX=9913 GN=ARHGEF40 PE=3 SV=3 CANONICAL=G3MZA1-1" }, "locus": { "chromosome": "10", "start_pos": 26023736, "end_pos": 26002474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063701.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063701.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054231.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054231.3" } ] } }, { "isoform_ac": "G3MZA1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1/entry", "sequence": { "sequence": "MAPARAGFCPLLLLLLLGLWVAEDAVSARPGNMTPAQWFETQHVQPSPQGCNAAMRKINKFSKHCKDLNTFLHESFSSVATTCQTPNITCKNHENNCHQSQKPVSLTECKLTSRRYPDCKYKEKKQITSYIVAYPAERRKGRRLAFRGGA", "length": 150, "header": "tr|G3MZA1-1|G3MZA1_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 40 OS=Bos taurus OX=9913 GN=ARHGEF40 PE=3 SV=2 CANONICAL=G3MZA1-1" }, "locus": { "chromosome": "10", "start_pos": 26058811, "end_pos": 26020990, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065979.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065979.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054897.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054897.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:527362", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527362", "resource": "KEGG Pathway" }, { "id": "R-BTA-6803157", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6803157", "resource": "Reactome", "description": "Antimicrobial peptides" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZUE2-1", "protein_name": "Rho guanine nucleotide exchange factor 40", "gene_name": "Arhgef40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPNEACAYLFTPEWLQGINKDRPTGRLSTCLLSAPSGIQRLPWAELVCPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPVRGSPIDAEASGLSRTRTVPARKTTGGKGRHRRHRAWMNQKGPGSRDQDGTRPPGEGSSTGASSDSPSGAEADPDAAVLEAPEPPAEASGEASESCLLSGEAVGGVGQGTEGPPDTPRRTGKGNRRKKRAAGRGAVSRGGESTPLSPRDKEETRQPEVLSLPSPSEQEPVECSLVKEKEDSGKPESESKEELKPADEKEPAPPEDYEPPEEGNRESEKEELPPECTAGSTGPEWFPSEPPTQPLETVQDVKEDSIPEETPPVSASDDPLIVWDLMSSGFFILTGGVDQTGRALLRITPPPPCLPEEPSPSQETLSTALRYLHSLLRPDLQLLGLTILLDLRKVPPLPPALLPALSQLQDSGDPPFIQRLLILTHEDPPEELCGFQGAELLSEKDLKRVAKPEELQWDLGGHRDLSPNHWAEIHQEVARLCTLCQGVLTSVRQAIEELEGAAESKEEESVGMPEPLQKVLADPRLTALQRNGGAILMRLRSTHSSKLEGPGPAVLYQEVDEAIHQLVRLSNLRVQQQEQRQRLRQVQEVLQWLSGPGEEQLASFTIPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDITSQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGCARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCRARCQELERRIQQQLGEEASPRSHRRRRADSASSAGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPEADGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVSELIDCEQEYITTLNEPVPPPGPELTPGLRCTWAAALSVRERLRSFHGTHFLQELQGCTAHPLRIGACFLRHGDQFNLYAQFVKHRHKLESGLTALTPSVKGSMEGSPCLPRALQQPLEQLARYAQLLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLREQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKSKGSEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQSPNPGSSTPALSSGGILGLSRQSHSRALSDPTTPL", "length": 1515 }, "evidence": [ { "id": "G3MZA1", "url": "https://omabrowser.org/oma/group/G3MZA1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UPH7-1", "protein_name": "Rho guanine nucleotide exchange factor 40", "gene_name": "Arhgef40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGINKDRPTGRLSTCLLSAPSGIQRLPWAELVCPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPVRGSPVDAEASGLSRTRTVPARKSTGGKGRHRRHRAWMNQKGLGSRDQDGTRPPGEGSSTGASSDSPSGAEADPDATALQASEPPAEALGEAPESCLLSGEAVGGVGQGAEGPPGTPRRTGKGNRRKKRAAGRGAGSRGGEGTSLSPRDKEETRQQEVLVSLPSPSEQEPAECSLVKEKEDSGKQESESKEELKPADEKEPARPEDYEPPEEEIRESEKEELTPQCTAGSTGPEWFPSEPSTQPLETVQNVKGDSLPEETPPVSVLDDPVVAWDLMASGFFVLTGGVDQTGRALLTITPPPPCLPEESSPSQETLSTALRYLHSLLRPDLQLLGLTILLDLRKAPPLPPALLPALSQLQDSGEPPLIQRLVILIHEDPPAELCGFQGAELLSEKDLKRVAKPEELQWDLGGHRDLSPNHWAEIHQEVARLCTLCQGVLTSVRQAIEELEGTAEPKEEEAVGMPEPLQKVLADPRLTALQRNGGAILMRLRSAHSSKLEGPGPAELYQEVDEAIHQLVRLSNLRVQQQEERQRLRQVQQVLQWLSGPGEEQLASFSMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDLTSQKVLDIFEQRLEQAESGLHRALRLQRFFQQAHEWVDEGSARLAGAGSGREALLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCRARCQELERRIQQQLGEEASPRSHRRRRADSASSAGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPETDGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVSELIACEQEYVTTLNEPVPLPGPELTPELRCTWAAALSVRERLRSFHGTHFLQELQGCAAHPLRIGACFLRHGDQFNLYAQFVKHRHKLESGLAALTPSVKGSMESSPCLPRALQQPLEQLARYGQLLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKLKGSEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQPPSPGSSTPALTSGGILGLSRQSHSRALSDPTTPL", "length": 1517 }, "evidence": [ { "id": "G3MZA1", "url": "https://omabrowser.org/oma/group/G3MZA1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TER5-1", "protein_name": "Rho guanine nucleotide exchange factor 40", "gene_name": "ARHGEF40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYREDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQEVPVPNEACAYLFTPEWLQGINKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSPPLPEEALGTRSPGDGHNAPVEGPEGEYVELLEVTLPVRGSPTDAEGSPGLSRVRTVPTRKGAGGKGRHRRHRAWMHQKGLGPRGQDGARPPGEGSSTGASPESPPGAEAVPEAAVLEVSEPPAEAVGEASGSCPLRPGELRGGGGGGQGAEGPPGTPRRTGKGNRRKKRAAGRGALSRGGDSAPLSPGDKEDASHQEALGNLPSPSEHKLPECHLVKEEYEGSGKPESEPKELKTAGEKEPQLSEACGPTEEGAGERELEGPGLLCMAGHTGPEGPLSDTPTPPLETVQEGKGDNIPEEALAVSVSDHPDVAWDLMASGFLILTGGVDQSGRALLTITPPCPPEEPPPSRDTLNTTLHYLHSLLRPDLQTLGLSVLLDLRQAPPLPPALIPALSQLQDSGDPPLVQRLLILIHDDLPTELCGFQGAEVLSENDLKRVAKPEELQWELGGHRDPSPSHWVEIHQEVVRLCRLCQGVLGSVRQAIEELEGAAEPEEEEAVGMPKPLQKVLADPRLTALQRDGGAILMRLRSTPSSKLEGQGPATLYQEVDEAIHQLVRLSNLHVQQQEQRQCLRRLQQVLQWLSGPGEEQLASFAMPGDTLSALQETELRFRAFSAEVQERLAQAREALALEENATSQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGFARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCQARCQELERRIQQHVGEEASPRGYRRRRADGASSGGAQWGPRSPSPSLSSLLLPSSPGPRPAPSHCSLAPCGEDYEEEGPELAPEAEGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRARGPDGPWGVGTPRMERKRSISAQQRLVSELIACEQDYVATLSEPVPPPGPELTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQFSLYAQYVKHRHKLENGLAALSPLSKGSMEAGPYLPRALQQPLEQLTRYGRLLEELLREAGPELSSECRALGAAVQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEHLLLFSKLKGPEGGSEMFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPEIKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLAPETLDSSGDVSPGPRNSPSLQPPHPGSSTPTLASRGILGLSRQSHARALSDPTTPL", "length": 1519 }, "evidence": [ { "id": "G3MZA1", "url": "https://omabrowser.org/oma/group/G3MZA1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" }, { "name": "RNA nuclease activity", "id": "GO:0004540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004540", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "G3MZA1", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZA1" }, { "id": "SM00092", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribonuclease A-domain", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 137, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0R5-1", "uniprot_ac": "G3N0R5", "uniprot_id": "G3N0R5_BOVIN", "mass": { "chemical_mass": 75031.0, "monoisotopic_mass": 75031.0 }, "refseq": {}, "gene_names": [ { "name": "HSPD1", "type": "recommended", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ] } ], "protein_names": [ { "name": "60 kDa heat shock protein, mitochondrial", "type": "recommended", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5/entry#names_and_taxonomy" } ] }, { "name": "5.6.1.7", "type": "synonym", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5/entry#names_and_taxonomy" } ] }, { "name": "60 kDa chaperonin", "type": "synonym", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5/entry#names_and_taxonomy" } ] }, { "name": "Chaperonin 60", "type": "synonym", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5/entry#names_and_taxonomy" } ] }, { "name": "Heat shock protein 60", "type": "synonym", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial matrix protein P1", "type": "synonym", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SVC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVC5#function" }, { "database": "UniProtKB", "id": "ARBA00037436", "url": "https://www.uniprot.org/uniprotkb/ARBA00037436#function" }, { "database": "UniProtKB", "id": "A0AAA9TBS7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBS7#function" }, { "database": "UniProtKB", "id": "F1MUZ9", "url": "https://www.uniprot.org/uniprotkb/F1MUZ9#function" }, { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HSPD1", "url": "https://www.uniprot.org/uniprotkb/G3N0R5", "locus": { "chromosome": "22", "start_pos": 13635240, "end_pos": 13638437, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047441", "url": "https://www.ensembl.org/id/ENSBTAG00000047441" } ] } } ], "crossref": [ { "id": "G3N0R5", "url": "https://alphafold.ebi.ac.uk/entry/G3N0R5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012586", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012586", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03344", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03344", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MUZ9", "url": "https://www.orthodb.org/?gene=F1MUZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1268020", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1268020", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SVC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVC5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBS7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUZ9", "url": "https://www.uniprot.org/uniprotkb/F1MUZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1MUZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0R5-1", "url": "https://www.uniprot.org/uniprotkb/G3N0R5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRLTLDPHRARLFPERSGTARSPGTSLSEPERAEPAGLARRGYAPAPRRLTRAFRTPEPSFPSPLSRSAGESQSFPRRRRPGPAEPGLVGARGGPSRAAWIARPAGHSREGLPTSVRGVGRLYSHRSSEMLRLPAVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALESITPANEDQKTGIEIIKKTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGGMGGMGGGMGGGMF", "length": 703, "header": "tr|G3N0R5-1|G3N0R5_BOVIN Isoform 1 of 60 kDa heat shock protein, mitochondrial OS=Bos taurus OX=9913 GN=HSPD1 PE=1 SV=1 CANONICAL=G3N0R5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SVC5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVC5/entry", "sequence": { "sequence": "MLRLPAVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALESITPANEDQKTGIEIIKKTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGGMGGMGGGMGGGMF", "length": 482, "header": "tr|A0AAA9SVC5-1|G3N0R5_BOVIN Computationally mapped isoform of 60 kDa heat shock protein, mitochondrial OS=Bos taurus OX=9913 GN=HSPD1 PE=1 SV=1 CANONICAL=G3N0R5-1" }, "locus": { "chromosome": "2", "start_pos": 86044487, "end_pos": 86035953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131992.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131992.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090421.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090421.1" } ] } }, { "isoform_ac": "A0AAA9TBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBS7/entry", "sequence": { "sequence": "MLRLPAVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALESITPANEDQKTGIEIIKKTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGGMF", "length": 562, "header": "tr|A0AAA9TBS7-1|G3N0R5_BOVIN Computationally mapped isoform of 60 kDa heat shock protein, mitochondrial OS=Bos taurus OX=9913 GN=HSPD1 PE=1 SV=1 CANONICAL=G3N0R5-1" }, "locus": { "chromosome": "2", "start_pos": 86044487, "end_pos": 86035953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130344.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130344.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093537.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093537.1" } ] } }, { "isoform_ac": "F1MUZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1MUZ9/entry", "sequence": { "sequence": "MLRLPAVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALESITPANEDQKTGIEIIKKTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGGMGGMGGGMGGGMF", "length": 541, "header": "tr|F1MUZ9-1|G3N0R5_BOVIN Computationally mapped isoform of 60 kDa heat shock protein, mitochondrial OS=Bos taurus OX=9913 GN=HSPD1 PE=1 SV=2 CANONICAL=G3N0R5-1" }, "locus": { "chromosome": "2", "start_pos": 86044487, "end_pos": 86035953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016708.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016708.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016708.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016708.6" } ] } }, { "isoform_ac": "G3N0R5-1", "url": "https://www.uniprot.org/uniprotkb/G3N0R5/entry", "sequence": { "sequence": "MTRLTLDPHRARLFPERSGTARSPGTSLSEPERAEPAGLARRGYAPAPRRLTRAFRTPEPSFPSPLSRSAGESQSFPRRRRPGPAEPGLVGARGGPSRAAWIARPAGHSREGLPTSVRGVGRLYSHRSSEMLRLPAVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALESITPANEDQKTGIEIIKKTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGGMGGMGGGMGGGMF", "length": 703, "header": "tr|G3N0R5-1|G3N0R5_BOVIN Isoform 1 of 60 kDa heat shock protein, mitochondrial OS=Bos taurus OX=9913 GN=HSPD1 PE=1 SV=1 CANONICAL=G3N0R5-1" }, "locus": { "chromosome": "2", "start_pos": 86045756, "end_pos": 86035953, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064253.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064253.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055431.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055431.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 184, "start_aa": "Thr", "end_pos": 184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr184", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1268020", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1268020", "resource": "Reactome", "description": "Mitochondrial protein import" }, { "id": "R-BTA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "ATP-dependent protein folding chaperone", "id": "GO:0140662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140662", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "isomerase activity", "id": "GO:0016853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "chaperonin-containing T-complex", "id": "GO:0005832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005832", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "protein import into mitochondrial intermembrane space", "id": "GO:0045041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045041", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "response to cold", "id": "GO:0009409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009409", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "apoptotic mitochondrial changes", "id": "GO:0008637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008637", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" }, { "name": "mitochondrial unfolded protein response", "id": "GO:0034514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034514", "evidence": [ { "database": "UniProtKB", "id": "G3N0R5", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8986181", "name": "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P00829-1", "G3N0R5-1", "Q05B87-1", "F1N1G6-1", "A0AAA9U0N6-1" ], "evidence": [ { "id": "R-BTA-8986181", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8986181" } ] }, { "id": "R-BTA-9838035", "name": "CLPXP binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "P15690-1", "P20000-1", "Q02337-1", "Q32LG3-1", "P20004-1", "A6QLI6-1", "P00829-1", "A7MB35-1", "F1MTT7-1", "Q148N0-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q04467-1", "Q0NXR6-1", "Q29RZ0-1", "Q3MHX5-1", "F1MXW5-1", "F1N155-1", "F1N338-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "F1N206-1", "Q3ZCH0-1", "Q2KHU4-1" ], "evidence": [ { "id": "R-BTA-9838035", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838035" } ] }, { "id": "R-BTA-9838081", "name": "LONP1 degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "Q2KIE6-1", "P15690-1", "P20000-1", "Q32LG3-1", "P20004-1", "A0AAA9S896-1", "P00829-1", "Q5EAD4-1", "Q2TBR0-1", "F1MTT7-1", "Q148N0-1", "P11181-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q0NXR6-1", "Q29RZ0-1", "F1MXW5-1", "F1N338-1", "G3MWG4-1", "A0A140T871-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "O02691-1", "A0A3Q1LR42-1", "Q3ZCH0-1" ], "evidence": [ { "id": "R-BTA-9838081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838081" } ] }, { "id": "R-BTA-9838093", "name": "LONP1 binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "Q2KIE6-1", "P15690-1", "P20000-1", "Q32LG3-1", "P20004-1", "A0AAA9S896-1", "P00829-1", "Q5EAD4-1", "Q2TBR0-1", "F1MTT7-1", "Q148N0-1", "P11181-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q0NXR6-1", "Q29RZ0-1", "F1MXW5-1", "F1N338-1", "G3MWG4-1", "A0A140T871-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "O02691-1", "A0A3Q1LR42-1", "Q3ZCH0-1" ], "evidence": [ { "id": "R-BTA-9838093", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838093" } ] }, { "id": "R-BTA-9838289", "name": "CLPXP degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "P15690-1", "P20000-1", "Q02337-1", "Q32LG3-1", "P20004-1", "A6QLI6-1", "P00829-1", "A7MB35-1", "F1MTT7-1", "Q148N0-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q04467-1", "Q0NXR6-1", "Q29RZ0-1", "Q3MHX5-1", "F1MXW5-1", "F1N155-1", "F1N338-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "F1N206-1", "Q3ZCH0-1", "Q2KHU4-1" ], "evidence": [ { "id": "R-BTA-9838289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838289" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T871", "gene_name": "GLUD1", "activity": [ { "ec_number": "1.4.1.3", "activity": "L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+).", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] }, { "ec_number": "1.4.1.3", "activity": "", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] } ] }, { "uniprot_ac": "A0A3Q1LR42", "gene_name": "NADK2", "activity": [ { "ec_number": "2.7.1.23", "activity": "NAD(+) + ATP = ADP + NADP(+) + H(+).", "evidence": [ { "id": "A0A3Q1LR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR42" } ] }, { "ec_number": "2.7.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1LR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR42" } ] } ] }, { "uniprot_ac": "A0A3Q1LS03", "gene_name": "", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A3Q1LS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS03" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A3Q1LS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS03" } ] } ] }, { "uniprot_ac": "A0A3Q1LS67", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] } ] }, { "uniprot_ac": "A0A3Q1LYU1", "gene_name": "PDK1", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3Q1LYU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYU1" } ] } ] }, { "uniprot_ac": "A0AAA9S896", "gene_name": "LONP1", "activity": [ { "ec_number": "3.4.21.53", "activity": "Hydrolysis of proteins in presence of ATP.", "evidence": [ { "id": "A0AAA9S896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S896" } ] }, { "ec_number": "3.4.21.53", "activity": "", "evidence": [ { "id": "A0AAA9S896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S896" } ] } ] }, { "uniprot_ac": "A0AAA9U0N6", "gene_name": "OTC", "activity": [ { "ec_number": "2.1.3.3", "activity": "carbamoyl phosphate + L-ornithine = L-citrulline + phosphate + H(+).", "evidence": [ { "id": "A0AAA9U0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0N6" } ] }, { "ec_number": "2.1.3.3", "activity": "", "evidence": [ { "id": "A0AAA9U0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0N6" } ] } ] }, { "uniprot_ac": "A6QLI6", "gene_name": "ALAS1", "activity": [ { "ec_number": "2.3.1.37", "activity": "succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA.", "evidence": [ { "id": "A6QLI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLI6" } ] }, { "ec_number": "2.3.1.37", "activity": "", "evidence": [ { "id": "A6QLI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLI6" } ] } ] }, { "uniprot_ac": "A7MB35", "gene_name": "PDHA1", "activity": [ { "ec_number": "1.2.4.1", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "A7MB35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB35" } ] }, { "ec_number": "1.2.4.1", "activity": "", "evidence": [ { "id": "A7MB35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB35" } ] } ] }, { "uniprot_ac": "F1MTT7", "gene_name": "ECI1", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "F1MTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTT7" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "F1MTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTT7" } ] } ] }, { "uniprot_ac": "F1MXW5", "gene_name": "OXSM", "activity": [ { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "F1MXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXW5" } ] }, { "ec_number": "2.3.1.41", "activity": "", "evidence": [ { "id": "F1MXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXW5" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1G6", "gene_name": "COQ2", "activity": [ { "ec_number": "2.5.1.39", "activity": "all-trans-nonaprenyl diphosphate + 4-hydroxybenzoate = 4-hydroxy-3-(all-trans-nonaprenyl)benzoate + diphosphate.", "evidence": [ { "id": "F1N1G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1G6" } ] }, { "ec_number": "2.5.1.39", "activity": "", "evidence": [ { "id": "F1N1G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1G6" } ] } ] }, { "uniprot_ac": "F1N206", "gene_name": "DLD", "activity": [ { "ec_number": "1.8.1.4", "activity": "N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+).", "evidence": [ { "id": "F1N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N206" } ] }, { "ec_number": "1.8.1.4", "activity": "", "evidence": [ { "id": "F1N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N206" } ] } ] }, { "uniprot_ac": "F1N338", "gene_name": "HADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "F1N338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N338" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "F1N338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N338" } ] } ] }, { "uniprot_ac": "G3MWG4", "gene_name": "IARS2", "activity": [ { "ec_number": "6.1.1.5", "activity": "tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate.", "evidence": [ { "id": "G3MWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ] }, { "ec_number": "6.1.1.5", "activity": "", "evidence": [ { "id": "G3MWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ] } ] }, { "uniprot_ac": "G3MWN1", "gene_name": "ARG2", "activity": [ { "ec_number": "3.5.3.1", "activity": "L-arginine + H2O = urea + L-ornithine.", "evidence": [ { "id": "G3MWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWN1" } ] }, { "ec_number": "3.5.3.1", "activity": "", "evidence": [ { "id": "G3MWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWN1" } ] } ] }, { "uniprot_ac": "G3N0R5", "gene_name": "HSPD1", "activity": [ { "ec_number": "5.6.1.7", "activity": "ATP + H2O + an unfolded polypeptide = ADP + phosphate + a folded polypeptide.", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ] }, { "ec_number": "5.6.1.7", "activity": "", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ] } ] }, { "uniprot_ac": "O02691", "gene_name": "HSD17B10", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.239", "activity": "testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.178", "activity": "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methyl-3-oxobutanoyl-CoA + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.53", "activity": "androstan-3alpha,17beta-diol + NAD(+) = 17beta-hydroxyandrostanone + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.159", "activity": "cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] } ] }, { "uniprot_ac": "P00829", "gene_name": "ATP5F1B", "activity": [ { "ec_number": "7.1.2.2", "activity": "ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out).", "evidence": [ { "id": "P00829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00829" } ] }, { "ec_number": "7.1.2.2", "activity": "", "evidence": [ { "id": "P00829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00829" } ] } ] }, { "uniprot_ac": "P11181", "gene_name": "DBT", "activity": [ { "ec_number": "2.3.1.168", "activity": "(2S)-2-methylbutanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = 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"comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R6W2-1", "uniprot_ac": "F6R6W2", "uniprot_id": "F6R6W2_BOVIN", "mass": { "chemical_mass": 105068.0, "monoisotopic_mass": 105068.0 }, "refseq": {}, "gene_names": [ { "name": "DDX23", "type": "recommended", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DDX23", "type": "recommended", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2/entry#names_and_taxonomy" } ] }, { "name": "DEAD box protein 23", "type": "synonym", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation. Independently of its spliceosome formation function, required for the suppression of incorrect R-loops formed during transcription; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T327", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T327#function" }, { "database": "UniProtKB", "id": "ARBA00055288", "url": "https://www.uniprot.org/uniprotkb/ARBA00055288#function" }, { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DDX23", "url": "https://www.uniprot.org/uniprotkb/F6R6W2", "locus": { "chromosome": "5", "start_pos": 30948936, "end_pos": 30933997, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021810", "url": "https://www.ensembl.org/id/ENSBTAG00000021810" } ] } } ], "crossref": [ { "id": "F6R6W2", "url": "https://alphafold.ebi.ac.uk/entry/F6R6W2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17945", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17945", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25430", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25430", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T327", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T327", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T327-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T327-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R6W2-1", "url": "https://www.uniprot.org/uniprotkb/F6R6W2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNSCSHRLKCLTNHIAQRPPRPGTSARAVHSGIGSSRPCVVGLRCPGPGTRLPGLPRGRGSSPATRKRERWRLLGDVEAALGGLGSRVMAGELADKKDRDASPSKEERKRSRTPDRDRDRDRDRKSSPSKDRKRHRSRDRRRGVSRSRSRSRSKSTERDRRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSRKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "length": 909, "header": "tr|F6R6W2-1|F6R6W2_BOVIN Isoform 1 of Probable ATP-dependent RNA helicase DDX23 OS=Bos taurus OX=9913 GN=DDX23 PE=3 SV=1 CANONICAL=F6R6W2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T327-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T327/entry", "sequence": { "sequence": "MAGELADKKDRDASPSKEERKRSRTPDRDRDRDRDRKSSPSKDRKRHRSRDRRRGVSRSRSRSRSKSTESLSPGRGKDFKSRKDRDSRKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "length": 783, "header": "tr|A0AAA9T327-1|F6R6W2_BOVIN Computationally mapped isoform of Probable ATP-dependent RNA helicase DDX23 OS=Bos taurus OX=9913 GN=DDX23 PE=3 SV=1 CANONICAL=F6R6W2-1" }, "locus": { "chromosome": "5", "start_pos": 30948260, "end_pos": 30939336, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090250.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090250.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093185.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093185.1" } ] } }, { "isoform_ac": "F6R6W2-1", "url": "https://www.uniprot.org/uniprotkb/F6R6W2/entry", "sequence": { "sequence": "MKNSCSHRLKCLTNHIAQRPPRPGTSARAVHSGIGSSRPCVVGLRCPGPGTRLPGLPRGRGSSPATRKRERWRLLGDVEAALGGLGSRVMAGELADKKDRDASPSKEERKRSRTPDRDRDRDRDRKSSPSKDRKRHRSRDRRRGVSRSRSRSRSKSTERDRRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSRKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA", "length": 909, "header": "tr|F6R6W2-1|F6R6W2_BOVIN Isoform 1 of Probable ATP-dependent RNA helicase DDX23 OS=Bos taurus OX=9913 GN=DDX23 PE=3 SV=1 CANONICAL=F6R6W2-1" }, "locus": { "chromosome": "5", "start_pos": 30948260, "end_pos": 30934146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029071.6", "url": "https://www.ensembl.org/id/ENSBTAT00000029071.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029071.5", "url": "https://www.ensembl.org/id/ENSBTAP00000029071.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "F6R6W2", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", 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"gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { 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} ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate 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"https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ 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"5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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{ "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { 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ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0IIK5", "database": 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RNA.", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] } ] }, { "uniprot_ac": "Q0VCX2", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] } ] }, { "uniprot_ac": "Q0VD48", "gene_name": "VPS4B", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] } ] }, { "uniprot_ac": "Q17R09", "gene_name": "DHX38", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q17R09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R09" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q17R09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R09" } ] } ] }, { "uniprot_ac": "Q1LZ78", "gene_name": "NTPCR", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "Q1LZ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZ78" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "Q1LZ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZ78" } ] } 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"evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] } ] }, { "uniprot_ac": "Q2NKY8", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] } ] }, { "uniprot_ac": "Q2NKZ1", "gene_name": "CCT7", "activity": [ { "ec_number": "3.6.1.-", 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"categories": [ "Protein" ] }, { "id": "G3MXS7", "url": "https://www.uniprot.org/uniprotkb/G3MXS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXS7-1", "url": "https://www.uniprot.org/uniprotkb/G3MXS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRLLEPCWWILFLKITSSVLHYVVCFPALTEGYVGTLHENRQGSSVQAQIRRRKASGDPYWAYSGAYGPEYWVTSSVSCGGRQQSPIDISDQHARVSEEYQDLQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAVFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQGLNNRVVYKSAIRDAWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMVSYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFSGGGISSFPSTVWPTRLPTAASASKQAGRPVLATTEALASPGADGDSAPSKDGEGAEESEKDEKSESEDGEREHEEEGEKDSEKKERSGVTHAPRARNHTQPTAAPSAPGTVAQEGAHQTTSGRERARTAIPTARPQDALDPLSVTPTQVPPTVTEEQDEDSDPARPEMPSRKPVPPGDRFPEDSRFITVNPAEKNTSGMISRPSPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKVHACYTVRHFSVRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARTPEMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVSTKENGNGPMTVDRNGAALTADESDPAESMESLV", "length": 1442, "header": "tr|G3MXS7-1|G3MXS7_BOVIN Isoform 1 of Receptor-type tyrosine-protein phosphatase gamma OS=Bos taurus OX=9913 GN=PTPRG PE=3 SV=3 CANONICAL=G3MXS7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0H5/entry", "sequence": { "sequence": "MRRLLEPCWWILFLKITSSVLHYVVCFPGAYGPEYWVTSSVSCGGRQQSPIDISDQHARVSEEYQDLQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAVFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQGLNNRVVYKSAIRDAWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMVSYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFSGGGISSFPSTVWPTRLPTAASASKQAGRPVLATTEALASPGADGDSAPSKDGEGAEESEKDEKSESEDGEREHEEEGEKDSEKKERSGVTHAPRARNHTQPTAAPSAPGTVAQEGAHQTTSGRERARTAIPTARPQDALDPLSVTPTQVPPTVTEEQDEDSDPARPEMPSRKPVPPGDRFPEDSRFITVNPAEKNTSGMISRPSPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKVHACYTVRHFSVRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARTPEMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVSTKENGNGPMTVDRNGAALTADESDPAESMESLV", "length": 1376, "header": "tr|A0A3Q1M0H5-1|A0A3Q1M0H5_BOVIN Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase gamma OS=Bos taurus OX=9913 GN=PTPRG PE=3 SV=2 CANONICAL=G3MXS7-1" }, "locus": { "chromosome": "22", "start_pos": 39798524, "end_pos": 39029169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085648.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085648.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061482.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061482.2" } ] } }, { "isoform_ac": "A0AAA9TG30-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG30/entry", "sequence": { "sequence": "MRRLLEPCWWILFLKITSSVLHYVVCFPALTEGYVGTLHENRQGSSVQAQIRRRKASGDPYWAYSGAYGPEYWVTSSVSCGGRQQSPIDISDQHARVSEEYQDLQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAVFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQGLNNRVVYKSAIRDAWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMVSYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFSGGGISSFPSTVWPTRLPTAASASKQAGRPVLATTEALASPGADGDSAPSKDGEGAEESEKDEKSESEDGEREHEEEGEKDSEKKERSGVTHAPRARNHTQPTAAPSAPGTVAQEGAHQTTSGRERARTAIPTARPQDALDPLSVTPTQVPPTVTEEQDEDSDPARPEMPSRKPVPPGDRFPEDSRFITVNPAEKNTSGMISRPSPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKVHACYTVRHFSVRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARTPEMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVSTKENGNGPMTVDRNGAALTADESDPAESMESLV", "length": 1413, "header": "tr|A0AAA9TG30-1|G3MXS7_BOVIN Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase gamma OS=Bos taurus OX=9913 GN=PTPRG PE=3 SV=1 CANONICAL=G3MXS7-1" }, "locus": { "chromosome": "22", "start_pos": 39798524, "end_pos": 39029169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116701.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116701.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095805.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095805.1" } ] } }, { "isoform_ac": "F1MFJ3-1", "url": "https://www.uniprot.org/uniprotkb/F1MFJ3/entry", "sequence": { "sequence": "MDQEAHFHCFYGLERFWGVYPSKYLSTFRNHQIRETQSGAYGPEYWVTSSVSCGGRQQSPIDISDQHARVSEEYQDLQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAVFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQGLNNRVVYKSAIRDAWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMVSYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFSGGGISSFPSTVWPTRLPTAASASKQAGRPVLATTEALASPGADGDSAPSKDGEGAEESEKDEKSESEDGEREHEEEGEKDSEKKERSGVTHAPRARNHTQPTAAPSAPGTVAQEGAHQTTSGRERARTAIPTARPQDALDPLSVTPTQVPPTVTEEQDEDSDPARPEMPSRKPVPPGDRFPEDSRFITVNPAEKNTSGMISRPSPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKVHACYTVRHFSVRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARTPEMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVSTKENGNGPMTVDRNGAALTADESDPAESMESLV", "length": 1415, "header": "tr|F1MFJ3-1|F1MFJ3_BOVIN Computationally mapped isoform of Receptor-type tyrosine-protein phosphatase gamma OS=Bos taurus OX=9913 GN=PTPRG PE=3 SV=4 CANONICAL=G3MXS7-1" }, "locus": { "chromosome": "22", "start_pos": 39524071, "end_pos": 39029169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029213.7", "url": "https://www.ensembl.org/id/ENSBTAT00000029213.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029213.7", "url": "https://www.ensembl.org/id/ENSBTAP00000029213.7" } ] } }, { "isoform_ac": "G3MXS7-1", "url": "https://www.uniprot.org/uniprotkb/G3MXS7/entry", "sequence": { "sequence": "MRRLLEPCWWILFLKITSSVLHYVVCFPALTEGYVGTLHENRQGSSVQAQIRRRKASGDPYWAYSGAYGPEYWVTSSVSCGGRQQSPIDISDQHARVSEEYQDLQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAVFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFILRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQGLNNRVVYKSAIRDAWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMVSYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFSGGGISSFPSTVWPTRLPTAASASKQAGRPVLATTEALASPGADGDSAPSKDGEGAEESEKDEKSESEDGEREHEEEGEKDSEKKERSGVTHAPRARNHTQPTAAPSAPGTVAQEGAHQTTSGRERARTAIPTARPQDALDPLSVTPTQVPPTVTEEQDEDSDPARPEMPSRKPVPPGDRFPEDSRFITVNPAEKNTSGMISRPSPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKVHACYTVRHFSVRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARTPEMGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSSQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVSTKENGNGPMTVDRNGAALTADESDPAESMESLV", "length": 1442, "header": "tr|G3MXS7-1|G3MXS7_BOVIN Isoform 1 of Receptor-type tyrosine-protein phosphatase gamma OS=Bos taurus OX=9913 GN=PTPRG PE=3 SV=3 CANONICAL=G3MXS7-1" }, "locus": { "chromosome": "22", "start_pos": 39798524, "end_pos": 39029169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063448.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063448.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054347.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054347.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MXS7", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "G3MXS7", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3MXS7", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of epithelial cell migration", "id": "GO:0010633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010633", "evidence": [ { "database": "UniProtKB", "id": "G3MXS7", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3MXS7", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "G3MXS7", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1178, "end_pos": 1180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1249, "end_pos": 1251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 860, "end_pos": 862, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1ME76-1", "F1MRH9-1", "A0AAF6DLF7-1", "A0AAA9S9Q3-1", "E1BFE2-1", "E1BL76-1", "G3MXS7-1", "A0A3Q1LUB1-1", "A0AAA9THG9-1", "F1N339-1", "F6RY99-1", "A0AAF6YUC8-1", "A0AAA9RTM1-1", "A0AAA9SMJ6-1", "A0A3Q1LZA9-1", "A7MBD1-1", "A5D7P0-1", "Q58DB6-1", "A0AAA9SEK4-1", "E1BDH9-1", "F1MGK4-1", "E1BIH4-1", "A0A3Q1M6K1-1", "E1BIU8-1", "A7MBJ4-1", "A6H730-1", "A0A3Q1MFX2-1", "A0AAA9U0H6-1", "A2VDT1-1", "E1BPU9-1", "P0C591-1", "P11064-1", "Q0IID7-1", "Q2KJ36-1", "Q2T9S4-1", "E1BPA0-1", "A0AAA9TAZ9-1", "Q5BIP9-1", "A0A3Q1M5K4-1", "F1MM08-1", "E1BJR7-1", "Q17QJ3-1", "Q17QM8-1", "F1MD22-1", "F1MI99-1", "F1MP34-1", "F1MGK5-1", "F1MEZ2-1", "F1MQM7-1", "E1BEZ8-1", "A0A3Q1M0B4-1", "A0AAA9S7W5-1", "A0A3Q1N8V6-1", "A0AAA9TFV5-1", "A0A3Q1MBB1-1", "F1MTZ3-1", "A0AAF6Z8C2-1", "F1MDF1-1", "A0AAA9T5N9-1", "E1BKT4-1", "A0A3Q1MH98-1", "F1N6L3-1", "F1MW70-1", "F1MXF2-1", "A0AAA9TWD1-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LUB1", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] } ] }, { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B4", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] } ] }, { "uniprot_ac": "A0A3Q1M5K4", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1MBB1", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] } ] }, { "uniprot_ac": "A0A3Q1MFX2", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S7W5", "gene_name": "PTPRV", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] } ] }, { "uniprot_ac": "A0AAA9S9Q3", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] } ] }, { "uniprot_ac": "A0AAA9SEK4", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] } ] }, { "uniprot_ac": "A0AAA9SMJ6", "gene_name": "PTPRH", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAA9TAZ9", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] } ] }, { "uniprot_ac": "A0AAA9TFV5", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] } ] }, { "uniprot_ac": "A0AAA9THG9", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] } ] }, { "uniprot_ac": "A0AAA9TWD1", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YUC8", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A2VDT1", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] } ] }, { "uniprot_ac": "A5D7P0", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7MBJ4", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] } ] }, { "uniprot_ac": "E1BDH9", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] } ] }, { "uniprot_ac": "E1BEZ8", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "E1BIH4", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] } ] }, { "uniprot_ac": "E1BIU8", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] } ] }, { "uniprot_ac": "E1BJR7", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] } ] }, { "uniprot_ac": "E1BKT4", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ] }, { "uniprot_ac": "E1BL76", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPU9", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] } ] }, { "uniprot_ac": "F1MD22", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] } ] }, { "uniprot_ac": "F1MDF1", "gene_name": "PTPN18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MGK4", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] } ] }, { "uniprot_ac": "F1MGK5", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MRH9", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] } ] }, { "uniprot_ac": "F1MTZ3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1MXF2", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] } ] }, { "uniprot_ac": "F1N339", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] } ] }, { "uniprot_ac": "F1N6L3", "gene_name": "PTPN22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] } ] }, { "uniprot_ac": "F6RY99", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O 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"url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P11064", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { "uniprot_ac": "Q17QJ3", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] } ] }, { "uniprot_ac": "Q17QM8", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] } ] }, { "uniprot_ac": "Q2KJ36", "gene_name": "DUSP6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": 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] }, { "ec_number": "3.1.3.18", "activity": "", "evidence": [ { "id": "Q2T9S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9S4" } ] } ] }, { "uniprot_ac": "Q58DB6", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q58DB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DB6" } ] } ] }, { "uniprot_ac": "Q5BIP9", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 323, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 351, "end_pos": 450, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 1033, "end_pos": 1107, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" }, { "id": "PS50055", "database": "PROSITE", "url": 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}, { "start_pos": 1178, "end_pos": 1180 }, { "start_pos": 1204, "end_pos": 1206 }, { "start_pos": 1249, "end_pos": 1251 }, { "start_pos": 158, "end_pos": 160 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 810, "end_pos": 812 }, { "start_pos": 860, "end_pos": 862 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E563-1", "uniprot_ac": "G5E563", "uniprot_id": "G5E563_BOVIN", "mass": { "chemical_mass": 66299.0, "monoisotopic_mass": 66299.0 }, "refseq": { "ac": "XP_005210803", "name": "zinc finger-containing ubiquitin peptidase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803" }, "gene_names": [ { "name": "ZUP1", "type": "recommended", "evidence": [ { "id": "G5E563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ] }, { "name": "C6orf113", "type": "synonym", "evidence": [ { "id": "XP_005210803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803" } ] }, { "name": "C9H6orf113", "type": "synonym", "evidence": [ { "id": "XP_005210803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803" } ] }, { "name": "DUB", "type": "synonym", "evidence": [ { "id": "XP_005210803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803" } ] }, { "name": "ZUFSP", "type": "synonym", "evidence": [ { "id": "XP_005210803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803" } ] }, { "name": "ZUP1", "type": "synonym", "evidence": [ { "id": "XP_005210803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803" } ] } ], "protein_names": [ { "name": "Zinc finger-containing ubiquitin peptidase 1", "type": "recommended", "evidence": [ { "id": "G5E563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E563/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "G5E563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E563/entry#names_and_taxonomy" } ] }, { "name": "Lys-63-specific deubiquitinase ZUFSP", "type": "synonym", "evidence": [ { "id": "G5E563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E563/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger with UFM1-specific peptidase domain protein", "type": "synonym", "evidence": [ { "id": "G5E563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E563/entry#names_and_taxonomy" } ] }, { "name": "zinc finger-containing ubiquitin peptidase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005210803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803" } ] } ], "function": [ { "annotation": "Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TGL3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGL3#function" }, { "database": "UniProtKB", "id": "ARBA00045669", "url": "https://www.uniprot.org/uniprotkb/ARBA00045669#function" }, { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563#function" }, { "database": "UniProtKB", "id": "A0ABI0P1G5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZUP1", "url": "https://www.uniprot.org/uniprotkb/G5E563", "locus": { "chromosome": "9", "start_pos": 33949379, "end_pos": 33924603, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003878", "url": "https://www.ensembl.org/id/ENSBTAG00000003878" } ] } } ], "crossref": [ { "id": "G5E563", "url": "https://alphafold.ebi.ac.uk/entry/G5E563", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003878", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003878", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533724", "url": "https://www.ncbi.nlm.nih.gov/gene/533724", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HHTGYNE", "url": "https://omabrowser.org/oma/group/HHTGYNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E563", "url": "https://www.orthodb.org/?gene=G5E563", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005210803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210803", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SIT0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGL3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1G5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1G5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E563-1", "url": "https://www.uniprot.org/uniprotkb/G5E563-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSCDICGETVSSEPDMKAHLLIVHMENEVICPFCKLSGVNYDEMCFHIETAHFEQNELERNFERINTVQYGISDNRKDSSLQCRADINSSVHSACASNQPKISAQSLPKDGTLKHKDFYSENLTESRKFLKSTEKQSDRTKIKESIYETMYSPPECPFCGKIEDNSQDMETHVKTKHADLLDTPLEDCNQLLYDCPMCGLVCTNYHILQEHVDLHLEESSFGQGVNRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMHPSEFHRRKADMMESLAIGVDDGKTKTSGIMEALYRYYQNAATDVRRVWLSAGVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDAYDDSLKGMSVPCIPKIQSMIEDAWKEGFDPQGASQLNDKLQGTKAWIGACEIYTLLTSLRIKCRIVDFHESTGPLGTHPRLFEWILSYYASEREGSPKVVCTSKPPIYLQHQGHSRTVVGIEEKKNRTLCLLVFDPGCPSREMQKLLKQDMEVSSLKQLRKFVGNLKHKQYQIVAVEGVLSSEEKIARRQASQVFTAEKIP", "length": 579, "header": "tr|G5E563-1|G5E563_BOVIN Isoform 1 of Zinc finger-containing ubiquitin peptidase 1 OS=Bos taurus OX=9913 GN=ZUP1 PE=3 SV=2 CANONICAL=G5E563-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SIT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIT0/entry", "sequence": { "sequence": "MLSCDICGETVSSEPDMKAHLLIVHMENEVICPFCKLSGVNYDEMCFHIETAHFEQNELERNFERINTVQYGISDNRKDSSLQCRADINSSVHSACASNQPKISAQSLPKDGTLKHKDFYSENLTESRKFLKSTEKQSDRTKIKESIYETMYSPPECPFCGKIEDNSQDMETHVKTKHADLLDTPLEDCNQLLYDCPMCGLVCTNYHILQEHVDLHLEESSFGQGVNRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFQKLQELWKHFIGIIRMLPQM", "length": 281, "header": "tr|A0AAA9SIT0-1|G5E563_BOVIN Computationally mapped isoform of Zinc finger-containing ubiquitin peptidase 1 OS=Bos taurus OX=9913 GN=ZUP1 PE=3 SV=1 CANONICAL=G5E563-1" }, "locus": { "chromosome": "9", "start_pos": 33940094, "end_pos": 33926747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117812.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117812.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085244.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085244.1" } ] } }, { "isoform_ac": "A0AAA9TGL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGL3/entry", "sequence": { "sequence": "MLSCDICGETVSSEPDMKAHLLIVHMENEVICPFCKLSGVNYDEMCFHIETAHFEQNELERNFERINTVQYGISDNRKDSSLQCRADINSSVHSACASNQPKISAQSLPKDGTLKHKDFYSENLTESRKFLKSTEKQSDRTKIKESIYETMYSPPECPFCGKIEDNSQDMETHVKTKHADLLDTPLEGVNRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMHPSEFHRRKADMMESLAIGVDDGKTKTSGIMEALYRYYQNAATDVRRVWLSAGVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDAYDDSLKGMSVPCIPKIQSMIEDAWKEGFDPQGASQLNDKLQGTKAWIGACEIYTLLTSLRIKCRIVDFHESTGPLGTHPRLFEWILSYYASEREGSPKVVCTSKPPIYLQHQGHSRTVVGIEEKKNRTLCLLVFDPGCPSREMQKLLKQDMEVSSLKQLRKFVGNLKHKQYQIVAVEGVLSSEEKIARRQASQVFTAEKIP", "length": 542, "header": "tr|A0AAA9TGL3-1|G5E563_BOVIN Computationally mapped isoform of Zinc finger-containing ubiquitin peptidase 1 OS=Bos taurus OX=9913 GN=ZUP1 PE=3 SV=1 CANONICAL=G5E563-1" }, "locus": { "chromosome": "9", "start_pos": 33949183, "end_pos": 33926747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125328.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125328.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095331.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095331.1" } ] } }, { "isoform_ac": "A0ABI0P1G5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G5/entry", "sequence": { "sequence": "MLSCDICGETVSSEPDMKAHLLIVHMENEVICPFCKLSGVNYDEMCFHIETAHFEQNELERNFERINTVQYGISDNRKDSSLQCRADINSSVHSACASNQPKISAQSLPKDGTLKHKDFYSENLTESRKFLKSTEKQSDRTKIKESIYETMYSPPECPFCGKIEDNSQDMETHVKTKHADLLDTPLEDCNQLLYDCPMCGLVCTNYHILQEHVDLHLEESSFGQGVNRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMHPSEFHRRKADMMESLAIGVDDGKTKTSGIMEALYRYYQNAATDVRRVWLSAGVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDAYDDSLKGMSVPCIPKIQSMIEDAWKEGFDPQGASQLNDKLQGTKAWIGACEIYTLLTSLRIKCRIVDFHESTGPLGTHPRLFEWILSYYASEREGSPKVVCTSKPPIYLQHQGHSRTVVGIEEKKNRTLCLLVFDPGCPSREMQKLLKQDMEVSSLKQLRKFVGNLKHKQYQIVAVEGVLSSEEKIVSI", "length": 567, "header": "tr|A0ABI0P1G5-1|A0ABI0P1G5_BOVIN Computationally mapped isoform of Zinc finger-containing ubiquitin peptidase 1 OS=Bos taurus OX=9913 GN=ZUP1 PE=3 SV=1 CANONICAL=G5E563-1" }, "locus": { "chromosome": "9", "start_pos": 33945451, "end_pos": 33926747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145727.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145727.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106835.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106835.1" } ] } }, { "isoform_ac": "G5E563-1", "url": "https://www.uniprot.org/uniprotkb/G5E563/entry", "sequence": { "sequence": "MLSCDICGETVSSEPDMKAHLLIVHMENEVICPFCKLSGVNYDEMCFHIETAHFEQNELERNFERINTVQYGISDNRKDSSLQCRADINSSVHSACASNQPKISAQSLPKDGTLKHKDFYSENLTESRKFLKSTEKQSDRTKIKESIYETMYSPPECPFCGKIEDNSQDMETHVKTKHADLLDTPLEDCNQLLYDCPMCGLVCTNYHILQEHVDLHLEESSFGQGVNRVQCSRDLELAQQLQQEEDRKRRSEESRQEMEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMHPSEFHRRKADMMESLAIGVDDGKTKTSGIMEALYRYYQNAATDVRRVWLSAGVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNDAYDDSLKGMSVPCIPKIQSMIEDAWKEGFDPQGASQLNDKLQGTKAWIGACEIYTLLTSLRIKCRIVDFHESTGPLGTHPRLFEWILSYYASEREGSPKVVCTSKPPIYLQHQGHSRTVVGIEEKKNRTLCLLVFDPGCPSREMQKLLKQDMEVSSLKQLRKFVGNLKHKQYQIVAVEGVLSSEEKIARRQASQVFTAEKIP", "length": 579, "header": "tr|G5E563-1|G5E563_BOVIN Isoform 1 of Zinc finger-containing ubiquitin peptidase 1 OS=Bos taurus OX=9913 GN=ZUP1 PE=3 SV=2 CANONICAL=G5E563-1" }, "locus": { "chromosome": "9", "start_pos": 33949183, "end_pos": 33926747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005061.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005061.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005061.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005061.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1QAX5-1", "protein_name": "Zinc finger-containing ubiquitin peptidase 1", "gene_name": "zufsp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPVCDICCEELLSEAEMKTHLLLSHMENLMACPFCSLSGVSYDELSFHINTAHTDKDYQDTNVTMVNSGQKNDCITKSTSNVNATNTCKASHQLLPQVNGTATQITGTSHSQGPSASRKSSPPAAATANGAIKLVRTTQTPSNYTRRKSEDGHQKSKQKRLSSPFKEGCFPCPMCNLVYSDCFALQEHVEIHLQDQDAGTGSDVETLTKISAESNDRAGGMRYECPMCSLRCSCSSSLQEHVELHLEYSSASATGHSPGEDLTLARKLQEEEEQNWREVQTRREAEDFKKLQKQFGLDNSGGYRKQMERNLDRAVSRGQMLPADFHRKRAEMLESLASGVDDGRSKTSGLMEALYRYYQRDASDCAHVWLCAETDHYSSSEGDKGWGCGYRNFQMLLSSLHRMEQYKHLPVSVPSIPRVQALMEEAWAQGADPQGASHFNNRLQGTRAWIGATEIYAVLTSLSVKARIVDFHKPTGPRETHPRLFEWVKQYFTHSTSRGARLPPKVVQTTLPPVYLQHQGHSRSIIGMEEKANGKLCLLFFDPGVTPAEMKKVLSQDTVTSMVQRMRKYTSGLKHKQYQVVIVEGVLTAEEKQSRILNSRTLRAEKIP", "length": 608 }, "evidence": [ { "id": "G5E563", "url": "https://omabrowser.org/oma/group/G5E563/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G5E563", "url": "https://www.uniprot.org/uniprotkb/G5E563" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E563-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 579, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E563-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E563" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E563" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 221, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYG6-1", "uniprot_ac": "G3MYG6", "uniprot_id": "G3MYG6_BOVIN", "mass": { "chemical_mass": 48745.0, "monoisotopic_mass": 48745.0 }, "refseq": { "ac": "NP_001137564", "name": "zinc transporter ZIP6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137564" }, "gene_names": [ { "name": "SLC39A6", "type": "recommended", "evidence": [ { "id": "G3MYG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYG6" } ] }, { "name": "SLC39A6", "type": "synonym", "evidence": [ { "id": "NP_001137564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001137564" } ] } ], 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"tr|G3MYG6-1|G3MYG6_BOVIN Isoform 1 of Zinc transporter ZIP6 OS=Bos taurus OX=9913 GN=SLC39A6 PE=3 SV=1 CANONICAL=G3MYG6-1" }, "locus": { "chromosome": "24", "start_pos": 21026637, "end_pos": 21011192, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065246.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065246.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054598.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054598.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524456", "resource": "KEGG Pathway" }, { "id": "R-BTA-442380", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-442380", "resource": "Reactome", "description": "Zinc influx into cells by the SLC39 gene family" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "G3MYG6", "url": "https://www.uniprot.org/uniprotkb/G3MYG6" } ], "pmid": "" }, { "name": "monoatomic cation:bicarbonate symporter activity", "id": "GO:0140410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140410", "evidence": [ { "database": "UniProtKB", "id": "G3MYG6", "url": "https://www.uniprot.org/uniprotkb/G3MYG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "lymphocyte activation", "id": "GO:0046649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046649", "evidence": [ { "database": "UniProtKB", "id": "G3MYG6", "url": "https://www.uniprot.org/uniprotkb/G3MYG6" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": 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"url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "50596", "url": "https://www.rhea-db.org/rhea/50596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50600", "url": "https://www.rhea-db.org/rhea/50600", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S3E6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3E6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWG1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6REB9-1", "url": "https://www.uniprot.org/uniprotkb/F6REB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIDTAWREGGGPWLTSFLARHLLRVSRLFLVCEPLGPPPRLSTCVPYPRPSFRGALRRRGSRRGALGSPRGACAVRGRPPLQCRRYCRLPAGKCGKEELSATAAVVAMGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMRTMYEQSEWGWKDREKREEMTDDRAWYLIAWENRSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSQHSHSGGHCGGCCH", "length": 345, "header": "tr|F6REB9-1|F6REB9_BOVIN Isoform 1 of N-alpha-acetyltransferase 40 OS=Bos taurus OX=9913 GN=NAA40 PE=3 SV=1 CANONICAL=F6REB9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3E6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3E6/entry", "sequence": { "sequence": "MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSQHSHSGGHCGGCCH", "length": 124, "header": "tr|A0AAA9S3E6-1|F6REB9_BOVIN Computationally mapped isoform of N-alpha-acetyltransferase 40 OS=Bos taurus OX=9913 GN=NAA40 PE=3 SV=1 CANONICAL=F6REB9-1" }, "locus": { "chromosome": "29", "start_pos": 42293350, "end_pos": 42281654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131477.2", "url": "https://www.ensembl.org/id/ENSBTAT00000131477.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080455.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080455.1" } ] } }, { "isoform_ac": "A0AAA9TWG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWG1/entry", "sequence": { "sequence": "MGSCRSRAGTRLPCTGRQTPNHWTPREAYQFLHRRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMRTMYEQSEWGWKDREKREEMTDDRAWYLIAWENRSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSQHSHSGGHCGGCCH", "length": 269, "header": "tr|A0AAA9TWG1-1|F6REB9_BOVIN Computationally mapped isoform of N-alpha-acetyltransferase 40 OS=Bos taurus OX=9913 GN=NAA40 PE=3 SV=1 CANONICAL=F6REB9-1" }, "locus": { "chromosome": "29", "start_pos": 42293350, "end_pos": 42286860, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107690.2", "url": "https://www.ensembl.org/id/ENSBTAT00000107690.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101519.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101519.1" } ] } }, { "isoform_ac": "F6REB9-1", "url": "https://www.uniprot.org/uniprotkb/F6REB9/entry", "sequence": { "sequence": "MAIDTAWREGGGPWLTSFLARHLLRVSRLFLVCEPLGPPPRLSTCVPYPRPSFRGALRRRGSRRGALGSPRGACAVRGRPPLQCRRYCRLPAGKCGKEELSATAAVVAMGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMRTMYEQSEWGWKDREKREEMTDDRAWYLIAWENRSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSQHSHSGGHCGGCCH", "length": 345, "header": "tr|F6REB9-1|F6REB9_BOVIN Isoform 1 of N-alpha-acetyltransferase 40 OS=Bos taurus OX=9913 GN=NAA40 PE=3 SV=1 CANONICAL=F6REB9-1" }, "locus": { "chromosome": "29", "start_pos": 42293350, "end_pos": 42281330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003996.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003996.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003996.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003996.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "histone H4 acetyltransferase activity", "id": "GO:0010485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010485", "evidence": [ { "database": "UniProtKB", "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ], "pmid": "" }, { "name": "histone H2A acetyltransferase activity", "id": "GO:0043998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043998", "evidence": [ { "database": "UniProtKB", "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ], "pmid": "" }, { "name": "protein N-terminal-serine acetyltransferase activity", "id": "GO:1990189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990189", "evidence": [ { "database": "UniProtKB", "id": "F6REB9", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "50596", "name": "", "equation": "N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6REB9-1" ], "evidence": [ { "id": "50596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50596" } ] }, { "id": "50600", "name": "", "equation": "N-terminal L-seryl-[histone H2A] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6REB9-1" ], "evidence": [ { "id": "50600", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50600" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F6REB9", "gene_name": "NAA40", "activity": [ { "ec_number": "2.3.1.257", "activity": "N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+).", "evidence": [ { "id": "F6REB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ] }, { "ec_number": "2.3.1.257", "activity": "", "evidence": [ { "id": "F6REB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REB9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6REB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REB9" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 324, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.257", "ec_name": "N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+).", "evidence": [ { "id": "2.3.1.257", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.257" }, { "id": "2.3.1.257", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.257" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 272, "end_pos": 274 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXC8-1", "uniprot_ac": "G3MXC8", "uniprot_id": "G3MXC8_BOVIN", "mass": { "chemical_mass": 16599.0, "monoisotopic_mass": 16599.0 }, "refseq": {}, "gene_names": [ { "name": "ARPC5", "type": "recommended", "evidence": [ { "id": "G3MXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXC8" } ] } ], "protein_names": [ { "name": "Actin-related protein 2/3 complex subunit 5", "type": "recommended", 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"url": "https://www.uniprot.org/uniprotkb/A0AAA9TE51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE51-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U051", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U051", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U051-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U051-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MW47", "url": "https://www.uniprot.org/uniprotkb/F1MW47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MW47-1", "url": "https://www.uniprot.org/uniprotkb/F1MW47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N150", "url": "https://www.uniprot.org/uniprotkb/G3N150", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N150-1", "url": "https://www.uniprot.org/uniprotkb/G3N150-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNKIILLLSLQISLLGTTFGGNVLIWPMEGSHWLNIKTIIDELIKKGHNVTVLVASSAFCITPTTNPSLIFEIYEVPFGKERIEGVIKDFILTWMEHRPSPLTIWRFYQEMAKVIKDFHMVSREICDSVLQNEKLMEKLKKSKFEVLVSDPVFPCGDIIALKLGIPFIYSLRFSPASTVEKHCGKVPYPPSYVPAILSELTDQMSFTDRIRNFISYHLQDYMFNTLWKSWDSYYSKALGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEDGIVVFSLGSMVKNLTEEKANRIASALAQIPQKVLWRYKGKKPATLGANTRLYDWIPQNDLLGHPKAKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNINTMTSADLLNALRTVINEPSYKENAMRLKRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHNLTWYQYHSLDVIGFLLACVATAVFLVTRCCLFSCRKFGKTGKKKKRE", "length": 528, "header": "tr|G3N150-1|G3N150_BOVIN Isoform 1 of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=UGT2A1 PE=3 SV=2 CANONICAL=G3N150-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TE51-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE51/entry", "sequence": { "sequence": "MVSIMDVTIPKKFYHHLIFNLTLIEIVLSGNVLIWPTDGSHWLNIKIILEELNQRNHNVTVLASSATLFINSNSDSPVNFEVIPVSYKKSNIDSLIEHMIMLWIDHRPTPLTLWTFYKELGKLLDTFFRINIQICDGVLNNPKLMARLWKSRFDVLLADPVTICGDLVALKLGIPFMYTLRFSPASTVERHCGKIPAPASYVPAALSELTDQMSFGERLKNTISYPLQDYIFQSYWGEWNSYYSKVLGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEDGIVVFSLGSMVKNLTEEKANRIASALAQIPQKVLWRYKGKKPATLGANTRLYDWIPQNDLLGHPKAKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNINTMTSADLLNALRTVINEPSYKENAMRLKRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHNLTWYQYHSLDVIGFLLACVATAVFLVTRCCLFSCRKFGKTGKKKKRE", "length": 536, "header": "tr|A0AAA9TE51-1|G3N150_BOVIN Computationally mapped isoform of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=UGT2A1 PE=3 SV=1 CANONICAL=G3N150-1" }, "locus": { "chromosome": "6", "start_pos": 85122493, "end_pos": 85084583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091581.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091581.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095185.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095185.1" } ] } }, { "isoform_ac": "A0AAA9U051-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U051/entry", "sequence": { "sequence": "MLNKIILLLSLQISLLGTTFGGNVLIWPMEGSHWLNIKTIIDELIKKGHNVTVLVASSAFCITPTTNPSLIFEIYEVPFGKERIEGVIKDFILTWMEHRPSPLTIWRFYQEMAKVIKDFHMVSREICDSVLQNEKLMEKLKKSKFEVLVSDPVFPCGDIIALKLGIPFIYSLRFSPASTVEKHCGKVPYPPSYVPAILSELTDQMSFTDRIRNFISYHLQDYMFNTLWKSWDSYYSKALGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKVLWRYKGKKPATLGANTRLYDWIPQNDLLGHPKAKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNINTMTSADLLNALRTVINEPSYKENAMRLKRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHNLTWYQYHSLDVIGFLLACVATAVFLVTRCCLFSCRKFGKTGKKKKRE", "length": 484, "header": "tr|A0AAA9U051-1|G3N150_BOVIN Computationally mapped isoform of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=UGT2A1 PE=3 SV=1 CANONICAL=G3N150-1" }, "locus": { "chromosome": "6", "start_pos": 85137295, "end_pos": 85084583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105374.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105374.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103947.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103947.1" } ] } }, { "isoform_ac": "F1MW47-1", "url": "https://www.uniprot.org/uniprotkb/F1MW47/entry", "sequence": { "sequence": "MSKLPLQFCAQQAFSICRAVCEGAAIMMSKKWVSAILLLQLCYTGCGFCEKVLVWPCDMSHWLNLKVILEKLMERGHEVTVLVSSQNFLIENNKPSTLNFEMFSVPQDKETAEDSLNEFLNLSVNVMPTLSPWQSAKKLQDFFLQISADLKLVCESVVYNQTIMKKLQDTNYNVMVIDPVMPCGELIAETLGIPFVYTLRLSLGSTMERYCGQIPSPPSYVPVVMAALPDKMTFLQRVKNLMFTIFFDFWLQQYDSQLWDQFYSEVLGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEDGIVVFSLGSMVKNLTEEKANRIASALAQIPQKVLWRYKGKKPATLGANTRLYDWIPQNDLLGHPKAKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNINTMTSADLLNALRTVINEPSYKENAMRLKRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHNLTWYQYHSLDVIGFLLACVATAVFLVTRCCLFSCRKFGKTGKKKKRE", "length": 556, "header": "tr|F1MW47-1|G3N150_BOVIN Computationally mapped isoform of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=UGT2A1 PE=3 SV=2 CANONICAL=G3N150-1" }, "locus": { "chromosome": "6", "start_pos": 85108884, "end_pos": 85084583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053634.3", "url": "https://www.ensembl.org/id/ENSBTAT00000053634.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051040.2", "url": "https://www.ensembl.org/id/ENSBTAP00000051040.2" } ] } }, { "isoform_ac": "G3N150-1", "url": "https://www.uniprot.org/uniprotkb/G3N150/entry", "sequence": { "sequence": "MLNKIILLLSLQISLLGTTFGGNVLIWPMEGSHWLNIKTIIDELIKKGHNVTVLVASSAFCITPTTNPSLIFEIYEVPFGKERIEGVIKDFILTWMEHRPSPLTIWRFYQEMAKVIKDFHMVSREICDSVLQNEKLMEKLKKSKFEVLVSDPVFPCGDIIALKLGIPFIYSLRFSPASTVEKHCGKVPYPPSYVPAILSELTDQMSFTDRIRNFISYHLQDYMFNTLWKSWDSYYSKALGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEDGIVVFSLGSMVKNLTEEKANRIASALAQIPQKVLWRYKGKKPATLGANTRLYDWIPQNDLLGHPKAKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNINTMTSADLLNALRTVINEPSYKENAMRLKRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHNLTWYQYHSLDVIGFLLACVATAVFLVTRCCLFSCRKFGKTGKKKKRE", "length": 528, "header": "tr|G3N150-1|G3N150_BOVIN Isoform 1 of UDP-glucuronosyltransferase OS=Bos taurus OX=9913 GN=UGT2A1 PE=3 SV=2 CANONICAL=G3N150-1" }, "locus": { "chromosome": "6", "start_pos": 85137295, "end_pos": 85084583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065881.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065881.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055577.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055577.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N150", "url": "https://www.uniprot.org/uniprotkb/G3N150" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "G3N150", "url": "https://www.uniprot.org/uniprotkb/G3N150" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21032", "name": "", "equation": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9T3U6-1", "G3N150-1", "F1MFF6-1", "F1MRL5-1", "E1BBB3-1", "E1BJU8-1", "A0AAA9S6P8-1", "A0A3Q1M7T0-1", "A0A3Q1MKS1-1", "A0A3Q1LYU5-1", "A0AAA9TS57-1" ], "evidence": [ { "id": "21032", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21032" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LYU5", "gene_name": "LOC100138908", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A3Q1LYU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYU5" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A3Q1LYU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYU5" } ] } ] }, { "uniprot_ac": "A0A3Q1M7T0", "gene_name": "LOC100140261", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A3Q1M7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7T0" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A3Q1M7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7T0" } ] } ] }, { "uniprot_ac": "A0A3Q1MKS1", "gene_name": "LOC530553", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A3Q1MKS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKS1" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKS1" } ] } ] }, { "uniprot_ac": "A0AAA9S6P8", "gene_name": "LOC525484", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0AAA9S6P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6P8" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0AAA9S6P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6P8" } ] } ] }, { "uniprot_ac": "A0AAA9T3U6", "gene_name": "UGT1A1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0AAA9T3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3U6" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0AAA9T3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3U6" } ] } ] }, { "uniprot_ac": "A0AAA9TS57", "gene_name": "LOC615303", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0AAA9TS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS57" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0AAA9TS57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS57" } ] } ] }, { "uniprot_ac": "E1BBB3", "gene_name": "LOC100138004", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "E1BBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBB3" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "E1BBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBB3" } ] } ] }, { "uniprot_ac": "E1BJU8", "gene_name": "LOC100296421", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "E1BJU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "E1BJU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJU8" } ] } ] }, { "uniprot_ac": "F1MFF6", "gene_name": "UGT2B10", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "F1MFF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFF6" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "F1MFF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFF6" } ] } ] }, { "uniprot_ac": "F1MRL5", "gene_name": "LOC540544", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "F1MRL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRL5" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "F1MRL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRL5" } ] } ] }, { "uniprot_ac": "G3N150", "gene_name": "UGT2A1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "G3N150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N150" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "G3N150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N150" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N150-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 528, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N150-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N150" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.17", "ec_name": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "2.4.1.17", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.17" }, { "id": "2.4.1.17", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.17" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 314, "end_pos": 316 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RG88-1", "uniprot_ac": "F6RG88", "uniprot_id": "F6RG88_BOVIN", "mass": { "chemical_mass": 89454.0, "monoisotopic_mass": 89454.0 }, "refseq": {}, "gene_names": [ { "name": "NEK4", "type": "recommended", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase Nek4", "type": "recommended", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88/entry#names_and_taxonomy" } ] }, { "name": "Never in mitosis A-related kinase 4", "type": "synonym", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88/entry#names_and_taxonomy" } ] }, { "name": "Serine/threonine-protein kinase 2", "type": "synonym", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NEK4", "url": "https://www.uniprot.org/uniprotkb/F6RG88", "locus": { "chromosome": "22", "start_pos": 48152515, "end_pos": 48111583, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004749", "url": "https://www.ensembl.org/id/ENSBTAG00000004749" } ] } } ], "crossref": [ { "id": "F6RG88", "url": "https://alphafold.ebi.ac.uk/entry/F6RG88", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08223", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08223", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44899:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44899:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9U182", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U182", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U182-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U182-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX11", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX11-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RG88-1", "url": "https://www.uniprot.org/uniprotkb/F6RG88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLTAYCYLRVVGKGSYGEVTLVRHRRDGRQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGRLLPESQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISLFLEATKAKTSKNNVKNGDSKSKPVAAVVPGKAELSHEVVPLQSHSSESSKTYVMGEDKCLFQEKPVVIGPLKIPTSLKDHIYKPDISNTVDSLATISRVNIDILPTERRNSMNDGLVQENPPGHLDASNELEGKCNVSQVTEMLQNSKSSALPGNRIPTLSSHCVTGERNDPMKPLQPLNKDQNLPKDQDQVGGECVTGKQDRIHPALQPHSSGSEPSQSRQRRQKKREHAEHSGEKRQVSRDLIGFQETPPCLLPSLPTVGKMECTSTQKDAENQSRVVTGSVNSSRGSEIASSKDRPLSARERRRLKQSQEEIFPSGPAVRRASLGPAGPAKPQKDHLSPARRSSSDCSVAQERKLTHCLSEDELSSSTSSTDKSDGDSREGKGHTNEMTDLVQLMTQTLKLDSKESYEDLPVPDPVSEFKLHRKYRDTLILHGKVAEEAEELHFKELPSAIMPGSEKIRRIVEVLRADVIRGLGIQLLEQVYDILEEEDELEREVHLQEHMGEKYVTYSVKARQLKFFEENVNF", "length": 794, "header": "tr|F6RG88-1|F6RG88_BOVIN Isoform 1 of Serine/threonine-protein kinase Nek4 OS=Bos taurus OX=9913 GN=NEK4 PE=3 SV=2 CANONICAL=F6RG88-1" }, "isoforms": [ { "isoform_ac": "A0AAA9U182-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U182/entry", "sequence": { "sequence": "MCHQGQNQTRHMYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGRLLPESQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISLFLEATKAKTSKNNVKNGDSKSKPVAAVVPGKAELSHEVVPLQSHSSESSKTYVMGEDKCLFQEKPVVIGPLKIPTSLKDHIYKPDISNTVDSLATISRVNIDILPTERRNSMNDGLVQENPPGHLDASNELEGKCNVSQVTEMLQNSKSSALPGNRIPTLSSHCVTGERNDPMKPLQPLNKDQNLPKDQDQVGGECVTGKQDRIHPALQPHSSGSEPSQSRQRRQKKREHAEHSGEKRQFQETPPCLLPSLPTVGKMECTSTQKDAENQSRVVTGSVNSSRGSEIASSKDRPLSARERRRLKQSQEEIFPSGPAVRRASLGPAGPAKPQKDHLSPARRSSSDCSVAQERKLTHCLSEDELSSSTSSTDKSDGDSREGKGHTNEMTDLVQLMTQTLKLDSKESYEDLPVPDPVSEFKLHRKYRDTLILHGKVAEEAEELHFKELPSAIMPGSEKIRRIVEVLRADVIRGLGIQLLEQVYDILEEEDELEREVHLQEHMGEKYVTYSVKARQLKFFEENVNF", "length": 768, "header": "tr|A0AAA9U182-1|F6RG88_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase Nek4 OS=Bos taurus OX=9913 GN=NEK4 PE=3 SV=1 CANONICAL=F6RG88-1" }, "locus": { "chromosome": "22", "start_pos": 48151625, "end_pos": 48111782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102204.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102204.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103515.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103515.1" } ] } }, { "isoform_ac": "A0ABI0NX11-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX11/entry", "sequence": { "sequence": "MPLTAYCYLRVVGKGSYGEVTLVRHRRDGRQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGRLLPESQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISLFLEATKAKTSKNNVKNGDSKSKPVAAVVPGKAELSHEVVPLQSHSSESSKTYVMGEDKCLFQEKPVVIGPLKIPTSLKDHIYKPDISNTVDSLATISRVNIDILPTERRNSMNDGLVQENPPGHLDASNELEGKCNVSQVTEMLQNSKSSALPGNRIPTLSSHCVTGERNDPMKPLQPLNKDQNLPKDQDQVGGECVTGKQDRIHPALQPHSSGSEPSQSRQRRQKKREHAEHSGEKRQVSRDLIGFQETPPCLLPSLPTVGKMECTSTQKDAENQSRVVTGSVNSSRGSEIASSKDRPLSARERRRLKQSQEEIFPSGPAVRRASLGPAGPAKPQKDHLSPARRSSSDCSVAQERKLTHCLSEDELSSSTSSTDKSDGDSREGKGHTNEMTDLVQLMTQTLKLDSKESYEDLPVPDPVSEFKLHRKYRDTLILHGKVAEEAEELHFKELPSAIMPGSEKIRRIVEVLRADVIRGLGIQLLEQVYDILEEEDELEREVSIQTVAVSCLRYGIFL", "length": 781, "header": "tr|A0ABI0NX11-1|A0ABI0NX11_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase Nek4 OS=Bos taurus OX=9913 GN=NEK4 PE=3 SV=1 CANONICAL=F6RG88-1" }, "locus": { "chromosome": "22", "start_pos": 48147824, "end_pos": 48124810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148857.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148857.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105239.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105239.1" } ] } }, { "isoform_ac": "F6RG88-1", "url": "https://www.uniprot.org/uniprotkb/F6RG88/entry", "sequence": { "sequence": "MPLTAYCYLRVVGKGSYGEVTLVRHRRDGRQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGRLLPESQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISLFLEATKAKTSKNNVKNGDSKSKPVAAVVPGKAELSHEVVPLQSHSSESSKTYVMGEDKCLFQEKPVVIGPLKIPTSLKDHIYKPDISNTVDSLATISRVNIDILPTERRNSMNDGLVQENPPGHLDASNELEGKCNVSQVTEMLQNSKSSALPGNRIPTLSSHCVTGERNDPMKPLQPLNKDQNLPKDQDQVGGECVTGKQDRIHPALQPHSSGSEPSQSRQRRQKKREHAEHSGEKRQVSRDLIGFQETPPCLLPSLPTVGKMECTSTQKDAENQSRVVTGSVNSSRGSEIASSKDRPLSARERRRLKQSQEEIFPSGPAVRRASLGPAGPAKPQKDHLSPARRSSSDCSVAQERKLTHCLSEDELSSSTSSTDKSDGDSREGKGHTNEMTDLVQLMTQTLKLDSKESYEDLPVPDPVSEFKLHRKYRDTLILHGKVAEEAEELHFKELPSAIMPGSEKIRRIVEVLRADVIRGLGIQLLEQVYDILEEEDELEREVHLQEHMGEKYVTYSVKARQLKFFEENVNF", "length": 794, "header": "tr|F6RG88-1|F6RG88_BOVIN Isoform 1 of Serine/threonine-protein kinase Nek4 OS=Bos taurus OX=9913 GN=NEK4 PE=3 SV=2 CANONICAL=F6RG88-1" }, "locus": { "chromosome": "22", "start_pos": 48151625, "end_pos": 48124810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006234.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006234.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006234.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006234.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "pmid": "" }, { "name": "regulation of cellular senescence", "id": "GO:2000772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000772", "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RG88", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": 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"A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064296.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064296.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056122.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056122.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "G3N2K7", "url": "https://www.uniprot.org/uniprotkb/G3N2K7" } ], "pmid": "" }, { "name": "acetylcholine-gated monoatomic cation-selective channel activity", "id": "GO:0022848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022848", "evidence": [ { "database": "UniProtKB", "id": "G3N2K7", "url": 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"28747", "name": "", "equation": "NH4(+)(in) = NH4(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "28747", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28747" } ] }, { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MPF0-1", "A0AAA9RSQ6-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] }, { "id": "32143", "name": "", "equation": "L-arginine(in) = L-arginine(out)", "summary": "", 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"enzyme_list": [], "evidence": [ { "id": "73883", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73883" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19884", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19886", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19886", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46054", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46054", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46054:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46054:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16482", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16482", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M011", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M011", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M011-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M011-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ95", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ95-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E523-1", "url": "https://www.uniprot.org/uniprotkb/G5E523-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSAQNCESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDQLDKTGENKGWSGPKAGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSSSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQVHYCDRQSGKECVTCLTLAPVQTTFHAIGSSTEASHDQAALSALKQFSEQGLDSMEGAMNIEKGSLEKQAQHLGEKANNNQTHPGSIAQDCKKSRSVI", "length": 576, "header": "tr|G5E523-1|G5E523_BOVIN Isoform 1 of Double-stranded RNA-binding protein Staufen homolog 2 OS=Bos taurus OX=9913 GN=STAU2 PE=4 SV=3 CANONICAL=G5E523-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M011-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M011/entry", "sequence": { "sequence": "MVITWQGIGRGEPAERQTVFQSLSVPVMDTDSSMERLALAASLQDKMANPKEKTPMCLVNELARFNRVQPQYKLLKERGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSAQNCESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDQLDKTGENKGWSGPKAGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSSSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQAALSALKQFSEQGLDSMEGAMNIEKGSLEKQAQHLGEKANNNQTHPGSIAQDCKKSRSVI", "length": 616, "header": "tr|A0A3Q1M011-1|G5E523_BOVIN Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 2 OS=Bos taurus OX=9913 GN=STAU2 PE=4 SV=1 CANONICAL=G5E523-1" }, "locus": { "chromosome": "14", "start_pos": 37043311, "end_pos": 36761002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075712.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075712.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066503.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066503.2" } ] } }, { "isoform_ac": "A0A3Q1MIY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIY7/entry", "sequence": { "sequence": "MDTDSSMERLALAASLQDKMANPKEKTPMCLVNELARFNRVQPQYKLLKERGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSAQNCESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDQLDKTGENKGWSGPKAGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSSSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV", "length": 530, "header": "tr|A0A3Q1MIY7-1|G5E523_BOVIN Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 2 OS=Bos taurus OX=9913 GN=STAU2 PE=4 SV=2 CANONICAL=G5E523-1" }, "locus": { "chromosome": "14", "start_pos": 37039483, "end_pos": 36897153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085034.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085034.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070711.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070711.2" } ] } }, { "isoform_ac": "A0A3Q1MQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQN2/entry", "sequence": { "sequence": "MVARPQQSKGGQRESLGKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSAQNCESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDQLDKTGENKGWSGPKAGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSSSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQV", "length": 491, "header": "tr|A0A3Q1MQN2-1|G5E523_BOVIN Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 2 OS=Bos taurus OX=9913 GN=STAU2 PE=4 SV=1 CANONICAL=G5E523-1" }, "locus": { "chromosome": "14", "start_pos": 37063649, "end_pos": 36897153, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078121.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078121.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074340.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074340.2" } ] } }, { "isoform_ac": "A0ABI0NZ95-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ95/entry", "sequence": { "sequence": "MDTDSSMERLALAASLQDKMANPKEKTPMCLVNELARFNRVQPQYKLLKERGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSAQNCESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDQLDKTGENKGWSGPKAGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSSSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQVHYCDRQSGKECVTCLTLAPVQTTFHAIGSSTEASHDQV", "length": 568, "header": "tr|A0ABI0NZ95-1|A0ABI0NZ95_BOVIN Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 2 OS=Bos taurus OX=9913 GN=STAU2 PE=4 SV=1 CANONICAL=G5E523-1" }, "locus": { "chromosome": "14", "start_pos": 37039483, "end_pos": 36880000, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147408.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147408.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104074.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104074.1" } ] } }, { "isoform_ac": "G5E523-1", "url": "https://www.uniprot.org/uniprotkb/G5E523/entry", "sequence": { "sequence": "MLQINQMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSAQNCESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDQLDKTGENKGWSGPKAGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSSSSATIARELLMNGTSSTAEAIGLKGSSPTPPCSPVQPSKQLEYLARIQGFQVHYCDRQSGKECVTCLTLAPVQTTFHAIGSSTEASHDQAALSALKQFSEQGLDSMEGAMNIEKGSLEKQAQHLGEKANNNQTHPGSIAQDCKKSRSVI", "length": 576, "header": "tr|G5E523-1|G5E523_BOVIN Isoform 1 of Double-stranded RNA-binding protein Staufen homolog 2 OS=Bos taurus OX=9913 GN=STAU2 PE=4 SV=3 CANONICAL=G5E523-1" }, "locus": { "chromosome": "14", "start_pos": 37056113, "end_pos": 36761002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002684.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002684.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002684.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002684.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 425, "start_aa": "Thr", "end_pos": 425, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr425", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "dendrite cytoplasm", "id": "GO:0032839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032839", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "protein localization to synapse", "id": "GO:0035418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035418", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" }, { "name": "anterograde dendritic transport of messenger ribonucleoprotein complex", "id": "GO:0098964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098964", "evidence": [ { "database": "UniProtKB", "id": "G5E523", "url": "https://www.uniprot.org/uniprotkb/G5E523" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E523" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 149, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 425, 456 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 558, "end_pos": 560 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3C9-1", "uniprot_ac": "G3N3C9", "uniprot_id": "G3N3C9_BOVIN", "mass": { "chemical_mass": 76597.0, "monoisotopic_mass": 76597.0 }, "refseq": { "ac": "XP_005226590", "name": "LIM domain-binding protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226590" }, "gene_names": [ { "name": "LDB3", "type": "recommended", "evidence": [ { "id": "G3N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3C9" } ] }, { "name": "LDB3", "type": "synonym", "evidence": [ { "id": "XP_005226590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226590" } ] } ], "protein_names": [ { "name": "LIM domain binding 3", "type": "synonym", "evidence": [ { "id": "G3N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3C9/entry#names_and_taxonomy" } ] }, { "name": "LIM domain-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005226590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226590" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3C9", "url": "https://www.uniprot.org/uniprotkb/G3N3C9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LDB3", "url": "https://www.uniprot.org/uniprotkb/G3N3C9", "locus": { "chromosome": "28", "start_pos": 41383204, "end_pos": 41325440, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018707", "url": "https://www.ensembl.org/id/ENSBTAG00000018707" } ] } } ], "crossref": [ { "id": "G3N3C9", "url": "https://alphafold.ebi.ac.uk/entry/G3N3C9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018707", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018707", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06753", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06753", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09362", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09362", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09363", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09363", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09454", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09454", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536781", "url": "https://www.ncbi.nlm.nih.gov/gene/536781", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1H0", "url": "https://www.orthodb.org/?gene=A0A3Q1M1H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N3C9", "url": "https://www.orthodb.org/?gene=G3N3C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15936", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15936", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005226590", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226590", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1H0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK76", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK76-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIN5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIN5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLW5", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3C9", "url": "https://www.uniprot.org/uniprotkb/G3N3C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3C9-1", "url": "https://www.uniprot.org/uniprotkb/G3N3C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTAAPPIQSPLPVIPHQKDPALDTNSSLAAASPHPEARAGPGTPGTPELGQIFSSSFSQTPVFSSHTEASDPGPPRGGPGAKISLEGALDSLSPKAPLGSSQPRQYNNPIGLYSAETLREMAQMYQMSRRGKASGAGLLGGSLPIKDLTVDSASPVYQAVIKNQNKLEDEADDWARRSSNLQSRSFRILAQMTGTEYMQDPDEEALRRSSTPIEHAPVCTSQAATPLLPASAQSPAAASPSTASPPPATAAAHAATASATAPASSPADSPRPQASTYSPAVATSPAPAAHTYSEAPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPTPAYTPSPAPTYSPSPAPAYTPSPAPSYNPTLYSGGPAESASRPPWVTDDSFSQKFAPGKTTTTVSKQSLPRGAPAYTPPPPAPQVSPLARGTVQRAERFPASSRTPLCGHCNSIIRGPFLVAMGRSWHPEEFNCAYCKASLADVCFVEEQNNVYCERCYEQFFAPVCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYVNLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLCKKHAHAINV", "length": 723, "header": "tr|G3N3C9-1|G3N3C9_BOVIN Isoform 1 of LIM domain binding 3 OS=Bos taurus OX=9913 GN=LDB3 PE=4 SV=3 CANONICAL=G3N3C9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1H0/entry", "sequence": { "sequence": "MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTAAPPIQSPLPVIPHQKVVANSPANADYQERFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLTVDSASPVYQAVIKNQNKLEDEADDWARRSSNLQSRSFRILAQMTGTEYMQDPDEEALRRSSTPIEHAPVCTSQAATPLLPASAQSPAAASPSTASPPPATAAAHAATASATAPASSPADSPRPQASTYSPAVATSPAPAAHTYSEAPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPTPAYTPSPAPTYSPSPAPAYTPSPAPSYNPTLYSGGPAESASRPPWVTDDSFSQKFAPGKTTTTVSKQSLPRGAPAYTPPPPAPQVSPLARGTVQRAERFPASSRTPLCGHCNSIIRGPFLVAMGRSWHPEEFNCAYCKASLADVCFVEEQNNVYCERCYEQFFAPVCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYVNLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLCKKHAHAINV", "length": 676, "header": "tr|A0A3Q1M1H0-1|G3N3C9_BOVIN Computationally mapped isoform of LIM domain binding 3 OS=Bos taurus OX=9913 GN=LDB3 PE=4 SV=2 CANONICAL=G3N3C9-1" }, "locus": { "chromosome": "28", "start_pos": 41382200, "end_pos": 41325703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083205.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083205.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063798.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063798.2" } ] } }, { "isoform_ac": "A0AAA9SK76-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK76/entry", "sequence": { "sequence": "MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTAAPPIQSPLPVIPHQKDPALDTNSSLAAASPHPEARAGPGTPGTPELGQIFSSSFSQTPVFSSHTEASDPGPPRGGPGAKISLEGALDSLSPKAPLGSSQPRQYNNPIGLYSAETLREMAQMYQMSRRGKASGAGLLGGADYQERFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLTVDSASPVYQAVIKNQNKLEDEADDWARRSSNLQSRSFRILAQMTGTEYMQDPDEEALRRSRPQASTYSPAVATSPAPAAHTYSEAPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPTPAYTPSPAPTYSPSPAPAYTPSPAPSYNPTLYSGGPAESASRPPWVTDDSFSQKFAPGKTTTTVSKQSLPRGAPAYTPPPPAPQVSPLARGTVQRAERFPASSRTPLCGHCNSIIRGPFLVAMGRSWHPEEFNCAYCKASLADVCFVEEQNNVYCERCYEQFFAPVCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYVNLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLCKKHAHAINV", "length": 730, "header": "tr|A0AAA9SK76-1|G3N3C9_BOVIN Computationally mapped isoform of LIM domain binding 3 OS=Bos taurus OX=9913 GN=LDB3 PE=4 SV=1 CANONICAL=G3N3C9-1" }, "locus": { "chromosome": "28", "start_pos": 41382200, "end_pos": 41325703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110063.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110063.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086710.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086710.1" } ] } }, { "isoform_ac": "A0AAA9TIN5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIN5/entry", "sequence": { "sequence": "MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTAAPPIQSPLPVIPHQKVVANSPAKSLPIKDLTVDSASPVYQAVIKNQNKLEDEADDWARRSSNLQSRSFRILAQMTGTEYMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS", "length": 215, "header": "tr|A0AAA9TIN5-1|G3N3C9_BOVIN Computationally mapped isoform of LIM domain binding 3 OS=Bos taurus OX=9913 GN=LDB3 PE=4 SV=1 CANONICAL=G3N3C9-1" }, "locus": { "chromosome": "28", "start_pos": 41355003, "end_pos": 41325703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127949.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127949.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098324.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098324.1" } ] } }, { "isoform_ac": "A0AAF6DLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLW5/entry", "sequence": { "sequence": "MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTAAPPIQSPLPVIPHQKDPALDTNSSLAAASPHPEARAGPGTPGTPELGQIFSSSFSQTPVFSSHTEASDPGPPRGGPGAKISLEGALDSLSPKAPLGSSQPRQYNNPIGLYSAETLREMAQMYQMSRRGKASGAGLLGGADYQERFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLTVDSASPVYQAVIKNQNKLEDEADDWARRSSNLQSRSFRILAQMTGTEYMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS", "length": 398, "header": "tr|A0AAF6DLW5-1|G3N3C9_BOVIN Computationally mapped isoform of LIM domain binding 3 OS=Bos taurus OX=9913 GN=LDB3 PE=4 SV=1 CANONICAL=G3N3C9-1" }, "locus": { "chromosome": "28", "start_pos": 41355003, "end_pos": 41325703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024904.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024904.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024904.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024904.6" } ] } }, { "isoform_ac": "G3N3C9-1", "url": "https://www.uniprot.org/uniprotkb/G3N3C9/entry", "sequence": { "sequence": "MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTAAPPIQSPLPVIPHQKDPALDTNSSLAAASPHPEARAGPGTPGTPELGQIFSSSFSQTPVFSSHTEASDPGPPRGGPGAKISLEGALDSLSPKAPLGSSQPRQYNNPIGLYSAETLREMAQMYQMSRRGKASGAGLLGGSLPIKDLTVDSASPVYQAVIKNQNKLEDEADDWARRSSNLQSRSFRILAQMTGTEYMQDPDEEALRRSSTPIEHAPVCTSQAATPLLPASAQSPAAASPSTASPPPATAAAHAATASATAPASSPADSPRPQASTYSPAVATSPAPAAHTYSEAPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPTPAYTPSPAPTYSPSPAPAYTPSPAPSYNPTLYSGGPAESASRPPWVTDDSFSQKFAPGKTTTTVSKQSLPRGAPAYTPPPPAPQVSPLARGTVQRAERFPASSRTPLCGHCNSIIRGPFLVAMGRSWHPEEFNCAYCKASLADVCFVEEQNNVYCERCYEQFFAPVCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYVNLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLCKKHAHAINV", "length": 723, "header": "tr|G3N3C9-1|G3N3C9_BOVIN Isoform 1 of LIM domain binding 3 OS=Bos taurus OX=9913 GN=LDB3 PE=4 SV=3 CANONICAL=G3N3C9-1" }, "locus": { "chromosome": "28", "start_pos": 41382200, "end_pos": 41325703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065403.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065403.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056431.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056431.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], 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May be involved in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MF35", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF35#function" }, { "database": "UniProtKB", "id": "ARBA00057440", "url": "https://www.uniprot.org/uniprotkb/ARBA00057440#function" }, { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRPF40A", "url": "https://www.uniprot.org/uniprotkb/G3MXT3", "locus": { "chromosome": "2", "start_pos": 43528943, "end_pos": 43470125, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048151", "url": 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"MCSGSGRRRSSLSPTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNNMDVAAGTTSGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSAAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANASASTSASSTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPSVQDQSEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPVFSLGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDREGEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ", "length": 933, "header": "tr|G3MXT3-1|G3MXT3_BOVIN Isoform 1 of Pre-mRNA-processing factor 40 homolog A OS=Bos taurus OX=9913 GN=PRPF40A PE=3 SV=4 CANONICAL=G3MXT3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MF35-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF35/entry", "sequence": { "sequence": "MRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNNMDVAAGTTSGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSAAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANASASTSASSTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPSVQDQSEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDREGEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ", "length": 914, "header": "tr|A0A3Q1MF35-1|G3MXT3_BOVIN Computationally mapped isoform of Pre-mRNA-processing factor 40 homolog A OS=Bos taurus OX=9913 GN=PRPF40A PE=3 SV=3 CANONICAL=G3MXT3-1" }, "locus": { "chromosome": "2", "start_pos": 43527939, "end_pos": 43470369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079825.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079825.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072788.3", "url": "https://www.ensembl.org/id/ENSBTAP00000072788.3" } ] } }, { "isoform_ac": "G3MXT3-1", "url": "https://www.uniprot.org/uniprotkb/G3MXT3/entry", "sequence": { "sequence": "MCSGSGRRRSSLSPTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNNMDVAAGTTSGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSAAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANASASTSASSTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPSVQDQSEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPVFSLGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDREGEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ", "length": 933, "header": "tr|G3MXT3-1|G3MXT3_BOVIN Isoform 1 of Pre-mRNA-processing factor 40 homolog A OS=Bos taurus OX=9913 GN=PRPF40A PE=3 SV=4 CANONICAL=G3MXT3-1" }, "locus": { "chromosome": "2", "start_pos": 43527939, "end_pos": 43470324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064349.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064349.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054353.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054353.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-BTA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "pmid": "" }, { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3MXT3", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" }, { "id": "PS51676", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51676" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FF", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 419, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXT3" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 146, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 669, "end_pos": 671 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3R0-1", "uniprot_ac": "G3N3R0", "uniprot_id": "G3N3R0_BOVIN", "mass": { "chemical_mass": 108964.0, "monoisotopic_mass": 108964.0 }, "refseq": { "ac": "XP_015313829", "name": "zinc finger protein 271-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015313829" }, "gene_names": [ { "name": "LOC132342110", "type": "recommended", "evidence": [ { "id": "G3N3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" } ] }, { "name": "LOC132342110", "type": "synonym", "evidence": [ { "id": "XP_015313829", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015313829" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "G3N3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3R0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 271-like", "type": "synonym", "evidence": [ { "id": "XP_015313829", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015313829" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3R0", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132342110", "url": "https://www.uniprot.org/uniprotkb/G3N3R0", "locus": {} } ], "crossref": [ { "id": "G3N3R0", "url": "https://alphafold.ebi.ac.uk/entry/G3N3R0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030444", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030444", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000045581", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045581", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "132342110", "url": "https://www.ncbi.nlm.nih.gov/gene/132342110", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14947:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14947:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6803204", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6803204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015313829", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015313829", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML53", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML53-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3R0", "url": "https://www.uniprot.org/uniprotkb/G3N3R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3R0-1", "url": "https://www.uniprot.org/uniprotkb/G3N3R0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHSEERLTFQDVAIDFTQEEWECLDLGQRKLYRNVMLENYRNLASLGLVSKVDLVTFLELLKDPRNIRRMKTTAIYPAVSPQDTQDLMPKNPVLEDVFQKANLGIYQTFHLRNLNLMKDWEYTRVYERQRGCLYGHKEMETLTRNPKSTAKRNEQRESNWEKQQLQSSISAEKCKCLRKDFHPFMKHTCSLKENVENLEGNLVSTANTHSDSCERRLLLNIHSSMSEHLQFNNECENSQSKQFEGSMSRGSLFFPQKISSIHSKIYTVDDDGRDAIQPSLFNTYCDMVNTEQLSMYNKRSQTLSKSPSSNNYKSIYGGLRRYSGNETRYTVEGDSKLKKPQGPESSNKDSKSNKCRNTFDQMSGFSLDKSTCTGERTCSEYGKVSNHCSELTQQDTVQNAQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECSRAFNCHSLLTQHQRIHAGEKSYICKECNKAFHRSSFLIEHQRIHTGEKPYKCIVCGKAFTSNSDLIEHQRIHTLEKPYKCTECSKAFTYNSDLTEHQRIHTGEKPYKCTECSKAFTYNSLLIQHRRIHTGEKPYKCTECSKAFTYNSDRIEHQRIHTGEKPYICKECNKAFRRSSFLTQHQRIHTGEKPYKCTVCGKAFTYKSLLTKHQRIHTGEKPYKCTECSKAFTYNSSLIQHQRIHAGEKPYKCTECSKAFICNSDLIEHQRIHTGEKPYICKECNKAFRRSSFLTRHQRIHAGEQAYKCTVCGKAFTYSSNLIQHQRIHTGEKPYKCTECSKAFICYSDLTYHKRIHTGEKPYICKECNKAFHHCSVLTRHHRIHTGEKPYKCKECGKAFIRSSALTQHHRIHTGDRRYKCTECGKTFITRYNLTEHRRVHTGERPYKCTECGKAFGYKSALTLHRRMHTGERPYECTECGKAFSQSAHLSKHQRTHTGEKL", "length": 936, "header": "tr|G3N3R0-1|G3N3R0_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC132342110 PE=3 SV=4 CANONICAL=G3N3R0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1ML53-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML53/entry", "sequence": { "sequence": "MTHSEERLTFQDVAIDFTQEEWECLDLGQRKLYRNVMLENYRNLASLGLVSKVDLVTFLELLKDPRNIRRMKTTAIYPAVSPQDTQDLMPKNPVLEDVFQKANLGIYQTFHLRNLNLMKDWEYTRVYERQRGCLYGHKEMETLTRNPKSTAKRNEQRESNWEKQQLQSSISAEKCKCLRKDFHPFMKHTCSLKENVENLEGNLVSTANTHSDSCERRLLLNIHSSMSEHLQFNNECENSQSKQFEGSMSRGSLFFPQKISSIHSKIYTVDDDGRDAIQPSLFNTYCDMVNTEQLSMYNKRSQTLSKSPSSNNYKSIYGGLRRYSGNETRYTVEGDSKLKKPQGPESSNKDSKSNKCRNTFDQMSGFSLDKSTCTGERTCSEYGKVSNHCSELTQQDTVQNAQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECSRAFNCHSLLTQHQRIHAGEKSYICKECNKAFHRSSFLIEHQRIHTGEKPYKCIVCGKPLLTTQTLLNISEFILERNLINVQNVAKPLLTTHFLFNIGEFIQERNLINVQNVAKPLLIIQTVLNIREFILERNLIYVKNVTKPFVVPHFLLNISEFTLERNLINVQCVAKPLLTSHFLLNISEFILERNLINVQNVAKPLLTTQALFNISEFMLERNLINVQNVAKPLFATQTLLNISEFILERNLIYVKNVTKPFVAPHFLPDISEFTLESKLINVQYVAKPLPTAQILFNISEFILERNLINVQNVAKPLSVTQI", "length": 755, "header": "tr|A0A3Q1ML53-1|G3N3R0_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC132342110 PE=3 SV=3 CANONICAL=G3N3R0-1" }, "locus": { "chromosome": "18", "start_pos": 60428883, "end_pos": 60418586, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083153.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083153.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072368.3", "url": "https://www.ensembl.org/id/ENSBTAP00000072368.3" } ] } }, { "isoform_ac": "G3N3R0-1", "url": "https://www.uniprot.org/uniprotkb/G3N3R0/entry", "sequence": { "sequence": "MTHSEERLTFQDVAIDFTQEEWECLDLGQRKLYRNVMLENYRNLASLGLVSKVDLVTFLELLKDPRNIRRMKTTAIYPAVSPQDTQDLMPKNPVLEDVFQKANLGIYQTFHLRNLNLMKDWEYTRVYERQRGCLYGHKEMETLTRNPKSTAKRNEQRESNWEKQQLQSSISAEKCKCLRKDFHPFMKHTCSLKENVENLEGNLVSTANTHSDSCERRLLLNIHSSMSEHLQFNNECENSQSKQFEGSMSRGSLFFPQKISSIHSKIYTVDDDGRDAIQPSLFNTYCDMVNTEQLSMYNKRSQTLSKSPSSNNYKSIYGGLRRYSGNETRYTVEGDSKLKKPQGPESSNKDSKSNKCRNTFDQMSGFSLDKSTCTGERTCSEYGKVSNHCSELTQQDTVQNAQEENKCKICEKVFSKSSNLSRHRRIHTGRKPFKCTECSRAFNCHSLLTQHQRIHAGEKSYICKECNKAFHRSSFLIEHQRIHTGEKPYKCIVCGKAFTSNSDLIEHQRIHTLEKPYKCTECSKAFTYNSDLTEHQRIHTGEKPYKCTECSKAFTYNSLLIQHRRIHTGEKPYKCTECSKAFTYNSDRIEHQRIHTGEKPYICKECNKAFRRSSFLTQHQRIHTGEKPYKCTVCGKAFTYKSLLTKHQRIHTGEKPYKCTECSKAFTYNSSLIQHQRIHAGEKPYKCTECSKAFICNSDLIEHQRIHTGEKPYICKECNKAFRRSSFLTRHQRIHAGEQAYKCTVCGKAFTYSSNLIQHQRIHTGEKPYKCTECSKAFICYSDLTYHKRIHTGEKPYICKECNKAFHHCSVLTRHHRIHTGEKPYKCKECGKAFIRSSALTQHHRIHTGDRRYKCTECGKTFITRYNLTEHRRVHTGERPYKCTECGKAFGYKSALTLHRRMHTGERPYECTECGKAFSQSAHLSKHQRTHTGEKL", "length": 936, "header": "tr|G3N3R0-1|G3N3R0_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC132342110 PE=3 SV=4 CANONICAL=G3N3R0-1" }, "locus": { "chromosome": "18", "start_pos": 60428883, "end_pos": 60418128, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063821.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063821.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056569.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056569.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" }, { "id": "R-BTA-6803204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6803204", "resource": "Reactome", "description": "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N3R0", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3N3R0", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N3R0", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3N3R0", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3N3R0", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 405, "end_pos": 432, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3R0" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 78, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 326, "end_pos": 328 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 867, "end_pos": 869 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZQ6-1", "uniprot_ac": "G3MZQ6", "uniprot_id": "GIMD1_BOVIN", "mass": { "chemical_mass": 24634.0, "monoisotopic_mass": 24634.0 }, "refseq": {}, "gene_names": [ { "name": "GIMD1", "type": "recommended", "evidence": [ { "id": "G3MZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6" } ] } ], "protein_names": [ { "name": "GTPase IMAP family member GIMD1", "type": "recommended", "evidence": [ { "id": "G3MZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6/entry#names_and_taxonomy" } ] }, { "name": "GIMAP family P-loop NTPase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "G3MZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZQ6", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GIMD1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6", "locus": { "chromosome": "6", "start_pos": 18828329, "end_pos": 18816372, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047891", "url": "https://www.ensembl.org/id/ENSBTAG00000047891" } ] } } ], "crossref": [ { "id": "G3MZQ6", "url": "https://alphafold.ebi.ac.uk/entry/G3MZQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047891", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047891", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100138214", "url": "https://www.ncbi.nlm.nih.gov/gene/100138214", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100138214", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138214", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKAMTDP", "url": "https://omabrowser.org/oma/group/GKAMTDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DKN0", "url": "https://www.orthodb.org/?gene=A0A452DKN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZQ6", "url": "https://www.orthodb.org/?gene=G3MZQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04548", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A452DKN0", "url": "https://www.uniprot.org/uniprotkb/A0A452DKN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DKN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DKN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZQ6", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZQ6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSNKMTINLALFGMTQSGKSSAGNIILGSTDFHSSFAPCSVTRDCSLGRSCHFRSFMRRGGQEVTLQVQVLDTPGYPHSRLSKKHVRQEVREALAHHFGQEGLHLALLVQRADVPLCGQEESSPVQMIQELLGHTWMNYTAILFTHAEKIEEAGFNEDEYLREASETLLKLLNSIQHRYIFQYKKGNSLSEQRLKILERIIEFVKENCYQVLTFK", "length": 216, "header": "sp|G3MZQ6-1|GIMD1_BOVIN Isoform 1 of GTPase IMAP family member GIMD1 OS=Bos taurus OX=9913 GN=GIMD1 PE=3 SV=1 CANONICAL=G3MZQ6-1" }, "isoforms": [ { "isoform_ac": "A0A452DKN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DKN0/entry", "sequence": { "sequence": "MMNSNKMTINLALFGMTQSGKSSAGNIILGSTDFHSSFAPCSVTRDCSLGRSCHFRSFMRRGGQEVTLQVQVLDTPGYPHSRLSKKHVRQEVREALAHHFGQEGLHLALLVQRADVPLCGQEESSPVQMIQELLGHTWMNYTAILFTHAEKIEEAGFNEDEYLREASETLLKLLNSIQHRYIFQYKKGNSLSEQRLKILERIIEFVKENCYQVLTFK", "length": 217, "header": "tr|A0A452DKN0-1|GIMD1_BOVIN Computationally mapped isoform of GTPase IMAP family member GIMD1 OS=Bos taurus OX=9913 GN=GIMD1 PE=3 SV=1 CANONICAL=G3MZQ6-1" }, "locus": { "chromosome": "6", "start_pos": 18827325, "end_pos": 18817751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065796.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065796.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055059.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055059.2" } ] } }, { "isoform_ac": "G3MZQ6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6/entry#G3MZQ6-1", "sequence": { "sequence": "MNSNKMTINLALFGMTQSGKSSAGNIILGSTDFHSSFAPCSVTRDCSLGRSCHFRSFMRRGGQEVTLQVQVLDTPGYPHSRLSKKHVRQEVREALAHHFGQEGLHLALLVQRADVPLCGQEESSPVQMIQELLGHTWMNYTAILFTHAEKIEEAGFNEDEYLREASETLLKLLNSIQHRYIFQYKKGNSLSEQRLKILERIIEFVKENCYQVLTFK", "length": 216, "header": "sp|G3MZQ6-1|GIMD1_BOVIN Isoform 1 of GTPase IMAP family member GIMD1 OS=Bos taurus OX=9913 GN=GIMD1 PE=3 SV=1 CANONICAL=G3MZQ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "G3MZQ6", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] } ], "pathway": [ { "id": "bta:100138214", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138214", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061ILA9-1", "protein_name": "GTPase IMAP family member GIMD1", "gene_name": "Gimd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDTNKMIINLAVFGRTQSGKSSTGNILLGSTDFYSSLSPGSITKECSLGRSCHLHSFMRRGGQEITLQIQVLDTPGYPHSKLSMEHVKQEVKKALVHHFGQDGLHLALLVQRADVPFFGQEASNPVQLIQELLGDSWKNYTAVLFTHAEKIEAAGISEDEYLHEASDTLLTLLNSVQQRHAFLYDKGNWCNGQRIKILERIMEFIKENHYQVLNFT", "length": 217 }, "evidence": [ { "id": "G3MZQ6", "url": "https://omabrowser.org/oma/group/G3MZQ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XTW3-1", "protein_name": "GTPase IMAP family member GIMD1", "gene_name": "GIMD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MADSNEMTINLVVLGRTQTGKSAAGNSLLGSLDFESHLSPSSVTTCCSLGHSCRILGVTRRNGCELALRIRVLDTPSYPHSSLSKEQVKHTVRSALAHHFREEGLHLALLVLRADLPLCPDENDQTVQFIQELLGPTWKDFTAVLLTHADKAEEAGFSEEAYLHNASSTLLSLLNSVKNKYVFLDNQKSIIKEERATILRKLLNFLRQNNYQVLLKHDKE", "length": 220 }, "evidence": [ { "id": "G3MZQ6", "url": "https://omabrowser.org/oma/group/G3MZQ6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B0BMZ3-1", "protein_name": "GTPase IMAP family member GIMD1", "gene_name": "Gimd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDANKMIINLAVLGKTQSGKSSAGNVLLGSADFYSRFAPGSVTKDCSLGRSCHIHGFMRRGGHEISLQIQVLDTPGYPHSKLSTRCVKQEVKKALEHHFGQEGLHLALLVHRADMPFFGQEASDSVQLIQELLGDSWKNYTAILFTHAEKIKEAGLSEEEYLCEASDALLTLLNSVQHRHIFLYERGNSWSEQRIKILERIMEFIKENHFQVLSFT", "length": 216 }, "evidence": [ { "id": "G3MZQ6", "url": "https://omabrowser.org/oma/group/G3MZQ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PW74-1", "protein_name": "GTPase IMAP family member GIMD1", "gene_name": "Gimd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDTNKMIINLAVFGRTQSGKSSAGNVLLGSADFYSSFAPGSVTKECSLGRSCHLHGFMRRGGQEISLQIQVLDTPGYPHSKLSTRCVKQEVKKALLHHFGQEGLHLALLVQRADVPFFGQEASNAVQLMQELLGDSCKNYMAVLFTHAEELEEAGLSEEEYLREASDTLLTLLDSVQHRYIFLSGRGNLCNEQRIKILERIMEFIKENHFQVLSLA", "length": 217 }, "evidence": [ { "id": "G3MZQ6", "url": "https://omabrowser.org/oma/group/G3MZQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DJR0-1", "protein_name": "GTPase IMAP family member GIMD1", "gene_name": "GIMD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDPNKMIINLALFGMTQSGKSSAGNILLGSTDFHSSFAPCSVTTCCSLGRSCHLHSFMRRGGLEVALQVQVLDTPGYPHSRLSKKYVKQEVKEALAHHFGQGGLHLALLVQRADVPFCGQEVTDPVQMIQELLGHAWMNYTAILFTHAEKIEEAGLTEDKYLHEASDTLKTLLNSIQHKYVFQYKKGKSLNEQRMKILERIMEFIKENCYQVLTFK", "length": 217 }, "evidence": [ { "id": "G3MZQ6", "url": "https://omabrowser.org/oma/group/G3MZQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "G3MZQ6", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "G3MZQ6", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZQ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 216, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZQ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZQ6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ6" }, { "id": "PRU01057", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AIG1-type G", "eco_id": "ECO_0000255", "start_pos": 5, "end_pos": 216, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXP8-1", "uniprot_ac": "G3MXP8", "uniprot_id": "G3MXP8_BOVIN", "mass": { "chemical_mass": 53807.0, "monoisotopic_mass": 53807.0 }, "refseq": {}, "gene_names": [ { "name": "ADAMTSL5", "type": "recommended", "evidence": [ { "id": "G3MXP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXP8" } ] } ], "protein_names": [ { "name": "ADAMTS like 5", "type": "synonym", "evidence": [ { "id": "G3MXP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXP8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXP8", "url": "https://www.uniprot.org/uniprotkb/G3MXP8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADAMTSL5", "url": "https://www.uniprot.org/uniprotkb/G3MXP8", "locus": { "chromosome": "7", "start_pos": 43911191, "end_pos": 43918422, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046263", "url": "https://www.ensembl.org/id/ENSBTAG00000046263" } ] } } ], "crossref": [ { "id": "G3MXP8", "url": "https://alphafold.ebi.ac.uk/entry/G3MXP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046263", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046263", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03523", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03523", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107131164", "url": "https://www.ncbi.nlm.nih.gov/gene/107131164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WAPGRCP", "url": "https://omabrowser.org/oma/group/WAPGRCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RWZ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S667", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S667", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S667-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S667-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8G8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8G8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXP8", "url": "https://www.uniprot.org/uniprotkb/G3MXP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXP8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKLRPEKEEHLAPCHTRRPRSLWNLLLLLWTFLNCGLGGNAQGPGEWTPWGSWSRCSSSCGRGLSVRSRRCIRFPREELCWGDTHEYRLCQQPDCPPGAMPFRDLQCALYNGHPVLGTQKTYQWVPFYGAPNHCDLNCLAVGHDFYHSFGRVLDGTPCSPGAQDLCVAGRCLSAGCDGLLGSDAREDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRAAHRSRNHLALMGGDGRYVLNGNWAVSPAGTYEAAGTRVVYTRATGPEETLRAAGPTSQDLLLQVLLQEPNPGIEFEFWLPRERYGPFQAQAQVLGWSPRQPQPREVEPQPLESPTVIPPRTPIPTPEPCPPCPDTRGRAHRLLHYCGSDFVFRARVLGRVRQAQETRYEVHVQLIYKNRSPLRALEYVWAPSRCPCPPLALHRDYLLAARRLISPDGTQDRLLLPHAGYARLWSPAEDSRVRLAARHCPL", "length": 481, "header": "tr|G3MXP8-1|G3MXP8_BOVIN Isoform 1 of ADAMTS like 5 OS=Bos taurus OX=9913 GN=ADAMTSL5 PE=4 SV=2 CANONICAL=G3MXP8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWZ6/entry", "sequence": { "sequence": "MGKLRPEKEEHLAPCHTRRPRSLWNLLLLLWTFLNCGLGGNAQGPGEWTPWGSWSRCSSSCGRGLSVRSRRCIRFPREELCWGDTHEYRLCQQPDCPPGAMPFRDLQCALYNGHPVLGTQKTYQWVPFYGAPNHCDLNCLAVGHDFYHSFGRVLDGTPCSPGAQDLCVAGRCLSAGCDGLLGSDAREDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRAAHRSRNHLALMGGDGRYVLNGNWAVSPAGTYEAAGTRVVYTRATGPEETLRAAGPTSQDLLLQVLLQEPNPGIEFEFWLPRERYGPFQAQAQVLGWSPRQPQPREVEPQPLESPTVIPPRTPIPTPVFRARVLGRVRQAQETRYEVHVQLIYKNRSPLRALEYVWAPSRCPCPPLALHRDYLLAARRLISPDGTQDRLLLPHAGYARLWSPAEDSRVRLAARHCPL", "length": 457, "header": "tr|A0AAA9RWZ6-1|G3MXP8_BOVIN Computationally mapped isoform of ADAMTS like 5 OS=Bos taurus OX=9913 GN=ADAMTSL5 PE=4 SV=2 CANONICAL=G3MXP8-1" }, "locus": { "chromosome": "7", "start_pos": 43917240, "end_pos": 43912195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110266.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110266.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075671.2", "url": "https://www.ensembl.org/id/ENSBTAP00000075671.2" } ] } }, { "isoform_ac": "A0AAA9S667-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S667/entry", "sequence": { "sequence": "MGKLRPEKEEHLAPCHTRRPRSLWNLLLLLWTFLNCGLGGNAQGPGEWTPWGSWSRCSSSCGRGLSVRSRRCIRFPREELCWGDTHEYRLCQQPDCPPGAMPFRDLQCALYNGHPVLGTQKTYQWVPFYGAPNHCDLNCLAVGHDFYHSFGRVLDGTPCSPGAQDLCVAGRCLSAGCDGLLGSDAREDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRAAHRSRNHLGIAGSEGGGAPLAARIPRGGRWQGRGDGQGHFQGARADPSLAALMGGDGRYVLNGNWAVSPAGTYEAAGTRVVYTRATGPEETLRAAGPTSQDLLLQVLLQEPNPGIEFEFWLPRERYGPFQAQAQVLGWSPRQPQPREVEPQPLESPTVIPPRTPIPTPEPCPPCPDTRGRAHRLLHYCGSDFGLSMVPPTVFRARVLGRVRQAQETRYEVHVQLIYKNRSPLRALEYVWAPSRCPCPPLALHRDYLLAARRLISPDGTQDRLLLPHAGYARLWSPAEDSRVRLAARHCPL", "length": 531, "header": "tr|A0AAA9S667-1|G3MXP8_BOVIN Computationally mapped isoform of ADAMTS like 5 OS=Bos taurus OX=9913 GN=ADAMTSL5 PE=4 SV=1 CANONICAL=G3MXP8-1" }, "locus": { "chromosome": "7", "start_pos": 43917240, "end_pos": 43912195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105747.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105747.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079334.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079334.1" } ] } }, { "isoform_ac": "A0AAA9T8G8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8G8/entry", "sequence": { "sequence": "MGKLRPEKEEHLAPCHTRRPRSLWNLLLLLWTFLNCGLGGNAQGPGEWTPWGSWSRCSSSCGRGLSVRSRRCIRFPREELCWGDTHEYRLCQQPDCPPGAMPFRDLQCALYNGHPVLGTQKTYQWVPFYGAPNHCDLNCLAVGHDFYHSFGRVLDGTPCSPGAQDLCVAGRCLSAGCDGLLGSDAREDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRAAHRSRNHLGIAGSEGGGAPLAARIPRGGRWQGRGDGQGHFQGARADPSLAALMGGDGRYVLNGNWAVSPAGTYEAAGTRVVYTRATGPEETLRAAGPTSQDLLLQVLLQEPNPGIEFEFWLPRERYGPFQAQAQVLGWSPRQPQPREVEPQPLESPTVIPPRTPIPTPEPCPPCPDTRGRAHRLLHYCGSDFVFRARVLGRVRQAQETRYEVHVQLIYKNRSPLRALEYVWAPSRCPCPPLALHRDYLLAARRLISPDGTQDRLLLPHAGYARLWSPAEDSRVRLAARHCPL", "length": 523, "header": "tr|A0AAA9T8G8-1|G3MXP8_BOVIN Computationally mapped isoform of ADAMTS like 5 OS=Bos taurus OX=9913 GN=ADAMTSL5 PE=4 SV=1 CANONICAL=G3MXP8-1" }, "locus": { "chromosome": "7", "start_pos": 43917240, "end_pos": 43912195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133569.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133569.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094258.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094258.1" } ] } }, { "isoform_ac": "G3MXP8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXP8/entry", "sequence": { "sequence": "MGKLRPEKEEHLAPCHTRRPRSLWNLLLLLWTFLNCGLGGNAQGPGEWTPWGSWSRCSSSCGRGLSVRSRRCIRFPREELCWGDTHEYRLCQQPDCPPGAMPFRDLQCALYNGHPVLGTQKTYQWVPFYGAPNHCDLNCLAVGHDFYHSFGRVLDGTPCSPGAQDLCVAGRCLSAGCDGLLGSDAREDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRAAHRSRNHLALMGGDGRYVLNGNWAVSPAGTYEAAGTRVVYTRATGPEETLRAAGPTSQDLLLQVLLQEPNPGIEFEFWLPRERYGPFQAQAQVLGWSPRQPQPREVEPQPLESPTVIPPRTPIPTPEPCPPCPDTRGRAHRLLHYCGSDFVFRARVLGRVRQAQETRYEVHVQLIYKNRSPLRALEYVWAPSRCPCPPLALHRDYLLAARRLISPDGTQDRLLLPHAGYARLWSPAEDSRVRLAARHCPL", "length": 481, "header": "tr|G3MXP8-1|G3MXP8_BOVIN Isoform 1 of ADAMTS like 5 OS=Bos taurus OX=9913 GN=ADAMTSL5 PE=4 SV=2 CANONICAL=G3MXP8-1" }, "locus": { "chromosome": "7", "start_pos": 43917240, "end_pos": 43912195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065686.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065686.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054316.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054316.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 287, "start_aa": "Thr", "end_pos": 287, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr287", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RH35-1", "protein_name": "ADAMTS like 5", "gene_name": "ADAMTSL5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKLRPREAERLAPGPTGRPCPLQNLLLLWTLLNSGLGGNAQGPGEWTPWGSWSRCSSSCGRGLSVRSRRCIRFPQEELCWGDTHEYRVCQLPDCPPGAVPFRDLQCALYNGLPVLGTQKTYQWVPFYGAPNQCDLNCLAEGHDFYHSFGRVLDGTPCSPGTQGLCVAGRCLSAGCDGLLGSDAREDQCGHCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRAAHWSRNHLALMGVDGYYVLNGNWVVSPPGTYEAAGTHVVYTRAATGPEETLRATGPTSQDLLLQVLLQEPNPGIEFEFWLPRERYGPFQAQAQALGWSLRQPQPREVDLQPPEPPPAPTVIPSRTPIPTPEPCPPCPDTRGRAHRLLHYCGSDFVFRARVLGRLHQAQETRYEVRVQLIYKNRSPLQALEYVWAPSRCPCPLLALHREYLLAAQRLISPDGTQDRLLLPHAGYARPWSPAEDSRTRLVARHCPL", "length": 484 }, "evidence": [ { "id": "G3MXP8", "url": "https://omabrowser.org/oma/group/G3MXP8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GJQ1-1", "protein_name": "ADAMTS-like 5", "gene_name": "Adamtsl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNLRPGKTEWSVPGHPGSKHRRSWRDLWVQDVTLLFKRTHDWFQAPMPCCEQLELSLAQRESVHLASCRAALRAQTRGPREVWLPSKTTQSARAEMAVHSDSADHCLLGTQCSLRPRLFPPLLFLLWILLSCDLRGAAQGPGEWTLWGSWSRCSSSCGRGVSVRRRHCVRLPEEELCWGDSHEYRVCQLPDCPPGAIPFRDLQCSLYNGHPVLGTQKTYQWVPFHGAPNLCDLNCLAEGHAFYHSFGRVLDGTPCTPGTQGLCVAGRCLSAGCDGLLGSGTLEDRCGLCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRVTQRSHNHLGTSGPLGKLRLGLGGRRFLRERADRFFAALVTRDGHYVLNGDGVLSLPGTYEAAGTRVVYTRSAGPEETLQATGPTSQELLLQVLLREPNPGVHFEFWLPRERYGSFQAQVHALGWPLRQPQPREVEPQPAETTVVPEAIPARVASLAPDPCGPCPDSRGRAHRLLHYCGSDFVFQARVLGRHRLAQETRYEVRVLLIYKNRSPLRSREYVWAPGHCPCPPLAPHREYLLATRRHVSPDGTQDRLLLPQAGYARLWSPAEDSRVRLAARRCPV", "length": 609 }, "evidence": [ { "id": "G3MXP8", "url": "https://omabrowser.org/oma/group/G3MXP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZMM2-1", "protein_name": "ADAMTS-like protein 5", "gene_name": "ADAMTSL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKLRPGRVEWLASGHTERPHLFQNLLLFLWALLNCGLGVSAQGPGEWTPWVSWTRCSSSCGRGVSVRSRRCLRLPGEEPCWGDSHEYRLCQLPDCPPGAVPFRDLQCALYNGRPVLGTQKTYQWVPFHGAPNQCDLNCLAEGHAFYHSFGRVLDGTACSPGAQGVCVAGRCLSAGCDGLLGSGALEDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRVEHRSRNHLALMGGDGRYVLNGHWVVSPPGTYEAAGTHVVYTRDTGPQETLQAAGPTSHDLLLQVLLQEPNPGIEFEFWLPRERYSPFQARVQALGWPLRQPQPRGVEPQPPAAPAVTPAQTPTLAPDPCPPCPDTRGRAHRLLHYCGSDFVFQARVLGHHHQAQETRYEVRIQLVYKNRSPLRAREYVWAPGHCPCPMLAPHRDYLMAVQRLVSPDGTQDQLLLPHAGYARPWSPAEDSRIRLTARRCPG", "length": 481 }, "evidence": [ { "id": "G3MXP8", "url": "https://omabrowser.org/oma/group/G3MXP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3MXP8", "url": "https://www.uniprot.org/uniprotkb/G3MXP8" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "G3MXP8", "url": "https://www.uniprot.org/uniprotkb/G3MXP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "G3MXP8", "url": "https://www.uniprot.org/uniprotkb/G3MXP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXP8" }, { "id": "PS50189", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50189" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTR", "eco_id": "ECO_0000259", "start_pos": 360, "end_pos": 479, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 287, 356 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 409, "end_pos": 411 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X736-1", "uniprot_ac": "G3X736", "uniprot_id": "G3X736_BOVIN", "mass": { "chemical_mass": 52405.0, "monoisotopic_mass": 52405.0 }, "refseq": { "ac": "NP_001069747", "name": "COP9 signalosome complex subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069747" }, "gene_names": [ { "name": "COPS2", "type": "recommended", "evidence": [ { "id": "G3X736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X736" } ] }, { "name": "COPS2", "type": "synonym", "evidence": [ { "id": "NP_001069747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069747" } ] }, { "name": "LOC782101", "type": "synonym", "evidence": [ { "id": "G3X736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X736" } ] } ], "protein_names": [ { "name": "COP9 signalosome complex subunit 2", "type": "recommended", "evidence": [ { "id": "G3X736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X736/entry#names_and_taxonomy" } ] }, { "name": "Alien homolog", "type": "synonym", "evidence": [ { "id": "G3X736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X736/entry#names_and_taxonomy" } ] }, { "name": "COP9 constitutive photomorphogenic homolog subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001069747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069747" } ] }, { "name": "COP9 signalosome complex subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001069747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069747" } ] }, { "name": "JAB1-containing signalosome subunit 2", "type": "synonym", "evidence": [ { "id": "G3X736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X736/entry#names_and_taxonomy" } ] }, { "name": "Thyroid receptor-interacting protein 15", "type": "synonym", "evidence": [ { "id": "G3X736", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X736/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S5J5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5J5#function" }, { "database": "UniProtKB", "id": "ARBA00058166", "url": "https://www.uniprot.org/uniprotkb/ARBA00058166#function" }, { "database": "UniProtKB", "id": "G3X736", "url": "https://www.uniprot.org/uniprotkb/G3X736#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X736", "url": "https://www.uniprot.org/uniprotkb/G3X736" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "COPS2", "url": "https://www.uniprot.org/uniprotkb/G3X736", "locus": { "chromosome": "10", "start_pos": 61113961, "end_pos": 61080748, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013425", "url": "https://www.ensembl.org/id/ENSBTAG00000013425" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013425", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013425", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101907531", "url": "https://www.ncbi.nlm.nih.gov/gene/101907531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "782101", "url": "https://www.ncbi.nlm.nih.gov/gene/782101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101907531", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101907531", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "bta:782101", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782101", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEENWKD", "url": "https://omabrowser.org/oma/group/SEENWKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X736", "url": "https://www.orthodb.org/?gene=G3X736", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25983", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25983", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5696394", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696394", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6781823", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6781823", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001069747", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S5J5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5J5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X736", "url": "https://www.uniprot.org/uniprotkb/G3X736", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X736-1", "url": "https://www.uniprot.org/uniprotkb/G3X736-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 450, "header": "tr|G3X736-1|G3X736_BOVIN Isoform 1 of COP9 signalosome complex subunit 2 OS=Bos taurus OX=9913 GN=COPS2 PE=3 SV=1 CANONICAL=G3X736-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S5J5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5J5/entry", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 379, "header": "tr|A0AAA9S5J5-1|G3X736_BOVIN Computationally mapped isoform of COP9 signalosome complex subunit 2 OS=Bos taurus OX=9913 GN=COPS2 PE=3 SV=1 CANONICAL=G3X736-1" }, "locus": { "chromosome": "10", "start_pos": 61111036, "end_pos": 61080844, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097709.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097709.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080477.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080477.1" } ] } }, { "isoform_ac": "G3X736-1", "url": "https://www.uniprot.org/uniprotkb/G3X736/entry", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 450, "header": "tr|G3X736-1|G3X736_BOVIN Isoform 1 of COP9 signalosome complex subunit 2 OS=Bos taurus OX=9913 GN=COPS2 PE=3 SV=1 CANONICAL=G3X736-1" }, "locus": { "chromosome": "11", "start_pos": 84091724, "end_pos": 84090375, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122329.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122329.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100066.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100066.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101907531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101907531", "resource": "KEGG Pathway" }, { "id": "bta:782101", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782101", "resource": "KEGG Pathway" }, { "id": "R-BTA-5696394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696394", "resource": "Reactome", "description": "DNA Damage Recognition in GG-NER" }, { "id": "R-BTA-6781823", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6781823", "resource": "Reactome", "description": "Formation of TC-NER Pre-Incision Complex" }, { "id": "R-BTA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-BTA-9013422", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013422", "resource": "Reactome", "description": "RHOBTB1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "P61201-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "COPS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 443 }, "evidence": [ { "id": "G3X736", "url": "https://omabrowser.org/oma/group/G3X736/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61202-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "Cops2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 443 }, "evidence": [ { "id": "G3X736", "url": "https://omabrowser.org/oma/group/G3X736/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61203-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "Cops2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAVVSKLA", "length": 443 }, "evidence": [ { "id": "G3X736", "url": "https://omabrowser.org/oma/group/G3X736/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54HL6-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "csn2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDMMYDDDEYFDDDEDQDQNDSESEGVEIENQYYNSKGLIDESIPDAIKSYEKVVDLENGEKGEWGFKALKKITKLYFRIGDFDNMLESFKKFLPYTKSSASSNYIEKGINSVLDMVSSSNTIELDMIQKVFDLTLKSLLDTKNERVWFRTNLKLAKLLFEKAEYGRLAKILRDLHKSCELEDGTDDQKKGSQLVDIYALEIQMYTETKNNKKLKDLYKKALEIKSAIPHPRIMGIIRECGGKMHMAEKEWEKAHTDFFEAFKNYDEAGNSRRIQCLKYLVLACMLMLSTINPFDSTEAKPYKNDPDILAMTNLVMAYEKNDIYAFEKILKDNRKTIMDDPFIRMYIEDLLRNIRTQVLLKLLKPYTRIRISFISKELNIPSSDVESLLVSLILDNKIRGSIDQVNQQLELDTAKSSAYWKYTSIHKWANQIGQLNGGINNKLVS", "length": 449 }, "evidence": [ { "id": "G3X736", "url": "https://omabrowser.org/oma/group/G3X736/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6IQT4-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "cops2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEFGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTINGRIDQVNQLLELDHQKRGGARYTALDKWTNQLNSLNQAIVSKLA", "length": 443 }, "evidence": [ { "id": "G3X736", "url": "https://omabrowser.org/oma/group/G3X736/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8W207-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "CSN2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": 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371, "header": "tr|A0AAA9S778-1|F6R129_BOVIN Computationally mapped isoform of LIM domain binding 2 OS=Bos taurus OX=9913 GN=LDB2 PE=4 SV=1 CANONICAL=F6R129-1" }, "locus": { "chromosome": "6", "start_pos": 112153362, "end_pos": 111699992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113125.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113125.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081066.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081066.1" } ] } }, { "isoform_ac": "F6R129-1", "url": "https://www.uniprot.org/uniprotkb/F6R129/entry", "sequence": { "sequence": "MSSTPHDPFYSSPFGPFYRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWWDAFATEFFEDDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYVLKHSKESYHNSSITVDCDQCAMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMHAQDPQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQRMVAPPAEPTRQPTTKRRKRKNSTSSTSNSSAGNAANSTGSKKKTTAANLSLSSQVPGLGATPNRSLNPGRDGDRCQSTAVTPAGQFKQKC", "length": 331, "header": "tr|F6R129-1|F6R129_BOVIN Isoform 1 of LIM domain binding 2 OS=Bos taurus OX=9913 GN=LDB2 PE=4 SV=3 CANONICAL=F6R129-1" }, "locus": { "chromosome": "6", "start_pos": 112153362, "end_pos": 111703408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018687.6", "url": "https://www.ensembl.org/id/ENSBTAT00000018687.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018687.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018687.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 322, "start_aa": "Thr", "end_pos": 322, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr322", "evidence": [ { "id": "", "database": "GlyGen", "url": 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"snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1D5-1", "uniprot_ac": "G3N1D5", "uniprot_id": "G3N1D5_BOVIN", "mass": { "chemical_mass": 154820.0, "monoisotopic_mass": 154820.0 }, "refseq": { "ac": "XP_024851510", "name": "protein patched homolog 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851510" }, "gene_names": [ { "name": "PTCH1", "type": "recommended", "evidence": [ { "id": "G3N1D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ] }, { "name": "PTCH1", "type": "synonym", "evidence": [ { "id": "XP_024851510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851510" } ] } ], "protein_names": [ { "name": "Patched 1", "type": "synonym", "evidence": [ { "id": "G3N1D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1D5/entry#names_and_taxonomy" } ] }, { "name": "protein patched homolog 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024851510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851510" } ] } ], "function": [ { "annotation": "Negative regulator of the smoothened signaling pathway, which acts as a receptor for hedgehog (SHH, IHH and DHH) morphogens (PubMed:24990743). In absence of hedgehog, acts as an inhibitor of smoothened protein (SMO) by preventing SMO access to cholesterol: mechanistically, acts as a cholesterol transporter, which depeletes cholesterol from the outer leaflet of plasma membrane, thereby preventing cholesterol-binding to the extracellular CRD region of SMO (By similarity). Hedgehog-binding inhibits PTCH1 cholesterol transporter activity, promoting SMO activation by cholesterol and transduction of the smoothened signaling pathway (By similarity). Molecular mechanism governing cholesterol transport are still unclear: may move cholesterol from the outer to the inner leaflet of the membrane in exchange for potassium or sodium ion export in the opposite direction (By similarity). PTCH1 acts as a key specifier of bovine limb evolution, which is characterized by progressive reduction of distal skeleton to symmetrical and elongated middle digits with hoofed phalanges, due to decreased expression in limb bud mesenchyme (PubMed:24990743).", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S7E1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7E1#function" }, { "database": "PubMed", "id": "24990743", "url": "https://glygen.org/publication/PubMed/24990743" }, { "database": "UniProtKB", "id": "Q61115", "url": "https://www.uniprot.org/uniprotkb/Q61115#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PTCH1", "url": 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Classification" ] }, { "id": "bta:520994", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520994", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLYDTEW", "url": "https://omabrowser.org/oma/group/HLYDTEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0AAA9S7E1", "url": "https://www.orthodb.org/?gene=A0AAA9S7E1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N1D5", "url": "https://www.orthodb.org/?gene=G3N1D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46022", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46022", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46022:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46022:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12349", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12349", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5632681", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5632681", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5635838", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5635838", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024851510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "39747", "url": "https://www.rhea-db.org/rhea/39747", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S7E1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7E1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7E1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1D5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1D5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALRQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLQWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNATKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSRSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTETHDNTRYSPPPPYSSHGFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTMAQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTRWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKRRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICNNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLSISVVLACTFLVCAVFLLNPWTAGIIVTVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAVPAGHTNNGSDSSDSEYSSQTTVSGISEELRHYEAQQGAGGPAHQVIVEATENPVFARSTVVHPEPRHHPPSNPRQQSHLDSRTLPPGQPGQQPRRETPRECLRAPPYKPRRDAFEISTEGHSGPSNRDRTGPRGARSHNPRHHNPAFTAMGSSMPSYCQPITTVTASASVTVAVHPPPAPGPGPSRNPRSGLCPGYEDYPETDHGLFEDPHVPFNVRCERREPKVEVIELQDVECEERRHGSSSN", "length": 1388, "header": "tr|G3N1D5-1|G3N1D5_BOVIN Isoform 1 of Patched 1 OS=Bos taurus OX=9913 GN=PTCH1 PE=3 SV=3 CANONICAL=G3N1D5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S7E1-1", "url": "https://www.uniprot.org/uniprotkb/G3N1D5/entry#A0AAA9S7E1-1", "sequence": { "sequence": 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"length": 1453, "header": "sp|A0AAA9S7E1-1|G3N1D5_BOVIN Computationally mapped isoform of Patched 1 OS=Bos taurus OX=9913 GN=PTCH1 PE=3 SV=1 CANONICAL=G3N1D5-1" }, "locus": { "chromosome": "8", "start_pos": 82160454, "end_pos": 82101875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108249.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108249.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079227.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079227.1" } ] } }, { "isoform_ac": "G3N1D5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1D5/entry", "sequence": { "sequence": "MGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALRQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLQWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNATKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSRSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTETHDNTRYSPPPPYSSHGFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTMAQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTRWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKRRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICNNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLSISVVLACTFLVCAVFLLNPWTAGIIVTVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAVPAGHTNNGSDSSDSEYSSQTTVSGISEELRHYEAQQGAGGPAHQVIVEATENPVFARSTVVHPEPRHHPPSNPRQQSHLDSRTLPPGQPGQQPRRETPRECLRAPPYKPRRDAFEISTEGHSGPSNRDRTGPRGARSHNPRHHNPAFTAMGSSMPSYCQPITTVTASASVTVAVHPPPAPGPGPSRNPRSGLCPGYEDYPETDHGLFEDPHVPFNVRCERREPKVEVIELQDVECEERRHGSSSN", "length": 1388, "header": "tr|G3N1D5-1|G3N1D5_BOVIN Isoform 1 of Patched 1 OS=Bos taurus OX=9913 GN=PTCH1 PE=3 SV=3 CANONICAL=G3N1D5-1" }, "locus": { "chromosome": "8", "start_pos": 82168494, "end_pos": 82101875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064817.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064817.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055675.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055675.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1129, "start_aa": "Thr", "end_pos": 1129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1129", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 348, "start_aa": "Asn", "end_pos": 348, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn348", "evidence": [ { "id": "A0AAA9S7E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7E1#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 874, "start_aa": "Asn", "end_pos": 874, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn874", "evidence": [ { "id": "A0AAA9S7E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7E1#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S7E1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7E1" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] }, { "title": "Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.", "journal": "Nature", "date": "2014-07-03", "authors": "Lopez-Rios Javier, Duchesne Amandine, Speziale Dario, Andrey Guillaume, Peterson Kevin A, Germann Philipp, Unal Erkan, Liu Jing, Floriot Sandrine, Barbey Sarah, Gallard Yves, M\u00fcller-Gerbl Magdalena, Courtney Andrew D, Klopp Christophe, Rodriguez Sabrina, Ivanek Robert, Beisel Christian, Wicking Carol, Iber Dagmar, Robert Benoit, McMahon Andrew P, Duboule Denis, Zeller Rolf", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "reference": [ { "type": "PubMed", "id": "24990743", "url": "https://glygen.org/publication/PubMed/24990743" } ] } ], "pathway": [ { "id": "bta:520994", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520994", "resource": "KEGG Pathway" }, { "id": "R-BTA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-BTA-5632681", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5632681", "resource": "Reactome", "description": "Ligand-receptor interactions" }, { "id": "R-BTA-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" }, { "id": "R-BTA-5635838", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5635838", "resource": "Reactome", "description": "Activation of SMO" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y5A3-1", "protein_name": "Patched 1", "gene_name": "PTCH1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASAADALEPESGSSTAGGGSHPVRAARSARGRRRRSGGTRRAAAPDREYLQRPSYCDAAFALEQIAKGRATGRRAPLWLRAKFQRLLFNLGCYIQKNCGKFLVVGLLIFGAFAVGLRAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPQEDGTNVLTTEALRQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITEAGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLQWINFDPLEFLEELKKINYQVESWEEMLNKAEVGHGYMDRPCLNPADPDCPITAPNKNSTKPLDVALVLSGGCYGLSRKYMHWQEELIIGGTVKNSSGKLVSAQALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRMYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCAKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVTRVIQIEPQAYAENDNICYSSPPPYSSHSFAHETQITMQSTVQLRTEYDPHTQAYYTTAEPRSEISVQPVTVTQDSLSCQSPESASSTRDLLSQFSDSSVHCLEPPCTKWTLSTFAEKHYAPFLLKPKAKVVVIFLFLGLLGLSLYGTTRVRDGLDLTDIVPRDTREYDFIAAQFKYFSFYNMYIVTQKADYPNVQHLLYELHRSFSNVTYVLLEGDRQLPKMWLHYFRDWLQGLQDAFDSDWETGKITYSNYKNGSDDAVLAYKLLVQTGNRAKPIDISQLTKQRLVDADGIINPNAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRETSDFVEAIEKVRAICNNYTSLGIASYPNGYPFLFWEQYIGLRHWLLLSISVVLACTFLVCALFLLNPWTAGIIVVVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHIALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPACGRNRLPTPSPEPPPSIVRFALPPGHTNNGSDSSDSEYSSQTTVSGISEELHHYEATQSPGIPVHQVVVEATENPVFARSTVVQPESRHQSSPRLQSNPEAGTQQVWHQGRQPKQEVREGLRPPPYRPRRDAFEISTEGHSGPSNKDRLNHKAHSHNMRSPAFGAMGVPGSAYCQPITTVTASASVTVAVHPAVHSHNSCRGSFPSCEEYNEDDRGMFEDPHVPFNVRCERRNSKVEVIELQDVECEERTAGKISE", "length": 1443 }, "evidence": [ { "id": "G3N1D5", "url": "https://omabrowser.org/oma/group/G3N1D5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1R8E2-1", "protein_name": "Protein patched homolog 1", "gene_name": "ptch1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASAVNVSSEQENRDPDRPRVTRRNRGNYRTAAADLEYLQRPSYCDAAFALEQISEGNATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLRAANLETDVEKLWVEVGGRVNQELKYTRQKIGEEAMFSPQLMIQTPRQEGANILTVEALKQHLDSAIKASRVHVYMYNRQWTLEHLCYKSGELVTETNVVDQILEKLHPCLVITPLDCFWEGAKLHSGTFYLPGKPPLQWTNFDPMGFIAELKMLKYQVDSWEEMLVKADVGQGYMNRPCLNPADPDCPLSAPNKNTTGPFDVAPVLTGGCYGLSKKYMHWQEELIVGGTKKNDSGKLLSAQAFQTMFQLMTPKQMYEHLKGYDEVSHINWNEDKAAAILEAWQRKYSEAVQQSVPVNSSQKVLTFTTTTLEDILKSFSDVSVIRIASGYLLMLAYACLTMLRWDCAKSQGAVGLAGVLLVTLSVAAGLGLCSLLGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRFDIFCCFVSPCANRVIQLEPQAAYADSSADSSRYSPPPSYSSHSFAQHTQITMQSTVQLRTEYDPRTQAYYTTAEPHSHISVQPYAPNTNPNPNPNRNNNNNNCTNNSSSAVPGVATDTASCQSPDGASSTRDLLSQFGDSGIRCLDSPYSRWTFASFAEKHYAPFLLQSTTKVVVIFLFLALLGVSLYGTTRVRDGLELTDIVPRETGEYDFIRAQFRYFSFYNMYVVTQRADYAQIQPQLYELHQRFGSVKYILREENGQLPRMWLHYFRDWLLGLQEAFDKDWQAGRITQGNYRNGSDDGVLAYKLLVQTGRREKTITRQRLVSADGIINPNAFYIYLSAWVSNDPVAYAASQANIRPHPPEWLHDRTDSIPASRLNIPAAEPIEYAQFPFYLNGLRETPQFVEAIESVRAICNNFSRQGLPSYPNGYPFLFWEQYVGLRHWLLLSISVVLACTFLVCAVFLLNPWTAGIIVLVLSLMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDRNKRAVLALEHMFAPVLDGAFSTLLGVLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSYFGPYPEVSPADGQSRLPTPSPEPPPQVVRFTMRPSHTTPGAGSDSSDSEYGSNTTVSGISQELQQYNLQPNRGRSARLEEVRIATAGRQGSRQVELPMFPSCSDDSRQQQIQQHYRSSSHDAAPQPSKRYCSRDPKRDFGSGHPPPPHRPRMDAFETATEPGGHSGPNHRDRSGAHRPRSHNPYNPHPSHPSTGPNYCQPITTVTASASVTVAVHSGVPSQSPAYPSYPSNDSYQTSGDVHNDPHFSDPHVPFDESHDSSKVEGMELQDLEYDTANVCHTRPSS", "length": 1475 }, "evidence": [ { "id": "G3N1D5", "url": "https://omabrowser.org/oma/group/G3N1D5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P18502-1", "protein_name": "Protein patched", "gene_name": "ptc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRDSLPRVPDTHGDVVDEKLFSDLYIRTSWVDAQVALDQIDKGKARGSRTAIYLRSVFQSHLETLGSSVQKHAGKVLFVAILVLSTFCVGLKSAQIHSKVHQLWIQEGGRLEAELAYTQKTIGEDESATHQLLIQTTHDPNASVLHPQALLAHLEVLVKATAVKVHLYDTEWGLRDMCNMPSTPSFEGIYYIEQILRHLIPCSIITPLDCFWEGSQLLGPESAVVIPGLNQRLLWTTLNPASVMQYMKQKMSEEKISFDFETVEQYMKRAAIGSGYMEKPCLNPLNPNCPDTAPNKNSTQPPDVGAILSGGCYGYAAKHMHWPEELIVGGAKRNRSGHLRKAQALQSVVQLMTEKEMYDQWQDNYKVHHLGWTQEKAAEVLNAWQRNFSREVEQLLRKQSRIATNYDIYVFSSAALDDILAKFSHPSALSIVIGVAVTVLYAFCTLLRWRDPVRGQSSVGVAGVLLMCFSTAAGLGLSALLGIVFNAASTQVVPFLALGLGVDHIFMLTAAYAESNRREQTKLILKKVGPSILFSACSTAGSFFAAAFIPVPALKVFCLQAAIVMCSNLAAALLVFPAMISLDLRRRTAGRADIFCCCFPVWKEQPKVAPPVLPLNNNNGRGARHPKSCNNNRVPLPAQNPLLEQRADIPGSSHSLASFSLATFAFQHYTPFLMRSWVKFLTVMGFLAALISSLYASTRLQDGLDIIDLVPKDSNEHKFLDAQTRLFGFYSMYAVTQGNFEYPTQQQLLRDYHDSFVRVPHVIKNDNGGLPDFWLLLFSEWLGNLQKIFDEEYRDGRLTKECWFPNASSDAILAYKLIVQTGHVDNPVDKELVLTNRLVNSDGIINQRAFYNYLSAWATNDVFAYGASQGKLYPEPRQYFHQPNEYDLKIPKSLPLVYAQMPFYLHGLTDTSQIKTLIGHIRDLSVKYEGFGLPNYPSGIPFIFWEQYMTLRSSLAMILACVLLAALVLVSLLLLSVWAAVLVILSVLASLAQIFGAMTLLGIKLSAIPAVILILSVGMMLCFNVLISLGFMTSVGNRQRRVQLSMQMSLGPLVHGMLTSGVAVFMLSTSPFEFVIRHFCWLLLVVLCVGACNSLLVFPILLSMVGPEAELVPLEHPDRISTPSPLPVRSSKRSGKSYVVQGSRSSRGSCQKSHHHHHKDLNDPSLTTITEEPQSWKSSNSSIQMPNDWTYQPREQRPASYAAPPPAYHKAAAQQHHQHQGPPTTPPPPFPTAYPPELQSIVVQPEVTVETTHSDSNTTKVTATANIKVELAMPGRAVRSYNFTS", "length": 1286 }, "evidence": [ { "id": "G3N1D5", "url": "https://omabrowser.org/oma/group/G3N1D5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q13635-1", "protein_name": "Protein patched homolog 1", "gene_name": "PTCH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN", "length": 1447 }, "evidence": [ { "id": "G3N1D5", "url": "https://omabrowser.org/oma/group/G3N1D5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61115-1", "protein_name": "Protein patched homolog 1", "gene_name": "Ptch1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASAGNAAGALGRQAGGGRRRRTGGPHRAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDVALVLNGGCQGLSRKYMHWQEELIVGGTVKNATGKLVSAHALQTMFQLMTPKQMYEHFRGYDYVSHINWNEDRAAAILEAWQRTYVEVVHQSVAPNSTQKVLPFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRYSPPPPYTSHSFAHETHITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDNLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVILLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPQMWLHYFRDWLQGLQDAFDSDWETGRIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRVICNNYTSLGLSSYPNGYPFLFWEQYISLRHWLLLSISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNHRAMLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSFFGPCPEVSPANGLNRLPTPSPEPPPSVVRFAVPPGHTNNGSDSSDSEYSSQTTVSGISEELRQYEAQQGAGGPAHQVIVEATENPVFARSTVVHPDSRHQPPLTPRQQPHLDSGSLSPGRQGQQPRRDPPREGLRPPPYRPRRDAFEISTEGHSGPSNRDRSGPRGARSHNPRNPTSTAMGSSVPSYCQPITTVTASASVTVAVHPPPGPGRNPRGGPCPGYESYPETDHGVFEDPHVPFHVRCERRDSKVEVIELQDVECEERPWGSSSN", "length": 1434 }, "evidence": [ { "id": "G3N1D5", "url": "https://omabrowser.org/oma/group/G3N1D5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "hedgehog family protein binding", "id": "GO:0097108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097108", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "hedgehog receptor activity", "id": "GO:0008158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008158", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "patched binding", "id": "GO:0005113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005113", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "smoothened binding", "id": "GO:0005119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005119", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "positive regulation of cholesterol efflux", "id": "GO:0010875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010875", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "cellular response to cholesterol", "id": "GO:0071397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071397", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "pharyngeal system development", "id": "GO:0060037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060037", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "neural tube patterning", "id": "GO:0021532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021532", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "metanephric collecting duct development", "id": "GO:0072205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072205", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "limb morphogenesis", "id": "GO:0035108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035108", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "negative regulation of cell division", "id": "GO:0051782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051782", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "smooth muscle tissue development", "id": "GO:0048745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048745", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "neural plate axis specification", "id": "GO:0021997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021997", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "somite development", "id": "GO:0061053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061053", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "neural tube formation", "id": "GO:0001841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001841", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N1D5", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1150, "end_pos": 1152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "39747", "name": "", "equation": "cholesterol(in) = cholesterol(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "39747", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39747" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1D5" }, { "id": "PS50156", "database": "PROSITE", "url": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MW08-1", "uniprot_ac": "G3MW08", "uniprot_id": "G3MW08_BOVIN", "mass": { "chemical_mass": 147294.0, "monoisotopic_mass": 147294.0 }, "refseq": { "ac": "XP_024855922", "name": "ATP-binding cassette sub-family C member 4", "summary": "", "url": 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{ "name": "ATP-binding cassette sub-family C member 4", "type": "synonym", "evidence": [ { "id": "XP_024855922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855922" } ] } ], "function": [ { "annotation": "ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotic molecules. Confers resistance to anticancer agents such as methotrexate.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S7X9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7X9#function" }, { "database": "UniProtKB", "id": "ARBA00094206", "url": "https://www.uniprot.org/uniprotkb/ARBA00094206#function" }, { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08#function" }, { "database": "UniProtKB", "id": "G5E593", "url": "https://www.uniprot.org/uniprotkb/G5E593#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100337076", "url": "https://www.uniprot.org/uniprotkb/G3MW08", "locus": {} } ], "crossref": [ { "id": "G3MW08", "url": "https://alphafold.ebi.ac.uk/entry/G3MW08", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047181", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047181", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100337076", "url": "https://www.ncbi.nlm.nih.gov/gene/100337076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100337076", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024855922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "66424", "url": "https://www.rhea-db.org/rhea/66424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S7X9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7X9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7X9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MW08-1", "url": "https://www.uniprot.org/uniprotkb/G3MW08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E593", "url": "https://www.uniprot.org/uniprotkb/G5E593", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E593-1", "url": "https://www.uniprot.org/uniprotkb/G5E593-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPVSPEVKPNPLQNANFCSRLFVWWLNPLFKMGYKRKLEPNDMYSVLPEDRSQHLGEELQGHWDQEVKRAEKDAREPSLMKAIVKCYWKSYLIWGMFAFLEEGTRVVQPIFLGKIISYVENSDSTDSVTLQEAYAYATVLSACVLMWAVLHHLYFYHMQRVGMRLRVAVCHMIYRKTLRLSSSAMGKTTTGQIVNLLSNDVNKFDQVTMFLHYLWVGPLQAIIVTALLWMEIGMSCLAGMAILVVILLLQSCIWKLFSSLWSKTTALTDNRIQTISEIITGIRTIKMYAWEKSFIDLITRLRRKEIFKILRSSFFRGMHLALFFAVSKIMSFVTFMVNDILDNLITASQVFVVMMLFEALRFTSILCFPMAIEKVSEAVVSIRRIKNFLLLDEISQCYPQLPSDGEMIVDVQDFTAFWEKESGSPTLQGLSFTVRPGELLAVIGPVGTGKSSLLSAVLGELPPSQGKVSVLGRIAYVSQQPWVFSGTVRSNILFGKKYEKQRYEEVIRACALEEDLQSFEDRDLTEIGDRGTTLSGGQKARINLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCICQLLSEKITILVTHHLQYLEDATQILILKDGRMVQKGIYAEFPKPGIDFEDILLTNEDEEAEPSPGPGTPTLRNWSSSESSVQSLQSSSPSLKDATPEDKDTENIQAIPSLESSSIGMVGFKIYKNCFRAGAHWFIIVFLILINVAAQVAYFLQDWWLADWANGKSTLYAMVFGQGNMIVMPDPDWYLGTYSGLMVATGLFSIARSMLLIYVLVNSSQTLHNEMLESILKAPVLFFDRNPIGRILNRFSKDTGHMDDSLPLTFLDFIQMFILMTGVAGVMVGVIPWIAIPVIPLSIIFFLLRIYFLWTYGDIKRLECTTRSPVFSHLASSLQGLWSIRAYKAEQRFQEVFDAHQDLHSEAWFLLLTTFQWFAVRLDIICAVFFIVICFGSLMLAKTLNPGQFGLVLSLALTFTWIFQWCIRQSAEVEKMMVSAERVVEYTELEKEAPWEYEYRPPLDWPHEGELAFENVNFRHTLDGPLVLKDLTECTESKEKMGIVGRTGAGKSSLIAALFRLSEPKGGIWIDNISITSIGLHHLRKKMSVVPQEAVLFTGTMRKNLDPFDEHTNEELWNALEEVRLKETIESLPSKMDTELVESGSNLSVGQRQLLCLARGILRKNRILIIDNATSYVDPRTDELIQKNIREKFSECTVLTITHRLSTIIDSEWIMVWDSGILEDYDEPYSMLQDRDNLFYKMVQQLGEAEATVLTERAKQVHL", "length": 1294, "header": "tr|G3MW08-1|G3MW08_BOVIN Isoform 1 of Multidrug resistance-associated protein 4 OS=Bos taurus OX=9913 GN=LOC100337076 PE=3 SV=3 CANONICAL=G3MW08-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S7X9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7X9/entry", "sequence": { "sequence": "MLPVSPEVKPNPLQNANFCSRLFVWWLNPLFKMGYKRKLEPNDMYSVLPEDRSQHLGEELQGHWDQEVKRAEKDAREPSLMKAIVKCYWKSYLIWGMFAFLEEGTRVVQPIFLGKIISYVENSDSTDSVTLQEAYAYATVLSACVLMWAVLHHLYFYHMQRVGMRLRVAVCHMIYRKTLRLSSSAMGKTTTGQIVNLLSNDVNKFDQVTMFLHYLWVGPLQAIIVTALLWMEIGMSCLAGMAILVVILLLQSCIWKLFSSLWSKTTALTDNRIQTISEIITGIRTIKMYAWEKSFIDLITRLRRKEIFKILRSSFFRGMHLALFFAVSKIMSFVTFMVNDILDNLITASQVFVVMMLFEALRFTSILCFPMAIEKVSEAVVSIRRIKNFLLLDEISQCYPQLPSDGEMIVDVQDFTAFWEKDLQSFEDRDLTEIGDRGTTLSGGQKARINLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCICQLLSEKITILVTHHLQYLEDATQILILKDGRMVQKGIYAEFPKPGIDFEDILLTNEDEEAEPSPGPGTPTLRNWSSSESSVQSLQSSSPSLKDATPEDKDTENIQAIPSLESSSIGMVGFKIYKNCFRAGAHWFIIVFLILINVAAQVAYFLQDWWLADWANGKSTLYAMVFGQGNMIVMPDPDWYLGTYSGLMVATGLFSIARSMLLIYVLVNSSQTLHNEMLESILKAPVLFFDRNPIGRILNRFSKDTGHMDDSLPLTFLDFIQMFILMTGVAGVMVGVIPWIAIPVIPLSIIFFLLRIYFLWTYGDIKRLECTTRSPVFSHLASSLQGLWSIRAYKAEQRFQEVFDAHQDLHSEAWFLLLTTFQWFAVRLDIICAVFFIVICFGSLMLAKTLNPGQFGLVLSLALTFTWIFQWCIRQSAEVEKMMVSAERVVEYTELEKEAPWEYEYRPPLDWPHEGELAFENVNFRHTLDGPLVLKDLTECTESKEKMGIVGRTGAGKSSLIAALFRLSEPKGGIWIDNISITSIGLHHLRKKMSVVPQEAVLFTGTMRKNLDPFDEHTNEELWNALEEVRLKETIESLPSKMDTELVESGSNLSVGQRQLLCLARGILRKNRILIIDNATSYVDPRTDELIQKNIREKFSECTVLTITHRLSTIIDSEWIMVWDSGILEDYDEPYSMLQDRDNLFYKMVQQLGEAEATVLTERAKQVHL", "length": 1200, "header": "tr|A0AAA9S7X9-1|G3MW08_BOVIN Computationally mapped isoform of Multidrug resistance-associated protein 4 OS=Bos taurus OX=9913 GN=LOC100337076 PE=3 SV=2 CANONICAL=G3MW08-1" }, "locus": { "chromosome": "12", "start_pos": 72139274, "end_pos": 71973686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129535.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129535.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078250.2", "url": "https://www.ensembl.org/id/ENSBTAP00000078250.2" } ] } }, { "isoform_ac": "G3MW08-1", "url": "https://www.uniprot.org/uniprotkb/G3MW08/entry", "sequence": { "sequence": "MLPVSPEVKPNPLQNANFCSRLFVWWLNPLFKMGYKRKLEPNDMYSVLPEDRSQHLGEELQGHWDQEVKRAEKDAREPSLMKAIVKCYWKSYLIWGMFAFLEEGTRVVQPIFLGKIISYVENSDSTDSVTLQEAYAYATVLSACVLMWAVLHHLYFYHMQRVGMRLRVAVCHMIYRKTLRLSSSAMGKTTTGQIVNLLSNDVNKFDQVTMFLHYLWVGPLQAIIVTALLWMEIGMSCLAGMAILVVILLLQSCIWKLFSSLWSKTTALTDNRIQTISEIITGIRTIKMYAWEKSFIDLITRLRRKEIFKILRSSFFRGMHLALFFAVSKIMSFVTFMVNDILDNLITASQVFVVMMLFEALRFTSILCFPMAIEKVSEAVVSIRRIKNFLLLDEISQCYPQLPSDGEMIVDVQDFTAFWEKESGSPTLQGLSFTVRPGELLAVIGPVGTGKSSLLSAVLGELPPSQGKVSVLGRIAYVSQQPWVFSGTVRSNILFGKKYEKQRYEEVIRACALEEDLQSFEDRDLTEIGDRGTTLSGGQKARINLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCICQLLSEKITILVTHHLQYLEDATQILILKDGRMVQKGIYAEFPKPGIDFEDILLTNEDEEAEPSPGPGTPTLRNWSSSESSVQSLQSSSPSLKDATPEDKDTENIQAIPSLESSSIGMVGFKIYKNCFRAGAHWFIIVFLILINVAAQVAYFLQDWWLADWANGKSTLYAMVFGQGNMIVMPDPDWYLGTYSGLMVATGLFSIARSMLLIYVLVNSSQTLHNEMLESILKAPVLFFDRNPIGRILNRFSKDTGHMDDSLPLTFLDFIQMFILMTGVAGVMVGVIPWIAIPVIPLSIIFFLLRIYFLWTYGDIKRLECTTRSPVFSHLASSLQGLWSIRAYKAEQRFQEVFDAHQDLHSEAWFLLLTTFQWFAVRLDIICAVFFIVICFGSLMLAKTLNPGQFGLVLSLALTFTWIFQWCIRQSAEVEKMMVSAERVVEYTELEKEAPWEYEYRPPLDWPHEGELAFENVNFRHTLDGPLVLKDLTECTESKEKMGIVGRTGAGKSSLIAALFRLSEPKGGIWIDNISITSIGLHHLRKKMSVVPQEAVLFTGTMRKNLDPFDEHTNEELWNALEEVRLKETIESLPSKMDTELVESGSNLSVGQRQLLCLARGILRKNRILIIDNATSYVDPRTDELIQKNIREKFSECTVLTITHRLSTIIDSEWIMVWDSGILEDYDEPYSMLQDRDNLFYKMVQQLGEAEATVLTERAKQVHL", "length": 1294, "header": "tr|G3MW08-1|G3MW08_BOVIN Isoform 1 of Multidrug resistance-associated protein 4 OS=Bos taurus OX=9913 GN=LOC100337076 PE=3 SV=3 CANONICAL=G3MW08-1" }, "locus": { "chromosome": "12", "start_pos": 72139274, "end_pos": 71973686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035476.6", "url": "https://www.ensembl.org/id/ENSBTAT00000035476.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035351.6", "url": "https://www.ensembl.org/id/ENSBTAP00000035351.6" } ] } }, { "isoform_ac": "G5E593-1", "url": "https://www.uniprot.org/uniprotkb/G5E593/entry", "sequence": { "sequence": "MLPVSPEVKPNPLQNANFCSRLFVWWLNPLFKMGYKRKLEPNDMYSVLPEDRSQHLGEELQGHWDQEVKRAEKDAREPSLMKAIVKCYWKSYLIWGMFAFLEEGTRVVQPIFLGKIISYVENSDSTDSVTLQEAYAYATVLSACVLMWAVLHHLYFYHMQRVGMRLRVAVCHMIYRKTLRLSSSAMGKTTTGQIVNLLSNDVNKFDQVTMFLHYLWVGPLQAIIVTALLWMEIGMSCLAGMAILVVILLLQSCIWKLFSSLWSKTTALTDNRIQTISEIITGIRTIKMYAWEKSFIDLITRLRRKEIFKILRSSFFRGMHLALFFAVSKIMSFVTFMVNDILDNLITASQVFVVMMLFEALRFTSILCFPMAIEKVSEAVVSIRRIKNFLLLDEISQCYPQLPSDGEMIVDVQDFTAFWEKESGSPTLQGLSFTVRPGELLAVIGPVGTGKSSLLSAVLGELPPSQGKVSVLGRIAYVSQQPWVFSGTVRSNILFGKKYEKQRYEEVIRACALEEDLQSFEDRDLTEIGDRGTTLSGGQKARINLARAVYQDADIYLLDDPLSAVDAEVSRHLFEQCICQLLSEKITILVTHHLQYLEDATQILILKDGRMVQKGIYAEFPKPGIDFEDILLTNEDEEAEPSPGPGTPTLRNWSSSESSVQSLQSSSPSLKDATPEDKDTENIQAIPSLESSSIGMVGFKIYKNCFRAGAHWFIIVFLILINVAAQVAYFLQDWWLADWANGKSTLYAMVFGQGNMIVMPDPDWYLGTYSGRILNRFSKDTGHMDDSLPLTFLDFIQMFILMTGVAGVMVGVIPWIAIPVIPLSIIFFLLRIYFLWTYGDIKRLECTTRSPVFSHLASSLQGLWSIRAYKAEQRFQEVFDAHQDLHSEAWFLLLTTFQWFAVRLDIICAVFFIVICFGSLMLAKTLNPGQFGLVLSLALTFTWIFQWCIRQSAEVEKMMVSAERVVEYTELEKEAPWEYEYRPPLDWPHEGELAFENVNFRHTLDGPLVLKDLTECTESKEKMGIVGRTGAGKSSLIAALFRLSEPKGGIWIDNISITSIGLHHLRKKMSVVPQEAVLFTGTMRKNLDPFDEHTNEELWNALEEVRLKETIESLPSKMDTELVESGSNLSVGQRQLLCLARGILRKNRILIIDNATSYVDPRTDELIQKNIREKFSECTVLTITHRLSTIIDSEWIMVWDSGILEDYDEPYSMLQDRDNLFYKMVQQLGEAEATVLTERAKQVHL", "length": 1245, "header": "tr|G5E593-1|G5E593_BOVIN Computationally mapped isoform of Multidrug resistance-associated protein 4 OS=Bos taurus OX=9913 GN=LOC100337076 PE=3 SV=3 CANONICAL=G3MW08-1" }, "locus": { "chromosome": "12", "start_pos": 72139274, "end_pos": 71973686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010182.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010182.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010182.7", "url": "https://www.ensembl.org/id/ENSBTAP00000010182.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100337076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337076", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "ABC-type glutathione S-conjugate transporter activity", "id": "GO:0015431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015431", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "G3MW08", "url": "https://www.uniprot.org/uniprotkb/G3MW08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1103, "end_pos": 1105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1177, "end_pos": 1179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1203, "end_pos": 1205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "66424", "name": "", "equation": "leukotriene B4(in) + ATP + H2O = leukotriene B4(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9RZT1-1", "A0AAA9T569-1", "A0AAA9SJG6-1", "A0AAA9TUR1-1", "A0AAA9S3M4-1", "G3MW08-1", "A0AAA9TZ11-1", "A0A3Q1LXZ2-1", "A0AAA9T4S3-1", "A0A3Q1LPI1-1", "A0AAA9TR50-1", "A0A3Q1ML89-1", "A0AAA9SMB4-1" ], "evidence": [ { "id": "66424", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66424" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LPI1", "gene_name": "LOC107131247", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] } ] }, { "uniprot_ac": "A0A3Q1LXZ2", "gene_name": "LOC521568", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] } ] }, { "uniprot_ac": "A0A3Q1ML89", "gene_name": "LOC100299180", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] } ] }, { "uniprot_ac": "A0AAA9RZT1", "gene_name": "LOC100337390", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RZT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZT1" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an 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"A0AAA9TPG0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P098", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P098", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P098-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P098-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RGV5", "url": "https://www.uniprot.org/uniprotkb/F6RGV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RGV5-1", "url": "https://www.uniprot.org/uniprotkb/F6RGV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGAESDSDVTEGPRHALPRGRVDWALCFYVSSGAPASIRALFSEVVSPRVGCWSTPHFSCLILPSSWPDTMGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGPCLVADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYSPADTMVQYMELFNKIRKQQQILWMGRDLERTSSLSCNFSQYPT", "length": 300, "header": "tr|F6RGV5-1|F6RGV5_BOVIN Isoform 1 of Mediator of RNA polymerase II transcription subunit 20 OS=Bos taurus OX=9913 GN=MED20 PE=3 SV=2 CANONICAL=F6RGV5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TPG0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPG0/entry", "sequence": { "sequence": "MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGPCLVADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYSPADTMVQYMELFNKIRKQQQLFQPPSCWAWPVLRNSDYPGRRRLELPCFRGDGRMGVSLLSVGGKAVCVSSS", "length": 257, "header": "tr|A0AAA9TPG0-1|F6RGV5_BOVIN Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 20 OS=Bos taurus OX=9913 GN=MED20 PE=3 SV=1 CANONICAL=F6RGV5-1" }, "locus": { "chromosome": "23", "start_pos": 15687767, "end_pos": 15678450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101990.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101990.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100435.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100435.1" } ] } }, { "isoform_ac": "A0ABI0P098-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P098/entry", "sequence": { "sequence": "MGGGAESDSDVTEGPRHALPRGRVDWALCFYVSSGAPASIRALFSEVVSPRVGCWSTPHFSCLILPSSWPDTMGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGPCLVADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYSPADTMVQYMELFNKIRKQQQVIETRKPNQ", "length": 286, "header": "tr|A0ABI0P098-1|A0ABI0P098_BOVIN Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 20 OS=Bos taurus OX=9913 GN=MED20 PE=3 SV=1 CANONICAL=F6RGV5-1" }, "locus": { "chromosome": "23", "start_pos": 15687983, "end_pos": 15642768, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148683.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148683.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104659.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104659.1" } ] } }, { "isoform_ac": "F6RGV5-1", "url": "https://www.uniprot.org/uniprotkb/F6RGV5/entry", "sequence": { "sequence": "MGGGAESDSDVTEGPRHALPRGRVDWALCFYVSSGAPASIRALFSEVVSPRVGCWSTPHFSCLILPSSWPDTMGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGPCLVADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYSPADTMVQYMELFNKIRKQQQILWMGRDLERTSSLSCNFSQYPT", "length": 300, "header": "tr|F6RGV5-1|F6RGV5_BOVIN Isoform 1 of Mediator of RNA polymerase II transcription subunit 20 OS=Bos taurus OX=9913 GN=MED20 PE=3 SV=2 CANONICAL=F6RGV5-1" }, "locus": { "chromosome": "23", "start_pos": 15687983, "end_pos": 15666421, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013323.6", "url": "https://www.ensembl.org/id/ENSBTAT00000013323.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013323.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013323.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" }, { "id": "R-BTA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RGV5", "url": "https://www.uniprot.org/uniprotkb/F6RGV5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F6RGV5", "url": "https://www.uniprot.org/uniprotkb/F6RGV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "F6RGV5", "url": "https://www.uniprot.org/uniprotkb/F6RGV5" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F6RGV5", "url": "https://www.uniprot.org/uniprotkb/F6RGV5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "F6RGV5", "url": "https://www.uniprot.org/uniprotkb/F6RGV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N327-1", "uniprot_ac": "G3N327", "uniprot_id": "G3N327_BOVIN", "mass": { "chemical_mass": 22568.0, "monoisotopic_mass": 22568.0 }, "refseq": {}, "gene_names": [ { "name": "NPM2", "type": "recommended", "evidence": [ { "id": "G3N327", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ] } ], "protein_names": [ { "name": "Nucleoplasmin-2", "type": "recommended", "evidence": [ { "id": "G3N327", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N327/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SGU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGU2#function" }, { "database": "UniProtKB", "id": "ARBA00057534", "url": "https://www.uniprot.org/uniprotkb/ARBA00057534#function" }, { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NPM2", "url": "https://www.uniprot.org/uniprotkb/G3N327", "locus": { "chromosome": "8", "start_pos": 69351459, "end_pos": 69337124, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046918", "url": "https://www.ensembl.org/id/ENSBTAG00000046918" } ] } } ], "crossref": [ { "id": "G3N327", "url": "https://alphafold.ebi.ac.uk/entry/G3N327", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046918", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046918", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GQECYES", "url": "https://omabrowser.org/oma/group/GQECYES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22747", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22747", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22747:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22747:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SGU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N327-1", "url": "https://www.uniprot.org/uniprotkb/G3N327-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRSPISSTSEKETVSLLWGCELNQERPTWTFKPQKVGKQDCVLLLSTISLGEKAKEEVNVVEILPSASPDDKKRRPLTLASLRASVLPMVVLGLEFSPPVTFQLRAGSGPVFLCGQEHYNRFWEEVEEEDDDLEEEEDDDDDDEDIDMFLEETPVKQVKRLAPQKQTSAAKEKKVEKKEEAVRHHLKGSPAGKPKKPGR", "length": 200, "header": "tr|G3N327-1|G3N327_BOVIN Isoform 1 of Nucleoplasmin-2 OS=Bos taurus OX=9913 GN=NPM2 PE=3 SV=1 CANONICAL=G3N327-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGU2/entry", "sequence": { "sequence": "MNRSPISSTSEKETVSLLWGCELNQERPTWTFKPQKVGKQDCVLLLSTISLGEKAKEEVNVVEILPSASPDDKKRRPLTLASLRASVLPMVVLGLEFSPPVTFQLRAGSGPVFLCGQEHYRKKGGKKRRGSKTPS", "length": 135, "header": "tr|A0AAA9SGU2-1|G3N327_BOVIN Computationally mapped isoform of Nucleoplasmin-2 OS=Bos taurus OX=9913 GN=NPM2 PE=3 SV=1 CANONICAL=G3N327-1" }, "locus": { "chromosome": "8", "start_pos": 69351113, "end_pos": 69337146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105415.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105415.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084560.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084560.1" } ] } }, { "isoform_ac": "G3N327-1", "url": "https://www.uniprot.org/uniprotkb/G3N327/entry", "sequence": { "sequence": "MNRSPISSTSEKETVSLLWGCELNQERPTWTFKPQKVGKQDCVLLLSTISLGEKAKEEVNVVEILPSASPDDKKRRPLTLASLRASVLPMVVLGLEFSPPVTFQLRAGSGPVFLCGQEHYNRFWEEVEEEDDDLEEEEDDDDDDEDIDMFLEETPVKQVKRLAPQKQTSAAKEKKVEKKEEAVRHHLKGSPAGKPKKPGR", "length": 200, "header": "tr|G3N327-1|G3N327_BOVIN Isoform 1 of Nucleoplasmin-2 OS=Bos taurus OX=9913 GN=NPM2 PE=3 SV=1 CANONICAL=G3N327-1" }, "locus": { "chromosome": "8", "start_pos": 69351275, "end_pos": 69337146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063487.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063487.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056299.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056299.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LGI0-1", "protein_name": "Nucleoplasmin-2", "gene_name": "Npm2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSHHSTSSGTETTTKIMLWGGELSQEKQICTFRPQGEKDNCKLLLSTICLGEKAKEEVNRVEILPPANQEDRKSPVTIASLKASVLPMVTVTGVKLCPPVTFRLRAGSGPVFLSGRECYETSDASWEEEEEAEEEEDEEEEEDEEEDVDISIEESPIKQVKRMAPQKQANLAKKKRLDKEEEEEAVRPSPQDKNPWKKVKSTPKPKKSASKK", "length": 212 }, "evidence": [ { "id": "G3N327", "url": "https://omabrowser.org/oma/group/G3N327/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D0K1J0-1", "protein_name": "Nucleoplasmin-2", "gene_name": "NPM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNRSRTSSTSEKATVALLWGCELNQEKPTCTFRPQKEGKQDCKLLLSTICLGEKAREEMNLVEILPPAGQDNRKRKAITLASLRASVLPMVVLVGLELSPPVTFQLRAGSGPVFLSGQEYYDPSDLSWEEDEEEEEGPEEEEEEEDDDDDDDDDDIDVSLEKETPVKQVKRLAPQKQTSAAKVREEHHPPPWARPPELSALRPGPDLPGAQREPALAPSLTHTPHNACVWFLEEKGGKRRGSEVTVNLAKTFKLVEVLST", "length": 260 }, "evidence": [ { "id": "G3N327", "url": "https://omabrowser.org/oma/group/G3N327/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZE01-1", "protein_name": "Nucleophosmin/nucleoplasmin 2", "gene_name": "NPM2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGGGVSDKSEPPPRCSSSPSPPPSPGAMSLTESIETKSEKPMSFIWGCELSSERSSYTFQVPEEWQCEQQLALRTICLGEKARDEFHVVEVVPAEEGAVPLATLKPSVLPMATLVGVELTPPVTFRLRAGSGPVYISGQHVSLVPDLSWEEEEEEEEEAEEEEEEETPEVPPRGQVAKKGHAAKKRRLEKEAELNNASPEEPLPSKGRGGGRGRKAAARK", "length": 220 }, "evidence": [ { "id": "G3N327", "url": "https://omabrowser.org/oma/group/G3N327/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q80W85-1", "protein_name": "Nucleoplasmin-2", "gene_name": "Npm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRHSTSSVTETTAKNMLWGSELNQEKQTCTFRGQGEKKDSCKLLLSTICLGEKAKEEVNRVEVLSQEGRKPPITIATLKASVLPMVTVSGIELSPPVTFRLRTGSGPVFLSGLECYETSDLTWEDDEEEEEEEEEEDEDEDADISLEEIPVKQVKRVAPQKQMSIAKKKKVEKEEDETVVRPSPQDKSPWKKEKSTPRAKKPVTKK", "length": 207 }, "evidence": [ { "id": "G3N327", "url": "https://omabrowser.org/oma/group/G3N327/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SE8-1", "protein_name": "Nucleoplasmin-2", "gene_name": "NPM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK", "length": 214 }, "evidence": [ { "id": "G3N327", "url": "https://omabrowser.org/oma/group/G3N327/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "positive regulation of meiotic nuclear division", "id": "GO:0045836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045836", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "oocyte differentiation", "id": "GO:0009994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009994", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "positive regulation of DNA replication", "id": "GO:0045740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045740", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "blastocyst development", "id": "GO:0001824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001824", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "G3N327", "url": "https://www.uniprot.org/uniprotkb/G3N327" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N327", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N327" }, { "id": "PF03066", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03066" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoplasmin core", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 121, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1H1-1", "uniprot_ac": "G3N1H1", "uniprot_id": "G3N1H1_BOVIN", "mass": { "chemical_mass": 147280.0, "monoisotopic_mass": 147280.0 }, "refseq": {}, "gene_names": [ { "name": "IGSF1", "type": "recommended", "evidence": [ { "id": "G3N1H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ] } ], "protein_names": [ { "name": "Immunoglobulin superfamily member 1", "type": "synonym", "evidence": [ { "id": "G3N1H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1H1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IGSF1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1", "locus": { "chromosome": "X", "start_pos": 15285645, "end_pos": 15301678, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046476", "url": "https://www.ensembl.org/id/ENSBTAG00000046476" } ] } } ], "crossref": [ { "id": "G3N1H1", "url": "https://alphafold.ebi.ac.uk/entry/G3N1H1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046476", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046476", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738:SF163", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738:SF163", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738:SF186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738:SF186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SNC4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNC4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1X0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1X0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1H1-1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLDRPGEGATMLRTFTLLLFCAVMPSQPELWIESNYPQAPWENITLWCKSPSQISSKFLLLKDKTQMTWIRPSRKTFQVSFPIGALTQANTGLYRCCYWKETGWSEPSKVLELEAPGQLPKPVFWIQTETSPLPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGRVAIFSIANMTPESEGVYICRTHIQMLPTLWSEPSNPLKLIVAGLYPKPTLTAYPGPIMAPGESLNLRCQGPIYGMTFALIRLEDLEKSFYLKRPIKNEAYFFFRALKIHDAGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLAQPSPVVQMGQNVSLWCRGPVDGVGLALYKKGEDKPRQLLDTTSVYDDTSFFLNNVTSSDAGIYSCHYLLSWKTSIRTTSHNTMGLVVVDKPPKPSLSAWPSTVFKLGKAITLQCRVPHPVLEFCLEWEERATSQKFSVDGDFIISNVEGKGTGTYSCSYRIEAHPNIWSHRSEPLKLMGPAGFLTWSHILNETIRLFLIIQLVALLFVVLWIRWKCRRLRIREAWLLGTAQGVTMLFILTALLCCGLCTGVLTEETEIIMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQTHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASPPIRGKELQIRCKGWLAGMGFALYKEGMQEPIQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFETWTSPVVTPGSRVTFNCSTPQQHMSFILYKDGSEVASSDSSWASLGASAAHFLIISVGIGDGGNYSCRYYDFAIWSEPSDPVELVVTEFYPKPTLLAHPGPVVLPGKNVTLRCQGAFEGMRFALLQEGTPGPLQFRSASGNSADFLLHTVGAEDSGNYSCVYFETTMSNRGSYLSKPLMIWVTDTFPKPRLFAEPSSVVPVGQNVTLWCQGPVHGVGYILHKEIEATSVQLWGSTSNDGAFPITNVSGASIGRYSCCYHPDWTSLIKIQPSNTLELIVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELADSTFVLLKKGIQEPLKQQRPNGYRADFWMPAVSSEDSGMYSCVYYLDSAPLAASNHSDSLEIWVTDKPPKPSLSASPSTVFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDTLELVGAAGPAAQECTVGNIVRSTLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGDLGTSTDSPSSVSQGTSVEQPVPI", "length": 1327, "header": "tr|G3N1H1-1|G3N1H1_BOVIN Isoform 1 of Immunoglobulin superfamily member 1 OS=Bos taurus OX=9913 GN=IGSF1 PE=4 SV=3 CANONICAL=G3N1H1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SNC4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNC4/entry", "sequence": { "sequence": "MSEGFAASGGAHWRISNSGAGLQLPSHHLLRGKALQDSGGSMTLDRPGEGATMLRTFTLLLFCAGLSLGVTPMAVMPSQPELWIESNYPQAPWENITLWCKSPSQISSKFLLLKDKTQMTWIRPSRKTFQVSFPIGALTQANTGLYRCCYWKETGWSEPSKVLELEAPGQLPKPVFWIQTETSPLPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGRVAIFSIANMTPESEGVYICRTHIQMLPTLWSEPSNPLKLIVAGLYPKPTLTAYPGPIMAPGESLNLRCQGPIYGMTFALIRLEDLEKSFYLKRPIKNEAYFFFRALKIHDAGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLAQPSPVVQMGQNVSLWCRGPVDGVGLALYKKGEDKPRQLLDTTSVYDDTSFFLNNVTSSDAGIYSCHYLLSWKTSIRTTSHNTMGLVVVDKPPKPSLSAWPSTVFKLGKAITLQCRVPHPVLEFCLEWEERATSQKFSVDGDFIISNVEGKGTGTYSCSYRIEAHPNIWSHRSEPLKLMGPAGFLTWSHILNETIRLFLIIQLVALLFVVLWIRWKCRRLRIREAWLLGTAQGVTMLFILTALLCCGLCTGVLTEETEIIMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQTHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASPPIRGKELQIRCKGWLAGMGFALYKEGMQEPIQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFETWTSPVVTPGSRVTFNCSTPQQHMSFILYKDGSEVASSDSSWASLGASAAHFLIISVGIGDGGNYSCRYYDFAIWSEPSDPVELVVTEFYPKPTLLAHPGPVVLPGKNVTLRCQGAFEGMRFALLQEGTPGPLQFRSASGNSADFLLHTVGAEDSGNYSCVYFETTMSNRGSYLSKPLMIWVTDTFPKPRLFAEPSSVVPVGQNVTLWCQGPVHGVGYILHKEIEATSVQLWGSTSNDGAFPITNVSGASIGRYSCCYHPDWTSLIKIQPSNTLELIVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELADSTFVLLKKGIQEPLKQQRPNGYRADFWMPAVSSEDSGMYSCVYYLDSAPLAASNHSDSLEIWVTDKPPKPSLSASPSTVFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDTLELVGAAGPAAQECTVGNIVRSTLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGDLGTSTDSPSSVSQGTSVEQPVPI", "length": 1378, "header": "tr|A0AAA9SNC4-1|G3N1H1_BOVIN Computationally mapped isoform of Immunoglobulin superfamily member 1 OS=Bos taurus OX=9913 GN=IGSF1 PE=4 SV=1 CANONICAL=G3N1H1-1" }, "locus": { "chromosome": "X", "start_pos": 15301573, "end_pos": 15285935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135427.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135427.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085393.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085393.1" } ] } }, { "isoform_ac": "A0AAA9T1X0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1X0/entry", "sequence": { "sequence": "MTLDRPGEGATMLRTFTLLLFCAGLSLGVTPMVMPSQPELWIESNYPQAPWENITLWCKSPSQISSKFLLLKDKTQMTWIRPSRKTFQVSFPIGALTQANTGLYRCCYWKETGWSEPSKVLELEAPGQLPKPVFWIQTETSPLPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGRVAIFSIANMTPESEGVYICRTHIQMLPTLWSEPSNPLKLIVAGLYPKPTLTAYPGPIMAPGESLNLRCQGPIYGMTFALIRLEDLEKSFYLKRPIKNEAYFFFRALKIHDAGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLAQPSPVVQMGQNVSLWCRGPVDGVGLALYKKGEDKPRQLLDTTSVYDDTSFFLNNVTSSDAGIYSCHYLLSWKTSIRTTSHNTMGLVVVDKPPKPSLSAWPSTVFKLGKAITLQCRVPHPVLEFCLEWEERATSQKFSVDGDFIISNVEGKGTGTYSCSYRIEAHPNIWSHRSEPLKLMGPAGFLTWSHILNETIRLFLIIQLVALLFVVLWIRWKCRRLRIREAWLLGTAQGVTMLFILTALLCCGLCTGVLTEETEIIMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQTHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASPPIRGKELQIRCKGWLAGMGFALYKEGMQEPIQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFETWTSPVVTPGSRVTFNCSTPQQHMSFILYKDGSEVASSDSSWASLGASAAHFLIISVGIGDGGNYSCRYYDFAIWSEPSDPVELVVTEFYPKPTLLAHPGPVVLPGKNVTLRCQGAFEGMRFALLQEGTPGPLQFRSASGNSADFLLHTVGAEDSGNYSCVYFETTMSNRGSYLSKPLMIWVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELADSTFVLLKKGIQEPLKQQRPNGYRADFWMPAVSSEDSGMYSCVYYLDSAPLAASNHSDSLEIWVTDKPPKPSLSASPSTVFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDTLELVGAAGPAAQECTVGNIVRSTLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGDLGTSTDSPSSVSQGTSVEQPVPI", 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"MTLDRPGEGATMLRTFTLLLFCAVMPSQPELWIESNYPQAPWENITLWCKSPSQISSKFLLLKDKTQMTWIRPSRKTFQVSFPIGALTQANTGLYRCCYWKETGWSEPSKVLELEAPGQLPKPVFWIQTETSPLPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGRVAIFSIANMTPESEGVYICRTHIQMLPTLWSEPSNPLKLIVAGLYPKPTLTAYPGPIMAPGESLNLRCQGPIYGMTFALIRLEDLEKSFYLKRPIKNEAYFFFRALKIHDAGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLAQPSPVVQMGQNVSLWCRGPVDGVGLALYKKGEDKPRQLLDTTSVYDDTSFFLNNVTSSDAGIYSCHYLLSWKTSIRTTSHNTMGLVVVDKPPKPSLSAWPSTVFKLGKAITLQCRVPHPVLEFCLEWEERATSQKFSVDGDFIISNVEGKGTGTYSCSYRIEAHPNIWSHRSEPLKLMGPAGFLTWSHILNETIRLFLIIQLVALLFVVLWIRWKCRRLRIREAWLLGTAQGVTMLFILTALLCCGLCTGVLTEETEIIMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQTHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASPPIRGKELQIRCKGWLAGMGFALYKEGMQEPIQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFETWTSPVVTPGSRVTFNCSTPQQHMSFILYKDGSEVASSDSSWASLGASAAHFLIISVGIGDGGNYSCRYYDFAIWSEPSDPVELVVTEFYPKPTLLAHPGPVVLPGKNVTLRCQGAFEGMRFALLQEGTPGPLQFRSASGNSADFLLHTVGAEDSGNYSCVYFETTMSNRGSYLSKPLMIWVTDTFPKPRLFAEPSSVVPVGQNVTLWCQGPVHGVGYILHKEIEATSVQLWGSTSNDGAFPITNVSGASIGRYSCCYHPDWTSLIKIQPSNTLELIVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELADSTFVLLKKGIQEPLKQQRPNGYRADFWMPAVSSEDSGMYSCVYYLDSAPLAASNHSDSLEIWVTDKPPKPSLSASPSTVFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDTLELVGAAGPAAQECTVGNIVRSTLIVVVVVALGVVLAIEWKKWPRLRTRGSETDGRDQTIALEECNQEGDLGTSTDSPSSVSQGTSVEQPVPI", "length": 1327, "header": "tr|G3N1H1-1|G3N1H1_BOVIN Isoform 1 of Immunoglobulin superfamily member 1 OS=Bos taurus OX=9913 GN=IGSF1 PE=4 SV=3 CANONICAL=G3N1H1-1" }, "locus": { "chromosome": "X", "start_pos": 15298845, "end_pos": 15285935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064385.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064385.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055715.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055715.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 781, "start_aa": "Thr", "end_pos": 781, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr781", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "activin receptor antagonist activity", "id": "GO:0038102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038102", "evidence": [ { "database": "UniProtKB", "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ], "pmid": "" }, { "name": "inhibin binding", "id": "GO:0034711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034711", "evidence": [ { "database": "UniProtKB", "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G3N1H1", "url": "https://www.uniprot.org/uniprotkb/G3N1H1" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": 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"url": "https://www.uniprot.org/uniprotkb/G3MYV0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LAT2", "url": "https://www.uniprot.org/uniprotkb/G3MYV0", "locus": { "chromosome": "25", "start_pos": 33176555, "end_pos": 33192047, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045767", "url": "https://www.ensembl.org/id/ENSBTAG00000045767" } ] } } ], "crossref": [ { "id": "G3MYV0", "url": "https://alphafold.ebi.ac.uk/entry/G3MYV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045767", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045767", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505016", "url": "https://www.ncbi.nlm.nih.gov/gene/505016", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031428", "database": "InterPro", "categories": [ "Protein 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"https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWT2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWT2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MWT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWT2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 233, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZ54-1", "uniprot_ac": "G3MZ54", "uniprot_id": "G3MZ54_BOVIN", "mass": { "chemical_mass": 66344.0, "monoisotopic_mass": 66344.0 }, "refseq": {}, "gene_names": [ { "name": "SNX9", "type": "recommended", "evidence": [ { "id": "G3MZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ54" } ] } ], "protein_names": [ { "name": "Sorting nexin", "type": "recommended", "evidence": [ { "id": "G3MZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ54/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.", "evidence": [ { "database": "UniProtKB", "id": "F1N6W6", "url": "https://www.uniprot.org/uniprotkb/F1N6W6#function" }, { "database": "UniProtKB", "id": "ARBA00058552", "url": "https://www.uniprot.org/uniprotkb/ARBA00058552#function" }, { "database": "UniProtKB", "id": "A0A3Q1LUG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUG5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ54", "url": "https://www.uniprot.org/uniprotkb/G3MZ54" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SNX9", "url": "https://www.uniprot.org/uniprotkb/G3MZ54", "locus": { "chromosome": "9", "start_pos": 94514720, "end_pos": 94425163, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006323", "url": "https://www.ensembl.org/id/ENSBTAG00000006323" } ] } } ], "crossref": [ { "id": "G3MZ54", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ54", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006323", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006323", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07668", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07668", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11898", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11898", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506218", "url": "https://www.ncbi.nlm.nih.gov/gene/506218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506218", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506218", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MZ54", "url": "https://www.orthodb.org/?gene=G3MZ54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45827:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45827:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LUG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NG34", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NG34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6W6", "url": "https://www.uniprot.org/uniprotkb/F1N6W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6W6-1", "url": "https://www.uniprot.org/uniprotkb/F1N6W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ54", "url": "https://www.uniprot.org/uniprotkb/G3MZ54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ54-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"database": "Ensembl Peptide", "id": "ENSBTAP00000064173.3", "url": "https://www.ensembl.org/id/ENSBTAP00000064173.3" } ] } }, { "isoform_ac": "A0A3Q1NG34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG34/entry", "sequence": { "sequence": "MATKVSSGSDPWSAWNASKPANWESSDGWGAKPEGAAAQRSAANNWDSAFGHPQAYQGPATGDDDDWDEDWDEPKSSPYFKDPESAEAGGAQRGNSRASSSSMKLPLNKFPGFAKPGMEQYLLAKQLAKPKEKIPIIVGDYGPMWVYPSSTFDCVVADPRKGSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRDEKEWKTGKRKAEKDELVGVMIFSTMEPEAPDLDLVEIEQKCDAVGKFTKAMDDGVKELLNVGQEHWKRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHEYKGFLGCFPDILGAHKGAIEKVKESDKLVATSKITPQDKQNMVKRVGTMSYALQAEMNHFHSNRIYDYNSVIRLYLEQQAQFYETIAQKLRQALGRFPVM", "length": 497, "header": "tr|A0A3Q1NG34-1|G3MZ54_BOVIN Computationally mapped isoform of Sorting nexin OS=Bos taurus OX=9913 GN=SNX9 PE=3 SV=2 CANONICAL=G3MZ54-1" }, "locus": { "chromosome": "9", "start_pos": 94513110, "end_pos": 94425185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075350.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075350.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070723.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070723.2" } ] } }, { "isoform_ac": "F1N6W6-1", "url": "https://www.uniprot.org/uniprotkb/F1N6W6/entry", "sequence": { "sequence": 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"tr|G3MZI6-1|G3MZI6_BOVIN Isoform 1 of Troponin T, cardiac muscle OS=Bos taurus OX=9913 GN=TNNT2 PE=3 SV=3 CANONICAL=G3MZI6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYV4/entry", "sequence": { "sequence": "MSDVEEAVEEYEEQEEAAEEEHEEAVEEEAGGEAEAGEPCTADGEEEEGREAEDGPVEEFKPKPRPFMPNLVPPKIPDGERVDFDEKRRAERAEQQRIRAEREKERQTRLAEERARREEEESRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQNIYDLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK", "length": 243, "header": "tr|A0AAA9SYV4-1|G3MZI6_BOVIN Computationally mapped isoform of Troponin T, cardiac muscle OS=Bos taurus OX=9913 GN=TNNT2 PE=3 SV=1 CANONICAL=G3MZI6-1" }, "locus": { "chromosome": "16", "start_pos": 80942854, "end_pos": 80934811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119236.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119236.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090558.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090558.1" } ] } }, { "isoform_ac": "G3MZI6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZI6/entry", "sequence": { "sequence": "MSDVEEAVEEYEEQEEHEEAVEEEAGGEAEAGEPCTAEDGEEEEGREAEDGPVEEFKPKPRPFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQTLIEAHFENRKKEEEELVSLKDRIEKRRAERAEQQRIRAEREKERQTRLAEERARREEEESRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQNIYDLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK", "length": 278, "header": "tr|G3MZI6-1|G3MZI6_BOVIN Isoform 1 of Troponin T, cardiac muscle OS=Bos taurus OX=9913 GN=TNNT2 PE=3 SV=3 CANONICAL=G3MZI6-1" }, "locus": { "chromosome": "16", "start_pos": 80942854, "end_pos": 80934811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064811.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064811.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054984.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054984.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of muscle contraction", "id": "GO:0006937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006937", "evidence": [ { "database": "UniProtKB", "id": "G3MZI6", "url": "https://www.uniprot.org/uniprotkb/G3MZI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "troponin complex", "id": "GO:0005861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005861", "evidence": [ { "database": "UniProtKB", "id": "G3MZI6", "url": "https://www.uniprot.org/uniprotkb/G3MZI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RDI0-1", "uniprot_ac": "F6RDI0", "uniprot_id": "F6RDI0_BOVIN", "mass": { "chemical_mass": 56652.0, "monoisotopic_mass": 56652.0 }, "refseq": { "ac": "XP_005222499", "name": "E3 ubiquitin-protein ligase RAD18 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222499" }, "gene_names": [ { "name": "RAD18", "type": "recommended", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ] }, { "name": "RAD18", "type": "synonym", "evidence": [ { "id": "XP_005222499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222499" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RAD18", "type": "recommended", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RAD18 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005222499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222499" } ] }, { "name": "Postreplication repair protein RAD18", "type": "synonym", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase RAD18", "type": "synonym", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFJ1#function" }, { "database": "UniProtKB", "id": "ARBA00057007", "url": "https://www.uniprot.org/uniprotkb/ARBA00057007#function" }, { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0#function" }, { "database": "UniProtKB", "id": "A0A3Q1MHD5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHD5#function" }, { "database": "UniProtKB", "id": "A0A3Q1M8J6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8J6#function" }, { "database": "UniProtKB", "id": "G3MYC7", "url": "https://www.uniprot.org/uniprotkb/G3MYC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAD18", "url": "https://www.uniprot.org/uniprotkb/F6RDI0", "locus": { "chromosome": "22", "start_pos": 17694054, "end_pos": 17583294, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012142", "url": "https://www.ensembl.org/id/ENSBTAG00000012142" } ] } } ], "crossref": [ { "id": "F6RDI0", "url": "https://alphafold.ebi.ac.uk/entry/F6RDI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012142", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012142", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514440", "url": "https://www.ncbi.nlm.nih.gov/gene/514440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPNTGPR", "url": "https://omabrowser.org/oma/group/IPNTGPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFJ1", "url": "https://www.orthodb.org/?gene=A0A3Q1LFJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M8J6", "url": "https://www.orthodb.org/?gene=A0A3Q1M8J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MHD5", "url": "https://www.orthodb.org/?gene=A0A3Q1MHD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYC7", "url": "https://www.orthodb.org/?gene=G3MYC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14134:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14134:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-110314", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-110314", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8866654", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866654", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005222499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8J6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHD5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RDI0-1", "url": "https://www.uniprot.org/uniprotkb/F6RDI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYC7", "url": "https://www.uniprot.org/uniprotkb/G3MYC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYC7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLAEPRWPPALAVMKKVDDLLRCGICFEYFNIAMMIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRVLDELVKNLNFARNHLLQFALESPPISAASSSSKNLATKADTAVAFRHSLKQGSKLMENFLIRESGGSASELLIKENESKLSPQKKLSSPAKTRGTPSAVKSAPGSSEDSVLETPSTSALKQVTKVDCPVCGVKIPENHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKQHGLSVQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENMEKTRMRFEASKLNESVMVFTKNQTEKEIDEIHSKYRKKHQDEFHLLVDQAKKGYKKTVGMSKRKATKGDESTEKLSSVCVGQEDNKIKSSDTPSVETNHFRQSKLDFPGKLERSRQDDSFSCTDIQEEALSSSESDSFKSSSSDIIRDLLEEEEAWEASHKNDFQDREISPGQNRRTRSAESAELEPRNKRNRN", "length": 501, "header": "tr|F6RDI0-1|F6RDI0_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RAD18 OS=Bos taurus OX=9913 GN=RAD18 PE=3 SV=1 CANONICAL=F6RDI0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFJ1/entry", "sequence": { "sequence": "MDSLAEPRWPPALAVMKKVDDLLRCGICFEYFNIAMMIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRVLDELVKNLNFARNHLLQFALESPPISAASSSSKNLATKADTAVAFRHSLKQGSKLMENFLIRESGGSASELLIKENESKLSPQKKLSSPAKTRGTPSAVKSAPGSSEDSVLETPSTSALKQVTKVDCPVCGVKIPENHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKQHGLSVQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENMEKTRMRFEASKLNESVMVFTKNQTEKEIDEIHSKYRKKHQDEFHLLVDQAKKGYKKTVGMSKRKATKGDESTEKLSSVCVGQEDNKIKSSDTPSVETNHFRQSKLDFPGKLERSRQDDSFSCTDIQEEALSSSESDSFKRAGHWAAESTGDC", "length": 459, "header": "tr|A0A3Q1LFJ1-1|A0A3Q1LFJ1_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase RAD18 OS=Bos taurus OX=9913 GN=RAD18 PE=3 SV=1 CANONICAL=F6RDI0-1" }, "locus": { "chromosome": "22", "start_pos": 17656142, "end_pos": 17583359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076799.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076799.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056951.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056951.1" } ] } }, { "isoform_ac": "A0A3Q1M8J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8J6/entry", "sequence": { "sequence": "MDSLAEPRWPPALAVMKKVDDLLRCGICFEYFNIAMMIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRVLDELVKNLNFARNHLLQFALESPPISAASSSSKNLATKADTAVAFRHSLKQGSKLMENFLIRESGGSASELLIKENESKLSPQKKLSSPAKTRGTPSAVKSAPGSSEDSVLETPSTSALKQVTKVDCPVCGVKIPENHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKQHGLSVQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENMEKTRMRFEASKLNESVMVFTKNQTEKEIDEIHSKYRKKHQDEFHLLVDQAKKGYKKTVGMSKRKATKGDESTEKLSSVCVGQEDNKIKSSDTPSVETNHFRQSKLDFPGKLERSRQDDSFSCTDIQEEALSSSESDSFKSLPPEAPHPHRLPWEHF", "length": 463, "header": "tr|A0A3Q1M8J6-1|A0A3Q1M8J6_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase RAD18 OS=Bos taurus OX=9913 GN=RAD18 PE=3 SV=3 CANONICAL=F6RDI0-1" }, "locus": { "chromosome": "22", "start_pos": 17670769, "end_pos": 17583359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077254.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077254.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066440.3", "url": "https://www.ensembl.org/id/ENSBTAP00000066440.3" } ] } }, { "isoform_ac": "A0A3Q1MHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHD5/entry", "sequence": { "sequence": "MDSLAEPRWPPALAVMKKVDDLLRCGICFEYFNIAMMIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRVLDELVKNLNFARNHLLQFALESPPISAASSSSKNLATKADTAVAFRHSLKQGSKLMENFLIRESGGSASELLIKENESKLSPQKKLSSPAKTRGTPSAVKSAPGSSEDSVLETPSTSALKQVTKVDCPVCGVKIPENHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKQHGLSVQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENMEKTRMRFEASKLNESVMVFTKNQTEKEIDEIHSKYRKKHQDEFHLLVDQAKKGYKKTVGMSKRKATKGDESTEKLSSVCVGQEDNKIKSSDTPSVETNHFRQSKLDFPGKLERSRQDDSFSCTDIQEEALSSSESDSFKSSSSDIIRDLLEEEEAWEASHKENRSCCVGILTLPTSNV", "length": 485, "header": "tr|A0A3Q1MHD5-1|A0A3Q1MHD5_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase RAD18 OS=Bos taurus OX=9913 GN=RAD18 PE=3 SV=2 CANONICAL=F6RDI0-1" }, "locus": { "chromosome": "22", "start_pos": 17676977, "end_pos": 17583359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070937.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070937.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068490.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068490.2" } ] } }, { "isoform_ac": "F6RDI0-1", "url": "https://www.uniprot.org/uniprotkb/F6RDI0/entry", "sequence": { "sequence": "MDSLAEPRWPPALAVMKKVDDLLRCGICFEYFNIAMMIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRVLDELVKNLNFARNHLLQFALESPPISAASSSSKNLATKADTAVAFRHSLKQGSKLMENFLIRESGGSASELLIKENESKLSPQKKLSSPAKTRGTPSAVKSAPGSSEDSVLETPSTSALKQVTKVDCPVCGVKIPENHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKQHGLSVQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENMEKTRMRFEASKLNESVMVFTKNQTEKEIDEIHSKYRKKHQDEFHLLVDQAKKGYKKTVGMSKRKATKGDESTEKLSSVCVGQEDNKIKSSDTPSVETNHFRQSKLDFPGKLERSRQDDSFSCTDIQEEALSSSESDSFKSSSSDIIRDLLEEEEAWEASHKNDFQDREISPGQNRRTRSAESAELEPRNKRNRN", "length": 501, "header": "tr|F6RDI0-1|F6RDI0_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RAD18 OS=Bos taurus OX=9913 GN=RAD18 PE=3 SV=1 CANONICAL=F6RDI0-1" }, "locus": { "chromosome": "22", "start_pos": 17693297, "end_pos": 17583359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047319.6", "url": "https://www.ensembl.org/id/ENSBTAT00000047319.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044535.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044535.4" } ] } }, { "isoform_ac": "G3MYC7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYC7/entry", "sequence": { "sequence": "MDSLAEPRWPPALAVMKKVDDLLRCGICFEYFNIAMMIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRVLDELVKNLNFARNHLLQFALESPPISAASSSSKNLATKADTAVAFRHSLKQGSKLMENFLIRESGGSASELLIKENESKLSPQKKLSSPAKTRGTPSAVKSAPGSSEDSVLETPSTSALKQVTKVDCPVCGVKIPENHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKQHGLSVQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENMEKTRMRFEASKLNESVMVFTKNQTEKEIDEIHSKYRKKHQDEFHLLVDQAKKGYKKTVGMSKRKATKGDESTEKLSSVCVGQEDNKIKSSDTPSVETNHFRQSKLDFPGKLERSRQDDSFSCTDIQEEALSSSESDSFKRNDFQDREISPGQNRRTRSAESAELEPRNKRNRN", "length": 480, "header": "tr|G3MYC7-1|F6RDI0_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase RAD18 OS=Bos taurus OX=9913 GN=RAD18 PE=3 SV=1 CANONICAL=F6RDI0-1" }, "locus": { "chromosome": "22", "start_pos": 17693297, "end_pos": 17583359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066111.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066111.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054559.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054559.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-110314", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-110314", "resource": "Reactome", "description": "Recognition of DNA damage by PCNA-containing replication complex" }, { "id": "R-BTA-8866654", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866654", "resource": "Reactome", "description": "E3 ubiquitin ligases ubiquitinate target proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z470-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "RAD18", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLVLVLGCAVLASRGGSVARAALCSQFQPSETCCPANGNAAELCEEDNCSLCIRKFLSYKTQCPTCCVAVSESDLKNNRTLDELVKSFSSARQQLVQLVLDTPLISSPLACSRRSIGKNHSKTPASLPVVKEEVPVIDSFLKKENVCTLTKTDGLAGTDWKVCKTEEHHSSSSSSPEAGSKDNKAGSRECSEGTNSGEKPSTSVVKVVNKVDCPVCGVAIPEEYINKHLDSCLSREEKKDCLRSSAHKRKPMPKVVYNLLSDRDLKKKLKEHGLSSHGSRQQLIKRHQEFVHVYNAQCDSLNPKSVAEIVKELAKNEKIRVQLELNKSGENSLTFTKDQTEEEIDEIHTSYRNKHRSEFQFLVDQVKNRWEKSGKRETESTQKKKEGTAIGLPAGTGEGPEEHRSAAVLGEAQVLKPGTPDGKRSDPCSSEEGQGSVSLAFSDSSGSSSSSSSDILRDLEAEICSVSSDSNCLLDLKASKRKVCQSELPGGDRLLPRSKRKKS", "length": 503 }, "evidence": [ { "id": "F6RDI0", "url": "https://omabrowser.org/oma/group/F6RDI0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P10862-1", "protein_name": "Postreplication repair E3 ubiquitin-protein ligase RAD18", "gene_name": "RAD18", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDHQITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLTPCGHTFCSLCIRTHLNNQPNCPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNHYEMLWNSNFCDSLEPVDEAELKRQLLSWDVSHNKTPQNSSNKGGISKLMIMKSNGKSSSYRKLLENFKNDKFNRKGWMVMFRKDFARLIREAKMKIKTGSSDSSGSVGHSNDGDGVEKVQSDQGTEDQQMEKDQDTVINEDRVAGERNLPNEDSTDADLSRELMDLNEYSKDPPGNN", "length": 487 }, "evidence": [ { "id": "F6RDI0", "url": "https://omabrowser.org/oma/group/F6RDI0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9NS91-1", "protein_name": "E3 ubiquitin-protein ligase RAD18", "gene_name": "RAD18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPVASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPDPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVREIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREEDSSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRAAESAEIEPRNKRNRN", "length": 495 }, "evidence": [ { "id": "F6RDI0", "url": "https://omabrowser.org/oma/group/F6RDI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXK2-1", "protein_name": "E3 ubiquitin-protein ligase RAD18", "gene_name": "Rad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLAEPRWPPGLAVMKTIDDLLRCGICFEYFNIAVIIPQCSHNYCSLCIRKFLSYKTQCPTCCVAVTEPDLRNNRLLDELVKSMNFARTHLLQFALESPPISPVSSTSKKVVVKVHNADAAQHPVKQANRLMDKFLIRETGDCVFELLGKENERKFSPQKELSTSAEIKETSLLGKPVLGLSDANGPVTPSTSTMKLDTKVSCPVCGVSIPENHINKHLDSCLSREEKKESLRSSAHKRKPLPKTVYNLLSDRDLKKKLKQYGLSVQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIESMEKTRMRLEASKLNENVMVFTKNQTEKEIEEVHSEYRKKHQNAFQLLVDQAKKGYKKTGRVSQAAAMRTDEPAETLPSMRTDEPAETLPSMRTDEPAETLPLMRADEPAETLPSECIAQEDNVSFSDTVSVTNHFPQPQLDSPGPSEPERPDDSSSCTDILFSSDSDSCNRNDQNREVSPQQTRRTRASECVEIEPRNKRNKN", "length": 509 }, "evidence": [ { "id": "F6RDI0", "url": "https://omabrowser.org/oma/group/F6RDI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "nuclear inclusion body", "id": "GO:0042405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042405", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "Rad6-Rad18 complex", "id": "GO:0097505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097505", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "DNA damage tolerance", "id": "GO:0006301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006301", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "positive regulation of chromosome segregation", "id": "GO:0051984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051984", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" }, { "name": "Y-form DNA binding", "id": "GO:0000403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000403", "evidence": [ { "database": "UniProtKB", "id": "F6RDI0", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-5652005", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BNZ6-1", "Q32P99-1", "A0AAA9SFP0-1", "F6RDI0-1" ], "evidence": [ { "id": "R-BTA-5652005", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5652005" } ] }, { "id": "R-BTA-5652009", "name": "RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BNZ6-1", "Q32P99-1", "A0AAA9SFP0-1", "F6RDI0-1" ], "evidence": [ { "id": "R-BTA-5652009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5652009" } ] }, { "id": "R-BTA-8943003", "name": "SHPRH polyubiquitinates monoubiquitinated PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q32P99-1", "F6RDI0-1", "E1BLB1-1" ], "evidence": [ { "id": "R-BTA-8943003", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943003" } ] }, { "id": "R-BTA-8943007", "name": "SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q32P99-1", "F6RDI0-1", "E1BLB1-1" ], "evidence": [ { "id": "R-BTA-8943007", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943007" } ] }, { "id": "R-BTA-8943040", "name": "HLTF polyubiquitinates monoubiquitinated PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q32P99-1", "A0AAA9RXM7-1", "F6RDI0-1" ], "evidence": [ { "id": "R-BTA-8943040", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943040" } ] }, { "id": "R-BTA-8943041", "name": "HLTF binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P5K3-1", "Q32P99-1", "A0AAA9RXM7-1", "F6RDI0-1" ], "evidence": [ { "id": "R-BTA-8943041", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943041" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] } ] }, { "uniprot_ac": "A0AAA9SFP0", "gene_name": "POLE", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0AAA9SFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFP0" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0AAA9SFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFP0" } ] } ] }, { "uniprot_ac": "E1BLB1", "gene_name": "SHPRH", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BLB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BLB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLB1" } ] } ] }, { "uniprot_ac": "E1BNZ6", "gene_name": "POLD1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BNZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNZ6" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "E1BNZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNZ6" } ] } ] }, { "uniprot_ac": "F6RDI0", "gene_name": "RAD18", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 63, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RDI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RDI0" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"A0ABI0NVJ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWJ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ36-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1D3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1D3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P348", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P348", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P348-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P348-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4D1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4D1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3S2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3S2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARKLSALEILLIIFIIIVLAVDILFLMLLLEKPSGASFVPECPEIPESERIDCAPGQEVTEDVCRQRYKCCWKPVPDTAIPWCFFPRNWGYEISNLVKNTSTEYEAQLRRLPSPSLFGYDVIDTLFRAEYQTSNRFHFKITDFNNMRYEVPHENVKLFDGNADASNLSYHLEVIHKPFSIKIMRASNKRVLLDTSIGPLQFAQQYLQLSMRLPSANVYGLGEHVHQQYRHNMTWKTWPIFTRDATPTEGMINLYGAHTFFLCLEDTSGFSFGVFLMNSNAMEVTLQPAPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPFLPPYWSLGFQLSRRNYGGIDGLKNVVNRTREAEIPYDVQYSDIDYMDEKKDFTIDGVAFRGLSGFAEELHKNGLKYVIIMNPGILNNSDYQPYANGSRKRVWILGDKGFVVGQAYPGWTVFPDFTNPDCTEWWKEQFSEFYKTLEFDGVWIEMDEVSSFLQSSDQDCEVNNFNFPPFKPRVLDHLLFARTLCMDTEFHGGFHYDVHSLYGYTMAKATDSAMENIFRNKRRFILSRSTFAGSGKFAAHWLGDNAARWDDLRWSIPGILEFNLFGIPMVGANICGYRENVTEELCRRWMQLGAFYPLSRNHNGPGFRDQDPAAFSENNAMLLESSRYYLNIRYTLLPYLYTLFYRAHTLGETVARPLVHEFYQDPATWEVHEQFLWGPGLLITPVLYEGLNYARAYIPDAIWYDYETQVAIEWRKQFVEMLLPGDRIGLHLRGGYIFPIQQPNTTTETSRKNSLGLIIALDSKREAKGELYWDDGVSKDAVTGNNYILYKFSITSNRLQATIIHANYTDPDKLTFTDIMILGMDKEPTNFTVSLNDVTTSISNVVYTESTKVVNITDLEGLVLGQAFSIQWDLPVSDLQKFNCFPEQPAVSEESCRERGCLWEPTTVPGVPTCFYDTIPNYAASNIQYLPTGITVDLTHLTASEAGQAMVPAPSSQDKLSPPAAAAKAASASDTLSATIGFLRLSVTYHTENMLQFKIYDPTNKRYEVPVPLNTPSSPVGSPENCLYDVKIQNNPFGIQIRRKSSSTVIWDSQLPGFTFRDMFLSISTRLPSQYLYGFGETEHTTFRRNISWHTWGMFARDEPPAYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPTPALTYRTTGGILDFYMVLGPTPELVTQQYTELIGRPAMIPYWALGFQLSRYGYQDDYEISSLYVAMMAAQIPYDVQHVDIDYMDRKLDFTLSPSFQNLGPLIEQMKKNGTRFVLVLDPAISGNETQYLTFTRGKESDVFIKWPDNSDIVWGKVWPDLPNVNVDGSLDHETQVKLYKAHVAFPDFLRNSTAAWWKREIEELYRNPREPEKSLKFDGLWINMNEPSNFVNGSVRGCSDEILNNPPYVPYLESRDRGLSSRTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNRAAWDQLKKSIIGMMEFSLFGISYTGADICGFFGDAEYEMCVRWMQLGAFYPFSRNHNTFGTRRQDPVAWDSAFEMFSRKVLQTRYTLLPYLYTLMHKAHAEGSTVVRPLLHEFTEERTTWDIDHQFMLGPAVLISPVLENNTFQVQAYFPRARWYDYSTGSGNESTGEWKVLEAPLDHINLHIRGGYILPWQEPAMNTYSSRQKYMGLIVALDDNGRAEGQLFWDDGQSIDTFENGNYFLVNFTAAQSVLQIQMIHNNYLSDTNSLKVGYIRIWGINSTDITQVTVSYDNQQFMVMNFKSDPYNQTLNIQLTDKIISLEKLTEITWIHSGPIVSTTTMTSTFPMSSLHPPTTSTTAATSVTTSSSTPSSTSTTDSSSAALPMTTTSFPTSATEVSTGTTVPNTSTSFPTNTATDSTSVILPITTMHYPTSATEVSTSVTVPNTTISSPIHTTLDSTDSTLPITDTPYTTSATQVLTSTTVPNATVSSPINTTTDTTDITLTITDTPSTTSATQVSTSTTVPNATISSPINTTTHSTNVTLPVTTTPYITTTAEVSTSTTVPNATISSPINTTTDNTNVTLPVTTMSYITTTAEVSTSTTVPNATVSSPINTTADSTNVTLPVTTMAYTTSTAEVSTTTTFLNATISSPIYTTLDSTNVTLHITDTPYTTSATQVSTSTTVPNATISSPINTTTDSTILTLSVTTMLYPTSATEVSTSTTFPNATISSPINTTTDTTDITLPITDTPYTTSATQVSTSTTVPNATISSPINTTTDGTNVTLPVTDMLYTTSASQVSTSTTVPDATISSPINTTTDTTDITLPITDTPYTTTASQVSTSTTVPNATISSPINTTTDTTDITLPITDTPYTTTASQVSTSTTVPNATISSPINTTTGTTDITFPITDTPYTTTASQVSTSTTVPNATISSPINTTTDTTDITLPITDTPSTTTASQVSTSTTVHNATISSPINTTTDTTDITLPITDTPSTTTASQVSTSTTVPNATISSPINTTTGTTDITFPITDTPYTTTASQVSTSTTVPNATISSPINTTTDTTDITLPITDTPSTTSATQVSTSTTVPNATISSPINTTTDSTNVTLPVTTMPYTTSTAEVSTTTTFPNATISSPINASMDSTDITLPITDTPYTSATQVSASTTASNNTTISSTINTTIDSTNVTLPVTTMPFPKSSTEVSTSTAVSNTTVSSPTNSTV", "length": 2717, "header": "tr|G3N3S2-1|G3N3S2_BOVIN Isoform 1 of Maltase-glucoamylase 2 (putative) OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=3 CANONICAL=G3N3S2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6D9/entry", "sequence": { "sequence": "CKRLGFDPWMARKKLKKFTTLELMLSILLLVVFIITIPIFVLSARDSLESQDPGTTVSPDSGTSTTPGSAECPVVNDSERINCIPDQSPTKATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEGAEKVTAYMPDAVWYDYETGGRVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKDTVANNLYLLCEFSVTQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEANARDVTAYFPRARWYDYYTGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSRQKFLGFKVALDDEGAAEGWLFWDDGQSIDTYEKGLYYLAHFSVSQNMMHSHIIFNNYISNTNPLRLGYFEVWGVGSDSISSVSISASGVVITPTFSYNSTTQVLNIDVTSRNISLHNFTSLMWRSTPNF", "length": 1840, "header": "tr|A0A3Q1M6D9-1|G3N3S2_BOVIN Computationally mapped isoform of Maltase-glucoamylase 2 (putative) OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=3 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105369205, "end_pos": 105284985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068058.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068058.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069293.3", "url": "https://www.ensembl.org/id/ENSBTAP00000069293.3" } ] } }, { "isoform_ac": "A0ABI0NK37-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK37/entry", "sequence": { "sequence": "MNGVTLSDVLFQATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEGAEKVTAYMPDAVWYDYETGGRVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKDTVANNLYLLCEFSVTQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEANARDVTAYFPRARWYDYYTGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSRQKFLGFKVALDDEGAAEGWLFWDDGQSIGDHIIFNNYISNTNPLRLGYFEVWGVGSDSISSVSISASGVVITPTFSYNSTTQVCDQFKVQMVFPNPELWSAIPACSHSQQHPLLQSLSGIPLCSGCLGGQHRNEGKVQSLSPSGIDGLDPYLSCMSSCLQT", "length": 1793, "header": "tr|A0ABI0NK37-1|A0ABI0NK37_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105367506, "end_pos": 105299452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147147.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147147.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104661.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104661.1" } ] } }, { "isoform_ac": "A0ABI0NNM6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNM6/entry", "sequence": { "sequence": "MCVQAESLQSCPIFVTLWTVACQAPLFVGFSRQEYWSVLPFPSPGDLPHPGIKATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEASVPTEWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKGESLCLIVLQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVNKIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEVTMSGIAGSYVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYDRAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEAVSMEGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSDLILPSDAEGSGLIPGEAARISHTSWSKNQNVKQKEYCDKFNKDFKNGPHQKNLKRPSGS", "length": 1683, "header": "tr|A0ABI0NNM6-1|A0ABI0NNM6_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105363889, "end_pos": 105298631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137548.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137548.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104351.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104351.1" } ] } }, { "isoform_ac": "A0ABI0NUW3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUW3/entry", "sequence": { "sequence": "MCVQAESLQSCPIFVTLWTVACQAPLFVGFSRQEYWSVLPFPSPGDLPHPGIKVTSLMFLLLAGGLFTTSATWVLQSHLSMNGVTLSDVLFQATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGKPNCLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEAIVCVPQGGRVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKGRSLCLIVLQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVNKIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEAVSMEGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPVVQQLNHHHHQGLPWWPSDLILPSDAEGSGLIPGEAARISHTSWSKNQNVKQKEYCDKFNKDFKNGPHQKNLKRPSGS", "length": 1734, "header": "tr|A0ABI0NUW3-1|A0ABI0NUW3_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105363889, "end_pos": 105298631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148504.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148504.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107558.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107558.1" } ] } }, { "isoform_ac": "A0ABI0NVJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVJ0/entry", "sequence": { "sequence": "PGLCFFPHCFSSLLSSAAGPGVSRQPELLLLPGPLFDLCPFQFNEEIIKLWGATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEGAEKVTAYMPDAVWYDYETGGRVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKGRSLCLIVLQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEVTMLTSSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGVWTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLENARDVTAYFPRARWYDYYTGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSHIIFNNYISNTNPLRLGYFEVWGVGSDSISSVSISASGVVITPTFSYNSTTQVCDQFKVQMVFPNPELWSAIPACSHSQQHPLLQSLSGIPLCSGCLGGQHRNEGKVQSLSPSGIDGLDPYLSCMSSCLQT", "length": 1789, "header": "tr|A0ABI0NVJ0-1|A0ABI0NVJ0_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105367506, "end_pos": 105297463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145764.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145764.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105493.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105493.1" } ] } }, { "isoform_ac": "A0ABI0NWJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWJ5/entry", "sequence": { "sequence": "MARKKLKKFTTLELMLSILLLVVFIITIPIFVLSARDSLESQDPGTTVSPDSGTSTTPGSAECPVVNDSERINCIPDQSPTKATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEGAEKVTAYMPDAVWYDYETGGRVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKDTVANNLYLLCEFSVTQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEANARDVTAYFPRARWYDYYTGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSRQKFLGFKVALDDEGAAEGWLFWDDGQSIDTYEKGLYYLAHFSVSQNMMHSHIIFNNYISNTNPLRLGYFEVWGVGSDSISSVSISASGVVITPTFSYNSTTQVLVCSPSIHNTSNNNEVHTRTDEQSSGELLVHSNSEAVDCRTDLEY", "length": 1850, "header": "tr|A0ABI0NWJ5-1|A0ABI0NWJ5_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105368418, "end_pos": 105285315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152292.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152292.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105358.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105358.1" } ] } }, { "isoform_ac": "A0ABI0NZ36-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ36/entry", "sequence": { "sequence": "ISKLLNKVNCKLQSHLSMNGVTLSDVLFQATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEGAEKVTAYMPDAVWYDYETGGRVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKDTVANNLYLLCEFSVTQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEANARDVTAYFPRARWYDYYTGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSRQKFLGFKVALDDEGAAEGWLFWDDGQSIGDHRVRVCCGGSTCNNKALASPPLKIFSLDLWHKLRIRTKKSLLWRLHLKNCLKPPKINRPVAHQSCCL", "length": 1746, "header": "tr|A0ABI0NZ36-1|A0ABI0NZ36_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105365713, "end_pos": 105299099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143144.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143144.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106821.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106821.1" } ] } }, { "isoform_ac": "A0ABI0P1D3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1D3/entry", "sequence": { "sequence": "MARKKLKKFTTLELMLSILLLVVFIITIPIFVLSARDSLESQDPGTTVSPDSGTSTTPGSAECPVVNDSERINCIPDQSPTKATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEASVPTELTPNSSLLPQVFGSHINLVSHSRRNPLGLIIALDENKEAKGELFWDDGETKDTVANNLYLLCEFSNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEANARDVTAYFPRARWYDYYTGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSRQKFLGFKVALDDEGAAEGWLFWDDGQSIGDHRVRVCCGGSTCNNKALASPPLKIFSLDLWHKLRIRTKKSLLWRLHLKNCLKPPKINRPVAHQSCCL", "length": 1763, "header": "tr|A0ABI0P1D3-1|A0ABI0P1D3_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105365713, "end_pos": 105285315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153463.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153463.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106780.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106780.1" } ] } }, { "isoform_ac": "A0ABI0P348-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P348/entry", "sequence": { "sequence": "LSMCLQSHLSMNGVTLSDVLFQATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEASVPTELTPNSSLLATMKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKDTVANNLYLLCEFSVTQVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYDRAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSRQKFLGFKVALDDEGAAEGWLFWDDGQSIGDHIIFNNYISNTNPLRLGYFEVWGVGSDSISSVSISASGVCDQFKVQMVFPNPELWSAIPACSHSQQHPLLQSLSGIPLCSGCLGGQHRNEGKVQSLSPSGIDGLDPYLSCMSSCLQT", "length": 1757, "header": "tr|A0ABI0P348-1|A0ABI0P348_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105367506, "end_pos": 105298625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151689.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151689.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105871.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105871.1" } ] } }, { "isoform_ac": "A0ABI0P4D1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D1/entry", "sequence": { "sequence": "MARKKLKKFTTLELMLSILLLVVFIITIPIFVLSARDSLESQDSGTSTTPGSAECPVVNDSERINCIPDQSPTKATCDQRGCCWSPQGTISMPWCYYSKSHGYQVGGDLVNTNAGFTAQLKRLSSPLFGNDVNNVLLTAEYQTSNRFHFKLTDQNQNRYEVPHEHVQPFTGNAASSLTYKVEVSKQPFGIKVIRTSNNRVLFDSSIGPLLFAHQFLQLSIRLPSANVYGLGEHVHQQYRHDMNWKTWPIFARDTTPNGDGTNLYGAQTFFLCLEDASGLSFGVFLLNSNAMEVFLQPTPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPALPSYWALGFHLSRYDYGTLDNMKEVVERNRAAQLPYDVQHADIDYMDARKDFTYDPVAFKGFPEFVKELHNNGQKLVIIVDPAISNNSSLSNPYGPYDRGSDMKIWVNTSDGVTPLIGEVWPGKTVFPDYTNPKCTAWWTNEFELFHSQVEFDGIWIDMNEVANFVDGSVSGCSTSNLNYPPFTPKILDGYLFSKSICMDAVQHWGQHYDVHNLYGYSMAITTAETVKTVFPNKRSLILTRSTFAGSGKFAAHWLGDNAATWSDLRWSIPGMLEFNLFGIPMVGADICGFMLDTSEELCRRWMQLGAFYPFSRNHNGQGYKAQDPASFGPDSLLLNSSRHYLTIRYTLLPYLYTLFYRAHSRGDTVARPLLHEFYQDSNTWDVHQQFLWGPGLLITPVLDEGAEKVTAYMPDAVWYDYETGGRVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPATTTVASRRNPLGLIIALDENKEAKGELFWDDGETKDTVANNLYLLCEFSVTQNRLEVKILQSTYTDPNNLAFKEIKILGTQEPNKVTVKQNGVPIQVSPNVTYDSNLQVALITEIDLVLGGTYTVEWDVKIRDEEKIDCYPDETGVSAENCTARGCAWEESSSHGVPFCYFVNDLYSVSDVQYDSHGASAVITLKTSLYAHSFPSVPVNSLRLTVTYHKDNMLQFKIYDPSNNRYEVPVPLNIPSIPSGTSESQLYAVLIKKNPFGIEIRRKSTGTVIWDSQLLGFTFNDMFIRISTRLPSKYLYGFGETEHTAFRRDLEWNTWGMFSRDQPPGYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTTGGILDFYVVLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDAMVAAQIPYDVQYSDIDYMERQLDFTLDAEFEGFPALITRMRADGMRVIIILDPAISGNETKPYLPFTRGVEDDVFIKDPSDGSIVWGKVWPDFPDVVINSSLDWDSQVEKYRAFVAFPDFFRNSTTTWWKRELRELYTNPREPEKSLKFDGLWIDMNEPASFVNGAVPPGCKDATLNHPPYMPYLESRDRGLSSKTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCARWMQLGAFYPFARNHNTIGTKRQDPVSWNSTFVTISKSVLETRYTLLPYIYTLMHKASTEGSTVVRPLLHEFVSDRVTWDVDSQFLLGPAFLVSPVLEANARDVTAYFPRARWYDYYTGVDIQSRGEWKSLPAPLDHINLHVRGGYVLPWQEPAQNTHLSRQKFLGFKVALDDEGAAEGWLFWDDGQSIDTYEKGLYYLAHFSVSQNMMHSHIIFNNYISNTNPLRLGYFEVWGVGSDSISSVSISASGVVITPTFSYNSTTQVCDQFKVQMENLSLIYFSNSFNYCLSSIIRHPSVKGCCIFSCATKKENKITKA", "length": 1849, "header": "tr|A0ABI0P4D1-1|A0ABI0P4D1_BOVIN Computationally mapped isoform of Maltase-glucoamylase OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=1 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105367642, "end_pos": 105285315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137462.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137462.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106569.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106569.1" } ] } }, { "isoform_ac": "G3N3S2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3S2/entry", "sequence": { "sequence": "MARKLSALEILLIIFIIIVLAVDILFLMLLLEKPSGASFVPECPEIPESERIDCAPGQEVTEDVCRQRYKCCWKPVPDTAIPWCFFPRNWGYEISNLVKNTSTEYEAQLRRLPSPSLFGYDVIDTLFRAEYQTSNRFHFKITDFNNMRYEVPHENVKLFDGNADASNLSYHLEVIHKPFSIKIMRASNKRVLLDTSIGPLQFAQQYLQLSMRLPSANVYGLGEHVHQQYRHNMTWKTWPIFTRDATPTEGMINLYGAHTFFLCLEDTSGFSFGVFLMNSNAMEVTLQPAPAVTYRTIGGILDFYVFLGNTPEQVVQEYLELVGRPFLPPYWSLGFQLSRRNYGGIDGLKNVVNRTREAEIPYDVQYSDIDYMDEKKDFTIDGVAFRGLSGFAEELHKNGLKYVIIMNPGILNNSDYQPYANGSRKRVWILGDKGFVVGQAYPGWTVFPDFTNPDCTEWWKEQFSEFYKTLEFDGVWIEMDEVSSFLQSSDQDCEVNNFNFPPFKPRVLDHLLFARTLCMDTEFHGGFHYDVHSLYGYTMAKATDSAMENIFRNKRRFILSRSTFAGSGKFAAHWLGDNAARWDDLRWSIPGILEFNLFGIPMVGANICGYRENVTEELCRRWMQLGAFYPLSRNHNGPGFRDQDPAAFSENNAMLLESSRYYLNIRYTLLPYLYTLFYRAHTLGETVARPLVHEFYQDPATWEVHEQFLWGPGLLITPVLYEGLNYARAYIPDAIWYDYETQVAIEWRKQFVEMLLPGDRIGLHLRGGYIFPIQQPNTTTETSRKNSLGLIIALDSKREAKGELYWDDGVSKDAVTGNNYILYKFSITSNRLQATIIHANYTDPDKLTFTDIMILGMDKEPTNFTVSLNDVTTSISNVVYTESTKVVNITDLEGLVLGQAFSIQWDLPVSDLQKFNCFPEQPAVSEESCRERGCLWEPTTVPGVPTCFYDTIPNYAASNIQYLPTGITVDLTHLTASEAGQAMVPAPSSQDKLSPPAAAAKAASASDTLSATIGFLRLSVTYHTENMLQFKIYDPTNKRYEVPVPLNTPSSPVGSPENCLYDVKIQNNPFGIQIRRKSSSTVIWDSQLPGFTFRDMFLSISTRLPSQYLYGFGETEHTTFRRNISWHTWGMFARDEPPAYKKNSYGVHPYYMALEEDGSAHGVLLLNSNAMDVTFQPTPALTYRTTGGILDFYMVLGPTPELVTQQYTELIGRPAMIPYWALGFQLSRYGYQDDYEISSLYVAMMAAQIPYDVQHVDIDYMDRKLDFTLSPSFQNLGPLIEQMKKNGTRFVLVLDPAISGNETQYLTFTRGKESDVFIKWPDNSDIVWGKVWPDLPNVNVDGSLDHETQVKLYKAHVAFPDFLRNSTAAWWKREIEELYRNPREPEKSLKFDGLWINMNEPSNFVNGSVRGCSDEILNNPPYVPYLESRDRGLSSRTLCMESQQVLPDGSPVRHYDVHSLYGWAQTRPTYEAVQEVTGQRGIVITRSTFPSSGRWGGHWLGDNRAAWDQLKKSIIGMMEFSLFGISYTGADICGFFGDAEYEMCVRWMQLGAFYPFSRNHNTFGTRRQDPVAWDSAFEMFSRKVLQTRYTLLPYLYTLMHKAHAEGSTVVRPLLHEFTEERTTWDIDHQFMLGPAVLISPVLENNTFQVQAYFPRARWYDYSTGSGNESTGEWKVLEAPLDHINLHIRGGYILPWQEPAMNTYSSRQKYMGLIVALDDNGRAEGQLFWDDGQSIDTFENGNYFLVNFTAAQSVLQIQMIHNNYLSDTNSLKVGYIRIWGINSTDITQVTVSYDNQQFMVMNFKSDPYNQTLNIQLTDKIISLEKLTEITWIHSGPIVSTTTMTSTFPMSSLHPPTTSTTAATSVTTSSSTPSSTSTTDSSSAALPMTTTSFPTSATEVSTGTTVPNTSTSFPTNTATDSTSVILPITTMHYPTSATEVSTSVTVPNTTISSPIHTTLDSTDSTLPITDTPYTTSATQVLTSTTVPNATVSSPINTTTDTTDITLTITDTPSTTSATQVSTSTTVPNATISSPINTTTHSTNVTLPVTTTPYITTTAEVSTSTTVPNATISSPINTTTDNTNVTLPVTTMSYITTTAEVSTSTTVPNATVSSPINTTADSTNVTLPVTTMAYTTSTAEVSTTTTFLNATISSPIYTTLDSTNVTLHITDTPYTTSATQVSTSTTVPNATISSPINTTTDSTILTLSVTTMLYPTSATEVSTSTTFPNATISSPINTTTDTTDITLPITDTPYTTSATQVSTSTTVPNATISSPINTTTDGTNVTLPVTDMLYTTSASQVSTSTTVPDATISSPINTTTDTTDITLPITDTPYTTTASQVSTSTTVPNATISSPINTTTDTTDITLPITDTPYTTTASQVSTSTTVPNATISSPINTTTGTTDITFPITDTPYTTTASQVSTSTTVPNATISSPINTTTDTTDITLPITDTPSTTTASQVSTSTTVHNATISSPINTTTDTTDITLPITDTPSTTTASQVSTSTTVPNATISSPINTTTGTTDITFPITDTPYTTTASQVSTSTTVPNATISSPINTTTDTTDITLPITDTPSTTSATQVSTSTTVPNATISSPINTTTDSTNVTLPVTTMPYTTSTAEVSTTTTFPNATISSPINASMDSTDITLPITDTPYTSATQVSASTTASNNTTISSTINTTIDSTNVTLPVTTMPFPKSSTEVSTSTAVSNTTVSSPTNSTV", "length": 2717, "header": "tr|G3N3S2-1|G3N3S2_BOVIN Isoform 1 of Maltase-glucoamylase 2 (putative) OS=Bos taurus OX=9913 GN=MGAM PE=3 SV=3 CANONICAL=G3N3S2-1" }, "locus": { "chromosome": "4", "start_pos": 105469919, "end_pos": 105380415, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064122.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064122.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056581.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056581.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1178, "start_aa": "Thr", "end_pos": 1178, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1178", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1199, "start_aa": "Thr", "end_pos": 1199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1199", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1870, "start_aa": "Thr", "end_pos": 1870, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1870", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100336421", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336421", "resource": "KEGG Pathway" }, { "id": "R-BTA-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" }, { "name": "alpha-glucosidase activity", "id": "GO:0090599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090599", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" }, { "name": "alpha-1,4-glucosidase activity", "id": "GO:0004558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004558", "evidence": [ { "database": "UniProtKB", "id": "G3N3S2", "url": "https://www.uniprot.org/uniprotkb/G3N3S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1123, "end_pos": 1125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1286, "end_pos": 1288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1301, "end_pos": 1303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1365, "end_pos": 1367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1406, "end_pos": 1408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1644, "end_pos": 1646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1667, "end_pos": 1669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1746, "end_pos": 1748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1781, "end_pos": 1783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1808, "end_pos": 1810, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1906, "end_pos": 1908, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1946, "end_pos": 1948, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1986, "end_pos": 1988, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1994, "end_pos": 1996, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2026, "end_pos": 2028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2034, "end_pos": 2036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2041, "end_pos": 2043, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2066, "end_pos": 2068, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2074, "end_pos": 2076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2081, "end_pos": 2083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2106, "end_pos": 2108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2114, "end_pos": 2116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2121, "end_pos": 2123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2146, "end_pos": 2148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2161, "end_pos": 2163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2186, "end_pos": 2188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2194, "end_pos": 2196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2226, "end_pos": 2228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2234, "end_pos": 2236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2266, "end_pos": 2268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2274, "end_pos": 2276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2281, "end_pos": 2283, "annotation": "n_glycosylation_sequon" 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} ] } }, { "isoform_ac": "G3MWK7-1", "url": "https://www.uniprot.org/uniprotkb/G3MWK7/entry", "sequence": { "sequence": "MEAPNAVLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRMKMQKGIPLNDEDRIPWLCKLHDVLRRDVASGQHVVLACSALKKVYRDILIQGKDDAPLKCDDLGKEEKPVEVKLLVVHLTGSFDIISGRLLRRKDHFMPPELLQSQSDTLETPSAPESFIQINVDKNLSEIIATIMETLK", "length": 185, "header": "tr|G3MWK7-1|G3MWK7_BOVIN Isoform 1 of Gluconokinase OS=Bos taurus OX=9913 GN=IDNK PE=3 SV=2 CANONICAL=G3MWK7-1" }, "locus": { "chromosome": "8", "start_pos": 76849971, "end_pos": 76834286, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064590.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064590.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053908.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053908.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100297815", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297815", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2X5-1", "protein_name": "Gluconokinase", "gene_name": "IDNK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPNVLLVMGVSGSGKSTIGTLLASELGWKFYDADDYHPEENRMKMGKGMPLNDQDRIPWLCNLHDILQRDVASGQHVVLACSALKKGYRDILIHGKNSAPLKCDELGKEEKPAEVKLLVVHLTGSFEVISGRLLRRQGHFMPPKLLQSQFDTLEPPSAPENFIQISVDKSLSEIIAIIMESLKRNENHLYE", "length": 193 }, "evidence": [ { "id": "G3MWK7", "url": "https://omabrowser.org/oma/group/G3MWK7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q03786-1", "protein_name": "Probable gluconokinase", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTEKHKTMGKFKVIVLAGTAGTGKSTIAGELIHEFKDIYPDLKFIEGDDLHPPANVEKMTRGIPLNDDDRWDWLKKVAVESTKAAASTKEHLSIVACSSLKKKYRDLIRHTCPESEFHFIFLYASKIEVLKRLKTRKGHFMKADMMESQFRDLELPDINDETDCDIVPLDFKTFYQIEKDVIQVVKSKVLNIE", "length": 193 }, "evidence": [ { "id": "G3MWK7", "url": "https://omabrowser.org/oma/group/G3MWK7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54PI5-1", "protein_name": "Probable gluconokinase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTNLDNNNLNEEIKNKLEKQQNQKEQKLIIVIMGVSGSGKTTIGNAIASSLGCGFNDADEFHSEENKEKMRSGIPLNDDDRKPWLSSINKRMIEFLNNENDGANDHVFTCSALKSTYRDQISNNINKDNLLFILLQGSKQLLSERLQNRKNHFFNPNLLDSQLSILELPTQSELSNHHYAFIDISNSVDEIVEEIFNYLK", "length": 200 }, "evidence": [ { "id": "G3MWK7", "url": "https://omabrowser.org/oma/group/G3MWK7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5T6J7-1", "protein_name": "Gluconokinase", "gene_name": "IDNK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPGALLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRRKMGKGIPLNDQDRIPWLCNLHDILLRDVASGQRVVLACSALKKTYRDILTQGKDGVALKCEESGKEAKQAEMQLLVVHLSGSFEVISGRLLKREGHFMPPELLQSQFETLEPPAAPENFIQISVDKNVSEIIATIMETLKMK", "length": 187 }, "evidence": [ { "id": "G3MWK7", "url": "https://omabrowser.org/oma/group/G3MWK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0J8-1", "protein_name": "Gluconokinase", "gene_name": "Idnk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAPGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQPVVLACSALKKTYRDILIRGGSDAPLKSDDSAKEPLAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPENFIQVSVDKSLPEITAAVMEALK", "length": 184 }, "evidence": [ { "id": "G3MWK7", "url": "https://omabrowser.org/oma/group/G3MWK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "gluconokinase activity", "id": "GO:0046316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046316", "evidence": [ { "database": "UniProtKB", "id": "G3MWK7", "url": "https://www.uniprot.org/uniprotkb/G3MWK7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MWK7", "url": "https://www.uniprot.org/uniprotkb/G3MWK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "G3MWK7", "url": "https://www.uniprot.org/uniprotkb/G3MWK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19433", "name": "", "equation": "D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MWK7-1" ], "evidence": [ { "id": "19433", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19433" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "G3MWK7", "gene_name": "IDNK", "activity": [ { "ec_number": "2.7.1.12", "activity": "D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+).", "evidence": [ { "id": "G3MWK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWK7" } ] }, { "ec_number": "2.7.1.12", "activity": "", "evidence": [ { "id": "G3MWK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWK7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWK7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 185, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWK7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWK7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.12", "ec_name": "D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+).", "evidence": [ { "id": "2.7.1.12", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.12" }, { "id": "2.7.1.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RUH3-1", "uniprot_ac": "F6RUH3", "uniprot_id": "F6RUH3_BOVIN", "mass": { "chemical_mass": 34908.0, "monoisotopic_mass": 34908.0 }, "refseq": {}, "gene_names": [ { "name": "HSD17B3", "type": "recommended", "evidence": [ { "id": "F6RUH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ] } ], "protein_names": [ { "name": "17beta-estradiol 17-dehydrogenase", "type": "recommended", "evidence": [ { "id": "F6RUH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUH3/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.62", "type": "synonym", "evidence": [ { "id": "F6RUH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HSD17B3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3", "locus": { "chromosome": "8", "start_pos": 82961057, "end_pos": 83014357, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016867", "url": "https://www.ensembl.org/id/ENSBTAG00000016867" } ] } } ], "crossref": [ { "id": "F6RUH3", "url": "https://alphafold.ebi.ac.uk/entry/F6RUH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016867", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016867", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05356", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05356", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616934", "url": "https://www.ncbi.nlm.nih.gov/gene/616934", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GNMPIPN", "url": "https://omabrowser.org/oma/group/GNMPIPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MC83", "url": "https://www.orthodb.org/?gene=A0A3Q1MC83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RUH3", "url": "https://www.orthodb.org/?gene=F6RUH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43899:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43899:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-193048", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75876", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MC83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MC83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RUH3-1", "url": "https://www.uniprot.org/uniprotkb/F6RUH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEALEQFFIFVGLLVCLVYLMKCVRFSKCIFLHFWKVLPRSFLKSVGEWAVITGAGDGIGKAYSFELARQGFNVVLISRTLEKLQAIAAEIELTIGSTVKIIQADFAKDDIYDYIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTSDDIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSASKAFVCTFSKALQAEYKDKGIIIQVLTPYAISTPMTKYLSTNMITKTADEFVKESLNYVTIGDETCGCLTHEILAVILSLIPSWAFYSSVFQKMLLTRYVDYLKKNANIR", "length": 310, "header": "tr|F6RUH3-1|F6RUH3_BOVIN Isoform 1 of 17beta-estradiol 17-dehydrogenase OS=Bos taurus OX=9913 GN=HSD17B3 PE=3 SV=1 CANONICAL=F6RUH3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MC83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC83/entry", "sequence": { "sequence": "MKEALEQFFIFVGLLVCLVYLMKCVRFSKCIFLHFWKVLPRSFLKSVGEWAVITGAGDGIGKAYSFELARQGFNVVLISRTLEKLQAIAAEIELTIGSTVKIIQADFAKDDIYDYIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTSDDIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSASKAFVCTFSKALQAEYKDKGIIIQAVILSLIPSWAFYSSVFQKMLLTRYVDYLKKNANIR", "length": 260, "header": "tr|A0A3Q1MC83-1|F6RUH3_BOVIN Computationally mapped isoform of 17beta-estradiol 17-dehydrogenase OS=Bos taurus OX=9913 GN=HSD17B3 PE=3 SV=2 CANONICAL=F6RUH3-1" }, "locus": { "chromosome": "8", "start_pos": 83014298, "end_pos": 82961687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074161.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074161.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067930.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067930.2" } ] } }, { "isoform_ac": "F6RUH3-1", "url": "https://www.uniprot.org/uniprotkb/F6RUH3/entry", "sequence": { "sequence": "MKEALEQFFIFVGLLVCLVYLMKCVRFSKCIFLHFWKVLPRSFLKSVGEWAVITGAGDGIGKAYSFELARQGFNVVLISRTLEKLQAIAAEIELTIGSTVKIIQADFAKDDIYDYIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTSDDIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSASKAFVCTFSKALQAEYKDKGIIIQVLTPYAISTPMTKYLSTNMITKTADEFVKESLNYVTIGDETCGCLTHEILAVILSLIPSWAFYSSVFQKMLLTRYVDYLKKNANIR", "length": 310, "header": "tr|F6RUH3-1|F6RUH3_BOVIN Isoform 1 of 17beta-estradiol 17-dehydrogenase OS=Bos taurus OX=9913 GN=HSD17B3 PE=3 SV=1 CANONICAL=F6RUH3-1" }, "locus": { "chromosome": "8", "start_pos": 83014298, "end_pos": 82961687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022431.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022431.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022431.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022431.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-193048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193048", "resource": "Reactome", "description": "Androgen biosynthesis" }, { "id": "R-BTA-75876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75876", "resource": "Reactome", "description": "Synthesis of very long-chain fatty acyl-CoAs" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S4L6-1", "protein_name": "17beta-estradiol 17-dehydrogenase", "gene_name": "HSD17B3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDILGQFFIFVGLLVCLVYLAKCVRFCKCIFLNFWRVSPRSFLMSMGQWAVITGAGDGIGKAYSFELARQGLNVVLISRTLEKLQTIAAEIEWTIGTSVKIIQADFTKDDIYEDIKEKLKGLEIGILVNNVGMLPNLLPSHFLNTPDNIQSVIHCNITSVVKMTQLILKHMESRQKGLILNISSGVALFPWPLYSMYSSSKAFVCTFSKALQAEYEAKGIIIQVLTPHAVSTQMTNYLNTNMITKTADEFVKESLKYVTIGDETCGCLAHEILAIILSLIPSRVFYSSTFQKMVLTHYVKYLKQNFNLR", "length": 310 }, "evidence": [ { "id": "F6RUH3", "url": "https://omabrowser.org/oma/group/F6RUH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O54939-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "Hsd17b3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQFLLSVGLLVCLVCLVKCVRFSRYLFLSFCKALPGSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQVISEEIERTTGSRVKVVQADFTREDIYDHIEEQLKGLEIGVLVNNVGMLPNLLPSHFLSTSGESQSVIHCNITSVVKMTQLVLKHMESRRRGLILNISSGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGIIIQVLTPYSVSTPMTKYLNTSRVTKTADEFVKESLKYVTIGAETCGCLAHEILAIILNLIPSRIFYSSTTQRFLLKQFSDYLKSNISNR", "length": 306 }, "evidence": [ { "id": "F6RUH3", "url": "https://omabrowser.org/oma/group/F6RUH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYVAYLKLNTKVR", "length": 310 }, "evidence": [ { "id": "F6RUH3", "url": "https://omabrowser.org/oma/group/F6RUH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70385-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "Hsd17b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLFIAAGLFVGLVCLVKCMRFSQHLFLRFCKALPSSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGMLPSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTKYLNNKMTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLLTRYSDYLKRNISNR", "length": 305 }, "evidence": [ { "id": "F6RUH3", "url": "https://omabrowser.org/oma/group/F6RUH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6QA32-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "hsd17b3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLTEIIFVLTGTCAILVFGGKIASLIMMLITKLFCPLPEAFFTSLGKWAVITGGSDGIGRAYAEELSKQGMSVIIISRNQEKLDRAAKKIELNTGGKVKVIAADFTKDDIYGHITENIEGLDIGVLVNNVGILPSQIPCKLLETSDLEERIYDIVNCNVKSMVKMCRIVLPGMQQRRRGVILNVSSGIAKIPCPIYTLYAASKVFVERFSQGLQAEYISKGIIIQTVAPFGVSTAMTGHQKPDMVTFTAEEFVRSSLKYLKTGDQTYGSITHTLLGRIVQSIPTWVLQSETFQHHFQEYVKNRDRR", "length": 307 }, "evidence": [ { "id": "F6RUH3", "url": "https://omabrowser.org/oma/group/F6RUH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "steroid biosynthetic process", "id": "GO:0006694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006694", "evidence": [ { "database": "UniProtKB", "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ], "pmid": "" }, { "name": "androgen biosynthetic process", "id": "GO:0006702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006702", "evidence": [ { "database": "UniProtKB", "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ], "pmid": "" }, { "name": "testosterone dehydrogenase (NADP+) activity", "id": "GO:0047045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047045", "evidence": [ { "database": "UniProtKB", "id": "F6RUH3", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-193064", "name": "HSD17B3-like proteins reducde ANDST to TEST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RUH3-1" ], "evidence": [ { "id": "R-BTA-193064", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193064" } ] }, { "id": "R-BTA-548818", "name": "HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-548812" ], "output_participant_list": [ "R-ALL-548836" ], "enzyme_list": [ "F6RUH3-1" ], "evidence": [ { "id": "R-BTA-548818", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-548818" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-548812", "participant_name": "3OOD-CoA [cytosol]", "crossref": [ { "id": "71407", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-548836", "participant_name": "3HODC-CoA [cytosol]", "crossref": [ { "id": "71408", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F6RUH3", "gene_name": "HSD17B3", "activity": [ { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "F6RUH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "F6RUH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUH3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RUH3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RUH3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RUH3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.62", "ec_name": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "1.1.1.62", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62" }, { "id": "1.1.1.62", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.62" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 157, "end_pos": 159 }, { "start_pos": 182, "end_pos": 184 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6L5-1", "uniprot_ac": "G3X6L5", "uniprot_id": "G3X6L5_BOVIN", "mass": { "chemical_mass": 21416.0, "monoisotopic_mass": 21416.0 }, "refseq": { "ac": "XP_005217479", "name": "ADP-ribosylation factor-like protein 8A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217479" }, "gene_names": [ { "name": "ARL8A", "type": "recommended", "evidence": [ { "id": "G3X6L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6L5" } ] }, { "name": "ARL8A", "type": "synonym", "evidence": [ { "id": "XP_005217479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217479" } ] } ], "protein_names": [ { "name": "ADP ribosylation factor like GTPase 8A", "type": "synonym", "evidence": [ { "id": "G3X6L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6L5/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor-like protein 8A", "type": "synonym", "evidence": [ { "id": "XP_005217479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217479" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6L5", "url": "https://www.uniprot.org/uniprotkb/G3X6L5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARL8A", "url": "https://www.uniprot.org/uniprotkb/G3X6L5", "locus": { "chromosome": "16", "start_pos": 80437424, "end_pos": 80429807, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006574", "url": "https://www.ensembl.org/id/ENSBTAG00000006574" } ] } } ], "crossref": [ { "id": "G3X6L5", "url": "https://alphafold.ebi.ac.uk/entry/G3X6L5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006574", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006574", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101906089", "url": "https://www.ncbi.nlm.nih.gov/gene/101906089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101906089", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101906089", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RFRSEWG", "url": "https://omabrowser.org/oma/group/RFRSEWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6L5", "url": "https://www.orthodb.org/?gene=G3X6L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45732:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45732:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005217479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6L5", "url": "https://www.uniprot.org/uniprotkb/G3X6L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6L5-1", "url": "https://www.uniprot.org/uniprotkb/G3X6L5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS", "length": 186, "header": "tr|G3X6L5-1|G3X6L5_BOVIN Isoform 1 of ADP ribosylation factor like GTPase 8A OS=Bos taurus OX=9913 GN=ARL8A PE=3 SV=2 CANONICAL=G3X6L5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCZ8/entry", "sequence": { "sequence": "MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPEPVCHPGPRDLLLFHLLQREGQHRHHSTVAYPALKVAEELRPRPRLGPGAASQPEAELPLPLRPPKPTLPTPCGEGPRGPQSPVLLRFELLI", "length": 216, "header": "tr|A0A3Q1MCZ8-1|G3X6L5_BOVIN Computationally mapped isoform of ADP ribosylation factor like GTPase 8A OS=Bos taurus OX=9913 GN=ARL8A PE=3 SV=2 CANONICAL=G3X6L5-1" }, "locus": { "chromosome": "16", "start_pos": 80436420, "end_pos": 80430006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067584.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067584.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068254.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068254.2" } ] } }, { "isoform_ac": "G3X6L5-1", "url": "https://www.uniprot.org/uniprotkb/G3X6L5/entry", "sequence": { "sequence": "MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS", "length": 186, "header": "tr|G3X6L5-1|G3X6L5_BOVIN Isoform 1 of ADP ribosylation factor like GTPase 8A OS=Bos taurus OX=9913 GN=ARL8A PE=3 SV=2 CANONICAL=G3X6L5-1" }, "locus": { "chromosome": "16", "start_pos": 80436262, "end_pos": 80430006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008635.8", "url": "https://www.ensembl.org/id/ENSBTAT00000008635.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008635.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008635.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101906089", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101906089", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2L0-1", "protein_name": "ADP ribosylation factor like GTPase 8A", "gene_name": "ARL8A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS", "length": 186 }, "evidence": [ { "id": "G3X6L5", "url": "https://omabrowser.org/oma/group/G3X6L5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZPP2-1", "protein_name": "ADP-ribosylation factor like GTPase 8A", "gene_name": "Arl8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLAGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS", "length": 186 }, "evidence": [ { "id": "G3X6L5", "url": "https://omabrowser.org/oma/group/G3X6L5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8W2P1-1", "protein_name": "ADP-ribosylation factor-like protein 8A", "gene_name": "arl8a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADPEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLPGALDEKELIERMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSRTRRS", "length": 186 }, "evidence": [ { "id": "G3X6L5", "url": "https://omabrowser.org/oma/group/G3X6L5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5ZKQ8-1", "protein_name": "ADP-ribosylation 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"https://www.uniprot.org/uniprotkb/A0A3Q1LQR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0P4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3N3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF40", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF40-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML95", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXD5", "url": "https://www.uniprot.org/uniprotkb/G3MXD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXD5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLVEGCFEGYNATVLAYGQTGAGKTYTMGTGFDVATAEEEQGIIPRAIAHLFGGIAERKQRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSARDPDARHRKSHIKIHEDASGSIYTTGVTSRLISSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCARPDLVNEAVSGLPDSAPPASEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENALLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLSASPAAPASSMEDASEVIRRAKQDLERLKKKEIRQRRKSPEKEAFKKRAKLQQENSEETDDNEAEEEDEEREESGCEEEDGREDEDEDSGSEESLADSDSDPEEKEVNYQVDLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRTREIAQLRKEQRRQEFQIRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGPKSPMLDSGAEVSASTTSSEAESGARSVSSIVRQWDRKINHFLGSHSAPTVPGARPARKKFQKKGASQSFSKAARLKWQSLERRILDIVMQRMTIVNLEADMERLIKKREELSLMQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDSIGDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDIAGSSQNHVLLDALREKAEAHPELQALIHNVQQENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDVSTKNITKSLASLVEIKEDGVGFSVRDPYYRDKVSRTISLPTRGSTFPRQSRGAETSPLTRRKSYDRGQPMRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSEVLRGIITPVGGAKGARTAPLQCVSMAEGHTKPVLCVDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCRHSGLVFSVSASYIKVWDIRDSAKCVRTLTSSGQVVSGDACAAASTRTVTSGQGEHQINQIALSPAGSMLYAASGNAVRVWELSRFQPIAKLTGHIGPVMCLTAAQTAGQRDLVVTGSKDHYVKMFELGEGVTGTIGPTHNFEPPHYDGIECLAIQGDVLFSGSRDNGVKKWDLEHQELVQQIPTAHKDWVCALAFVPGRPMLLSACRAGVVKVWNVDNFTPIGEIKGHDSPINAICTNSRHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRATTMP", "length": 1631, "header": "tr|G3MXD5-1|G3MXD5_BOVIN Isoform 1 of Kinesin family member 21B OS=Bos taurus OX=9913 GN=KIF21B PE=3 SV=3 CANONICAL=G3MXD5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQR3/entry", "sequence": { "sequence": "MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLVEGCFEGYNATVLAYGQTGAGKTYTMGTGFDVATAEEEQGIIPRAIAHLFGGIAERKQRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSARDPDARHRKSHIKIHEDASGSIYTTGVTSRLISSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCARPDLVNEAVSGLPDSAPPASEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENALLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLSASPAAPASSMEDASEVIRRAKQDLERLKKKEIRQRRKSPEKEAFKKRAKLQQENSEETDDNEAEEEDEEREESGCEEEDGREDEDEDSGSEESLADSDSDPEEKEVNYQVDLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRTREIAQLRKEQRRQEFQIRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGPKSPMLDSGAEVSASTTSSEAESGARSVSSIVRQWDRKINHFLGSHSAPTVPGARPARKKFQKKGASQSFSKAARLKWQSLERRILDIVMQRMTIVNLEADMERLIKKREELSLMQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDSIGDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDIAGSSQNHVLLDALREKAEAHPELQALIHNVQQENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDVSTKNITKSLASLVEIKEDGVGFSVRDPYYRDKVSRTISLPTRGSTFPRQSRGAETSPLTRRKSYDRGQPMRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKGIITPVGGAKGARTAPLQCVSMAEGHTKPVLCVDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCRHSGLVFSVSASYIKVWDIRDSAKCVRTLTSSGQVVSGDACAAASTRTVTSGQGEHQINQIALSPAGSMLYAASGNAVRVWELSRFQPIAKLTGHIGPVMCLTAAQTAGQRDLVVTGSKDHYVKMFELGEGVTGTIGPTHNFEPPHYDGIECLAIQGDVLFSGSRDNGVKKWDLEHQELVQQIPTAHKDWVCALAFVPGRPMLLSACRAGVVKVWNVDNFTPIGEIKGHDSPINAICTNSRHIFTASSDLTVKFWSARRLPSGPH", "length": 1603, "header": "tr|A0A3Q1LQR3-1|A0A3Q1LQR3_BOVIN Computationally mapped isoform of Kinesin family member 21B OS=Bos taurus OX=9913 GN=KIF21B PE=3 SV=2 CANONICAL=G3MXD5-1" }, "locus": { "chromosome": "16", "start_pos": 79591021, "end_pos": 79548614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066756.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066756.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059442.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059442.2" } ] } }, { "isoform_ac": "A0A3Q1M0P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0P4/entry", "sequence": { "sequence": "MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLVEGCFEGYNATVLAYGQTGAGKTYTMGTGFDVATAEEEQGIIPRAIAHLFGGIAERKQRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSARDPDARHRKSHIKIHEDASGSIYTTGVTSRLISSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCARPDLVNEAVSGLPDSAPPASEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENALLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLSASPAAPASSMEDASEVIRRAKQDLERLKKKEIRQRRKSPEKEAFKKRAKLQQENSEETDDNEAEEEDEEREESGCEEEDGREDEDEDSGSEESLADSDSDPEEKEVNYQVDLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRTREIAQLRKEQRRQEFQIRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGPKSPMLDSGAEVSASTTSSEAESGARSVSSIVRQWDRKINHFLGSHSAPTVPGARPARKKFQKKGASQSFSKAARLKWQSLERRILDIVMQRMTIVNLEADMERLIKKREELSLMQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDSIGDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDIAGSSQNHVLLDALREKAEAHPELQALIHNVQQENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDVSTKNITKSLASLVEIKEDGVGFSVRDPYYRDKVSRTISLPTRGSTFPRQSRGAETSPLTRRKSYDRGQPMRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSEVLRGIITPVGGAKGARTAPLQCVSMAEGHTKPVLCVDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCRHSGLVFSVSASYIKVWDIRDSAKCVRTLTSSGQVVSGDACAAASTRTVTSGQGEHQINQIALSPAGSMLYAASGNAVRVWELSRFQPIAKLTGHIGPVMCLTAAQTAGQRDLVVTGSKDHYVKMFELGEGVTGTIGPTHNFEPPHYDGIECLAIQGDVLFSGSRDNGVKKWDLEHQELVQQIPTAHKDWVCALAFVPGRPMLLSACRAGVVKVWNVDNFTPIGEIKGHDSPINAICTNSRHIFTASSDLTVKFWSARRLPSGPH", "length": 1616, "header": "tr|A0A3Q1M0P4-1|A0A3Q1M0P4_BOVIN Computationally mapped isoform of Kinesin family member 21B OS=Bos taurus OX=9913 GN=KIF21B PE=3 SV=2 CANONICAL=G3MXD5-1" }, "locus": { "chromosome": "16", "start_pos": 79591021, "end_pos": 79548614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073200.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073200.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066795.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066795.2" } ] } }, { "isoform_ac": "A0A3Q1M3N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3N3/entry", "sequence": { "sequence": "MAGQGDCCVKVAVRPAGVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLVEGCFEGYNATVLAYGQTGAGKTYTMGTGFDVATAEEEQGIIPRAIAHLFGGIAERKQRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSARDPDARHRKSHIKIHEDASGSIYTTGVTSRLISSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCARPDLVNEAVSGLPDSAPPASEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENALLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLSASPAAPASSMEDASEVIRRAKQDLERLKKKEIRQRRKSPEKEAFKKRAKLQQENSEETDDNEAEEEDEEREESGCEEEDGREDEDEDSGSEESLADSDSDPEEKEVNYQVDLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRTREIAQLRKEQRRQEFQIRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGPKSPMLDSGAEVSASTTSSEAESGARSVSSIVRQWDRKINHFLGSHSAPTVPGARPARKKFQKKGASQSFSKAARLKWQSLERRILDIVMQRMTIVNLEADMERLIKKREELSLMQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDSIGDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDIAGSSQNHVLLDALREKAEAHPELQALIHNVQQENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDVSTKNITKSLASLVEIKEDGVGFSVRDPYYRDKVSRTISLPTRGSTFPRQSRGAETSPLTRRKSYDRGQPMRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSEVLRGIITPVGGAKGARTAPLQCVSMAEGHTKPVLCVDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCRHSGLVFSVSASYIKVWDIRDSAKCVRTLTSSGQVVSGDACAAASTRTVTSGQGEHQINQIALSPAGSMLYAASGNAVRVWELSRFQPIAKLTGHIGPVMCLTAAQTAGQRDLVVTGSKDHYVKMFELGEGVTGTIGPTHNFEPPHYDGIECLAIQGDVLFSGSRDNGVKKWDLEHQELVQQIPTAHKDWVCALAFVPGRPMLLSACRAGVVKVWNVDNFTPIGEIKGHDSPINAICTNSRHIFTASSDLTVKFWSARRLPSGPH", "length": 1621, "header": "tr|A0A3Q1M3N3-1|A0A3Q1M3N3_BOVIN Computationally mapped isoform of Kinesin family member 21B OS=Bos taurus OX=9913 GN=KIF21B PE=3 SV=2 CANONICAL=G3MXD5-1" }, "locus": { "chromosome": "16", "start_pos": 79591021, "end_pos": 79548614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074175.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074175.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064775.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064775.2" } ] } }, { "isoform_ac": "A0A3Q1MF40-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF40/entry", "sequence": { "sequence": "MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLVEGCFEGYNATVLAYGQTGAGKTYTMGTGFDVATAEEEQGIIPRAIAHLFGGIAERKQRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSARDPDARHRKSHIKIHEDASGSIYTTGVTSRLISSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCARPDLVNEAVSGLPDSAPPASEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENALLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLSASPAAPASSMEDASEVIRRAKQDLERLKKKEIRQRRKSPEKEAFKKRAKLQQENSEETDDNEAEEEDEEREESGCEEEDGREDEDEDSGSEESLADSDSDPEEKEVNYQVDLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRTREIAQLRKEQRRQEFQIRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGPKSPMLDSGAEVSASTTSSEAESGARSVSSIVRQWDRKINHFLGSHSAPTVPGARPARKKFQKKGASQSFSKAARLKWQSLERRILDIVMQRMTIVNLEADMERLIKKREELSLMQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDSIGDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDIAGSSQNHVLLDALREKAEAHPELQALIHNVQQENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDVSTKNITKSLASLVEIKEDGVGFSVRDPYYRDKVSRTISLPTRGSTFPRQSRGAETSPLTRRKSYDRGQPMRGIITPVGGAKGARTAPLQCVSMAEGHTKPVLCVDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCRHSGLVFSVSASYIKVWDIRDSAKCVRTLTSSGQVVSGDACAAASTRTVTSGQGEHQINQIALSPAGSMLYAASGNAVRVWELSRFQPIAKLTGHIGPVMCLTAAQTAGQRDLVVTGSKDHYVKMFELGEGVTGTIGPTHNFEPPHYDGIECLAIQGDVLFSGSRDNGVKKWDLEHQELVQQIPTAHKDWVCALAFVPGRPMLLSACRAGVVKVWNVDNFTPIGEIKGHDSPINAICTNSRHIFTASSDLTVKFWSARRLPSGPH", "length": 1565, "header": "tr|A0A3Q1MF40-1|G3MXD5_BOVIN Computationally mapped isoform of Kinesin family member 21B OS=Bos taurus OX=9913 GN=KIF21B PE=3 SV=2 CANONICAL=G3MXD5-1" }, "locus": { "chromosome": "16", "start_pos": 79591021, "end_pos": 79548614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074664.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074664.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069143.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069143.2" } ] } }, { "isoform_ac": "A0A3Q1ML95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML95/entry", "sequence": { "sequence": "MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLVEGCFEGYNATVLAYGQTGAGKTYTMGTGFDVATAEEEQGIIPRAIAHLFGGIAERKQRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSARDPDARHRKSHIKIHEDASGSIYTTGVTSRLISSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCARPDLVNEAVSGLPDSAPPASEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENALLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLSASPAAPASSMEDASEVIRRAKQDLERLKKKEIRQRRKSPEKEAFKKRAKLQQENSEETDDNEAEEEDEEREESGCEEEDGREDEDEDSGSEESLADSDSDPEEKEVNYQVDLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRTREIAQLRKEQRRQEFQIRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGPKSPMLDSGAEVSASTTSSEAESGARSVSSIVRQWDRKINHFLGSHSAPTVPGARPARKKFQKKGASQSFSKAARLKWQSLERRILDIVMQRMTIVNLEADMERLIKKREELSLMQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDSIGDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDIAGSSQNHVLLDALREKAEAHPELQALIHNVQQENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDVSTKNITKSLASLVEIKEDGVGFSVRDPYYRDKVSRTISLPTRGSTFPRQSRGAETSPLTRRKSYDRGQPMRSDDSDSSLSEVLRGIITPVGGAKGARTAPLQCVSMAEGHTKPVLCVDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCRHSGLVFSVSASYIKVWDIRDSAKCVRTLTSSGQVVSGDACAAASTRTVTSGQGEHQINQIALSPAGSMLYAASGNAVRVWELSRFQPIAKLTGHIGPVMCLTAAQTAGQRDLVVTGSKDHYVKMFELGEGVTGTIGPTHNFEPPHYDGIECLAIQGDVLFSGSRDNGVKKWDLEHQELVQQIPTAHKDWVCALAFVPGRPMLLSACRAGVVKVWNVDNFTPIGEIKGHDSPINAICTNSRHIFTASSDLTVKFWSARRLPSGPH", "length": 1578, "header": "tr|A0A3Q1ML95-1|G3MXD5_BOVIN Computationally mapped isoform of Kinesin family member 21B OS=Bos taurus OX=9913 GN=KIF21B PE=3 SV=2 CANONICAL=G3MXD5-1" }, "locus": { "chromosome": "16", "start_pos": 79591021, "end_pos": 79548614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067799.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067799.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071757.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071757.2" } ] } }, { "isoform_ac": "G3MXD5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXD5/entry", "sequence": { "sequence": 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"length": 1631, "header": "tr|G3MXD5-1|G3MXD5_BOVIN Isoform 1 of Kinesin family member 21B OS=Bos taurus OX=9913 GN=KIF21B PE=3 SV=3 CANONICAL=G3MXD5-1" }, "locus": { "chromosome": "16", "start_pos": 79591021, "end_pos": 79549158, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063330.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063330.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054200.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054200.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "", "database": "GlyGen", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "G3MXD5", "url": "https://www.uniprot.org/uniprotkb/G3MXD5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MXD5", "url": "https://www.uniprot.org/uniprotkb/G3MXD5" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "G3MXD5", "url": "https://www.uniprot.org/uniprotkb/G3MXD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "G3MXD5", "url": "https://www.uniprot.org/uniprotkb/G3MXD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJ53-1", "url": "https://www.uniprot.org/uniprotkb/F6RJ53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLINFSCPSLFLGTLAPRPRSAASRGGRRRRAAGTGALEAGAAGTRARARWPGLPLRGAVAREGGGGAVVRRSAGPWVCPAARPRPAPRGGSAPWPATAAAAGGGLGAAGAADREEEGGGAGPWGTEPTAAAGARNPAGAGAAPPAEPRALGERGALAAPSSGPRDSRPGPTRGAPSAAPRSPPRTRPAAGCPGPLGGPAAACGMSRLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSARGPSRALHPAASSSTNCSRPNATAPSSGLPEAPSARPGPTAPVLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLLGGRYTPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPILRRQRLRYGIYVINQHGEDTFNRAKLLNVGFLEALKEDSTYNCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLNKSQFLRINGFPNEYWGWGGEDDDIFNRISLAGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG", "length": 574, "header": "tr|F6RJ53-1|F6RJ53_BOVIN Isoform 1 of Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase OS=Bos taurus OX=9913 GN=B4GALT2 PE=3 SV=2 CANONICAL=F6RJ53-1" }, "isoforms": [ { 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Peptide", "id": "ENSBTAP00000070590.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070590.2" } ] } }, { "isoform_ac": "F6RJ53-1", "url": "https://www.uniprot.org/uniprotkb/F6RJ53/entry", "sequence": { "sequence": "MSLINFSCPSLFLGTLAPRPRSAASRGGRRRRAAGTGALEAGAAGTRARARWPGLPLRGAVAREGGGGAVVRRSAGPWVCPAARPRPAPRGGSAPWPATAAAAGGGLGAAGAADREEEGGGAGPWGTEPTAAAGARNPAGAGAAPPAEPRALGERGALAAPSSGPRDSRPGPTRGAPSAAPRSPPRTRPAAGCPGPLGGPAAACGMSRLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSARGPSRALHPAASSSTNCSRPNATAPSSGLPEAPSARPGPTAPVLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLLGGRYTPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPILRRQRLRYGIYVINQHGEDTFNRAKLLNVGFLEALKEDSTYNCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLNKSQFLRINGFPNEYWGWGGEDDDIFNRISLAGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG", "length": 574, "header": "tr|F6RJ53-1|F6RJ53_BOVIN Isoform 1 of Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase OS=Bos taurus OX=9913 GN=B4GALT2 PE=3 SV=2 CANONICAL=F6RJ53-1" }, "locus": { "chromosome": "3", "start_pos": 102079959, "end_pos": 102070251, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015761.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015761.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015761.7", "url": "https://www.ensembl.org/id/ENSBTAP00000015761.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 342, "start_aa": "Thr", "end_pos": 342, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr342", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" }, { "name": "beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity", "id": "GO:0003831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003831", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" }, { "name": "N-acetyllactosamine synthase activity", "id": "GO:0003945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003945", "evidence": [ { "database": "UniProtKB", "id": "F6RJ53", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17745", "name": "", "equation": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5EA87-1", "P08037-1", "A0A3Q1MBQ6-1", "F6RJ53-1", "F6RH18-1" ], "evidence": [ { "id": "17745", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17745" } ] }, { "id": "22932", "name": "", "equation": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5EA87-1", "P08037-1", "A0A3Q1MBQ6-1", "F6RJ53-1", "F6RH18-1" ], "evidence": [ { "id": "22932", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22932" } ] }, { "id": "62548", "name": "", "equation": "a neolactoside IV(3)-beta-GlcNAc-nLc4Cer + UDP-alpha-D-galactose = a neolactoside nLc6Cer + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5EA87-1", "P08037-1", "A0A3Q1MBQ6-1", "F6RJ53-1", "F6RH18-1" ], "evidence": [ { "id": "62548", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62548" } ] }, { "id": "62552", "name": "", "equation": "a beta-D-glucosylceramide + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5EA87-1", "P08037-1", "A0A3Q1MBQ6-1", "F6RJ53-1", "F6RH18-1" ], "evidence": [ { "id": "62552", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62552" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MBQ6", "gene_name": "B4GALT3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A3Q1MBQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBQ6" } ] } ] }, { "uniprot_ac": "F6RH18", "gene_name": "B4GALT4", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6RH18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RH18" } ] } ] }, { "uniprot_ac": "F6RJ53", "gene_name": "B4GALT2", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F6RJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ] }, { "ec_number": "2.4.1.38", "activity": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "F6RJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ] }, { "ec_number": "2.4.1.90", "activity": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "F6RJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ] }, { "ec_number": "2.4.1.90", "activity": "", "evidence": [ { "id": "F6RJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ] }, { "ec_number": "2.4.1.38", "activity": "", "evidence": [ { "id": "F6RJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" } ] } ] }, { "uniprot_ac": "P08037", "gene_name": "B4GALT1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "P08037", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08037" } ] }, { "ec_number": "2.4.1.275", "activity": "a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + UDP + H(+).", "evidence": [ { "id": "P08037", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08037" } ] }, { "ec_number": "2.4.1.22", "activity": "D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+).", "evidence": [ { "id": "P08037", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08037" } ] }, { "ec_number": "2.4.1.38", "activity": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "P08037", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08037" } ] }, { "ec_number": "2.4.1.90", "activity": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "P08037", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08037" } ] } ] }, { "uniprot_ac": "Q5EA87", "gene_name": "B4GALT3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "Q5EA87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA87" } ] }, { "ec_number": "2.4.1.275", "activity": "a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + UDP + H(+).", "evidence": [ { "id": "Q5EA87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA87" } ] }, { "ec_number": "2.4.1.38", "activity": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "Q5EA87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA87" } ] }, { "ec_number": "2.4.1.90", "activity": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "Q5EA87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA87" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RJ53-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 574, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RJ53-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RJ53" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" }, { "id": "PF02709", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02709" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Galactosyltransferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 437, "end_pos": 514, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ53" }, { "id": "PF13733", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13733" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Galactosyltransferase N-terminal", "eco_id": "ECO_0000259", "start_pos": 299, "end_pos": 432, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00025HU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00025YC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00027JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00030HB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00034UM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00069YC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00079IK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00085FR", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00091UN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00104PH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00112IO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00113FP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00123NG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00152UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00155YT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00164QP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00175UH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00186OS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00196CO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00201AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00210ZX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00212RH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00231WL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00241VQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00247PL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00287UD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00288RP", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00301IL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00321UH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00330GX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00349CA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00368HM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00369RM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00376RB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00383NC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00383YF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00394CR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00396IE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00413UF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00418DG", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G00420CS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00428HK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00430ZK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00432WV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00438EF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00451UT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00464AQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00468NI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00471UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00480KJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00480NH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00496OX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00503EE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00504PZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00514XC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00519UD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00520NI", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00531ZU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00536FZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00545NQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00560KG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00584LL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00591PZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00598SQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00606LX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00624KQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00646SN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00647HI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00653TI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00662IB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00662UH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00666EC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00669WU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00691NS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00706AL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00706VT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00706YM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00707RC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00727QV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00728SN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00729SA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00738BQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00745CN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00745XU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00748RT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00789VI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00797ZX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00805TZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00810PC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00817BI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00826SV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00828CZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00830CM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00835TJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00842OY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00883DO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00884ZO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00886GB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00891GP", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00897BY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00901NZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00908JO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00909PI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00910RZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00910WD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00923KH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00924FH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00932UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00944OL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00948WV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00955WX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00966RI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00967VH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00970XH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00978GW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00978TF", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00979HB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00979XR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00980BE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00986YT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00995HW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00998NI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01001RL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01023RC", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G01034MJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01044XE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01050GH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01056RH", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01069AK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01079TS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01092NQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01116MS", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01120GS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01123UL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01163CA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01169EW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01178HS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01186OB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01218JA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01223AA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01223IC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01233YR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01239JD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01243KR", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01244DB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01260KO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01265XZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01275YS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01284WP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01295AX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01300OI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01304ZB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01308XT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01310VF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01315TQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01323LL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01325OU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01342FO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01354KL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01357LV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01359JE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01361CV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01375NQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01378OV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01385UC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01406RR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01416SG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01422KB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01437WY", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01450RG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01450VD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01454UB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01457KB", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01471GI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01476WA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01489UZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01510MQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01512NR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01521YU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01532FF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01543ZX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01546PE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01553JA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01571OF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01578LK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01582PV", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G01584VI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01587DQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01597IE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01613KN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01616CL", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G01631SU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01643LM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01657DW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01665LU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01666SB", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01668VR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01669LU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01670UQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01674EC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01674VT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01682LD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01701XV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01727PW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01733NS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01734XU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01744JD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G01747FB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01749YL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01750CE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01758EA", "type": "O-linked", "subtype": "O-fucose core, other" }, { "glytoucan_ac": "G01759NM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01772UL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01789AQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01803DO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01818TY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01827FA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01851EU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G01856RL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G01863JX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01879FC", "type": "O-linked", 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"N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01978EJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01996OW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02018EI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02025MF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02032MW", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G02038EU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02041MX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G02057LB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02076VP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G02078ZZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G02081QK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G02106OV", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"subtype": "Tetraantennary" }, { "glytoucan_ac": "G03484HH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03494YC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03505EQ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G03510LN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03520RT", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G03524ZB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G03529DJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G03542LT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G03549GG", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G03554XO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03574EH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G03583SA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03591CN", "type": 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"G11457RF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G11466IA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G11477VF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11479AN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11482NO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G11508EH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G11509RN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G11530HI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G11535IB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G11540FP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G11541AS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11542JY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G11543SV", "type": "N-linked", "subtype": "Tetraantennary" 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"Tetraantennary" }, { "glytoucan_ac": "G11696PX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11700UP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G11704PO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G11721NX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G11734TD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G11745XZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G11762BM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G11800WA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11805NJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G11807HH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G11815LC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11818HY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G11819NV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G11823ZO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G11827HH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G11848VF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G11905ZJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G11924FH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G11927IQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11929CD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G11929SN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G11936KZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G11942BB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G11948QD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G11983UH", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G11986EX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12020PN", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G12032IY", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G12074QJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G12086GM", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G12111NA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12114XT", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G12121CY", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G12122TT", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G12133DL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12133SZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12146BU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12147NL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G12164FF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12174RN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12186NF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12188JQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12201VG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G12203WB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12222NC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12230UX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12232OT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12236OO", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G12241WD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12243WN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12252PH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12254MW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12259JN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12266SO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G12305BJ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G12318EJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12340JM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G12350CH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12352RJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12360RT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12365RQ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G12396GB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12398HZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12405JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G12425WW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12426VA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12436UO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12438DW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G12448WG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12455XO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G12472CC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12474XI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12479WC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12483SU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12486YB", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G12525VG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G12526XX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12531EE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12545NN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12555FT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12561VS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G12573WR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12574EB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G12585IA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G12594VB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12604MY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12614YL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G12616PJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G12631FF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G12637ID", "type": "O-linked", "subtype": "Core 3" }, { 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"G13213HD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G13215FW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G13235YD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G13249MW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G13257IK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G13258AZ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G13260JU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G13267ZY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G13282WA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G13284GZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G13291XJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G13292XY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G13315PT", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"G17856XT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G17857ZF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G17882EL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G17883IE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G17909DH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G17921VC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G17927PV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G17931GP", "type": "O-linked", "subtype": "O-fucose core 2" }, { "glytoucan_ac": "G17940HM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G17964DY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G17964XN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G17968CJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G17969PJ", "type": "N-linked", "subtype": 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"type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G18125MC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G18129IO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G18132YR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G18144ZF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G18149MR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G18157KC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G18160VJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G18165XJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G18196JE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G18197AJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G18205TQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G18209VA", "type": "N-linked", "subtype": "Triantennary" }, { 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"N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19537YP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G19541IU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G19549OP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G19555CW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G19559QA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19565UD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G19572NG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19607EP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G19615BB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G19616IY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G19618VN", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G19626TP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19636RY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G19664QJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G19668FQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G19677BZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19679RY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G19687OL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G19697JA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19697PM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19726AG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19756XC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G19759SI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G19778AE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G19784PB", "type": "N-linked", "subtype": "Tetraantennary" 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"G21312EA", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G21319HP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21327MO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21343HW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21346ZS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21359NQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21361AZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21380FF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21385AQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21412CQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G21420QH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21421NG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21437MZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21438LK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21445UU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G21451CA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21454AE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21459ST", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21470TX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21473QQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21498SM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21513QX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21550DG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21557NG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G21564HN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21609FV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21642VS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21663DV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21679ID", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21696DT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21727SR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21729HC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21733CM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21737WY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21740EF", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G21751SS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21754WR", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G21755KD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21756MV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21760UP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21767ND", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21788RU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21793RV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21807KQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G21825UH", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G21827YQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21828OD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21838QU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21845NG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21850BQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21867ZO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21880FP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21898KP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21901DC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21905ZO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21916IS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21925JZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G21927IY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21929YV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21933XG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21934ZS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G21939VU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21939WK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G21946EN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21967UB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21969LH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21969UD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21969ZB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G21971UP", "type": "O-linked", "subtype": "O-fucose core, other" }, { "glytoucan_ac": "G21986MJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G21989SY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22009DO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22011DS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22012EW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G22014NH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22015SR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22018CH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22022NY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22032KD", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G22043HZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22070LE", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G22083UZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22098NU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22104XU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22107KA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22117HL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22120QI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22137KZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22146SF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22152RD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22161YQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22170TU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22171KQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G22188XM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22204JI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G22222NZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22230QR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22237ZE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22252FR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22264FR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22306HH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G22327AZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22343QB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22354SF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22361XJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22375QZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22385OT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G22388FD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22426TD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22427ZK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22430RE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22437MC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22442GQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22444UV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22447QF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22457TG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22469AE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22486LT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22498IQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22511DQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22511JU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22525ER", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G22533WA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22538PK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22540KI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22558JP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22562AT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22576RV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22587DK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22599MH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22609VV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22611UR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22626SX", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G22629JM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G22668GN", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G22674CI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22678XU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G22686TA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22699IF", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G22728HO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22731HP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22732WO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22733YM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G22754FQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22773YW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22782LH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22787UZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22793FR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22795QB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22803YZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G22815DC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22836DF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22841DM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22849VW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22859OA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22864HF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22864KB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22865RK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22868PF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22887EQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22889SE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22893QE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G22898PA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22912TT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22920IO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22927MQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G22928ZH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22938IP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22946YB", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G22948UY", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G22949KX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G22970UG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G22976NF", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G22979QH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23002WE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G23013VP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23016AG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23021IW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23021NE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G23023HU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G23024PQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23026QZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23048PE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23060KN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23066SI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23072OZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23113ER", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23119MJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23126IF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23134ZR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23142ED", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23142MQ", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G23142YD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23151RC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23162TR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23166NU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23193CN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23200LD", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G23210FC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23237YU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23250OE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G23259KO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23262BU", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G23262LC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23290TL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G23295TF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23296IL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23305TF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23307DT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23314QX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G23330SI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G23340ZN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G23343YD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23345GE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23348CE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23377WN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23378YH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23392LW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G23394RR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23402XL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23404PC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23416CI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23416ZA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23424YW", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G23425OX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G23436FC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23437PF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23438NR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G23451HI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G23456BB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23458QH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23463KX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23484GM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23491CM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G23501RV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G23502AY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G23504NK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G23512SE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23546HG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G23546LY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G23561IL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23562WJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23564VW", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G23577TY", "type": "N-linked", "subtype": 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"subtype": "Tetraantennary" }, { "glytoucan_ac": "G30901GC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G30906WG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G30917DM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G30925FN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G30945GT", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G30966AS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G30968MT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31010RQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31013GB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31019WF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31032XG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31037WG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31040SL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31042LK", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G31051WW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31068OW", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G31073HZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G31087MR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G31101EW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G31106FU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31112DL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31118TG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G31145ZM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31146PE", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G31156QG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31186LT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31198XA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31207MF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31213GU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G31219GT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31246GN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31252KI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31254TP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31276XF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31317BJ", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G31323JQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G31329VE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31333ML", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31337GK", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G31341PC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31345CV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G31365TH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31373ZL", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G31377ER", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G31378RD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G31380TD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31384GR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31406KQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31415DK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31421EZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31456BO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31493NN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G31494OZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31495XA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31515BE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31531YC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31532GK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31540AF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31540HC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G31555TF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31559RO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31563MH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G31577VK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31579YP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31587OK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31601BZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31606TH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31627MW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31637BB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31638QT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31639NG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31661TZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31662BR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31668AP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31670BC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31679YU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31680LJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31692TJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31700GV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31720WP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31721AZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31729QS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G31773DR", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G31787HV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31800YJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31814JO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G31822CM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31828QS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31833FK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31834GI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31849TV", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G31851ZE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31865AG", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G31884XL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G31894KJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G31898CI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31948FR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G31976RQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31979RM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31984FM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31991IV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31993QW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G32065BG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32065KX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32079YD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32088SL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32111TP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32114CQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32116UD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32146HD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32156DB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32173NW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32179HL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32201IL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32211XJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32212NQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32216CL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32216IU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32216KM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32218WF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G32241HI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32243ET", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32247GO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32253LY", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G32272QV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32287FD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32287KU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32289FM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32303MT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32305RZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32324QA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32332OM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32340YV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32342EK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32358YV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32364DF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32364PV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32371XG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32377GZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32378BV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32386AG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32387AH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32395UL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32403EK", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G32405GG", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G32417DU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G32418LI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32429DG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32442UP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32452EX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32460TA", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G32461GF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32483HZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32485KG", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G32489DL", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G32505QR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32510IZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32514NN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32518YQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32522KP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32525PS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32532CU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32551IQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32556JI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G32559WU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32573BX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32590UP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32592IB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32615ZF", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G32624RQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32646BW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32652KI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32659RY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32684NS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G32704TW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32711TF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32722PR", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G32723SL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G32735YJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32746QI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32747GU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32758HZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32761XQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32783AY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32785BQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G32799YM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32808NL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32820BV", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G32829EU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32853SP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32854GF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32854OK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32860NT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32863IR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32877EI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32910OR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32915BP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32944VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G32963JH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32974DS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32981ZX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32998WQ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G33001NX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33012HL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G33018IJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33019PZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33021LP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G33052SB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33057LH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33070ZL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G33082JZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33101CG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G33109AQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33115WA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33135KB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33150PJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33159AG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G33159JX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33187XF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33202XC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33205DY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33225NX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33226VI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33236UO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G33241WC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33244HE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33249QQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33262YZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33269XL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33278DK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33294DV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G33305GI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33309GL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33318UZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33320JS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33328ND", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33334QS", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G33345BX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33364OS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G33370EK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33401IN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33403VX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G33405HJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33417MP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33427JX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33433QA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33438CM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33443GF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33452ME", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33460HH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33474HO", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G33479HZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33487SK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33508VK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33528AU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33567FI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33569OU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33589SN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33593EQ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G33608TH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33610ZO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G33612TW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33620BP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33633KK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33652MJ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G33685ZQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33704KG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33704YC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33718UW", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G33719VU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33728SY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33733QM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33734YD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33739DC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33740YL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G33753EI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33755SK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33758XE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33765AL", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G33769VO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33772BZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G33788DD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33797QF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33802UM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G33806LP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33811WU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G33817OX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33825CM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G33833VC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33841EB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33842PB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33854YU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G33858ZT", "type": "Other", "subtype": "Other" }, { 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"G33981FE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G33986KK", "type": "O-linked", "subtype": "O-mannose core M1" }, { "glytoucan_ac": "G33991ME", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34018EC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34029JA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34039PA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34049BA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G34059TG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34073UX", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G34080GN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34082PC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34096TA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G34100DU", "type": "O-linked", "subtype": "Core 2" 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"subtype": "Triantennary" }, { "glytoucan_ac": "G34291TF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34317IP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34330HT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34336BJ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G34343FT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34392KZ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G34392XW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34424TR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34430BH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34457IL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34477EW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34495UB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34508UC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34513HE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34529TA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34561BL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34582DB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34585DT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34595KJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34603JX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34611ON", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34612DX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34621DB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34626UE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34669ZJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34678QT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34702PI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34706DW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G34718WT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34722LM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34725PD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34731QC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34738CW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34748WY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34754UR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34764BK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G34764WO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34768FN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34784SE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34805BS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34819LS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34820HQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34822AT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34841CD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34851VW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34854XJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G34859KW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34863TS", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G34872AM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34918NO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G34931KK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34946TH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34947FX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34962LY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G34964CV", "type": "O-linked", "subtype": "O-fucose core, other" }, { "glytoucan_ac": "G34972BB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34982PS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34983YN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34985DS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34988BO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34988TR", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G35036QD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G35039VA", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G35067BF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35069CO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35087KV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35106OM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G35109CW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35111DP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35139NO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35194OT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G35199BM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35206AM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35211AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35226HQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35234CM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35242IF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G35243PQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35247XK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G35252UG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G35283JZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35300PC", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G35307UC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G35313CG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35316IV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35338HV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G35347OW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35347WX", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G35367DM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35382VN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G35402TO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35409SK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35419IZ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G35432EX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35438GZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35451HW", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G35452GG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35455OM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G35455VF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35472TK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35481RN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G35482LB", "type": 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"G36861QC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G36868UY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G36909MR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G36935OT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G36937VX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36958OJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G36960FP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G36961BD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G36977EW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36983SB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G36991PL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37003XY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37022BP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37022IM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37043BS", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G37046CZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37070WM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37074DM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G37077JS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37079ZM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37115PC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37134CP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37166HP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G37183DT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37210VL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37223NF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G37231JH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G37239FO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37241GG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37260FV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37271FP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37275PY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37282LW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37291PT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G37304XT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37306TB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37316YK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37318XK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37330EE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37340DV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37354FL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37359EL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37381UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37383BH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37385TT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37416IR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37435GT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37440UJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37467TQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G37487GB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37488LQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37491LV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37492BZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37552GO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37562WX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37581LU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G37591JC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G37597FW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37597VQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37601IJ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G37601UJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37626KE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37626ZT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37638KH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37642WS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37649DI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37653KL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37655HY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G37660EA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37669IH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37673LG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37682CJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37689ZA", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G37716XX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37718JO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37745NY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37772CO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37779JP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37780QM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37783EW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37801HD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37812PU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37825LG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37827FY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G37841WI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37843CX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37861OJ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G37863SX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37868JH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37884CG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37885IZ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G37927WZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G37938RD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37944VQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G37986HU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37990ZT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38001FQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38002BK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38002QN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38004LX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38022PE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38027UF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38032QG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38037QN", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G38057EZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38072IQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38085YD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38115KZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38117WE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38120GJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G38121TQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38141KL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38154PN", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G38189CI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G38208CY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38217AM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38217CX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38230YO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38234JH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38235ZC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38241TC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38249IZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38266ZQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38267IW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38271CW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38277AO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38278VW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38288NX", "type": "O-linked", "subtype": "O-mannose core M1" }, { "glytoucan_ac": "G38291RB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38296RM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38316MW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38322BG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38361SH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38362AS", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G38395YJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38402DW", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G38404PP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38407OC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38418FR", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G38420NQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38453JX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38462TG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38465NT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38468XG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38482UV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38497GA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38498HY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G38540OQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38549YL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38568EL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38579XX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38586WN", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G38613YU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38637SA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38655UZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38658JL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38659HF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38663XJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38667ZB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38674DP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38684VZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G38702PM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38702RY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G38722VX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38728JS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38748VM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38753OV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38767OS", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G38800CP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38812YS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38835AV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38849GM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38859XU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G38883QO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38887NC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38887TM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38895FE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38901GU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38901WO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38908KI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G38909RH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38919CO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38922KN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38930WU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38948TJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38951VC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38955TH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G38958GL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38979WI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38997JB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39011WZ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G39018CC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39027MU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39029JR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39035OI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39037TZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39052XF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39056PQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39062YR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39075QA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39098FX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39100MY", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G39116LG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39125OY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39130DL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G39132UF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39135DL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39136RY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39149XJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39161HZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39170SV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39181YB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39183DW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39229GR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39246KD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39247UK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G39260NC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39283IB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39292VX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39294YF", "type": "O-linked", "subtype": "O-fucose core 2" }, { "glytoucan_ac": "G39296OW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39299DH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39302PS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39305NP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39308RS", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39321UZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39326PP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39340CD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39355VF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39361OH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39370XG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39375NU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39379ZG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39407NE", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G39408YK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39414NM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39417RW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G39421JD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39423SD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39444QC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39452ZZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39461VJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39465KG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39473HX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39482QN", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G39487ZR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39504IG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39509DP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39515DI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39516UK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39523KI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39531LA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39534CW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G39540XG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39546BN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39549VW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39557EZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39565DV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39567LQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39595CR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39597XQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39600NF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39601JQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39602UU", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G39615UL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39624YQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39633IV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39643KO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39645AX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39661KT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39676NA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39686UR", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G39691JY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39716GO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39720OK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39722LF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39735TI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39750GC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39756ZC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39758CF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39758MG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39761CO", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G39762RW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39764AC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39765RY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39783GG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39785OI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39799BM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39800KX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39809FW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39809LE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39812HV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39813YP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39824OQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39829HV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G39868EL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39873VR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39887ME", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39890DX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39893KL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39893XZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39906AT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G39970RY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39977UQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39992DR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39993XV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40027VO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40064GR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40065EM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40067QO", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G40069AV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40079RD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40088CY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40107NH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40125HA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40128VT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40138ED", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40173NY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40173RG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40173TB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40181EN", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G40182HE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40188OO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G40194MN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40200RC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40212MM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40219EV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40221OX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40236GK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40239DI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40264HA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40264QS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40268BC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40270LS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G40289VL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40291QP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G40317YZ", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G40319SF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40341NV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G40343KH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40347YM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40373LS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40384AJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40393FZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40396FX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40397HC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40411HQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40413JC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G40428GO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40429SD", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G40445LE", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G40447LJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40452FK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40455IF", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G40461OS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40463TJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40472QE", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G40475CA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40480ZI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G40482NA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40513EI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40514ET", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G40533LI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40539YV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40542QP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40554DX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40558VT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40560AU", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G40560HO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40560KZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G40565CN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40566IJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40569DS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40578SN", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G40579HH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40606LI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40641DI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40647HS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40650WW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40658KJ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G40660XA", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G40668YU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40670DJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40689UV", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G40704WK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40707RU", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G40707SF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40709XS", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G40728DA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40732RC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40757HO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G40783XQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40785MA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40791GU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40792HV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40796DS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40806JH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G40813TL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40820FX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40825YQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40849ON", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40852TV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40865GN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40903ZD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40905WD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40906DZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40909AN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40909HG", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G40910SH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40922OB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40957MU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40963VD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40966IE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40969DD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40970QY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40979HK", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G40994FC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40998BL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41002DX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G41015SM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41030WJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41036NU", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G41063JS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41068PD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41087ZA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41095QB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41107EH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41112KF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41163WS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41165PK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41171HL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41178OD", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G41191PN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41196CX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41209QO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41224TP", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G41227XH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G41232YR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G41243JF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41245OZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41257VM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41274AJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41286JH", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G41309OX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41321IO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G41322DV", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G41324RH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G41331JX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41352UL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41358UX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41366ZD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41372SJ", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G41384PQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G41387DW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41389FB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41389HP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41403QR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41405AU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G41405QQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41408ND", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41421SQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41451JJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41455NO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41458MM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41458VW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41485LK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41486OC", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G41489AY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41504VL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41511CE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41535JH", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G41539MU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41543HE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41543KR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41543ZO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41552DE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41563EN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41566AJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41575GI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41576FY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41581KJ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G41596PV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41611UG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G41611UP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41655EF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41656NL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41658RK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41659QU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41670EF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41706FJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41711ZZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41726FA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41742IZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41755EF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41780OY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41797KJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41797PU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41800OU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41811VQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41817BL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G41820ZZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41821MR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41823PK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41823TY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41836YE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41847IM", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G41850LO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41850YN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41854MC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41859XD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41865ZJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41878UL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41879EJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G41896LD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G41912CL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41923EO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41928NU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G41934AP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41937ED", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G41953RN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41957CI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G41974MG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G41981MA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G41989TH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42002WQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42011CP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42011NE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42013HP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42022OY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42023VI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42028VS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42039AA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42044GU", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G42058RF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42060JY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42061BV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42077MY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42089IU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42095CU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42097JO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42105TS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42110JE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42120JR", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G42123IU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42133YG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42138LH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G42139GR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42147XQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G42154JB", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G42200QF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42212IP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42239FO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G42239OO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42240DE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42245KI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42264OV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42269YY", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G42295MA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42300CL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42305NI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42316LP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42324WH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42325VD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42332YT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42336ET", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G42358JQ", "type": "N-linked", "subtype": "Alditol-reduced" }, { "glytoucan_ac": "G42362AN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42365AT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42365XA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G42368XT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42380GI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42393CS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42394CB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42400JK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42402VC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42413IW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42415XD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42420NN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42438ZG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42444RF", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G42477ZH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G42482KG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42495TI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42501PR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42501VF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42504VW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42516QP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42530JA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42531AE", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G42600SB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42603RO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42605KJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42612YU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42619IV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42629JY", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G42632OC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42635DR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42640LE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42648OU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42650PV", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G42665KV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42667BL", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G42671TR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42672MA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42674MT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42681RK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42686NP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G42686NQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42713FO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42713IF", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G42713ZO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42714PB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42720OC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42725VI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42731RJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42735RP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42746CP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42752PT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42769EU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42772WO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42779AL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42793SW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42797TX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42801YB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42814RP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42823LH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42823ZD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42824AQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42825JV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42828SU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42830YF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42846BO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42855XG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42862VU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42866WF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42906YD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42909GK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42912TT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G42924MA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42927HH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42929LX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42941KJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42984GS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42989XH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G42993UG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G42996MA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42998PC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43025II", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G43040IL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43057CV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43059PA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43070PV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43073RP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43075VF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43088UA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43091XE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43095XB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43111EJ", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G43122BL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43131ZX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43136RC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43146HZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43150ZU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43164CL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43167FQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G43216EX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43217GA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G43220WQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43242DB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43255OW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43263OG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43265YA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G43280XO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43290KL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43299SD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43301PF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43325ZI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G43330ED", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43330ZT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43343WJ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G43346IY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43346PX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43346UV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43350KZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43351VW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43366RC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43374FV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43415UJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G43433FA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43447HY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43449ON", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43454VB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43460JV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43499QE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43502GT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43519BI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43521WO", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G43523KB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43526DL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43538QE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43553YK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43558RC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43560SB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43563XU", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G43596KL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43603TQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43616YA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43619YE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43639BV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43645EE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43654PQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43657WC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43660IT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43662XM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43664YB", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G43665PB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43668RJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43677TG", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G43680SH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43685DC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43694RQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43702IX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43722HJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43749GH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43761FR", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G43761IQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43765GZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43767FS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G43787NV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43790PG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43797QQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43821JZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43832DJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43838OY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43839NY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43848AQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G43869EE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43873AE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43873MM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43899VP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43923FO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43933MN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43939PS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43963UH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43972TU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43985JK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43989OI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43990ZC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43991QD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43993DD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G44005DK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44021SN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44027TT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44030BX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44031UD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44043ZX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44066XU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44073EJ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G44085QQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44089VB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44092XR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44121LY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44132BD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44137YR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44152CO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44156OE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44160QJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44167WJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44171LY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44182FH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44183XJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44187XB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44202NB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44207QF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44218FP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G44233ST", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G44236OL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44237IH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44244JM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G44246AC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G44264DI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44274UK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44304NG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44306WZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44324HQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44325XR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44327JQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44328YA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44339HI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44346CQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44361OH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44362OF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44364AR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44364RM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44371LQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44374JT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44383XX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44409MI", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G44411RJ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G44414DH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44414IQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44424DD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44448IF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44451GP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44452MM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44452UN", "type": "O-linked", "subtype": "O-mannose core M1" }, { "glytoucan_ac": "G44463UK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44466VN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44480YA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44489BZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44495BT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44497RI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44500MG", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G44504SC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44504WW", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G44510KF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44515AZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44528IE", "type": "O-linked", "subtype": "O-mannose core M1" }, { "glytoucan_ac": "G44541JO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44543KU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44551BR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44553DW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44568DG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44569PZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44572NU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G44575QZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44575RK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44576MS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44597NW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G44598QA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44617RE", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G44617UT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44623TX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44634YI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44639PM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44639QZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G44647TG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G44656CN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44678XW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44688UB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G44717TO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G44722KG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G44723YJ", "type": "N-linked", 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"G46769UK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G46772BG", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G46785SS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G46799MV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G46822ZY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G46823CW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G46842LV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G46854VN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G46915JA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G46922IB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G46935AJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G46991EQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G46992PB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G46998LN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47000SB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47007PV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47017FT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47023TK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47027YN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47031UJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47043LK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47065QM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47085IG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47086RP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47152AG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G47157SQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47169TB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47171PS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47171PW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47174QJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G47175EF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47178AC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47186PA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47199SM", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G47201SK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G47238FR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47251EO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47252EW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47253OG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47253VG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47257MC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47273WV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47279LF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47280HM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47280ZG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47296XJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47299BP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47302FP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47307MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G47325YJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47351YJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47352UW", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G47384NK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47416GK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G47417PO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47421EN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47427YD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47429IK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G47456CG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47459CP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G47498FQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G47501RA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47510VM", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G47519RD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G47519VR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47520QY", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G47525EV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47531XE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47554EG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47557KS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G47560LW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G47562LV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47596RR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47606XQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47623JF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47635WM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47649ZW", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G47651FM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47669CK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G47679MT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47684RW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47709SA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G47736AN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47741BL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47751KU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47760AX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47763TG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47766VH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47772RH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G47780WU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47782UT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47788QH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47797ZT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47809KW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G47816DI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47822QX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47828IM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47835DG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47839DU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47845XM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G47859DD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47866EC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47870LR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47892HA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47925EV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47925PB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G47927EW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G47936PQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47961DI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47963XB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47973FK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G47975JA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G47982BA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G48020LQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G48025ZQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48029ME", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G48040FY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48056PC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G48064BJ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G48069JX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48103NH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48105QY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48109OV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48115DD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G48123IN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48155JS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48185FI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G48192XR", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G48202AJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48205IY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48265DV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48265KY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G48266EY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G48277OH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48305IM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48329CR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48330KH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48339YN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G48343XG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48355MU", "type": "O-linked", "subtype": "Core 2" }, { 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"subtype": "Triantennary" }, { "glytoucan_ac": "G48713OY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G48714KU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G48714ZW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48727OO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G48732OI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48761VJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G48767NV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48768LA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G48779BH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48785BB", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G48789OQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48791KW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G48802KI", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G48809VN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G48809ZO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48822BJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48823WJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G48851YP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G48879CK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48882DX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G48884SG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G48912FN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48945UO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48954CA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G48969JG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G48975GN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G48979ED", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G48987LP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G48998UF", "type": "O-linked", "subtype": "O-fucose core, other" }, { "glytoucan_ac": "G49003MO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G49003YA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G49013BK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G49020UX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G49032YJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G49035IR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G49049ZZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G49053WC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G49062LU", "type": "N-linked", "subtype": "Complex" }, { 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"subtype": "Triantennary" }, { "glytoucan_ac": "G50808YS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50809LR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50817TZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50821RC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50825VR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50829CY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50837EH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50845UM", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G50869YE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50871KO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50893BA", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G50896EJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50896TP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50901FO", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G50905UI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50915WK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50933UG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50937OW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50959AX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50964YW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50968FP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50976TT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50997KD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51004EY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51005JI", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G51007QO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51018GI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51018LC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51023KG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G51041MW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51050LD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51066TO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51074KT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51086FE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51093RA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51098AA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51103QO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51117HW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G51122PB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51131QP", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G51140AE", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G51168MK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51170KR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51188ML", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51216AJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51229TU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51274LI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51299JY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51316WJ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G51318YG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51324UL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51340HW", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G51343UJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G51347IO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51349BU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51353BD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51367TM", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G51378TN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51384DR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51402XK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51402YN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51411MW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51429SM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51448NK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51461ZF", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G51472TJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51473GI", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G51496DK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51500KY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51508GQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51530ER", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51537NW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51554PH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51557QE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51562OR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51579YE", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G51586BA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51586EE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51590AN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51601UI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51602JA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51613CP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51654CU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51670CS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51677OC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G51678TA", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G51688VK", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G51699UE", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G51714ZS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51722JR", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G51726CK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G51743KG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G51747SV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51766BE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51766KQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51768ZH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51793MY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51799AX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51809TM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51842SQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51850PT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51862BI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G51878LH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51880YN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51883EC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51891DI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51891WI", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G51896IF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51908QJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51911XK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G51921XC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51929IB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51930XP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51941IR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51956RJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51963NX", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G51992CI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51994GS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52021KR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52038JM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52056FF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52071EY", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G52080WL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52092BL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52108KM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52112MC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52118BC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G52120NK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52121AE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52126RR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52153CS", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G52179YJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52210EC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52216BO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52217QW", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G52224MB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52225DV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52231BF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52233KF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52239LM", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G52262VT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52266YB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52273YQ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G52286UI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52303GC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52333AW", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G52333TF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52336LJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52345FK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52354QX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52360PJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52362GH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52363CV", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G52367SW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52376IF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52380IS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52383QH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52393JB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52428MJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52441NC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52447UD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52460GS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52460PC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G52483OL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52497YI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52501SI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52515QC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52522DG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52526MZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52558KX", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G52567OL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52576WH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52593LK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52596KQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52605PN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52608IK", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G52621OJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52627IB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52632FK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52633YA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52639VC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52645LW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52649ZM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52663AD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52667KU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G52671WK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52674YL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52676LZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52677OK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52701UC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52724WY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52737IA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52759XA", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G52770HR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52773YO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52790YS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52793JJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52794ID", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52802XR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52811KI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52823TN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52839BU", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G52880ZN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52886CK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52886RR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52892OT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52902AR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G52916PO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G52928OQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G52932JK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52934AK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52935OC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52956BX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52960IE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G52961JQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52971DE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G52971SZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53000BS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53000RQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53023PP", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G53028BV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53031JB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53034PL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G53054ED", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53064IK", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G53084TQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53093MO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53096UD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53098FA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53118DD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53149XZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53151WW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53156MG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53170RJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53173PI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G53203UH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53206FD", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G53208AY", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G53214SL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53219BI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53219PO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53220ZS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53225BR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53230JC", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"Hybrid" }, { "glytoucan_ac": "G53375JJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53396PX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53396TS", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G53404LB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53435KM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53440PM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G53447VR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53454TA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53466SI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53471VF", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G53472RQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53485VW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53490OS", "type": "Other", "subtype": "Other" }, { 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"subtype": "Triantennary" }, { "glytoucan_ac": "G53667CH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53675DS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53709ZS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53723XK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53728DU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53733BK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53737KR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53738ZH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53752QB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53752TA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53765TP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53768QW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53778MF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53800FZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53800IE", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G53800MQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53802DN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53808AO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53809CJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53809VI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53812BX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53817FJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53818ZZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53827VR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53834TX", "type": "O-linked", "subtype": "Core 1" }, { 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"type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54320CV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54323TO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54324NP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54334WY", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G54335XN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G54338PJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54346KI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54375EU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54380FJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54386YN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54394ER", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G54409FD", "type": "O-linked", "subtype": "Core 2" }, { 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"O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G54716GM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54741SP", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G54760IB", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G54764AV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54765AR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54775DO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54803VF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54842UT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G54893WF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54896JZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G54904QW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54931GY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54934XS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G54938LL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G54945YG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54953LX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54956ME", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54961LR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54970OI", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G54977LV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G55005SM", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G55015QS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55020XV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55025YG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G55027AC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55036RV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55040UL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55041IW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55043JL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55051BJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55065WV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55070AA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55084NR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55104BW", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G55121ZY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55126WZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G55144QZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G55146EO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G55152EE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G55157XP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55159LM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55169KX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55174HS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55182ZL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55184GH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55185WK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55205JW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G55205VX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55224LJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55250XM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55251MD", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G55257JO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55258MY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55259BS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55282VK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55302QK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55314RK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55321QC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G55327VV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55331YF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55342MO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55359NC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55360MM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55360NR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55392VH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55396DW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55396WO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55397SP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55402MT", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G55409AD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55413YQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55414RN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55453II", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55453IK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G55459MJ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G55479DB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55480NU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55487QV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G55492KC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55505BS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55505PJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55507EY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55508HJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55528SE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55567ZW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55600PH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55630OZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55636WA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55638XL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55645TD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55648EG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55653LB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55695AY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55701FR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55715VV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55719AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55728EM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G55742WA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55758XD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55773UK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55781KV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55785MZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55803NG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55805LU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55818EE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55827GK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55828KH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55831IL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G55839GD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55861FV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55864VP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55866KK", "type": "O-linked", "subtype": "Core 9" }, { "glytoucan_ac": "G55867TY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55870EJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55879PV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55880FX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55886TV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55890VR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55897OF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55914FN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55959FD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55961AT", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G55963XZ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G55967EP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55974RB", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G55979JS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55986UN", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G56011JM", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G56033SL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56039JB", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G56062OE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56063TZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56086VE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56095ZZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56098XG", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G56102PZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56111FM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G56134WS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56147VV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56151CA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56175MM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56186MJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G56194FV", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G56200PW", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G56202KK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G56246PC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56259BH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56265BA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56269EA", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G56271ML", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56285KF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G56293JI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G56297BE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56318NV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56326BL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G56327CO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56339QG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56340GX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56341HY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56354PO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56363CH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56376TA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G56381GN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56408DR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56427QU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56427WT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G56443JQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56461GY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56485SI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56492IM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56492JP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56499YQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56505IP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56506GT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G56512DX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56516KW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56529CD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G56546LQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56549DH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56555MU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G56571DA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56575BH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G56577TY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56586OT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56591LC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56616DG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56621NM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56637AG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56637MM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56655CC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56657CK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56657VE", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G56678WD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56691CA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56696EG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56703XH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56724VL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56732CH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G56740AO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56749GV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56770AH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56791SN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56809FB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56809XB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56811RE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56822OW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56825HR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56830SM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56837YQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56840FF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56850HF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56852BX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56856OI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56862WE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56869RQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56891ZN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56894NB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56901SP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56913CG", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G56946CM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G56961QY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G56963QZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56966HC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56970BU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56988MG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57001PH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57007FO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G57007KH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57028QM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57032GX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57036KN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57040DY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57044IA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57046HW", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G57051HS", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G57051OG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57052CH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57065EQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57068ZS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57075KG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57075OH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57081OR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57092OJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57092PW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57097HI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57112FM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57117TO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G57125VL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57130XG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G57144YM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G57147TR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57149GY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57149TQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57158CS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57166CI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57208CK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57220BY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57245TH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57250WI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57262WV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G57276IQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G57277JN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57284YH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57295PS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57296XM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G57302WZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57320FY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57327CC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57329WU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57338PU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57345HS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57368BE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57385MA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57411WE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57422AW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G57425PF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57429KQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57429OV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57453LX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57453XN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57466QX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57471CR", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G57482YT", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G57504TA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57510LQ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G57521CV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57521IA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G57532HE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57539MP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57545VN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57565PX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57565TQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57569CO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57580SM", "type": "N-linked", "subtype": "Alditol-reduced" }, { "glytoucan_ac": "G57586DT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57592QM", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G57598XN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G57601AP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57601XR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57607BW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G57636PP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57647XA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57672ST", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G57677EU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57701HX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57710DC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57729TT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57740WC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57755LH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G57762GE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57772TI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57774MT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57789QC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57803ND", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G57826CO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57835AK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57836JM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57843KJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57850KN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G57863LA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57872KZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57881VN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57923KF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57937LQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57941GW", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G57943ZV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57949TL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57955DP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57960MN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57970NA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57976DO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57993RM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G57997IN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G57999XS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58004KD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58006UM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G58016LU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G58025LK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58029XR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58039UH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58039VY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58106KY", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G58111YY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58117BV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58120SB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58141VU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58143RL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58145JY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58181OH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G58194JW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58198HJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58201OX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58207MU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58213EE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58216EF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58217PP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58219MI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58230FJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58233BW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58236FD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58244GN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58251YC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58254FJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58272ZE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58276QF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58278VO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58293BE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G58315CQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58318ME", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58325KK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G58331OS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58350LJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58370UT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58384AV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58386YP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58402CL", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G58403SV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58404RD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58413WQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G58422UX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58424NI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58428QZ", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G58444TO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58455IE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58473KL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58473ZD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58486ZT", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G58489YE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58489ZK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58501OI", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G58511VX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58516UP", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G58517TJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58547FH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58551VR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58561KE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58570WR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58571IP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58574AT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58576YF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58577QT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58580BP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G58582XO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58585VA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58590MR", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G58599KY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58611PK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58620PN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58630HT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58655LE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58660FK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58667NI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58670TY", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G58683GH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58683UL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58736XQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G58768FH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58780EA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58783PZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58788RE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58793GF", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G58798VN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58807XI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58808TX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58809AD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58811EL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58816JP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58824DO", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G58827HR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G58839SI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58848QS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58852KZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58878NJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58886OG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G58890ZT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G58906EB", "type": "N-linked", "subtype": 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"N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G59858XD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G59875OA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G59877NF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G59897WN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G59910CM", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G59914YS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G59920IB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G59930AW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G59930CH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G59942FB", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G59944EN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G59946SQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": 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"G60105PY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60137DJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60170CX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60186EO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60215UL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60227QI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60230OQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60231EF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60233QP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60234BX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60260IY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60271CD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60274JN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60282OI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G60284TY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G60297HX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60320IS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60330MA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60341PX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60343KO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60358PW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60359JC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60384FO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60390SH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60396VE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60413OP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60419KX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60437DK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60439QY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60452UF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60457MA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60461BM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60468EV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60474DY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60483MG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60485RX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60496TU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60496YL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60512QS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60527VO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60532CM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60534GM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60534NQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60542VK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60558WQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60564DP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60603HJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60604SE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60605VB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60605ZN", "type": "O-linked", "subtype": "O-fucose core 2" }, { "glytoucan_ac": "G60606QD", "type": "O-linked", "subtype": "O-mannose core, other" }, { 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"Core-fucosylated" }, { "glytoucan_ac": "G60731ZH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60734PM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60736DD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60741OC", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G60760VW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60765GV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60782IE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G60799ZL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60811PR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60814ZB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60826VF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60829NM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60833BB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G60844ZM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G60859QN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60860OP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60875XB", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G60878OX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60884FR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60884PS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G60890ZT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G60926SE", "type": "N-linked", "subtype": "Alditol-reduced" }, { "glytoucan_ac": "G60941RE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60947HQ", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G60949GI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G60955ML", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G60955VK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60963AS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G60972PW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G60983SU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61002BJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61008CN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61009EJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G61011QL", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G61023PY", "type": "O-linked", "subtype": "O-mannose core M1" }, { "glytoucan_ac": "G61049GY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61058DG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61071ZB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61086WG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61088TM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61089HL", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G61096LS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61119KT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G61133SM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61153TX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61158LP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61159LY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G61176JH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G61203OK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61209FM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G61216ZY", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G61244WO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61247ZD", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G61250GU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61261HA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61274OD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61291WY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G61293SO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61334IA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61335UM", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G61339UO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G61340RH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61367OF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G61400EK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61431VC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G61434JL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G61443KH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61457CY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61467QZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61501FW", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G61505ZR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61519GA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61530CE", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G61539GW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61542DY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61551YB", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G61575RT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61581BE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61582HZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G61603XR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61608CO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G61614JZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61620LE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61636KP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61676ER", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61684ET", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61688RD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61692RF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61705AR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61706MD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G61707PW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61714PI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G61717JN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61717WJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61718TK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61718WP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61721PG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61724IO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G61730RY", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G61734US", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61780GR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G61792ET", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61794OV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61800QD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61809IS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61819UR", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G61838OT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61842MB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61862EM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61866NY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61874BV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G61878VZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61887VA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G61889LW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G61903HE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G61924UW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G61941WO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61947BH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61956VN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G61958FQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61964QE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61969LM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G61970XW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G61972DW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G61983AR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62001BJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62002KG", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G62012MA", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G62012YS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62014YU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62015ZM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G62018IE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62021HG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62044IM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62046IZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62048AU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62065AQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62070TZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62074BC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62081IR", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G62095WZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62112AO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G62120FH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62132YP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62135TC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62145FH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62146BQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62165LJ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G62189UN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62194QH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G62196IB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62217NB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62221RF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62223BD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62223XV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62232KJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62232OO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62249YK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62254QB", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G62259PP", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G62260EJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62270QG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62271MS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62278MB", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G62306AO", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"Triantennary" }, { "glytoucan_ac": "G62414VY", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G62415QZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62428XG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62433DU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62437ME", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62437NU", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G62446JD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62447TX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62464EH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62469XB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62470WX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62480RR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62489DB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62504BU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62517DC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62519IY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62527ZD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62553AU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62577TV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62595CT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62606MC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62619LG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62626SX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62647PO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62654HS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62684WO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62689JX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62707SF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62710LV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62720NT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62738GM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62741RA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G62746IY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62765JV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G62765SF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62776EK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62779OI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62781GE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62786QX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62798PI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62808KR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62824TL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G62828UD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62836JK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62839YJ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G62846AZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62869IR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62881HL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62883YA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G62896US", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62899XL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62900AI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62945MQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62959NG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62960MX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62968IF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G62973JK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G62989ND", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63019NZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63020PM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63065KG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63065ZE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63066XE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G63075AF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G63078AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63100CN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63100TS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63111RL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63113XI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63125QM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63158IX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63160BM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63166WT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63170HT", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G63185SB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63191JH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": 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"G63404EE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G63413QV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63416WN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G63427CD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G63429EI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63443GA", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G63444WV", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G63452MH", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G63452VT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63469RX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63479XH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63480NF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G63491LI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63496QU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G63498YL", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G63515IC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63517NT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G63539AZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63545GS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63547QM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63561NG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63565GW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G63565MO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G63570GH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G63575JI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63596DU", "type": "N-linked", "subtype": "Complex" }, { 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"Tetraantennary" }, { "glytoucan_ac": "G63748AU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G63754TT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G63782AK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G63787FE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G63787RZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63791WF", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G63794QO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G63796IY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G63797PV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63821SF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G63831UM", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G63838JW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G63845LK", "type": "O-linked", "subtype": 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"G68866GS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G68873AT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G68881YW", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G68887VO", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G68892PJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G68894GU", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G68894XH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G68901IK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G68907ZA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G68937TM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G68946DB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G68950LW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G68951DB", "type": "O-linked", "subtype": "Core 2" }, { 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{ "glytoucan_ac": "G69060LX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69065FL", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G69083KH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69086TY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69089FP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69093SL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69098HL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69103XG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69113LL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69118GP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69118IP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69121YI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69137GO", "type": 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"O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69332JU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69381LS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69411IG", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G69420JU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69427EG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69438ML", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G69443HY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69446VU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G69446XZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69448UU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69461KL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69479HX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69485SE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69500TM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69504LD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69522TW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69575FS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69576GO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69616MR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69622NY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69627IL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69627PQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69631DE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69655CC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69657WR", "type": "N-linked", "subtype": "Core-fucosylated" }, { 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"Complex" }, { "glytoucan_ac": "G69748TK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69752OZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G69754MM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69762CO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69762TP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G69774ND", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69788BR", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G69802ND", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G69808IK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69813CQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69824GC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69876CC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G69883FT", "type": "N-linked", "subtype": "Triantennary" }, { 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"N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G70602JC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G70617CF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70623QI", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G70628DE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G70631UV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G70647PV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G70647ZZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G70652JZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G70684QL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G70695OC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G70708DA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70708LW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G70732DF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70737VI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70743LN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70747LW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G70751HC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70765RP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G70783BY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G70800WO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G70812GK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70819AR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G70830AN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G70848XM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70851FQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G70856RV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70857WY", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G70868QU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G70899FX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G70927FR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G70945OS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G70947EQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G70958LU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71013KY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71025TJ", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G71042XC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G71047AU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71063DT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71089RQ", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G71091AL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71094KR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71094TJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71098ZR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71105IW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71108XZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71118NV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71121NN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71125UE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71133TI", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G71156OO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71174VV", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G71176ZY", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G71185WF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71226JJ", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G71234WE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71255YR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71272JH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71295UC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71298BD", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G71306LD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71309WZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71323UV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71332MU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71333BH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71338QU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G71360BB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71360TM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71362YO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71367OV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71380NP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71397MM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71400IH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71402WV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71405MT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71407IE", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G71409LF", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G71423CR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71426FU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71442FU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71451NN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71457DK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71457WH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71479KG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71494ZG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71496TN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71506JZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71511JI", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G71513XV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71529OW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71530LK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71548WJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71550UL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71568CD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71571YH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71586EH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G71606HZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71608WT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71642WP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71652FK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71658OE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71662HP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71668KZ", "type": "O-linked", "subtype": "O-mannose core M1" }, { "glytoucan_ac": "G71673XZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71679MX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71695GL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71698NY", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G71704AG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71707QJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71713QS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71754ZD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71765ZO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71767XQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71773FH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71782CJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71785HW", "type": "N-linked", 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"subtype": "Tetraantennary" }, { "glytoucan_ac": "G71923IX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71943TB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71944BB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71957GO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71957HT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71958XX", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G71961AV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G71964JP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71969OB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71972AT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G71989CT", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G71999UY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G72043OX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72060AW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72060BE", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G72070EH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G72073LJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72075FO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72083DS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72107SE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72112RK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72121YB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72125QI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G72128LZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72130HX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G72131JM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72138YE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72145TT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72154SP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G72156EQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72171BV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G72175XZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G72221XM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72260GO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G72263DG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G72272ID", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72281FQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72289FX", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": 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"G72356VO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72368JX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G72406BE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G72407FN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G72407WU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72446TS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G72460OS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72462NP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G72475NE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G72484NE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72526DQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G72533FB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72544HW", "type": "N-linked", "subtype": "Triantennary" }, { 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"Triantennary" }, { "glytoucan_ac": "G72926ZL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G72929XF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G72937LG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72952WX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72954XC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G72974NP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72992IV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G73001RP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G73057DA", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G73063NN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G73073LQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G73111YU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G73127NE", "type": 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{ "glytoucan_ac": "G80700YJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G80710QD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80713VB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80715XM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80717KS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80719YH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G80726UW", "type": "O-linked", "subtype": "Core 9" }, { "glytoucan_ac": "G80728XN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G80729WA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G80735WD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80738PE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G80748AR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G80759CD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G80762EP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G80764EX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G80804PR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G80822MI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G80825SQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80848DN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G80861DM", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G80941UI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80943NY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G80951VR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G80952QT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G80960YD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G80962OX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81013HU", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G81041HS", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G81060HV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81070NY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81085EP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81096RM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81112MA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G81114MS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81115FG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G81121OC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81128IY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81153QC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81157IG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81167HN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G81201TR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81213GH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G81230EA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81250HV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81272FZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G81282CC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81284BY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81294AE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81294QU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81294ZY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81295TF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81303NJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G81309GY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81324MV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81326IN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81331ZW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81333SO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81335DJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81347KY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81356WP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81367CM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81380NE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81389EF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81392TU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81397LO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81397TP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81413UE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81422ZI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G81430ON", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81443QG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81456UA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81459MV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81471KU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G81473LO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81497EL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81499XS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81516LH", "type": "O-linked", "subtype": "O-mannose core M1" }, { "glytoucan_ac": "G81528UX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81529JB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81534KB", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G81536GE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81541IU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G81554CS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81561UL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81575FZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81581UV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81591DR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81599LG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81601EB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81604KV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81621ZO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81628EZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G81632WR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G81649FJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81676AR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81680BU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G81711AO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81711SM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81725CS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G81728BG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81734TI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81753IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G81753QM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81773GO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81773XZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81796XK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81804CZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81806PG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81825YE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G81832CY", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G81832XS", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G81852HN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81865HP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81869MY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81873QA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81874XM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81880UQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81896KF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81898FC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G81910BW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G81912AC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81915YU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G81929UP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G81952MV", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G81960EK", "type": "N-linked", "subtype": "Alditol-reduced" }, { "glytoucan_ac": "G82011YF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82019GV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82033VN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82035KS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82036CW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82050MN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82052RE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82057XC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82068QZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82080SP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82081LV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G82083TQ", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G82092PV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82107QK", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G82110HP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82113OO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82126PQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82127HP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82127SW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82130LG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82133EG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82136RX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82140BL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82152YZ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G82175BQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G82190TD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82201IZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82208GO", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G82216QD", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G82221BU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82227EQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82234NO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82251XS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82251ZP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82252QI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82258GN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82261XI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82264VK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82273ZM", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G82285OB", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G82320NZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82333QI", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G82334OE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82341NZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82342GJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82350CE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82358WD", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G82362HL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82365EV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82368PU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82370DV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82371YD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82390HZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82393PY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82409TS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G82410AF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82412EH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82417CI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82420SH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82427FY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82454TQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82458BB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82459SD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82487CR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82489VA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82494AO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82503FV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82507IV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82512PT", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G82549MI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G82557QP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82572FN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82579AX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82579CW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82594YX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82597SX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82621OQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82621TY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82638QD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82639GQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82659LR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82662KL", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G82664ZC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82665EP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82687NY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82693QG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82699NN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G82700SN", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G82724NW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82728DG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82730QA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82753OZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G82761BO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82763XK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82773SI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82779CI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82782PE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82785ZH", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G82790IO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G82801WV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82802AE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82811EP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G82831RJ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G82845MH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G82847HG", "type": "N-linked", "subtype": "Triantennary" }, { 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"N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G86681BW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86681SC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G86681UT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G86685MK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G86696LV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86704FB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86704NE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G86704VD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86713OE", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G86730KO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86731GD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86733FS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86735KP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86736BF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G86750HK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G86753CK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86758IR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86766IO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86770JF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86781KH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86782KC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86782PI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G86788TP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86789PZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86869CZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86870NX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86871XB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G86872YM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G86874HJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G86881ZW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G86904UH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86909SR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86912FM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86912UU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86928SV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86928UZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G86938GJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86942VM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86952JZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G86969ZH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86993RB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G86997OW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87001BM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87007IU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G87009PS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G87018HM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87049YA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87064NW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87073UP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87097TR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87106NZ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G87107PF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87124HX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87136DV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87140NS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87178PF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87202LF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87202LK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87202UX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87214SX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87217OF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87218FV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G87228KQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87244OY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87249CK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G87256FP", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G87260SO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87264NH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87273JO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87293AR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87299HQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87310ZF", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G87313QP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87315JQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87318MX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87323EM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87323WR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87334KQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87349MB", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G87349YT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87362FX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87377IM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87377KZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87406OV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87411OD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87411TE", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G87427GY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87430GQ", "type": "N-linked", "subtype": "Triantennary" }, { 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"Complex" }, { "glytoucan_ac": "G87683NV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G87687NN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87690VK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87692UE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87699TW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87706EO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87714OP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87716HX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87720FL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87743LS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87747JF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87807PF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87808DX", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G87820CA", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G87824CU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G87847UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G87852KL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87854BA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87860OU", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G87888LG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87908HE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G87914MQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87921DA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87935PM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87935YG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G87937HR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G87941OV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G87982XZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G87984PA", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G88002CH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88014YP", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G88027AL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88030NF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88038QS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G88043PD", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88050IP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88068QT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88080MC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88089UV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88094DN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88099FG", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G88122BX", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88122ZQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88125IV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88127MB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88137ZY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G88139CF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88176UG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88188XI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88204LN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88212BS", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G88216WD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G88219FI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88224HM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88227HW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88235NV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88238LO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88242BL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88266ZO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88301QF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88304RN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88309FO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88310CR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88315CV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G88321DT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88346DO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88347ND", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G88362BO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88366SU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88366YR", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G88369LF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88369UK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88370LG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88371QM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88382QE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88416XN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88417ED", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88419IN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G88421PE", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G88426SE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88431RN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88431VL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G88435TS", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G88468EP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88495BI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G88500SX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88508SI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88537BJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88582ZD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88605BA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G88609PK", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G88624YG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88670FJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88678EQ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88687UE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88689KL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88696BY", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88708RX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88711NV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88720DN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88725FA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88734GE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88741AN", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G88749TS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88757PX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88759BF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88779WR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88780VN", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G88784SV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G88786SD", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G88800UV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88807WA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88814KX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G88827CD", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G88828CK", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G88837PJ", "type": 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"N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G88963CA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G88966ZO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G88975RE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G88992QY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G89006RL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89036WC", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G89058HG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G89058LG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G89058RF", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G89091LQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G89109GC", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G89129AU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G89143RS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89144TN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89159EV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89168LM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89177YT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89181JW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89194QY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89202HP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89206JP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89210OT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G89215CC", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G89222FP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G89230YO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G89233QM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G89233TP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89242LQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G89242PW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G89255EP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89261EQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89285HT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89307HV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89323TE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89325VN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89333YV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G89343RJ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G89345GA", "type": "N-linked", "subtype": "Triantennary" }, { 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"Triantennary" }, { "glytoucan_ac": "G89498BT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89532GI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89584RR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89585FG", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G89602QT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89615SV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G89615VR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89632SS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89641ZV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89654YT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89664KV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89701XL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89720ZS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G89722NR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G89736EE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89749WS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89753PC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G89769RM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G89794YL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89798IM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G89799OK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89803GR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89808TP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G89816MU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G89826GE", "type": "N-linked", "subtype": "Triantennary" }, { 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}, { "glytoucan_ac": "G89948KF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89949WN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89950GK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G89970IY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G89982KK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G89990JE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G89993FE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G89996XH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G90017UO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90023TN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90028HY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90033AN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90099GV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90103MR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G90111MD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90125QJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90130AG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90133BE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90135ZJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G90163GT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90172SA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90193GR", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G90197OV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90204HK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90205AB", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G90221FQ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G90223PU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90238QO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90242XR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G90244AZ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G90251SV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G90260XX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90267TS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90290ME", "type": "N-linked", "subtype": "Arm-fucosylated" }, { "glytoucan_ac": "G90295ID", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G90304FZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90305AF", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90334KL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90342RA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90348RI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90350EB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G90356TP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90402OU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G90422HW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90435TI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90436CB", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G90439ZM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G90443WR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90451QF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G90493HB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90496SV", "type": "O-linked", "subtype": "O-mannose core M2" }, { "glytoucan_ac": "G90508ZY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90509QW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90510OM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G90532ZJ", "type": "O-linked", "subtype": "O-mannose core, other" }, { "glytoucan_ac": "G90541XX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90542MP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90564EX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90582WZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90596ME", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90598OC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90601SD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90618SW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90633BY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90648JB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G90651NI", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90669BC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90670ZD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90684PC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G90685OB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90686FD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G90689AW", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G90698PW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90703DJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G90712YJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90719DY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G90719YN", "type": "N-linked", 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"N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G99848OC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99853JR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99866WK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99883ZA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99891PR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99893CA", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G99896CG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99943EE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99954ZJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G99956MJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99980II", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G99981ST", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99987ZQ", "type": "O-linked", "subtype": "Core 2" } ], "enzyme_annotation": [ { "ec_number": "2.4.1.38", "ec_name": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "2.4.1.38", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.38" }, { "id": "2.4.1.38", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.38" } ] }, { "ec_number": "2.4.1.90", "ec_name": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "2.4.1.90", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.90" }, { "id": "2.4.1.90", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.90" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 130, 173, 292, 342 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYZ7-1", "uniprot_ac": "G3MYZ7", "uniprot_id": "G3MYZ7_BOVIN", "mass": { "chemical_mass": 403894.0, "monoisotopic_mass": 403894.0 }, "refseq": { "ac": "XP_059747760", "name": "ubiquitin carboxyl-terminal hydrolase 34 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747760" }, "gene_names": [ { "name": "USP34", "type": "recommended", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ] }, { "name": "USP34", "type": "synonym", "evidence": [ { "id": "XP_059747760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747760" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase 34", "type": "recommended", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7/entry#names_and_taxonomy" } ] }, { "name": "Deubiquitinating enzyme 34", "type": "synonym", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase 34", "type": "synonym", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-specific-processing protease 34", "type": "synonym", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 34 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_059747760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747760" } ] } ], "function": [ { "annotation": "Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MIV0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIV0#function" }, { "database": "UniProtKB", "id": "ARBA00053751", "url": "https://www.uniprot.org/uniprotkb/ARBA00053751#function" }, { "database": "UniProtKB", "id": "F1N0A8", "url": "https://www.uniprot.org/uniprotkb/F1N0A8#function" }, { "database": "UniProtKB", "id": "A0A3Q1MDV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDV7#function" }, { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "USP34", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7", "locus": { "chromosome": "11", "start_pos": 59859970, "end_pos": 60101736, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006027", "url": "https://www.ensembl.org/id/ENSBTAG00000006027" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006027", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006027", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02659", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02659", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534067", "url": "https://www.ncbi.nlm.nih.gov/gene/534067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-201681", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201681", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059747760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747760", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIV0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0A8", "url": "https://www.uniprot.org/uniprotkb/F1N0A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0A8-1", "url": "https://www.uniprot.org/uniprotkb/F1N0A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYZ7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCENCADLVEVLNEISDIEGGDGLQLRKEHTLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPQNIERECNEGSTERQKSIEKKSNSTRICNLTEEESSKNSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNLPIGNKKEEEELRRAAPSPWSPAASPQSSDNSDTHQSGGSDIEMDEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSELQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQGPSERSGTNNGTGKDLVFNTESLPSVDNRIRMLDACSHSEDPEHDISGEMNAAHIAQASQESCITRTGDFLGEAIGNELFNCRQFIGPQHHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQFSSNAVTDINLDNVCKKGNTLLWDIVQDDDAVNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQAVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGGSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLTVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKMAVEDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGLNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPMLKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPQILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSDRKEGFKEVSDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEESGKEYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDASVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLLPTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQGQVFSEANCANLISTLITNLINQYQNLQSDFTNRVEISKASAALNGDLRALALLLSVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPVKRRRVSSDEEHTVDSCISDLKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDTSNIRSQHAEEQSNSGRFEDCKELNDLHCSKGSNLAEEESEFPSTSLSAVLSDLADLRSCDGQALSSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "length": 3547, "header": "tr|G3MYZ7-1|G3MYZ7_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Bos taurus OX=9913 GN=USP34 PE=3 SV=3 CANONICAL=G3MYZ7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MDV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDV7/entry", "sequence": { "sequence": "MCENCADLVEVLNEISDIEGGDGLQLRKEHTLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPQNIERECNEGSTERQKSIEKKSNSTRICNLTEEESSKNSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNLPIGNKKEEEELRRAAPSPWSPAASPQSSDNSDTHQSGGSDIEMDEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSELQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQGPSERSGTNNGTGKDLVFNTESLPSVDNRIRMLDACSHSEDPEHDISGEMNAAHIAQASQESCITRTGDFLGEAIGNELFNCRQFIGPQHHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQFSSNAVTDINLDNVCKKGNTLLWDIVQDDDAVNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQAVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGGSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLTVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKMAVEDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGLNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPMLKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPQILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSDRKEGFKEVSDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEESGKEYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDASVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQGQVFSEANCANLISTLITNLINQYQNLQSDFTNRVEISKASAALNGDLRALALLLSVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPVKRRRVSSDEEHTVDSCISDLKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDTSNIRSQHAEEQSNSGRFEDCKELNDLHCSKGSNLAEEESEFPSTSLSAVLSDLADLRSCDGQALSSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "length": 3464, "header": "tr|A0A3Q1MDV7-1|G3MYZ7_BOVIN Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 34 OS=Bos taurus OX=9913 GN=USP34 PE=3 SV=2 CANONICAL=G3MYZ7-1" }, "locus": { "chromosome": "11", "start_pos": 60100495, "end_pos": 59860974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078346.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078346.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068642.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068642.2" } ] } }, { "isoform_ac": "A0A3Q1MIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIV0/entry", "sequence": { "sequence": "MCENCADLVEVLNEISDIEGGDGLQLRKEHTLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPQNIERECNEGSTERQKSIEKKSNSTRICNLTEEESSKNSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNLPIGNKKGSPAASPQSSDNSDTHQSGGSDIEMDEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSELQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQGPSERSGTNNGTGKDLVFNTESLPSVDNRIRMLDACSHSEDPEHDISGEMNAAHIAQASQESCITRTGDFLGEAIGNELFNCRQFIGPQHHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQFSSNAVTDINLDNVCKKGNTLLWDIVQDDDAVNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQAVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGGSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLTVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKMAVEDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGLNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPMLKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPQILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSDRKEGFKEVSDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEESGKEYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDASVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLLPTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQGQVFSEANCANLISTLITNLINQYQNLQSDFTNRVEISKASAALNGDLRALALLLSVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPVKRRRVSSDEEHTVDSCISDLKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDTSNIRSQHAEEQSNSGRFEDCKELNDLHCSKGSNLAEEESEFPSTSLSAVLSDLADLRSCDGQALSSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "length": 3535, "header": "tr|A0A3Q1MIV0-1|G3MYZ7_BOVIN Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 34 OS=Bos taurus OX=9913 GN=USP34 PE=3 SV=2 CANONICAL=G3MYZ7-1" }, "locus": { "chromosome": "11", "start_pos": 60100495, "end_pos": 59860974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076229.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076229.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069109.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069109.2" } ] } }, { "isoform_ac": "F1N0A8-1", "url": "https://www.uniprot.org/uniprotkb/F1N0A8/entry", "sequence": { "sequence": "MLSLLEDTPAVSDIEGGDGLQLRKEHTLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPQNIERECNEGSTERQKSIEKKSNSTRICNLTEEESSKNSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNLPIGNKKEEEELRRAAPSPWSPAASPQSSDNSDTHQSGGSDIEMDEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSELQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQGPSERSGTNNGTGKDLVFNTESLPSVDNRIRMLDACSHSEDPEHDISGEMNAAHIAQASQESCITRTGDFLGEAIGNELFNCRQFIGPQHHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQFSSNAVTDINLDNVCKKGNTLLWDIVQDDDAVNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQAVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGGSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLTVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKMAVEDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGLNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPMLKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPQILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSDRKEGFKEVSDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEESGKEYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDASVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLLPTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQGQVFSEANCANLISTLITNLINQYQNLQSDFTNRVEISKASAALNGDLRALALLLSVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPVKRRRVSSDEEHTVDSCISDLKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDTSNIRSQHAEEQSNSGRFEDCKELNDLHCSKGSNLAEEESEFPSTSLSAVLSDLADLRSCDGQALSSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "length": 3543, "header": "tr|F1N0A8-1|G3MYZ7_BOVIN Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 34 OS=Bos taurus OX=9913 GN=USP34 PE=3 SV=4 CANONICAL=G3MYZ7-1" }, "locus": { "chromosome": "11", "start_pos": 60101537, "end_pos": 59860974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007921.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007921.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007921.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007921.7" } ] } }, { "isoform_ac": "G3MYZ7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7/entry", "sequence": { "sequence": "MCENCADLVEVLNEISDIEGGDGLQLRKEHTLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCALINLVIAQVQVLRDQLCKHCTTINIDSTWQDESNQAEEPQNIERECNEGSTERQKSIEKKSNSTRICNLTEEESSKNSDPFSLWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISTQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQSAARNMADLMWSTVKEPLDTTLCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVVEHIFGPNLHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSALEPSVHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLNTNLPIGNKKEEEELRRAAPSPWSPAASPQSSDNSDTHQSGGSDIEMDEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEVNSSHASQSAGSPGSELQSEDIADIEALKEEDEDDDHGHNPPKSSCGTDLRNRKLESQAGICLGDSQGPSERSGTNNGTGKDLVFNTESLPSVDNRIRMLDACSHSEDPEHDISGEMNAAHIAQASQESCITRTGDFLGEAIGNELFNCRQFIGPQHHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQFSSNAVTDINLDNVCKKGNTLLWDIVQDDDAVNLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLGNNRSVVISLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVYYIQAVREGRQKHALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSAYDGGSNSELCGMDQFWGIALRAQSGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSSLEQESHSSLTVIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRVVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGEFPGGLMGPVRMISSGHELTTDYDEKALHELGFKDMQMVFVSLGAPRRERKGEGVQLPASCLPPPQKDNIPMLLLLQEPHLTTLFDLLEMLASFKPPSGKMAVEDSESLRCEELHLHAENLSRRVWELLMLLPTCPNMLMAFQNISDEQSNDGLNWKELLKIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQVENSKNSWSCKFVAAGGLQQLLEIFNSGILEPKEQESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGIAESHRKRTWPGKSRKAAGDHAKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVSHYSMWLLVSWAHCCSLVKSSLADSDHLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIRIDDYEEEPMLKPGCKEYFWLLCKLVDNIHIKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLIHNWVMAQHMQSHAPYKWDYWPHEDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPQILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKSDRKEGFKEVSDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEESGKEYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWQLCSCIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDGSDDMDASVEDIGGRSCVTRFVRTLLLIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALVALLVEQSRSERHLTLSQTDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCADCPENIRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFIAQRPDMREEELEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENIKLIGGKSNIRPPRPELNMCLLPTMVETSKGKDDVYDRMLLDYFFSYHQFIHLLCRVAINCEKFTETLVKLSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNCIKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFMTHFLLKVQGQVFSEANCANLISTLITNLINQYQNLQSDFTNRVEISKASAALNGDLRALALLLSVHTPKQLNPALIPTLQELLSKCRTCLQQRNSLQEQEAKERKTKDDEGATPVKRRRVSSDEEHTVDSCISDLKTETREVLTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDTSNIRSQHAEEQSNSGRFEDCKELNDLHCSKGSNLAEEESEFPSTSLSAVLSDLADLRSCDGQALSSQDPEVALSLSCGHSRGLFSHMQQHDILDTLCRTIESTIHVVTRISGKGNQAAS", "length": 3547, "header": "tr|G3MYZ7-1|G3MYZ7_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Bos taurus OX=9913 GN=USP34 PE=3 SV=3 CANONICAL=G3MYZ7-1" }, "locus": { "chromosome": "11", "start_pos": 60100495, "end_pos": 59860974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064054.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064054.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054787.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054787.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-201681", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201681", "resource": "Reactome", "description": "TCF dependent signaling in response to WNT" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ7", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1390, "end_pos": 1392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1414, "end_pos": 1416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1693, "end_pos": 1695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2338, "end_pos": 2340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2885, "end_pos": 2887, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3389, "end_pos": 3391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3410, "end_pos": 3412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 875, "end_pos": 877, "annotation": "n_glycosylation_sequon" }, { "start_pos": 915, "end_pos": 917, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-3640872", "name": "USP34 deubiquitinates AXIN1,AXIN2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1B8R5-1", "G3MYZ7-1", "E1BMY0-1", "Q3T139-1" ], "evidence": [ { "id": "R-BTA-3640872", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3640872" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1B8R5", "gene_name": "TNKS", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "E1B8R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R5" } ] } ] }, { "uniprot_ac": "E1BMY0", "gene_name": "TNKS2", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "E1BMY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMY0" } ] } ] }, { "uniprot_ac": "G3MYZ7", "gene_name": "USP34", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" } ] } ] }, { "uniprot_ac": "Q3T139", "gene_name": "RNF146B", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q3T139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T139" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q3T139", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T139" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ7" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 1895, "end_pos": 2240, "start_aa": "Val", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 1390, "end_pos": 1392 }, { "start_pos": 1414, "end_pos": 1416 }, { "start_pos": 1693, "end_pos": 1695 }, { "start_pos": 2338, "end_pos": 2340 }, { "start_pos": 2885, "end_pos": 2887 }, { "start_pos": 3389, "end_pos": 3391 }, { "start_pos": 3410, "end_pos": 3412 }, { "start_pos": 350, "end_pos": 352 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 594, "end_pos": 596 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 875, "end_pos": 877 }, { "start_pos": 915, "end_pos": 917 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"https://www.ncbi.nlm.nih.gov/protein/XP_024850799" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TLE2", "url": "https://www.uniprot.org/uniprotkb/G5E510", "locus": { "chromosome": "7", "start_pos": 20778005, "end_pos": 20748217, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001153", "url": "https://www.ensembl.org/id/ENSBTAG00000001153" } ] } } ], "crossref": [ { "id": "G5E510", "url": "https://alphafold.ebi.ac.uk/entry/G5E510", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001153", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533595", "url": "https://www.ncbi.nlm.nih.gov/gene/533595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AKDERNH", "url": "https://omabrowser.org/oma/group/AKDERNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10814:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10814:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3769402", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3769402", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4641265", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4641265", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024850799", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850799", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJY1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMB1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSRIYCCHRGASLEGRQRQDPRTRPAWNLDRQAPESWRRASWIGRMYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQLQPLAHHAPAVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVTKEERAGVEAEGSRVERVPSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKAPTCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPQDASTPGPSSVSHLRQLAAKPAPSTDSIALRSPLTLSSPFSTSFSLGSHSVLNGDLSVPSSYVSLHLSPQASGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKMPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSSVELLHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISGNNKYIVTGSGDKKATVYEVVY", "length": 789, "header": "tr|G5E510-1|G5E510_BOVIN Isoform 1 of TLE family member 2, transcriptional corepressor OS=Bos taurus OX=9913 GN=TLE2 PE=3 SV=3 CANONICAL=G5E510-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJY1/entry", "sequence": { "sequence": "MGETEPRWETPGLDRQAPESWRRASWIGRMYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQLQPLAHHAPAVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVTKEERAGVEAEGSRVERVPSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKAPTCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPQDASTPGPSSVSHLRQLAAKPAPSTDSIALRSPLTLSSPFSTSFSLGSHSVLNGDLSVPSSYVSLHLSPQASGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKMPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSSVELLHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISGNNKYIVTGSGDKKATVYEVVY", "length": 772, "header": "tr|A0A3Q1LJY1-1|A0A3Q1LJY1_BOVIN Computationally mapped isoform of TLE family member 2, transcriptional corepressor OS=Bos taurus OX=9913 GN=TLE2 PE=3 SV=2 CANONICAL=G5E510-1" }, "locus": { "chromosome": "7", "start_pos": 20777572, "end_pos": 20752711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079758.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079758.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056887.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056887.2" } ] } }, { "isoform_ac": "A0A3Q1MMB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMB1/entry", "sequence": { "sequence": "MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQQLQPLAHHAPAVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVTKEERAGVEAEGSRVERVPSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYDQPSEPPSPATTPCGKAPTCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPQDASTPGPSSVSHLRQLAAKPAPSTDSIALRSPLTLSSPFSTSFSLGSHSVLNGDLSVPSSYVSLHLSPQASGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKMPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSSVELLHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISGNNKYIVTGSGDKKATVYEVVY", "length": 729, "header": "tr|A0A3Q1MMB1-1|G5E510_BOVIN Computationally mapped isoform of TLE family member 2, transcriptional corepressor OS=Bos taurus OX=9913 GN=TLE2 PE=3 SV=3 CANONICAL=G5E510-1" }, "locus": { "chromosome": "7", "start_pos": 20777572, "end_pos": 20757614, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086441.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086441.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072260.3", "url": "https://www.ensembl.org/id/ENSBTAP00000072260.3" } ] } }, { "isoform_ac": "A0AAA9SGL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGL3/entry", "sequence": { "sequence": "MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQLQPLAHHAPAVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVTKEERAGVEAEGSRVERVPSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKAPTCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPQDASTPGPSSVSHLRQLAAKPAPSTDSIALRSPLTLSSPFSTSFSLGSHSVLNGDLSVPSSYVSLHLSPQASGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKMPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQVPHRVWQKWDTSSRKPASLPLPLRHPDARQDQTPTLCVHLSCP", "length": 675, "header": "tr|A0AAA9SGL3-1|G5E510_BOVIN Computationally mapped isoform of TLE family member 2, transcriptional corepressor OS=Bos taurus OX=9913 GN=TLE2 PE=3 SV=1 CANONICAL=G5E510-1" }, "locus": { "chromosome": "7", "start_pos": 20772518, "end_pos": 20757614, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107217.2", "url": "https://www.ensembl.org/id/ENSBTAT00000107217.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083008.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083008.1" } ] } }, { "isoform_ac": "A0AAA9TER7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TER7/entry", "sequence": { "sequence": "MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQQLQPLAHHAPAVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVTKEERAGVEAEGSRVERVPSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKAPTCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPQDASTPGPSSVSHLRQLAAKPAPSTDSIALRSPLTLSSPFSTSFSLGSHSVLNGDLSVPSSYVSLHLSPQASGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKMPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSSVELLHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISGNNKYIVTGSGDKKATVYEVVY", "length": 729, "header": "tr|A0AAA9TER7-1|G5E510_BOVIN Computationally mapped isoform of TLE family member 2, transcriptional corepressor OS=Bos taurus OX=9913 GN=TLE2 PE=3 SV=1 CANONICAL=G5E510-1" }, "locus": { "chromosome": "7", "start_pos": 20777572, "end_pos": 20757614, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127568.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127568.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095314.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095314.1" } ] } }, { "isoform_ac": "A0AAA9TU29-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU29/entry", "sequence": { "sequence": "TPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQQLQPLAHHAPAVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVTKEERAGVEAEGSRVERVPSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKAPTCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPQDASTPGPSSVSHLRQLAAKPAPSTDSIALRSPLTLSSPFSTSFSLGSHSVLNGDLSVPSSYVSLHLSPQASGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKMPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSSVELLHVRKPEKYQLHLHESCVLSLKFASCVQGVLLRAQL", "length": 685, "header": "tr|A0AAA9TU29-1|G5E510_BOVIN Computationally mapped isoform of TLE family member 2, transcriptional corepressor OS=Bos taurus OX=9913 GN=TLE2 PE=3 SV=1 CANONICAL=G5E510-1" }, "locus": { "chromosome": "7", "start_pos": 20777496, "end_pos": 20757715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135131.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135131.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100053.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100053.1" } ] } }, { "isoform_ac": "G5E510-1", "url": "https://www.uniprot.org/uniprotkb/G5E510/entry", "sequence": { "sequence": "MMSRIYCCHRGASLEGRQRQDPRTRPAWNLDRQAPESWRRASWIGRMYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQLQPLAHHAPAVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVTKEERAGVEAEGSRVERVPSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKAPTCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPQDASTPGPSSVSHLRQLAAKPAPSTDSIALRSPLTLSSPFSTSFSLGSHSVLNGDLSVPSSYVSLHLSPQASGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKMPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSSVELLHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISGNNKYIVTGSGDKKATVYEVVY", "length": 789, "header": "tr|G5E510-1|G5E510_BOVIN Isoform 1 of TLE family member 2, transcriptional corepressor OS=Bos taurus OX=9913 GN=TLE2 PE=3 SV=3 CANONICAL=G5E510-1" }, "locus": { "chromosome": "7", "start_pos": 20777572, "end_pos": 20748274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001534.8", "url": "https://www.ensembl.org/id/ENSBTAT00000001534.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001534.7", "url": "https://www.ensembl.org/id/ENSBTAP00000001534.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 360, "start_aa": "Thr", "end_pos": 360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr360", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-BTA-3769402", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3769402", "resource": "Reactome", "description": "Deactivation of the beta-catenin transactivating complex" }, { "id": "R-BTA-4641265", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4641265", "resource": "Reactome", "description": "Repression of WNT target genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K109-1", "protein_name": "TLE family member 2, transcriptional corepressor", "gene_name": "Tle2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYPQGRHPTPLQSGQPFKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAAPHQCPQGGTSCPHWPRLSPLQYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNNLLGQQNQLQPLSHAPPVPLTPRPAGLVGAGATGLLALSGALAAQAQLVAAVKEDRVGVDTEGSRVDRAASRSSSPSPPESLAEEEHPSSRDSNGKQQRAEDKNMSGPYDSEEDKSDYNLVVDEDQPSEPPSPATTPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDLALNDLSTGTPASGSCGPSPPQDSSTPGPSSASHLCQLATQPAPPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSYVSLHLSPQVSSSVVYGCSPLQMAFESHPHLRGSSISLPSIPGAKPAYSFHVSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGKGCVKVWDVGQPGSKTPVAQLDCLNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPSQDWLAVGMESSHVEVLHVRKPEKYQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY", "length": 767 }, "evidence": [ { "id": "G5E510", "url": "https://omabrowser.org/oma/group/G5E510/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LFK9-1", "protein_name": "TLE family member 2, transcriptional corepressor", "gene_name": "TLE2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAVAKEDRTGVEAEGSRVERALSRSVSPSPPESVVEEERPSGLGGNGKQRAEEKDLSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKAPVCIPARRDLVDSPASLASSLGSPLPRAKELVLNDLPASTPASKSCDSSPPEDASTPGPSSASHLRQLAAKPAPSTDSIALRSPLTLSSPFTTSFSLGSHSALNGDLSVPSSYVSLHLSPQVSGSVVYGRSPMMAFESHPHLRGSSISSSLPTIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISGNNKYIVTGSGDKKATVYEVVY", "length": 743 }, "evidence": [ { "id": "G5E510", "url": "https://omabrowser.org/oma/group/G5E510/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q04725-1", "protein_name": "Transducin-like enhancer protein 2", "gene_name": "TLE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEAEGSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY", "length": 743 }, "evidence": [ { "id": "G5E510", "url": "https://omabrowser.org/oma/group/G5E510/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVB2-1", "protein_name": "Transducin-like enhancer protein 2", "gene_name": "Tle2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYPQGRHPTPLQSGQPFKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAAPHQCPQGGTSYPHWPRLSPLQYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNSLLGQQNQLQPLSHAPPVPLTPRPAGLVGAGATGLLALSGALAAQAQLVAAVKEDRVGVDAEGSRVDRAASRSSSPSPPESLVEEDHPSSRGGSGKQQRAEDKDLSGPYDSEEDKSDYNLVVDEDQPSEPPSPVTTPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRSCGTSPPQDSSTPGPSSASHLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSYVGLHLSPQVSSSVVYGRSPLQMAFESHPHLRGSSVSLPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGKGCVKVWDVGQPGSKTPVAQLDCLNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPEKYQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY", "length": 767 }, "evidence": [ { "id": "G5E510", "url": "https://omabrowser.org/oma/group/G5E510/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "G5E510", "url": "https://www.uniprot.org/uniprotkb/G5E510" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 624, "end_pos": 626, "annotation": 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"sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZ11-1", "uniprot_ac": "G3MZ11", "uniprot_id": "G3MZ11_BOVIN", "mass": { "chemical_mass": 319981.0, "monoisotopic_mass": 319981.0 }, "refseq": { "ac": "XP_002684727", "name": "very large A-kinase anchor protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684727" }, "gene_names": [ { "name": "CRYBG3", "type": "recommended", "evidence": [ { "id": "G3MZ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ] }, { "name": "CRYBG3", "type": "synonym", "evidence": [ { "id": "XP_002684727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684727" } ] } ], "protein_names": [ { "name": "Crystallin beta-gamma domain containing 3", "type": "synonym", "evidence": [ { "id": "G3MZ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ11/entry#names_and_taxonomy" } ] }, { "name": "very large A-kinase anchor protein", "type": "synonym", "evidence": [ { "id": "XP_002684727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684727" } ] } ], "function": [ { "annotation": "Crystallins are the dominant structural components of the vertebrate eye lens.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFN2#function" }, { "database": "UniProtKB", "id": "ARBA00003689", "url": "https://www.uniprot.org/uniprotkb/ARBA00003689#function" }, { "database": "UniProtKB", "id": "F1MTZ5", "url": "https://www.uniprot.org/uniprotkb/F1MTZ5#function" }, { "database": "UniProtKB", "id": "A0AAA9TML3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML3#function" }, { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CRYBG3", "url": "https://www.uniprot.org/uniprotkb/G3MZ11", "locus": { "chromosome": "1", "start_pos": 42197082, "end_pos": 42070435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047147", "url": "https://www.ensembl.org/id/ENSBTAG00000047147" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047147", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047147", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516526", "url": "https://www.ncbi.nlm.nih.gov/gene/516526", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516526", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516526", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEDKPEP", "url": "https://omabrowser.org/oma/group/YEDKPEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFN2", "url": "https://www.orthodb.org/?gene=A0A3Q1LFN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MTZ5", "url": "https://www.orthodb.org/?gene=F1MTZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZ11", "url": "https://www.orthodb.org/?gene=G3MZ11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002684727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002684727", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TML3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TML3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTZ5", "url": "https://www.uniprot.org/uniprotkb/F1MTZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1MTZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ11-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGRRRGGAPWHSFSRFFAPRSPSRDKEEEEEERPGTSQPPAPGRDAASVENEPMSTSQKKENILSSEAVKISQSEDRRTQAQQLITLPTQEDSKKPNDLSSSTSEAKIGESDKQTKESFFQFLGNLFNISGKSSLSEAKQSSFKDEHDKPEKDLRNPSRHEEGGQRESAGGSLRTQALPAEEQSSSAELSDAFSLDTTQDSEQETSDLLKQMDGKSERPLVTYATYRGPRQIKKYLKQQTVSETVNPLDRENASSDSSTSTHRGPGSEMEAGMVLLLSSASTGIPVKGQGPEGQLEDSDDNERDLNTGSHSTNNQGLANTASSRGVLNKAYPGGPETSRSSHSVTSSSSTAGDSDSRHHLSCAPGSQTDRNLGCSALCTESNSSKIPYSPDLERTATPGTVVKRTSSVMSDGTPVQAENSAVADFSCSKSDGSDPTTLRSADLLSPNKSIRREALQLPESKCSNKQAVENSSKQPANHTSSMAFQKQAVTDTELVNAGNRSSAQDTQKNLAPAEIKPETENTSGEEPTASSHVKAPEDRIESLHKDTDLLLLTEVKNLVRPHGKVPPFRMNQKEAASVKHTSESVVVTCLENKIAPELNIELNRNHISESLLDSESPQQAIASPDARTSPSLGHKSDFSASHPTFVSRVGMLSQVDIPILKNEGSSVLVETGDVNIVGISSQPPQCQQEHVANHVEATDRKSLPAGLHSKYAPTALESKEVLPDREKCQFLLDLEASDTDITAVDLSFEPASLSQDPEKAESVLSSTAASESTADKLDSSFSLETKTDSIAEMLPEADIGGQNNVPVESHSETGKTLSLSKIPVTRTEPRDISQDEISSPLDITGVPANPALSELTSLEVEQDKIFQLVDHEEIKEKYLDASLKESCQTEVSPSASKYQGVQGTEVGACRALPACLQSNRPETSPPVHDEKVTRQVAQNCAARASIIHPPSVPCGSKKIFDFSQLSLANTSPKFQETDSTKAKSPFLGSGISLRKEAFASEDSSFLPNPSVLRTEKRASSPRNKEDAHSLRGGTHSLPSSSSNSEVSMVRSSYNPTNNFSSVKVPIDVTHEGASLTNLLDPKSSYLESETSDLTGAEVTPLQDHLGDPTGMVSLDFPTAAQFDNPLEAATGAVAGTPASVNSSSQQCSEASAEHTEARKRAHAQLLDLESDFCKKAVTLIGEAFNSVREELKSKHSVGTCQEHRAIDSIMNPGTLEEDIPEKNPSEVTLTEIQSTEHLEEQAVENIPEVQGEEKACVSPVVGENSLLFNSDKMNVCWLLEDRARELVNQIIYSAQETVANDAQGTSDSELQANTSEILRSDSVQPCDMVREFLVSEQAINQSTCEISGKVLGRFFAESNLGSDTESIRGREIVLYQKSPFSGTRDGQSDSINLQESDTVLLAENIPLTGLDDKAKTHSFLKEDSKEKMGTECVDNHKPETEDTRTLVLNFKWPPFVNDDTHVPGTSKSSLSDTYVCLSEKSLPGHSNKSTSLAMSEVGKIHKDTEVNIGKIELIPSMVEMGKPNKKDAELNIMKYEAVPPMSEVGRAHKEDAELSTSETEPTAEILKMREAYQMDAERYIEKTEGLPATLEMENICQKDAEGDIAKTEVTPVTLEMENIYQKHAEGDVGKTGMTSVVSEMDSIYQKDIEGTAEKPESIPARLEMESIYQKDAEGKVDKTGVMSLTLEVVNVYRKDGEGITAKTEGPLLDLENTYQNGAEGVIRKTEMMPPFVLEMKEAPQKAVPASFEICKGDMKETSRGTLSTPSKREMESTFPEDSDGTIRKHIVFPTAVSSEKIPGTGLELPITQAEATSPIPEAEEAYQEGADRSGGEVEKEPTETKTGWIAGDTRLASYFRDYESPTLSKDNEGHPALAVPDFQPEGTMGRLDRKTSVTTVYKKVRDLQYGDKKEEPNLAFVSQEEQENSSFTILYEEPLQNEDKYTTTEVRRTHSLLIPHTAPNSMPVFACERSESRTDLVHHFEKEAKLGDAFDSDSSETFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGRHGASKSRENASQPSSVLSLLQSVSERLKMNFDEDDRQEGGEEEEEEDEEEPLHKGSLRAQRQETVTFKQPDSSLTFCSDDDRESTGVSKNSYVMSNEPTTSNLQIGLWPEKASFLQKSDLTSKLHSSLKSAYHQYLQTSKTHSSEKGARFGGIFQEPVSKYFRTQDTPGRLSPFTENVDKQTLKCNPRPGKMVIYDLHRRKYKQEIYCNIPDATSWSYPNGVLIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWLLQNRKHPQRNFVLGSIKRVLKDCSIPEIELCPQSDPACCPIYIQRAVPNLEELNIPKSVSFTVKSGVWLAYPDINFKGQAIVLEEDHGLFEISAAEIKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNDVDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNAFGALSGSILSFRYLQANFIESSITLFESDLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNTIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTKEVLDLTSSFMPCSFKVLRGCWLLYYQEGVSTNQCVLEEGLYADLTSCGCPTSRVKSLKPIDYVFEEPSLSLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGPNFLGRQILLEPNEIPNWRAFSGWKTIGSLRPVKQPSVYIRIRNRAQDGYLTVTGNVADTRATSVCISPYSGKNTQIWHYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRLNRNGTISSYLSDQLVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL", "length": 2903, "header": "tr|G3MZ11-1|G3MZ11_BOVIN Isoform 1 of Crystallin beta-gamma domain containing 3 OS=Bos taurus OX=9913 GN=CRYBG3 PE=3 SV=2 CANONICAL=G3MZ11-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFN2/entry", "sequence": { "sequence": "MSTSQKKENILSSEAVKISQSEDRRTQAQQLITLPTQEDSKKPNDLSSSTSEAKIGESDKQTKESFFQFLGNLFNISGKSSLSEAKQSSFKDEHDKPEKDLRNPSRHEEGGQRESAGGSLRTQALPAEEQSSSAELSDAFSLDTTQDSEQETSDLLKQMDGKSERPLVTYATYRGPRQIKKYLKQQTVSETVNPLDRENASSDSSTSTHRGPGSEMEAGMVLLLSSASTGIPVKGQGPEGQLEDSDDNERDLNTGSHSTNNQGLANTASSRGVLNKAYPGGPETSRSSHSVTSSSSTAGDSDSRHHLSCAPGSQTDRNLGCSALCTESNSSKIPYSPDLERTATPGTVVKRTSSVMSDGTPVQAENSAVADFSCSKSDGSDPTTLRSADLLSPNKSIRREALQLPESKCSNKQAVENSSKQPANHTSSMAFQKQAVTDTELVNAGNRSSAQDTQKNLAPAEIKPETENTSGEEPTASSHVKAPEDRIESLHKDTDLLLLTEVKNLVRPHGKVPPFRMNQKEAASVKHTSESVVVTCLENKIAPELNIELNRNHISESLLDSESPQQAIASPDARTSPSLGHKSDFSASHPTFVSRVGMLSQVDIPILKNEGSSVLVETGDVNIVGISSQPPQCQQEHVANHVEATDRKSLPAGLHSKYAPTALESKEVLPDREKCQFLLDLEASDTDITAVDLSFEPASLSQDPEKAESVLSSTAASESTADKLDSSFSLETKTDSIAEMLPEADIGGQNNVPVESHSETGKTLSLSKIPVTRTEPRDISQDEISSPLDITGVPANPALSELTSLEVEQDKIFQLVDHEEIKEKYLDASLKESCQTEVSPSASKYQGVQGTEVGACRALPACLQSNRPETSPPVHDEKVTRQVAQNCAARASIIHPPSVPCGSKKIFDFSQLSLANTSPKFQETDSTKAKSPFLGSGISLRKEAFASEDSSFLPNPSVLRTEKRASSPRNKEDAHSLRGGTHSLPSSSSNSEVSMVRSSYNPTNNFSSVKVPIDVTHEGASLTNLLDPKSSYLESETSDLTGAEVTPLQDHLGDPTGMVSLDFPTAAQFDNPLEAATGAVAGTPASVNSSSQQCSEASAEHTEARKRAHAQLLDLESDFCKKAVTLIGEAFNSVREELKSKHSVGTCQEHRAIDSIMNPGTLEEDIPEKNPSEVTLTEIQSTEHLEEQAVENIPEVQGEEKACVSPVVGENSLLFNSDKMNVCWLLEDRARELVNQIIYSAQETVANDAQGTSDSELQANTSEILRSDSVQPCDMVREFLVSEQAINQSTCEISGKVLGRFFAESNLGSDTESIRGREIVLYQKSPFSGTRDGQSDSINLQESDTVLLAENIPLTGLDDKAKTHSFLKEDSKEKMGTECVDNHKPETEDTRTLVLNFKWPPFVNDDTHVPGTSKSSLSDTYVCLSEKSLPGHSNKSTSLAMSEVGKIHKDTEVNIGKIELIPSMVEMGKPNKKDAELNIMKYEAVPPMSEVGRAHKEDAELSTSETEPTAEILKMREAYQMDAERYIEKTEGLPATLEMENICQKDAEGDIAKTEVTPVTLEMENIYQKHAEGDVGKTGMTSVVSEMDSIYQKDIEGTAEKPESIPARLEMESIYQKDAEGKVDKTGVMSLTLEVVNVYRKDGEGITAKTEGPLLDLENTYQNGAEGVIRKTEMMPPFVLEMKEAPQKAVPASFEICKGDMKETSRGTLSTPSKREMESTFPEDSDGTIRKHIVFPTAVSSEKIPGTGLELPITQAEATSPIPEAEEAYQEGADRSGGEVEKEPTETKTGWIAGDTRLASYFRDYESPTLSKDNEGHPALAVPDFQPEGTMGRLDRKTSVTTVYKKVRDLQYGDKKEEPNLAFVSQEEQENSSFTILYEEPLQNEDKYTTTEVRRTHSLLIPHTAPNSMPVFACERSESRTDLVHHFEKEAKLGDAFDSDSSETFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGRHGASKSRENASQPSSVLSLLQSVSERLKMNFDEDDRQEGGEEEEEEDEEEPLHKGSLRAQRQETVTFKQPDSSLTFCSDDDRESTGVSKNSYVMSNEPTTSNLQIGLWPEKASFLQKSDLTSKLHSSLKSAYHQYLQTSKTHSSEKGARFGGIFQEPVSKYFRTQDTPGRLSPFTENVDKQTLKCNPRPGKMVIYDLHRRKYKQEIYCNIPDATSWSYPNGVLIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWLLQNRKHPQRNFVLGSIKRVLKDCSIPEIELCPQSDPACCPIYIQRAVPNLEELNIPKSVSFTVKSGVWLAYPDINFKGQAIVLEEDHGLFEISAAEIKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNDVDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNAFGALSGSILSFRYLQANFIESSITLFESDLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNTIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTKEVLDLTSSFMPCSFKVLRGCWLLYYQEGVSTNQCVLEEGLYADLTSCGCPTSRVKSLKPIDYVFEEPSLSLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGPNFLGRQILLEPNEIPNWRAFSGWKTIGSLRPVKQPSVYIRIRNRAQDGYLTVTGNVADTRATSVCISPYSGKNTQIWHYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRLNRNGTISSYLSDQLVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL", "length": 2848, "header": "tr|A0A3Q1LFN2-1|G3MZ11_BOVIN Computationally mapped isoform of Crystallin beta-gamma domain containing 3 OS=Bos taurus OX=9913 GN=CRYBG3 PE=3 SV=2 CANONICAL=G3MZ11-1" }, "locus": { "chromosome": "1", "start_pos": 42196078, "end_pos": 42088440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082599.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082599.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057018.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057018.2" } ] } }, { "isoform_ac": "A0AAA9TML3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML3/entry", "sequence": { "sequence": "MSGGRRRGGAPWHSFSRFFAPRSPSRDKEEEEEERPGTSQPPAPGRDAASVENEPMSTSQKKENILSSEAVKISQSEDRRTQAQQLITLPTQEDSKKPNDLSSSTSEAKIGESDKQTKESFFQFLGNLFNISGKSSLSEAKQSSFKDEHDKPEKDLRNPSRHEEGGQRESAGGSLRTQALPAEEQSSSAELSDAFSLDTTQDSEQETSDLLKQMDGKSERPLVTYATYRGPRQIKKYLKQQTVSETVNPLDRENASSDSSTSTHRGPGSEMEAGMVLLLSSASTGIPVKGQGPEGQLEDSDDNERDLNTGSHSTNNQGLANTASSRGVLNKAYPGGPETSRSSHSVTSSSSTAGDSDSRHHLSCAPGSQTDRNLGCSALCTESNSSKIPYSPDLERTATPGTVVKRTSSVMSDGTPVQAENSAVADFSCSKSDGSDPTTLRSADLLSPNKSIRREALQLPESKCSNKQAVENSSKQPANHTSSMAFQKQAVTDTELVNAGNRSSAQDTQKNLAPAEIKPETENTSGEEPTASSHVKAPEDRIESLHKDTDLLLLTEVKNLVRPHGKVPPFRMNQKEAASVKHTSESVVVTCLENKIAPELNIELNRNHISESLLDSESPQQAIASPDARTSPSLGHKSDFSASHPTFVSRVGMLSQVDIPILKNEGSSVLVETGDVNIVGISSQPPQCQQEHVANHVEATDRKSLPAGLHSKYAPTALESKEVLPDREKCQFLLDLEASDTDITAVDLSFEPASLSQDPEKAESVLSSTAASESTADKLDSSFSLETKTDSIAEMLPEADIGGQNNVPVESHSETGKTLSLSKIPVTRTEPRDISQDEISSPLDITGVPANPALSELTSLEVEQDKIFQLVDHEEIKEKYLDASLKESCQTEVSPSASKYQGVQGTEVGACRALPACLQSNRPETSPPVHDEKVTRQVAQNCAARASIIHPPSVPCGSKKIFDFSQLSLANTSPKFQETDSTKAKSPFLGSGISLRKEAFASEDSSFLPNPSVLRTEKRASSPRNKEDAHSLRGGTHSLPSSSSNSEVSMVRSSYNPTNNFSSVKVPIDVTHEGASLTNLLDPKSSYLESETSDLTGAEVTPLQDHLGDPTGMVSLDFPTAAQFDNPLEAATGAVAGTPASVNSSSQQCSEASAEHTEARKRAHAQLLDLESDFCKKAVTLIGEAFNSVREELKSKHSVGTCQEHRAIDSIMNPGTLEEDIPEKNPSEVTLTEIQSTEHLEEQAVENIPEVQGEEKACVSPVVGENSLLFNSDKMNVCWLLEDRARELVNQIIYSAQETVANDAQGTSDSELQANTSEILRSDSVQPCDMVREFLVSEQAINQSTCEISGKVLGRFFAESNLGSDTESIRGREIVLYQKSPFSGTRDGQSDSINLQESDTVLLAENIPLTGLDDKAKTHSFLKEDSKEKMGTECVDNHKPETEDTRTLVLNFKWPPFVNDDTHVPGTSKSSLSDTYVCLSEKSLPGHSNKSTSLAMSEVGKIHKDTEVNIGKIELIPSMVEMGKPNKKDAELNIMKYEAVPPMSEVGRAHKEDAELSTSETEPTAEILKMREAYQMDAERYIEKTEGLPATLEMENICQKDAEGDIAKTEVTPVTLEMENIYQKHAEGDVGKTGMTSVVSEMDSIYQKDIEGTAEKPESIPARLEMESIYQKDAEGKVDKTGVMSLTLEVVNVYRKDGEGITAKTEGPLLDLENTYQNGAEGVIRKTEMMPPFVLEMKEAPQKAVPASFEICKGDMKETSRGTLSTPSKREMESTFPEDSDGTIRKHIVFPTAVSSEKIPGTGLELPITQAEATSPIPEAEEAYQEGADRSGGEVEKEPTETKTGWIAGDTRLASYFRDYESPTLSKDNEGHPALAVPDFQPEGTMGRLDRKTSVTTVYKKVRDLQYGDKKEEPNLAFVSQEEQENSSFTILYEEPLQNEDKYTTTEVRRTHSLLIPHTAPNSMPVFACERSESRTDLVHHFEKEAKLGDAFDSDSSETFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGRHGASKSRENASQPSSVLSLLQSVSERLKMNFDEDDRQEGGEEEEEEDEEEPLHKGSLRAQRQETVTFKQPDSSLTFCSDDDRESTGVSKNSYVMSNEPTTSNLQIGLWPEKASFLQKSDLTSKLHSSLKSAYHQYLQTSKTHSSEKGARFGGIFQEPVSKYFRTQDTPGRLSPFTENVDKQTLKCNPRPGKMVIYDLHRRKYKQEIYCNIPDATSWSYPNGVLIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWLLQNRKHPQRNFVLGSIKRVLKDCSIPEIELCPQSDPACCPIYIQRAVPNLEELNIPKSVSFTVKSGVWLAYPDINFKGQAIVLEEDHGLFEISAAEIKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNDVDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNAFGALSGSILSFRYLQANFIESSITLFESDLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNTIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTKEVLDLTSSFMPCSFKVLRGCWLLYYQEGVSTNQCVLEEGLYADLTSCGCPTSRVKSLKPIDYVFEEPSLSLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGPNFLGRQILLEPNEIPNWRAFSGWKTIGSLRPVKQATALKTSRGILGTYNSTESFVHSVTKPDPA", "length": 2798, "header": "tr|A0AAA9TML3-1|G3MZ11_BOVIN Computationally mapped isoform of Crystallin beta-gamma domain containing 3 OS=Bos taurus OX=9913 GN=CRYBG3 PE=3 SV=1 CANONICAL=G3MZ11-1" }, "locus": { "chromosome": "1", "start_pos": 42190516, "end_pos": 42070652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109938.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109938.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099618.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099618.1" } ] } }, { "isoform_ac": "F1MTZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1MTZ5/entry", "sequence": { "sequence": "MCSAWRLSKPSHDRQMDGKSERPLVTYATYRGPRQIKKYLKQQTVSETVNPLDRENASSDSSTSTHRGPGSEMEAGMVLLLSSASTGIPVKGQGPEGQLEDSDDNERDLNTGSHSTNNQGLANTASSRGVLNKAYPGGPETSRSSHSVTSSSSTAGDSDSRHHLSCAPGSQTDRNLGCSALCTESNSSKIPYSPDLERTATPGTVVKRTSSVMSDGTPVQAENSAVADFSCSKSDGSDPTTLRSADLLSPNKSIRREALQLPESKCSNKQAVENSSKQPANHTSSMAFQKQAVTDTELVNAGNRSSAQDTQKNLAPAEIKPETENTSGEEPTASSHVKAPEDRIESLHKDTDLLLLTEVKNLVRPHGKVPPFRMNQKEAASVKHTSESVVVTCLENKIAPELNIELNRNHISESLLDSESPQQAIASPDARTSPSLGHKSDFSASHPTFVSRVGMLSQVDIPILKNEGSSVLVETGDVNIVGISSQPPQCQQEHVANHVEATDRKSLPAGLHSKYAPTALESKEVLPDREKCQFLLDLEASDTDITAVDLSFEPASLSQDPEKAESVLSSTAASESTADKLDSSFSLETKTDSIAEMLPEADIGGQNNVPVESHSETGKTLSLSKIPVTRTEPRDISQDEISSPLDITGVPANPALSELTSLEVEQDKIFQLVDHEEIKEKYLDASLKESCQTEVSPSASKYQGVQGTEVGACRALPACLQSNRPETSPPVHDEKVTRQVAQNCAARASIIHPPSVPCGSKKIFDFSQLSLANTSPKFQETDSTKAKSPFLGSGISLRKEAFASEDSSFLPNPSVLRTEKRASSPRNKEDAHSLRGGTHSLPSSSSNSEVSMVRSSYNPTNNFSSVKVPIDVTHEGASLTNLLDPKSSYLESETSDLTGAEVTPLQDHLGDPTGMVSLDFPTAAQFDNPLEAATGAVAGTPASVNSSSQQCSEASAEHTEARKRAHAQLLDLESDFCKKAVTLIGEAFNSVREELKSKHSVGTCQEHRAIDSIMNPGTLEEDIPEKNPSEVTLTEIQSTEHLEEQAVENIPEVQGEEKACVSPVVGENSLLFNSDKMNVCWLLEDRARELVNQIIYSAQETVANDAQGTSDSELQANTSEILRSDSVQPCDMVREFLVSEQAINQSTCEISGKVLGRFFAESNLGSDTESIRGREIVLYQKSPFSGTRDGQSDSINLQESDTVLLAENIPLTGLDDKAKTHSFLKEDSKEKMGTECVDNHKPETEDTRTLVLNFKWPPFVNDDTHVPGTSKSSLSDTYVCLSEKSLPGHSNKSTSLAMSEVGKIHKDTEVNIGKIELIPSMVEMGKPNKKDAELNIMKYEAVPPMSEVGRAHKEDAELSTSETEPTAEILKMREAYQMDAERYIEKTEGLPATLEMENICQKDAEGDIAKTEVTPVTLEMENIYQKHAEGDVGKTGMTSVVSEMDSIYQKDIEGTAEKPESIPARLEMESIYQKDAEGKVDKTGVMSLTLEVVNVYRKDGEGITAKTEGPLLDLENTYQNGAEGVIRKTEMMPPFVLEMKEAPQKAVPASFEICKGDMKETSRGTLSTPSKREMESTFPEDSDGTIRKHIVFPTAVSSEKIPGTGLELPITQAEATSPIPEAEEAYQEGADRSGGEVEKEPTETKTGWIAGDTRLASYFRDYESPTLSKDNEGHPALAVPDFQPEGTMGRLDRKTSVTTVYKKVRDLQYGDKKEEPNLAFVSQEEQENSSFTILYEEPLQNEDKYTTTEVRRTHSLLIPHTAPNSMPVFACERSESRTDLVHHFEKEAKLGDAFDSDSSETFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGRHGASKSRENASQPSSVLSLLQSVSERLKMNFDEDDRQEGGEEEEEEDEEEPLHKGSLRAQRQETVTFKQPDSSLTFCSDDDRESTGVSKNSYVMSNEPTTSNLQIGLWPEKASFLQKSDLTSKLHSSLKSAYHQYLQTSKTHSSEKGARFGGIFQEPVSKYFRTQDTPGRLSPFTENVDKQTLKCNPRPGKMVIYDLHRRKYKQEIYCNIPDATSWSYPNGVLIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWLLQNRKHPQRNFVLGSIKRVLKDCSIPEIELCPQSDPACCPIYIQRAVPNLEELNIPKSVSFTVKSGVWLAYPDINFKGQAIVLEEDHGLFEISAAEIKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNDVDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNAFGALSGSILSFRYLQANFIESSITLFESDLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNTIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTKEVLDLTSSFMPCSFKVLRGCWLLYYQEGVSTNQCVLEEGLYADLTSCGCPTSRVKSLKPIDYVFEEPSLSLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGPNFLGRQILLEPNEIPNWRAFSGWKTIGSLRPVKQPSVYIRIRNRAQDGYLTVTGNVADTRATSVCISPYSGKNTQIWHYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRLNRNGTISSYLSDQLVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL", "length": 2705, "header": "tr|F1MTZ5-1|G3MZ11_BOVIN Computationally mapped isoform of Crystallin beta-gamma domain containing 3 OS=Bos taurus OX=9913 GN=CRYBG3 PE=3 SV=3 CANONICAL=G3MZ11-1" }, "locus": { "chromosome": "1", "start_pos": 42196078, "end_pos": 42121521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032404.7", "url": "https://www.ensembl.org/id/ENSBTAT00000032404.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032337.5", "url": "https://www.ensembl.org/id/ENSBTAP00000032337.5" } ] } }, { "isoform_ac": "G3MZ11-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ11/entry", "sequence": { "sequence": "MSGGRRRGGAPWHSFSRFFAPRSPSRDKEEEEEERPGTSQPPAPGRDAASVENEPMSTSQKKENILSSEAVKISQSEDRRTQAQQLITLPTQEDSKKPNDLSSSTSEAKIGESDKQTKESFFQFLGNLFNISGKSSLSEAKQSSFKDEHDKPEKDLRNPSRHEEGGQRESAGGSLRTQALPAEEQSSSAELSDAFSLDTTQDSEQETSDLLKQMDGKSERPLVTYATYRGPRQIKKYLKQQTVSETVNPLDRENASSDSSTSTHRGPGSEMEAGMVLLLSSASTGIPVKGQGPEGQLEDSDDNERDLNTGSHSTNNQGLANTASSRGVLNKAYPGGPETSRSSHSVTSSSSTAGDSDSRHHLSCAPGSQTDRNLGCSALCTESNSSKIPYSPDLERTATPGTVVKRTSSVMSDGTPVQAENSAVADFSCSKSDGSDPTTLRSADLLSPNKSIRREALQLPESKCSNKQAVENSSKQPANHTSSMAFQKQAVTDTELVNAGNRSSAQDTQKNLAPAEIKPETENTSGEEPTASSHVKAPEDRIESLHKDTDLLLLTEVKNLVRPHGKVPPFRMNQKEAASVKHTSESVVVTCLENKIAPELNIELNRNHISESLLDSESPQQAIASPDARTSPSLGHKSDFSASHPTFVSRVGMLSQVDIPILKNEGSSVLVETGDVNIVGISSQPPQCQQEHVANHVEATDRKSLPAGLHSKYAPTALESKEVLPDREKCQFLLDLEASDTDITAVDLSFEPASLSQDPEKAESVLSSTAASESTADKLDSSFSLETKTDSIAEMLPEADIGGQNNVPVESHSETGKTLSLSKIPVTRTEPRDISQDEISSPLDITGVPANPALSELTSLEVEQDKIFQLVDHEEIKEKYLDASLKESCQTEVSPSASKYQGVQGTEVGACRALPACLQSNRPETSPPVHDEKVTRQVAQNCAARASIIHPPSVPCGSKKIFDFSQLSLANTSPKFQETDSTKAKSPFLGSGISLRKEAFASEDSSFLPNPSVLRTEKRASSPRNKEDAHSLRGGTHSLPSSSSNSEVSMVRSSYNPTNNFSSVKVPIDVTHEGASLTNLLDPKSSYLESETSDLTGAEVTPLQDHLGDPTGMVSLDFPTAAQFDNPLEAATGAVAGTPASVNSSSQQCSEASAEHTEARKRAHAQLLDLESDFCKKAVTLIGEAFNSVREELKSKHSVGTCQEHRAIDSIMNPGTLEEDIPEKNPSEVTLTEIQSTEHLEEQAVENIPEVQGEEKACVSPVVGENSLLFNSDKMNVCWLLEDRARELVNQIIYSAQETVANDAQGTSDSELQANTSEILRSDSVQPCDMVREFLVSEQAINQSTCEISGKVLGRFFAESNLGSDTESIRGREIVLYQKSPFSGTRDGQSDSINLQESDTVLLAENIPLTGLDDKAKTHSFLKEDSKEKMGTECVDNHKPETEDTRTLVLNFKWPPFVNDDTHVPGTSKSSLSDTYVCLSEKSLPGHSNKSTSLAMSEVGKIHKDTEVNIGKIELIPSMVEMGKPNKKDAELNIMKYEAVPPMSEVGRAHKEDAELSTSETEPTAEILKMREAYQMDAERYIEKTEGLPATLEMENICQKDAEGDIAKTEVTPVTLEMENIYQKHAEGDVGKTGMTSVVSEMDSIYQKDIEGTAEKPESIPARLEMESIYQKDAEGKVDKTGVMSLTLEVVNVYRKDGEGITAKTEGPLLDLENTYQNGAEGVIRKTEMMPPFVLEMKEAPQKAVPASFEICKGDMKETSRGTLSTPSKREMESTFPEDSDGTIRKHIVFPTAVSSEKIPGTGLELPITQAEATSPIPEAEEAYQEGADRSGGEVEKEPTETKTGWIAGDTRLASYFRDYESPTLSKDNEGHPALAVPDFQPEGTMGRLDRKTSVTTVYKKVRDLQYGDKKEEPNLAFVSQEEQENSSFTILYEEPLQNEDKYTTTEVRRTHSLLIPHTAPNSMPVFACERSESRTDLVHHFEKEAKLGDAFDSDSSETFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGRHGASKSRENASQPSSVLSLLQSVSERLKMNFDEDDRQEGGEEEEEEDEEEPLHKGSLRAQRQETVTFKQPDSSLTFCSDDDRESTGVSKNSYVMSNEPTTSNLQIGLWPEKASFLQKSDLTSKLHSSLKSAYHQYLQTSKTHSSEKGARFGGIFQEPVSKYFRTQDTPGRLSPFTENVDKQTLKCNPRPGKMVIYDLHRRKYKQEIYCNIPDATSWSYPNGVLIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWLLQNRKHPQRNFVLGSIKRVLKDCSIPEIELCPQSDPACCPIYIQRAVPNLEELNIPKSVSFTVKSGVWLAYPDINFKGQAIVLEEDHGLFEISAAEIKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNDVDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNAFGALSGSILSFRYLQANFIESSITLFESDLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNTIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTKEVLDLTSSFMPCSFKVLRGCWLLYYQEGVSTNQCVLEEGLYADLTSCGCPTSRVKSLKPIDYVFEEPSLSLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGPNFLGRQILLEPNEIPNWRAFSGWKTIGSLRPVKQPSVYIRIRNRAQDGYLTVTGNVADTRATSVCISPYSGKNTQIWHYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRLNRNGTISSYLSDQLVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL", "length": 2903, "header": "tr|G3MZ11-1|G3MZ11_BOVIN Isoform 1 of Crystallin beta-gamma domain containing 3 OS=Bos taurus OX=9913 GN=CRYBG3 PE=3 SV=2 CANONICAL=G3MZ11-1" }, "locus": { "chromosome": "1", "start_pos": 42196078, "end_pos": 42070652, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063463.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063463.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054801.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054801.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1138, "start_aa": "Thr", "end_pos": 1138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1138", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 530, "start_aa": "Thr", "end_pos": 530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr530", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:516526", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516526", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LUY9-1", "protein_name": "Crystallin beta-gamma domain containing 3", "gene_name": "CRYBG3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGGRRRGGAPWHSFSRFFAPRSPSRDKEEEEEEKPGTSQPPAPGRGAASVENEPMSTSQKKENVLSSESVKIPQSEDKRSHAEKLITLPAQEDSKKPNDLSGSTSDAKIGESDKQPKESFFQFLGNLFNISGKSSLSEAKQSSFKDEHDKTEKDLQNPTEHHEEGVHRERATVSGSLETQVLPAEQESNSAELSDAFSLDTAQDSEQETSDLLRQIHDKPEKPLVTFSTYRGPRQIRKYLKQQSASETVNPSDRENESSDSSGSTQMGPESEMEPGIVPVSSASTDISMKGHLLEGLLEVSDYNKINLNTEGHSRNHQELPNTASSKDVFNKNDPEGPERSRSSSSVTNSSPTLGESDSQHHFNCAPVSQMDRNLVCSTLFTGSKSSKTPCSPDLQRTASPETMIRENISVVSDGTVVQREEHAEPESPAVSDFSCSKSNGNDTTKQRSADLPSPNKSIRREDLQLPESKCSDKQTIDNSSKQAANHTNTVALQRHAVTDTELGNEGNGLSSQDTQENLAVTENKQEAESASVGEPTTSSHVKESRIESLPKDTDQPLVTEAIKLDFRPHGKMPSIGINQKDPASVKYTGESAGIACLENEIAPRLNFELNRDCISESLLDSERPQQAKVLPDVRTSLNLDHKKTDFNTSFPTFVSGVAVMNKLDIPVLKNKDSSVLIETGDVNIVGISSQPSKRQEENVADHVEAMDRENLPACLHPKHASAVLEYKEVLPDSEKCQFPLDLKASDTHLTAVDLSFKSESLFKDHSSISSQDPNKTELMLANTKACKNTLERPDSSFSLETKADNIAEILSKTEVSGQNSVPIESHSGRGKTLDSSKIPVSQIEPRHISQDKISSLLEIIDVPAKPMLTELISLEVEQDKSFQSLDHKDTKEKYPDAGLKENCQTEVSPSVSNHQGIQEMEVEALGGPPALLQSDRPEILPPVHDKKVTRQMAQNCEANICAIHQPLVICGTKNISGFSEMAELSLTNTSPKFQETDSMKVSSPLLSSGISLEKNPFASEGSSFLMNASVLRSPKKVSSHRKKENMHFPSGGTDIMSLSSVNSGEVSKVIRSHNHPSNFDSVKVTIEVTHEGASLTNPLYPNSSYLEVETSLPTGAEVTPLQDHLGSHPETVSLDFPTAAQFDNPMETETGAVAGAPVSVNSSSWQCSEASAKHIETRRRAHDQFLDLKSGLHKKAGTLIGEIFDSVTEELKSKHTVGTLEEHTATDGIMNPGTLKEDIPSEVTLPGIQLTEHFEEQLMENMSEVQGEEKACVSPVVGEKSLLFDSDRIDVSWLLEDQARELVNEIIYSAQETLTNDAEDAWDSELQTNTSEILNSDDVKPDDRVREFLVSEQTANQSTCEISEKVLGRFFAVNNLVSDTESIKGREIGLYQNSPFSENRAGQSDSINLQESDAILLAEDMPHTGLAIKAETHSFLHKDSKEKMEIECVDNHKTETEDTRTSKSILSNALVCISEKSFPEHSNKSTPLTTSEVGQVHKEDDEVYIGERELIPSMLEAEKTNKKDAELNIVKYDAVPPLSEMGRAHKRDAELSISKTEPTADILKMREAYQMGTERCIEKTERLPATLEMEKAYKIRDTKGDIGKTDMTTLMSELKNVYQKDAEGITGKTEVIPATLEMESIYQKDAEGDIAKTEVMPVPLEMKSISQKHAEGDIGKTGMTSVMSEMENIYQKDVEGTAEKVEMIPATLEMEHVYQKHAEGEVDETEAIPIMPIMVNVYQKEGEEIPAKTESPVLDTENTHQKDAEEVIRKTKIIPPFALKVKEAHRKAVPASLEMDETCKRDAKETIGMIVSVPSKIEMERTSPEDYDGAVRKNRVLSTVVNVEKTHETGLELPITQVEATPPIFEAEKAPQEYAKGSAGETEKEPTEMKAGLIACDSRLASYFKGYESPTLSKDYEGYPALVQGFQPEDTVGRLDRRTSVTAVHKQIRDLGYGNEKEEPNLAFISQDEQENSSFTILYEEPLQDEDKYATAEVRRTHSHIIPDTSTDSMTVFTCERSESRTDLIHHFEKETKLGETFESDSSEIFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGHYGSTKSRESADQPSSVLSLLQSVSERLKMNFGEDDRREGWEEENEEEEEETFHKGSLRARRQETVTFKLPDSSITFYPDDGQESTGISKNSYVMSNEPTTSNLQIGLWPEKASFLQKSDLTSKLHSSLKSAYHQYLQTSKTHSSEKGARFGGTFQEPVSKYFRVQDTSGQLSTFTENVDKQTLRCNPRPGKMVIYDLHGSKYKQEIYCNIPDATSWSFPNGVLIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWILQNKKHPQRNFVLGSIRRVLKDCSIPEIELCPQSDPARCPIYIQRAVPNLEELNIPKSVSFTVKSGVWLAYPDINFKGQATVLEEDHGLFEVSIAEVKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNDVDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNACGALSGSILSFRYLQANFIESSITLFESDLESGKFINITNQEISDLEEIGFGSETRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPVQLEPLGINEPPHLLKAFSKPGFQGECIDFTKEISDLPSSFTPCSFKVLRGCWLMYYQEDISNNQCVLEEGLYADLTSCGCPTSRVISLKPIDYVFEEPSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLEPNEIPNWTAFSGWKTIGSLRPMKQPAVYIRIKNRAQDEYLTVTGNVADTRATSVCISPYSGKNTQIWHYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQLRQKWRLNRNGTISSYLSDQLVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL", "length": 2951 }, "evidence": [ { "id": "G3MZ11", "url": "https://omabrowser.org/oma/group/G3MZ11/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RDY6-1", "protein_name": "Crystallin beta-gamma domain containing 3", "gene_name": "Crybg3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGRRRGSAPWHSFSRFFAPRNPSRDKEEEEEEKPGTGQPAGANRSAASAENESMSTSQKKENAPSSEAVKIPQVEDRRNPAEQPAILPMVDDPLKPKDLPDSTVDAKTGESDRQPKESFFQFLGNLFNISGKSSLGEVKQSSFKDDQDKPEKDPQTPTGPPEEGSQREKEITSCPVRTRILPEDQRESNSSELSDAFSLDTTQESEQETTDTLKTDTAGKPEKPSVTYATYRGPTQIRKYLKKQPGSETVNHLNREDGNSDSSTQARTGSRSIPDTVTVPLSTASKDVTTKGHLLGGPLEVSGYSQTNTNIENDLESPPELQKIASSKYILNKNSLGDPSSSWASPSSVSNPSYVVGEPDSQMERSLVCSSVFRGSKSSQGPCPEFQRKTATENTLRVNSSAVSDGLPSVPAEERVQPQRPAVSDFSCSKSDGSDTTKMESTNLSSPNKSIRHEDVRLPESKCCDKPAVDNPSRQDVNHTRVTTLRGHAVTDSGLVNEGKKLPAQDKQKNVLSEVLRETECASGSEPTTYSHVRAPEVRIESLPKETELPCDTETEKLGVEPHVQTPPQEMGETQEDPGSVKSVSDSVGIACTESETAHELKSESNRNPISDSPCLLEPLQQGEVFSEAETPLNLDCKTSDCSASPPTSASRTDRLGQLGFPGLKGERSTSSRTGQGNVCSHPNECREAVGAHSVAADRENPRAPRQLRQASAIVDSKDILRDGEKCQFPSGPETPGTHSAGLGLLNFEPGDLSENLNSVPSHSPKKAALVSSSAKASRSPVEKSDSLPLETQTAKMLGNLEVCDQSSFLVELSSGRGKTLSVPPVSQAEPRDVSQCDISSSQGTAAEKLSETVLSELNYLGMEKDKDAQPVDHRESKELCCSGGFKENHQTGIPPASKHQSVQETEINTLGTTASILRSRLPGINLAPEEESTRHMAQNCKASTSLLSPSFAVCGTKKSSSISEMEELRLDNISPKFQETDNTQVYTSFLGSDGRLEKNVLAPEVSSSLNVPSLPGLEGEDSSHGDNSYFQSAGTGSTSPSCHSKGDSTDVNSHDLPSNFESLKVNVNLTGEGASVTDPLGHNSFYLALDIPNPKETDMTSIQGGLGTHTRKASLDSPTTAYFDNPMKAETGTVAGAPVSVNRSCQQCSEASADQTEARRRAHDPLLLRSSLLAKADTLTEEILSSIREELKSKHTVGSCQEHLAQDDIMNPGTVKEAIPSEVVLAGIQLKESLDEKGVDNMSEVKEEEQTSVSSVVSETSLLFDLDRVHSSYLLEEQAKELVNEVTYAVQENLLNDAFDEIENTWVSEPQADPSNIWNSNGGDEPHALVREFLVAEQTVNQSTCEISENEVLSKFSSVSHLLSGTESVKGREIVPYQESPGFGSGAGQSVSRKLQRSETVVQAEGMPPTSLEGKVRPRLFVSEDYRKAAETECVDNHKMATEETRTLVLNFNLPLANDDIHAPGTSKSSFSDSLVCISEKSLPWHNKSMPLVMSDLGKAYKIDNEVNVGKMVALPSMLETGKTNKRDAELNIRKHEAAPLMPHREKTCKMDAELNIMKAEPEVNMFTRGGVYQMDAQMHVEKPEDLPVTLGMEKAYKMDSEGDIGKADVMPVMSELKALHLKDAEGDIAKTEVAPISIEMESFYQKHAEGDVGKTGVASVMSDVDIFYQKDVVGISPKAEVTTVTLGMEDTYQKEEESDVAKTDVTGMVPAELEMEDTYPKGSEGDTDSTEGKPIRLEVINIYQKYSDRVTGKMGRPMSPLRDAEDVLGNSETVPFVLDVKETYQETVHSPLDILEKRVQRDTEETNGTEPVPSEINMEVMAPEDSSGSIKNPEVGTEVAIESTNRTTPEVTITRMEAMGPVYESEMGPQEYMEKSIGELEELSSEVKEGLILHGDRLASHFRGYESPTLSRDYEGYPALAMPDFQEEDTVVRLNKIMSVPAVDDKRRDMDYRGEKEESDLAFVSQDEQDSSSFTILYEEPLQEEDKKISAEVRGTRSLLFPDTSSSGMPGLACERSESRTDLVHHFEKEGKLAEAFDGDNSEMFLSVEAKRYKIYPLALSPIYEDDSSQEDVLSNEVSPGHHGSTKSRESANQPSSVLSLLQSVSERLQRNFDGDDGDDRQVAEEEEEEAAVAAASGKGLRTERRERVTFHLPDPSITFYPDDDQESAGISKSYVEFSEPTTSSLQHSLWPEKVPFLQKSDLTSKLHSSLKSAYHQYLQTSRTHSSETGTRFGGTLQEPVSKHFRVQDHAGRLSAYMENVDRLTLRCNPRPGKMIIYDLHGSKYKQEVYCNIPDATAWSFPNGALIKVVRGCWILYEKPHFQGQKCVLEEGEKVLNRDWLLQNRKHPERTFVLGSIKRVLKDCSIPEIELRPKSDPGWCPIYIHRSIPNLEELNIPKSSTFTVKSGVWLAYPDVNFKGQATVLEEDQGLFEISAAEMKSLQTLQMGGLKVEMPMNLKVIIYEKPHFRGHAKEFSEHIESVPKFLKSDKDFRGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSSACGALSGPIMSFRYLQANFIESSITLFESDLESGKFIDITNQEISDLEEIGFGRETRSIHVKSGAWVAYHQKFFCGDQYILEKGKYKCFFDWGGSSNIILSIRPIQLEPLGINEPPHLLKAFSKAGFQGECIDFIKECADLTSFTPASFKVLRGCWLLYYQEDGFYHQCVLEEGLYTDLTSCGCPSARVRALKPIDYFFEEPSISLFALEHCEGRELHLEDAVNSVLNKDLHFYTQSVWIKSGLWIAYEGSNFLGRQILLVPNEIPNWTAFSGWKTIGSVRPMRQPAVYIRIRNRAQDEYLTVTGNPADARTMSVCVSPYSGKDTQIWHYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRMNRNGTISSYLSDELVLDVKGGNYCDKTHVIVNQPLEGEETQKWDIEIL", "length": 2952 }, "evidence": [ { "id": "G3MZ11", "url": "https://omabrowser.org/oma/group/G3MZ11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68DQ2-3", "protein_name": "Very large A-kinase anchor protein", "gene_name": "CRYBG3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGRRRGSAPWHSFSRFFAPRSPSRDKEEEEEERPGTSPPPAPGRSAASVENEPMSTSQKKENVLSSEAVKIRQSEDKRNHAEKPVTLPVQEDPKKAYDLSSSTSDTKIGESDRQPKESFFQFLGNLFNISGKSSLGEAKQSSFKDDQDKTEKDLQNPSDHHEDGIKREREIFSGSLRTQTHPTEEQDSNSSELSDAFSLDTTQDSDQETTNLLKQIDGKPEKPSVTYATYRGPRHIGKYLKQQTGLATVNTLDRENESSDSSTNRHIDPGSEIEAGVLPLLLSASTDSSMKGNLLEGPLEDSDCSKTSFNKENSLTNNPELQNIASSNNLLNKNAWGSIERNRSSPSSVTNSSYDGESDSQHHLSCEPVSQTNRNLVCSALLTGSNHRKVPCSPDFQRVTTTENTIKENSTVMSNRTLVQREELVEPQGPAISDFSCSKSDGSDTTEQESTNLPSPNKSIRHEHLQLPESECSDKQTIDSSSKQAATHTNIIALQRHAVTDTEFVNEGKRLSAQDSQKNVAVREIRRETESASAGESIASSHVKAPEDKIESLPKDTDQYFETKAKKLDFRSHDKIPHIRMNKKDLASLNYISESAVVASLGNENAPELKFELNRSHISETPLDSESPQQAEVSPDAKTSLSLDCKKLNFSISPPTFVSGVGMLSKLDIPDLMNEGSPVPIETGNVNIVGISYQPRKCKEENVKNHVEAAGRKSPPPSFCLEYTSAIFEFKEVLSNSEKCQVLPGSEASGPHLTGLELLSFDSGNLSKDCSSILSQDPNRVELVSSNTKANMSIIEKSDSLSLEAKTANIVSKAEIDGQNNVLVESHSGRGKTISLSKVSLSKVEPRNISQDKMSSFPLKITHVPEKPILSELTFLEVEQGKRFQSINHNEIGEKCSDAGLKENCQAELSPAASKYEDKPEPEVDALGSPPALLKSNISWILPPIHDEKISRQMAQNCEAHTCVFHQSLDICGTKKISGHSEMAELSLTNISPKFQETGSMKVNSPFLDSDSSLEKNSSASEDSSFLKVPSVLKLEKKSSSYRKKENIHFLNGGIDSVSSSSSYPEEVSMIVNSHKPQNNLDSIQVTKDLTHEGTSVTNLLYPTTSYLEFETSVSIGTEVTPFQEHFGIYTGKISIDFPTAAQFDNLVEAETGAVAGPAASVNSSGQQCSEASAEHIEARRRAHDQLLDLKSSLLKKADTLIGEIFNSVREELKFKHTVSTCQEHIAIEGIMNLGTLKEDISEKNPSEVTLTEIQQTEGLEEQGMENMSEVKEKPCVSPTVGEKNLLVDPNSMNVSCLLEDKARELVNEIIYVAQEKLRNDTFEDTEDTWDSELQANTSKILNSDSVKPHDVVREFLVSEQPVNQSTQISENKVLNEFFSLSNLASGTESIKGGEIVLYQKSLFSGNGSGLSDSINLQESDTVLLAEDMSHKRLDDRVKTHLFRSEDCNETMEIENVDNNKTETEDRRTLVLNFKWPPLVNDDIHAPGTSKSSLSDSLVCISEKNLPGHSKNTPLAMSDVGKVHKKDNEINIGKIELIPSMLETGKTNKKDAELNILKYEAVPPMIEMGRIHKMDAELNVTKTEPKANVFKMGEVYQMDAESCIEKTEGSAVILGMEKAYKMKDTEGDIGKIEVIPMMPEVKNIHQKDAEGDIVKTEMTPVTVDMENIYQTHAEGDIGKTGTIALSEVENIHQKGGEGISEKAEVIPVTLAMENTYQKDAEGDIGKAEVMPVRLEMENTYPKDTERDGGKTEVMPLALEVVNTYQKNAKGFTGNTEGSVLKMEATYRKTAEEVIKNTEIVPCVLKVKEAHETAPAPLEMEKACKRDVKETIGATVSTPSVIEMEKISPEDRGENIGKHKVLPAVVDIEKIHGTGLELTTKQGEAMLPAFESKTPQEYAEGSVEETKEEPTEIKEGLIAHENRLPTYFRGYESPTLSKDYEGYPAPAMPDFQPGDTTVRLDKRMSLTAIYDKRRETDYSDKGYNLAFVSQDEQENSSFTILYEEPLQEEDKYASAEARQTQSVLFHDTSADSMPVLACERSESRTDLVHHFEKGTKLGETFDSDSSEMFLSVEAKRYKIYPLALSPIYEDDSSQEDILSSEVSPGHHGPRKSRDSENQSSSVLSLLQSVSERLKMNFDEDDREAADEEEEEEEAAVLHKGDLRAGSGERVTFQLPDPSITFYPDDQESVGISKNSYVMPNEPTTSNLQVGLWPEKTSFLQKSDLTSKLHSSLKSAYHQYLQTSQSHSSEKGARFGGIFQEPVSKYFRVQDSPGRLSPFIENVDKQTLRCNPRPGKMVIYDLHESTYKQEVYCNIPDATSWSFPNGVLIKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSIPEIELFPQSDPACCPVYIQRAVPNLEELNISKSVSFTVKSGVWLAYPDINFKGQATVLEEDHGLFEISTAEMKSLHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSNACGALSSPILSFRYLQANFIESSVTLFESDLESGKFIDITNQEISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPIQLEPLGINEPPHLLKAFSKPGFQGECIDFTEETSDLTSLMPCSFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCGCPASKVKSLKPIDYVFEEPSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSGLWIAYEGSNFLGRQILLRPNEIPNWTAFSRWKTIGSLRPMKQPAVYIRIKNRAQGEYLTVTGSLADTRATSVCISPYSGKNTQIWYYCRGLFKSKASDTCLDVIGGRDTPGAKVALWTEHGQFRQKWRLNKNGTISSYLSDQLVLDVKGGNYCDKTHVIVNQPLEGEETQKWDIEIL", "length": 2970 }, "evidence": [ { "id": "G3MZ11", "url": "https://omabrowser.org/oma/group/G3MZ11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80W49-1", "protein_name": "Beta/gamma crystallin domain-containing protein 3", "gene_name": "Crybg3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPVVYDKRRNLDCREEKEESNLAFVSQDEQDSSSFTILYEEPLQEEDRYTSAELRGSQSLLFPDTSSMPGLACERSESRTDLVHHFEKEGKLGEAFDGDNSEMFLSVEAKRYKIYPLALSPIYEDDSSQEDVLSSEVSPGHHGSSKSRESANQPSSVLSLLQSVSERLQRNFDGDDRQEAEEEEEEAVASGKDWRTEKREHVTFHLPDPSIPFYPEDNQEHAGIFKSYVEFSEPTTSSLQHGRWSEKELFLQKSDMTSKLHSSLKSAYHQYLQTSRTHSSETGTRFGGTLQEPVSKYFRVQDHAGRLSPYVENVDKQTLKCNPRPGKMIIYDLHGSKYKQEVYCNIPDATTWSFPNGALIKVVRGCWILYEKPHFQGQKCVLEEGERVLDRDWLLQNRKHPERNFVLGSIKRVLKDCSIPVIELCPKTDPGCSPIYIHRSVPNVEELNIPKSTSVTVKSGVWLAYPDIHFKGQATILEEDQGLFEISAAEMKSLHPLQMGGLKVEMPMNLKVILYEKPHFLGHTKEFSEHIDSVPTFLKSDKDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSSACGALSGPIMSFRYLQANFIESSITLFESSHLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYHQKFFCGDQYILEKGKYKCFFDWGGSSNTILSIRPIQLEPLGINEPTHLLKAFSKAGFQGECIDFVKECADLTSFTPASFKVLRGCWLLLYYQEDGFYHQCVLEEGLYVDLTSCGCPSARIRALQPIDYVFEEPSISLFALEHCEGRELHLEDAVNSVLNKDLHFYTQSVWIKSGLWIAYEGSNFLGRQILLTPKEIPNWTAFSGWKTIGSVRPMKQPAVYIRIRNRAQDEYLTVTGNPADARTMSVCISPYSGKDTQIWHYCRGLFKSKASHTCLDVIGGRDTPGAKVALWTEHGQLRQKWRMSRNGTISSYLSDELVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL", "length": 1005 }, "evidence": [ { "id": "G3MZ11", "url": "https://omabrowser.org/oma/group/G3MZ11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ], "pmid": "" }, { "name": "structural constituent of eye lens", "id": "GO:0005212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005212", "evidence": [ { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ], "pmid": "" }, { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002088", "evidence": [ { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "G3MZ11", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1315, "end_pos": 1317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1342, "end_pos": 1344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1489, "end_pos": 1491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1926, "end_pos": 1928, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2046, "end_pos": 2048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2578, "end_pos": 2580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2858, "end_pos": 2860, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ11" }, { "id": "PS50915", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50915" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta/gamma crystallin 'Greek key'", "eco_id": "ECO_0000259", "start_pos": 2266, "end_pos": 2315, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 530, 1138 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1060, "end_pos": 1062 }, { "start_pos": 1143, "end_pos": 1145 }, { "start_pos": 130, "end_pos": 132 }, { "start_pos": 1315, "end_pos": 1317 }, { "start_pos": 1342, "end_pos": 1344 }, { "start_pos": 1489, "end_pos": 1491 }, { "start_pos": 1926, "end_pos": 1928 }, { "start_pos": 2046, "end_pos": 2048 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 2578, "end_pos": 2580 }, { "start_pos": 2858, "end_pos": 2860 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 523, "end_pos": 525 }, { "start_pos": 971, "end_pos": 973 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3XCF6-1", "uniprot_ac": "G3XCF6", "uniprot_id": "G3XCF6_BOVIN", "mass": { "chemical_mass": 106485.0, "monoisotopic_mass": 106485.0 }, "refseq": {}, "gene_names": [ { "name": "NFATC1", "type": "recommended", "evidence": [ { "id": "G3XCF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3XCF6" } ] } ], "protein_names": [ { "name": "Nuclear factor of activated T-cells, cytoplasmic 1", "type": "recommended", "evidence": [ { "id": "G3XCF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3XCF6/entry#names_and_taxonomy" } ] }, { "name": "NFAT transcription complex cytosolic component", "type": "synonym", "evidence": [ { "id": "G3XCF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3XCF6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGN8#function" }, { "database": "UniProtKB", "id": "ARBA00058891", "url": "https://www.uniprot.org/uniprotkb/ARBA00058891#function" }, { "database": "UniProtKB", "id": "A0A3Q1M5J8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5J8#function" }, { "database": "UniProtKB", "id": "A0AAA9SHK0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHK0#function" }, { "database": "UniProtKB", "id": "G3XCF6", "url": "https://www.uniprot.org/uniprotkb/G3XCF6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3XCF6", "url": "https://www.uniprot.org/uniprotkb/G3XCF6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NFATC1", "url": "https://www.uniprot.org/uniprotkb/G3XCF6", "locus": { "chromosome": "24", "start_pos": 780448, "end_pos": 867162, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000656", "url": "https://www.ensembl.org/id/ENSBTAG00000000656" } ] } } ], "crossref": [ { "id": "G3XCF6", "url": "https://alphafold.ebi.ac.uk/entry/G3XCF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000656", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000656", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07881", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07881", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511224", "url": "https://www.ncbi.nlm.nih.gov/gene/511224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LGN8", "url": "https://www.orthodb.org/?gene=A0A3Q1LGN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M5J8", "url": "https://www.orthodb.org/?gene=A0A3Q1M5J8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3XCF6", "url": "https://www.orthodb.org/?gene=G3XCF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12533:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12533:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00554", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00554", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2025928", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2025928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2871809", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2871809", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5607763", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5607763", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LGN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5J8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHK0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHK0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3XCF6", "url": "https://www.uniprot.org/uniprotkb/G3XCF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3XCF6-1", "url": "https://www.uniprot.org/uniprotkb/G3XCF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRLFKSEIQACVQALTISLFPPEHYGYAAPGLGAGLPLSAAHPSLPAPCHDLQSSAAGVSAVGYGGTVDSGPSGYFLSSGGIRPNGAPALESPRIEITSYLGLHHNSSQFLHEVDVEDVLPKRSPSTATLNLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESSFSYPYASPQTSPWQSPCVSPKTTDPEEGFARGLGACGLLGSPRHSPSTSPRTSVTEESWLGARTSRPSSPCNKRKYGLNGRQLSCSPHPSPTPSPQGSPRVSVTDDTWLGNTTQYTSSAIVAAINALSTDSSLDLGDGVPVKARKTTLDHSPAVALKVEPAGEDLGTTPPTPDFQPEEFAAFQHIRKGAFCDQYLSVPQHPYPWARPRSPASYTSPSLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPSVQLHGYVESEPLTLQLFIGTADDRLLRPHAFYQVHRITGKTVSTASHEAVVCSTKVLEIPLLPENNMRATIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPNGRTLSLQVASNPIECSQRSAQELPLVEKQSAASGPVLGGKRMVLSGHNFLQDSKVIFVEKAPDGHHIWEMEAKTEGDLCKPNSLVVEIPPFRNQRITSPVQVNFYVCNGKRKRSQYQHFTYLPANVPIIKTEPSDDYEPALTCGPMSQGLSPLPKPCYGQPLALPPDPGACLMPGFPPRPQGSASPELHDLSCAPYGSATAGPGHSPLGLPRPVGGVLASQEAPRPSGVPPGPPQPPPPTLLQPQVSPTSSGSCSPGRRPALCPHSPSSPLPPGTRELTRLQPCGPAHPCGTGHQQHQPPEVPSSEPAAARPPPPPEVREDSNRSLAPIPVTVKREPQELDPLDLDDGKCPPQQARAQPWAEGPRPGACPPPRECAWHVSHQEVPAVSSATAGQWGTPSPPRGCLFCASWGHVVPVAMPGVVTMVPGTRPLPAEMSREDKRPPWTRLWAQLVA", "length": 997, "header": "tr|G3XCF6-1|G3XCF6_BOVIN Isoform 1 of Nuclear factor of activated T-cells, cytoplasmic 1 OS=Bos taurus OX=9913 GN=NFATC1 PE=4 SV=3 CANONICAL=G3XCF6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LGN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGN8/entry", "sequence": { "sequence": "MTGLEEDQEFDFDFLFEFNQSDEGAVAAPAEHYGYAAPGLGAGLPLSAAHPSLPAPCHDLQSSAAGVSAVGYGGTVDSGPSGYFLSSGGIRPNGAPALESPRIEITSYLGLHHNSSQFLHEVDVEDVLPKRSPSTATLNLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESSFSYPYASPQTSPWQSPCVSPKTTDPEEGFARGLGACGLLGSPRHSPSTSPRTSVTEESWLGARTSRPSSPCNKRKYGLNGRQLSCSPHPSPTPSPQGSPRVSVTDDTWLGNTTQYTSSAIVAAINALSTDSSLDLGDGVPVKARKTTLDHSPAVALKVEPAGEDLGTTPPTPDFQPEEFAAFQHIRKGAFCDQYLSVPQHPYPWARPRSPASYTSPSLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPSVQLHGYVESEPLTLQLFIGTADDRLLRPHAFYQVHRITGKTVSTASHEAVVCSTKVLEIPLLPENNMRATIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPNGRTLSLQVASNPIECSQRSAQELPLVEKQSAASGPVLGGKRMVLSGHNFLQDSKVIFVEKAPDGHHIWEMEAKTEGDLCKPNSLVVEIPPFRNQRITSPVQVNFYVCNGKRKRSQYQHFTYLPANVPIIKTEPSDDYEPALTCGPMSQGLSPLPKPCYGQPLALPPDPGACLMPGFPPRPQGSASPELHDLSCAPYGSATAGPGHSPLGLPRPVGGVLASQEAPRPSGVPPGPPQPPPPTLLQPQ", "length": 796, "header": "tr|A0A3Q1LGN8-1|G3XCF6_BOVIN Computationally mapped isoform of Nuclear factor of activated T-cells, cytoplasmic 1 OS=Bos taurus OX=9913 GN=NFATC1 PE=4 SV=2 CANONICAL=G3XCF6-1" }, "locus": { "chromosome": "24", "start_pos": 862344, "end_pos": 805602, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084092.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084092.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057672.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057672.2" } ] } }, { "isoform_ac": "A0A3Q1M5J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5J8/entry", "sequence": { "sequence": "MPSTSFPVPSKFPLGPPVAVGGSGETLGPSAPAGGTMKSAEEEHYGYAAPGLGAGLPLSAAHPSLPAPCHDLQSSAAGVSAVGYGGTVDSGPSGYFLSSGGIRPNGAPALESPRIEITSYLGLHHNSSQFLHEVDVEDVLPKRSPSTATLNLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESSFSYPYASPQTSPWQSPCVSPKTTDPEEGFARGLGACGLLGSPRHSPSTSPRTSVTEESWLGARTSRPSSPCNKRKYGLNGRQLSCSPHPSPTPSPQGSPRVSVTDDTWLGNTTQYTSSAIVAAINALSTDSSLDLGDGVPVKARKTTLDHSPAVALKVEPAGEDLGTTPPTPDFQPEEFAAFQHIRKGAFCDQYLSVPQHPYPWARPRSPASYTSPSLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPSVQLHGYVESEPLTLQLFIGTADDRLLRPHAFYQVHRITGKTVSTASHEAVVCSTKVLEIPLLPENNMRATIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPNGRTLSLQVASNPIECSQRSAQELPLVEKQSAASGPVLGGKRMVLSGHNFLQDSKVIFVEKAPDGHHIWEMEAKTEGDLCKPNSLVVEIPPFRNQRITSPVQVNFYVCNGKRKRSQYQHFTYLPANVPIIKTEPSDDYEPALTCGPMSQGLSPLPKPCYGQPLALPPDPGACLMPGFPPRPQGSASPELHDLSCAPYGSATAGPGHSPLGLPRPVGGVLASQEAPRPSGVPPGPPQPPPPTLLQPQ", "length": 808, "header": "tr|A0A3Q1M5J8-1|G3XCF6_BOVIN Computationally mapped isoform of Nuclear factor of activated T-cells, cytoplasmic 1 OS=Bos taurus OX=9913 GN=NFATC1 PE=4 SV=2 CANONICAL=G3XCF6-1" }, "locus": { "chromosome": "24", "start_pos": 866963, "end_pos": 805602, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074725.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074725.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065576.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065576.2" } ] } }, { "isoform_ac": "A0AAA9SHK0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHK0/entry", "sequence": { "sequence": "MPSTSFPVPSKFPLGPPVAVGGSGETLGPSAPAGGTMKSAEEEHYGYAAPGLGAGLPLSAAHPSLPAPCHDLQSSAAGVSAVGYGGTVDSGPSGYFLSSGGIRPNGAPALESPRIEITSYLGLHHNSSQFLHEVDVEDVLPKRSPSTATLNLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESSFSYPYASPQTSPWQSPCVSPKTTDPEEGFARGLGACGLLGSPRHSPSTSPRTSVTEESWLGARTSRPSSPCNKRKYGLNGRQLSCSPHPSPTPSPQGSPRVSVTDDTWLGNTTQYTSSAIVAAINALSTDSSLDLGDGVPVKARKTTLDHSPAVALKVEPAGEDLGTTPPTPDFQPEEFAAFQHIRKGAFCDQYLSVPQHPYPWARPRSPASYTSPSLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPSVQLHGYVESEPLTLQLFIGTADDRLLRPHAFYQVHRITGKTVSTASHEAVVCSTKVLEIPLLPENNMRATIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPNGRTLSLQVASNPIECSQRSAQELPLVEKQSAASGPVLGGKRMVLSGHNFLQDSKVIFVEKAPDGHHIWEMEAKTEGDLCKPNSLVVEIPPFRNQRITSPVQVNFYVCNGKRKRSQYQHFTYLPANVPIIKTEPSDDYEPALTCGPMSQGLSPLPKPCYGQPLALPPDPGACLMPGFPPRPQGSASPELHDLSCAPYGSATAGPGHSPLGLPRPVGGVLASQEAPRPSGVPPGPPQPPPPTLLQPQVSPTSSGSCSPGRRPALCPHSPSSPLPPGTRELTRLQPCGPAHPCGTGHQQHQPPEVPSSEPAAARPPPPPEVREDSNRSLAPIPVTVKREPQELDPLDLDDGVSLPCGFLKDSNCLAQPSSGSRREEPGRMVFKNLCS", "length": 947, "header": 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"Protein Classification" ] }, { "id": "IPR032226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034924", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034924", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541118", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541118", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LIC9", "url": "https://www.orthodb.org/?gene=A0A3Q1LIC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAD1", "url": "https://www.orthodb.org/?gene=A0A3Q1MAD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N978", "url": "https://www.orthodb.org/?gene=A0A3Q1N978", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MX25", "url": "https://www.orthodb.org/?gene=F1MX25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N258", "url": "https://www.orthodb.org/?gene=G3N258", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13020:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13020:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-426496", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-426496", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5578749", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5578749", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015315836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIC9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAD1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N978", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N978", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N978-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N978-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX25", "url": "https://www.uniprot.org/uniprotkb/F1MX25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX25-1", "url": "https://www.uniprot.org/uniprotkb/F1MX25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N258", "url": "https://www.uniprot.org/uniprotkb/G3N258", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N258-1", "url": "https://www.uniprot.org/uniprotkb/G3N258-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQQQQQQPQPQQQQPQQPQQPQPPPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLSSQSESSALTNQQPQNNGEVQISKNQSDTNHNTPGSHYENSERGPVSSTSDSRTNCKNAVVNDSPEKEAWPSAPGSDPELVSECMDADSASSSESERPITIMASGSTGGENDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQASVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSPLGQMPNNQSINSKVGGASTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSNTGAWRVSTMNHPQIQAPSVVNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSSPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAVNSQSASWGNGANSGGSRRGWGTPAQNTGTNTPGVEWNKLPGNQHSSDSANGNGKKFTNGWKSTEEEDQGSAASQTNEQSSVWAKTGGTVESEGSTESTGRLEEKATGENQSRDRRKMDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACVDKTSPSSNDTSSVSGWGDPKPALRWGDSKGSSCQGGWEDDSAATGMVKSNQWGNCKEEKSAWNDSQKNKQGWGDGQKSNQGWSVSAGDNWGERSNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPNPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPMPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGSSRSDQQAQVHQLLPSAGTISNKEASSGSGWGEPWGETSTPATTVDNGTSAWGKPVDSGPSWGEPIAAASSTSTWGSSSVGPQTLNKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMDRSPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPSLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRQQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQSLHQPAMKSFLENVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNAPLSSTAQSTAARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSSWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPSWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM", "length": 1948, "header": "tr|G3N258-1|G3N258_BOVIN Isoform 1 of Trinucleotide repeat containing adaptor 6A OS=Bos taurus OX=9913 GN=TNRC6A PE=3 SV=3 CANONICAL=G3N258-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIC9/entry", "sequence": { "sequence": "MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQQQQQQPQPQQQQPQQPQQPQPPPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLSSQSESSALTNQQPQNNGEVQISKNQSDTNHNTPGSHYENSERGPVSSTSDSRTNCKNAVVNDSPEKEAWPSAPGSDPELVSECMDADSASSSESERPITIMASGSTGGENDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQASVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSPLGQMPNNQSINSKVGGASTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSNTGAWRVSTMNHPQIQAPSVVNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSSPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAVNSQSASWGNGANSGGSRRGWGTPAQNTGTNTPGVEWNKLPGNQHSSDSANGNGKKFTNGWKSTEEEDQGSAASQTNEQSSVWAKTGGTVESEGSTESTGRLEEKATGENQSRDRRKMDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACVDKTSPSSNDTSSVSGWGDPKPALRWGDSKGSSCQGGWEDDSAATGMVKSNQWGNCKEEKSAWNDSQKNKQGWGDGQKSNQGWSVSAGDNWGERSNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPNPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPMPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGSSRSDQQAQVHQLLPSAGTISNKEASSGSGWGEPWGETSTPATTVDNGTSAWGKPVDSGPSWGEPIAAASSTSTWGSSSVGPQTLNKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMDRSPYFDKNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPSLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRQQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQSLHQPAMKSFLENVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNAPLSSTAQSTAARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSSWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPSWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM", "length": 1899, "header": "tr|A0A3Q1LIC9-1|G3N258_BOVIN Computationally mapped isoform of Trinucleotide repeat containing adaptor 6A OS=Bos taurus OX=9913 GN=TNRC6A PE=3 SV=1 CANONICAL=G3N258-1" }, "locus": { "chromosome": "25", "start_pos": 22479022, "end_pos": 22384650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076208.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076208.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058757.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058757.1" } ] } }, { "isoform_ac": "A0A3Q1MAD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAD1/entry", "sequence": { "sequence": "MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKDTNHNTPGSHYENSERGPVSSTSDSRTNCKNAVVNDSPEKEAWPSAPGSDPELVSECMDADSASSSESERPITIMASGSTGGENDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQASVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSPLGQMPNNQSINSKVGGASTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSNTGAWRVSTMNHPQIQAPSVVNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSSPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAVNSQSASWGNGANSGGSRRGWGTPAQNTGTNTPGVEWNKLPGNQHSSDSANGNGKKFTNGWKSTEEEDQGSAASQTNEQSSVWAKTGGTVESEGSTESTGRLEEKATGENQSRDRRKMDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACVDKTSPSSNDTSSVSGWGDPKPALRWGDSKGSSCQGGWEDDSAATGMVKSNQWGNCKEEKSAWNDSQKNKQGWGDGQKSNQGWSVSAGDNWGERSNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPNPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPMPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGSSRSDQQAQVHQLLPSAGTISNKEASSGSGWGEPWGETSTPATTVDNGTSAWGKPVDSGPSWGEPIAAASSTSTWGSSSVGPQTLNKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMDRSPYFDKNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPSLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRQQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQSLHQPAMKSFLENVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNAPLSSTAQSTAARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSSWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPSWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM", "length": 1766, "header": "tr|A0A3Q1MAD1-1|G3N258_BOVIN Computationally mapped isoform of Trinucleotide repeat containing adaptor 6A OS=Bos taurus OX=9913 GN=TNRC6A PE=3 SV=2 CANONICAL=G3N258-1" }, "locus": { "chromosome": "25", "start_pos": 22479022, "end_pos": 22384650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087097.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087097.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067169.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067169.2" } ] } }, { "isoform_ac": "A0A3Q1N978-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N978/entry", "sequence": { "sequence": "MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQQQQQQPQPQQQQPQQPQQPQPPPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLSSQSESSALTNQQPQNNGEVQISKNQSDTNHNTPGSHYENSERGPVSSTSDSRTNCKNAVVNDSPEKEAWPSAPGSDPELVSECMDADSASSSESERPITIMASGSTGGENDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQASVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSPLGQMPNNQSINSKVGGASTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSNTGAWRVSTMNHPQIQAPSVVNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSSPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAVNSQSASWGNGANSGGSRRGWGTPAQNTGTNTPGVEWNKLPGNQHSSDSANGNGKKFTNGWKSTEEEDQGSAASQTNEQSSVWAKTGGTVESEGSTESTGRLEEKATGENQSRDRRKMDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACVDKTSPSSNDTSSVSGWGDPKPALRWGDSKGSSCQGGWEDDSAATGMVKSNQWGNCKEEKSAWNDSQKNKQGWGDGQKSNQGWSVSAGDNWGERSNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPNPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPMPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGSSRSDQQAQVHQLLPSAGTISNKEASSGSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMDRSPYFDKNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPSLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRQQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQSLHQPAMKSFLENVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNAPLSSTAQSTAARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSSWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPSWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM", "length": 1840, "header": "tr|A0A3Q1N978-1|G3N258_BOVIN Computationally mapped isoform of Trinucleotide repeat containing adaptor 6A OS=Bos taurus OX=9913 GN=TNRC6A PE=3 SV=2 CANONICAL=G3N258-1" }, "locus": { "chromosome": "25", "start_pos": 22479022, "end_pos": 22384650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076904.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076904.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067682.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067682.2" } ] } }, { "isoform_ac": "F1MX25-1", "url": "https://www.uniprot.org/uniprotkb/F1MX25/entry", "sequence": { "sequence": "MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQQQQQQPQPQQQQPQQPQQPQPPPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLSSQSESSALTNQQPQNNGEVQISKNQSDTNHNTPGSHYENSERGPVSSTSDSRTNCKNAVVNDSPEKEAWPSAPGSDPELVSECMDADSASSSESERPITIMASGSTGGENDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQASVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSPLGQMPNNQSINSKVGGASTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSNTGAWRVSTMNHPQIQAPSVVNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSSPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAVNSQSASWGNGANSGGSRRGWGTPAQNTGTNTPGVEWNKLPGNQHSSDSANGNGKKFTNGWKSTEEEDQGSAASQTNEQSSVWAKTGGTVESEGSTESTGRLEEKATGENQSRDRRKMDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACVDKTSPSSNDTSSVSGWGDPKPALRWGDSKGSSCQGGWEDDSAATGMVKSNQWGNCKEEKSAWNDSQKNKQGWGDGQKSNQGWSVSAGDNWGERSNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPNPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPMPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGSSRSDQQAQVHQLLPSAGTISNKEASSGSGWGEPWGETSTPATTVDNGTSAWGKPVDSGPSWGEPIAAASSTSTWGSSSVGPQTLNKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMDRSPYFDKNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPSLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRQQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQSLHQPAMKSFLENVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNAPLSSTAQSTAARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSSWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPSWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM", "length": 1888, "header": "tr|F1MX25-1|G3N258_BOVIN Computationally mapped isoform of Trinucleotide repeat containing adaptor 6A OS=Bos taurus OX=9913 GN=TNRC6A PE=3 SV=3 CANONICAL=G3N258-1" }, "locus": { "chromosome": "25", "start_pos": 22479022, "end_pos": 22384650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023950.8", "url": "https://www.ensembl.org/id/ENSBTAT00000023950.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023950.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023950.7" } ] } }, { "isoform_ac": "G3N258-1", "url": "https://www.uniprot.org/uniprotkb/G3N258/entry", "sequence": { "sequence": 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"database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:541118", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541118", "resource": "KEGG Pathway" }, { "id": "R-BTA-426496", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-426496", "resource": "Reactome", "description": "Post-transcriptional silencing by small RNAs" }, { "id": "R-BTA-5578749", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5578749", "resource": "Reactome", "description": "Transcriptional regulation by small RNAs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": 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] }, { "id": "A0AAA9TIH3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RM69-1", "url": "https://www.uniprot.org/uniprotkb/F6RM69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MDQDYERRLLRQIVIQNENTMPCVAEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPERKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR", "length": 496, "header": "tr|A0A3Q1LP17-1|F6RM69_BOVIN Computationally mapped isoform of Fizzy-related protein homolog OS=Bos taurus OX=9913 GN=FZR1 PE=3 SV=1 CANONICAL=F6RM69-1" }, "locus": { "chromosome": "7", "start_pos": 20391500, "end_pos": 20385852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074490.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074490.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058619.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058619.2" } ] } }, { "isoform_ac": "A0AAA9TAC6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAC6/entry", "sequence": { "sequence": "MDQDYERRLLRQIVIQNENTMPCVAEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPERKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR", "length": 461, "header": "tr|A0AAA9TAC6-1|F6RM69_BOVIN Computationally mapped isoform of Fizzy-related protein homolog OS=Bos taurus OX=9913 GN=FZR1 PE=3 SV=1 CANONICAL=F6RM69-1" }, "locus": { "chromosome": "7", "start_pos": 20391500, "end_pos": 20385852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121405.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121405.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092944.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092944.1" } ] } }, { "isoform_ac": "A0AAA9TIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIH3/entry", "sequence": { "sequence": "MDQDYERRLLRQIVIQNENTMPCVAEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPERKGLFTVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR", "length": 404, "header": "tr|A0AAA9TIH3-1|F6RM69_BOVIN Computationally mapped isoform of Fizzy-related protein homolog OS=Bos taurus OX=9913 GN=FZR1 PE=3 SV=1 CANONICAL=F6RM69-1" }, "locus": { "chromosome": "7", "start_pos": 20391500, "end_pos": 20385852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111622.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111622.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096706.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096706.1" } ] } }, { "isoform_ac": "F6RM69-1", "url": "https://www.uniprot.org/uniprotkb/F6RM69/entry", "sequence": { "sequence": "MSHPGPLSTAGGAVPARLTMDQDYERRLLRQIVIQNENTMPCVAEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPERKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR", "length": 512, "header": "tr|F6RM69-1|F6RM69_BOVIN Isoform 1 of Fizzy-related protein homolog OS=Bos taurus OX=9913 GN=FZR1 PE=3 SV=2 CANONICAL=F6RM69-1" }, "locus": { "chromosome": "7", "start_pos": 20403618, "end_pos": 20385852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044471.3", "url": "https://www.ensembl.org/id/ENSBTAT00000044471.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041964.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041964.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" }, { "name": "negative regulation of cellular senescence", "id": "GO:2000773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000773", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin-protein transferase activator activity", "id": "GO:0097027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097027", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" }, { "name": "anaphase-promoting complex binding", "id": "GO:0010997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010997", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F6RM69", "url": "https://www.uniprot.org/uniprotkb/F6RM69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RM69-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 512, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RM69-F1.pdb", "url_external": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RV99-1", "uniprot_ac": "F6RV99", "uniprot_id": "F6RV99_BOVIN", "mass": { "chemical_mass": 42034.0, "monoisotopic_mass": 42034.0 }, "refseq": { "ac": "XP_010816224", "name": "transcription cofactor vestigial-like protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816224" }, "gene_names": [ { "name": "VGLL4", "type": "recommended", "evidence": [ { "id": "F6RV99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ] }, { "name": "VGLL4", "type": "synonym", "evidence": [ { "id": "XP_010816224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816224" } ] } ], "protein_names": [ { "name": "Vestigial like family member 4", "type": "synonym", "evidence": [ { "id": "F6RV99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RV99/entry#names_and_taxonomy" } ] }, { "name": "transcription cofactor vestigial-like protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010816224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816224" } ] } ], "function": [ { "annotation": "May act as a specific coactivator for the mammalian TEFs.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC2#function" }, { "database": "UniProtKB", "id": "ARBA00002229", "url": "https://www.uniprot.org/uniprotkb/ARBA00002229#function" }, { "database": "UniProtKB", "id": "A0AAA9T6E3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6E3#function" }, { "database": "UniProtKB", "id": "A0A3Q1MTH3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTH3#function" }, { "database": "UniProtKB", "id": "A0AAA9RZ10", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ10#function" }, { "database": "UniProtKB", "id": "A0AAA9S7U8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7U8#function" }, { "database": "UniProtKB", "id": "A0AAA9SPJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPJ2#function" }, { "database": "UniProtKB", "id": "A0AAA9TN24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN24#function" }, { "database": "UniProtKB", "id": "A0AAA9TLJ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLJ9#function" }, { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VGLL4", "url": "https://www.uniprot.org/uniprotkb/F6RV99", "locus": { "chromosome": "22", "start_pos": 55580751, "end_pos": 55776855, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018600", "url": "https://www.ensembl.org/id/ENSBTAG00000018600" } ] } } ], "crossref": [ { "id": "F6RV99", "url": "https://alphafold.ebi.ac.uk/entry/F6RV99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018600", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018600", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613904", "url": "https://www.ncbi.nlm.nih.gov/gene/613904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CPIAHSS", "url": "https://omabrowser.org/oma/group/CPIAHSS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPC2", "url": "https://www.orthodb.org/?gene=A0A3Q1LPC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MTH3", "url": "https://www.orthodb.org/?gene=A0A3Q1MTH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RV99", "url": "https://www.orthodb.org/?gene=F6RV99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17604", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17604", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17604:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17604:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15245", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15245", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010816224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTH3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ10", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ10-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7U8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7U8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6E3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6E3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLJ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TN24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TN24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RV99-1", "url": "https://www.uniprot.org/uniprotkb/F6RV99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDLGCLPHPSDLQASAVAGVRSWREIPCWGRRAQPGLQECVRQSACEFCIGSWEPRRLPSGPWLQHAGASIFAVTRGLQLQHVNSYCLTWDPVPRPGTEPQPPSFGAWSLSHWTTGEVPRSHLLKGEAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 392, "header": "tr|F6RV99-1|F6RV99_BOVIN Isoform 1 of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=2 CANONICAL=F6RV99-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC2/entry", "sequence": { "sequence": "METPLDVLSRAASLVHADDEKRPWLQHAGASIFAVTRGLQLQHVNSYCLTWDPVPRPGTEPQPPSFGAWSLSHWTTGEVPRSHLLKGEAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 352, "header": "tr|A0A3Q1LPC2-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=2 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55721894, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075088.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075088.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061918.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061918.2" } ] } }, { "isoform_ac": "A0A3Q1MTH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTH3/entry", "sequence": { "sequence": "METPLDVLSRAASLVHADDEKREAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 287, "header": "tr|A0A3Q1MTH3-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=2 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55721894, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073768.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073768.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073610.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073610.2" } ] } }, { "isoform_ac": "A0AAA9RZ10-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ10/entry", "sequence": { "sequence": "MAVVRLGSKGAAGTESASSVVVVVTTAVSTRLQPGMETPLDVLSRAASLVHADDEKREAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 322, "header": "tr|A0AAA9RZ10-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=1 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55734781, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111213.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111213.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078825.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078825.1" } ] } }, { "isoform_ac": "A0AAA9S7U8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7U8/entry", "sequence": { "sequence": "MRLKLPDCGGVKLMYNISLVRCSDEEAGWCHGKSSASEDGRRRKTALLKYLLLSCPCTSHKLHHLPCSNPARLQPGMETPLDVLSRAASLVHADDEKREAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 363, "header": "tr|A0AAA9S7U8-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=1 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55776855, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098214.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098214.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082105.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082105.1" } ] } }, { "isoform_ac": "A0AAA9SPJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPJ2/entry", "sequence": { "sequence": "MQASPQSKGEAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 274, "header": "tr|A0AAA9SPJ2-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=1 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55733671, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118510.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118510.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088213.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088213.1" } ] } }, { "isoform_ac": "A0AAA9T6E3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6E3/entry", "sequence": { "sequence": "MIKVRNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 207, "header": "tr|A0AAA9T6E3-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=1 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55597311, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097164.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097164.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091351.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091351.1" } ] } }, { "isoform_ac": "A0AAA9TLJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLJ9/entry", "sequence": { "sequence": "MLFMKMDLLNYQYLDNMNNNIGILCYEGPWLQHAGASIFAVTRGLQLQHVNSYCLTWDPVPRPGTEPQPPSFGAWSLSHWTTGEVPRSHLLKGEAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 358, "header": "tr|A0AAA9TLJ9-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=1 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55651417, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088853.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088853.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097817.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097817.1" } ] } }, { "isoform_ac": "A0AAA9TN24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN24/entry", "sequence": { "sequence": "MFIVSCLELMKSAHEPAGSSVGRLKSAEGSASQGCPGMGRVLGTSYLSSVSQSQCSHLNNGLQPGMETPLDVLSRAASLVHADDEKREAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 352, "header": "tr|A0AAA9TN24-1|F6RV99_BOVIN Computationally mapped isoform of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=1 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55733131, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102383.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102383.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099912.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099912.1" } ] } }, { "isoform_ac": "F6RV99-1", "url": "https://www.uniprot.org/uniprotkb/F6RV99/entry", "sequence": { "sequence": "MLDLGCLPHPSDLQASAVAGVRSWREIPCWGRRAQPGLQECVRQSACEFCIGSWEPRRLPSGPWLQHAGASIFAVTRGLQLQHVNSYCLTWDPVPRPGTEPQPPSFGAWSLSHWTTGEVPRSHLLKGEAALRGEPRLQTLPVASALTAHRTGPPPISPSKRKFSVDPGDDDLDCDGDHASKMSRIFAPHLNKTANGDCRKDPRERSRSPIERAVAPTMSLHSGPLYASLPSLSMEQPLALTKNSLDAGRPAGLSPTLAPVERQQNRPSVITCASASARNCNLSHCPVAHSGCAAGPASYRRTPSSTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 392, "header": "tr|F6RV99-1|F6RV99_BOVIN Isoform 1 of Vestigial like family member 4 OS=Bos taurus OX=9913 GN=VGLL4 PE=3 SV=2 CANONICAL=F6RV99-1" }, "locus": { "chromosome": "22", "start_pos": 55626498, "end_pos": 55581330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043987.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043987.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041513.5", "url": "https://www.ensembl.org/id/ENSBTAP00000041513.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 76, "start_aa": "Thr", "end_pos": 76, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480K188-1", "protein_name": "Vestigial like family member 4", "gene_name": "VGLL4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLFMKMDLLNYQYLDKMNNNIGILCYEGEAALRGEPRLQTLPVASALTGHRTGPPPISPSKRKFSVEPGDDDLDCEGDHASKMSRIFAPHLSKTANGDCRKDPRERSRSPIERAAAPTMSLHGSHLYTSLPSLSMEQPLALTKNSLDTSRPAGISPTLTPVERQQNRPSVITCASASTRNCNLSHCPVAHSGCAASPASFRRASSSATTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 295 }, "evidence": [ { "id": "F6RV99", "url": "https://omabrowser.org/oma/group/F6RV99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LFR6-1", "protein_name": "Transcription cofactor vestigial-like protein 4 isoform X1", "gene_name": "Vgll4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLFMKMDLLNYQYLDKMNNNIGVLCYEGEASLRGEPRMQTLPVASALSSHRTGPPPISPSKRKFSMEPGDKDLDCENDHVSKMSRIFSPHLNKTVNGDCRRDPRERSRSPIERAAAPAVSLHGGHLYASLPGLMEQPLALTKNSSDTGRSAVERQQNRPSVITCASAGARNCNLSHCPIAHSGCSAPASASYRRPPSATATCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDSASSSPESASRRGQPASPTAHMVSHSHSPSVVS", "length": 287 }, "evidence": [ { "id": "F6RV99", "url": "https://omabrowser.org/oma/group/F6RV99/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1NEM0-1", "protein_name": "Vestigial like family member 4", "gene_name": "VGLL4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLFMKMDLLNYQYLDKMNNNIGILCYEGEAALRGEPRMQSLPVSSALTNHRTGPPPISPNKRKLSMDQGDDEIDCENEHVSKMSRMFNPHLNKTANGDYRKEHRERSRSPIERAAAPTMSLHANHMYASIPSLTMDQPLALTKNSMDATRTVGITPTLTSVERQQNRPSVITCASANNRNCNLSHCPIAHSGCGSAVPAYRRPSSTTTACDPVVEEHFRRSLGKNYKEPEPVANSVSITGSVDDHFAKALGDTWLQIKAAKDGVSSSPESASRRGQSSPSSHMVNHNHSPSVVS", "length": 294 }, "evidence": [ { "id": "F6RV99", "url": "https://omabrowser.org/oma/group/F6RV99/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q14135-1", "protein_name": "Transcription cofactor vestigial-like protein 4", "gene_name": "VGLL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METPLDVLSRAASLVHADDEKREAALRGEPRIQTLPVASALSSHRTGPPPISPSKRKFSMEPGDEDLDCDNDHVSKMSRIFNPHLNKTANGDCRRDPRERSRSPIERAVAPTMSLHGSHLYTSLPSLGLEQPLALTKNSLDASRPAGLSPTLTPGERQQNRPSVITCASAGARNCNLSHCPIAHSGCAAPGPASYRRPPSAATTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS", "length": 290 }, "evidence": [ { "id": "F6RV99", "url": "https://omabrowser.org/oma/group/F6RV99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80V24-1", "protein_name": "Transcription cofactor vestigial-like protein 4", "gene_name": "Vgll4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFMKMDLLNYQYLDKMNNNIGVLCYEGEASLRGEPRMQTLPVASALSSHRTGPPPISPSKRKFSMEPGDKDLDCENDHVSKMSRIFSPHLNKTVNGDCRRDPRERSRSPIERAAAPAVSLHGGHLYASLPSLMEQPLALTKNSSDTGRSAVERQQNRPSVITCASAGARNCNLSHCPIAHSGCSAPGSASYRRPPSATATCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDSASSSPESASRRGQPASPTAHMVSHSHSPSVVS", "length": 287 }, "evidence": [ { "id": "F6RV99", "url": "https://omabrowser.org/oma/group/F6RV99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ], "pmid": "" }, { "name": "negative regulation of cardiac muscle cell proliferation", "id": "GO:0060044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060044", "evidence": [ { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RV99", "url": "https://www.uniprot.org/uniprotkb/F6RV99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RV99-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 392, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RV99-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RV99" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 76, 217 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N279-1", "uniprot_ac": "G3N279", "uniprot_id": "G3N279_BOVIN", "mass": { "chemical_mass": 100871.0, "monoisotopic_mass": 100871.0 }, "refseq": {}, "gene_names": [ { "name": "KCNQ5", "type": "recommended", "evidence": [ { "id": "G3N279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily Q member 5", "type": "synonym", "evidence": [ { "id": "G3N279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N279/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KCNQ5", "url": "https://www.uniprot.org/uniprotkb/G3N279", "locus": { "chromosome": "9", "start_pos": 12648826, "end_pos": 12003048, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007791", "url": "https://www.ensembl.org/id/ENSBTAG00000007791" } ] } } ], "crossref": [ { "id": "G3N279", "url": "https://alphafold.ebi.ac.uk/entry/G3N279", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007791", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007791", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613605", "url": "https://www.ncbi.nlm.nih.gov/gene/613605", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47735:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47735:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LPF3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3Q1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ML72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N279-1", "url": "https://www.uniprot.org/uniprotkb/G3N279-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRQHAGGEEGGAAGLWVRSGAPAAAAAAAAAGGGRTGGGMKDVESGRARALLNSAAAGGDGLLLLGTRAAALGGGGLRESRRGKQGARMSLLGKPLSYTSGQSCRRNVKYRRLQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSVATWKPHLKALHTCSPTKKEQGEASSSQVCSHKQKLFRIHTSWKQSQKLSFKERVRMASPRGQSVKSRQASLGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVVDADTALGTDDVYDDKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHEATDDLSMLGRVVKVEKQVQSIEAKLDCLLDIYQQVLRKGSAPALALAPFPSPPFECEQTSDYQSPGDGRDLSGPAPGGGLPRSASAGLARGLQLILAPSELGAQALYAFSPAPTPAPGSPGDGPAAPRGLAPPAAASAARPAAPATLQIPAALPVLGQLPHGPAGAPEALPELSARLAPAKDRLPARERALRQSLDLGGAALLSVRPAVPQDPGRSVSAQNLARSTEDLDVQLSGSESSGSRGSQEFYPKWRESKLFISDEEAASPEDTGTDALDAVPPAREPAPAPDSLRTGRSRSSQSSCPAAGGADALGRPHVRLK", "length": 936, "header": "tr|G3N279-1|G3N279_BOVIN Isoform 1 of Potassium voltage-gated channel subfamily Q member 5 OS=Bos taurus OX=9913 GN=KCNQ5 PE=4 SV=3 CANONICAL=G3N279-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF3/entry", "sequence": { "sequence": "MPRQHAGGEEGGAAGLWVRSGAPAAAAAAAAAGGGRTGGGMKDVESGRARALLNSAAAGGDGLLLLGTRAAALGGGGLRESRRGKQGARMSLLGKPLSYTSGQSCRRNVKYRRLQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSVATWKPHLKALHTCSPTKKEQGEASSSQKLSFKERVRMASPRGQSVKSRQASLGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVVDADTALGTDDVYDDKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHEATDDLSMLGRVVKVEKQVQSIEAKLDCLLDIYQQVLRKGSAPALALAPFPSPPFECEQTSDYQSPGDGRDLSGPAPGGGLPRSASAGLARGLQLILAPSELGAQALYAFSPAPTPAPGSPGDGPAAPRGLAPPAAASAARPAAPATLQIPAALPVLGQLPHGPAGAPEALPELSARLAPAKDRLPARERALRQSLDLGGAALLSVRPAVPQDPGRSVSAQNLARSTEDLDVQLSGSESSGSRGSQEFYPKWRESKLFISDEEAASPEDTGTDALDAVPPAREPAPAPDSLRTGRSRSSQSSCPAAGGADALGRPHVRLK", "length": 917, "header": "tr|A0A3Q1LPF3-1|G3N279_BOVIN Computationally mapped isoform of Potassium voltage-gated channel subfamily Q member 5 OS=Bos taurus OX=9913 GN=KCNQ5 PE=4 SV=2 CANONICAL=G3N279-1" }, "locus": { "chromosome": "9", "start_pos": 12648298, "end_pos": 12003247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071372.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071372.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061948.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061948.2" } ] } }, { "isoform_ac": "A0A3Q1M3Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3Q1/entry", "sequence": { "sequence": "MPRQHAGGEEGGAAGLWVRSGAPAAAAAAAAAGGGRTGGGMKDVESGRARALLNSAAAGGDGLLLLGTRAAALGGGGLRESRRGKQGARMSLLGKPLSYTSGQSCRRNVKYRRLQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSVATWKPHLKALHTCSPTKKEQGEASSRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHEATDDLSMLGRVVKVEKQVQSIEAKLDCLLDIYQQVLRKGSAPALALAPFPSPPFECEQTSDYQSPGDGRDLSGPAPGGGLPRSASAGLARGLQLILAPSELGAQALYAFSPAPTPAPGSPGDGPAAPRGLAPPAAASAARPAAPATLQIPAALPVLGQLPHGPAGAPEALPELSARLAPAKDRLPARERALRQSLDLGGAALLSVRPAVPQDPGRSVSAQNLARSTEDLDVQLSGSESSGSRGSQEFYPKWRESKLFISDEEAASPEDTGTDALDAVPPAREPAPAPDSLRTGRSRSSQSSCPAAGGADALGRPHVRLK", "length": 807, "header": "tr|A0A3Q1M3Q1-1|G3N279_BOVIN Computationally mapped isoform of Potassium voltage-gated channel subfamily Q member 5 OS=Bos taurus OX=9913 GN=KCNQ5 PE=4 SV=2 CANONICAL=G3N279-1" }, "locus": { "chromosome": "9", "start_pos": 12648298, "end_pos": 12003247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067006.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067006.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062827.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062827.2" } ] } }, { "isoform_ac": "A0A3Q1ML72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML72/entry", "sequence": { "sequence": "MPRQHAGGEEGGAAGLWVRSGAPAAAAAAAAAGGGRTGGGMKDVESGRARALLNSAAAGGDGLLLLGTRAAALGGGGLRESRRGKQGARMSLLGKPLSYTSGQSCRRNVKYRRLQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSVATWKPHLKALHTCSPTNQKLSFKERVRMASPRGQSVKSRQASLGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVVDADTALGTDDVYDDKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHEATDDLSMLGRVVKVEKQVQSIEAKLDCLLDIYQQVLRKGSAPALALAPFPSPPFECEQTSDYQSPGDGRDLSGPAPGGGLPRSASAGLARGLQLILAPSELGAQALYAFSPAPTPAPGSPGDGPAAPRGLAPPAAASAARPAAPATLQIPAALPVLGQLPHGPAGAPEALPELSARLAPAKDRLPARERALRQSLDLGGAALLSVRPAVPQDPGRSVSAQNLARSTEDLDVQLSGSESSGSRGSQEFYPKWRESKLFISDEEAASPEDTGTDALDAVPPAREPAPAPDSLRTGRSRSSQSSCPAAGGADALGRPHVRLK", "length": 908, "header": "tr|A0A3Q1ML72-1|G3N279_BOVIN Computationally mapped isoform of Potassium voltage-gated channel subfamily Q member 5 OS=Bos taurus OX=9913 GN=KCNQ5 PE=4 SV=2 CANONICAL=G3N279-1" }, "locus": { "chromosome": "9", "start_pos": 12648298, "end_pos": 12003247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082504.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082504.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071717.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071717.2" } ] } }, { "isoform_ac": "G3N279-1", "url": "https://www.uniprot.org/uniprotkb/G3N279/entry", "sequence": { "sequence": "MPRQHAGGEEGGAAGLWVRSGAPAAAAAAAAAGGGRTGGGMKDVESGRARALLNSAAAGGDGLLLLGTRAAALGGGGLRESRRGKQGARMSLLGKPLSYTSGQSCRRNVKYRRLQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSVATWKPHLKALHTCSPTKKEQGEASSSQVCSHKQKLFRIHTSWKQSQKLSFKERVRMASPRGQSVKSRQASLGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVVDADTALGTDDVYDDKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHEATDDLSMLGRVVKVEKQVQSIEAKLDCLLDIYQQVLRKGSAPALALAPFPSPPFECEQTSDYQSPGDGRDLSGPAPGGGLPRSASAGLARGLQLILAPSELGAQALYAFSPAPTPAPGSPGDGPAAPRGLAPPAAASAARPAAPATLQIPAALPVLGQLPHGPAGAPEALPELSARLAPAKDRLPARERALRQSLDLGGAALLSVRPAVPQDPGRSVSAQNLARSTEDLDVQLSGSESSGSRGSQEFYPKWRESKLFISDEEAASPEDTGTDALDAVPPAREPAPAPDSLRTGRSRSSQSSCPAAGGADALGRPHVRLK", "length": 936, "header": "tr|G3N279-1|G3N279_BOVIN Isoform 1 of Potassium voltage-gated channel subfamily Q member 5 OS=Bos taurus OX=9913 GN=KCNQ5 PE=4 SV=3 CANONICAL=G3N279-1" }, "locus": { "chromosome": "9", "start_pos": 12648298, "end_pos": 12003247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065391.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065391.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055988.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055988.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 731, "start_aa": "Thr", "end_pos": 731, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr731", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ], "pmid": "" }, { "name": "clathrin coat", "id": "GO:0030118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030118", "evidence": [ { "database": "UniProtKB", "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "G3N279", "url": "https://www.uniprot.org/uniprotkb/G3N279" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N279-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 936, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N279-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N279" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N279" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 358, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N279" }, { "id": "PF03520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel voltage dependent KCNQ C-terminal", "eco_id": "ECO_0000259", "start_pos": 469, "end_pos": 656, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 731 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "G3X7M7-1", "uniprot_ac": "G3X7M7", "uniprot_id": "G3X7M7_BOVIN", "mass": { "chemical_mass": 92547.0, "monoisotopic_mass": 92547.0 }, "refseq": {}, "gene_names": [ { "name": "LOC787287", "type": "recommended", "evidence": [ { "id": "G3X7M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ] } ], "protein_names": [ { "name": "Zinc finger protein 471", "type": "synonym", "evidence": [ { "id": "G3X7M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7M7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7#function" } ] } ], 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"categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF107", "database": "PANTHER", "categories": [ "Protein 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"MLRRSITLAALCMLIYGIVYCQALPSQDSAVLQERSQEKKVKMTVQLVKAIPQDLVTFKDVAIDFSQEEWEWLSPAQRSLYRSMMLENYQSLVSLGLCISKPYVISLLEQGKEPWMVLENEMRSPFPDWESIHETQELALKQCVCDDTLMERIASYEQECPIFGENWKCEDLFERQLLSQETFIRQERSALKENLTVEIDHRYNKPEKFVPLHSLEENIYDNHKSDEKNFSRNSMVLKHKKVYAGKKLFKCNECEKTFTQSSSLTVHQRIHTGEKPYECKDCGKAFNQSQHLVQHHRIHTGEKLFECKECRKAFSQNVHLIQHQRIHTGEKPYKCKECRKAFSQPAHLAQHQRIHTGEKPYKCKECGKAFSDGSSFARHQRCHTGKRPYECIECGKAFRQNTSLIRHWRYYHTGEKPFDCIDCGKAFSDHIGLIQHRRIHTGEKPYKCNVCGKTFSYGSSLTVHQRIHTGEKPYECDICGKAFSHHASLTQHQRVHSGEKPYQCGECGKAFRQSIHLASHLRIHTGEKPYECKECGKAFSISSQLATHQRIHTGEKPYECKECGKAFNQRAHLAQHHKIHTGEKPYDCTECGKAFSQATRLIQHQRVHTGEKPYECTECGKAFSDSSSRAQHLRLHTGQKPYACVECEKAFRTKSSLTCHQRCHTGEKPYKCSACGKAFSHRQSLTVHQRIHSGEKPYQCKECRKTFSQIGHLNLHRRIHTGERSYECKECGEVFRQSAHLAHHHKIHATESSQALSSSPPPASSSPRDMSAEYFWNSSTSFHPHCPNPKRSHLIWTIPIV", "length": 801, "header": "tr|G3X7M7-1|G3X7M7_BOVIN Isoform 1 of Zinc finger protein 471 OS=Bos taurus OX=9913 GN=LOC787287 PE=3 SV=3 CANONICAL=G3X7M7-1" }, "isoforms": [ { "isoform_ac": 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protein 471 OS=Bos taurus OX=9913 GN=LOC787287 PE=3 SV=1 CANONICAL=G3X7M7-1" }, "locus": { "chromosome": "18", "start_pos": 63819763, "end_pos": 63805042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072347.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072347.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059304.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059304.2" } ] } }, { "isoform_ac": "G3X7M7-1", "url": "https://www.uniprot.org/uniprotkb/G3X7M7/entry", "sequence": { "sequence": "MLRRSITLAALCMLIYGIVYCQALPSQDSAVLQERSQEKKVKMTVQLVKAIPQDLVTFKDVAIDFSQEEWEWLSPAQRSLYRSMMLENYQSLVSLGLCISKPYVISLLEQGKEPWMVLENEMRSPFPDWESIHETQELALKQCVCDDTLMERIASYEQECPIFGENWKCEDLFERQLLSQETFIRQERSALKENLTVEIDHRYNKPEKFVPLHSLEENIYDNHKSDEKNFSRNSMVLKHKKVYAGKKLFKCNECEKTFTQSSSLTVHQRIHTGEKPYECKDCGKAFNQSQHLVQHHRIHTGEKLFECKECRKAFSQNVHLIQHQRIHTGEKPYKCKECRKAFSQPAHLAQHQRIHTGEKPYKCKECGKAFSDGSSFARHQRCHTGKRPYECIECGKAFRQNTSLIRHWRYYHTGEKPFDCIDCGKAFSDHIGLIQHRRIHTGEKPYKCNVCGKTFSYGSSLTVHQRIHTGEKPYECDICGKAFSHHASLTQHQRVHSGEKPYQCGECGKAFRQSIHLASHLRIHTGEKPYECKECGKAFSISSQLATHQRIHTGEKPYECKECGKAFNQRAHLAQHHKIHTGEKPYDCTECGKAFSQATRLIQHQRVHTGEKPYECTECGKAFSDSSSRAQHLRLHTGQKPYACVECEKAFRTKSSLTCHQRCHTGEKPYKCSACGKAFSHRQSLTVHQRIHSGEKPYQCKECRKTFSQIGHLNLHRRIHTGERSYECKECGEVFRQSAHLAHHHKIHATESSQALSSSPPPASSSPRDMSAEYFWNSSTSFHPHCPNPKRSHLIWTIPIV", "length": 801, "header": "tr|G3X7M7-1|G3X7M7_BOVIN Isoform 1 of Zinc finger protein 471 OS=Bos taurus OX=9913 GN=LOC787287 PE=3 SV=3 CANONICAL=G3X7M7-1" }, "locus": { "chromosome": "18", "start_pos": 63819763, "end_pos": 63808501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038858.7", "url": "https://www.ensembl.org/id/ENSBTAT00000038858.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038665.6", "url": "https://www.ensembl.org/id/ENSBTAP00000038665.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G3X7M7", "url": "https://www.uniprot.org/uniprotkb/G3X7M7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"ENSBTAG00000046110", "url": "https://www.ensembl.org/id/ENSBTAG00000046110" } ] } } ], "crossref": [ { "id": "G3MXT9", "url": "https://alphafold.ebi.ac.uk/entry/G3MXT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046110", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MXT9", "url": "https://www.orthodb.org/?gene=G3MXT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21353:SF7", "url": 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"sequence": "MSHTEKKKKIRNRAKKTCEWAWRMGLLKLRRSRGSPSHSASLRERSRARPARPPAPWTSEQVGARRPRPRPPPPPGSRQIRFPSFPRGVPSRGRAGEPGAAPACGARAGAGGHGPGALERGRAGTRHSWSPLGGAGRWPKRGGQPGRPTDLGGGHLEPGEAGSRDRGGPSPAPKSGERVRGRSGSAGGDGARGGGGGRERKRAGGRGARGSPRPGRREARGGRHLGPRRSPSPARREGRAGRRAGERRAEGRAAPGWSGPGRGSRGFLAARRAAGATMLPVAGEPAAATPLCAPDALPRLPPPRGRVPASSCARPGPPLWGDSWGMLACLCTVLWQLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGVETLPKATVNLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWAPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPATAVTLHLEARGF", "length": 540, "header": "tr|G3MXT9-1|G3MXT9_BOVIN Isoform 1 of Cardiotrophin-like cytokine factor 1 OS=Bos taurus OX=9913 GN=CLCF1 PE=3 SV=3 CANONICAL=G3MXT9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTH7/entry", "sequence": { "sequence": "MSHTEKKKKIRNRAKKTCEWAWRMGLLKLRRSRGSPSHSASLRERSRARPARPPAPWTSEQVGARRPRPRPPPPPGSRQIRFPSFPRGVPSRGRAGEPGAAPACGARAGAGGHGPGALERGRAGTRHSWSPLGGAGRWPKRGGQPGRPTDLGGGHLEPGEAGSRDRGGPSPAPKSGERVRGRSGSAGGDGARGGGGGRERKRAGGRGARGSPRPGRREARGGRHLGPRRSPSPARREGRAGRRAGERRAEGRAAPGWSGPGRGSRGFLAARRAAGATMLPVAGEPAAGDSWGMLACLCTVLWQLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGVETLPKATVNLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWAPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPATAVTLHLEARGF", "length": 507, "header": "tr|A0A3Q1LTH7-1|G3MXT9_BOVIN Computationally mapped isoform of Cardiotrophin-like cytokine factor 1 OS=Bos taurus OX=9913 GN=CLCF1 PE=3 SV=2 CANONICAL=G3MXT9-1" }, "locus": { "chromosome": "29", "start_pos": 45273993, "end_pos": 45265240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084250.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084250.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060381.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060381.2" } ] } }, { "isoform_ac": "G3MXT9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXT9/entry", "sequence": { "sequence": "MSHTEKKKKIRNRAKKTCEWAWRMGLLKLRRSRGSPSHSASLRERSRARPARPPAPWTSEQVGARRPRPRPPPPPGSRQIRFPSFPRGVPSRGRAGEPGAAPACGARAGAGGHGPGALERGRAGTRHSWSPLGGAGRWPKRGGQPGRPTDLGGGHLEPGEAGSRDRGGPSPAPKSGERVRGRSGSAGGDGARGGGGGRERKRAGGRGARGSPRPGRREARGGRHLGPRRSPSPARREGRAGRRAGERRAEGRAAPGWSGPGRGSRGFLAARRAAGATMLPVAGEPAAATPLCAPDALPRLPPPRGRVPASSCARPGPPLWGDSWGMLACLCTVLWQLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGVETLPKATVNLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWAPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPATAVTLHLEARGF", "length": 540, "header": "tr|G3MXT9-1|G3MXT9_BOVIN Isoform 1 of Cardiotrophin-like cytokine factor 1 OS=Bos taurus OX=9913 GN=CLCF1 PE=3 SV=3 CANONICAL=G3MXT9-1" }, "locus": { "chromosome": "29", "start_pos": 45273993, "end_pos": 45265240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064317.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064317.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054359.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054359.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6788467", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788467", "resource": "Reactome", "description": "IL-6-type cytokine receptor ligand interactions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" }, { "name": "CRLF-CLCF1 complex", "id": "GO:0097058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097058", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" }, { "name": "CNTFR-CLCF1 complex", "id": "GO:0097059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097059", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of B cell proliferation", "id": "GO:0030890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030890", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via STAT", "id": "GO:0097696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097696", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "G3MXT9", "url": "https://www.uniprot.org/uniprotkb/G3MXT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXT9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 540, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXT9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXT9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7I7-1", "uniprot_ac": "G3X7I7", "uniprot_id": "G3X7I7_BOVIN", "mass": { "chemical_mass": 91321.0, "monoisotopic_mass": 91321.0 }, "refseq": { "ac": "XP_059739427", "name": "zinc finger protein 711 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739427" }, "gene_names": [ { "name": "ZNF711", "type": "recommended", "evidence": [ { "id": "G3X7I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ] }, { "name": "ZNF711", "type": "synonym", "evidence": [ { "id": "XP_059739427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739427" } ] } ], "protein_names": [ { "name": "Zinc finger protein 711", "type": "recommended", "evidence": [ { "id": "G3X7I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7I7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 711 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_059739427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739427" } ] } ], "function": [ { "annotation": "Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activated expression of genes involved in neuron development, such as KDM5C. May compete with transcription factor ARX for activation of expression of KDM5C.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUA0#function" }, { "database": "UniProtKB", "id": "ARBA00059295", "url": "https://www.uniprot.org/uniprotkb/ARBA00059295#function" }, { "database": "UniProtKB", "id": "A0AAA9T138", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T138#function" }, { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF711", "url": "https://www.uniprot.org/uniprotkb/G3X7I7", "locus": { "chromosome": "X", "start_pos": 66972303, "end_pos": 67002748, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002668", "url": "https://www.ensembl.org/id/ENSBTAG00000002668" } ] } } ], "crossref": [ { "id": "G3X7I7", "url": "https://alphafold.ebi.ac.uk/entry/G3X7I7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002668", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002668", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "526026", "url": "https://www.ncbi.nlm.nih.gov/gene/526026", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526026", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526026", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEDDISC", "url": "https://omabrowser.org/oma/group/QEDDISC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7I7", "url": "https://www.orthodb.org/?gene=G3X7I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059739427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739427", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T138", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T138-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T138-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7I7-1", "url": "https://www.uniprot.org/uniprotkb/G3X7I7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPGGGSLGLHTSDSRMAHTMIMQDFVAGMTGTAHIDGDHIVVSVPEAVLVSDVVTDGGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVTGPDGHLEHVVQDCVSGVDSPTVVSEEVLVTNSDTETVIQAAGGVPGSTVTIKTEDDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKISSDGSQEDVKEDGFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYTNGHSVAGVLDQSRMQREKMVYMAVKDSSQEEDDISCAEIADEVYMEVIVGEEEGIFPETQLKDFDVNKTIVPIVWAVVYGDERRVSRRYEDCQSSGNTLDSTLENRSSTAAQYLQICDSINTNKVLKQKTKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKNFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHSGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRHHKEALI", "length": 806, "header": "tr|G3X7I7-1|G3X7I7_BOVIN Isoform 1 of Zinc finger protein 711 OS=Bos taurus OX=9913 GN=ZNF711 PE=3 SV=2 CANONICAL=G3X7I7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUA0/entry", "sequence": { "sequence": "MDPGGGSLGLHTSDSRMAHTMIMQDFVAGMTGTAHIDGDHIVVSVPEAVLVSDVVTDGGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVTGPDGHLEHVVQDCVSGVDSPTVVSEEVLVTNSDTETVIQAAGGVPGSTVTIKTEDDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKISSDGSQEDVKEDGFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYTNGHSVAGVLDQSRMQREKMVYMAVKDSSQEEDDIRDERRVSRRYEDCQSSGNTLDSTLENRSSTAAQYLQICDSINTNKVLKQKTKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKNFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHSGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRHHKEALI", "length": 761, "header": "tr|A0A3Q1LUA0-1|G3X7I7_BOVIN Computationally mapped isoform of Zinc finger protein 711 OS=Bos taurus OX=9913 GN=ZNF711 PE=3 SV=1 CANONICAL=G3X7I7-1" }, "locus": { "chromosome": "X", "start_pos": 66999357, "end_pos": 66973779, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074467.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074467.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064092.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064092.1" } ] } }, { "isoform_ac": "A0AAA9T138-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T138/entry", "sequence": { "sequence": "MDPGGGSLGLHTSDSRMAHTMIMQDFVSDVVTDGGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVTGPDGHLEHVVQDCVSGVDSPTVVSEEVLVTNSDTETVIQAAGGVPGSTVTIKTEDDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKISSDGSQEDVKEDGFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYTNGHSVAGVLDQSRMQREKMVYMAVKDSSQEEDDIRDERRVSRRYEDCQSSGNTLDSTLENRSSTAAQYLQICDSINTNKVLKQKTKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKNFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHSGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRHHKEALI", "length": 737, "header": "tr|A0AAA9T138-1|G3X7I7_BOVIN Computationally mapped isoform of Zinc finger protein 711 OS=Bos taurus OX=9913 GN=ZNF711 PE=3 SV=1 CANONICAL=G3X7I7-1" }, "locus": { "chromosome": "X", "start_pos": 66999357, "end_pos": 66973779, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090342.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090342.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090080.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090080.1" } ] } }, { "isoform_ac": "G3X7I7-1", "url": "https://www.uniprot.org/uniprotkb/G3X7I7/entry", "sequence": { "sequence": "MDPGGGSLGLHTSDSRMAHTMIMQDFVAGMTGTAHIDGDHIVVSVPEAVLVSDVVTDGGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVTGPDGHLEHVVQDCVSGVDSPTVVSEEVLVTNSDTETVIQAAGGVPGSTVTIKTEDDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKISSDGSQEDVKEDGFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYTNGHSVAGVLDQSRMQREKMVYMAVKDSSQEEDDISCAEIADEVYMEVIVGEEEGIFPETQLKDFDVNKTIVPIVWAVVYGDERRVSRRYEDCQSSGNTLDSTLENRSSTAAQYLQICDSINTNKVLKQKTKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKNFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHSGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRHHKEALI", "length": 806, "header": "tr|G3X7I7-1|G3X7I7_BOVIN Isoform 1 of Zinc finger protein 711 OS=Bos taurus OX=9913 GN=ZNF711 PE=3 SV=2 CANONICAL=G3X7I7-1" }, "locus": { "chromosome": "X", "start_pos": 66999357, "end_pos": 66973779, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031586.6", "url": "https://www.ensembl.org/id/ENSBTAT00000031586.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031537.5", "url": "https://www.ensembl.org/id/ENSBTAP00000031537.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:526026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526026", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ANX9-1", "protein_name": "Zinc finger protein 711", "gene_name": "Znf711", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESGGGSLGLHTSDARMAHTMIMQDFVAGMAGTAHIDGDHIVVSVPEAVLVSDVVTDDGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVSGPDGHLEHVVQDCVSGVDSPTMVSEEVLVTNSDTETVIQAGGGVPGSTVTIKTEEDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKIASDGSQEDVKEDAFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYSSGHSVAGVLDQSRMQREKMVYMAVKDSSQEQDDIRDERRVSRRYEECQAPGNTFDSALENRNTTAAQYLQICDSMNTNKVLKQKIKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKSFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCAFRCADQSNLKTHIKSKHGSNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHTGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKKQHIMRHHKETLM", "length": 761 }, "evidence": [ { "id": "G3X7I7", "url": "https://omabrowser.org/oma/group/G3X7I7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZHB2-1", "protein_name": "Zinc finger protein 711", "gene_name": "Zfp711", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSGGGSLGLHTSDARMAHTMIMQDFVAGMAGTAHIDGDHIVVSVPEAVLVSDVVTDDGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADIVSGPDGHLEHVVQDCVSGVDSPTMVSEEVLVTNSDTETVIQATGGVPGSTVTIKTEDDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKIGSDGSQEDVKEDGFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYTSGHSVAGVLDQSRMQREKMVYMAVKDSSQEEDDISYAEISDELYMEVIIGEEEGNLLEIQLEDSDVNKTVSPVVYPASYDERRVSRRYEDCQATGNTFDSALENRSTTAAQYLQICDSMNTNKVLKQKIKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKSFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYKCEHCPQSFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHTGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRHHKETLI", "length": 805 }, "evidence": [ { "id": "G3X7I7", "url": "https://omabrowser.org/oma/group/G3X7I7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y462-1", "protein_name": "Zinc finger protein 711", "gene_name": "ZNF711", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSGGGSLGLHTPDSRMAHTMIMQDFVAGMAGTAHIDGDHIVVSVPEAVLVSDVVTDDGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVTGPNGHLEHVVQDCVSGVDSPTMVSEEVLVTNSDTETVIQAAGGVPGSTVTIKTEDDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKIGSDGSQEDAKEDGFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYTSGHSVAGVLDQSRMQREKMVYMAVKDSSQEEDDIRDERRVSRRYEDCQASGNTLDSALESRSSTAAQYLQICDGINTNKVLKQKAKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKNFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCIFRCADQSNLKTHIKSKHGNNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQPLKCKRCKRGFRQQNELKKHMKTHTGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRHHKEALM", "length": 761 }, "evidence": [ { "id": "G3X7I7", "url": "https://omabrowser.org/oma/group/G3X7I7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "G3X7I7", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7I7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 806, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7I7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7I7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7I7" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 428, "end_pos": 458, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 646, "end_pos": 648 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"MESGPASMSSSSSYLYQEQQQQQPQQTESIPQTPNYILKYTLKGHLKSISSVKFSPDGKWLASASADKTIKIWGAYDGKFERTLEGHKEGISDIAWSQDSKLICSASDDKTIKIWDVESGKMVKTLKGHKEYVFGVSFNPQSNLIVSGSFDENVRIWDVNTGECTKMISAHSDPVTGVHFNRDGTLVVSGSYDGTVRIWDTTTGQLLNTISTEDGKEVSFVKFSPNGKFVLAGTLDNTLRLWSYNNNKKCLKTYTGHKNEKYCIFSTFSVTCGKWIVTGSEDNLIYIYNLQTREIVQTLAGHEDVVLTVACHPTENIIASGALEKDRSVKIWKHM", "length": 335 }, "evidence": [ { "id": "G3N3E5", "url": "https://omabrowser.org/oma/group/G3N3E5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9M2Z2-1", "protein_name": "COMPASS-like H3K4 histone methylase component WDR5A", "gene_name": "WDR5A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEEIPATASFTPYVHSQTLTSHNRAVSSVKFSSDGRLLASASADKTIRTYTINTINDPIAEPVQEFTGHENGISDVAFSSDARFIVSASDDKTLKLWDVETGSLIKTLIGHTNYAFCVNFNPQSNMIVSGSFDETVRIWDVTTGKCLKVLPAHSDPVTAVDFNRDGSLIVSSSYDGLCRIWDSGTGHCVKTLIDDENPPVSFVRFSPNGKFILVGTLDNTLRLWNISSAKFLKTYTGHVNAQYCISSAFSVTNGKRIVSGSEDNCVHMWELNSKKLLQKLEGHTETVMNVACHPTENLIASGSLDKTVRIWTQKKE", "length": 317 }, "evidence": [ { "id": "G3N3E5", "url": "https://omabrowser.org/oma/group/G3N3E5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V3J8-1", "protein_name": "Protein will die slowly", "gene_name": "wds", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVPIGAVHGGHPGVVHPPQQPLPTAPSGPNSLQPNSVGQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSDT", "length": 361 }, "evidence": [ { "id": "G3N3E5", "url": "https://omabrowser.org/oma/group/G3N3E5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "MLL3/4 complex", "id": "GO:0044666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044666", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "MLL1 complex", "id": "GO:0071339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071339", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "histone H3Q5ser reader activity", "id": "GO:0140004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140004", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "histone H3K4me1 reader activity", "id": "GO:0140109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140109", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "G3N3E5", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3E5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 334, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3E5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3E5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3E5" }, { "id": "PF25175", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25175" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WDR5-like beta-propeller", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 331, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 18 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E560-1", "uniprot_ac": "G5E560", "uniprot_id": "G5E560_BOVIN", "mass": { "chemical_mass": 109497.0, "monoisotopic_mass": 109497.0 }, "refseq": {}, "gene_names": [ { "name": "PSD", "type": "recommended", "evidence": [ { "id": "G5E560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ] } ], "protein_names": [ { "name": "Pleckstrin and Sec7 domain containing", "type": "synonym", "evidence": [ { "id": "G5E560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E560/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PSD", "url": "https://www.uniprot.org/uniprotkb/G5E560", "locus": { "chromosome": "26", "start_pos": 23026186, "end_pos": 23041793, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003580", "url": "https://www.ensembl.org/id/ENSBTAG00000003580" } ] } } ], "crossref": [ { "id": "G5E560", "url": "https://alphafold.ebi.ac.uk/entry/G5E560", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003580", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003580", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13295", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13295", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AKWEFFF", "url": "https://omabrowser.org/oma/group/AKWEFFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M1L3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E560-1", "url": "https://www.uniprot.org/uniprotkb/G5E560-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRSRELGRVTAPCTPLRGPPSPRIAPSPWAPSSPTGQPPPGARSSVVIFRFVEKASVRPLNGLPAPGGLSRSWDLGGVSPPRPTPALGPGSHQKLRLEASTSDPLPAGGGSARPGTQGLLQGPPTQPQVGADGLYSSLPNGLGGPSEHLATLFRGPADTGLLNQGDIWSSPREVSSHAQRIARAKWEFFYGSLDPPSSGAKPPEQAPPSPPGVGSGQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLTEREEADSAIESQPSSEGLPGTARPPAPRPGPCLGPHPSLGSGNEDEDEAGGEEDVDDEVFEASEGARPGTRMPHSGPLKSPLPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQRGEEEEAEAGAKQTPGRDPPSPCHSEDSFGLGAAPLGSEPPLNQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPGALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNEGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRVSGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKNFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRATQLTKKARGKEAEEQRQKEAYLEFEKSRYGTYAALLRVKLKAGSEELDAVEAAVAQAGGTEDGLPPPHSSPSLPANTSSQPRAQCSDSEARAGAGSGRWKP", "length": 1026, "header": "tr|G5E560-1|G5E560_BOVIN Isoform 1 of Pleckstrin and Sec7 domain containing OS=Bos taurus OX=9913 GN=PSD PE=4 SV=2 CANONICAL=G5E560-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1L3/entry", "sequence": { "sequence": "MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRSRELGRVTAPCTPLRGPPSPRIAPSPWAPSSPTGQPPPGARSSVVIFRFVEKASVRPLNGLPAPGGLSRSWDLGGVSPPRPTPALGPGSHQKLRLEASTSDPLPAGGGSARPGTQGLLQGPPTQPQVGADGLYSSLPNGLGGPSEHLATLFRGPADTGLLNQGDIWSSPREVSSHAQRIARAKWEFFYGSLDPPSSGAKPPEQAPPSPPGVGSGQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLTEREEADSAIESQPSSEGLPGTARPPAPRPGPCLGPHPSLGSGNEDEDEAGGEEDVDDEVFEASEGARPGTRMPHSGPLKSPLPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQRGEEEEAEAGAKQTPGRDPPSPCHSEDSFGLGAAPLGSEPPLNQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPGALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNEGGDFPRELLKVGGWDEEELRRSLSELADPNPKVIKRVSGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKNFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRATQLTKKARGKEAEEQRQKEAYLEFEKSRYGTYAALLRVKLKAGSEELDAVEAAVAQAGGTEDGLPPPHSSPSLPANTSSQPRAQCSDSEARAGAGSGRWKP", "length": 1015, "header": "tr|A0A3Q1M1L3-1|G5E560_BOVIN Computationally mapped isoform of Pleckstrin and Sec7 domain containing OS=Bos taurus OX=9913 GN=PSD PE=4 SV=1 CANONICAL=G5E560-1" }, "locus": { "chromosome": "26", "start_pos": 23040116, "end_pos": 23026768, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067574.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067574.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061940.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061940.1" } ] } }, { "isoform_ac": "G5E560-1", "url": "https://www.uniprot.org/uniprotkb/G5E560/entry", "sequence": { "sequence": "MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRSRELGRVTAPCTPLRGPPSPRIAPSPWAPSSPTGQPPPGARSSVVIFRFVEKASVRPLNGLPAPGGLSRSWDLGGVSPPRPTPALGPGSHQKLRLEASTSDPLPAGGGSARPGTQGLLQGPPTQPQVGADGLYSSLPNGLGGPSEHLATLFRGPADTGLLNQGDIWSSPREVSSHAQRIARAKWEFFYGSLDPPSSGAKPPEQAPPSPPGVGSGQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLTEREEADSAIESQPSSEGLPGTARPPAPRPGPCLGPHPSLGSGNEDEDEAGGEEDVDDEVFEASEGARPGTRMPHSGPLKSPLPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQRGEEEEAEAGAKQTPGRDPPSPCHSEDSFGLGAAPLGSEPPLNQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPGALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNEGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRVSGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKNFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRATQLTKKARGKEAEEQRQKEAYLEFEKSRYGTYAALLRVKLKAGSEELDAVEAAVAQAGGTEDGLPPPHSSPSLPANTSSQPRAQCSDSEARAGAGSGRWKP", "length": 1026, "header": "tr|G5E560-1|G5E560_BOVIN Isoform 1 of Pleckstrin and Sec7 domain containing OS=Bos taurus OX=9913 GN=PSD PE=4 SV=2 CANONICAL=G5E560-1" }, "locus": { "chromosome": "26", "start_pos": 23040116, "end_pos": 23026768, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004659.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004659.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004659.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004659.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 138, "start_aa": "Thr", "end_pos": 138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr138", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 437, "start_aa": "Thr", "end_pos": 437, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr437", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AIK9-1", "protein_name": "Pleckstrin and Sec7 domain containing", "gene_name": "PSD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGRELGRVTAPCTPLRGPPSPRVALSPWAPSSPTGQPPAGARSSVVIFRFVEKASVRPLNGLPAPGGLSRSWDLGGVSPPRPTAALGPGSNRKLRLEASTSDPLPAGGGSALPGSQGLLHGPPAQPQGGADGLYSSLPNGLGGPSEHLATLFRGPADTGLLNQGGTWSSPREVSSHAQRIARAKWEFFYGSLDPPSSGAKPPEQAPPSPPGVGSGQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLAEREEADSAIDSQPSSEGPAGTTRPPAPRPSPCRGPCPSLGSGNEEEEEAGGEEDVDDEVFEASEGARPGTQMPHSGPLKSPVPFLLGTSPSADGPDSFSCVFEAILESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGLWTQRGEEEEAEAGAKQAPGREPPSPCRSEDSFGLGAAPLGSEQPLSQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPGALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNEGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRVSGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAQLGKKARGKEAEEQRQKEAYLEFEKSRYGTYAALLRVKLKAGSEELDAVEAALAQAGSTEDGLPLLIPVPPCSPTPPASPGLSVLAQSLGQGPAVGGGSPELGVGVRVGGAVSTWHLHDMALLEPGPASGHL", "length": 1058 }, "evidence": [ { "id": "G5E560", "url": "https://omabrowser.org/oma/group/G5E560/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5PKW4-1", "protein_name": "PH and SEC7 domain-containing protein 1", "gene_name": "PSD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRGRELGRVTAPCTPLRGPPSPRVAPSPWAPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPAPGGLSRSWDLGGVSPPRPTPALGPGSNRKLRLEASTSDPLPARGGSALPGSRNLVHGPPAPPQVGADGLYSSLPNGLGGPPERLATLFGGPADTGFLNQGDTWSSPREVSSHAQRIARAKWEFFYGSLDPPSSGAKPPEQAPPSPPGVGSRQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLAEREEADSAIESQPSSEGPPGTAYPPAPRPGPLPGPHPSLGSGNEDEDDDEAGGEEDVDDEVFEASEGARPGSRMPLKSPVPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQRGEEEEAEARAKLAPGREPPSPCHSEDSLGLGAAPLGSEPPLSQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRISGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYKPGKALSETELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAQLGKKGRGKEAEEQRQKEAYLEFEKSRYSTYAALLRVKLKAGSEELDAVEAALAQAGSTEDGLPPSHSSPSLQPKPSSQPRAQRHSSEPRPGAGSGRRKP", "length": 1024 }, "evidence": [ { "id": "G5E560", "url": "https://omabrowser.org/oma/group/G5E560/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5DTT2-1", "protein_name": "PH and SEC7 domain-containing protein 1", "gene_name": "Psd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLIRRVVGPGPRGRDLGRVTAPCTPLRAPPSPHIAPSPWGPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPASGGLSRSWDLGGISAPRPTPALGPGCNRKLRLEASTSDPLPAGGGSVLPGSRDPSRGPLVPPQIGADGLYSSLPNGLGGTPEHLAMHFRGPADTGFLNQGDTWSSPREVSSHAQRIARAKWEFFYGSLDAPSSGAKPPEQVLPSRGVGSKQGSGVAVGRAAKYSETDLDKVPLRCYRETDIDEVLAEREEADSAIESQPSSEGPHGTAQPPASRPSPCPGPSSSLGSGNEDDEAGGEEDVDDEVFEASEGARPGDHMPHSGLLKSPVPFLLGTSPSADGPDSFSCVFEAILESHRAKGTSYSSLASLEALASPGPTQSPFFTFEMPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQRREVEESDAGATLAPRKELPSPSHSEDSFGLGAAPLGSEPPLSQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRVSGGSGSSSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAHLGKKARGKEADEQRQKEAYLEFEKSRYGTYAALLRVKMKAASEELDTIEAALAQAGSTEDGCPPPHSSPSLRPKPTSQPRAQRPGSETRAGAGSTRPKP", "length": 1024 }, "evidence": [ { "id": "G5E560", "url": "https://omabrowser.org/oma/group/G5E560/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "G5E560", "url": "https://www.uniprot.org/uniprotkb/G5E560" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1001, "end_pos": 1003, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E560-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1026, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E560-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E560" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E560" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 758, "end_pos": 871, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E560", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E560" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 543, "end_pos": 708, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 138, 437 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1001, "end_pos": 1003 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7R9-1", "uniprot_ac": "G3X7R9", "uniprot_id": "G3X7R9_BOVIN", "mass": { "chemical_mass": 76001.0, "monoisotopic_mass": 76001.0 }, "refseq": { "ac": "XP_024837990", "name": "transcription factor IIIB 90 kDa subunit isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837990" }, "gene_names": [ { "name": "BRF1", "type": "recommended", "evidence": [ { "id": "G3X7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ] }, { "name": "BRF1", "type": "synonym", "evidence": [ { "id": "XP_024837990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837990" } ] } ], "protein_names": [ { "name": "Transcription factor IIIB 90 kDa subunit", "type": "recommended", "evidence": [ { "id": "G3X7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7R9/entry#names_and_taxonomy" } ] }, { "name": "B-related factor 1", "type": "synonym", "evidence": [ { "id": "G3X7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7R9/entry#names_and_taxonomy" } ] }, { "name": "transcription factor IIIB 90 kDa subunit isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024837990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837990" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BRF1", "url": "https://www.uniprot.org/uniprotkb/G3X7R9", "locus": { "chromosome": "21", "start_pos": 69557558, "end_pos": 69607727, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012753", "url": "https://www.ensembl.org/id/ENSBTAG00000012753" } ] } } ], "crossref": [ { "id": "G3X7R9", "url": "https://alphafold.ebi.ac.uk/entry/G3X7R9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012753", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20553", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20553", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20554", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20554", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618161", "url": "https://www.ncbi.nlm.nih.gov/gene/618161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EPPCKVM", "url": "https://omabrowser.org/oma/group/EPPCKVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M2J2", "url": "https://www.orthodb.org/?gene=A0A3Q1M2J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X7R9", "url": "https://www.orthodb.org/?gene=G3X7R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024837990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837990", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2J2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5D1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5D1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7R9-1", "url": "https://www.uniprot.org/uniprotkb/G3X7R9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKAPTLGGGFHVSLGKESRAQTLQNGRRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRRTAHVVAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTVDEFMKIDLEEECDPPSYTAGQRKLRLKQLEQVLSKQLEAVEGEITTYQDAIEIELENSRPKAKGALASLTKDGSVEDSTSSLCGEEDTEDEELEAAASHLNKDFYQELLGGSVPGSSEAAGVPEEGRRPPALESLLGPLPTAASLGISDSIRECISSPSHEPKDACGDGELDLSGIDDLEIDRYILNEAEARVKAELWMRENAEYLREQKEKEARIAKERELGIYKEHKPKKSCKRREPIQASTAGEAIEKMLEQKKISSKINYSVLRGLDAGGGPPGEDGPPPREHGPPPGEDTGPQGEAARPPEWTSARRLSRRKTSSRRSRPDPSTSAGKRLRPLVSTQPAKKVALGEASLPSAHSLEAERVRPTVVVVESGPVSYHAEEDAEEEDAEEEDGEPCVSALQMMGGNDYGCDGDDDDGY", "length": 697, "header": "tr|G3X7R9-1|G3X7R9_BOVIN Isoform 1 of Transcription factor IIIB 90 kDa subunit OS=Bos taurus OX=9913 GN=BRF1 PE=3 SV=2 CANONICAL=G3X7R9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2J2/entry", "sequence": { "sequence": "MHWWFWPEVELKLSSRLQRSPAGGAGKAPTLGGGFHVSLGKESRAQTLQNGRRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRRTAHVVAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTVDEFMKIDLEEECDPPSYTAGQRKLRLKQLEQVLSKQLEAVEGEITTYQDAIEIELENSRPKAKGALASLTKDGSVEDSTSSLCGEEDTEDEELEAAASHLNKDFYQELLGGSVPGSSEAAGVPEEGRRPPALESLLGPLPTAASLGISDSIRECISSPSHEPKDACGDGELDLSGIDDLEIDRYILNEAEARVKAELWMRENAEYLREQKEKEARIAKERELGIYKEHKPKKSCKRREPIQASTAGEAIEKMLEQKKISSKINYSVLRGLDAGGGPPGEDGPPPREHGPPPGEDTGPQGEAARPPEWTSARRLSRRKTSSRRSRPDPSTSAGKRLRPLVSTQPAKKVALGEASLPSAHSLEAERVRPTVVVVESGPVSYHAEEDAEEEDAEEEDGEPCVSALQMMGGNDYGCDGDDDDGY", "length": 659, "header": "tr|A0A3Q1M2J2-1|G3X7R9_BOVIN Computationally mapped isoform of Transcription factor IIIB 90 kDa subunit OS=Bos taurus OX=9913 GN=BRF1 PE=3 SV=1 CANONICAL=G3X7R9-1" }, "locus": { "chromosome": "21", "start_pos": 69605011, "end_pos": 69558562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072155.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072155.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064016.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064016.1" } ] } }, { "isoform_ac": "A0AAA9T5D1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5D1/entry", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGRRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRRTAHVVAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTVDEFMKIDLEEECDPPSYTAGQRKLRLKQLEQVLSKQLEAVEGEITTYQDAIEIELENSRPKAKGALASLTKDGSVEDSTSSLCGEEDTEDEELEAAASHLNKDFYQELLGGSVPGSSEAAGVPEEGRRPPALESLLGPLPTAASLGISDSIRECISSPSHEPKDACGDGELDLSGIDDLEIDRYILNEAEARVKAELWMRENAEYLREQKEKEARIAKERELGIYKEHKPKKSCKRREPIQASTAGEAIEKMLEQKKISSKINYSVLRGLDAGGGPPGEDGPPPREHGPPPGEDTGPQGEAARPPEWTSARRLSRRKTSSRRSRPDPSTSAGKRLRPLVSTQPAKKVALGEASLPSAHSLEAERVRPTVVVVESGPVSYHAEEDAEEEDAEEEDGEPCVSALQMMGGNDYGCDGDDDDGY", "length": 670, "header": "tr|A0AAA9T5D1-1|G3X7R9_BOVIN Computationally mapped isoform of Transcription factor IIIB 90 kDa subunit OS=Bos taurus OX=9913 GN=BRF1 PE=3 SV=1 CANONICAL=G3X7R9-1" }, "locus": { "chromosome": "21", "start_pos": 69607528, "end_pos": 69558562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119639.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119639.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093975.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093975.1" } ] } }, { "isoform_ac": "G3X7R9-1", "url": "https://www.uniprot.org/uniprotkb/G3X7R9/entry", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKAPTLGGGFHVSLGKESRAQTLQNGRRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRRTAHVVAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTVDEFMKIDLEEECDPPSYTAGQRKLRLKQLEQVLSKQLEAVEGEITTYQDAIEIELENSRPKAKGALASLTKDGSVEDSTSSLCGEEDTEDEELEAAASHLNKDFYQELLGGSVPGSSEAAGVPEEGRRPPALESLLGPLPTAASLGISDSIRECISSPSHEPKDACGDGELDLSGIDDLEIDRYILNEAEARVKAELWMRENAEYLREQKEKEARIAKERELGIYKEHKPKKSCKRREPIQASTAGEAIEKMLEQKKISSKINYSVLRGLDAGGGPPGEDGPPPREHGPPPGEDTGPQGEAARPPEWTSARRLSRRKTSSRRSRPDPSTSAGKRLRPLVSTQPAKKVALGEASLPSAHSLEAERVRPTVVVVESGPVSYHAEEDAEEEDAEEEDGEPCVSALQMMGGNDYGCDGDDDDGY", "length": 697, "header": "tr|G3X7R9-1|G3X7R9_BOVIN Isoform 1 of Transcription factor IIIB 90 kDa subunit OS=Bos taurus OX=9913 GN=BRF1 PE=3 SV=2 CANONICAL=G3X7R9-1" }, "locus": { "chromosome": "21", "start_pos": 69607528, "end_pos": 69558562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044278.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044278.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041784.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041784.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-BTA-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LQE8-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "Brf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGSQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISTYQDAIEIELENSRPKAKGALANLSKDGSGEDATSSPFCEEDTEDEELEAAASHMNKDFYRELLGADGGSEAAEDADGGSRPLALESLLGPLPTAASLGISDSIRECISSPSGDPKDSSGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQKEKEARIAKEKELGIYKEHKPKKSCKRREPILASTAGEAIEKMLEQKKISSKINYSVLRDLNSKGGGSPPRDDSQPPEHTSTKKLSRRKRAATRNSADPGTSMGKRLRPLVSAQPAKKAAVGEALLLNSPALGAEPVKPSAVLVESGPVSYHPEEDADEEDAEEEDGEPCVSALQMMGGNDYGCDGDEDDGY", "length": 676 }, "evidence": [ { "id": "G3X7R9", "url": "https://omabrowser.org/oma/group/G3X7R9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NQ85-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "BRF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPGGRVCAACGCSEIEVDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHANLGKESRAQTLQNGKRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHMLEFGDKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVIRVVKVCESTLRKRLTEFEYTPTSQLTIDEFMRIDLEEECDPPSFTAGQKKLKIQQLEKALSKKLEDFEGEISSYQDEIEIELENSRPKAKGVFANLSKSDSIEDNTLSIFGEEEAEDEELEAAANHLNKDFCNELLEKDRLKPGEDGDCKNGNEAPVRPPALESLLGPLPTAASLGITESIKECISSKDREPGENTGDGELDLSGIDDSEIDRYILNETEAQIKAELWMKENADYLKEQKEKEARIAKEKELGIYKEHKPKKAAKKREPIQASTAGEAIEKMLEQKKISSKINYNVLRDLNSKGSNTPKKEDDSTDDSTNTKKLSRRKSIASRNIASPVNSVGKRLRPLISTQLAKKAATEEVTFPNAPAEASNIEKPATVLVESGPVAYNLDEEVEEEEAEEEDDHCMSALQLMGGNDYGCDMDDDDGY", "length": 681 }, "evidence": [ { "id": "G3X7R9", "url": "https://omabrowser.org/oma/group/G3X7R9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P29056-1", "protein_name": "Transcription factor IIIB 70 kDa subunit", "gene_name": "BRF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVTFGETSAGAAVVQGSFIGAGQSHAAFGGSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDGEARPPSFVKNRKKERKIKDSLDKEEMFQTSEEALNKNPILTQVLGEQELSSKEVLFYLKQFSERRARVVERIKATNGIDGENIYHEGSENETRKRKLSEVSIQNEHVEGEDKETEGTEEKVKKVKTKTSEEKKENESGHFQDAIDGYSLETDPYCPRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWIGLNADFLLEQESKRLKQEADIATGNTSVKKKRTRRRNNTRSDEPTKTVDAAAAIGLMSDLQDKSGLHAALKAAEESGDFTTADSVKNMLQKASFSKKINYDAIDGLFR", "length": 596 }, "evidence": [ { "id": "G3X7R9", "url": "https://omabrowser.org/oma/group/G3X7R9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8CFK2-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "Brf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGSQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGALANLSKDGSGEDATSSPRCEEDTEDEELEAAASHMNKDFYRELLGDDDGSEAAGDPDGGSRPLALESLLGPLPTAASLGISDSIRECISSPSGDPKDSSGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQKEKEARIAKEKELGIYKEHKPKKSCKRREPILASTAGEAIEKMLEQKKISSKINYSVLRDLNSKGGGSPPRDDSQPPERASTKKLSRRKRATTRNSADPGTSTGKRLRPLLSAQPAKKAAVGEALLLSSPALGAEPVKPSAVLVESGPVPYHPEEDADEEDAEDEDGEPCVSALQMMGGNDYGCDGDEDDGY", "length": 676 }, "evidence": [ { "id": "G3X7R9", "url": "https://omabrowser.org/oma/group/G3X7R9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92994-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "BRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGDEDDGY", "length": 677 }, "evidence": [ { "id": "G3X7R9", "url": "https://omabrowser.org/oma/group/G3X7R9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEL2-1", "protein_name": "B-related factor 1", "gene_name": "Brf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTGLKCRNCGSNEIEEDNARGDRVCMNCGSVLEDSLIVSEVQFEEVGHGAAAIGQFVSAESSGGATNYGYGKFQVGSGTESREVTIKKAKKDITLLCQQLQLSQHYADTALNFFKMALGRHLTRGRKSTHIYAACVYMTCRTEGTSHLLIDISDVQQICSYELGRTYLKLSHALCINIPSLDPCLYIMRFANRLQLGAKTHEVSMTALRIVQRMKKDCMHSGRRPTGLCGAALLIAARMHDFSRTMLDVIGVVKIHESTLRKRLSEFAETPSGGLTLEEFMTVDLEREQDPPSFKAARKKDRERIKDMGEHELTELQKEIDAHLEKDLGKYSNSVYRQLTKGKGLSPLSSPSTPNSSSEKDIELEESRQFIEQSNAEVIKELIAKNEDVKKSEPGGLVAGIEGLRPDIEAICRVTQSDLEDVEKAKQPQEQELITDDLNDDELDQYVLTEEESVAKLEMWKNLNAEYLQEQKERDERLAKEREEGKPERKKRKPRKKVIGPSSTAGEAIEKMLQEKKISSKINYEILKTLTDGMGGLTDDSPTTSADTKPSTLEELKHQPVIVEEGPVASKSRGNRAAYDLPGPSRKRPKLEVGLPVSKAADVEQAETKPAVVVEADDLDEDADDPDVEPEAEPEATLQDMLNTGGDDDEFGYGFDEEEEY", "length": 662 }, "evidence": [ { "id": "G3X7R9", "url": "https://omabrowser.org/oma/group/G3X7R9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" }, { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" }, { "name": "transcription factor TFIIIB complex", "id": "GO:0000126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000126", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" }, { "name": "RNA polymerase III type 3 promoter sequence-specific DNA binding", "id": "GO:0001006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001006", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transcription preinitiation complex assembly", "id": "GO:0070897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070897", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "G3X7R9", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7R9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 697, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7R9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7R9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7R9" }, { "id": "PS51134", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51134" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIIB-type", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 33, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 540, "end_pos": 542 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RPH3-1", "uniprot_ac": "F6RPH3", "uniprot_id": "F6RPH3_BOVIN", "mass": { "chemical_mass": 51424.0, "monoisotopic_mass": 51424.0 }, "refseq": {}, "gene_names": [ { "name": "MAPK13", "type": "recommended", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ], "protein_names": [ { "name": "Mitogen-activated protein kinase 13", "type": "recommended", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.24", "type": "synonym", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAPK13", "url": "https://www.uniprot.org/uniprotkb/F6RPH3", "locus": { "chromosome": "23", "start_pos": 10067019, "end_pos": 10058281, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010007", "url": "https://www.ensembl.org/id/ENSBTAG00000010007" } ] } } ], "crossref": [ { "id": "F6RPH3", "url": "https://alphafold.ebi.ac.uk/entry/F6RPH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010007", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07879", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07879", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M757", "url": "https://www.orthodb.org/?gene=A0A3Q1M757", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MGB3", "url": "https://www.orthodb.org/?gene=A0A3Q1MGB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M757", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M757", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M757-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M757-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1V1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1V1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPH3-1", "url": "https://www.uniprot.org/uniprotkb/F6RPH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVPNSDPGGNPGLPGAAAGQARAWPRSAPGRGGRWDAWPGRGPALAQGRSGRPGRAPRAPRAGARCWEPGEPRAQPPRWGRQHRVPGMSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLNDKAAKSYIQSLPQSPKKDFSQLFPRASPQATDLLEKMLELDVDKRLTASQALAHPFFEPFRDPEEETEAQQPLEDSLEREKLTVDEWKQHIYKEIVNFSPIARKDSRRRSGMKLQ", "length": 455, "header": "tr|F6RPH3-1|F6RPH3_BOVIN Isoform 1 of Mitogen-activated protein kinase 13 OS=Bos taurus OX=9913 GN=MAPK13 PE=3 SV=1 CANONICAL=F6RPH3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M757-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M757/entry", "sequence": { "sequence": "MSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVWGACSLLTWEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSEDKIQYLVYQMLKGLKDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLNDKAAKSYIQSLPQSPKKDFSQLFPRASPQATDLLEKMLELDVDKRLTASQALAHPFFEPFRDPEEETEAQQPLEDSLEREKLTVDEWKQHIYKEIVNFSPIARKDSRRRSGMKLQ", "length": 356, "header": "tr|A0A3Q1M757-1|F6RPH3_BOVIN Computationally mapped isoform of Mitogen-activated protein kinase 13 OS=Bos taurus OX=9913 GN=MAPK13 PE=3 SV=1 CANONICAL=F6RPH3-1" }, "locus": { "chromosome": "23", "start_pos": 10066769, "end_pos": 10058713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076896.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076896.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064235.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064235.1" } ] } }, { "isoform_ac": "A0A3Q1MGB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGB3/entry", "sequence": { "sequence": "MSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSEDKIQYLVYQMLKGLKDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLNDKAAKSYIQSLPQSPKKDFSQLFPRASPQATDLLEKMLELDVDKRLTASQALAHPFFEPFRDPEEETEAQQPLEDSLEREKLTVDEWKQHIYKEIVNFSPIARKDSRRRSGMKLQ", "length": 356, "header": "tr|A0A3Q1MGB3-1|F6RPH3_BOVIN Computationally mapped isoform of Mitogen-activated protein kinase 13 OS=Bos taurus OX=9913 GN=MAPK13 PE=3 SV=1 CANONICAL=F6RPH3-1" }, "locus": { "chromosome": "23", "start_pos": 10066769, "end_pos": 10058713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067132.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067132.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069580.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069580.1" } ] } }, { "isoform_ac": "A0AAA9S1V1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1V1/entry", "sequence": { "sequence": "MSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTGQILHPVPATKPQKGFLSAIPACQPPGHRPAGEDAGAGRGQAPDGLAGPRPPLL", "length": 257, "header": "tr|A0AAA9S1V1-1|F6RPH3_BOVIN Computationally mapped isoform of Mitogen-activated protein kinase 13 OS=Bos taurus OX=9913 GN=MAPK13 PE=3 SV=1 CANONICAL=F6RPH3-1" }, "locus": { "chromosome": "23", "start_pos": 10066335, "end_pos": 10058713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092667.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092667.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076060.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076060.1" } ] } }, { "isoform_ac": "F6RPH3-1", "url": "https://www.uniprot.org/uniprotkb/F6RPH3/entry", "sequence": { "sequence": "MAGVPNSDPGGNPGLPGAAAGQARAWPRSAPGRGGRWDAWPGRGPALAQGRSGRPGRAPRAPRAGARCWEPGEPRAQPPRWGRQHRVPGMSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLNDKAAKSYIQSLPQSPKKDFSQLFPRASPQATDLLEKMLELDVDKRLTASQALAHPFFEPFRDPEEETEAQQPLEDSLEREKLTVDEWKQHIYKEIVNFSPIARKDSRRRSGMKLQ", "length": 455, "header": "tr|F6RPH3-1|F6RPH3_BOVIN Isoform 1 of Mitogen-activated protein kinase 13 OS=Bos taurus OX=9913 GN=MAPK13 PE=3 SV=1 CANONICAL=F6RPH3-1" }, "locus": { "chromosome": "23", "start_pos": 10066769, "end_pos": 10058446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013198.7", "url": "https://www.ensembl.org/id/ENSBTAT00000013198.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013198.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013198.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "MAP kinase activity", "id": "GO:0004707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004707", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "cellular response to sorbitol", "id": "GO:0072709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072709", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "response to osmotic stress", "id": "GO:0006970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006970", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "cellular response to hydrogen peroxide", "id": "GO:0070301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070301", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "stress-activated MAPK cascade", "id": "GO:0051403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051403", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "cellular response to interleukin-1", "id": "GO:0071347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071347", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "cellular response to sodium arsenite", "id": "GO:1903936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903936", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" }, { "name": "cellular response to anisomycin", "id": "GO:0072740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072740", "evidence": [ { "database": "UniProtKB", "id": "F6RPH3", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", 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"F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 397, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.24", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2U0-1", "uniprot_ac": "G3N2U0", "uniprot_id": "G3N2U0_BOVIN", "mass": { "chemical_mass": 88304.0, "monoisotopic_mass": 88304.0 }, "refseq": { "ac": "XP_005210974", "name": "lethal(3)malignant brain tumor-like protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210974" }, "gene_names": [ { "name": "L3MBTL3", "type": "recommended", "evidence": [ { "id": "G3N2U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ] }, { "name": "L3MBTL3", "type": "synonym", "evidence": [ { "id": "XP_005210974", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210974" } ] } ], "protein_names": [ { "name": "L3MBTL histone methyl-lysine binding protein 3", "type": "synonym", "evidence": [ { "id": "G3N2U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2U0/entry#names_and_taxonomy" } ] }, { "name": "lethal(3)malignant brain tumor-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005210974", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210974" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "L3MBTL3", "url": "https://www.uniprot.org/uniprotkb/G3N2U0", "locus": { "chromosome": "9", "start_pos": 68286641, "end_pos": 68182877, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017393", "url": "https://www.ensembl.org/id/ENSBTAG00000017393" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017393", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017393", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09582", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09582", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20132", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20132", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20135", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20135", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20138", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524334", "url": "https://www.ncbi.nlm.nih.gov/gene/524334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QFCENCY", "url": "https://omabrowser.org/oma/group/QFCENCY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N2U0", "url": "https://www.orthodb.org/?gene=G3N2U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005210974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210974", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7X7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2U0-1", "url": "https://www.uniprot.org/uniprotkb/G3N2U0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMENVKKATATTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNHCSQNCARHIKDNRDQKEERDMGEDNEEEDSKCSRKKKPKLSLKADSKEEEERDDEMENKQDGRILRGSQRARRKRRGDSVVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEYQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPAFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVIDKRNPMFIRVATVADTDDHRIKVHFDGWNSCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLDLMEASEHGGCTTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRSKRADTNEISSSPETRDQRAEDVKEDFEERTESELRTPHEARGAREESSVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 780, "header": "tr|G3N2U0-1|G3N2U0_BOVIN Isoform 1 of L3MBTL histone methyl-lysine binding protein 3 OS=Bos taurus OX=9913 GN=L3MBTL3 PE=4 SV=2 CANONICAL=G3N2U0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7X7/entry", "sequence": { "sequence": "MFRVNEFGALEVITDESEMENVKKATATTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNHCSQNCARHIKDKDQKEERDMGEDNEEEDSKCSRKKKPKLSLKADSKEEEERDDEMENKQDGRILRGSQRARRKRRGDSVVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEYQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPAFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVIDKRNPMFIRVATVADTDDHRIKVHFDGWNSCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLDLMEASEHGGCTTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRSKRADTNEISSSPETRDQRAEDVKEDFEERTESELRTPHEARGAREESSVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 746, "header": "tr|A0A3Q1M7X7-1|G3N2U0_BOVIN Computationally mapped isoform of L3MBTL histone methyl-lysine binding protein 3 OS=Bos taurus OX=9913 GN=L3MBTL3 PE=4 SV=2 CANONICAL=G3N2U0-1" }, "locus": { "chromosome": "9", "start_pos": 68284947, "end_pos": 68211319, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083072.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083072.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066186.3", "url": "https://www.ensembl.org/id/ENSBTAP00000066186.3" } ] } }, { "isoform_ac": "G3N2U0-1", "url": "https://www.uniprot.org/uniprotkb/G3N2U0/entry", "sequence": { "sequence": "MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMENVKKATATTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNHCSQNCARHIKDNRDQKEERDMGEDNEEEDSKCSRKKKPKLSLKADSKEEEERDDEMENKQDGRILRGSQRARRKRRGDSVVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEYQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPAFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVIDKRNPMFIRVATVADTDDHRIKVHFDGWNSCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLDLMEASEHGGCTTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRSKRADTNEISSSPETRDQRAEDVKEDFEERTESELRTPHEARGAREESSVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 780, "header": "tr|G3N2U0-1|G3N2U0_BOVIN Isoform 1 of L3MBTL histone methyl-lysine binding protein 3 OS=Bos taurus OX=9913 GN=L3MBTL3 PE=4 SV=2 CANONICAL=G3N2U0-1" }, "locus": { "chromosome": "9", "start_pos": 68284947, "end_pos": 68203802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064787.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064787.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056210.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056210.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480QFR5-1", "protein_name": "L3MBTL histone methyl-lysine binding protein 3", "gene_name": "L3MBTL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMENVKKATATTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGVPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNYCSQNCARHIKDNRDLKEERDVGEDNEEEDPKCSRKKKPKLSLKADSKEEEERDDEMENKQDGRILRGSQRARRKRRGDAAVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEYQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPAFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVIDKRNPVFIRVATVADTDDHRIKVHFDGWNSCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRNKRADTNEISSSPEIRDQHADDAKEDFEERTEIEMRTSHEARGAREEPSVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 780 }, "evidence": [ { "id": "G3N2U0", "url": "https://omabrowser.org/oma/group/G3N2U0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XG13-1", "protein_name": "L3MBTL histone methyl-lysine binding protein 3", "gene_name": "L3MBTL3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLTCARSPGPYLSGPTREPEKKREREFGGYIIKKCKKWKDEKETSVWCALLEQIVVRRKVGSPCTCIMNESASSGNGQEFDVFSVMDWKDGIGTLPGSDLKFRVNEFGALEVITDENEMESVKKAMATTTWMVPTAQEAFSEKTGISTKLKETAKMDGLVFCENCYHYGTVEEFVPEGKFCSQKCAQQVKNKEPKEEKPNMECNGDDESKVIRKRKTKLPLKEESRDNEEKKENPDETEDKSEGRILRVSQRARRKRKGEITVLKQTVSSKGKQAWCWASYLEEEKAIAVPTKLFKEYQSFPYNKNGFKVGMKLEGVDPEHQSIYCVLTVAEVCGYRIRLHFDGYPDCYDFWVNADSSDIHPVGWCEKTGHKLHPPKGYKEEEFNWPSYLKACKAQAAPKSLFENQNATVIPSGFRVGMKLEAVDKKNPTFVCVATVTDMVDNRFLVHFDNWDESYDYWCEAASPHIHPVGWCKEHKRTLITPPDYPHAKHFSWEKYLEETSSLPAPARAFKVKPSHGFQKNMKLEVVDKRNPVFIRVATIVDTDDYRIKVHFDGWDSIYDYWTDVDSPDIHPAGWCTKTGHPLQPPLSPLELVEALEHGGCPTAGCKGVGHVKRARHIGHHSAVSCPYSEMNLNKESLLPDRLSGELPAANPVPRNRRVEARERSPSPIINDRKCPSPGHIGTKSAAHNRSSGKTVSETTKQEDRESASPCKKSLLCDVKEKKPPGGVLQTKDSVKNKECEEKETENNLLISNEIKVIEEPNTQRLLSQPVVVSSKLQIPGLPLRWEQQSKLLPSVAGIPASKVSKWSTDEVSEFIRSLPGCEEHGKVFKDEQIDGEAFLLMTQSDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 880 }, "evidence": [ { "id": "G3N2U0", "url": "https://omabrowser.org/oma/group/G3N2U0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZJT9-1", "protein_name": "L3MBTL histone methyl-lysine binding protein 3", "gene_name": "L3mbtl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTESSSTTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMESVKKATATTTWMVPTAQDAPPSPLSSRPAFPPAYWTSPPGCPTVFSEKTGVPFRLKEQSKVDGLQFCENCCQYGNGEECLSGGNYCSQNCSRRARDKDQKEDRDGGEDNDEEDPKCSRKKKPKLSLKADSKEDEERDDEMENKQDGRILRGSQRARRKRRGDSAVLKQGLPPKGKKTWCWASYLEEEKAVAVPTKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLRPPKGYKEEEFNWQSYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAADKKSPSIICVATVTDMVDNRFLVHFDNWDESYDYWCESNSPHIHPVGWCKEHRRTLITPPGYSHVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEAVDKRNPLFIRVATVADTDDHRIKVHFDGWSSCYDYWIDADSPDIHPVGWCSKTGHPLQAPLSPAELMEPSETGGCPTLGCRGVGHFKKSRYLGTQSGANCPYSEINLSKDRIFPDRLSGEITPSSFSFPRSKRTDTNESSSSPETRDQHANNVKEDSEKKKENEVKTSAEAKVVREEPTPSVQQTQPPQQALKAPQAPQIQPAQQAPQAPQAQPTQQQAQQAQQAPQAPQAQPAPQAPQTHPTQQQAQQAQPTQQQAQQAQPTQQQQAQQQAQRRSAVFLSFKPPIPCLPLRWEQQSKLLPTVAGIPASRVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 868 }, "evidence": [ { "id": "G3N2U0", "url": "https://omabrowser.org/oma/group/G3N2U0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BLB7-1", "protein_name": "Lethal(3)malignant brain tumor-like protein 3", "gene_name": "L3mbtl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDESEMESVKKATATTTWMVPTAQDAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGVPFRLKEQSKADGLQFCENCCQYGNGDECLSGGKYCSQNCARHAKDKDQKDERDGGEDNDEEDPKCSRKKKPKLSLKADSKDDGEERDDEMENKQDGRILRGSQRARRKRRGDSAVLKQGLPPKGKKTWCWASYLEEEKAVAVPTKLFKEHQSFPYNKNGFKVGMKLEGVDPDHQAMYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLRPPKGYKEEEFNWQSYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAADKKSPSVICVATVTDMVDNRFLVHFDNWDESYDYWCESNSPHIHPVGWCKEHRRTLITPPGYSHVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEAVDKRNPLFIRVATVADTDDHRIKVHFDGWSSCYDYWIDADSPDIHPVGWCSKTGHPLQAPLSPAELMEPSETGGCPTLGCRGVGHFKKSRYLGTQSGANCPYSEINLSKERIFPDRLSGDTSPPTTPSFPRSKRMDTRESSSSPETREKHANNFKEDSEKKKENEVKTSAEAKVVREEPTPSVQQSQPPQQVQQVQHAQPPQQAQKAPQAQQAQQAQQAQQAPQAPQTPQPQQAPQVQQAQQAPQAQQAQQPQQAQQPQQAPPVQQPQQVQQAQPTQQQAQTQQQAQRRSAVFLSFKPPIPCLPLRWEQQSKLLPTVAGIPASRVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 883 }, "evidence": [ { "id": "G3N2U0", "url": "https://omabrowser.org/oma/group/G3N2U0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JM7-1", "protein_name": "Lethal(3)malignant brain tumor-like protein 3", "gene_name": "L3MBTL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATATTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFCENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLKADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEEEKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASSPHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRLSGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREEPTVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL", "length": 780 }, "evidence": [ { "id": "G3N2U0", "url": "https://omabrowser.org/oma/group/G3N2U0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "negative regulation of transcription initiation-coupled chromatin remodeling", "id": "GO:0160217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160217", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" }, { "name": "methylation-dependent protein binding", "id": "GO:0140034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140034", "evidence": [ { "database": "UniProtKB", "id": "G3N2U0", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" }, { "id": "PS51079", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBT", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 332, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N2U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2U0" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 708, "end_pos": 772, "start_aa": "Trp", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF25520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002685395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685395", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7Z4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQE7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N014", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N014", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N014-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N014-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6E6-1", "url": "https://www.uniprot.org/uniprotkb/G3X6E6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKAVLKKSREGGKGSKKETGGDFGPETSPPVLPPGHGGEFSVSSLPVAEDAYRVSLAKGVSMSLPSSPLLPRQSHSVPSRSTKKSPGPVRKPKYVESPRVPGDAVIIPFRDVPKPAEPSENEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEEKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGSLRLGVQKGVLHDRRADNCSPVAEEEPPGPAESVLPKAEASVGDGPVPYSQSSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELTENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPSSSTKTSDSSQDVPFTPLLSPTSSTSGSGAAKSPPVSGSDPENQRPREDSVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIREPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIVSELPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHVQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMTALCYAAAAGHMKLVCLLAKKGARVDHLDKKGQCALVHSALRGHGDVLRYLLTCEWSLGPPQPGALRKSQALQQALTAAASMGHGSVLQCLLELEKEHEIDVNGTDTLWGETALTAAAGRGKLEVCELLLERGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLDHGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGATLSSLDKEGLSALSWACLKGHRAVVQFLVEEGAEIDQTDKNGRSPLDLAAFYGDAETVLYLVDKGAVIEHVDHSGMRPLDRAIGCRNTSVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRSSRQFVAALADLREAVKLCPANQEIRRLLARVEEECKQLQRSQQQKQQAPPPAPPTDSDNEEYAPTPGLNDHFHLEGAEEEETSPPEEAVSLAPRPPPSSSAPSPYIRNLQEGLQPKIRPVSPLQSRPGAGKALREAVAQPGLTVQPTKQAQIVKTSQHLGSGPAGVRNSSSKTQVSPLNPPPSPMPGRLPTAPAGSRSLHLEGAASGPFGDRLGPSPAVHLQHSEGDAAYPLPSKIKSAERLLSHAAVAVDVVPLNPGGPVSCSDTRHPTSLSSSGSSGSPSSSIKMSSSTSSLASSSSFSDGFKVQGPDARIKDKVGSQVPSGTAEHRPRNTPFMGIMDKTARFQQQNHPPGRTWHCAVSEGLLTGTPSAAGLQASNSEKPSLKQAKACPGSTLGGGVHNGAQVKEPEEKKCQMPVHCQDSRVTKTISHLYQESMSKQQSHISSEAHRSHLPSAKPKRSFIESNV", "length": 1850, "header": "tr|G3X6E6-1|G3X6E6_BOVIN Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Bos taurus OX=9913 GN=TANC1 PE=3 SV=3 CANONICAL=G3X6E6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Z4/entry", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKETGGDFGPETSPPVLPPGHGGEFSVSSLPVAEDAYRVSLAKGVSMSLPSSPLLPRQSHSVPSRSTKKSPGPVRKPKYVESPRVPGDAVIIPFRDVPKPAEPSENAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEEKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGSLRLGVQKGVLHDRRADNCSPVAEEEPPGPAESVLPKAEASVGDGPVPYSQSSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELTENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPSSSTKTSDSSQDVPFTPLLSPTSSTSGSGAAKSPPVSGSDPENQRPREDSVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIREPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIVSELPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHVQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMTALCYAAAAGHMKLVCLLAKKGARVDHLDKKGQCALVHSALRGHGDVLRYLLTCEWSLGPPQPGALRKSQALQQALTAAASMGHGSVLQCLLELEKEHEIDVNGTDTLWGETALTAAAGRGKLEVCELLLERGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLDHGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGATLSSLDKEGLSALSWACLKGHRAVVQFLVEEGAEIDQTDKNGRSPLDLAAFYGDAETVLYLVDKGAVIEHVDHSGMRPLDRAIGCRNTSVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRSSRQFVAALADLREAVKLCPANQEIRRLLARVEEECKQLQRSQQQKQQAPPPAPPTDSDNEEYAPTPGLNDHFHLEGAEEEETSPPEEAVSLAPRPPPSSSAPSPYIRNLQEGLQPKIRPVSPLQSRPGAGKALREAVAQPGLTVQPTKQAQIVKTSQHLGSGPAGVRNSSSKTQVSPLNPPPSPMPGRLPTAPAGSRSLHLEGAASGPFGDRLGPSPAVHLQHSEGDAAYPLPSKIKSAERLLSHAAVAVDVVPLNPGGPVSCSDTRHPTSLSSSGSSGSPSSSIKMSSSTSSLASSSSFSDGFKVQGPDARIKDKVGSQVPSGTAEHRPRNTPFMGIMDKTARFQQQNHPPGRTWHCAVSEGLLTGTPSAAGLQASNSEKPSLKQAKACPGSTLGGGVHNGAQVKEPEEKKCQMPVHCQDSRVTKTISHLYQESMSKQQSHISSEAHRSHLPSAKPKRSFIESNV", "length": 1842, "header": "tr|A0A3Q1M7Z4-1|G3X6E6_BOVIN Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Bos taurus OX=9913 GN=TANC1 PE=3 SV=3 CANONICAL=G3X6E6-1" }, "locus": { "chromosome": "2", "start_pos": 37302316, "end_pos": 37135011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069869.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069869.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069991.3", "url": "https://www.ensembl.org/id/ENSBTAP00000069991.3" } ] } }, { "isoform_ac": "A0A3Q1MQE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQE7/entry", "sequence": { "sequence": "MLGSSGPVRKPKYVESPRVPGDAVIIPFRDVPKPAEPSENEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEEKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGSLRLGVQKGVLHDRRADNCSPVAEEEPPGPAESVLPKAEASVGDGPVPYSQSSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELTENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPSSSTKTSDSSQDVPFTPLLSPTSSTSGSGAAKSPPVSGSDPENQRPREDSVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIREPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIVSELPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHVQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMTALCYAAAAGHMKLVCLLAKKGARVDHLDKKGQCALVHSALRGHGDVLRYLLTCEWSLGPPQPGALRKSQALQQALTAAASMGHGSVLQCLLELEKEHEIDVNGTDTLWGETALTAAAGRGKLEVCELLLERGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLDHGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGATLSSLDKEGLSALSWACLKGHRAVVQFLVEEGAEIDQTDKNGRSPLDLAAFYGDAETVLYLVDKGAVIEHVDHSGMRPLDRAIGCRNTSVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRSSRQFVAALADLREAVKLCPANQEIRRLLARVEEECKQLQRSQQQKQQAPPPAPPTDSDNEEYAPTPGLNDHFHLEGAEEEETSPPEEAVSLAPRPPPSSSAPSPYIRNLQEGLQPKIRPVSPLQSRPGAGKALREAVAQPGLTVQPTKQAQIVKTSQHLGSGPAGVRNSSSKTQVSPLNPPPSPMPGRLPTAPAGSRSLHLEGAASGPFGDRLGPSPAVHLQHSEGDAAYPLPSKIKSAERLLSHAAVAVDVVPLNPGGPVSCSDTRHPTSLSSSGSSGSPSSSIKMSSSTSSLASSSSFSDGFKVQGPDARIKDKVGSQVPSGTAEHRPRNTPFMGIMDKTARFQQQNHPPGRTWHCAVSEGLLTGTPSAAGLQASNSEKPSLKQAKACPGSTLGGGVHNGAQVKEPEEKKCQMPVHCQDSRVTKTISHLYQESMSKQQSHISSEAHRSHLPSAKPKRSFIESNV", "length": 1761, "header": "tr|A0A3Q1MQE7-1|G3X6E6_BOVIN Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Bos taurus OX=9913 GN=TANC1 PE=3 SV=1 CANONICAL=G3X6E6-1" }, "locus": { "chromosome": "2", "start_pos": 37251242, "end_pos": 37135011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075552.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075552.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074232.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074232.1" } ] } }, { "isoform_ac": "A0A3Q1N014-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N014/entry", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKETGGDFGPETSPPVLPPGHGGEFSVSSLPVAEDAYRVSLAKGVSMSLPSSPLLPRQSHSVPSRSTKKSPGPVRKPKYVESPRVPGDAVIIPFRDVPKPAEPSENEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEEKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELTENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPSSSTKTSDSSQDVPFTPLLSPTSSTSGSGAAKSPPVSGSDPENQRPREDSVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIREPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIVSELPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHVQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMTALCYAAAAGHMKLVCLLAKKGARVDHLDKKGQCALVHSALRGHGDVLRYLLTCEWSLGPPQPGALRKSQALQQALTAAASMGHGSVLQCLLELEKEHEIDVNGTDTLWGETALTAAAGRGKLEVCELLLERGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLDHGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGATLSSLDKEGLSALSWACLKGHRAVVQFLVEEGAEIDQTDKNGRSPLDLAAFYGDAETVLYLVDKGAVIEHVDHSGMRPLDRAIGCRNTSVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRSSRQFVAALADLREAVKLCPANQEIRRLLARVEEECKQLQRSQQQKQQAPPPAPPTDSDNEEYAPTPGLNDHFHLEGAEEEETSPPEEAVSLAPRPPPSSSAPSPYIRNLQEGLQPKIRPVSPLQSRPGAGKALREAVAQPGLTVQPTKQAQIVKTSQHLGSGPAGVRNSSSKTQVSPLNPPPSPMPGRLPTAPAGSRSLHLEGAASGPFGDRLGPSPAVHLQHSEGDAAYPLPSKIKSAERLLSHAAVAVDVVPLNPGGPVSCSDTRHPTSLSSSGSSGSPSSSIKMSSSTSSLASSSSFSDGFKVQGPDARIKDKVGSQVPSGTAEHRPRNTPFMGIMDKTARFQQQNHPPGRTWHCAVSEGLLTGTPSAAGLQASNSEKPSLKQAKACPGSTLGGGVHNGAQVKEPEEKKCQMPVHCQDSRVTKTISHLYQESMSKQQSHISSEAHRSHLPSAKPKRSFIESNV", "length": 1762, "header": "tr|A0A3Q1N014-1|G3X6E6_BOVIN Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Bos taurus OX=9913 GN=TANC1 PE=3 SV=1 CANONICAL=G3X6E6-1" }, "locus": { "chromosome": "2", "start_pos": 37302316, "end_pos": 37135011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066613.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066613.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061907.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061907.1" } ] } }, { "isoform_ac": "G3X6E6-1", "url": "https://www.uniprot.org/uniprotkb/G3X6E6/entry", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKETGGDFGPETSPPVLPPGHGGEFSVSSLPVAEDAYRVSLAKGVSMSLPSSPLLPRQSHSVPSRSTKKSPGPVRKPKYVESPRVPGDAVIIPFRDVPKPAEPSENEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEEKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGSLRLGVQKGVLHDRRADNCSPVAEEEPPGPAESVLPKAEASVGDGPVPYSQSSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELTENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPSSSTKTSDSSQDVPFTPLLSPTSSTSGSGAAKSPPVSGSDPENQRPREDSVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIREPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIVSELPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHVQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMTALCYAAAAGHMKLVCLLAKKGARVDHLDKKGQCALVHSALRGHGDVLRYLLTCEWSLGPPQPGALRKSQALQQALTAAASMGHGSVLQCLLELEKEHEIDVNGTDTLWGETALTAAAGRGKLEVCELLLERGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLDHGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGATLSSLDKEGLSALSWACLKGHRAVVQFLVEEGAEIDQTDKNGRSPLDLAAFYGDAETVLYLVDKGAVIEHVDHSGMRPLDRAIGCRNTSVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRSSRQFVAALADLREAVKLCPANQEIRRLLARVEEECKQLQRSQQQKQQAPPPAPPTDSDNEEYAPTPGLNDHFHLEGAEEEETSPPEEAVSLAPRPPPSSSAPSPYIRNLQEGLQPKIRPVSPLQSRPGAGKALREAVAQPGLTVQPTKQAQIVKTSQHLGSGPAGVRNSSSKTQVSPLNPPPSPMPGRLPTAPAGSRSLHLEGAASGPFGDRLGPSPAVHLQHSEGDAAYPLPSKIKSAERLLSHAAVAVDVVPLNPGGPVSCSDTRHPTSLSSSGSSGSPSSSIKMSSSTSSLASSSSFSDGFKVQGPDARIKDKVGSQVPSGTAEHRPRNTPFMGIMDKTARFQQQNHPPGRTWHCAVSEGLLTGTPSAAGLQASNSEKPSLKQAKACPGSTLGGGVHNGAQVKEPEEKKCQMPVHCQDSRVTKTISHLYQESMSKQQSHISSEAHRSHLPSAKPKRSFIESNV", "length": 1850, "header": "tr|G3X6E6-1|G3X6E6_BOVIN Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Bos taurus OX=9913 GN=TANC1 PE=3 SV=3 CANONICAL=G3X6E6-1" }, "locus": { "chromosome": "2", "start_pos": 37302316, "end_pos": 37135011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005473.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005473.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005473.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005473.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1449, "start_aa": "Thr", "end_pos": 1449, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1449", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:507983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507983", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YFN4-1", "protein_name": "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1", "gene_name": "TANC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARKTWVVPLPPAGGRAPSVKAAGVRVSKKQEAVPAGTNTRPTGRDKASIVSISKIHHMDVMLRKCHRTWQQHTPLSSCGGNIDVQSQTEGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1925 }, "evidence": [ { "id": "G3X6E6", "url": "https://omabrowser.org/oma/group/G3X6E6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q0VGY8-1", "protein_name": "Protein TANC1", "gene_name": "Tanc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKEAGGDFGSETPALSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSLLTQSRSNKKSPGPVRKPKYVESPRVPGDPVMIPFGEGSKPSEPSATEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAASKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRADNCSPVAEEETTGSAESVLPKAEPSAGDGPVPYPQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAPEVKARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELAENRGAVVVGSVGFGKTAIISKLVALSCHGSRMRQIASSSPSLSPKSSDPTQDLPGTPLLSPSSSTSALSVTRTPAGPGTADSQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIIPKFPTWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALISKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTMELGHHILKAHIFKGLSKKTGVSSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLIKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSSVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKVEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVRLLLDRGCDVNLSDKQGRTPLMVASCEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLVEEGNVMYKKGKMKEAAQRYQYALRKFPREGLGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPNNQEIKRLLARVEEECKQLQRNQQQKQQGPPPAPANDSDNEEDAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRSASPQSRAGISKSLRETVAQSGLVMQPTKQAQIVKTNQHLGSGQSSMRNSSTKIQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFTAGTGCGHFGDRLGASQSLQLQRSESGTAYPLPSKVKAAERLLAHASVAVDMAPPNQGGPVSCSDVRHPASLSSSGSSGSPSSSIKMSSSTSSLTSSSSVSDGFKVQGPDSRIRDKGTTQVQGGTAEHRPRNTPFMGIMDKTARFQQQSNPPNRSWHCPVAEGLLTNTATAAGLQSNSEKPTLKPGGYCSQAKPCSVPPLSMGVHNGAQVKELEENKCQIPALCQDNRITKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "length": 1856 }, "evidence": [ { "id": "G3X6E6", "url": "https://omabrowser.org/oma/group/G3X6E6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6F6B3-1", "protein_name": "Protein TANC1", "gene_name": "Tanc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKAVLKKSREGVKGSKKEAGGDFGSETPTLSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSHLTQSRANKKSPGPVRKPKYVESPRVPGDPVMIPFREGSKPAEPIETEAKVDNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRLDNCSPVAEEETTGSAESVLPKAESSAGDGPVPYSQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHSTAGARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFQQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQVASSSPSSSLKTSDPTHDLPGTPLLSPSSSTSALSAARTPPGPGTVDSQRPREDAVKYLASRVVAYHYCQADNTYTCLVPEFVHSIATLLCRSHQLAAYRDLLIREPQLQSMLNLRSCVQDPVAAFKRGILEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDHGDTLSSFITKIIPKFPPWLKLIVTVRADFQEIISTLPFVKLSLDDFPGNQDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSRLVLRNLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQKMEALSCFLIKKRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTVELGHHILKAHIFKGLSKKTGVSSSHPQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLTKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSAVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKLEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVQLLLDRGCDVNPNDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATFKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGPGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPTNQEIKRLLARVEEECKQLQRNQQQKQQAPLPAPPNDSDNDEEAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRPASPQSWAGISKSLRETVAQPGLVMQPTKQAQIVKTNQHLGSGQSSMRNSNTKVQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFSTGTGCGHFGDRLGPSQSLQLQRGESGTAYPLPSKVKAAERLLAHASVAVDMALPSQGGPVSCSDVRHPASLSSSGSSGSPSSSVKMSSSTSSLTSSSSVSDGFKAQGPDCRIRDRGTTQVQGGTAEHRPRNTPFMGIMDKIARFQQQVNPPSRSWHCPVTEGLLTNTATAAGLQTNSEKPALKPGGYCSQAKPCSVPPLGMGVHNGAQVKELEENKCQVPALCQDNRKTKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "length": 1849 }, "evidence": [ { "id": "G3X6E6", "url": "https://omabrowser.org/oma/group/G3X6E6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9C0D5-1", "protein_name": "Protein TANC1", "gene_name": "TANC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKAVLKKSREGGKGGKKEAGSDFGPETSPVLHLDHSADSPVSSLPTAEDTYRVSLAKGVSMSLPSSPLLPRQSHLVQSRVNKKSPGPVRKPKYVESPRVPGDAVIMPFREVAKPTEPDEHEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGNLRLGVQKGVLHDRRADNCSPVAEEETTGSAESTLPKAESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPTQDLHFTPLLSPSSSTSASSTAKTPLGSISAENQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADATLIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNLQEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSAVRNGSMKVQISSQNPPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQNVRLQCGENGPAHPLPSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGSSGSPSSSIKMSSSTSSLTSSSSFSDGFKVQGPDTRIKDKVVTHVQSGTAEHRPRNTPFMGIMDKTARFQQQSNPPSRSWHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQAKTCSVSTLSASVHNGAQVKELEESKCQIPVHSQENRITKTVSHLYQESISKQQPHISNEAHRSHLTAAKPKRSFIESNV", "length": 1861 }, "evidence": [ { "id": "G3X6E6", "url": "https://omabrowser.org/oma/group/G3X6E6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "G3X6E6", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1258, "end_pos": 1260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1343, "end_pos": 1345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1552, "end_pos": 1554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" }, { "id": "PF25520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like AAA+ ATPase lid", "eco_id": "ECO_0000259", "start_pos": 649, "end_pos": 744, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6E6" }, { "id": "PF25521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like winged helix", "eco_id": "ECO_0000259", "start_pos": 746, "end_pos": 898, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1449 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 1258, "end_pos": 1260 }, { "start_pos": 1343, "end_pos": 1345 }, { "start_pos": 1552, "end_pos": 1554 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 679, "end_pos": 681 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QYT8-1", "uniprot_ac": "F6QYT8", "uniprot_id": "F6QYT8_BOVIN", "mass": { "chemical_mass": 97455.0, "monoisotopic_mass": 97455.0 }, "refseq": {}, "gene_names": [ { "name": "AP1G2", "type": "recommended", "evidence": [ { "id": "F6QYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYT8" } ] } ], "protein_names": [ { "name": "AP-1 complex subunit gamma", "type": "recommended", "evidence": [ { "id": "F6QYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYT8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QYT8", "url": "https://www.uniprot.org/uniprotkb/F6QYT8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AP1G2", "url": "https://www.uniprot.org/uniprotkb/F6QYT8", "locus": { "chromosome": "10", "start_pos": 21389478, "end_pos": 21380687, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007099", "url": "https://www.ensembl.org/id/ENSBTAG00000007099" } ] } } ], "crossref": [ { "id": "F6QYT8", "url": "https://alphafold.ebi.ac.uk/entry/F6QYT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007099", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007099", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "REPNTKK", "url": "https://omabrowser.org/oma/group/REPNTKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MCG2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYT8", "url": "https://www.uniprot.org/uniprotkb/F6QYT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYT8-1", "url": "https://www.uniprot.org/uniprotkb/F6QYT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSNPSSQKLSSEGALLGSPRPVRQSRRLEVVKKILPLNSKSQRPEVRGFKIALQGGPGGAGSHNRGGETEGSDQARTFLGAWTRKRWGESRGVETEARMVASSLKLQDLIQEIRGAKTQAQEREVIQKECAHIRASFRDGDPLHSHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERQDAHLLITNSIKNDLSQGIEAVQGLALCTLSAMGSAEMCRDLAPEVEKLLLQPSPYVRKKAVLTAVHMIRKVPELSDIFLPPCAQLLHERHHGILLGTVTLITELCERSPAALQHFRKVVPQLVHTLRTLVMTGCSAEHSVSGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLKLVQSDHSAVQRHRPTVVECLWEPDASLSRRALELSLALVNSSNVRAMTQELQGFLESCPPDLRADCASGILLAAERFAPTKRWHIDTILRVLTTAGTYVRDDAVANLIQLIGGAQELHAYSVHRLYSALAEDISQQPLVQVAAWCIGEYGDLLLEGTCEETEPLQVEKEEVLALLERVLQSQMSLPATRGYALTALMKLSTRLHGDNNRICQVMSIYGSCQNVELQQRAVEYNALFRKYDHLRAAVLEKMPLVERGGPQVDEEAKESKEVAQLSEAAPLPTETQASKLLDLLDLLDGPSENAQHPPPLDPTPGDTLIHLLDLPCAPRPPAPIPNLKVFEREGLELNLSFVRPPGTPTLLLITVTATNTSGGDVTHFICQAAVPKSFQLQLQAPSGDTVPAQGGPPMTQLLRILNPNKAPLRLKLRLTYDHFGQSVQEIFEVNNLPVETWQ", "length": 884, "header": "tr|F6QYT8-1|F6QYT8_BOVIN Isoform 1 of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G2 PE=3 SV=1 CANONICAL=F6QYT8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCG2/entry", "sequence": { "sequence": "MDSNPSSQKLSSEGALLGSPRPVRQSRRLEVVKKILPLNSKSQRPEVRGFKIALQGGPGGAGSHNRGGETEGSDQARTFLGAWTRKRWGESRGVETEARMVASSLKLQDLIQEIRGAKTQAQEREVIQKECAHIRASFRDGDPLHSHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERQDAHLLITNSIKNDLSQGIEAVQGLALCTLSAMGSAEMCRDLAPEVEKLLLQPSPYVRKKAVLTAVHMIRKVPELSDIFLPPCAQLLHERHHGILLGTVTLITELCERSPAALQHFRKVVPQLVHTLRTLVMTGCSAEHSVSGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLKLVQSDHSAVQRHRPTVVECLWEPDASLSRRALELSLALVNSSNVRAMTQELQGFLESCPPDLRADCASGILLAAERFAPTKRWHIDTILRVLTTAGTYVRDDAVANLIQLIGGAQELHAYSVHRLYSALAEDISQQPLVQVAAWCIGEYGDLLLEGTCEETEPLQVEKEEVLALLERVLQSQMSLPATRGYALTALMKLSTRLHGDNNRICQVMSIYGSCQNVELQQRAVEYNALFRKYDHLRAAVLEKMPLVERGGPQVDEEAKESKEVAQLSEAAPLPTETQASKLLDLLDLLDGPSENAQHPPPLDPTPGDTLIHLLDLPCAPRPPAPIPNLKVFEREGLELNLSFVRPPGTPTLLLITVTATNTSGGDVTHFICQAAVPKVCRRPGLRGSLDTPGEKATK", "length": 838, "header": "tr|A0A3Q1MCG2-1|F6QYT8_BOVIN Computationally mapped isoform of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G2 PE=3 SV=2 CANONICAL=F6QYT8-1" }, "locus": { "chromosome": "10", "start_pos": 21388846, "end_pos": 21380886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078889.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078889.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068515.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068515.2" } ] } }, { "isoform_ac": "F6QYT8-1", "url": "https://www.uniprot.org/uniprotkb/F6QYT8/entry", "sequence": { "sequence": "MDSNPSSQKLSSEGALLGSPRPVRQSRRLEVVKKILPLNSKSQRPEVRGFKIALQGGPGGAGSHNRGGETEGSDQARTFLGAWTRKRWGESRGVETEARMVASSLKLQDLIQEIRGAKTQAQEREVIQKECAHIRASFRDGDPLHSHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERQDAHLLITNSIKNDLSQGIEAVQGLALCTLSAMGSAEMCRDLAPEVEKLLLQPSPYVRKKAVLTAVHMIRKVPELSDIFLPPCAQLLHERHHGILLGTVTLITELCERSPAALQHFRKVVPQLVHTLRTLVMTGCSAEHSVSGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLKLVQSDHSAVQRHRPTVVECLWEPDASLSRRALELSLALVNSSNVRAMTQELQGFLESCPPDLRADCASGILLAAERFAPTKRWHIDTILRVLTTAGTYVRDDAVANLIQLIGGAQELHAYSVHRLYSALAEDISQQPLVQVAAWCIGEYGDLLLEGTCEETEPLQVEKEEVLALLERVLQSQMSLPATRGYALTALMKLSTRLHGDNNRICQVMSIYGSCQNVELQQRAVEYNALFRKYDHLRAAVLEKMPLVERGGPQVDEEAKESKEVAQLSEAAPLPTETQASKLLDLLDLLDGPSENAQHPPPLDPTPGDTLIHLLDLPCAPRPPAPIPNLKVFEREGLELNLSFVRPPGTPTLLLITVTATNTSGGDVTHFICQAAVPKSFQLQLQAPSGDTVPAQGGPPMTQLLRILNPNKAPLRLKLRLTYDHFGQSVQEIFEVNNLPVETWQ", "length": 884, "header": "tr|F6QYT8-1|F6QYT8_BOVIN Isoform 1 of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G2 PE=3 SV=1 CANONICAL=F6QYT8-1" }, "locus": { "chromosome": "10", "start_pos": 21389298, "end_pos": 21380886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055864.3", "url": "https://www.ensembl.org/id/ENSBTAT00000055864.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050701.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050701.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 745, "start_aa": "Thr", "end_pos": 745, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr745", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "B0R024-1", "protein_name": "AP-1 complex subunit gamma", "gene_name": "ap1g2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTPSVRLQEMIRVIRSARTQGEERGIIQKECAEIRAQFRQTDNGERSHSLAKLLYVHMLGYPAHFGQMECVRLIASPRYSEKRIGYLGAMMLLDEKQDASLLITNSIKNDLSHSSQYVQSLALCTLACMGSSEMCRDLAPEIERLLRASTSYIKKKATLCAVHIIRKVPELAELFTPSARSLLSEKNHGVLHGAVVLITELCERNAETLDKFRKAVPELVTIMKGLVTSSYSPEHNVAGISDPFLQVRILRLLRILGHNNDSASDAMNDLLAQVATNTDSSKTAGSAVLYETVLTIMDINSESGLRVLAVNILGRFLLNNDRNIRYISMTSLQKIVQTDHNAVQRHRGTIVDCLKDQDTSVKRRALELSLALVSPVNIRSMMKELLIFLSSCPVELRSQTASGIFNAAERYSPSKRWHIDTILHVLTTAGGDVRDETVPNLIQLITTASELHCYTVHKLYRALVKDISQQSLVQVACWCIGEYGDLLLKGECEEIEPVQVTEDDVLDALETVLQSHMSAPATRGFALTATMKLSTRITDNVDRIRSIVSIYGSCIDLELQQRAVEYNALFKKYDHMRAAVLERMPLMEKNSPGHTNGDSSGEIKEPEPAKTKPVEPILLSEPANQVCDLLDLLGGTDTPVQPSSAPTSTATTTSSADLLDLLGGLEPTPVPAVTVYEKNGVSLKIQCDSQTDTDITVTLIASNSTQNDISNFTLQAAVPKSVQLQMKAPSGNVIAAHGLGQVTQTVLLNNPNKVSLKMRVRVSYSDQGTMLQDTVQIDSFPSPSWNSQPSIGVL", "length": 794 }, "evidence": [ { "id": "F6QYT8", "url": "https://omabrowser.org/oma/group/F6QYT8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZGW2-1", "protein_name": "Junctophilin", "gene_name": "Ap1g2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPIPAPPALIEGSATEVYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQDSGGSDTEPLDEDSPGVYENGLTPSEGSPELPSSPASSHQPWRAPPCRSPLPPGGNWGPFSSPKAWPEEWGGPGEQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSGSLREEEGEDEESLPQLRAPGGSESEPVTTPVLRGLSSRGPDAGCLTEEFEEPAATERPAQPGAANPLVVGAVALLDLSLAFLFSQLLT", "length": 628 }, "evidence": [ { "id": "F6QYT8", "url": "https://omabrowser.org/oma/group/F6QYT8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SS42-1", "protein_name": "AP-1 complex subunit gamma", "gene_name": "AP1G2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVVSSLKLQELIQEIREAKTQAQEREVIQKECAHIRASFRDGDPLHRHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERQDAHLLITNSIKNDLSQGIQAIQGLALCTLSTMGSAEMCRDLANEVEKLLLQPSPYVRKKAVLTAVHMIRKVPELSNLFLPPCAQLLRERHHGILLGTITLITELCERSPAALKHFRKVVPQLVHILRSLVTTGYSTEHSISGVSDPFLQVQILRLLRILGQNHEESSETMNDLLAQVATNTNTSRNAGSAVLFETVLTILDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALMSLLRLVQSDHSAVQRHRPTVVDCLRDPDASLSRRALELSLALVNSSNVRAMTQELQGFLESCPPDLRATCASGILLAAERFAPSKRWHIDTILHVLTTAGAYVRDDAVANLTQLIGGAQELHAYSVRRLYSALAKDISQQPLVQVAAWCIGEYGDLLLEGSCEEAEPLQVEEEEVLALLERVLQSHMSLPATRGYALTALMKLSTRLRGDNNRIRQVVSIYGSCMDVELQQRAVEYNTLFRKYDHMRAAILEKMPLMERGGPQVDEKAKESEEEEAAPNPTEPQASKLLDLLDLLDGPSADAHHPPPLDPTPGGTLINLLDLPCAPPPPAPIPNLRVFEREGLQLNLSFVRPPGTPALLLITVTATNTSAGDVTHFICQAAVPKSFQLQLQAPSGDTVPAQGGLPMTQLLRILNPNKAPLRLKLRLTYNHFGQSVQEIFEVNNLPVETWQ", "length": 781 }, "evidence": [ { "id": "F6QYT8", "url": "https://omabrowser.org/oma/group/F6QYT8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75843-1", "protein_name": "AP-1 complex subunit gamma-like 2", "gene_name": "AP1G2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVPSLKLQDLIEEIRGAKTQAQEREVIQKECAHIRASFRDGDPVHRHRQLAKLLYVHMLGYPAHFGQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKVPELSSVFLPPCAQLLHERHHGILLGTITLITELCERSPAALRHFRKVVPQLVHILRTLVTMGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPTKRWHIDTILHVLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNALAEDISQQPLVQVAAWCIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTALMKLSTRLCGDNNRIRQVVSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVERDGPQADEEAKESKEAAQLSEAAPVPTEPQASQLLDLLDLLDGASGDVQHPPHLDPSPGGALVHLLDLPCVPPPPAPIPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ", "length": 785 }, "evidence": [ { "id": "F6QYT8", "url": "https://omabrowser.org/oma/group/F6QYT8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88512-1", "protein_name": "AP-1 complex subunit gamma-like 2", "gene_name": "Ap1g2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVHSLRLQDLIEEIRGAKTQAQEREVIQKECAQIRASFRDGDPLQRHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERHDSHLLITNSIKNDLSQGNQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKDPELSGIFLPPCTKLLRERHHGIQLGTVTLITELCERNPAALRHFRKVVPQLVQILRTLVTTGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLLETVLTIMAIHSAAGLRVLAVNILGRFLLNNDKNIRYVALTSLLQLVQSDHSAVQRHRSTVVECLQETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPSKRWHIDTILHVLTTAGAHVRDDAVANLTQLIGEAEELHTYSVRRLYSALAEDISQQPLVQVAAWCIGEYGDLLLEGNCEETEPFQVEEEDVLALLEKVLQSHMSLPATRGYAITALMKLSTRLRGDNNRIRQVVSIYGSCVDLELQQRAVEYNTLFQKYDHMRAAILEKMPLVERGDPHVKEGGKEKQTEAQPLEVTAPAPTEPQATKLLDLLDLLGDTSEPLSSGHAQHLPPQTPSPGEALIHLLDLPCTPPPPAPIPSVRVFEREGLQLDLSFMRPLETPALLLVTATTTNSSKEDVTHFVCQAAVPKSFQLQLQAPSGNTIPAQGGLPITQVFRILNPNQAPLRLKLRLTYNHSGQPVQEIFEVDNLPVETWQ", "length": 791 }, "evidence": [ { "id": "F6QYT8", "url": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX65-1", "uniprot_ac": "G3MX65", "uniprot_id": "G3MX65_BOVIN", "mass": { "chemical_mass": 17621.0, "monoisotopic_mass": 17621.0 }, "refseq": {}, "gene_names": [ { "name": "WFDC2", "type": "recommended", "evidence": [ { "id": "G3MX65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX65" } ] } ], "protein_names": [ { "name": "WAP four-disulfide core domain protein 2", "type": "recommended", "evidence": [ { "id": "G3MX65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX65/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX65", "url": "https://www.uniprot.org/uniprotkb/G3MX65" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": 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"Protein Classification", "Other" ] }, { "id": "A0A3Q1MH08", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MH08-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R695", "url": "https://www.uniprot.org/uniprotkb/F6R695", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R695-1", "url": "https://www.uniprot.org/uniprotkb/F6R695-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX65", "url": "https://www.uniprot.org/uniprotkb/G3MX65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX65-1", "url": "https://www.uniprot.org/uniprotkb/G3MX65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPACRLGPLLAALLLGLLLGLPPVTGSIAVKPGECPELEGDANCTKACVLDEDCDDNLKCCQAGCATVCQMPNVLSEWLESRSSTHSGLFGELLAIDALLSWGSSVLRAPALLQERTGGNKPGSCPNVDIAFPQLGLCRDQCQVDSQCPDALKCCVNGCGRVSCVTPVF", "length": 169, "header": "tr|G3MX65-1|G3MX65_BOVIN Isoform 1 of WAP four-disulfide core domain protein 2 OS=Bos taurus OX=9913 GN=WFDC2 PE=1 SV=1 CANONICAL=G3MX65-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MH08-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH08/entry", "sequence": { "sequence": "GRTRSEGTEPGRSLASLSSSIAVKPGECPELEGDANCTKACVLDEDCDDNLKCCQAGCATVCQMPNDKPGSCPNVDIAFPQLGLCRDQCQVDSQCPDALKCCVNGCGRVSCVTPVF", "length": 116, "header": "tr|A0A3Q1MH08-1|G3MX65_BOVIN Computationally mapped isoform of WAP four-disulfide core domain protein 2 OS=Bos taurus OX=9913 GN=WFDC2 PE=1 SV=1 CANONICAL=G3MX65-1" }, "locus": { "chromosome": "13", "start_pos": 74364793, "end_pos": 74360968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077883.2", "url": 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} ] } }, { "isoform_ac": "G3MX65-1", "url": "https://www.uniprot.org/uniprotkb/G3MX65/entry", "sequence": { "sequence": "MPACRLGPLLAALLLGLLLGLPPVTGSIAVKPGECPELEGDANCTKACVLDEDCDDNLKCCQAGCATVCQMPNVLSEWLESRSSTHSGLFGELLAIDALLSWGSSVLRAPALLQERTGGNKPGSCPNVDIAFPQLGLCRDQCQVDSQCPDALKCCVNGCGRVSCVTPVF", "length": 169, "header": "tr|G3MX65-1|G3MX65_BOVIN Isoform 1 of WAP four-disulfide core domain protein 2 OS=Bos taurus OX=9913 GN=WFDC2 PE=1 SV=1 CANONICAL=G3MX65-1" }, "locus": { "chromosome": "13", "start_pos": 74364793, "end_pos": 74360857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066322.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066322.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054125.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054125.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": 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"isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RS94-1", "uniprot_ac": "F6RS94", "uniprot_id": "F6RS94_BOVIN", "mass": { "chemical_mass": 49055.0, "monoisotopic_mass": 49055.0 }, "refseq": { "ac": "NP_001075921", "name": "protein mono-ADP-ribosyltransferase PARP11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075921" }, "gene_names": [ { "name": "PARP11", "type": "recommended", "evidence": [ { "id": "F6RS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ] }, { "name": "PARP11", "type": "synonym", "evidence": [ { "id": "NP_001075921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075921" } ] } ], "protein_names": [ { "name": "Poly [ADP-ribose] polymerase", "type": "recommended", "evidence": [ { "id": "F6RS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS94/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.-", "type": "synonym", "evidence": [ { "id": "F6RS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS94/entry#names_and_taxonomy" } ] }, { "name": "PARP", "type": "synonym", "evidence": [ { "id": "F6RS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS94/entry#names_and_taxonomy" } ] }, { "name": "poly [ADP-ribose] polymerase 11", "type": "synonym", "evidence": [ { "id": "NP_001075921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075921" } ] }, { "name": "protein mono-ADP-ribosyltransferase PARP11", "type": "synonym", "evidence": [ { "id": "NP_001075921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075921" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PARP11", "url": "https://www.uniprot.org/uniprotkb/F6RS94", "locus": { "chromosome": "5", "start_pos": 106146167, "end_pos": 106112418, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000275", "url": "https://www.ensembl.org/id/ENSBTAG00000000275" } ] } } ], "crossref": [ { "id": "F6RS94", "url": "https://alphafold.ebi.ac.uk/entry/F6RS94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000275", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539763", "url": "https://www.ncbi.nlm.nih.gov/gene/539763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539763", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539763", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWNPRIF", "url": "https://omabrowser.org/oma/group/TWNPRIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MRM6", "url": "https://www.orthodb.org/?gene=A0A3Q1MRM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RS94", "url": "https://www.orthodb.org/?gene=F6RS94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45740:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45740:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001075921", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075921", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MRM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MRM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RSM0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RSM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVG6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RS94-1", "url": "https://www.uniprot.org/uniprotkb/F6RS94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCRKYHCLPVNQKIKQSMASWLIEPISLTFIDCLLSGGQLVHTPFVAYKCIITSIHYFRGYSILKEMFHKAEEFLSKTTDSEVDEMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKANPCGSISFTTSKFSYKIDFAGVQFTEKARNVQIFETELCKFYHEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTELPYQLIPLHNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGALFGKGTYFARDAAYSSRFCKDDVKHGNTFQIHGVSLPQRHLFRTHKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPRVFVVFDANQIYPEYLIDFH", "length": 420, "header": "tr|F6RS94-1|F6RS94_BOVIN Isoform 1 of Poly [ADP-ribose] polymerase OS=Bos taurus OX=9913 GN=PARP11 PE=3 SV=1 CANONICAL=F6RS94-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MRM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRM6/entry", "sequence": { "sequence": "MCRKYHCLPVNQKIKQSMASWLIEPISLTFIDCLLSGGQLVHTPFVAYKCIITSIHYFRGYSILKEMFHKAEEFLSKTTDSEVDEMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKANPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTELPYQLIPLHNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGALFGKGTYFARDAAYSSRFCKDDVKHGNTFQIHGVSLPQRHLFRTHKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPRVFVVFDANQIYPEYLIDFH", "length": 397, "header": "tr|A0A3Q1MRM6-1|F6RS94_BOVIN Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Bos taurus OX=9913 GN=PARP11 PE=3 SV=1 CANONICAL=F6RS94-1" }, "locus": { "chromosome": "5", "start_pos": 106142783, "end_pos": 106127212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068193.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068193.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072514.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072514.1" } ] } }, { "isoform_ac": "A0AAA9RSM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSM0/entry", "sequence": { "sequence": "VRQVAHVSEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTELPYQLIPLHNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGALFGKGTYFARDAAYSSRFCKDDVKHGNTFQIHGVSLPQRHLFRTHKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPRVFVVFDANQIYPEYLIDFH", "length": 257, "header": "tr|A0AAA9RSM0-1|F6RS94_BOVIN Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Bos taurus OX=9913 GN=PARP11 PE=3 SV=1 CANONICAL=F6RS94-1" }, "locus": { "chromosome": "5", "start_pos": 106142783, "end_pos": 106131662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123439.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123439.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075636.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075636.1" } ] } }, { "isoform_ac": "A0AAA9SVG6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVG6/entry", "sequence": { "sequence": "MWEANPEMFHKAEEFLSKTTDSEVDEMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKANPCGSISFTTSKFSYKIDFAGVQFTEKARNVQIFETELCKFYHEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTELPYQLIPLHNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGALFGKGTYFARDAAYSSRFCKDDVKHGNTFQIHGVSLPQRHLFRTHKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPRVFVVFDANQIYPEYLIDFH", "length": 361, "header": "tr|A0AAA9SVG6-1|F6RS94_BOVIN Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Bos taurus OX=9913 GN=PARP11 PE=3 SV=1 CANONICAL=F6RS94-1" }, "locus": { "chromosome": "5", "start_pos": 106142783, "end_pos": 106112656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114891.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114891.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089316.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089316.1" } ] } }, { "isoform_ac": "F6RS94-1", "url": "https://www.uniprot.org/uniprotkb/F6RS94/entry", "sequence": { "sequence": "MCRKYHCLPVNQKIKQSMASWLIEPISLTFIDCLLSGGQLVHTPFVAYKCIITSIHYFRGYSILKEMFHKAEEFLSKTTDSEVDEMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKANPCGSISFTTSKFSYKIDFAGVQFTEKARNVQIFETELCKFYHEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTELPYQLIPLHNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGALFGKGTYFARDAAYSSRFCKDDVKHGNTFQIHGVSLPQRHLFRTHKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPRVFVVFDANQIYPEYLIDFH", "length": 420, "header": "tr|F6RS94-1|F6RS94_BOVIN Isoform 1 of Poly [ADP-ribose] polymerase OS=Bos taurus OX=9913 GN=PARP11 PE=3 SV=1 CANONICAL=F6RS94-1" }, "locus": { "chromosome": "5", "start_pos": 106142783, "end_pos": 106127212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049732.4", "url": "https://www.ensembl.org/id/ENSBTAT00000049732.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046585.4", "url": "https://www.ensembl.org/id/ENSBTAP00000046585.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:539763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539763", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTL9-1", "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Parp11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFHKTEEFFPKKTESDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "length": 331 }, "evidence": [ { "id": "F6RS94", "url": "https://omabrowser.org/oma/group/F6RS94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7GH89-1", "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "Parp11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNWPFHRAQMFHKTEEFFPKKTESDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNTEVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSVQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "length": 340 }, "evidence": [ { "id": "F6RS94", "url": "https://omabrowser.org/oma/group/F6RS94/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CFF0-1", "protein_name": "Protein mono-ADP-ribosyltransferase PARP11", "gene_name": "Parp11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHKTEEFFPKKTDSDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "length": 331 }, "evidence": [ { "id": "F6RS94", "url": "https://omabrowser.org/oma/group/F6RS94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NR21-4", "protein_name": "Protein mono-ADP-ribosyltransferase PARP11", "gene_name": "PARP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH", "length": 338 }, "evidence": [ { "id": "F6RS94", "url": "https://omabrowser.org/oma/group/F6RS94/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "protein auto-ADP-ribosylation", "id": "GO:0070213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070213", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" }, { "name": "NAD+-protein mono-ADP-ribosyltransferase activity", "id": "GO:1990404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990404", "evidence": [ { "database": "UniProtKB", "id": "F6RS94", "url": "https://www.uniprot.org/uniprotkb/F6RS94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RS94-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 420, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RS94-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RS94" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS94" }, { "id": "PS51059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PARP catalytic", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 420, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS94" }, { "id": "PS50918", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WWE", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 168, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX46-1", "uniprot_ac": "G3MX46", "uniprot_id": "G3MX46_BOVIN", "mass": { "chemical_mass": 257055.0, "monoisotopic_mass": 257055.0 }, "refseq": { "ac": "XP_005219445", "name": "protein capicua homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219445" }, "gene_names": [ { "name": "CIC", "type": "recommended", "evidence": [ { "id": "G3MX46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ] }, { "name": "CIC", "type": "synonym", "evidence": [ { "id": "XP_005219445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219445" } ] } ], "protein_names": [ { "name": "Protein capicua homolog", "type": "recommended", "evidence": [ { "id": "G3MX46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX46/entry#names_and_taxonomy" } ] }, { "name": "protein capicua homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005219445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219445" } ] } ], "function": [ { "annotation": "Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.", "evidence": [ { "database": "UniProtKB", "id": "E1B8E2", "url": "https://www.uniprot.org/uniprotkb/E1B8E2#function" }, { "database": "UniProtKB", "id": "ARBA00053962", "url": "https://www.uniprot.org/uniprotkb/ARBA00053962#function" }, { "database": "UniProtKB", "id": "A0A3Q1MSI7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSI7#function" }, { "database": "UniProtKB", "id": "A0AAA9RWC2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC2#function" }, { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CIC", "url": "https://www.uniprot.org/uniprotkb/G3MX46", "locus": { "chromosome": "18", "start_pos": 50982136, "end_pos": 51009598, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019785", "url": "https://www.ensembl.org/id/ENSBTAG00000019785" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019785", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538483", "url": "https://www.ncbi.nlm.nih.gov/gene/538483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538483", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EPEEAIW", "url": "https://omabrowser.org/oma/group/EPEEAIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1B8E2", "url": "https://www.orthodb.org/?gene=E1B8E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MX46", "url": "https://www.orthodb.org/?gene=G3MX46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13059", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13059", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13059:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13059:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005219445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSI7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWC2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWC2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8E2", "url": "https://www.uniprot.org/uniprotkb/E1B8E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8E2-1", "url": "https://www.uniprot.org/uniprotkb/E1B8E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX46-1", "url": "https://www.uniprot.org/uniprotkb/G3MX46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPMKKACTSLPGSGSSGKSPPATRAKALRRRGAGEGDKPEEEDDEAQQQQPGPEEAEEGEEEEAEQGPRAEGLPPELQADDPAPGPAEEPKVEGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSGSSAAVGAPEEQARTPEEAGALGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGLGPWTPGSTSGGYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFHGDRALTFYEGVPGGGVDVVLDATPPPGALAVGTAVCTCVEPGMAAYREGVVVEVATKPAAYKVRFGPGPSSQLGPAALPQPPQPPHREPEDAVWVARSSLRLLRPPWEPEALPRKPPAGPEEEQAEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGACEEGEEKHPPALGTPALLPLPPQLLSPPPKSPAFAGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGAAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGPGGAGRPAGVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGALGAPGAAGGGAAPDFPKNDSLDAGVDSVSHTPAPSAPAGFRAVSPAMPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEVGTGSEARAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTFGLASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGTGNADPGRPPGATCPESPGPGPPHTLGVVEPGKGPPPTTEDEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKEPRERSMSETGTAAAPGVSSELLSVTAQTLLSSDTKAPGSSSCGAERLHAVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYAGPKPSTQYGTPGHFAAPGEGGTLAASGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGSKGFGRKVFSPVIRSSFTHCRPSLDPEPPGPPDPPAGFGKGYGPTSSASSPAASSSSATTSFPLGSGTFKAQESGQGSTTGPLRPPPPGTGGPATPSKATRFLPTDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGGVLQTLVLPSNKEEREGSGARVPSAPAPSLAYGAPATPLSRPAATMVTNVVRPVSSTPVPIASKPFPAPSRAEASPGDTAGARTEAATGSRALGGSPLGVSLVYSDKKSGAATSTAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGGPGSGAAAGSGASAGSGPNGPMPLGILQPGPLGKAGGITQVQYILPTLPQQLQVAPAPGTKAAAPGGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLATPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPAPLPGPASQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQPGTVTSYGPTSSVTLGFTSLGPSGPAFVQPLLSGQAPLLAPGQVGVSPVPSPQLPPTCAAASGPVITAFYPGSPIPTSSAPLAQPSQAPPGLVYTVATSTTPPAAPILPKGPPAPTAATPAPASPFPSATGSMTYSLVAPKAQRPTPKAPQKVKAAIASIPVGSFEAGAPGRPGPAPRQPLEPGPAREPPASESELEGRPATPAPPLPHETWTPTARSSPPLPPPAEEQASTKGPETMATKFPSSSSDWRVPGLGLESRGEPPTPPSPALAPAPAPGSSSGSSEGSSGRAAGDAPERKEAAGAGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPSEQPPGAEAPLPGPPPTGTAAAPVPTPSPAGGPDPTSPGSDSGTAPAAPPLPPPPEPGPGQPGWEGPPQPSPPASGSSTAATGR", "length": 2509, "header": "tr|G3MX46-1|G3MX46_BOVIN Isoform 1 of Protein capicua homolog OS=Bos taurus OX=9913 GN=CIC PE=4 SV=2 CANONICAL=G3MX46-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MSI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSI7/entry", "sequence": { "sequence": "MKPMKKACTSLPGSGSSGKSPPATRAKALRRRGAGEGDKPEEEDDEAQQQQPGPEEAEEGEEEEAEQGPRAEGLPPELQADDPAPGPAEEPKVEGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSGSSAAVGAPEEQARTPEEAGALGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGLGPWTPGSTSGGYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFHGDRALTFYEGVPGGGVDVVLDATPPPGALAVGTAVCTCVEPGMAAYREGVVVEVATKPAAYKVRFGPGPSSQLGPAALPQPPQPPHREPEDAVWVARSSLRLLRPPWEPEALPRKPPAGPEEEQAEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGACEEGEEKHPPALGTPALLPLPPQLLSPPPKSPAFAGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGAAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGPGGAGRPAGVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGALGAPGAAGGGAAPDFPKNDSLDAGVDSVSHTPAPSAPAGFRAVSPAMPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEVGTGSEARAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTFGLASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGTGNADPGRPPGATCPESPGPGPPHTLGVVEPGKGPPPTTEDEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKEPRERSMSETGTAAAPGVSSELLSVTAQTLLSSDTKAPGSSSCGAERLHAVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYAGPKPSTQYGTPGHFAAPGEGGTLAASGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGSKGFGRKVFSPVIRSSFTHCRPSLDPEPPGPPDPPAGFGKGYGPTSSASSPAASSSSATTSFPLGSGTFKAQESGQGSTTGPLRPPPPGTGGPATPSKATRFLPTDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGGVLQTLVLPSNKEEREGSGARVPSAPAPSLAYGAPATPLSRPAATMVTNVVRPVSSTPVPIASKPFPAPSRAEASPGDTAGARTEAATGSRALGGSPLGVSLVYSDKKSGAATSTAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGGPGSGAAAGSGASAGSGPNGPMPLGILQPGPLGKAGGITQVQYILPTLPQQLQVAPAPGTKAAAPGGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLATPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPAPLPGPASQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQPGTVTSYGPTSSVTLGFTSLGPSGPAFVQPLLSGQAPLLAPGQVGVSPVPSPQLPPTCAAASGPVITAFYPGSPIPTSSAPLAQPSQAPPGLVYTVATSTTPPAAPILPKGPPAPTAATPAPASPFPSATGSMTYSLVAPKAQRPTPKAPQKVKAAIASIPVGSFEAGAPGRPGPAPRQPLEPGPAREPPASESELEGRPATPAPPLPHETWTPTARSSPPLPPPAEEQASTKGPETMATKFPSSSSDWRVPGLGLESRGEPPTPPSPALAPAPAPGSSSGSSEGSSGRAAGDAPERKEAAGAGKKVKVRPPPLKKTFDSVDKVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPSEQPPGAEAPLPGPPPTGTAAAPVPTPSPAGGPDPTSPGSDSGTAPAAPPLPPPPEPGPGQPGWEGPPQPSPPASGSSTAATGR", "length": 2508, "header": "tr|A0A3Q1MSI7-1|G3MX46_BOVIN Computationally mapped isoform of Protein capicua homolog OS=Bos taurus OX=9913 GN=CIC PE=4 SV=2 CANONICAL=G3MX46-1" }, "locus": { "chromosome": "18", "start_pos": 51006281, "end_pos": 50982982, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075541.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075541.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057470.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057470.2" } ] } }, { "isoform_ac": "A0AAA9RWC2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC2/entry", "sequence": { "sequence": "MKPMKKACTSLPGSGSSGKSPPATRAKALRRRGAGEGDKPEEEDDEAQQQQPGPEEAEEGEEEEAEQGPRAEGLPPELQADDPAPGPAEEPKVEGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSGSSAAVGAPEEQARTPEEAGALGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGLGPWTPGSTSGGYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFHGDRALTFYEGVPGGGVDVVLDATPPPGALAVGTAVCTCVEPGMAAYREGVVVEVATKPAAYKVRFGPGPSSQLGPAALPQPPQPPHREPEDAVWVARSSLRLLRPPWEPEALPRKPPAGPEEEQAEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGACEEGEEKHPPALGTPALLPLPPQLLSPPPKSPAFAGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGAAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGPGGAGRPAGVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGALGAPGAAGGGAAPDFPKNDSLDAGVDSVSHTPAPSAPAGFRAVSPAMPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEVGTGSEARAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTFGLASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGTGNADPGRPPGATCPESPGPGPPHTLGVVEPGKGPPPTTEDEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKEPRERSMSETGTAAAPGVSSELLSVTAQTLLSSDTKAPGSSSCGAERLHAVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYAGPKPSTQYGTPGHFAAPGEGGTLAASGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGSKGFGRKVFSPVIRSSFTHCRPSLDPEPPGPPDPPAGFGKGYGPTSSASSPAASSSSATTSFPLGSGTFKAQESGQGSTTGPLRPPPPGTGGPATPSKATRFLPTDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGGVLQTLVLPSNKEEREGSGARVPSAPAPSLAYGAPATPLSRPAATMVTNVVRPVSSTPVPIASKPFPAPSRAEASPGDTAGARTEAATGSRALGGSPLGVSLVYSDKKSGAATSTAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGGPGSGAAAGSGASAGSGPNGPMPLGILQPGPLGKAGGITQVQYILPTLPQQLQVAPAPGTKAAAPGGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLATPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPAPLPGPASQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQPGTVTSYGPTSSVTLGFTSLGPSGPAFVQPLLSGQAPLLAPGQVGVSPVPSPQLPPTCAAASGPVITAFYPGSPIPTSSAPLAQPSQAPPGLVYTVATSTTPPAAPILPKGPPAPTAATPAPASPFPSATGSMTYSLVAPKAQRPTPKAPQKVKAAIASIPVGSFEAGAPGRPGPAPRQPLEPGPAREPPASESELEGRPATPAPPLPHETWTPTARSSPPLPPPAEEQASTKGPETMATKFPSSSSDWRVPGLGLESRGEPPTPPSPALAPAPAPGSSSGSSEGSSGRAAGDAPERKEAAGAGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTGRPGLGPRGPHLAQAQDEAALQL", "length": 2322, "header": "tr|A0AAA9RWC2-1|G3MX46_BOVIN Computationally mapped isoform of Protein capicua homolog OS=Bos taurus OX=9913 GN=CIC PE=4 SV=1 CANONICAL=G3MX46-1" }, "locus": { "chromosome": "18", "start_pos": 51006281, "end_pos": 50984226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114722.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114722.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077723.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077723.1" } ] } }, { "isoform_ac": "E1B8E2-1", "url": "https://www.uniprot.org/uniprotkb/E1B8E2/entry", "sequence": { "sequence": "MYSAHRPLVPASGAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGTGNADPGRPPGATCPESPGPGPPHTLGVVEPGKGPPPTTEDEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKEPRERSMSETGTAAAPGVSSELLSVTAQTLLSSDTKAPGSSSCGAERLHAVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYAGPKPSTQYGTPGHFAAPGEGGTLAASGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGSKGFGRKVFSPVIRSSFTHCRPSLDPEPPGPPDPPAGFGKGYGPTSSASSPAASSSSATTSFPLGSGTFKAQESGQGSTTGPLRPPPPGTGGPATPSKATRFLPTDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGGVLQTLVLPSNKEEREGSGARVPSAPAPSLAYGAPATPLSRPAATMVTNVVRPVSSTPVPIASKPFPAPSRAEASPGDTAGARTEAATGSRALGGSPLGVSLVYSDKKSGAATSTAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGGPGSGAAAGSGASAGSGPNGPMPLGILQPGPLGKAGGITQVQYILPTLPQQLQVAPAPGTKAAAPGGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLATPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPAPLPGPASQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQPGTVTSYGPTSSVTLGFTSLGPSGPAFVQPLLSGQAPLLAPGQVGVSPVPSPQLPPTCAAASGPVITAFYPGSPIPTSSAPLAQPSQAPPGLVYTVATSTTPPAAPILPKGPPAPTAATPAPASPFPSATGSMTYSLVAPKAQRPTPKAPQKVKAAIASIPVGSFEAGAPGRPGPAPRQPLEPGPAREPPASESELEGRPATPAPPLPHETWTPTARSSPPLPPPAEEQASTKGPETMATKFPSSSSDWRVPGLGLESRGEPPTPPSPALAPAPAPGSSSGSSEGSSGRAAGDAPERKEAAGAGKKVKVRPPPLKKTFDSVDKVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPSEQPPGAEAPLPGPPPTGTAAAPVPTPSPAGGPDPTSPGSDSGTAPAAPPLPPPPEPGPGQPGWEGPPQPSPPASGSSTAATGR", "length": 1602, "header": "tr|E1B8E2-1|G3MX46_BOVIN Computationally mapped isoform of Protein capicua homolog OS=Bos taurus OX=9913 GN=CIC PE=4 SV=4 CANONICAL=G3MX46-1" }, "locus": { "chromosome": "18", "start_pos": 50993810, "end_pos": 50982982, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026362.8", "url": "https://www.ensembl.org/id/ENSBTAT00000026362.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026362.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026362.7" } ] } }, { "isoform_ac": "G3MX46-1", "url": "https://www.uniprot.org/uniprotkb/G3MX46/entry", "sequence": { "sequence": "MKPMKKACTSLPGSGSSGKSPPATRAKALRRRGAGEGDKPEEEDDEAQQQQPGPEEAEEGEEEEAEQGPRAEGLPPELQADDPAPGPAEEPKVEGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSGSSAAVGAPEEQARTPEEAGALGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGLGPWTPGSTSGGYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFHGDRALTFYEGVPGGGVDVVLDATPPPGALAVGTAVCTCVEPGMAAYREGVVVEVATKPAAYKVRFGPGPSSQLGPAALPQPPQPPHREPEDAVWVARSSLRLLRPPWEPEALPRKPPAGPEEEQAEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGACEEGEEKHPPALGTPALLPLPPQLLSPPPKSPAFAGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGAAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGPGGAGRPAGVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGALGAPGAAGGGAAPDFPKNDSLDAGVDSVSHTPAPSAPAGFRAVSPAMPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEVGTGSEARAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTFGLASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGTGNADPGRPPGATCPESPGPGPPHTLGVVEPGKGPPPTTEDEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKEPRERSMSETGTAAAPGVSSELLSVTAQTLLSSDTKAPGSSSCGAERLHAVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYAGPKPSTQYGTPGHFAAPGEGGTLAASGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGSKGFGRKVFSPVIRSSFTHCRPSLDPEPPGPPDPPAGFGKGYGPTSSASSPAASSSSATTSFPLGSGTFKAQESGQGSTTGPLRPPPPGTGGPATPSKATRFLPTDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGGVLQTLVLPSNKEEREGSGARVPSAPAPSLAYGAPATPLSRPAATMVTNVVRPVSSTPVPIASKPFPAPSRAEASPGDTAGARTEAATGSRALGGSPLGVSLVYSDKKSGAATSTAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGGPGSGAAAGSGASAGSGPNGPMPLGILQPGPLGKAGGITQVQYILPTLPQQLQVAPAPGTKAAAPGGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLATPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPAPLPGPASQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQPGTVTSYGPTSSVTLGFTSLGPSGPAFVQPLLSGQAPLLAPGQVGVSPVPSPQLPPTCAAASGPVITAFYPGSPIPTSSAPLAQPSQAPPGLVYTVATSTTPPAAPILPKGPPAPTAATPAPASPFPSATGSMTYSLVAPKAQRPTPKAPQKVKAAIASIPVGSFEAGAPGRPGPAPRQPLEPGPAREPPASESELEGRPATPAPPLPHETWTPTARSSPPLPPPAEEQASTKGPETMATKFPSSSSDWRVPGLGLESRGEPPTPPSPALAPAPAPGSSSGSSEGSSGRAAGDAPERKEAAGAGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPSEQPPGAEAPLPGPPPTGTAAAPVPTPSPAGGPDPTSPGSDSGTAPAAPPLPPPPEPGPGQPGWEGPPQPSPPASGSSTAATGR", "length": 2509, "header": "tr|G3MX46-1|G3MX46_BOVIN Isoform 1 of Protein capicua homolog OS=Bos taurus OX=9913 GN=CIC PE=4 SV=2 CANONICAL=G3MX46-1" }, "locus": { "chromosome": "18", "start_pos": 51006281, "end_pos": 50982982, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064364.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064364.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054105.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054105.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1437, "start_aa": "Thr", "end_pos": 1437, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1437", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1487, "start_aa": "Thr", "end_pos": 1487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1487", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1759, "start_aa": "Thr", "end_pos": 1759, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1759", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1783, "start_aa": "Thr", "end_pos": 1783, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1783", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1828, "start_aa": "Thr", "end_pos": 1828, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1828", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1873, "start_aa": "Thr", "end_pos": 1873, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1873", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1935, "start_aa": "Thr", "end_pos": 1935, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1935", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2041, "start_aa": "Thr", "end_pos": 2041, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2041", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2044, "start_aa": "Thr", "end_pos": 2044, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2044", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2127, "start_aa": "Thr", "end_pos": 2127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2127", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2189, "start_aa": "Thr", "end_pos": 2189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2189", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2309, "start_aa": "Thr", "end_pos": 2309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2309", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2451, "start_aa": "Thr", "end_pos": 2451, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2451", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2461, "start_aa": "Thr", "end_pos": 2461, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2461", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 408, "start_aa": "Thr", "end_pos": 408, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr408", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:538483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538483", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A853-1", "protein_name": "Protein capicua homolog", "gene_name": "Cic", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYSAHRPLIPASGAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGTGGADPGRPPGATCPESPGPGPPLTLGGVDPGKSLPPTTEEEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPASLGLAGGHKETRERSMSETGTAAAPGVSSELLSAAAQTLLSSDTKAPGSGPCGAERLHAVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPTSFSGPKPSPQYGAPGSFAAPGEGGNLATSGRPPLLPSRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDSFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPTLDPEPPGPPDPPAAFSKGYGPTPSSSSSPASTSVSVSTSFSLGSGTFKTQESGQGSTAVPLRPPPPGAGGPTTPSKATRFLPTDSATFRRKRPESVGSLEAPGSSVIAAPPSGGGNILQTLVLPPSKEDREGTRVPSAPAPSLAYGAPAAPLCRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASSNDTVGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPASPAVQFIAQGAPGSATPAGSGASAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTAGIPILQSVPSAPPPKAQSVSPVQATPSGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSSPFSVPVQNGAQQPSKIIQLTPVPVSTPSGLVPPLSPATMPGPTSQPQKVLLPSSTRITYVQSAGGHTLPLGTSSACSQTGTVTSYGPASSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACTAPGGPVITAFYPGSPAPTSAPLGPPSQAPPSLVYTVATSTTPPAAAILPKGPPASATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFESGTTGRTGPTPRQSLDSGVAREPAAPESELEGQPTPPAPPPPTETWPPTARSSPPPPLPAEERPGTKGPETASKFPSSSSDWRVPGLGLESRGEPPTPPSPAPAPATGPSGSSSGSSEGSSGRAAGDTPERKEVTSSGKKMKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTETEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEASLPGPPPTGMAATPVPTPSPAGGPDPTSPGSDSGTAQVAPPLPPPPEPGPGQPGWEGAPQPSPPPSGPSTAATGR", "length": 1607 }, "evidence": [ { "id": "G3MX46", "url": "https://omabrowser.org/oma/group/G3MX46/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q924A2-4", "protein_name": "Protein capicua homolog", "gene_name": "Cic", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPMKKACPGLAGSASGSKSPPATRAKALRRRGAGEGDKPEEEEEAQPQEQAGPEEAEEGEEEEAERDPGAEGTHPELQPNDPTPGLTEDPKGDGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGTGNVGVVGAPEERERTPEDASALGVPPRPPTSTRSSSTDTASEHSADLEDEPPEACGPGPWPSTGTSEGYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYEGVPGGGVDVVLDVTPPPGALMVGTAVCTCVEPGVAAYREGVVVEVATKPAAYKVRLSPGPSSHAGPPGTLPQAQQTLHREPEEAVWVTRSSLRLLRPPWEPGALLRKHPAGPEEEQAEPGPALPPCPSSVEPKQPEDAEVSNISFGSNLGTRCEEGEEKHPPSLGTPVLLPLPPPQLLSPPPKSPAFGGPGRPSEQPSPCQEGSQGGSRSSSVASLEKGAAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGPGGTGRPAGVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGTLGASGAGGGGAAPDFPKSDSLDSGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEVGTAGEARAGGPGRSCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTLGLASSPFQPVAFHPSPAALLPVLVPSSYPSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGTGGADPGRPPGAVCPESPGPGPPLTLGGVDPGKSLPPTTEEEAPGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPASLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKVPGSGPCGAERLHAVGAPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSPQYGAPGSFAAPGEGGTLATSGRPPLLPSRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDSFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPTLDPEPPGPPDPPAAFSKGYGPTPSSSSSPASTSVSVSTSFSLGSGTFKTQESGQGSTAVPLRPPPPGAGGPATPSKATRFPPTDSATFRRKRPESVGSLEAPGPSVIAAPPSGGGNLLQTLVLPPSKEDREGTRVPSAPAPPLAYGAPAAPLCRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASSNDIAGARTEMGTGSRVPGGSPMGVSLVYSDKKSAAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPASPAVQFIAQGAPGSATPAGSGASTGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTAGIPILQSVPSAPPPKAQSVSPVQATPSGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSSPFSVPVQNGAQQPSKIIQLTPVPVSTPSGLVPPLSPATMPGPTSQPQKVLLPSSTRITYVQSAGGHTLPLGTSSACSQTGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSGQAPLLAPGQVGVSPVPSPQLPPACTASGGPVITAFYPGSPAPTSAPLGPPSQAPPSLVYTVATSTTPPAATILPKGPPASATATPAPTSPFPSATGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFESGTTGRPGSTPRQSSDSGVAREPAAPESELEGQPTPPAPPPPTETWPPTARSSPPPPLPAEERPGTKGPETASKFPSSSSDWRVPGLGLESRGEPPTPPSPAPATGPSGSSSGSSEGSSGRAAGDTPERKEVTSSGKKMKVRPPPLKKTFDSVDKVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTETEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPGPPPTGMAATPVPTPSPAGGPDPTSPGSDSGTAQVAPPLPPPPEPGPGQPGWEGAPQPSPPPSGPSTAATGR", "length": 2510 }, "evidence": [ { "id": "G3MX46", "url": "https://omabrowser.org/oma/group/G3MX46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96RK0-1", "protein_name": "Protein capicua homolog", "gene_name": "CIC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPMKKACTGLSGPGSGSKSPPATRAKALRRRGAGEGDKPEEEDDEAQQPQPQSGPEEAEEGEEEEAERGPGAEGPPLELHPGDPAPGPAEDPKGDGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSSGVAGAPEERVRTPEEASGLGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGPGPWPPGSTSGSYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYEGVPGAGVDVVLDATPPPGALVVGTAVCTCVEPGVAAYREGVVVEVATKPAAYKVRLSPGPSSQPGLPGSLPQPPQPLHREPEEAVWVARSSLRLLRPPWEPETMLRKPPTGPEEEQAEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGTHCEEGEEKHPPALGTPALLPLPPPQLLSPPPKSPAFVGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGTAPAARARTPLTAAQQKYKKGDVVCTPSGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGPGGAGRPAAVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGALGAPGAGGGGAAPDFPKSDSLDSGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEVGTAGEVRAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPAFGLASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR", "length": 2517 }, "evidence": [ { "id": "G3MX46", "url": "https://omabrowser.org/oma/group/G3MX46/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "G3MX46", "url": "https://www.uniprot.org/uniprotkb/G3MX46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2297, "end_pos": 2299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MX46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX46" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 1106, "end_pos": 1174, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 408, 1437, 1487, 1759, 1783, 1828, 1873, 1935, 2041, 2044, 2127, 2189, 2309, 2451, 2461 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1133, "end_pos": 1135 }, { "start_pos": 2297, "end_pos": 2299 }, { "start_pos": 640, "end_pos": 642 }, { "start_pos": 645, "end_pos": 647 }, { "start_pos": 699, "end_pos": 701 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 975, "end_pos": 977 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 15 }, { "field": "total_sites", "count": 15 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 15 }, { "field": 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} ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZ46-1", "uniprot_ac": "G3MZ46", "uniprot_id": "G3MZ46_BOVIN", "mass": { "chemical_mass": 125097.0, "monoisotopic_mass": 125097.0 }, "refseq": { "ac": "XP_005211924", "name": "atos homolog protein A isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211924" }, "gene_names": [ { "name": "ATOSA", "type": "recommended", "evidence": [ { "id": "G3MZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ46" } ] }, { "name": "ATOSA", "type": "synonym", "evidence": [ { "id": "XP_005211924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211924" } ] } ], "protein_names": [ { "name": "Atos homolog protein A", "type": "recommended", "evidence": [ { "id": "G3MZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ46/entry#names_and_taxonomy" } ] }, { "name": "atos homolog protein A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005211924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211924" } ] } ], "function": [ { "annotation": "Transcription regulator that syncronizes transcriptional and translational programs to promote macrophage invasion of tissues.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9U1P0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1P0#function" }, { "database": "UniProtKB", "id": "ARBA00037191", "url": "https://www.uniprot.org/uniprotkb/ARBA00037191#function" }, { "database": "UniProtKB", "id": "G3MZ46", "url": "https://www.uniprot.org/uniprotkb/G3MZ46#function" }, { "database": "UniProtKB", "id": "A0A3Q1N2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2Y2#function" }, { "database": "UniProtKB", "id": "F1MD00", "url": "https://www.uniprot.org/uniprotkb/F1MD00#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ46", "url": "https://www.uniprot.org/uniprotkb/G3MZ46" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATOSA", "url": "https://www.uniprot.org/uniprotkb/G3MZ46", "locus": { "chromosome": "10", "start_pos": 57808463, "end_pos": 57723461, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024958", "url": "https://www.ensembl.org/id/ENSBTAG00000024958" } ] } } ], "crossref": [ { "id": "G3MZ46", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024958", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024958", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "522864", "url": "https://www.ncbi.nlm.nih.gov/gene/522864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522864", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR13199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13199:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005211924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N2Y2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N2Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1P0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1P0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MD00", "url": "https://www.uniprot.org/uniprotkb/F1MD00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MD00-1", "url": "https://www.uniprot.org/uniprotkb/F1MD00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ46", "url": "https://www.uniprot.org/uniprotkb/G3MZ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ46-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPDREAAHFSLMIKGPSLVVINYTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPITTKHECSDKLAQCRQARRTRSEVALLWKNNLPIMVEVMLLPDCCYSDDGPTTEGIDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGATPRNILYRISAADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRIQEHELKTHQHRNSTEADHCSTDSSQRVCSKQTWTMAPESIILHAKNGTTPEYSAAVKNVKLYPGIGSKSDYGTSQGNILGFSNIGEKKSHETSVRTLKSFSVVDSSDSSHQSSWQSVGETNPLIGSLIQERQEVIARIAQHLIHCDPSTSHVSEHPLNMQESSSLNSKLFRVSQENESVRRCKETFSVSFGSPELTSSEDTSEGKIRVKPETPRNGTYISNGLHSRQSVGETNPLISSLLQERQDIIARIAQHLEHIDPMASHMPRQSFNMQDSSSVPSKVFRSSYEDKNLLKKNKDDTSVSISNTKFSLLDDISEGKNSISNKYFSSFNCNSKVKPSLQPQIRRNLYKDNPSEIQGTFQQTQNKATGLTTPSNISHCKENNFDLTIRLENTCSECQFKKQEINNEIDKEYSNCNSIDKQVCTNKYKDKIINENYNPESFINHQCDNSKKNDSKVKVTVLEMSGYLSKHENECSNKDPKRPKPCEQNTQLNSIENYLIKDSEGFKCKKLDQLRNEQDKKEDPIDENSQNCSQRKNIKDCLSTCERLKNKEVLQRTIPLRHSSVWQKHNFHSLDGTSTRAFHPRTGLPLLSSPVPQRKAQSGCFDLDSSFLHLKSLSSRSPQPCLNIEDDPDIHEKPLLSSSAPPVTSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGVFCPTHLTLPVEVSFYSVSEDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEMKRSVNKENIRHTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1106, "header": "tr|G3MZ46-1|G3MZ46_BOVIN Isoform 1 of Atos homolog protein A OS=Bos taurus OX=9913 GN=ATOSA PE=3 SV=3 CANONICAL=G3MZ46-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N2Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2Y2/entry", "sequence": { "sequence": 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"length": 1095, "header": "tr|A0A3Q1N2Y2-1|G3MZ46_BOVIN Computationally mapped isoform of Atos homolog protein A OS=Bos taurus OX=9913 GN=ATOSA PE=3 SV=3 CANONICAL=G3MZ46-1" }, "locus": { "chromosome": "10", "start_pos": 57807459, "end_pos": 57749333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085863.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085863.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063702.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063702.3" } ] } }, { "isoform_ac": "A0AAA9U1P0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1P0/entry", "sequence": { "sequence": 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"length": 1088, "header": "tr|A0AAA9U1P0-1|G3MZ46_BOVIN Computationally mapped isoform of Atos homolog protein A OS=Bos taurus OX=9913 GN=ATOSA PE=3 SV=2 CANONICAL=G3MZ46-1" }, "locus": { "chromosome": "10", "start_pos": 57807459, "end_pos": 57723972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091153.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091153.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103156.2", "url": "https://www.ensembl.org/id/ENSBTAP00000103156.2" } ] } }, { "isoform_ac": "F1MD00-1", "url": "https://www.uniprot.org/uniprotkb/F1MD00/entry", "sequence": { "sequence": "MLFKHQQNCQYTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPITTKHECSDKLAQCRQARRTRSEVALLWKNNLPIMVEVMLLPDCCYSDDGPTTEGIDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGATPRNILYRISAADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRIQEHELKTHQHRNSTEADHCSTDSSQRVCSKQTWTMAPESIILHAKNGTTPEYSAAVKNVKLYPGIGSKSDYGTSQGNILGFSNIGEKKSHETSVRTLKSFSVVDSSDSSHQSSWQSVGETNPLIGSLIQERQEVIARIAQHLIHCDPSTSHVSEHPLNMQESSSLNSKLFRVSQENESVRRCKETFSVSFGSPELTSSEDTSEGKIRVKPETPRNGTYISNGLHSRQSVGETNPLISSLLQERQDIIARIAQHLEHIDPMASHMPRQSFNMQDSSSVPSKVFRSSYEDKNLLKKNKDDTSVSISNTKFSLLDDISEGKNSISNKYFSSFNCNSKVKPSLQPQIRRNLYKDNPSEIQGTFQQTQNKATGLTTPSNISHCKENNFDLTIRLENTCSECQFKKQEINNEIDKEYSNCNSIDKQVCTNKYKDKIINENYNPESFINHQCDNSKKNDSKVKVTVLEMSGYLSKHENECSNKDPKRPKPCEQNTQLNSIENYLIKDSEGFKCKKLDQLRNEQDKKEDPIDENSQNCSQRKNIKDCLSTCERLKNKEVLQRTIPLRHSSVWQKHNFHSLDGTSTRAFHPRTGLPLLSSPVPQRKAQSGCFDLDSSFLHLKSLSSRSPQPCLNIEDDPDIHEKPLLSSSAPPVTSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGVFCPTHLTLPVEVSFYSVSEDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEMKRSVNKENIRHTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1093, "header": "tr|F1MD00-1|G3MZ46_BOVIN Computationally mapped isoform of Atos homolog protein A OS=Bos taurus OX=9913 GN=ATOSA PE=3 SV=3 CANONICAL=G3MZ46-1" }, "locus": { "chromosome": "10", "start_pos": 57807459, "end_pos": 57762685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034795.7", "url": "https://www.ensembl.org/id/ENSBTAT00000034795.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034680.6", "url": "https://www.ensembl.org/id/ENSBTAP00000034680.6" } ] } }, { "isoform_ac": "G3MZ46-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ46/entry", "sequence": { "sequence": "MKPDREAAHFSLMIKGPSLVVINYTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPITTKHECSDKLAQCRQARRTRSEVALLWKNNLPIMVEVMLLPDCCYSDDGPTTEGIDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGATPRNILYRISAADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRIQEHELKTHQHRNSTEADHCSTDSSQRVCSKQTWTMAPESIILHAKNGTTPEYSAAVKNVKLYPGIGSKSDYGTSQGNILGFSNIGEKKSHETSVRTLKSFSVVDSSDSSHQSSWQSVGETNPLIGSLIQERQEVIARIAQHLIHCDPSTSHVSEHPLNMQESSSLNSKLFRVSQENESVRRCKETFSVSFGSPELTSSEDTSEGKIRVKPETPRNGTYISNGLHSRQSVGETNPLISSLLQERQDIIARIAQHLEHIDPMASHMPRQSFNMQDSSSVPSKVFRSSYEDKNLLKKNKDDTSVSISNTKFSLLDDISEGKNSISNKYFSSFNCNSKVKPSLQPQIRRNLYKDNPSEIQGTFQQTQNKATGLTTPSNISHCKENNFDLTIRLENTCSECQFKKQEINNEIDKEYSNCNSIDKQVCTNKYKDKIINENYNPESFINHQCDNSKKNDSKVKVTVLEMSGYLSKHENECSNKDPKRPKPCEQNTQLNSIENYLIKDSEGFKCKKLDQLRNEQDKKEDPIDENSQNCSQRKNIKDCLSTCERLKNKEVLQRTIPLRHSSVWQKHNFHSLDGTSTRAFHPRTGLPLLSSPVPQRKAQSGCFDLDSSFLHLKSLSSRSPQPCLNIEDDPDIHEKPLLSSSAPPVTSLSLLGNFEESVLNYRLDPLGIVDGFTAEVGASGVFCPTHLTLPVEVSFYSVSEDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEMKRSVNKENIRHTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC", "length": 1106, "header": "tr|G3MZ46-1|G3MZ46_BOVIN Isoform 1 of Atos homolog protein A OS=Bos taurus OX=9913 GN=ATOSA PE=3 SV=3 CANONICAL=G3MZ46-1" }, "locus": { "chromosome": "10", "start_pos": 57807459, "end_pos": 57723972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065691.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065691.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054838.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054838.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:522864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522864", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZ46", "url": "https://www.uniprot.org/uniprotkb/G3MZ46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" }, { "start_pos": 995, "end_pos": 997, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZ46-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1106, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZ46-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZ46" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ46" }, { "id": "SM01177", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Atos-like conserved", "eco_id": "ECO_0000259", "start_pos": 908, "end_pos": 966, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 124 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 787, "end_pos": 789 }, { "start_pos": 995, "end_pos": 997 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"mass": { "chemical_mass": 64438.0, "monoisotopic_mass": 64438.0 }, "refseq": {}, "gene_names": [ { "name": "KRT2", "type": "recommended", "evidence": [ { "id": "G3MZ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ] } ], "protein_names": [ { "name": "Keratin 2", "type": "synonym", "evidence": [ { "id": "G3MZ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ71/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KRT2", "url": "https://www.uniprot.org/uniprotkb/G3MZ71", "locus": { "chromosome": "5", "start_pos": 27265075, "end_pos": 27256385, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039261", "url": "https://www.ensembl.org/id/ENSBTAG00000039261" } ] } } ], "crossref": [ { "id": "G3MZ71", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039261", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039261", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000054953", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054953", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCQITCK", "url": "https://omabrowser.org/oma/group/SCQITCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZ71", "url": "https://www.orthodb.org/?gene=G3MZ71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RVQ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B991", "url": "https://www.uniprot.org/uniprotkb/E1B991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B991-1", "url": "https://www.uniprot.org/uniprotkb/E1B991-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ71-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCQISYQSRGRGGGGGGFRGFSSGSAVVPGRSRLSGTSFSCLSRHGGGGGGFGGGGFGGGGFSSRSLVNLGGSRSTSISVAGGGGSFGSYGGFGGRGGGFGGGLGVGGGSFGGGRFGGGGGFGGLGGPGGFGGPGGFGPGGFPGGGIHEVSINQSLLQPLNVKVDPEIQNVKSQEREQIKALNNKFATFIDKVRFLEQQNQVLQTKWELLQQINVGTRTTNLEPLFQGYISQLQSHLDKLYSERMLQESELNNMQDLVEDFKKKYEDEVNKRTAAENEFVTLKKDVDHAYTNKVELQAKVDLLRQDVEFTKMLFDAVSRLLLNGPFVTDTTVILSMDNNRSLDLDSIITEVRAQYEEIAQRSKAEAEAVYHSKYEELRITAGKHGDSLKEVKMEISELNRMIQRLQGEIAQVKKQCKNVQDSIADAEQRGENALKDAQSKLNDLEEALQKAREDLARLLRDYQDLMNTKLSLDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSSISSGVASRAGFGGYGSGGRGSSYGGGFSSGSRSYSSGGRRSGSRSGGGGSYGSGGGSRGGSSSGGGYSSGGKHSSGGGARGGSSSGGGGYGSERGGSGSCEGGSSSVTFSFR", "length": 619, "header": "tr|G3MZ71-1|G3MZ71_BOVIN Isoform 1 of Keratin 2 OS=Bos taurus OX=9913 GN=KRT2 PE=1 SV=2 CANONICAL=G3MZ71-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RVQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVQ2/entry", "sequence": { "sequence": "MSCQISYQSRGRGGGGGGFRGFSSGSAVVPGRSRLSGTSFSCLSRHGGGGGGFGGGGFGGGGFSSRSLVNLGGSRSTSISVAGGGGFGGGLGVGGGSFGGGRFGGGGGFGGLGGPGGFGGPGGFGPGGFPGGGIHEVSINQSLLQPLNVKVDPEIQNVKSQEREQIKALNNKFATFIDKVRFLEQQNQVLQTKWELLQQINVGTRTTNLEPLFQGYISQLQSHLDKLYSERMLQESELNNMQDLVEDFKKKYEDEVNKRTAAENEFVTLKKDVDHAYTNKVELQAKVDLLRQDVEFTKMLFDAELSQMQQSVTDTTVILSMDNNRSLDLDSIITEVRAQYEEIAQRSKAEAEAVYHSKYEELRITAGKHGDSLKEVKMEISELNRMIQRLQGEIAQVKKQCKNVQDSIADAEQRGENALKDAQSKLNDLEEALQKAREDLARLLRDYQDLMNTKLSLDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSSISSGVASRAGFGGYGSGGRGSSYGGGFSSGSRSYSSGGRRSGSRSGGGGSYGSGGGSRGGSSSGGGYSSGGKHSSGGGARGGSSSGGGGYGSERGGSGSCEGGSSSVTFSFR", "length": 603, "header": "tr|A0AAA9RVQ2-1|G3MZ71_BOVIN Computationally mapped isoform of Keratin 2 OS=Bos taurus OX=9913 GN=KRT2 PE=1 SV=1 CANONICAL=G3MZ71-1" }, "locus": { "chromosome": "5", "start_pos": 27264071, "end_pos": 27256551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114793.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114793.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077452.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077452.1" } ] } }, { "isoform_ac": "E1B991-1", "url": "https://www.uniprot.org/uniprotkb/E1B991/entry", "sequence": { "sequence": "MTQRSSITIKSGGSRNFSASSANLLPGCRPSFSSISMIQSGKSFGGGFGGGFGTRSLHSFGGNKRISISSGYRSNRTGFGGAGYGLGLGGIGYRVGGVGSGCGFGGGMMSGAGGIHEVTVNQSLLTPLHLEIDPSLQRVRKEEKEQIKTLNNKFASFIDKVRFLEQQNKVLETKWSLLQEHKATRANLEPMFEGYINNLRRQLDSLGGERSRLEVELKSMQDVVEDFKNKYEEEINRRTAAENEFVVLKKDVDAAYMNKVELEAKVEALMDEINFLRSFYEAELAQLHAQISETSVVLSMDNNRKLDLDSIISEVKAQYEDIANRSRAEAESWYQIKYEELQRSAGQHGEDLRSTRMEISELNRVIQRLRSEIENVKKQCATLQAAIADAEQRGELALKDAKHKLAELEDALQKAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEECRLTGEGVGPVNISVVSSSGGSGYSGGGGLCMTGGGYGFGSSGFSSSGGSFSSTSGRGMSGTSSSMRIISKTSSSKSYRS", "length": 531, "header": "tr|E1B991-1|E1B991_BOVIN Computationally mapped isoform of IF rod domain-containing protein OS=Bos taurus OX=9913 GN=KRT2 PE=3 SV=4 CANONICAL=G3MZ71-1" }, "locus": { "chromosome": "5", "start_pos": 27480778, "end_pos": 27468173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038440.6", "url": "https://www.ensembl.org/id/ENSBTAT00000038440.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038253.6", "url": "https://www.ensembl.org/id/ENSBTAP00000038253.6" } ] } }, { "isoform_ac": "G3MZ71-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ71/entry", "sequence": { "sequence": "MSCQISYQSRGRGGGGGGFRGFSSGSAVVPGRSRLSGTSFSCLSRHGGGGGGFGGGGFGGGGFSSRSLVNLGGSRSTSISVAGGGGSFGSYGGFGGRGGGFGGGLGVGGGSFGGGRFGGGGGFGGLGGPGGFGGPGGFGPGGFPGGGIHEVSINQSLLQPLNVKVDPEIQNVKSQEREQIKALNNKFATFIDKVRFLEQQNQVLQTKWELLQQINVGTRTTNLEPLFQGYISQLQSHLDKLYSERMLQESELNNMQDLVEDFKKKYEDEVNKRTAAENEFVTLKKDVDHAYTNKVELQAKVDLLRQDVEFTKMLFDAVSRLLLNGPFVTDTTVILSMDNNRSLDLDSIITEVRAQYEEIAQRSKAEAEAVYHSKYEELRITAGKHGDSLKEVKMEISELNRMIQRLQGEIAQVKKQCKNVQDSIADAEQRGENALKDAQSKLNDLEEALQKAREDLARLLRDYQDLMNTKLSLDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSSISSGVASRAGFGGYGSGGRGSSYGGGFSSGSRSYSSGGRRSGSRSGGGGSYGSGGGSRGGSSSGGGYSSGGKHSSGGGARGGSSSGGGGYGSERGGSGSCEGGSSSVTFSFR", "length": 619, "header": "tr|G3MZ71-1|G3MZ71_BOVIN Isoform 1 of Keratin 2 OS=Bos taurus OX=9913 GN=KRT2 PE=1 SV=2 CANONICAL=G3MZ71-1" }, "locus": { "chromosome": "5", "start_pos": 27264071, "end_pos": 27256551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063931.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063931.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054865.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054865.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BHY5-1", "protein_name": "Keratin 2", "gene_name": "KRT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQLSCKSRGGGGGGGGRFRGFSSGSAVVSGGSRGSTTSFSCLSRHGGGGRGFGGGGFGSRSLVGLGGTKSISISVAGGGGSFGSGGGFGSRGSGFGGGSGFGGGSGFGGGSGFGGGGFGGGGFGGGRFGGGGALGGFGNLGGLGGFGPGGYPGGGIHEVSVNQSLLQPLNLKIDPEIQNVKSQEREQIKTLNNKFACFIDKVRFLEQQNQVLKTKWELLQQIDVRTCTINLEPLFQEYISRLQNQVNMLCAEKTSQDTELNNQQDLVEEFRKKYEDEINKRTAAENDFVTLKKDVDNAYINKADLQAKVDVLSQELAFLKILFDAELSQMQQNVTETNVILSMDNSRNLDLNDIISEVQSQYEEIAHRSKAEAEALYHSKYEELQITAGKHGDSLKEVKMEICELNRMIQRLQAEISQVRKQCKNVQDSIADAEQRGENALKDAQNKLKELEEALQKAKENLACLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASRAGFGGHGSGGKWSSSGGGYSSGSSSYSSGGRGSSSRGGGGGSYGSGGSFKGGSGSGGGYSSGGGYSSGGGSRGGAGFGGGGGSKSGSGSGGGGSCSERGASGSGEGCGSSVTFSFR", "length": 639 }, "evidence": [ { "id": "G3MZ71", "url": "https://omabrowser.org/oma/group/G3MZ71/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M5K3-1", "protein_name": "Keratin, type II cytoskeletal 2 epidermal", "gene_name": "Krt2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSCQISCKSRRGGGGGGGGFRGFSSGSAVVSGGSRRSTSGFSCLSRHGGGRGGSGGGGFGSQSLVGLGGYKSISTSVAGCGGGFGGRGGSGFGGGSSFGGGGGFGGGSGFGGGRGFGGSGGFGGGSGFGGGSGFGGGSGFGGGGFGGGGFGGGRFGGGSGFGGFGGPGGFPGGGIHEVSINQSLLQPLDVKVDPEIQNVKSQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQLDVGTRTTNLDPVFQAYISILKKQVDRLTAERTSQDSELNNMQDLVEDFKKKYEDEINKRTSAENEFVTIKKDVDSCYMDKTELQAKADILMQEVDFLRTLYDMELSQLQQTVTDTNVILSMDNNRNLDLDSIIAEVQSQYEIIAHKSKTESEELYHSKYEELQITAVKHGDSLKEIKMEISELNRTIQRLQGEISHVKKQCKGVQDSIADAEQRGEHALKDARTKLTDLEEAMQQARENLTRLLRDYQELMNTKLALDVEIATYRKLLEGEECRMTGEFSDNVSVSVTSSTISSSVASKAGFGSGGQSSGGRGSYGGGGSTYGSGGRNSGSRGGSGGGGFSSGGGSRGGSGSGGGGYSSGGGSRGGSGGGGYSSGGGSRGGSGTGGGYSSGGGSRGGSGGGAGGGSRGGSGSGGGGYSSGGGSRGGSGSGGGGYSSGGGSRGGSSSGGAVSGSERGGSGSGEGCGSGVTFSFR", "length": 714 }, "evidence": [ { "id": "G3MZ71", "url": "https://omabrowser.org/oma/group/G3MZ71/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P35908-1", "protein_name": "Keratin, type II cytoskeletal 2 epidermal", "gene_name": "KRT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFSFR", "length": 639 }, "evidence": [ { "id": "G3MZ71", "url": "https://omabrowser.org/oma/group/G3MZ71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TTY5-1", "protein_name": "Keratin, type II cytoskeletal 2 epidermal", "gene_name": "Krt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCQISCRSRRGGGGGGGGGFRGFSSGSAVVSGGSRRSNTSFSCISRHGGGRGGSGGGGFGSQSLVGLGGYKSISSSVAGNSGGYGGSSFGGSSGFGGGRGFGGGQGFGGSGGFGGGSGFGGGQGFGGGSRFGGGSGFGGGGFGGGSFGGGRFGGGPGGFGGPGGFPGGGIHEVSVNQSLLQPLDVKVDPEIQNVKSQEREQIKTLNNKFASFIDKVRFLEQQNQVLRTKWELLQQLDVGSRTTNLDPIFQAYIGMLKKQVDRLSAERTSQESELNNMQDLVEDFKKKYEDEINKRTSAENDFVTIKKDVDSCYMDKTELQARLDILAQEVNFLRTLYDAELSQLQQDVTDTNVILSMDNNRNLDLDSIIAEVQNQYEMIAHKSKAESEELYHSKYEELQVTAVKHGDSLKEIKMEISELNRTIQRLQGEISHVKKQCKGVQDSIADAEQRGEHAIKDARGKLTDLEEALQQCREDLARLLRDYQELMNTKLSLDVEIATYRKLLEGEECRMSGDFSDNVSVSITSSTISSSVASKTGFGSGGQSSGGRGSYGGRGGGGGGGSTYGSGGRSSGSRGSGSGSGGGGYSSGGGSRGGSGGGYGSGGGSRGGSGGGYGSGGGSGSGGGYSSGGGSRGGSGGGGVSSGGGSRGGSSSGGGSRGGSSSGGGGYSSGGGSRGGSSSGGAGSSSEKGGSGSGEGCGSGVTFSFR", "length": 707 }, "evidence": [ { "id": "G3MZ71", "url": "https://omabrowser.org/oma/group/G3MZ71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6IG02-1", "protein_name": "Keratin, type II cytoskeletal 2 epidermal", "gene_name": "Krt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCQISCKSRRGGGGGGGGGFRGFSSGSAVVSGGSRRSTSGFSCLSRHGGGRGGSGGGGFGSQSLVGLGGYKSISSSVAGYGGGFGGRSYGGFGGGSGFGGSGGFGGGSGFGGGRGFGGGSGFGGGSGFGGGSGFGGGSGFGGGGFGGGRFGGGPGGFGGPGGFPGGGIHEVSVNQSLLQPLDVKVDPEIQNVKSQEREQIKTLNNKFASFIDTVRFLEQQNQVLHTKWELLQQLDVGTRTTNLDPVFQAYIGILKKQVDRLTAERNSQDSELNNMQDLVEDFKKKYEDEINKRTSAENDFVTIKKDVDSCYMDKTELQAKMEMLTQEVDFLRTLYDTELSQLQQNVTDTNVILSMDNNRNLDLDSIIAEVQSQYEIIAHKSKAESEELYHSKANEELQVTAVKHGDSLKEIKMEISELNRTIQRLQGEISHVKKQCKGVQDSIADAEQRGEHAIKDARGKLTDLEEALQQGRENLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDFSDNVSVSVTSSTISSSVASKAGFGSGGQSSGGRGSYGGRGGGSTYGSGGRSSGVRGSGSGSGGGGYSSGGGSRGGSGGGGYSTGGGSRGGSSSGGGGYSSGGGSRGDSSSGGGSRGGSGGGSRGGSGGGGYSSGGGSRGGSSSGGAVSGSERGGSGSGEGCGSGVTFSFR", "length": 685 }, "evidence": [ { "id": "G3MZ71", "url": "https://omabrowser.org/oma/group/G3MZ71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "keratinocyte activation", "id": "GO:0032980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032980", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "keratinocyte migration", "id": "GO:0051546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051546", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "positive regulation of epidermis development", "id": "GO:0045684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045684", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "cornification", "id": "GO:0070268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070268", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "keratinocyte proliferation", "id": "GO:0043616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043616", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "G3MZ71", "url": "https://www.uniprot.org/uniprotkb/G3MZ71" } ], "pmid": "" }, { "name": "structural constituent of skin 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X746-1", "uniprot_ac": "G3X746", "uniprot_id": "G3X746_BOVIN", "mass": { "chemical_mass": 235285.0, "monoisotopic_mass": 235285.0 }, "refseq": {}, "gene_names": [ { "name": "CABIN1", "type": "recommended", "evidence": [ { "id": "G3X746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X746" } ] } ], "protein_names": [ { "name": "Calcineurin-binding protein cabin-1", "type": "recommended", "evidence": [ { "id": "G3X746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X746/entry#names_and_taxonomy" } ] }, { "name": "Calcineurin inhibitor", "type": "synonym", "evidence": [ { "id": "G3X746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X746/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X746", "url": "https://www.uniprot.org/uniprotkb/G3X746" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CABIN1", "url": "https://www.uniprot.org/uniprotkb/G3X746", "locus": { "chromosome": "17", "start_pos": 71417146, "end_pos": 71345464, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024708", "url": "https://www.ensembl.org/id/ENSBTAG00000024708" } ] } } ], "crossref": [ { "id": "ENSBTAG00000024708", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024708", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13839", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13839", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3X746", "url": "https://www.orthodb.org/?gene=G3X746", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15502:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15502:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2559584", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RXQ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE10", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE10-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X746", "url": "https://www.uniprot.org/uniprotkb/G3X746", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X746-1", "url": "https://www.uniprot.org/uniprotkb/G3X746-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVPSGDEKEGLKHPGLMLKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRVPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFQEQPCLRQDSLRMFLQCDMSIHEVSVSAAEAQAIVDEALGLRRRRQALTVREKEPDLKLLQPIPFLTWKCLGESLLATYHHLTTCEPPRPSLGKRIDLSDYQDPGQRPVSPEEVAPVSVLQPSPASASPAASVAEPVLTFTPVPTASFPLHSPSLLETGVPTGDVSGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLLKFLPSRLRKLDPEEEDDPFNSYEVPPEAKLESFPSTGPHRLSSDLATFVESEEQDVQAFLLGNLSNGGILELMMRFLKSMGHRFLLRWPPGLAEVVLSTYHSWRRHSASLPNPLLRDCSNRHIQEMMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGVLNGRFGPDFPGAHFLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSAAAQAAAGAEQRDVVIRLPNLHNDSVVSLEEIDKNLRSLERCQSLEEAQRLYEAGDHRAVVRLLRPTLRPSGCDRAKHLEFMTSVPERPAQLLLLQDSLLRLEDHRQCFECSDVALNEAVQQMVNATETAAKEQWVATVTQLLQGMEQALSADGSTLRDLSAAGGLTRLTNNLIQVIDCSMAVQEEPKEPHVTSVLPWVILYRVIRQEEDAFRSLCHQQQLQSPADEASAEPPMLPSSLMLLNTAHEYLGRRAWCCNSDGALLRFYVRVLQKELAAPTPEDAHPYKEELETALEQCFYCLYSHPSKKSKARYLEEHSAPQVDLLWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLRRIASIVPRTARPALSLDRVSAYIEGTSVEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAVKFYMHDICVCPDRFDSWAGMALARASRIQDKLNSNELKSDGPVWKHATPVLSCFRRALEIDSSNLSLWIEFGTMSYALHSFASRQLKQWRPELPAELVQQLEERRDSMLETARHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPPVYLRHYGQASHLLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVSAEVLVGFMKEAAEGPFARGEEKNAPKASEKEKACLVDEDSHSSAGTLPGPGAPLPSSGPGLTSPPYTATPVDHDYVKCKKPHQQATPDERSQDSTAVALSDSSSTQDFFSEPASSQEGSRRPCAEKRPPAPISQAGLPGKDLPATTEEKGKAEESSESNEGSRATEQGSQKPAADAPGPAGGPAKPQMPGPAPGDGRKRADTPGELLAFPQGLPTGAEEQRQFLTEQCVASLHLCLGRFPQHYKSLYRLAFLYTHSRTHRNLQWARDVLLGSGIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSVVLLLKVLAQLRDHGTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELTEGSERLGPKACGFPGARMTTDVSHRASPEDDKEGLPHPKKPPLGDGSGPGAEPGGKVGPLNHRPMAMDAGEGADQAGERKDKESPRAGPAEPMDTCDATARGADPERGPPPLQPGCPPRDRGPESRPTELSLEELSISARPPGPPALAPPTATPTPGPRPGTHPEEAPLRPSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVACDLGRIERIMSETYMLIKQVDEEAALEQAVKFCQAHLGAAAQRQAAGDMPTTPKHPKDARENVFPAATAPVAPEPTPADAPPRPSDGHAKPRLVSATASTPDPAKDPGPPRLQRPEAAPSTSSLRPGAEEPAGGAEGPGFPPQEPQDSEHVKTAPEGPAAEAAPRTGAQPACSQVASSKAPGGGSAPPPEGPLSKAEPGRAKSRLLPNMPKLVIPSSTTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAATVRKESLCQPALEVLETSSQESSLESETDEDEDYMDI", "length": 2134, "header": "tr|G3X746-1|G3X746_BOVIN Isoform 1 of Calcineurin-binding protein cabin-1 OS=Bos taurus OX=9913 GN=CABIN1 PE=4 SV=3 CANONICAL=G3X746-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RXQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXQ1/entry", "sequence": { "sequence": "MIRIAALNASSTVEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVPSGDEKEGLKHPGLMLKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRVPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFQEQPCLRQDSLRMFLQCDMSIHEVSVSAAEAQAIVDEALGLRRRRQALTVREKEPDLKLLQPIPFLTWKCLGESLLATYHHLTTCEPPRPSLGKRIDLSDYQDPGQRPVSPEEVAPVSVLQPSPASASPAASVAEPVLTFTPVPTASFPLHSPSLLETGVPTGDVSGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLLKFLPSRLRKLDPEEEDDPFNSYEVPPEAKLESFPSTGPHRLSSDLATFVESEEQDVQAFLLGNLSNGGILELMMRFLKSMGHRFLLRWPPGLAEVVLSTYHSWRRHSASLPNPLLRDCSNRHIQEMMLMSLSCMELQLDQWLLTKGRSSAGVLNGRFGPDFPGAHFLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSAAAQAAAGAEQRDVVIRLPNLHNDSVVSLEEIDKNLRSLERCQSLEEAQRLYEAGDHRAVVRLLRPTLRPSGCDRAKHLEFMTSVPERPAQLLLLQDSLLRLEDHRQCFECSDVALNEAVQQMVNATETAAKEQWVATVTQLLQGMEQALSADGSTLRDLSAAGGLTRLTNNLIQVIDCSMAVQEEPKEPHVTSVLPWVILYRVIRQEEDAFRSLCHQQQLQSPADEASAEPPMLPSSLMLLNTAHEYLGRRAWCCNSDGALLRFYVRVLQKELAAPTPEDAHPYKEELETALEQCFYCLYSHPSKKSKARYLEEHSAPQVDLLWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLRRIASIVPRTARPALSLDRVSAYIEGTSVEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAVKFYMHDICVCPDRFDSWAGMALARASRIQDKLNSNELKSDGPVWKHATPVLSCFRRALEIDSSNLSLWIEFGTMSYALHSFASRQLKQWRPELPAELVQQVYFRLHASILKLLGKPDSGVSAEVLVGFMKEAAEGPFARGEEKNAPKASEKEKACLVDEDSHSSAGTLPGPGAPLPSSGPGLTSPPYTATPVDHDYVKCKKPHQQATPDERSQDSTAVALSDSSSTQDFFSEPASSQEGSRRPCAEKRPPAPISQAGLPGKDLPATTEEKGKAEESSESNEGSRATEQGSQKPAADAPGPAGGPAKPQMPGPAPGDGRKRADTPGELLAFPQGLPTGAEEQRQFLTEQCVASLHLCLGRFPQHYKSLYRLAFLYTHSRTHRNLQWARDVLLGSGIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSVVLLLKVLAQLRDHGTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELTEGSERLGPKACGFPGARMTTDVSHRASPEDDKEGLPHPKKPPLGDGSGPGAEPGGKVGPLNHRPMAMDAGEGADQAGERKDKESPRAGPAEPMDTCDATARGADPERGPPPLQPGCPPRDRGPESRPTELSLEELSISARPPGPPALAPPTATPTPGPRPGTHPEEAPLRPSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVACDLGRIERIMSETYMLIKQVDEEAALEQAVKFCQAHLGAAAQRQAAGDMPTTPKHPKDARENVFPAATAPVAPEPTPADAPPRPSDGHAKPRLVSATASTPDPAKDPGPPRLQRPEAAPSTSSLRPGAEEPAGGAEGPGFPPQEPQDSEHVKTAPEGPAAEAAPRTGAQPACSQVASSKAPGGGSAPPPEGPLSKAEPGRAKSRLLPNMPKLVIPSSTTKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAATVRKESLCQPALEVLETSSQESSLESETDEDEDYMDI", "length": 2070, "header": "tr|A0AAA9RXQ1-1|G3X746_BOVIN Computationally mapped isoform of Calcineurin-binding protein cabin-1 OS=Bos taurus OX=9913 GN=CABIN1 PE=4 SV=1 CANONICAL=G3X746-1" }, "locus": { "chromosome": "17", "start_pos": 71416931, "end_pos": 71350651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106236.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106236.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074602.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074602.1" } ] } }, { "isoform_ac": "A0AAA9TE10-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE10/entry", "sequence": { "sequence": "MGAHLVVRRAAGRRRGSGRPGGCCGDAWSPWAALPRRHRRVAPEALTMIRIAALNASSTVEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVPSGDEKEGLKHPGLMLKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRVPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFQEQPCLRQDSLRMFLQCDMSIHEVSVSAAEAQAIVDEALGLRRRRQALTVREKEPDLKLLQPIPFLTWKCLGESLLATYHHLTTCEPPRPSLGKRIDLSDYQDPGQRPVSPEEVAPVSVLQPSPASASPAASVAEPVLTFTPVPTASFPLHSPSLLETGVPTGDVSGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLLKFLPSRLRKLDPEEEDDPFNSYEVPPEAKLESFPSTGPHRLSSDLATFVESEEQDVQAFLLGNLSNGGILELMMRFLKSMGHRFLLRWPPGLAEVVLSTYHSWRRHSASLPNPLLRDCSNRHIQEMMLMSLSCMELQLDQWLLTKGRSSAGVLNGRFGPDFPGAHFLGDLLQLSFASSQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSAAAQAAAGAEQRDVVIRLPNLHNDSVVSLEEIDKNLRSLERCQSLEEAQRLYEAGDHRAVVRLLRPTLRPSGCDRAKHLEFMTSVPERPAQLLLLQDSLLRLEDHRQCFECSDVALNEAVQQMVNATETAAKEQWVATVTQLLQGMEQALSADGSTLRDLSAAGGLTRLTNNLIQVIDCSMAVQEEPKEPHVTSVLPWVILYRVIRQEEDAFRSLCHQQQLQSPADEASAEPPMLPSSLMLLNTAHEYLGRRAWCCNSDGALLRFYVRVLQKELAAPTPEDAHPYKEELETALEQCFYCLYSHPSKKSKARYLEEHSAPQVDLLWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLRRIASIVPRTARPALSLDRVSAYIEGTSVEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAVKFYMHDICVCPDRFDSWAGMALARASRIQDKLNSNELKSDGPVWKHATPVLSCFRRALEIDSSNLSLWIEFGTMSYALHSFASRQLKQWRPELPAELVQQLEERRDSMLETARHCFTSAARCEGDGDEEEWLIHYMLGKVAEKQQQPPPVYLRHYGQASHLLHEEAARYPKKIHYHNPPELAMEALEVYFRLHASILKLLGKPDSGVSAEVLVGFMKEAAEGPFARGEEKNAPKASEKEKACLVDEDSHSSAGTLPGPGAPLPSSGPGLTSPPYTATPVDHDYVKCKKPHQQATPDERSQDSTAVALSDSSSTQDFFSEPASSQEGSRRPCAEKRPPAPISQAGLPGKDLPATTEEKGKAEESSESNEGSRATEQGSQKPAADAPGPAGGPAKPQMPGPAPGDGRKRADTPGELLAFPQGLPTGAEEQRQFLTEQCVASLHLCLGRFPQHYKSLYRLAFLYTHSRTHRNLQWARDVLLGSGIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSVVLLLKVLAQLRDHGTLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELTEGSERLGPKACGFPGARMTTDVSHRASPEDDKEGLPHPKKPPLGDGSGPGAEPGGKVGPLNHRPMAMDAGEGADQAGERKDKESPRAGPAEPMDTCDATARGADPERGPPPLQPGCPPRDRGPESRPTELSLEELSISARPPGPPALAPPTATPTPGPRPGTHPEEAPLRPSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVACDLGRIERIMSETYMLIKQVDEEAALEQAVKFCQAHLGAAAQRQAAGDMPTTPKHPKDARENVFPAATAPVAPEPTPADAPPRPSDGHAKPRLVSATASTPDPAKDPGPPRLQRPEAAPSTSSLRPGESVPSTQRAGRAEPRRAQSPSRPVAAEMWAPPVR", "length": 2068, "header": "tr|A0AAA9TE10-1|G3X746_BOVIN Computationally mapped isoform of Calcineurin-binding protein cabin-1 OS=Bos taurus OX=9913 GN=CABIN1 PE=4 SV=1 CANONICAL=G3X746-1" }, "locus": { "chromosome": "17", "start_pos": 71414500, "end_pos": 71345562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127863.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127863.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095008.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095008.1" } ] } }, { "isoform_ac": "G3X746-1", "url": "https://www.uniprot.org/uniprotkb/G3X746/entry", "sequence": { "sequence": 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"length": 2134, "header": "tr|G3X746-1|G3X746_BOVIN Isoform 1 of Calcineurin-binding protein cabin-1 OS=Bos taurus OX=9913 GN=CABIN1 PE=4 SV=3 CANONICAL=G3X746-1" }, "locus": { "chromosome": "17", "start_pos": 71416931, "end_pos": 71350651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018360.6", "url": "https://www.ensembl.org/id/ENSBTAT00000018360.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018360.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018360.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1787, "start_aa": "Thr", "end_pos": 1787, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1787", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1789, "start_aa": "Thr", "end_pos": 1789, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1789", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1913, "start_aa": "Thr", "end_pos": 1913, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1913", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 895, "start_aa": "Thr", "end_pos": 895, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr895", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-2559584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559584", "resource": "Reactome", "description": "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X746", "url": "https://www.uniprot.org/uniprotkb/G3X746" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X746", "url": "https://www.uniprot.org/uniprotkb/G3X746" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "G3X746", "url": 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"n_glycosylation_sequon" }, { "start_pos": 1542, "end_pos": 1544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1569, "end_pos": 1571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X746" }, { "id": "PF09047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcineurin-binding protein cabin-1 MEF2-binding", "eco_id": "ECO_0000259", "start_pos": 2070, "end_pos": 2104, 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"https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CRWNGAL", "url": "https://omabrowser.org/oma/group/CRWNGAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RJL7", "url": "https://www.orthodb.org/?gene=F6RJL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10131:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10131:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21355", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21355", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RY29", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RY29-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJL7-1", "url": "https://www.uniprot.org/uniprotkb/F6RJL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCSTLHASPPKQVGRRGSWLDQTSFPDDWEVAPIKKKKKKTAACLECGLFRGGGGHPRAGLGLIWAAEPRSREECGRSLRLGPRFLWRGAQPGLPAQLDSPDLVAMLQLPSTWRLEPRAPGRHVAPETELLTPEKRIFVAWPGQSPEALRPIQRPSSFRPPQPWREAGPRFFFPRGRGNPCSSAVASLAERRPRSRRPAGWVGSAAERALGPRGRSPAPSSGGRAQGPRAGPGRQSAPPGAGSAAGARHGLWGLRAPGPARPCPPAMPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLSIRCIHSEEGCRWNGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAFESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPGHLKDSCSTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS", "length": 737, "header": "tr|F6RJL7-1|F6RJL7_BOVIN Isoform 1 of TNF receptor-associated factor 4 OS=Bos taurus OX=9913 GN=TRAF4 PE=3 SV=2 CANONICAL=F6RJL7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RY29-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY29/entry", "sequence": { "sequence": "MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLSIRCIHSEEGCRWNGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAFESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS", "length": 195, "header": "tr|A0AAA9RY29-1|F6RJL7_BOVIN Computationally mapped isoform of TNF receptor-associated factor 4 OS=Bos taurus OX=9913 GN=TRAF4 PE=3 SV=1 CANONICAL=F6RJL7-1" }, "locus": { "chromosome": "19", "start_pos": 20170561, "end_pos": 20165077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100975.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100975.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074718.1" } ] } }, { "isoform_ac": "F6RJL7-1", "url": "https://www.uniprot.org/uniprotkb/F6RJL7/entry", "sequence": { "sequence": "MGCSTLHASPPKQVGRRGSWLDQTSFPDDWEVAPIKKKKKKTAACLECGLFRGGGGHPRAGLGLIWAAEPRSREECGRSLRLGPRFLWRGAQPGLPAQLDSPDLVAMLQLPSTWRLEPRAPGRHVAPETELLTPEKRIFVAWPGQSPEALRPIQRPSSFRPPQPWREAGPRFFFPRGRGNPCSSAVASLAERRPRSRRPAGWVGSAAERALGPRGRSPAPSSGGRAQGPRAGPGRQSAPPGAGSAAGARHGLWGLRAPGPARPCPPAMPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLSIRCIHSEEGCRWNGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAFESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPGHLKDSCSTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS", "length": 737, "header": "tr|F6RJL7-1|F6RJL7_BOVIN Isoform 1 of TNF receptor-associated factor 4 OS=Bos taurus OX=9913 GN=TRAF4 PE=3 SV=2 CANONICAL=F6RJL7-1" }, "locus": { "chromosome": "19", "start_pos": 20170561, "end_pos": 20164276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056164.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056164.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050075.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050075.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A7J8-1", "protein_name": "TNF receptor-associated factor", "gene_name": "TRAF4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPTKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAFESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPGHLKDSCSTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSEPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS", "length": 470 }, "evidence": [ { "id": "F6RJL7", "url": "https://omabrowser.org/oma/group/F6RJL7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B1WC90-1", "protein_name": "TNF receptor-associated factor", "gene_name": "Traf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS", "length": 470 }, "evidence": [ { "id": "F6RJL7", "url": "https://omabrowser.org/oma/group/F6RJL7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61382-1", "protein_name": "TNF receptor-associated factor 4", "gene_name": "Traf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHVEESVKPHLAMMCALVSRQRQELQELRRELEELSIGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKILS", "length": 470 }, "evidence": [ { "id": "F6RJL7", "url": "https://omabrowser.org/oma/group/F6RJL7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BUZ4-1", "protein_name": "TNF receptor-associated factor 4", "gene_name": "TRAF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKILS", "length": 470 }, "evidence": [ { "id": "F6RJL7", "url": "https://omabrowser.org/oma/group/F6RJL7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "F6RJL7", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RJL7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 737, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RJL7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RJL7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" }, { "id": "PS50144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MATH", "eco_id": "ECO_0000259", "start_pos": 574, "end_pos": 729, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 285, "end_pos": 325, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJL7" }, { "id": "PS50145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRAF-type", "eco_id": "ECO_0000259", "start_pos": 369, "end_pos": 421, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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"type": "recommended", "evidence": [ { "id": "F6RLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLW9/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.135", "type": "synonym", "evidence": [ { "id": "F6RLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLW9/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylcholine--retinol O-acyltransferase", "type": "synonym", "evidence": [ { "id": "F6RLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLW9/entry#names_and_taxonomy" } ] }, { "name": "lecithin retinol acyltransferase", "type": "synonym", "evidence": [ { "id": "NP_803469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803469" } ] }, { "name": "phosphatidylcholine--retinol O-acyltransferase", "type": "synonym", "evidence": [ { "id": "NP_803469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803469" } ] } ], "function": [ { "annotation": "LRAT is not required for isomerase activity beyond synthesis of retinyl-ester substrate, and the association of Rpe65 with membranes is neither dependent upon LRAT nor the result of S-palmitoylation", "evidence": [ { "database": "RefSeq", "id": "NP_803469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803469" }, { "database": "PubMed", "id": "17504753", "url": "https://glygen.org/publication/PubMed/17504753" } ] }, { "annotation": "These experiments are consistent with an expanded role for LRAT function as a protein palmitoyl transferase.", "evidence": [ { "database": "RefSeq", "id": "NP_803469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803469" }, { "database": "PubMed", "id": "16939223", "url": "https://glygen.org/publication/PubMed/16939223" } ] }, { "annotation": "Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology.", "evidence": [ { "database": "UniProtKB", "id": "A0AAF6DLQ8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLQ8#function" }, { "database": "UniProtKB", "id": "ARBA00058039", "url": "https://www.uniprot.org/uniprotkb/ARBA00058039#function" }, { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9#function" }, { "database": "UniProtKB", "id": "A0AAA9SUU6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUU6#function" }, { "database": "UniProtKB", "id": "A0AAA9RYU0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYU0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LRAT", "url": "https://www.uniprot.org/uniprotkb/F6RLW9", "locus": { "chromosome": "17", "start_pos": 2668568, "end_pos": 2676877, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017167", "url": "https://www.ensembl.org/id/ENSBTAG00000017167" } ] } } ], "crossref": [ { "id": "F6RLW9", "url": "https://alphafold.ebi.ac.uk/entry/F6RLW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017167", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "281285", "url": "https://www.ncbi.nlm.nih.gov/gene/281285", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281285", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281285", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6RLW9", "url": "https://www.orthodb.org/?gene=F6RLW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46678:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46678:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2453902", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2453902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_803469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803469", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17469", "url": "https://www.rhea-db.org/rhea/17469", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43904", "url": "https://www.rhea-db.org/rhea/43904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55320", "url": "https://www.rhea-db.org/rhea/55320", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56240", "url": "https://www.rhea-db.org/rhea/56240", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56244", "url": "https://www.rhea-db.org/rhea/56244", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56248", "url": "https://www.rhea-db.org/rhea/56248", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RYU0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUU6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLQ8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLW9-1", "url": "https://www.uniprot.org/uniprotkb/F6RLW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNPMLEAVSLVLEKLLFISYFKFFSSGAPGEDKAGNTLYEISSFLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKGLTQKVVSNKRLILGVIGRVASIRVDTVEDFAYGAEILVNHLDRSLKKKALLNEEVAQRAEKLLGITPYSLLWNNCEHFVTYCRFGTAISPQADKFCENVKIIIRDQRSVLASAVLGLASIFCLGLTSYTTLPAIFIPFFLWMAG", "length": 230, "header": "tr|F6RLW9-1|F6RLW9_BOVIN Isoform 1 of Lecithin retinol acyltransferase OS=Bos taurus OX=9913 GN=LRAT PE=3 SV=1 CANONICAL=F6RLW9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYU0/entry", "sequence": { "sequence": "MKNPMLEAVSLVLEKLLFISYFKFFSSGAPGEDKAGNTLYEISSFLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKGLTQKVVSNKRLILGVIGRVASIRVDTVEDFAYGAEILVNHLDRSLKKKALLNEEVAQRAEKLLGITPYSLLWNNCEHFVTYCRFGTAISPQADKVPRVTLTPVGSVGTLPPFPKLSSPLGAGIGF", "length": 211, "header": "tr|A0AAA9RYU0-1|F6RLW9_BOVIN Computationally mapped isoform of Lecithin retinol acyltransferase OS=Bos taurus OX=9913 GN=LRAT PE=3 SV=1 CANONICAL=F6RLW9-1" }, "locus": { "chromosome": "17", "start_pos": 2675094, "end_pos": 2674462, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089826.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089826.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076306.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076306.1" } ] } }, { "isoform_ac": "A0AAA9SUU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUU6/entry", "sequence": { "sequence": "MKNPMLEAVSLVLEKLLFISYFKFFSSGAPGEDKAGNTLYEISSFLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKGLTQKVVSNKRLILGVIGRVASIRVDTVEDFAYGAEILVNHLDRSLKKKALLNEEVAQRAEKLLGITPYSLLWNNCEHFVTYCRFGTAISPQADKGFVAQRCPYRLLNINPELEGISYHGATQRCLLDRTLEMR", "length": 219, "header": "tr|A0AAA9SUU6-1|F6RLW9_BOVIN Computationally mapped isoform of Lecithin retinol acyltransferase OS=Bos taurus OX=9913 GN=LRAT PE=3 SV=1 CANONICAL=F6RLW9-1" }, "locus": { "chromosome": "17", "start_pos": 2675094, "end_pos": 2672280, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108113.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108113.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087939.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087939.1" } ] } }, { "isoform_ac": "A0AAF6DLQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLQ8/entry", "sequence": { "sequence": "MKNPMLEAVSLVLEKLLFISYFKFFSSGAPGEDKAGNTLYEISSFLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKGLTQKVVSNKRLILGVIGRVASIRVDTVEDFAYGAEILVNHLDRSLKKKALLNEEVAQRAEKLLGITPYSLLWNNCEHFVTYCRISRNARRKSVAMQYRCQQRQRAAQLLLQKSSGCPPSVVEMTRASD", "length": 214, "header": "tr|A0AAF6DLQ8-1|F6RLW9_BOVIN Computationally mapped isoform of Lecithin retinol acyltransferase OS=Bos taurus OX=9913 GN=LRAT PE=3 SV=1 CANONICAL=F6RLW9-1" }, "locus": { "chromosome": "17", "start_pos": 2675094, "end_pos": 2674252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049569.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049569.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046443.5", "url": "https://www.ensembl.org/id/ENSBTAP00000046443.5" } ] } }, { "isoform_ac": "F6RLW9-1", "url": "https://www.uniprot.org/uniprotkb/F6RLW9/entry", "sequence": { "sequence": "MKNPMLEAVSLVLEKLLFISYFKFFSSGAPGEDKAGNTLYEISSFLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKGLTQKVVSNKRLILGVIGRVASIRVDTVEDFAYGAEILVNHLDRSLKKKALLNEEVAQRAEKLLGITPYSLLWNNCEHFVTYCRFGTAISPQADKFCENVKIIIRDQRSVLASAVLGLASIFCLGLTSYTTLPAIFIPFFLWMAG", "length": 230, "header": "tr|F6RLW9-1|F6RLW9_BOVIN Isoform 1 of Lecithin retinol acyltransferase OS=Bos taurus OX=9913 GN=LRAT PE=3 SV=1 CANONICAL=F6RLW9-1" }, "locus": { "chromosome": "17", "start_pos": 2675094, "end_pos": 2670172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022813.5", "url": "https://www.ensembl.org/id/ENSBTAT00000022813.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022813.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022813.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Palmitoyl transferase activity of lecithin retinol acyl transferase.", "journal": "Biochemistry", "date": "2006", "authors": "Xue L, Jahng WJ, Gollapalli D, Rando RR", "evidence": [ { "database": "RefSeq", "id": "NP_803469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803469" } ], "reference": [ { "type": "PubMed", "id": "16939223", "url": "https://glygen.org/publication/PubMed/16939223" } ] }, { "title": "Role of LRAT on the retinoid isomerase activity and membrane association of Rpe65.", "journal": "The Journal of biological chemistry", "date": "2007-07-20", "authors": "Jin Minghao, Yuan Quan, Li Songhua, Travis Gabriel H", "evidence": [ { "database": "RefSeq", "id": "NP_803469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803469" } ], "reference": [ { "type": "PubMed", "id": "17504753", "url": "https://glygen.org/publication/PubMed/17504753" } ] } ], "pathway": [ { "id": "bta:281285", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281285", "resource": "KEGG Pathway" }, { "id": "R-BTA-2453902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2453902", "resource": "Reactome", "description": "The canonical retinoid cycle in rods (twilight vision)" }, { "id": "R-BTA-975634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "resource": "Reactome", "description": "Retinoid metabolism and transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylcholine-retinol O-acyltransferase activity", "id": "GO:0047173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047173", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" }, { "name": "O-palmitoyltransferase activity", "id": "GO:0016416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016416", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" }, { "name": "vitamin A metabolic process", "id": "GO:0006776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006776", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "F6RLW9", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17469", "name": "", "equation": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9BGL2-1", "F6RLW9-1" ], "evidence": [ { "id": "17469", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17469" } ] }, { "id": "43904", "name": "", "equation": "all-trans-retinol + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9BGL2-1", "F6RLW9-1" ], "evidence": [ { "id": "43904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43904" } ] }, { "id": "55320", "name": "", "equation": "1,2-diheptanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = all-trans-retinyl heptanoate + 2-heptanoyl-sn-glycero-3-phosphocholine + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9BGL2-1", "F6RLW9-1" ], "evidence": [ { "id": "55320", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55320" } ] }, { "id": "56240", "name": "", "equation": "1,2-dioctanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-octanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl octanoate + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9BGL2-1", "F6RLW9-1" ], "evidence": [ { "id": "56240", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56240" } ] }, { "id": "56244", "name": "", "equation": "all-trans-retinol--[retinol-binding protein] + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + all-trans-retinyl hexadecanoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9BGL2-1", "F6RLW9-1" ], "evidence": [ { "id": "56244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56244" } ] }, { "id": "56248", "name": "", "equation": "1,2-didodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = 2-dodecanoyl-sn-glycero-3-phosphocholine + all-trans-retinyl dodecanoate + apo--[retinol-binding protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9BGL2-1", "F6RLW9-1" ], "evidence": [ { "id": "56248", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56248" } ] }, { "id": "R-BTA-2404137", "name": "LRAT esterifies RBP1:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, lipid droplet, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RLW9-1" ], "evidence": [ { "id": "R-BTA-2404137", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2404137" } ] }, { "id": "R-BTA-2453855", "name": "LRAT esterifies RBP1:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, lipid droplet, plasma membrane", "input_participant_list": [ "R-ALL-9982900" ], "output_participant_list": [], "enzyme_list": [ "F6RLW9-1" ], "evidence": [ { "id": "R-BTA-2453855", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2453855" } ] }, { "id": "R-BTA-975608", "name": "LRAT esterifies RBP2:atROL and FACYLs to atREs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-BTA-975603", "R-ALL-9982625", "R-ALL-9982479" ], "enzyme_list": [ "F6RLW9-1" ], "evidence": [ { "id": "R-BTA-975608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975608" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9982479", "participant_name": "2acPC [plasma membrane]", "crossref": [ { "id": "57875", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9982625", "participant_name": "atRE [cytosol]", "crossref": [ { "id": "63410", "database": "ChEBI", "url": "" }, { "id": "C02075", "database": "KEGG Gene", "url": "" }, { "id": "C02075", "database": "COMPOUND", "url": "" }, { "id": "All-trans-Retinyl-Esters", "database": "AraCyc", "url": "" } ] }, { "participant_id": "R-ALL-9982900", "participant_name": "RCOO- [plasma membrane]", "crossref": [ { "id": "28868", "database": "ChEBI", "url": "" }, { "id": "C02403", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-BTA-975603", "participant_name": "RBP2 [cytosol]", "crossref": [ { "id": "A7MBG1", "database": "UniProt", "url": "" }, { "id": "XP_010799862.1", "database": "RefSeq", "url": "" }, { "id": "XP_010799863.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAP00000056900", "database": "ENSEMBL", "url": "" }, { "id": "33813", "database": "VGNC", "url": "" }, { "id": "ENSBTAT00000078995", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAG00000015056", "database": "ENSEMBL", "url": "" }, { "id": "NP_001094729.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F6RLW9", "gene_name": "LRAT", "activity": [ { "ec_number": "2.3.1.135", "activity": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine.", "evidence": [ { "id": "F6RLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ] }, { "ec_number": "2.3.1.135", "activity": "", "evidence": [ { "id": "F6RLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" } ] } ] }, { "uniprot_ac": "Q9BGL2", "gene_name": "LRAT", "activity": [ { "ec_number": "2.3.1.135", "activity": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine.", "evidence": [ { "id": "Q9BGL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BGL2" } ] }, { "ec_number": "2.3.1.135", "activity": "", "evidence": [ { "id": "Q9BGL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BGL2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RLW9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 230, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RLW9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RLW9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLW9" }, { "id": "PS51934", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51934" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRAT", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 177, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.135", "ec_name": "all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine = apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine.", "evidence": [ { "id": "2.3.1.135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.135" }, { "id": "2.3.1.135", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.135" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": 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"table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYQ6-1", "uniprot_ac": "G3MYQ6", "uniprot_id": "G3MYQ6_BOVIN", "mass": { "chemical_mass": 110262.0, "monoisotopic_mass": 110262.0 }, "refseq": { "ac": "NP_001422309", "name": "protein DDI1 homolog 2 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422309" }, "gene_names": [ { "name": "DDI2", "type": "recommended", "evidence": [ { 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"categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422309", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422309", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S0B0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0B0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2W7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2W7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5R1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5R1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYQ6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDNHRSLASYGLKDGDVVILRQKENADPRPSVQFPNLPRIDFRSIAVPGTSNTRQRQPPGVQQSHSAPGEIASSPQGLDNPALLRDMLLANPHELSLLKERNPPLADALLSGDLERFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSKTTFLPEGELPECARLAYGAGRDEVRPEEIADQELAEALQKSVEDAEKSGKETTSLGMSSLPTSDGFNHQAHPPGLSPEIGNPPSLAHSVSASVSPIQPSDADSIEPKAVKALKASAELQITSEQKEHLPPQDLSDCAPSADSAPANQSPAMPLQNSLEEAIVADHVEKSAERSTQGLKSHLHTRQEASLSVTTTGMQEPQRLTGEKVWHPEYQDPSQVSGLQQHEEPRNEHEVIQQSASHDQDHPCHTGDLELLGERQQSSAGLEAAMKGDRLQQNVDLPGTGKDILPSGCLGCSNSETLMEVDIVEQSLVAVPNSGGQNTNVKNSGASDLILDNPLMEVETSKCNPSSEISSNSISTQDLQLLESNVEMSETSKECGDHPSSLISLCGSCQPSVESSEESCSSLTAALKELHELLVISSKPASENTSEEGFCQSETVVEGQTGIKDLSERWTQNEHLTATQSEQCSQVSFHQAISIAVKTEELTDTSADTGVEDGETVNLRGPGDGLLTDKEGVPKSKESVNKSSSVTVASAEASNQLHCTLGVEISPRLLADEEDTLNQTSEQTESSSPACILVKDLGQGTQNPVTDRPEAREHVCPEAAGPLLGLEPSTSHPSPSPSFLAPLIFPAADIDRILRAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT", "length": 1021, "header": "tr|G3MYQ6-1|G3MYQ6_BOVIN Isoform 1 of DNA damage inducible 1 homolog 2 OS=Bos taurus OX=9913 GN=DDI2 PE=3 SV=2 CANONICAL=G3MYQ6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0B0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0B0/entry", "sequence": { "sequence": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDNHRSLASYGLKDGDVVILRQKENADPRPSVQFPNLPRIDFRSIAVPGTSNTRQRQPPGVQQSHSAPGEIASSPQGLDNPALLRDMLLANPHELSLLKERNPPLADALLSGDLERFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSKTTFLPEGELPECARLAYGAGRDEVRPEEIADQELAEALQKSVEDAGPFILEDDIVSVTEQPQL", "length": 412, "header": "tr|A0AAA9S0B0-1|G3MYQ6_BOVIN Computationally mapped isoform of DNA damage inducible 1 homolog 2 OS=Bos taurus OX=9913 GN=DDI2 PE=3 SV=2 CANONICAL=G3MYQ6-1" }, "locus": { "chromosome": "16", "start_pos": 51918404, "end_pos": 51887503, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096778.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096778.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075495.2", "url": "https://www.ensembl.org/id/ENSBTAP00000075495.2" } ] } }, { "isoform_ac": "A0ABI0P2W7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2W7/entry", "sequence": { "sequence": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDNHRSLASYGLKDGDVVILRQKENADPRPSVQFPNLPRIDFRSIAVPGTSNTRQRQPPGVQQSHSAPGEIASSPQGLDNPALLRDMLLANPHELSLLKERNPPLADALLSGDLERFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSKTTFLPEGELPECARLAYGAGRDEVRPEEIADQELAEALQKSVEDAVEIIIGVSDSSGLGRVFHPFLSSGVSFLKQDLSYLCLPCQDRVGHSI", "length": 441, "header": "tr|A0ABI0P2W7-1|A0ABI0P2W7_BOVIN Computationally mapped isoform of DNA damage inducible 1 homolog 2 OS=Bos taurus OX=9913 GN=DDI2 PE=3 SV=1 CANONICAL=G3MYQ6-1" }, "locus": { "chromosome": "16", "start_pos": 51918404, "end_pos": 51880185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145831.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145831.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105254.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105254.1" } ] } }, { "isoform_ac": "A0ABI0P5R1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5R1/entry", "sequence": { "sequence": "MSSLPTSDGFNHQAHPPGLSPEIGNPPSLAHSVSASVSPIQPSDADSIEPKAVKALKASAELQITSEQKEHLPPQDLSDCAPSADSAPANQSPAMPLQNSLEEAIVADHVEKSAERSTQGLKSHLHTRQEASLSVTTTGMQEPQRLTGEKVWHPEYQDPSQVSGLQQHEEPRNEHEVIQQSASHDQDHPCHTGDLELLGERQQSSAGLEAAMKGDRLQQNVDLPGTGKDILPSGCLGCSNSETLMEVDIVEQSLVAVPNSGGQNTNVKNSGASDLILDNPLMEVETSKCNPSSEISSNSISTQDLQLLESNVEMSETSKECGDHPSSLISLCGSCQPSVESSEESCSSLTAALKELHELLVISSKPASENTSEEGFCQSETVVEGQTGIKDLSERWTQNEHLTATQSEQCSQVSFHQAISIAVKTEELTDTSADTGVEDGETVNLRGPGDGLLTDKEGVPKSKESVNKSSSVTVASAEASNQLHCTLGVEISPRLLADEEDTLNQTSEQTESSSPACILVKDLGQGTQNPVTDRPEAREHVCPEAAGPLLGLEPSTSHPSPSPSFLAPLIFPAADIDRILRAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT", "length": 616, "header": "tr|A0ABI0P5R1-1|A0ABI0P5R1_BOVIN Computationally mapped isoform of DNA damage inducible 1 homolog 2 OS=Bos taurus OX=9913 GN=DDI2 PE=4 SV=1 CANONICAL=G3MYQ6-1" }, "locus": { "chromosome": "16", "start_pos": 51883249, "end_pos": 51881402, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141869.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141869.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107577.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107577.1" } ] } }, { "isoform_ac": "G3MYQ6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6/entry", "sequence": { "sequence": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDNHRSLASYGLKDGDVVILRQKENADPRPSVQFPNLPRIDFRSIAVPGTSNTRQRQPPGVQQSHSAPGEIASSPQGLDNPALLRDMLLANPHELSLLKERNPPLADALLSGDLERFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSKTTFLPEGELPECARLAYGAGRDEVRPEEIADQELAEALQKSVEDAEKSGKETTSLGMSSLPTSDGFNHQAHPPGLSPEIGNPPSLAHSVSASVSPIQPSDADSIEPKAVKALKASAELQITSEQKEHLPPQDLSDCAPSADSAPANQSPAMPLQNSLEEAIVADHVEKSAERSTQGLKSHLHTRQEASLSVTTTGMQEPQRLTGEKVWHPEYQDPSQVSGLQQHEEPRNEHEVIQQSASHDQDHPCHTGDLELLGERQQSSAGLEAAMKGDRLQQNVDLPGTGKDILPSGCLGCSNSETLMEVDIVEQSLVAVPNSGGQNTNVKNSGASDLILDNPLMEVETSKCNPSSEISSNSISTQDLQLLESNVEMSETSKECGDHPSSLISLCGSCQPSVESSEESCSSLTAALKELHELLVISSKPASENTSEEGFCQSETVVEGQTGIKDLSERWTQNEHLTATQSEQCSQVSFHQAISIAVKTEELTDTSADTGVEDGETVNLRGPGDGLLTDKEGVPKSKESVNKSSSVTVASAEASNQLHCTLGVEISPRLLADEEDTLNQTSEQTESSSPACILVKDLGQGTQNPVTDRPEAREHVCPEAAGPLLGLEPSTSHPSPSPSFLAPLIFPAADIDRILRAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT", "length": 1021, "header": "tr|G3MYQ6-1|G3MYQ6_BOVIN Isoform 1 of DNA damage inducible 1 homolog 2 OS=Bos taurus OX=9913 GN=DDI2 PE=3 SV=2 CANONICAL=G3MYQ6-1" }, "locus": { "chromosome": "16", "start_pos": 51918404, "end_pos": 51881402, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055483.4", "url": "https://www.ensembl.org/id/ENSBTAT00000055483.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054693.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054693.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515551", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y0Y2-1", "protein_name": "DNA damage inducible 1 homolog 2", "gene_name": "Ddi2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDNHRSLASYGLKDGDVVILRQKENADPRPSVQFSNLPRIDFSSIAVPGTSNPQQRQLPRTQAQLLSPGERTSTPQGLDSPALLRDMLLANPHELSLLKERNPPLAEALLSGDLEKFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVAMLYINCRVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLACSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSQTTFLPEGELPECARLAYGTGREDIRPEEIADQELAEAIQKSAEDAEKSSKESTSLGTPSLLTSEGLNHPAPSGHSPEVGSPTSLARSVSASVCAIKPSDPNSIGSPAVEATKASAEFQTNSKKTDPPLQVLPDLASSAERSLAMPLHNSSDEAFVTGNLEKSAEKRTQGLRVYLHTRQDASLSLTTTGTHEPQIFVEEKSWHPENQNSSQVNGLQQHRETERVQREPGAQSVPGDRECLCHTEDLELQEEAVGWEAVMKGSGALLSTAHLLSAEEGLPAPGRCSCSCSEALMEVDTAEQSPVASCNSTGRPVITSPGVSHVTSEHPSMEVETSQCNLSCDRVEHSILTRDLQLPDNVEMSTMDNKDDRSSSPLSGHGQPSLESAEEFCSSVTVALKELHELLVISCKPASEDSPEDITCQSEIAAESQASISDLTGRSTQSEHLTPSDQHPQVSCPQATSESEKTEILGAAPHAAGEDDTSTGFGGLGDGLSPGQEGLPRSTESVRKSCSVAITSAKLSEQLPCTSGVESSLELAAGEEGAHSQPSEHVQNPGPDRPETSTVCPGAVLPFGGLDQPTTQSLSTPSTLPPFVFPAADVDRILGAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT", "length": 986 }, "evidence": [ { "id": "G3MYQ6", "url": "https://omabrowser.org/oma/group/G3MYQ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" } ], "pmid": "" }, { "name": "regulation of DNA stability", "id": "GO:0097752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097752", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" } ], "pmid": "" }, { "name": "cellular response to hydroxyurea", "id": "GO:0072711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072711", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ6", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 909, "end_pos": 911, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYQ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1021, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYQ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYQ6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 981, "end_pos": 1015, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MYQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ6" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 81, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 775, "end_pos": 777 }, { "start_pos": 872, "end_pos": 874 }, { "start_pos": 909, "end_pos": 911 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7E2-1", "uniprot_ac": "G3X7E2", "uniprot_id": "G3X7E2_BOVIN", "mass": { "chemical_mass": 99249.0, "monoisotopic_mass": 99249.0 }, "refseq": {}, "gene_names": [ { "name": "PPP6R2", "type": "recommended", "evidence": [ { "id": "G3X7E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7E2" } ] } ], "protein_names": [ { "name": "Protein phosphatase 6 regulatory subunit 2", "type": "synonym", "evidence": [ { "id": "G3X7E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7E2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7E2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPP6R2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2", "locus": { "chromosome": "5", "start_pos": 119752795, "end_pos": 119691075, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018660", "url": "https://www.ensembl.org/id/ENSBTAG00000018660" } ] } } ], "crossref": [ { "id": "G3X7E2", "url": "https://alphafold.ebi.ac.uk/entry/G3X7E2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018660", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018660", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3X7E2", "url": "https://www.orthodb.org/?gene=G3X7E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12634:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12634:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S0G6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0G6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKN8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKN8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7E2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7E2-1", "url": "https://www.uniprot.org/uniprotkb/G3X7E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFWKFDLSAMSHVDKLLDKEGVTLRELMDGEDILQECKAQNRKLLDFLCRRQSMEELVGLVTQDPALDLEERARFKYPNTACELLTCDVPQINDRLGGDETLLNVLYNFLDREPPLNPLLASFFSKTIGNLIARKTEQVIAFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKTIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQGSQLLEAPQPDPLLTVLESQECVEQLLRNMFDGVQTELCLVSGTQVLLTLLEPRRAGSEGLLDSCSQGLDRPCTVSPGVLRGIEPRLKDFHQLLLSPPKKAAILTTVGVLEEPLGNARLHSARLVAALLHTGTPSINQELCRLDTMGLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREDRAAASGPEDALEPPPSSGDPAAPQPASSLPEGTMVTHLFQKCCLVQRILEAWEANDRTQAAGGMRRGNMGHLTRIANAVVQNLEGGPLQSQVSEVFRGLPADCRGRWESFVEETLSEANRRNAVDLVSTHHLHPSSEDEDMEGVLPSELSLQQAFSEYQVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEISFTVDADDDSPGAALFEACCSDHIQPFDEDDDLWEAEETHRAARVTRARFGGPHASERCPKDGPERRGQGAGEGVGAVQAGSPCEGGSEGSSWAVFDGPVTPMAASPAPAVARDVGSSVWAAGSPSTSAPEEKGWAKFADFQPFCCSESGPRCSSPVDTGHGDTQAGLNQGPERAPLPRLAVGAWSTCVPRKAPLVAASSREDEQKAAAALEAVGVGPSQKASPLSVGPQVSRADCAPSSPPGPAPLDPAEAPTAPAEAAVTGPAPRAISPVLAVAIPPGPMVAVTTAAPASPAVSMAAALGTVTRDRQAGGPPPSGAALNGPV", "length": 925, "header": "tr|G3X7E2-1|G3X7E2_BOVIN Isoform 1 of Protein phosphatase 6 regulatory subunit 2 OS=Bos taurus OX=9913 GN=PPP6R2 PE=3 SV=4 CANONICAL=G3X7E2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0G6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0G6/entry", "sequence": { "sequence": "MFGCGSSGSKRLSHVPEATQRVPGGVCTGLVTAPRGGLWMPRGVRYPNTACELLTCDVPQINDRLGGDETLLNVLYNFLDREPPLNPLLASFFSKTIGNLIARKTEQVIAFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKTIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQGSQLLEAPQPDPLLTVLESQECVEQLLRNMFDGVQTELCLVSGTQVLLTLLEPRRAGSEGLLDSCSQGLDRPCTVSPGVLRGIEPRLKDFHQLLLSPPKKAAILTTVGVLEEPLGNARLHSARLVAALLHTGTPSINQELCRLDTMGLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREDRAAASGPEDALEPPPSSGDPAAPQPASSLPEGTMVTHLFQKCCLVQRILEAWEANDRTQAAGGMRRGNMGHLTRIANAVVQNLEGGPLQSQVSEVFRGLPADCRGRWESFVEETLSEANRRNAVDLVSTHHLHPSSEDEDMEGVLPSELSLQQAFSEYQVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEISFTVDADDDSPGAALFEACCSDHIQPFDEDDDLWEAEETHRAARVTRARFGGPHASERCPKDGPERRGQGAGEGVGAVQAGSPCEGGSEAGSSWAVFDGPVTPMAASPAPAVARDVGSSVWAAGSPSTSAPEEKGWAKFADFQPFCCSESGPRCSSPVDTGHGDTQAGLNQGPERALGAWSTCVPRKAPLVAASSREDEQKAAAALEAVGVGPSQKASPLSMSGPRADCAPSSPPGPAPLDPAEAPTAPAEAAVTGPAPRAISPVLAVAIPPGPMVAVTTAAPASPAVSMAAALGTVTRDRQAGGPPPSGAALNGPV", "length": 887, "header": "tr|A0AAA9S0G6-1|G3X7E2_BOVIN Computationally mapped isoform of Protein phosphatase 6 regulatory subunit 2 OS=Bos taurus OX=9913 GN=PPP6R2 PE=3 SV=1 CANONICAL=G3X7E2-1" }, "locus": { "chromosome": "5", "start_pos": 119751791, "end_pos": 119726639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089913.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089913.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076814.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076814.1" } ] } }, { "isoform_ac": "A0AAA9TKN8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKN8/entry", "sequence": { "sequence": "MFWKFDLSAMSHVDKLLDKEGVTLRELMDGEDILQECKAQNRKLLDFLCRRQSMEELVGLVTQDPALDLEERARFKYPNTACELLTCDVPQINDRLGGDETLLNVLYNFLDREPPLNPLLASFFSKTIGNLIARKTEQVIAFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKTIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQGSQLLEAPQPDPLLTVLESQECVEQLLRNMFDGVQTELCLVSGTQVLLTLLEPRRAGSEGLLDSCSQGLDRPCTVSPGVLRGIEPRLKDFHQLLLSPPKKAAILTTVGVLEEPLGNARLHSARLVAALLHTGTPSINQELCRLDTMGLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREDRAAASGPEDALEPPPSSGDPAAPQPASSLPEGTMVTHLFQKCCLVQRILEAWEANDRTQAAGGMRRGNMGHLTRIANAVVQNLEGGPLQSQVSEVFRGLPADCRGRWESFVEETLSEANRRNAVDLAFSEYQVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEISFTVDADDDSPGAALFEACCSDHIQPFDEDDDLWEAEETHRAARVTRARFGGPHASERCPKDGPERRGQGAGEGVGAVQAGSPCEGGSEAGSSWAVFDGPVTPMAASPAPAVARDVGSSVWAAGSPSTSAPEEKGWAKFADFQPFCCSESGPRCSSPVDTGHGDTQAGLNQGPERALGAWSTCVPRKAPLVAASSREDEQKAAAALEAVGVGPSQKASPLSVGPQVSRADCAPSSPPGPAPLDPAEAPTAPAEAAVTGPAPRAISPVLAVAIPPGPMVAVTTAAPASPAVSMAAALGTVTRDRLVGRRPQEPPSMAPCDAAAAQSWHPAQKSTW", "length": 908, "header": "tr|A0AAA9TKN8-1|G3X7E2_BOVIN Computationally mapped isoform of Protein phosphatase 6 regulatory subunit 2 OS=Bos taurus OX=9913 GN=PPP6R2 PE=3 SV=2 CANONICAL=G3X7E2-1" }, "locus": { "chromosome": "5", "start_pos": 119751840, "end_pos": 119720294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091676.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091676.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097517.2", "url": "https://www.ensembl.org/id/ENSBTAP00000097517.2" } ] } }, { "isoform_ac": "G3X7E2-1", "url": "https://www.uniprot.org/uniprotkb/G3X7E2/entry", "sequence": { "sequence": "MFWKFDLSAMSHVDKLLDKEGVTLRELMDGEDILQECKAQNRKLLDFLCRRQSMEELVGLVTQDPALDLEERARFKYPNTACELLTCDVPQINDRLGGDETLLNVLYNFLDREPPLNPLLASFFSKTIGNLIARKTEQVIAFLRKKDKFISLVLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKTIQRLVELIHPSQDEDRQSNASQTLCDIIRLGREQGSQLLEAPQPDPLLTVLESQECVEQLLRNMFDGVQTELCLVSGTQVLLTLLEPRRAGSEGLLDSCSQGLDRPCTVSPGVLRGIEPRLKDFHQLLLSPPKKAAILTTVGVLEEPLGNARLHSARLVAALLHTGTPSINQELCRLDTMGLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREDRAAASGPEDALEPPPSSGDPAAPQPASSLPEGTMVTHLFQKCCLVQRILEAWEANDRTQAAGGMRRGNMGHLTRIANAVVQNLEGGPLQSQVSEVFRGLPADCRGRWESFVEETLSEANRRNAVDLVSTHHLHPSSEDEDMEGVLPSELSLQQAFSEYQVQQMTATFVDQFGFSDEEFAEQDDSVNAPFDRIAEISFTVDADDDSPGAALFEACCSDHIQPFDEDDDLWEAEETHRAARVTRARFGGPHASERCPKDGPERRGQGAGEGVGAVQAGSPCEGGSEGSSWAVFDGPVTPMAASPAPAVARDVGSSVWAAGSPSTSAPEEKGWAKFADFQPFCCSESGPRCSSPVDTGHGDTQAGLNQGPERAPLPRLAVGAWSTCVPRKAPLVAASSREDEQKAAAALEAVGVGPSQKASPLSVGPQVSRADCAPSSPPGPAPLDPAEAPTAPAEAAVTGPAPRAISPVLAVAIPPGPMVAVTTAAPASPAVSMAAALGTVTRDRQAGGPPPSGAALNGPV", "length": 925, "header": "tr|G3X7E2-1|G3X7E2_BOVIN Isoform 1 of Protein phosphatase 6 regulatory subunit 2 OS=Bos taurus OX=9913 GN=PPP6R2 PE=3 SV=4 CANONICAL=G3X7E2-1" }, "locus": { "chromosome": "5", "start_pos": 119751791, "end_pos": 119720294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024829.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024829.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024829.8", "url": "https://www.ensembl.org/id/ENSBTAP00000024829.8" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 702, "start_aa": "Thr", "end_pos": 702, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr702", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 855, "start_aa": "Thr", "end_pos": 855, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr855", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "G3X7E2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "G3X7E2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7E2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3X7E2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "G3X7E2", "url": "https://www.uniprot.org/uniprotkb/G3X7E2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7E2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 925, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7E2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7E2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 702, 855 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6REA4-1", "uniprot_ac": "F6REA4", "uniprot_id": "F6REA4_BOVIN", "mass": { "chemical_mass": 45464.0, "monoisotopic_mass": 45464.0 }, "refseq": { "ac": "XP_005222999", "name": "aminoacylase-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222999" }, "gene_names": [ { "name": "ACY1", "type": "recommended", "evidence": [ { "id": "F6REA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ] }, { "name": "ACY1", "type": "synonym", "evidence": [ { "id": "XP_005222999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222999" } ] } ], "protein_names": [ { "name": "N-acyl-aliphatic-L-amino acid amidohydrolase", "type": "recommended", "evidence": [ { "id": "F6REA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REA4/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.14", "type": "synonym", "evidence": [ { "id": "F6REA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REA4/entry#names_and_taxonomy" } ] }, { "name": "N-acyl-L-amino-acid amidohydrolase", "type": "synonym", "evidence": [ { "id": "F6REA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REA4/entry#names_and_taxonomy" } ] }, { "name": "aminoacylase-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005222999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222999" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACY1", "url": "https://www.uniprot.org/uniprotkb/F6REA4", "locus": { "chromosome": "22", "start_pos": 48948307, "end_pos": 48953164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032304", "url": "https://www.ensembl.org/id/ENSBTAG00000032304" } ] } } ], "crossref": [ { "id": "F6REA4", "url": "https://alphafold.ebi.ac.uk/entry/F6REA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032304", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032304", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05646", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05646", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768058", "url": "https://www.ncbi.nlm.nih.gov/gene/768058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MDCVETI", "url": "https://omabrowser.org/oma/group/MDCVETI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MR63", "url": "https://www.orthodb.org/?gene=F1MR63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45892", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45892", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45892:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45892:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5423646", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5423646", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005222999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15565", "url": "https://www.rhea-db.org/rhea/15565", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S2B5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2B5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXR9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXR9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH33", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH33-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRT9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRT9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MR63", "url": "https://www.uniprot.org/uniprotkb/F1MR63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MR63-1", "url": "https://www.uniprot.org/uniprotkb/F1MR63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6REA4-1", "url": "https://www.uniprot.org/uniprotkb/F6REA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEGREGEHPSVTLFRQYLRIRTLQPEPDYGAAVAFFEERALQLGLGCQKVEVAPGRVVTVLTWPGTNPKLSSVLLNSHTDVVPVFQEYWSHDPFEAFKDADGYIYGRGAQDMKCVSIQYLEAVRRLKAEGHHFPRTIHLTFVPDEEIGGHQGMELFVKRPEFQALRAGFALDEGLANPTDAFTVFYSERSPWWVRVTSTGKPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSDPQLKEGAVTSVNLTILEGGVAYNVVPATMSASFDFRVAPDVDLKAFEGQLQDWCQAAGEGVTFEFAQKWTEPQVTPTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNRTPILLHDHDERLHEAVFLRGVDIYTRLLPALASVPVLPSES", "length": 408, "header": "tr|F6REA4-1|F6REA4_BOVIN Isoform 1 of N-acyl-aliphatic-L-amino acid amidohydrolase OS=Bos taurus OX=9913 GN=ACY1 PE=1 SV=1 CANONICAL=F6REA4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2B5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2B5/entry", "sequence": { "sequence": "MQRSLVDEELCGGAAVAFFEERALQLGLGCQKVEVAPGRVVTVLTWPGTNPKLSSVLLNSHTDVVPVFQEYWSHDPFEAFKDADGYIYGRGAQDMKCVSIQYLEAVRRLKAEGHHFPRTIHLTFVPDEEIGGHQGMELFVKRPEFQALRAGFALDEGLANPTDAFTVFYSERSPWWVRVTSTGKPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSDPQLKEGAVTSVNLTILEGGVAYNVVPATMSASFDFRVAPDVDLKAFEGQLQDWCQAAGEGVTFEFAQKWTEPQVTPTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNRTPILLHDHDERLHEAVFLRGVDIYTRLLPALASVPVLPSES", "length": 389, "header": "tr|A0AAA9S2B5-1|F6REA4_BOVIN Computationally mapped isoform of N-acyl-aliphatic-L-amino acid amidohydrolase OS=Bos taurus OX=9913 GN=ACY1 PE=1 SV=1 CANONICAL=F6REA4-1" }, "locus": { "chromosome": "22", "start_pos": 48951940, "end_pos": 48948396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093506.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093506.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077449.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077449.1" } ] } }, { "isoform_ac": "A0AAA9SXR9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXR9/entry", "sequence": { "sequence": "MASEGREGEHPSVTLFRQYLRIRTLQPEPDYGAAVAFFEERALQLGLGCQKVEVAPGRVVTVLTWPGTNPKLSSVLLNSHTDVVPVFQEYWSHDPFEAFKDADGYIYGRGAQDMKCVSIQYLEAVRRLKAEGHHFPRTIHLTFVPDEEIGGHQGMELFVKRPEFQALRAGFALDEGLANPTDAFTVFYSERSPWWVRVTSTGKPGHGSRFIEDTAAEKLAFEGQLQDWCQAAGEGVTFEFAQKWTEPQVTPTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNRTPILLHDHDERLHEAVFLRGVDIYTRLLPALASVPVLPSES", "length": 343, "header": "tr|A0AAA9SXR9-1|F6REA4_BOVIN Computationally mapped isoform of N-acyl-aliphatic-L-amino acid amidohydrolase OS=Bos taurus OX=9913 GN=ACY1 PE=1 SV=1 CANONICAL=F6REA4-1" }, "locus": { "chromosome": "22", "start_pos": 48952706, "end_pos": 48948396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125098.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125098.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088106.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088106.1" } ] } }, { "isoform_ac": "A0AAA9TH33-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH33/entry", "sequence": { "sequence": "MASEGREGEHPSVTLFRQYLRIRTLQPEPDYGTNPKLSSVLLNSHTDVVPVFQEYWSHDPFEAFKDADGYIYGRGAQDMKCVSIQYLEAVRRLKAEGHHFPRTIHLTFVPDEEIGGHQGMELFVKRPEFQALRAGFALDEGLANPTDAFTVFYSERSPWWVRVTSTGKPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSDPQLKEGAVTSVNLTILEGGVAYNVVPATMSASFDFRVAPDVDLKAFEGQLQDWCQAAGEGVTFEFAQKWTEPQVTPTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNRTPILLHDHDERLHEAVFLRGVDIYTRLLPALASVPVLPSES", "length": 373, "header": "tr|A0AAA9TH33-1|F6REA4_BOVIN Computationally mapped isoform of N-acyl-aliphatic-L-amino acid amidohydrolase OS=Bos taurus OX=9913 GN=ACY1 PE=1 SV=1 CANONICAL=F6REA4-1" }, "locus": { "chromosome": "22", "start_pos": 48952706, "end_pos": 48948396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112520.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112520.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097535.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097535.1" } ] } }, { "isoform_ac": "A0AAA9TRT9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRT9/entry", "sequence": { "sequence": "MASEGREGEHPSVTLFRQYLRIRTLQPEPDYGAAVAFFEERALQLGLGCQKVEVAPGRVVTVLTWPGTNPKLSSVLLNSHTDVVPVFQEYWSHDPFEAFKDADGLANPTDAFTVFYSERSPWWVRVTSTGKPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSDPQLKEGAVTSVNLTILEGGVAYNVVPATMSASFDFRVAPDVDLKAFEGQLQDWCQAAGEGVTFEFAQKWTEPQVTPTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNRTPILLHDHDERLHEAVFLRGVDIYTRLLPALASVPVLPSES", "length": 336, "header": "tr|A0AAA9TRT9-1|F6REA4_BOVIN Computationally mapped isoform of N-acyl-aliphatic-L-amino acid amidohydrolase OS=Bos taurus OX=9913 GN=ACY1 PE=1 SV=1 CANONICAL=F6REA4-1" }, "locus": { "chromosome": "22", "start_pos": 48952706, "end_pos": 48948396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133618.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133618.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101303.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101303.1" } ] } }, { "isoform_ac": "F1MR63-1", "url": "https://www.uniprot.org/uniprotkb/F1MR63/entry", "sequence": { "sequence": "MFREGKDDTCFSLWTCHLAFHKGSLAKKHLPWGPRCKGLLWMRNCVEAGVCSPLWMSPHLCLGPWEVRMGGEAEAAARLSVSPGAAVAFFEERALQLGLGCQKVEEYWSHDPFEAFKDADGYIYGRGAQDMKCVSIQYLEAVRRLKAEGHHFPRTIHLTFVPDEEIGGHQGMELFVKRPEFQALRAGFALDEGLANPTDAFTVFYSERSPWWVRVTSTGKPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSDPQLKEGAVTSVNLTILEGGVAYNVVPATMSASFDFRVAPDVDLKAFEGQLQDWCQAAGEGVTFEFAQKWTEPQVTPTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNRTPILLHDHDERLHEAVFLRGVDIYTRLLPALASVPVLPSES", "length": 425, "header": "tr|F1MR63-1|F1MR63_BOVIN Computationally mapped isoform of N-acyl-aliphatic-L-amino acid amidohydrolase OS=Bos taurus OX=9913 GN=ACY1 PE=1 SV=3 CANONICAL=F6REA4-1" }, "locus": { "chromosome": "22", "start_pos": 48952044, "end_pos": 48948396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024787.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024787.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024787.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024787.5" } ] } }, { "isoform_ac": "F6REA4-1", "url": "https://www.uniprot.org/uniprotkb/F6REA4/entry", "sequence": { "sequence": "MASEGREGEHPSVTLFRQYLRIRTLQPEPDYGAAVAFFEERALQLGLGCQKVEVAPGRVVTVLTWPGTNPKLSSVLLNSHTDVVPVFQEYWSHDPFEAFKDADGYIYGRGAQDMKCVSIQYLEAVRRLKAEGHHFPRTIHLTFVPDEEIGGHQGMELFVKRPEFQALRAGFALDEGLANPTDAFTVFYSERSPWWVRVTSTGKPGHGSRFIEDTAAEKLHKVVSSILAFREKERQRLQSDPQLKEGAVTSVNLTILEGGVAYNVVPATMSASFDFRVAPDVDLKAFEGQLQDWCQAAGEGVTFEFAQKWTEPQVTPTDDSDPWWAAFSGACKDMNLTLEPEIFPAATDSRYLRAVGVPALGFSPMNRTPILLHDHDERLHEAVFLRGVDIYTRLLPALASVPVLPSES", "length": 408, "header": "tr|F6REA4-1|F6REA4_BOVIN Isoform 1 of N-acyl-aliphatic-L-amino acid amidohydrolase OS=Bos taurus OX=9913 GN=ACY1 PE=1 SV=1 CANONICAL=F6REA4-1" }, "locus": { "chromosome": "22", "start_pos": 48952706, "end_pos": 48948396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045814.3", "url": "https://www.ensembl.org/id/ENSBTAT00000045814.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043175.2", "url": "https://www.ensembl.org/id/ENSBTAP00000043175.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-5423646", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5423646", "resource": "Reactome", "description": "Aflatoxin activation and detoxification" }, { "id": "R-BTA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58IDX9-1", "protein_name": "N-acyl-aliphatic-L-amino acid amidohydrolase", "gene_name": "acy1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGQWCGMLPDKDGLNGGGGVQDGHPAEDPSVTLFREYLRLKTVHPEPDYDAALKFLERMAEELALPMKKVEVCPGRVVAIISWIGSRPELKSVVLNSHTDVVPVYEEHWKHHPFAAVKDADGNIYARGAQDMKSVTIQYIEAIRRLKAAGKRFSRTIHLTFVPDEEVGGHKGMETFVKHPEFQKLNMGFALDEGLANPTNAYTVFYGERNPWWITVRCPGSPGHGSRFVENTAAEKLRRVINSFLEFREKEKQRLNTSECFTLGDVTTINMTMVKGGVAYNVVPAEMDVSFDLRIPPTVNLQEFEEKIKVWCREAGEDVTYDFAQKHMDQNLTSTDENDPWWQAFSSTCKAMNMTLKKEIFPAATDSRFIREVGLPAIGFSPMNLTPILLHDHNEYLNEQVFLQGIQVYERLIPALAGVAPLSAEL", "length": 427 }, "evidence": [ { "id": "F6REA4", "url": "https://omabrowser.org/oma/group/F6REA4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9I7K3-1", "protein_name": "N-acyl-aliphatic-L-amino acid amidohydrolase", "gene_name": "Dmel\\CG6465", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATSKWESDEEIQYFREYLRIPSVHPDPDYAPCVEFLRRQANLMDLPMKVYYPANEQNPVVVLTWKGLNPELPSILLNSHMDVVPVFPENWTHPPFGADIDEEGRIFARGTQDMKSVGMQHLAAVRALKRSGAKFKRTIHISFVADEEMGGRYGMRPFVPTEDFRALNVGFAMDEGLASPDEQLPLFYAERAVWRVYFNISGTAGHGSLLLPNTAGEKLNYIVGKMMEFRRSQVQRLQNNPELVIGDVTTINLTKLGGGVQSNVVPPLLMVCFDCRLALDVDFEEFEANLHKWCADVGGGIEITYEQKQPKVPPTAIDGSNPFWLAFKKATDEMHISIKPQIFTGGTDSRYIRAVGIPALGFSPMNNTPVLLHDHDEFIQADIYLRGVQIFQKIISNIANV", "length": 401 }, "evidence": [ { "id": "F6REA4", "url": "https://omabrowser.org/oma/group/F6REA4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9LPE9-1", "protein_name": "Peptidase M20/M25/M40 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAISPLLWTLIIFSIIFSLQSSSSEEDTPITRFQQYLRFNTAHPNPNYTAPISFLINQAQSIGLTTKTIEFISGKPILLITWLGSNPNLPSILFNSHLDSVPAESEKWTYPPFSAHKTIDGHIYARGAQDDKCIGVQYLESIRNLKSRGFSPLRTIHISYVPEEEIGGFDGMMKFAASSEFKDLNLGFAMDEGQANPGDEFRVFYADRVPWHFVIKAEGIPGHGAKLYDNSAMENLMKSVELISRFRESQFDFVKAGKAAYSEVISVNPVYLKAGTPTTTGFVMNMQPSEAEAGYDLRLPPMADPDVMKKRIAEEWAPSIRNMTYSIQEKGKLRDHLGRPIMTPVNDSNPWWSIFKQAVEAMGGKLAKPEILASTTDSRFIRTLGIPTFGFSPMTNTPILLHDHNEFLKDTVFMKGIEVYESVISALSSFEGESAQVI", "length": 438 }, "evidence": [ { "id": "F6REA4", "url": "https://omabrowser.org/oma/group/F6REA4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "aminoacylase activity", "id": "GO:0004046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004046", "evidence": [ { "database": "UniProtKB", "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "F6REA4", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15565", "name": "", "equation": "an N-acyl-L-amino acid + H2O = an L-alpha-amino acid + a carboxylate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJX8-1", "Q2T9M7-1", "F6REA4-1" ], "evidence": [ { "id": "15565", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15565" } ] }, { "id": "R-BTA-5433074", "name": "ACY1:Zn2+ dimer hydrolyses mercapturic acids", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-9717939" ], "enzyme_list": [ "F6REA4-1" ], "evidence": [ { "id": "R-BTA-5433074", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5433074" } ] }, { "id": "R-BTA-9753944", "name": "ACY1:Zn2+ dimer deacetylates NAC to L-Cys", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9753926" ], "output_participant_list": [], "enzyme_list": [ "F6REA4-1" ], "evidence": [ { "id": "R-BTA-9753944", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753944" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9717939", "participant_name": "acetate [cytosol]", "crossref": [ { "id": "30089", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9753926", "participant_name": "NAC [cytosol]", "crossref": [ { "id": "78236", "database": "ChEBI", "url": "" }, { "id": "ZINC000003589203", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BJX8", "gene_name": "PM20D1", "activity": [ { "ec_number": "3.5.1.114", "activity": "an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate.", "evidence": [ { "id": "E1BJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX8" } ] }, { "ec_number": "3.5.1.14", "activity": "an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate.", "evidence": [ { "id": "E1BJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX8" } ] }, { "ec_number": "3.5.1.114", "activity": "", "evidence": [ { "id": "E1BJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX8" } ] }, { "ec_number": "3.5.1.14", "activity": "", "evidence": [ { "id": "E1BJX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX8" } ] } ] }, { "uniprot_ac": "F6REA4", "gene_name": "ACY1", "activity": [ { "ec_number": "3.5.1.14", "activity": "an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate.", "evidence": [ { "id": "F6REA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ] }, { "ec_number": "3.5.1.14", "activity": "", "evidence": [ { "id": "F6REA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6REA4" } ] } ] }, { "uniprot_ac": "Q2T9M7", "gene_name": "PM20D1", "activity": [ { "ec_number": "3.5.1.114", "activity": "an N-acyl-aromatic L-alpha-amino acid + H2O = an aromatic L-alpha-amino acid + a carboxylate.", "evidence": [ { "id": "Q2T9M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9M7" } ] }, { "ec_number": "3.5.1.14", "activity": "an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate.", "evidence": [ { "id": "Q2T9M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9M7" } ] }, { "ec_number": "3.5.1.14", "activity": "", "evidence": [ { "id": "Q2T9M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9M7" } ] }, { "ec_number": "3.5.1.114", "activity": "", "evidence": [ { "id": "Q2T9M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9M7" } ] } ] } ], "biomarkers": [], "structures": [], 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", 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], "gene": [ { "name": "ARHGAP1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1", "locus": { "chromosome": "15", "start_pos": 76622892, "end_pos": 76639557, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016501", "url": "https://www.ensembl.org/id/ENSBTAG00000016501" } ] } } ], "crossref": [ { "id": "F6RWK1", "url": "https://alphafold.ebi.ac.uk/entry/F6RWK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016501", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016501", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04404", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04404", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512817", "url": "https://www.ncbi.nlm.nih.gov/gene/512817", "database": 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"Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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{ "id": "A0AAA9SMB1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4Q3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWK1-1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPLSELQDDLTLDDPSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSFSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQQLREKNPEQQPIPLVLRETVAYLRAHALTTEGIFRRSANTQVVREVQHKYNMGLSVDFEQYNELHLPAVILKTFLRELPEPLLTFDLYSHVVGFLNIDESQRVKATLQALQTLPEENYLVLRFLTAFLVQISALSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 439, "header": "tr|F6RWK1-1|F6RWK1_BOVIN Isoform 1 of Rho GTPase activating protein 1 OS=Bos taurus OX=9913 GN=ARHGAP1 PE=1 SV=1 CANONICAL=F6RWK1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S4E1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4E1/entry", "sequence": { "sequence": "MDPLSELQDDLTLDDPSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSFSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQQLREKNPEQQPIPLVLRETVAYLRAHGLSVDFEQYNELHLPAVILKTFLRELPEPLLTFDLYSHVVGFLNIDESQRVKATLQALQTLPEENYLVLRFLTAFLVQISALSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 413, "header": "tr|A0AAA9S4E1-1|F6RWK1_BOVIN Computationally mapped isoform of Rho GTPase activating protein 1 OS=Bos taurus OX=9913 GN=ARHGAP1 PE=1 SV=1 CANONICAL=F6RWK1-1" }, "locus": { "chromosome": "15", "start_pos": 76638674, "end_pos": 76624354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125558.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125558.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080804.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080804.1" } ] } }, { "isoform_ac": "A0AAA9SMB1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMB1/entry", "sequence": { "sequence": "MDPLSELQDDLTLDDPSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGCDEPEGAQPGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSFSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQQLREKNPEQQPIPLVLRETVAYLRAHALTTEGIFRRSANTQVVREVQHKYNMGLSVDFEQYNELHLPAVILKTFLRELPEPLLTFDLYSHVVGFLNIDESQRVKATLQALQTLPEENYLVLRFLTAFLVQISALSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 449, "header": "tr|A0AAA9SMB1-1|F6RWK1_BOVIN Computationally mapped isoform of Rho GTPase activating protein 1 OS=Bos taurus OX=9913 GN=ARHGAP1 PE=1 SV=1 CANONICAL=F6RWK1-1" }, "locus": { "chromosome": "15", "start_pos": 76638674, "end_pos": 76624354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134085.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134085.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086427.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086427.1" } ] } }, { "isoform_ac": "A0AAA9T4Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4Q3/entry", "sequence": { "sequence": "MDPLSELQDDLTLDDPSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSFSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQQLREKNPEQQPIPLVLRETVAYLRAHALTTEGIFRRSANTQVVREVQHKYNMDIDESQRVKATLQALQTLPEENYLVLRFLTAFLVQISALSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 396, "header": "tr|A0AAA9T4Q3-1|F6RWK1_BOVIN Computationally mapped isoform of Rho GTPase activating protein 1 OS=Bos taurus OX=9913 GN=ARHGAP1 PE=1 SV=1 CANONICAL=F6RWK1-1" }, "locus": { "chromosome": "15", "start_pos": 76638674, "end_pos": 76624354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090700.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090700.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090705.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090705.1" } ] } }, { "isoform_ac": "F6RWK1-1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1/entry", "sequence": { "sequence": "MDPLSELQDDLTLDDPSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSFSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQQLREKNPEQQPIPLVLRETVAYLRAHALTTEGIFRRSANTQVVREVQHKYNMGLSVDFEQYNELHLPAVILKTFLRELPEPLLTFDLYSHVVGFLNIDESQRVKATLQALQTLPEENYLVLRFLTAFLVQISALSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 439, "header": "tr|F6RWK1-1|F6RWK1_BOVIN Isoform 1 of Rho GTPase activating protein 1 OS=Bos taurus OX=9913 GN=ARHGAP1 PE=1 SV=1 CANONICAL=F6RWK1-1" }, "locus": { "chromosome": "15", "start_pos": 76638674, "end_pos": 76624354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043933.4", "url": "https://www.ensembl.org/id/ENSBTAT00000043933.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041467.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041467.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512817", "resource": "KEGG Pathway" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-BTA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-BTA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-BTA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-BTA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-BTA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" }, { "id": "R-BTA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYR5-1", "protein_name": "Rho GTPase activating protein 1", "gene_name": "Arhgap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLKDRTGSLEVIAGSGRSTRKAMFGPGSKPEVGRRYGGSGWELRAPEGAVPIPTSEPDVCRALTGVAKGALPERGELQSAGSHWAWWLLFWFSLAMDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLREKNPNQEPIPIVLRETVAYLQAHALTAEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHIVGFLDLDDDQRVEVTQQVLQTLPEENYRVLHFLTAFLVQVSAHSYQNRMNNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSTDAQGV", "length": 535 }, "evidence": [ { "id": "F6RWK1", "url": "https://omabrowser.org/oma/group/F6RWK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A5G2QDJ1-1", "protein_name": "Rho GTPase activating protein 1", "gene_name": "ARHGAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPLSELQDDLTVDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPIISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLREKNPDQEPIPLVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYSHVVGFLSIDESQRVQATLQVFQTLPEENYLVLRFLTAFLVQISALCDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDAKGL", "length": 439 }, "evidence": [ { "id": "F6RWK1", "url": "https://omabrowser.org/oma/group/F6RWK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZTR7-1", "protein_name": "Rho GTPase activating protein 1", "gene_name": "ARHGAP1", "tax_id": 9031, "organism": 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"MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL", "length": 439 }, "evidence": [ { "id": "F6RWK1", "url": "https://omabrowser.org/oma/group/F6RWK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5FWK3-1", "protein_name": "Rho GTPase-activating protein 1", "gene_name": "Arhgap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPLSELQDDLTLDDTSQALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPEPVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGRKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKSPGQDPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVEVTQQVLQTLPEENYQVLHFLTAFLVQISAHCDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSTDAQGV", "length": 439 }, "evidence": [ { "id": "F6RWK1", "url": "https://omabrowser.org/oma/group/F6RWK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTU3-1", "protein_name": "Rho GTPase-activating protein 68F", "gene_name": "RhoGAP68F", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDAHSRFAPRLPGPAINPIVDNSDEPQPSLSDLHDFEPKLEFDDTELLAPSPLEKDVMVGDFVLAEDPELEPEEDVNPLEDDFEDQLREQSENFQTPRNKCDFLGTDKQGRHIFGIYASRFPEKSQLEGFVREIIKEIEPFVENDYILVYFHQGLKEDNKPSAQFLWNSYKELDRNFRKNLKTLYVVHPTWFIRVIWNFFSPFISDKFRKKLVYISSLDELRQALGLNKLKLPDNICDLDDKLNPSRKPSTPPPSSNINASRQQQHKMATTHQFGVPLKFIVMNSPCLNSIPPIVRKCVDSLSITGVIDTEGIFRRSGNHSEIMALKERVNRGEDVDLKSVNVHVIAGLLKSFLRDLAEPLLTFELYEDVTGFLDWPKEERSRNVTQLIREKLPEENYELFKYIVEFLVRVMDCEDLNKMTSSNLAIVFGPNFLWSRSTSTSLEEIAPINAFVDFVLQNHKDIYLIDVNQRTVSVD", "length": 476 }, "evidence": [ { "id": "F6RWK1", "url": "https://omabrowser.org/oma/group/F6RWK1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "transferrin transport", "id": "GO:0033572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033572", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "negative regulation of endocytic recycling", "id": "GO:2001136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001136", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "sorting endosome", "id": "GO:0097443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097443", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "F6RWK1", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RWK1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 439, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RWK1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RWK1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RWK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 218, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RWK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWK1" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 244, "end_pos": 431, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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{ "name": "PHF7", "url": "https://www.uniprot.org/uniprotkb/G3N059", "locus": { "chromosome": "22", "start_pos": 48466108, "end_pos": 48478983, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047658", "url": "https://www.ensembl.org/id/ENSBTAG00000047658" } ] } } ], "crossref": [ { "id": "G3N059", "url": "https://alphafold.ebi.ac.uk/entry/G3N059", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047658", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047658", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15496", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15496", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15669", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15669", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100337047", "url": "https://www.ncbi.nlm.nih.gov/gene/100337047", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100337047", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337047", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NNRDEFP", "url": "https://omabrowser.org/oma/group/NNRDEFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N059", "url": "https://www.orthodb.org/?gene=G3N059", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12420", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12420:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26054", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26054", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002697069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697069", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S8G2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHQ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZP6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZP6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N059", "url": "https://www.uniprot.org/uniprotkb/G3N059", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N059-1", "url": "https://www.uniprot.org/uniprotkb/G3N059-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSIKEKKKEYQRLRRSAKTKRVTQRKRSSGPVCRLCLQEPGDPEKLGEFLQKDNLSVHYFCLILSSKLPQRGQSNRGFHGFLPEDIRKEAARASRKICFVCKRKGAAINCQKDQCARNFHLPCGLERGCLSQFFGEYKSFCGEHRPTQNIRRRNVGEESCILCCEDLSQISVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYERGRDSSEEEGKWRLILCATCGSHGTHRNCSSLRSNCKKWECMECAPAAKVIEYTLENSGDIPCCSSTFLSRGHFYRDTGLEENPGPSWTNWPGSSLLENPESSGPRRSQSWGSKGVTISKSCKKSE", "length": 383, "header": "tr|G3N059-1|G3N059_BOVIN Isoform 1 of PHD finger protein 7 OS=Bos taurus OX=9913 GN=PHF7 PE=4 SV=3 CANONICAL=G3N059-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S8G2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8G2/entry", "sequence": { "sequence": "MQTTEVLRRSAKTKRVTQRKRSSGPVCRLCLQEPGDPEKLGEFLQKDNLSVHYFCLILSSKLPQRGQSNRGFHGFLPEDIRKEAARASRKICFVCKRKGAAINCQKDQCARNFHLPCGLERGCLSQFFGEYKSFCGEHRPTQNIRRRNVGEESCILCCEDLSQISVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYERGRDSSEEEGKWRLILCATCGSHGTHRNCSSLRSNCKKWECMECAPAAKVIEYTLENSGDIPCCSSTFLSRGHFYRDTGLEENPGPSWTNWPGSSLLENPESSGPRRSQSWGSKGVTISKSCKKSE", "length": 376, "header": "tr|A0AAA9S8G2-1|G3N059_BOVIN Computationally mapped isoform of PHD finger protein 7 OS=Bos taurus OX=9913 GN=PHF7 PE=4 SV=1 CANONICAL=G3N059-1" }, "locus": { "chromosome": "22", "start_pos": 48478322, "end_pos": 48466452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128821.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128821.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082334.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082334.1" } ] } }, { "isoform_ac": "A0AAA9SHQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHQ1/entry", "sequence": { "sequence": "MKSIKEKKKEYQRLRRSAKTKRVTQRKRSSGPVCRLCLQEPGDPEKLGEFLQKDNLSVHYFCLILSSKLPQRGQSNRGFHGFLPEDIRKEAARASRKICFVCKRKGAAINCQKDQCARNFHLPCGLERGCLSQFFGEYKSFCGEHRPTQNIRRRNVGEESCILCCEDLSQISVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRKWRLILCATCGSHGTHRNCSSLRSNCKKWECMECAPAAKVIEYTLENSGDIPCCSSTFLSRGHFYRDTGLEENPGPSWTNWPGSSLLENPESSGPRRSQSWGSKGVTISKSCKKSE", "length": 344, "header": "tr|A0AAA9SHQ1-1|G3N059_BOVIN Computationally mapped isoform of PHD finger protein 7 OS=Bos taurus OX=9913 GN=PHF7 PE=4 SV=1 CANONICAL=G3N059-1" }, "locus": { "chromosome": "22", "start_pos": 48477086, "end_pos": 48466452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096556.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096556.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082037.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082037.1" } ] } }, { "isoform_ac": "A0AAA9TZP6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZP6/entry", "sequence": { "sequence": "ERSAKTKRVTQRKRSSGPVCRLCLQEPGDPEKLGEFLQKDNLSVHYFCLILSSKLPQRGQSNRGFHGFLPEDIRKEAARASRKICFVCKRKGAAINCQKDQCARNFHLPCGLERGCLSQFFGEYKSFCGEHRPTQNIRRRNVGEESCILCCEDLSQISVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYERGRDSSEEEGKWRLILCATCGSHGTHRNCSSLRSNCKKWECMECAPAAKVIEYTLENSGDIPCCSSTFLSRGHFYRDTGLEENPGPSWTNWPGSSLLENPESSGPRRSQSWGSKGVTISKSCKKSE", "length": 369, "header": "tr|A0AAA9TZP6-1|G3N059_BOVIN Computationally mapped isoform of PHD finger protein 7 OS=Bos taurus OX=9913 GN=PHF7 PE=4 SV=1 CANONICAL=G3N059-1" }, "locus": { "chromosome": "22", "start_pos": 48477927, "end_pos": 48466452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109045.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109045.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102763.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102763.1" } ] } }, { "isoform_ac": "G3N059-1", "url": "https://www.uniprot.org/uniprotkb/G3N059/entry", "sequence": { "sequence": "MKSIKEKKKEYQRLRRSAKTKRVTQRKRSSGPVCRLCLQEPGDPEKLGEFLQKDNLSVHYFCLILSSKLPQRGQSNRGFHGFLPEDIRKEAARASRKICFVCKRKGAAINCQKDQCARNFHLPCGLERGCLSQFFGEYKSFCGEHRPTQNIRRRNVGEESCILCCEDLSQISVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYERGRDSSEEEGKWRLILCATCGSHGTHRNCSSLRSNCKKWECMECAPAAKVIEYTLENSGDIPCCSSTFLSRGHFYRDTGLEENPGPSWTNWPGSSLLENPESSGPRRSQSWGSKGVTISKSCKKSE", "length": 383, "header": "tr|G3N059-1|G3N059_BOVIN Isoform 1 of PHD finger protein 7 OS=Bos taurus OX=9913 GN=PHF7 PE=4 SV=3 CANONICAL=G3N059-1" }, "locus": { "chromosome": "22", "start_pos": 48477086, "end_pos": 48466452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063855.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063855.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055215.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055215.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100337047", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337047", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QNT5-1", "protein_name": "E3 ubiquitin-protein ligase PHF7", "gene_name": "Phf7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKTIKEKKKLPRLRKTSRTKKVIQKKLSSSGPVCLLCLQEPGDPEKLGEFLQKESLCVHYFCLILSSKLPQKGQPNRGLHGFMPEDIKKEAVRASKKMCFVCKKKGAAIKCQNDQCVKNFHLPCGQERGCLSQFFGEYKSYCGKHRPTQDIQQGSQREESCVLCCEDLSQTSVENIRSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSSLRPNSKKWECDECSPASTKDYVCEDSSDIPCCSSTFHPQEHFFRASNLEGNPDSSWTEWLQPSLLEKPESSGGRRSHSWRSKGIRIAKNCKKSK", "length": 382 }, "evidence": [ { "id": "G3N059", "url": "https://omabrowser.org/oma/group/G3N059/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SIW4-1", "protein_name": "E3 ubiquitin-protein ligase PHF7", "gene_name": "PHF7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKTIKEKKKKRQRLRKSAKTRRVTQRKPSSGPVCRLCLREPGDPEKLGEFLQKDNLSVHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDHCVRNFHLPCGQERGCLSQFFGEYKSFCGKHRPTQNIQRGNMGEESCVLCCEDLSQASVENIQSPCCSQTIYHRKCIQKYAHTSAKHFFKCPQCNNRDEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYEQGRDSFEDEGRWRLILCTTCGSHGTHRDCSSLRSNCKKWECKECAPSAEATDYTPENSGDMPCCSSTFQSREHFCRDTSLEENPGPSWTDWPGPTLLEKPESSGHRRGGHSWKSKGVKIIKCCKKSK", "length": 384 }, "evidence": [ { "id": "G3N059", "url": "https://omabrowser.org/oma/group/G3N059/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6AXW4-1", "protein_name": "E3 ubiquitin-protein ligase PHF7", "gene_name": "PHD finger protein 7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRTIKEKKEHPRLRKTARTKKVTHRKLSSGPVCLLCFQEPGDPEKLGEFLQKDNLCVHYFCLILSSKLPQKGQPNRGLHGFMPEDIKKEAARASRKVCFVCKRKGAAIRCQKDQCVQNFHLPCGQERGCLSQFFGEYKSYCGKHRPTQNIHQRSFGESCVLCCEDLSRASVENIRSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYQHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSSLRPNSKKWECNECLPASTEDSVSENLGDTPCCSSTFCPHEPFLRATSLEENPGSSWTNWLQPSLLEKPESSSGSSCQSWRSKGIKVTKDCKKSK", "length": 380 }, "evidence": [ { "id": "G3N059", "url": "https://omabrowser.org/oma/group/G3N059/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BWX1-1", "protein_name": "E3 ubiquitin-protein ligase PHF7", "gene_name": "PHF7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKTVKEKKECQRLRKSAKTRRVTQRKPSSGPVCWLCLREPGDPEKLGEFLQKDNISVHYFCLILSSKLPQRGQSNRGFHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEYKSFCDKHRPTQNIQHGHVGEESCILCCEDLSQQSVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRDAAWELEPGAFSDLYQRYQHCDAPICLYEQGRDSFEDEGRWCLILCATCGSHGTHRDCSSLRSNSKKWECEECSPAAATDYIPENSGDIPCCSSTFHPEEHFCRDNTLEENPGLSWTDWPEPSLLEKPESSRGRRSYSWRSKGVRITNSCKKSK", "length": 381 }, "evidence": [ { "id": "G3N059", "url": "https://omabrowser.org/oma/group/G3N059/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAG9-1", "protein_name": "E3 ubiquitin-protein ligase PHF7", "gene_name": "Phf7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLKEKNKHPRLRKTIRTKKVTQRKLSSSPVCLLCLQEPGDPEKLGEFLQKDNLCVHYFCLILSSRLPQKGQPNRGLHGFMPEDIKREAVRASKKICFVCKKKGAAIRCQNDQCVQNFHLPCGQERGCLSQFFGEYKSYCRKHRPTQNIHQGSLGEESCVLCCENLSRTSVENIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDAAWELEPGAFSELYQRYRHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDCSSLRPNSKKWECNECLPASTTS", "length": 307 }, "evidence": [ { "id": "G3N059", "url": "https://omabrowser.org/oma/group/G3N059/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N059", "url": "https://www.uniprot.org/uniprotkb/G3N059" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "G3N059", "url": "https://www.uniprot.org/uniprotkb/G3N059" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N059", "url": "https://www.uniprot.org/uniprotkb/G3N059" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "G3N059", "url": "https://www.uniprot.org/uniprotkb/G3N059" } ], "pmid": "" }, { "name": "histone H3K14 ubiquitin ligase activity", "id": "GO:0140851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140851", "evidence": [ { "database": "UniProtKB", "id": "G3N059", "url": "https://www.uniprot.org/uniprotkb/G3N059" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of osteoclast proliferation", "id": "GO:0090291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090291", "evidence": [ { "database": "UniProtKB", "id": "G3N059", "url": "https://www.uniprot.org/uniprotkb/G3N059" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N059-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 383, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N059-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N059" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N059" }, { "id": "PS51805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 146, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N059" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 161, "end_pos": 209, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZR3-1", "uniprot_ac": "G3MZR3", "uniprot_id": "G3MZR3_BOVIN", "mass": { "chemical_mass": 121806.0, "monoisotopic_mass": 121806.0 }, "refseq": { "ac": "XP_024853824", "name": "selenocysteine insertion sequence-binding protein 2-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853824" }, "gene_names": [ { "name": "SECISBP2L", "type": "recommended", "evidence": [ { "id": "G3MZR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZR3" } ] }, { "name": "SECISBP2L", "type": "synonym", "evidence": [ { "id": "XP_024853824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853824" } ] } ], "protein_names": [ { "name": "SECIS binding protein 2 like", "type": "synonym", "evidence": [ { "id": "G3MZR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZR3/entry#names_and_taxonomy" } ] }, { "name": "selenocysteine insertion sequence-binding protein 2-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024853824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853824" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZR3", "url": "https://www.uniprot.org/uniprotkb/G3MZR3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SECISBP2L", "url": "https://www.uniprot.org/uniprotkb/G3MZR3", "locus": { "chromosome": "10", "start_pos": 61240553, "end_pos": 61182254, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046553", "url": "https://www.ensembl.org/id/ENSBTAG00000046553" } ] } } ], "crossref": [ { "id": "G3MZR3", "url": "https://alphafold.ebi.ac.uk/entry/G3MZR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046553", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046553", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100848979", "url": "https://www.ncbi.nlm.nih.gov/gene/100848979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100848979", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848979", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYHSGCQ", "url": "https://omabrowser.org/oma/group/DYHSGCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZR3", "url": "https://www.orthodb.org/?gene=G3MZR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13284", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13284", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13284:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13284:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024853824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853824", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S9J4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9J4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZR3", "url": "https://www.uniprot.org/uniprotkb/G3MZR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZR3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRAPADQNVKLSAEVEPFIPQKKNPDTFMIPMALPNDNGNVSGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPAGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPAPYSNTFQAANTVNTITTECTERPNHLGQVFPLSGHRNRNSNRGPVVPKQQLTQQHIKSKRPLVKNVAIQKETSAAGPDNRSKIVLLVDASQQTDFPSDIANKSLSESSAAMLWKAKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSTSQQPAAGGSRNPDAGSVSHVDSSICAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQVGFRCRGHSTSSERRQNLQKRQDNKQLNPSQSHRGDPNSESLYFEDQDGFRELSENGNAKDENMQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSFNSLDITSSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVDHNLLGSEEPVEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLETSENEREVSCKHSTSEKPNKLPFDTAPVGKQASLVTAGSTTSATNPGKSAVGDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEDDEEEEEEEDYAHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNAEQSGEEEAEAAEVLEPGMDSEAWTTDHQASQEQQKPSNCSSLNKEHSDSNYTPPDL", "length": 1102, "header": "tr|G3MZR3-1|G3MZR3_BOVIN Isoform 1 of SECIS binding protein 2 like OS=Bos taurus OX=9913 GN=SECISBP2L PE=4 SV=2 CANONICAL=G3MZR3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S9J4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9J4/entry", "sequence": { "sequence": "MDRAPADQNVKLSAEVEPFIPQKKNPDTFMIPMALPNDNGNVSGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPAGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPAPYSNTFQAANTVNTITTECTERPNHLGQVFPLSGHRNRNSNRGPVVPKQQLTQQHIKSKRPLVKNVAIQKETSAAGPDNRSKIVLLVDASQQTDFPSDIANKSLSESSAAMLWKAKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSTSQQPAAGGSRNPDAGSVSHVDSSICAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQVGFRCRGHSTSSERRQNLQKRQDNKQLNPSQSHRGDPNSESLYFEDQDGFRELSENGNAKDENMQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTDTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLETSENEREVSCKHSTSEKPNKLPFDTAPVGKQASLVTAGSTTSATNPGKSAVGDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEDDEEEEEEEDYAHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNAEQSGEEEAEAAEVLEPGMDSEAWTTDHQASQEQQKPSNCSSLNKEHSDSNYTPPDL", "length": 1001, "header": "tr|A0AAA9S9J4-1|G3MZR3_BOVIN Computationally mapped isoform of SECIS binding protein 2 like OS=Bos taurus OX=9913 GN=SECISBP2L PE=4 SV=1 CANONICAL=G3MZR3-1" }, "locus": { "chromosome": "10", "start_pos": 61239549, "end_pos": 61182508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120973.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120973.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081955.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081955.1" } ] } }, { "isoform_ac": "A0AAA9TFY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFY8/entry", "sequence": { "sequence": "MDRAPADQNVKLSAEVEPFIPQKKNPDTFMIPMALPNDNGNVSGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPAGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPAPYSNTFQAANTVNTITTECTERPNHLGQVFPLSGHRNRNSNRGPVVPKQQLTQQHIKSKRPLVKNVAIQKETSAAGPDNRSKIVLLVDASQQTDFPSDIANKSLSESSAAMLWKAKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSTSQQPAAGGSRNPDAGSVSHVDSSICAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQDQDGFRELSENGNAKDENMQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSFNSLDITSSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVDHNLLGSEEPVEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLETSENEREVSCKHSTSEKPNKLPFDTAPVGKQASLVTAGSTTSATNPGKSAVGDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEDDEEEEEEEDYAHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNAEQSGEEEAEAAEVLEPGMDSEAWTTDHQASQEQQKPSNCSSLNKEHSDSNYTPPDL", "length": 1057, "header": "tr|A0AAA9TFY8-1|G3MZR3_BOVIN Computationally mapped isoform of SECIS binding protein 2 like OS=Bos taurus OX=9913 GN=SECISBP2L PE=4 SV=1 CANONICAL=G3MZR3-1" }, "locus": { "chromosome": "10", "start_pos": 61239549, "end_pos": 61182508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088405.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088405.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097085.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097085.1" } ] } }, { "isoform_ac": "G3MZR3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZR3/entry", "sequence": { "sequence": "MDRAPADQNVKLSAEVEPFIPQKKNPDTFMIPMALPNDNGNVSGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPNPNPAGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPAPYSNTFQAANTVNTITTECTERPNHLGQVFPLSGHRNRNSNRGPVVPKQQLTQQHIKSKRPLVKNVAIQKETSAAGPDNRSKIVLLVDASQQTDFPSDIANKSLSESSAAMLWKAKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSTSQQPAAGGSRNPDAGSVSHVDSSICAGGVNWSNVTCQATQKKPWMEKNQTFSRGGRQTEQRNNSQVGFRCRGHSTSSERRQNLQKRQDNKQLNPSQSHRGDPNSESLYFEDQDGFRELSENGNAKDENMQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLSYTVVTAASFHTKDSTNRKPLTKSQPCLTSFNSLDITSSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVDHNLLGSEEPVEMHLDFIDDLPQEIVSQEDTGLSMPSDTSLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLCKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNKLVELTEEARKAYKDMVAAMEQEQAEEALKNVKKVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRNMVETSDGLETSENEREVSCKHSTSEKPNKLPFDTAPVGKQASLVTAGSTTSATNPGKSAVGDKEEVKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEDDEEEEEEEDYAHEPISVEVQLNSRIESWVSETQRTMETLQLGKTLNGSEEDNAEQSGEEEAEAAEVLEPGMDSEAWTTDHQASQEQQKPSNCSSLNKEHSDSNYTPPDL", "length": 1102, "header": "tr|G3MZR3-1|G3MZR3_BOVIN Isoform 1 of SECIS binding protein 2 like OS=Bos taurus OX=9913 GN=SECISBP2L PE=4 SV=2 CANONICAL=G3MZR3-1" }, "locus": { "chromosome": "10", "start_pos": 61239549, "end_pos": 61182508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065830.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065830.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055066.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055066.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100848979", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848979", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GIQ2-1", "protein_name": "SECIS binding protein 2-like", "gene_name": "Secisbp2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EERCPGNVKLSAEVEPFIPQKKNLDAFVLPMALPTDNGSVSGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPSPSPTGPYLAYPILSAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPTPYSSTFQAANTVNAITTECTERPNQLGQPFPLSSHRSRNGNRGPVVPKPQLLQQHIKNKRPQVKNVATQKETSAAGPDSRSKIVLLVDASQQTDFPSDIANKSLSESTATMLWKGKGRRRRASHPAAESSSEQGASEADIDSDSGYCSPKHNNQPAPGTLRDPASGTISHSESSGCTGGVNWPKVTCQATQKRPWMEKNQAFSRGGRQTEQRNNSQVGFRCRGHSTSSERRQNLQKRQDNKHLNSTQSHRSDPNSESLYFEDEDGFQELSESGNSKDETIQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISMEQKKLQEALSKAAGKKNKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLAHPVVTTGTFHTKDSNRKTLTRSQPCLTSFNSLDITSSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLTVEHSVLGAEELTETNLDLANDLPQETISQEDTGLSMPSDASLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLSKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNRLVELTEEARKAYKDMVAATEQEQAEEALRSVKAVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRSMVETSDGLETSESEKAVPCKHDPAEKPSKLTPDTTQVGKQPLPPTGSITSAPSQGKPTVDKDELKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEDDEEEEEEDYIHEPTSEEVQLNSRIESWVSETQRTMETLQLGKALPGSEEDSAEQSGEEAVEMAEGLESVVDSETWTPDQQPKPSRNVSKEHPDFSSPPPST", "length": 1087 }, "evidence": [ { "id": "G3MZR3", "url": "https://omabrowser.org/oma/group/G3MZR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6A098-1", "protein_name": "Selenocysteine insertion sequence-binding protein 2-like", "gene_name": "Secisbp2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRAPAEQNVKLSAEVEPFVPQKKNLDAFVLPMALPSDNGSVSGVEPTPIPSYLITCYPFVQENQSNRQFPLYNNDIRWQQPSPSPTGPYLAYPIISAQPPVSTEYTYYQLMPAPCAQVMGFYHPFPTPYSSTFQAANTVNAISTECTERPNQLGQAFPLSSHRSRNGNRGPVVPKPQLLQQHIKNKRPQVKNVATQKETSATGPDSRSKIVLLVDASQQTDFPSDIANKSLSESTATMLWKAKGRRRRASHPAVESSSEQGASEADIDSDSGYCSPKHNNQSAPGALRDPASGTMNRLESSGCSGGVNWPKVTCQATQKRPWMEKNQAFSRGGRQTEQRNNLQVGFRCRGHSTSSERRQNLQKRQDNKHLNSTQSHRSDPNSESLYFEDEDGFQELSENGNSKDENIQQKLSSKVLDDLPENSPINIVQTPIPITTSVPKRAKSQKKKALAAALATAQEYSEISKKSCRKLYQKQLEKTKTPVQLDLGDMLAALEKQQQAMKARQITNTRPLAHPVVTTATFHTKDSNRKTLAKSQPCVTSFNSLDITSSKAKKGKEKEIAKLKRPTALKKVILKEREEKKGRLIVEHSVLGAEEPTETHLDLTNDLPQETVSQEDAGLSMPSDASLSPASQNSPYCMTPVSQGSPASSGIGSPMASSTITKIHSKRFREYCNQVLSKEIDECVTLLLQELVSFQERIYQKDPVRAKARRRLVMGLREVTKHMKLNKIKCVIISPNCEKIQSKGGLDEALYNVIAMAREQEIPFVFALGRKALGRCVNKLVPVSVVGIFNYFGAESLFNRLVELTEEARKAYKDMVAATEQEQAEEALRSVKTVPHHMGHSRNPSAASAISFCSVISEPISEVNEKEYETNWRSMVETSDGLEPSEMEKAAPCTHSPPEKPSRLALDTSLVGKQLPLAAGSITSAPSQGKPTGDKDELKPDDLEWASQQSTETGSLDGSCRDLLNSSITSTTSTLVPGMLEEEEDEEEEEEDYSHEPTAEEVQLNSRIESWVSETQRTMETLQLGKALPGSEEDSAEQSGEEAAEVPEGLESGADSETWTPDQPPKPSSNMGKEHPDSSSPPQST", 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"categories": [ "Protein Classification" ] }, { "id": "PTHR13999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13999:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13999:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SBF7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E542", "url": 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transmembrane protein 1 OS=Bos taurus OX=9913 GN=LOC112444847 PE=3 SV=1 CANONICAL=G5E542-1" }, "locus": { "chromosome": "29", "start_pos": 51005822, "end_pos": 51003942, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106666.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106666.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079536.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079536.1" } ] } }, { "isoform_ac": "G5E542-1", "url": "https://www.uniprot.org/uniprotkb/G5E542/entry", "sequence": { "sequence": "MIKEEHEVAVLGAPQSQAPLTTTVINIRSDTAVPDHIVWSLFNTIFLNWCCLGFVAFAYSVKPHQGRRSLHTQLQNTSLVRKRGRCCKDPDPWCSRDRKMVGDITGAQSYASTAKCLNIWALVLGIFLTIGSIVLLIFVYMAAYETALRISRHGGH", "length": 156, "header": "tr|G5E542-1|G5E542_BOVIN Isoform 1 of Interferon-induced transmembrane protein 1 OS=Bos taurus OX=9913 GN=LOC112444847 PE=3 SV=3 CANONICAL=G5E542-1" }, "locus": { "chromosome": "29", "start_pos": 51004894, "end_pos": 51003942, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004215.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004215.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004215.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004215.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E542", "url": "https://www.uniprot.org/uniprotkb/G5E542" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": 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{ "name": "response to type II interferon", "id": "GO:0034341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034341", "evidence": [ { "database": "UniProtKB", "id": "G5E542", "url": "https://www.uniprot.org/uniprotkb/G5E542" } ], "pmid": "" }, { "name": "response to interferon-alpha", "id": "GO:0035455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035455", "evidence": [ { "database": "UniProtKB", "id": "G5E542", "url": "https://www.uniprot.org/uniprotkb/G5E542" } ], "pmid": "" }, { "name": "response to interferon-beta", "id": "GO:0035456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035456", "evidence": [ { "database": "UniProtKB", "id": "G5E542", "url": "https://www.uniprot.org/uniprotkb/G5E542" } ], "pmid": "" }, { "name": "host-mediated suppression of symbiont invasion", "id": "GO:0046597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046597", "evidence": [ { "database": "UniProtKB", "id": "G5E542", "url": "https://www.uniprot.org/uniprotkb/G5E542" } ], "pmid": "" } ] } ] 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OS=Bos taurus OX=9913 GN=EML3 PE=3 SV=1 CANONICAL=F6RJ80-1" }, "locus": { "chromosome": "29", "start_pos": 40957006, "end_pos": 40948769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125284.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125284.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081230.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081230.1" } ] } }, { "isoform_ac": "F6RJ80-1", "url": "https://www.uniprot.org/uniprotkb/F6RJ80/entry", "sequence": { "sequence": "MTPPSPSSAVCRYRRPRSTRVCGGKQEARGEGPAQEALQSLSRRLQVQEKEMELVKAALAEALRLLRLQAPSTSLQDPGTLGPPRDSPAAPPGLPPTCSPSLVSRGTQTEAEMEVEPSPGPPGLSNGPPAPPGGSEEPSGTQSEGGGSSSSGTGSPGPPGILRLAQPPQRTDTPRRNSSSSSPSERPRQKLSRKAASSANLLLRSGSTESRGGKDPLSSPGGPGSRRSNYNLEGISVKMFLRGRPITMYIPSGIRSLEELPSGPPPETLSLDWVYGYRGRDSRSNLFVLRSGEVVYFIACVVVLYRPGGGPGGPGGGGQRHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHVWDSETLLKLQEIGLGAFERGVGALAFSVVDQGAFLCVVDDSNEHMLSVWDCSRGTKLAEIKSTNDSVLAVGFNPRDSSSIVTSGKSHVHFWNWNGGTGVPGNGTLTRKQGVFGKYKKPKFIPCFVFLPDGDILTGDSEGNILTWGRSLSDSRTPGRGGAKETYGIVAQAHAHEGSIFALCLRRDGTVLSGGGRDRRLVQWGPGLVALQEAEIPEHFGAVRAIAEGPGSELLVGTTKNALLRGDLAQGFSPVIQGHTDELWGLCTHPFQNRFLTCGHDRQLCLWDGEGHALAWSIDLKETGLCADFHPSGAVVAVGLNTGRWLVLDTETREIVSDITDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSDGAKSSRFGRCVGHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKLLRNRYESRDREWATYTCVLGFHVYGVWPDGSDGTDINSLCRSHNERVVAVADDFCKVHLFQYPCAHAKAPSLVYGGHGSHVTSVRFTHDDSHLISLGGKDASIFQWRVLGAGGTGPVPTTPSRTPSLSPASSLDV", "length": 917, "header": "tr|F6RJ80-1|F6RJ80_BOVIN Isoform 1 of Echinoderm microtubule-associated protein-like 3 OS=Bos taurus OX=9913 GN=EML3 PE=3 SV=2 CANONICAL=F6RJ80-1" }, "locus": { "chromosome": "29", "start_pos": 40959207, "end_pos": 40948281, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015756.6", "url": "https://www.ensembl.org/id/ENSBTAT00000015756.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015756.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015756.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F6RJ80", "url": "https://www.uniprot.org/uniprotkb/F6RJ80" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": 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"UniProtKB", "id": "F6RJ80", "url": "https://www.uniprot.org/uniprotkb/F6RJ80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F6RJ80", "url": "https://www.uniprot.org/uniprotkb/F6RJ80" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "F6RJ80", "url": "https://www.uniprot.org/uniprotkb/F6RJ80" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "F6RJ80", "url": "https://www.uniprot.org/uniprotkb/F6RJ80" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": 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"1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RJ80-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RJ80" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ80" }, { "id": "PF23409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like first beta-propeller", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 604, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RJ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ80" }, { "id": "PF23414", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like second beta-propeller", 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"MASRERLFELWMLYCSKKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDVPPGISLLPDNILQVLRIQLLQCVQKMADGLEEEQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKELADQTSIEEFVIHALAFCESLYDPYRNWRQRISGRIFSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQKNALQAISPATMEVLMRVLADCDSWEDGNPEEVGRKVELTLKCLTEVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKLFLNANSKVADKNEKDLANKLLTEMNEDQVFQGQLDYLAVSAIQALTAVMNKSPAAKEVFKERIGYTHMFEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELESHDLQVFISDWLKKICCINRQSRTTCVNANMGIRIIEALNSHSCLHRTCAENLIALHGSLGSQSVSSEEIRQLLRLLRVDESESVHPYTTPVTRAILTMARKQSLESALQYFNLSHSMAGISVPSIQKWPGSAFSFNAWFCLDQDQLTLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFISCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTTEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEALQPPQVKALYLAGPNCLSPWKFQESDMADLPGNVLLHYTAKACKNAICLDLSTNCFHGRLTGNKVVNWDIKDVINCIGGLNVLFPLLEQISHFGEGQIPEGLNESTVSELITPVEGDWVVLTSTKASESRLERNLIATFILIVKHFIQRHPINQDNLIHSHGVAVLGALLQKVPSALMDVNVLMAIQLLIEQVSLEKNMQLLQQMYQYLLFDFHIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNDCKYNELSPDDIRTIRTSLYGLIKYFLSKGGTHEEIQSIMGYIAAINEEEQLLGILDILFSLLRTSPNRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVGYSGFGLLLNEAPVNTSLIKSLTNQIINTDPAINFKDLLSVVYISHRAYINVRVVICRKMLQILQSQPDAAHQISQQVGWQDTLVKLFLKANFENGNTLHKHNRAIIVKDNDKNISVEDMKRSFDEKTDEEKIASFASAHVSSDEWSLEDRHSLDSNMPLFQEDSSMGELSFKSENQEEFWHNNPSPLSLDLSGIDSCELSDGGSQMPDSLPSTPSPVESMKPFPVQPDKESSVTNDVGFSDDFSLLENKERCEEELIQLLTNILSCIMCKGLEKSDDDTWIERGQVFSALTKPGISSELLRPSDEIKLVLLQKMLEWAVTENREAKMNPVTAENAFRLTLIIQDFLQSEGLVNSNMWTEKLLEDLMLLFDSLSVWYSESPVGVKLSQIQIQLLLGFIGKGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPLTNGSASFFEDFQEYCSSNEWQVYIEKYIVPYMKKYETHTFYDSHESMALYWKDCYEALMVNMHKRDRDGGESKLKFQEFFVEPFNRKVRQENLRYNNMLKQLSSQQLATLRRWKAVKLYLTCERGPWAKRQQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDSLLLEVVKQVKVSDMEEDKLDLPEEEITSRVNIDEKEEQNQKEKLVLSEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQVREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNSYGTRSPQELFKASGLTQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPSVFRDLSKPIGVVNDKNAKATREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRTEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQSNLGRLQVSKELVNDVVLPKWAKSAEDFICKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPSRLSAEEAVQKQAKTDTSTFNLFQHLPELKSFFIEGISDGIPLVKAIVPKNQSRSFMSQGSPELLITLSMNHIIGTHGWLPYDRNISNYFTFIRDQTVTNPKTQRSMNGPFAPGLEITSKLFIVSHDAKLLFSAGHWDNSIQVMSLTKGKLISHNIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPMGLASKPFQILYGHTDEVLSVAISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLLLTIPNLAISWEGHIVMYSSIEESTSLKDKNALHLFSVNGKYLGSQVLKEQVSDICIIGEHIVTGSLQGFLSIRDLHSLNLCISPLAMRSPIHCVCVTKEYSHILVGLEDGKLIVVGVGRPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDSK", "length": 2722, "header": "tr|G3N3Y1-1|G3N3Y1_BOVIN Isoform 1 of Neurobeachin like 1 OS=Bos taurus OX=9913 GN=NBEAL1 PE=4 SV=4 CANONICAL=G3N3Y1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEF0/entry", "sequence": { "sequence": "MASRERLFELWMLYCSKKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDVPPGISLLPDNILQVLRIQLLQCVQKMADGLEEEQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKELADQTSIEEFVIHALAFCESLYDPYRNWRQRISGRIFSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQKNALQAISPATMEVLMRVLADCDSWEDGNPEEVGRKVELTLKCLTEVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKLFLNANSKVADKNEKDLANKLLTEMNEDQVFQGQLDYLAVSAIQALTAVMNKSPAAKEVFKERIGYTHMFEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELESHDLQVFISDWLKKICCINRQSRTTCVNANMGIRIIEALNSHSCLHRTCAENLIALHGSLGSQSVSSEEIRQLLRLLRVDESESVHPYTTPVTRAILTMARKQSLESALQYFNLSHSMAGISVPSIQKWPGSAFSFNAWFCLDQDQLTLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFISCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTTEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEALQPPQVKALYLAGPNCLSPWKFQESDMADLPGNVLLHYTAKACKNAICLDLSTNCFHGRLTGNKVVNWDIKDVINCIGGLNVLFPLLEQISHFGEGQIPEGLNESTVSELITPVEGDWVVLTSTKASESRLERNLIATFILIVKHFIQRHPINQDNLIHSHGVAVLGALLQKVPSALMDVNVLMAIQLLIEQVSLEKNMQLLQQMYQYLLFDFHIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNDCKYNELSPDDIRTIRTSLYGLIKYFLSKGGTHEEIQSIMGYIAAINEEEQLLGILDILFSLLRTSPNRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVGYSGFGLLLNEAPVNTSLIKSLTNQIINTDPAINFKDLLSVVYISHRAYINVRVVICRKMLQILQSQPDAAHQISQQVGWQDTLVKLFLKANFENGNTLHKHNRAIIVKDNDKNISVEDMKRSFDEKTDEEKIASFASAHVSSDEWSLEDRHSLDSNMPLFQEDSSMGELSFKSENQEEFWHNNPSPLSLDLSGIDSCELSDGGSQMPDSLPSTPSPVESMKPFPVQPDKESSVTNDVGFSDDFSLLENKERCEEELIQLLTNILSCIMCKGLEKSDDDTWIERGQVFSALTKPGISSELLRPSDEIKLVLLQKMLEWAVTENREAKMNPVTAENAFRLTLIIQDFLQSEGLVNSNMWTEKLLEDLMLLFDSLSVWYSESPVGVKLSQIQIQLLLGFIGKGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPLTNGSASFFEDFQEYCSSNEWQVYIEKYIVPYMKKYETHTFYDSHESMALYWKDCYEALMVNMHKRDRDGGESKLKFQEFFVEPFNRKVRQENLRYNNMLKQLSSQQLATLRRWKAVKLYLTCERGPWAKRQQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDSLLLEVVKQVKVSDMEEDKLDLPEEEITSRVNIDEKEEQNQKEKLVLSEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQVREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNSYGTRSPQELFKASGLTQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPSVFRDLSKPIGVVNDKNAKATREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRTEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQVSKELVNDVVLPKWAKSAEDFICKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPSRLSAEEAVQKQAKTDTSTFNLFQHLPELKSFFIEGISDGIPLVKAIVPKNQSRSFMSQGSPELLITLSMNHIIGTHGWLPYDRNISNYFTFIRDQTVTNPKTQRSMNGPFAPGLEITSKLFIVSHDAKLLFSAGHWDNSIQVMSLTKGKLISHNIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPMGLASKPFQILYGHTDEVLSVAISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLLLTIPNLAISWEGHIVMYSSIEESTSLKDKNALHLFSVNGKYLGSQVLKEQVSDICIIGEHIVTGSLQGFLSIRDLHSLNLCISPLAMRSPIHCVCVTKEYSHILVGLEDGKLIVVGVGRPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDSK", "length": 2722, "header": "tr|A0AAA9SEF0-1|G3N3Y1_BOVIN Computationally mapped isoform of Neurobeachin like 1 OS=Bos taurus OX=9913 GN=NBEAL1 PE=4 SV=2 CANONICAL=G3N3Y1-1" }, "locus": { "chromosome": "2", "start_pos": 91471374, "end_pos": 91318319, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118504.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118504.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083775.2", "url": "https://www.ensembl.org/id/ENSBTAP00000083775.2" } ] } }, { "isoform_ac": "A0AAA9SH91-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH91/entry", "sequence": { "sequence": "MIFLFQKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDVPPGISLLPDNILQVLRIQLLQCVQKMADGLEEEQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKELADQTSIEEFVIHALAFCESLYDPYRNWRQRISGRIFSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQKNALQAISPATMEVLMRVLADCDSWEDGNPEEVGRKVELTLKCLTEVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDYLAVSAIQALTAVMNKSPAAKEVFKERIGYTHMFEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELESHDLQVFISDWLKKICCINRQSRTTCVNANMGIRIIEALNSHSCLHRTCAENLIALHGSLGSQSVSSEEIRQLLRLLRVDESESVHPYTTPVTRAILTMARKQSLESALQYFNLSHSMAGISVPSIQKWPGSAFSFNAWFCLDQDQLTLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFISCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTTEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEALQPPQVKALYLAGPNCLSPWKFQESDMADLPGNVLLHYTAKACKNAICLDLSTNCFHGRLTGNKVVNWDIKDVINCIGGLNVLFPLLEQISHFGEGQIPEGLNESTVSELITPVEGDWVVLTSTKASESRLERNLIATFILIVKHFIQRHPINQDNLIHSHGVAVLGALLQKVPSALMDVNVLMAIQLLIEQVSLEKNMQLLQQMYQYLLFDFHIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNDCKYNELSPDDIRTIRTSLYGLIKYFLSKGGTHEEIQSIMGYIAAINEEEQLLGILDILFSLLRTSPNRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVGYSGFGLLLNEAPVNTSLIKSLTNQIINTDPAINFKDLLSVVYISHRAYINVRVVICRKMLQILQSQPDAAHQISQQVGWQDTLVKLFLKANFENGNTLHKHNRAIIVKDNDKNISVEDMKRSFDEKTDEEKIASFASAHVSSDEWSLEDRHSLDSNMPLFQEDSSMGELSFKSENQEEFWHNNPSPLSLDLSGIDSCELSDGGSQMPDSLPSTPSPVESMKPFPVQPDKESSVTNDVGFSDDFSLLENKERCEEELIQLLTNILSCIMCKGLEKSDDDTWIERGQVFSALTKPGISSELLRPSDEIKLVLLQKMLEWAVTENREAKMNPVTAENAFRLTLIIQDFLQSEGLVNSNMWTEKLLEDLMLLFDSLSVWYSESPVGVKLSQIQIQLLLGFIGKGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPLTNGSASFFEDFQEYCSSNEWQVYIEKYIVPYMKKYETHTFYDSHESMALYWKDCYEALMVNMHKRDRDGGESKLKFQEFFVEPFNRKVRQENLRYNNMLKQLSSQQLATLRRWKAVKLYLTCERGPWAKRQQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDSLLLEVVKQVKVSDMEEDKLDLPEEEITSRVNIDEKEEQNQKEKLVLSEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQVREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNSYGTRSPQELFKASGLTQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPSVFRDLSKPIGVVNDKNAKATREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRTEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQVSKELVNDVVLPKWAKSAEDFICKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKITLSMNHIIGTHGWLPYDRNISNYFTFIRDQTVTNPKTQRSMNGPFAPGLEITSKLFIVSHDAKLLFSAGHWDNSIQVMSLTKGKLISHNIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPMGLASKPFQILYGHTDEVLSVAISTELDMAVSGSRDGTVIIHTIPNLAISWEGHIVMYSSIEESTSLKDKNALHLFSVNGKYLGSQVLKEQVSDICIIGEHIVTGSLQGFLSIRDLHSLNLCISPLAMRSPIHCVCVTKEYSHILVGLEDGKLIVVGVGRPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDSK", "length": 2592, "header": "tr|A0AAA9SH91-1|G3N3Y1_BOVIN Computationally mapped isoform of Neurobeachin like 1 OS=Bos taurus OX=9913 GN=NBEAL1 PE=4 SV=2 CANONICAL=G3N3Y1-1" }, "locus": { "chromosome": "2", "start_pos": 91471374, "end_pos": 91338906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135564.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135564.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084703.2", "url": "https://www.ensembl.org/id/ENSBTAP00000084703.2" } ] } }, { "isoform_ac": "A0AAA9SMR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMR4/entry", "sequence": { "sequence": "MASRERLFELWMLYCSKKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDVPPGISLLPDNILQVLRIQLLQCVQKMADGLEEEQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKELADQTSIEEFVIHALAFCESLYDPYRNWRQRISGRIFSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQKNALQAISPATMEVLMRVLADCDSWEDGNPEEVGRKVELTLKCLTEVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDYLAVSAIQALTAVMNKSPAAKEVFKERIGYTHMFEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELESHDLQVFISDWLKKICCINRQSRTTCVNANMGIRIIEALNSHSCLHRTCAENLIALHGSLGSQSVSSEEIRQLLRLLRVDESESVHPYTTPVTRAILTMARKQSLESALQYFNLSHSMAGISVPSIQKWPGSAFSFNAWFCLDQDQLTLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFISCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTTEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEALQPPQVKALYLAGPNCLSPWKFQESDMADLPGNVLLHYTAKACKNAICLDLSTNCFHGRLTGNKVVNWDIKDVINCIGGLNVLFPLLEQISHFGEGQIPEGLNESTVSELITPVEGDWVVLTSTKASESRLERNLIATFILIVKHFIQRHPINQDNLIHSHGVAVLGALLQKVPSALMDVNVLMAIQLLIEQVSLEKNMQLLQQMYQYLLFDFHIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNDCKYNELSPDDIRTIRTSLYGLIKYFLSKGGTHEEIQSIMGYIAAINEEEQLLGILDILFSLLRTSPNRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVGYSGFGLLLNEAPVNTSLIKSLTNQIINTDPAINFKDLLSVVYISHRAYINVRVVICRKMLQILQSQPDAAHQISQQVGWQDTLVKLFLKANFENGNTLHKHNRAIIVKDNDKNISVEDMKRSFDEKTDEEKIASFASAHVSSDEWSLEDRHSLDSNMPLFQEDSSMGELSFKSENQEEFWHNNPSPLSLDLSGIDSCELSDGGSQMPDSLPSTPSPVESMKPFPVQPDKESSVTNDVGFSDDFSLLENKERCEEELIQLLTNILSCIMCKGLEKSDDDTWIERGQVFSALTKPGISSELLRPSDEIKLVLLQKMLEWAVTENREAKMNPVTAENAFRLTLIIQDFLQSEGLVNSNMWTEKLLEDLMLLFDSLSVWYSESPVGVKLSQIQIQLLLGFIGKGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPLTNGSASFFEDFQEYCSSNEWQVYIEKYIVPYMKKYETHTFYDSHESMALYWKDCYEALMVNMHKRDRDGGESKLKFQEFFVEPFNRKVRQENLRYNNMLKQLSSQQLATLRRWKAVKLYLTCERGPWAKRQQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDSLLLEVVKQVKVSDMEEDKLDLPEEEITSRVNIDEKEEQNQKEKLVLSEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQVREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNSYGTRSPQELFKASGLTQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPSVFRDLSKPIGVVNDKNAKATREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRTEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQSNLGRLQVSKELVNDVVLPKWAKSAEDFICKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKGISDGIPLVKAIVPKNQSRSFMSQGSPELLITLSMNHIIGTHGWLPYDRNISNYFTFIRDQTVTNPKTQRSMNGPFAPGLEITSKLFIVSHDAKLLFSAGHWDNSIQVMSLTKGKLISHNIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPMGLASKPFQILYGHTDEVLSVAISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLLLTIPNLAISWEGHIVMYSSIEESTSLKDKNALHLFSVNGKYLGSQVLKEQVSDICIIGEHIVTGSLQGFLSIRDLHSLNLCISPLAMRSPIHCVCVTKEYSHILVGLEDGKLIVVGVGRPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDSK", "length": 2654, "header": "tr|A0AAA9SMR4-1|G3N3Y1_BOVIN Computationally mapped isoform of Neurobeachin like 1 OS=Bos taurus OX=9913 GN=NBEAL1 PE=4 SV=1 CANONICAL=G3N3Y1-1" }, "locus": { "chromosome": "2", "start_pos": 91471374, "end_pos": 91318319, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114447.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114447.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085176.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085176.1" } ] } }, { "isoform_ac": "A0AAA9SS63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS63/entry", "sequence": { "sequence": "MHWHFAKVYMIHIGIGGNEFQECFQESEHLKESLKCCLLHLFGAIVAGGQKNALQAISPATMEVLMRVLADCDSWEDGNPEEVGRKVELTLKCLTEVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDYLAVSAIQALTAVMNKSPAAKEVFKERIGYTHMFEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELESHDLQVFISDWLKKICCINRQSRTTCVNANMGIRIIEALNSHSCLHRTCAENLIALHGSLGSQSVSSEEIRQLLRLLRVDESESVHPYTTPVTRAILTMARKQSLESALQYFNLSHSMAGISVPSIQKWPGSAFSFNAWFCLDQDQLTLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFISCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTTEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEALQPPQVKALYLAGPNCLSPWKFQESDMADLPGNVLLHYTAKACKNAICLDLSTNCFHGRLTGNKVVNWDIKDVINCIGGLNVLFPLLEQISHFGEGQIPEGLNESTVSELITPVEGDWVVLTSTKASESRLERNLIATFILIVKHFIQRHPINQDNLIHSHGVAVLGALLQKVPSALMDVNVLMAIQLLIEQVSLEKNMQLLQQMYQYLLFDFHIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNDCKYNELSPDDIRTIRTSLYGLIKYFLSKGGTHEEIQSIMGYIAAINEEEQLLGILDILFSLLRTSPNRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVGYSGFGLLLNEAPVNTSLIKSLTNQIINTDPAINFKDLLSVVYISHRAYINVRVVICRKMLQILQSQPDAAHQISQQVGWQDTLVKLFLKANFENGNTLHKHNRAIIVKDNDKNISVEDMKRSFDEKTDEEKIASFASAHVSSDEWSLEDRHSLDSNMPLFQEDSSMGELSFKSENQEEFWHNNPSPLSLDLSGIDSCELSDGGSQMPDSLPSTPSPVESMKPFPVQPDKESSVTNDVGFSDDFSLLENKERCEEELIQLLTNILSCIMCKGLEKSDDDTWIERGQVFSALTKPGISSELLRPSDEIKLVLLQKMLEWAVTENREAKMNPVTAENAFRLTLIIQDFLQSEGLVNSNMWTEKLLEDLMLLFDSLSVWYSESPVGVKLSQIQIQLLLGFIGKGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPLTNGSASFFEDFQEYCSSNEWQVYIEKYIVPYMKKYETHTFYDSHESMALYWKDCYEALMVNMHKRDRDGGESKLKFQEFFVEPFNRKVRQENLRYNNMLKQLSSQQLATLRRWKAVKLYLTCERGPWAKRQQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDSLLLEVVKQVKVSDMEEDKLDLPEEEITSRVNIDEKEEQNQKEKLVLSEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQVREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNSYGTRSPQELFKASGLTQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPSVFRDLSKPIGVVNDKNAKATREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRTEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQVSKELVNDVVLPKWAKSAEDFICKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPSRLSAEEAVQKQAKTDTSTFNLFQHLPELKSFFIEGISDGIPLVKAIVPKNQSRSFMSQGSPELLITLSMNHIIGTHGWLPYDRNISNYFTFIRDQTVTNPKTQRSMNGPFAPGLEITSKLFIVSHDAKLLFSAGHWDNSIQVMSLTKGKLISHNIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPMGLASKPFQILYGHTDEVLSVAISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLLLTIPNLAISWEGHIVMYSSIEESTSLKDKNALHLFSVNGKYLGSQVLKEQVSDICIIGEHIVTGSLQGFLSIRDLHSLNLCISPLAMRSPIHCVCVTKEYSHILVGLEDGKLIVVGVGRPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDSK", "length": 2515, "header": "tr|A0AAA9SS63-1|G3N3Y1_BOVIN Computationally mapped isoform of Neurobeachin like 1 OS=Bos taurus OX=9913 GN=NBEAL1 PE=4 SV=2 CANONICAL=G3N3Y1-1" }, "locus": { "chromosome": "2", "start_pos": 91471374, "end_pos": 91354418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112484.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112484.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088176.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088176.2" } ] } }, { "isoform_ac": "A0ABI0P202-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P202/entry", "sequence": { "sequence": "MASRERLFELWMLYCSKKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDVPPGISLLPDNILQVLRIQLLQCVQKMADGLEEEQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKELADQTSIEEFVIHALAFCESLYDPYRNWRQRISGRIFSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQKNALQAISPATMEVLMRVLADCDSWEDGNPEEVGRKVELTLKCLTEVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDYLAVSAIQALTAVMNKSPAAKEVFKERIGYTHMFEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELESHDLQVFISDWLKKICCINRQSRTTCVNANMGIRIIEALNSHSCLHRTCAENLIALHGSLGSQSVSSEEIRQLLRLLRVDESESVHPYTTPVTRAILTMARKQSLESALQYFNLSHSMAGISVPSIQKWPGSAFSFNAWFCLDQDQLTLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFISCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTTEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEALQPPQVKALYLAGPNCLSPWKFQESDMADLPGNVLLHYTAKACKNAICLDLSTNCFHGRLTGNKVVNWDIKDVINCIGGLNVLFPLLEQISHFGEGQIPEGLNESTVSELITPVEGDWVVLTSTKASESRLERNLIATFILIVKHFIQRHPINQDNLIHSHGVAVLGALLQKVPSALMDVNVLMAIQLLIEQVSLEKNMQLLQQMYQYLLFDFHIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNDCKYNELSPDDIRTIRTSLYGLIKYFLSKGGTHEEIQSIMGYIAAINEEEQLLGILDILFSLLRTSPNRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVGYSGFGLLLNEAPVNTSLIKSLTNQIINTDPAINFKDLLSVVYISHRAYINVRVVICRKMLQILQSQPDAAHQISQQVGWQDTLVKLFLKANFENGNTLHKHNRAIIVKDNDKNISVEDMKRSFDEKTDEEKIASFASAHVSSDEWSLEDRHSLDSNMPLFQEDSSMGELSFKSENQEEFWHNNPSPLSLDLSGIDSCELSDGGSQMPDSLPSTPSPVESMKPFPVQPDKESSVTNDVGFSDDFSLLENKERCEEELIQLLTNILSCIMCKGLEKSDDDTWIERGQVFSALTKPGISSELLRPSDEIKLVLLQKMLEWAVTENREAKMNPVTAENAFRLTLIIQDFLQSEGLVNSNMWTEKLLEDLMLLFDSLSVWYSESPVGVKLSQIQIQLLLGFIGKGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPLTNGSASFFEDFQEYCSSNEWQVYIEKYIVPYMKKYETHTFYDSHESMALYWKDCYEALMVNMHKRDRDGGESKLKFQEFFVEPFNRKVRQENLRYNNMLKQLSSQQLATLRRWKAVKLYLTCERGPWAKRQQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDSLLLEVVKQVKVSDMEEDKLDLPEEEITSRVNIDEKEEQNQKEKLVLSEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQVREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNSYGTRSPQELFKASGLTQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPSVFRDLSKPIGVVNDKNAKATREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRTEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQVSKELVNDVVLPKWAKSAEDFICKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPSRLSAEEAVQKQAKTDTSTFNLFQHLPELKSFFIEGISDGIPLVKAIVPKNQSRSFMSQGSPELLITLSMNHIIGTHGWLPYDRNISNYFTFIRDQTVTNPKTQRSMNGPFAPGLEITSKLFIVSHDAKLLFSAGHWDNSIQVMSLTKGKLISHNIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPMGLASKPFQILYGHTDEVLSVAISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLLLTIPNLAISWEGHIVMYSSIEESTSLKDKNALHLFSVNGKYLGSQVLKEQVSDICIIGEHIVTGSLQGFLSIRDLHSLNLCISPLAMRSPIHCVCVTKEYSHILVGLEDGKLIVVGVGRPAEVKPSITDVVSRTFGDSLGSSLFQLNQTSPLWINKLKNKFDFSKYSK", "length": 2706, "header": "tr|A0ABI0P202-1|A0ABI0P202_BOVIN Computationally mapped isoform of Neurobeachin like 1 OS=Bos taurus OX=9913 GN=NBEAL1 PE=4 SV=1 CANONICAL=G3N3Y1-1" }, "locus": { "chromosome": "2", "start_pos": 91468765, "end_pos": 91318319, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148158.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148158.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105484.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105484.1" } ] } }, { "isoform_ac": "G3N3Y1-1", "url": "https://www.uniprot.org/uniprotkb/G3N3Y1/entry", "sequence": { "sequence": "MASRERLFELWMLYCSKKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDVPPGISLLPDNILQVLRIQLLQCVQKMADGLEEEQQALSILLVKFFIILCRNLSNVEEIGTCSYINHVITMTTLYIQQLKSKKKEKELADQTSIEEFVIHALAFCESLYDPYRNWRQRISGRIFSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQKNALQAISPATMEVLMRVLADCDSWEDGNPEEVGRKVELTLKCLTEVVHILLTSSSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKLFLNANSKVADKNEKDLANKLLTEMNEDQVFQGQLDYLAVSAIQALTAVMNKSPAAKEVFKERIGYTHMFEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELESHDLQVFISDWLKKICCINRQSRTTCVNANMGIRIIEALNSHSCLHRTCAENLIALHGSLGSQSVSSEEIRQLLRLLRVDESESVHPYTTPVTRAILTMARKQSLESALQYFNLSHSMAGISVPSIQKWPGSAFSFNAWFCLDQDQLTLGNANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITIVHMPGKRPFGQSLVYIYDNGQQKVSAPLRFPAMNEPFISCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTTEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEALQPPQVKALYLAGPNCLSPWKFQESDMADLPGNVLLHYTAKACKNAICLDLSTNCFHGRLTGNKVVNWDIKDVINCIGGLNVLFPLLEQISHFGEGQIPEGLNESTVSELITPVEGDWVVLTSTKASESRLERNLIATFILIVKHFIQRHPINQDNLIHSHGVAVLGALLQKVPSALMDVNVLMAIQLLIEQVSLEKNMQLLQQMYQYLLFDFHIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNDCKYNELSPDDIRTIRTSLYGLIKYFLSKGGTHEEIQSIMGYIAAINEEEQLLGILDILFSLLRTSPNRGQLFLLLFEPGNADILYALLLNQKYSDKLREIIFKVMEQMLKCTNVYERSKQRIRLREVGYSGFGLLLNEAPVNTSLIKSLTNQIINTDPAINFKDLLSVVYISHRAYINVRVVICRKMLQILQSQPDAAHQISQQVGWQDTLVKLFLKANFENGNTLHKHNRAIIVKDNDKNISVEDMKRSFDEKTDEEKIASFASAHVSSDEWSLEDRHSLDSNMPLFQEDSSMGELSFKSENQEEFWHNNPSPLSLDLSGIDSCELSDGGSQMPDSLPSTPSPVESMKPFPVQPDKESSVTNDVGFSDDFSLLENKERCEEELIQLLTNILSCIMCKGLEKSDDDTWIERGQVFSALTKPGISSELLRPSDEIKLVLLQKMLEWAVTENREAKMNPVTAENAFRLTLIIQDFLQSEGLVNSNMWTEKLLEDLMLLFDSLSVWYSESPVGVKLSQIQIQLLLGFIGKGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPLTNGSASFFEDFQEYCSSNEWQVYIEKYIVPYMKKYETHTFYDSHESMALYWKDCYEALMVNMHKRDRDGGESKLKFQEFFVEPFNRKVRQENLRYNNMLKQLSSQQLATLRRWKAVKLYLTCERGPWAKRQQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDSLLLEVVKQVKVSDMEEDKLDLPEEEITSRVNIDEKEEQNQKEKLVLSEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQVREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKVYSRLLSLHSPNSYGTRSPQELFKASGLTQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPSVFRDLSKPIGVVNDKNAKATREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRTEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQSNLGRLQVSKELVNDVVLPKWAKSAEDFICKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPSRLSAEEAVQKQAKTDTSTFNLFQHLPELKSFFIEGISDGIPLVKAIVPKNQSRSFMSQGSPELLITLSMNHIIGTHGWLPYDRNISNYFTFIRDQTVTNPKTQRSMNGPFAPGLEITSKLFIVSHDAKLLFSAGHWDNSIQVMSLTKGKLISHNIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPMGLASKPFQILYGHTDEVLSVAISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLLLTIPNLAISWEGHIVMYSSIEESTSLKDKNALHLFSVNGKYLGSQVLKEQVSDICIIGEHIVTGSLQGFLSIRDLHSLNLCISPLAMRSPIHCVCVTKEYSHILVGLEDGKLIVVGVGRPAEMRSGQLSRKLWGSSKRLSQISAGETEYNTQDSK", "length": 2722, "header": "tr|G3N3Y1-1|G3N3Y1_BOVIN Isoform 1 of Neurobeachin like 1 OS=Bos taurus OX=9913 GN=NBEAL1 PE=4 SV=4 CANONICAL=G3N3Y1-1" }, "locus": { "chromosome": "2", "start_pos": 91471374, "end_pos": 91318319, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065285.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065285.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056645.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056645.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T1397 is on non-canonical isoform A0AAA9SMR4-1 which maps to canonical isoform site G3N3Y1-1:1426", "icn3d_view": {}, "start_pos": 1426, "start_aa": "Thr", "end_pos": 1426, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1426", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T737 is on non-canonical isoform A0AAA9SMR4-1 which maps to canonical isoform site G3N3Y1-1:766", "icn3d_view": {}, "start_pos": 766, "start_aa": "Thr", "end_pos": 766, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr766", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:524280", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524280", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y1", "url": "https://www.uniprot.org/uniprotkb/G3N3Y1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y1", "url": "https://www.uniprot.org/uniprotkb/G3N3Y1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { 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"MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMSSPGLELPSCELSRLEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPALSQPRKHREFLTKTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEENMLSTLHSFIFFNKVEIVGMLQEDEKFLTDLFAQLTDEATDEEKRQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMDDTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITNKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVVENYWKALEDVDYVQTFKGLKLRFEQQRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNTDEDDMEDGEAVVSPSDKTKNDDDIMDPISKFMERKKLKESEEKEVLLKTNLSGRQSPSFKLSLSSGTKTTLSSQSPATNLPGSPGSPGSPGSPGSPGSIPKSTSQTAAITTKGGLVGLVDYPDDDEEDDEDDDKEDTLPLSKKAKFES", "length": 833, "header": "tr|F6R1L1-1|F6R1L1_BOVIN Isoform 1 of SMEK homolog 1 OS=Bos taurus OX=9913 GN=PPP4R3A PE=3 SV=2 CANONICAL=F6R1L1-1" }, "isoforms": [ { 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"MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMSSPGLELPSCELSRLEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPALSQPRKHREFLTKTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEENMLSTLHSFIFFNKVEIVGMLQEDEKFLTDLFAQLTDEATDEEKRQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMDDTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITNKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVVENYWKALEDVDYVQTFKGLKLRFEQQRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNTDEDDMEDGEAVVSPSDKTKNDDDIMDPISKFMERKKLKESEEKEVLLKTNLSGRQSPSFKLSLSSGTKTTLSSQSPATNLPGSPGSPGSPGSPGSPGSIPKSTSQTAAITTKGGLVGLVDYPDDDEEDDEDDDKEDTLPLSKKAKFES", "length": 833, "header": "tr|F6R1L1-1|F6R1L1_BOVIN Isoform 1 of SMEK homolog 1 OS=Bos taurus OX=9913 GN=PPP4R3A PE=3 SV=2 CANONICAL=F6R1L1-1" }, "locus": { "chromosome": "21", "start_pos": 56244692, "end_pos": 56211250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006650.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006650.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006650.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006650.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" }, { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "F6R1L1", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R1L1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 833, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R1L1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R1L1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" }, { "id": "PF22972", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22972" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PP4R3 EVH1-like", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 103, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6R1L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1L1" }, { "id": "PF04802", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 646, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 277 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 735, "end_pos": 737 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N018-1", "uniprot_ac": "G3N018", "uniprot_id": "G3N018_BOVIN", "mass": { "chemical_mass": 99933.0, "monoisotopic_mass": 99933.0 }, "refseq": { "ac": "NP_001073106", "name": "catenin alpha-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073106" }, "gene_names": [ { "name": "CTNNA3", "type": "recommended", "evidence": [ { "id": "G3N018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ] }, { "name": "CTNNA3", "type": "synonym", "evidence": [ { "id": "NP_001073106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073106" } ] } ], "protein_names": [ { "name": "Catenin alpha 3", "type": "synonym", "evidence": [ { "id": "G3N018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N018/entry#names_and_taxonomy" } ] }, { "name": "catenin (cadherin-associated protein), alpha 3", "type": "synonym", "evidence": [ { "id": "NP_001073106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073106" } ] }, { "name": "catenin alpha-3", "type": "synonym", "evidence": [ { "id": "NP_001073106", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073106" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CTNNA3", "url": "https://www.uniprot.org/uniprotkb/G3N018", "locus": { "chromosome": "28", "start_pos": 22282570, "end_pos": 24173253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045699", "url": "https://www.ensembl.org/id/ENSBTAG00000045699" } ] } } ], "crossref": [ { "id": "G3N018", "url": "https://alphafold.ebi.ac.uk/entry/G3N018", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045699", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "780777", "url": "https://www.ncbi.nlm.nih.gov/gene/780777", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:780777", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:780777", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWENYIH", "url": "https://omabrowser.org/oma/group/TWENYIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N018", "url": "https://www.orthodb.org/?gene=G3N018", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18914:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18914:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001073106", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073106", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SHH6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHH6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N018-1", "url": "https://www.uniprot.org/uniprotkb/G3N018-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAETPITLSINPQDLRVQTFTVEKLLEPLIIQVTTLVNCPQNPSNRKKGRSKRARVLLASVEEATWNLLDKGEKIAQEATVLKEELTGALEEVRKESEALKVSAERFADDPCYLPKREAVVQAARALLAAVTRLLVLADMIDVMCLLQHVSAFQRTFESLKNVSNKSDLKKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPILHSICSACLEHSDVASLKASKDTVCGEIQNALNVISNASQGIQNMLGPPEPQAATLGSALDELESLIVLDPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDFHRERIIAECNAIRQALQDLLSEYMNNTGKKERSNTLNMAIENMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLTEAAKNGREKEIKEYAAIFREHTSRLVEVANLACSMSTNEDGIKIVRVAANHLETLCPQIINAALALAARPKSQVVKKTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTAIPEFVTQVNVALEALSKNSLDVFDDSQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEDHEVRSHTSVQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDALARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPTGPRHPVVMWRMKAPAKKPLIKREKPEETYAAVRRGSAKKKIHPVQVMSEFRGRQVY", "length": 895, "header": "tr|G3N018-1|G3N018_BOVIN Isoform 1 of Catenin alpha 3 OS=Bos taurus OX=9913 GN=CTNNA3 PE=3 SV=1 CANONICAL=G3N018-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SHH6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHH6/entry", "sequence": { "sequence": "MSAETPITLSINPQDLRVQTFTVEKLLEPLIIQVTTLVNCPQNPSNRKKGRSKRARVLLASVEEATWNLLDKGEKIAQEATVLKEELTGALEEVRKESEALKVSAERFADDPCYLPKREAVVQAARALLAAVTRLLVLADMIDVMCLLQHVSAFQRTFESLKNVSNKSDLKKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPILHSICSACLEHSDVASLKASKDTVCGEIQNALNVISNASQGIQNMLGPPEPQAATLGSALDELESLIVLDPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDFHRERIIAECNAIRQALQDLLSEYMNNTGKKERSNTLNMAIENMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLTEAAKNGREKEIKEYAAIFREHTSRLVEVANLACSMSTNEDGIKIVRVAANHLETLCPQIINAALALAARPKSQVVKKTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSAIPEFVTQVNVALEALSKNSLDVFDDSQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEDHEVRSHTSVQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDALARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPTGPRHPVVMWRMKAPAKKPLIKREKPEETYAAVRRGSAKKKIHPVQVMSEFRGRQVY", "length": 828, "header": "tr|A0AAA9SHH6-1|G3N018_BOVIN Computationally mapped isoform of Catenin alpha 3 OS=Bos taurus OX=9913 GN=CTNNA3 PE=3 SV=1 CANONICAL=G3N018-1" }, "locus": { "chromosome": "28", "start_pos": 24121400, "end_pos": 22282912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132723.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132723.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081948.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081948.1" } ] } }, { "isoform_ac": "G3N018-1", "url": "https://www.uniprot.org/uniprotkb/G3N018/entry", "sequence": { "sequence": "MSAETPITLSINPQDLRVQTFTVEKLLEPLIIQVTTLVNCPQNPSNRKKGRSKRARVLLASVEEATWNLLDKGEKIAQEATVLKEELTGALEEVRKESEALKVSAERFADDPCYLPKREAVVQAARALLAAVTRLLVLADMIDVMCLLQHVSAFQRTFESLKNVSNKSDLKKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPILHSICSACLEHSDVASLKASKDTVCGEIQNALNVISNASQGIQNMLGPPEPQAATLGSALDELESLIVLDPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDFHRERIIAECNAIRQALQDLLSEYMNNTGKKERSNTLNMAIENMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLTEAAKNGREKEIKEYAAIFREHTSRLVEVANLACSMSTNEDGIKIVRVAANHLETLCPQIINAALALAARPKSQVVKKTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTAIPEFVTQVNVALEALSKNSLDVFDDSQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEDHEVRSHTSVQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDALARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPTGPRHPVVMWRMKAPAKKPLIKREKPEETYAAVRRGSAKKKIHPVQVMSEFRGRQVY", "length": 895, "header": "tr|G3N018-1|G3N018_BOVIN Isoform 1 of Catenin alpha 3 OS=Bos taurus OX=9913 GN=CTNNA3 PE=3 SV=1 CANONICAL=G3N018-1" }, "locus": { "chromosome": "28", "start_pos": 24121400, "end_pos": 22282912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063012.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063012.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055173.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:780777", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:780777", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JX81-1", "protein_name": "Catenin alpha 3", "gene_name": "Ctnna3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLRRRPGVEVLSDLWIGNMSAETPITLQMDMQDLQIQTFTVEKLLEPLIIQVTTLVNCPQNPSNRKKGRSKRARVLLASVEEATWNLLDKGEMIAKEATVLKEDLEAALQEVRKESKALKGSAERFTDDPCYLPKREAVVQAARALLAAVTRLLILADMTDVMCLLQHVSSFQRTFKSLKNVSNKSDLQKTYQKLGKELERLDRFAFKRQQDLKSPSQRDEIAGARATLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALDVISNASQGIQNVPASLEPQAATLGSALDELENLIVLNPLTVTEEDLRPPLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMSNIGKTERSNTLNTAIVNMSKKTRDLRRQLRKAIIDHISDSFLDTTVPLLVLIEAAKNGQVKEIKDYASIFHEHTGRLMEVANLACSMSTNEDGIKIVRIAANHLETLCPQIINAALALASRPKSQVVKNTMEMYKRTWEHYIHVLTEAVDDITSIDDFLAVSESHILEDVNRCIIALRDQDADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAYTEGVMRNVNLLTSIVIPEFVTQVNVALDALSKNALTALDDNQFVDISKKIYDTIHDIRCSVMIIRTPEELEDVSDLEDDHEVRSHTSTQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPPCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIVSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSSAGPRHPVVMWRMKAPAKKPLIKREKPEETWAVVRRGSAKKKIHPVQVMSEFRGRQVY", "length": 914 }, "evidence": [ { "id": "G3N018", "url": "https://omabrowser.org/oma/group/G3N018/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XWR2-1", "protein_name": "Catenin alpha 3", "gene_name": "CTNNA3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDRLYSSIGEMSTKVPNIKLKIDPQDLQIQTFTVEKLLEPLIIQVTTLVKCPQNPSGKKKGRSKRARILLASVEEATQNLLDKGEKIAKEAVVLKEELHAALADVQKESQALKISAEAFTGDPCYLPKRQAVVQTARSLLTAVTRLLILADMVDVAYLLEHLTVFQRTFETLRNVSSKSDLQNTYQKFQKDLENLDYLAYKRQQDLKSSDQRDEIAAARATLKENSSLLHSVCSACLEHSDVASLTASKDSICSEIQNALNVISNASQGVGNKKGQPASYRATLGSALDELEHLIIQDPLVVSEEKIRPSLEKRLEAIISGAALLADSSCTRDFHRERIIAECNAIRQALQDLLSEYINNTDRKERSDALNTAIDSMCKKTRDLRRQLRKAIIDHISDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFREHTGRLVEVANLACSLSTNEDGMKIVQMAANHLETLCPQVINAALALSARPKSQVVKNNMEMYRSIWENHVHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALREQNADNLDRAAGAIRGRASRVAHIVSGEMDNYEPGAYTEGVMKNVQYLTKSVIPEFISQVNIALESLSKNTVHLFDDNQFVDVSKKVYDTIHTIRCSVMMIRTPEELEDVSDLEDHDTRSRTSIQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKRMCVIMMEMTDFTRGRGPLKNTSDVINAAKMISESGSRMDVLARLIANQCPDQSCKQDLLAYLEQIKLYSHQLKICSQVRAEIQNLGGELIVSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIKIQSPTGPRHPVVMWRMKAPEKKPLIKREKPEEIYAAVRKGSAKKRIHPVQVMSEFRGREIV", "length": 905 }, "evidence": [ { "id": "G3N018", "url": "https://omabrowser.org/oma/group/G3N018/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q65CL1-1", "protein_name": "Catenin alpha-3", "gene_name": "Ctnna3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAETPITLNMDTQDLQIQTFTVEKLLEPLIIQVTTLVNCPQNPSNRKKGRSKRARVLLASVEEATWNLLDKGEMIAKEATVLKEELAAALQEVRKESKALKVSAERFTDDPCYLPKREAVVQAARALLAAVTRLLVLADMIDVMCLLQHVSSFQRTFESLKNVSNKSDLQRTYQKLGKELESLDYLAFKRQQDLKSPSQRDEIAGARATLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALDVISNASQGIQNAPAPPEPQAATLGSAFDELENLIVLNPLTVTEEDVRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLTEYMSNTGKTERSNTLNTAIVNMSKKTRDLRRQLRKAIIDHISDSFLDTTVPLLVLIEAAKNGRVKEIKDYAAIFHEHTGRLVEVANLACSMSTNEDGIKIVRIAANHLETLCPQIINAALALASRPKSQVVKNTMEMYKRTWEHYIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALDALSKNSLTALDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEDDHEVRSHTSIQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPPCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIVSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSSAGPRHPVVMWRMKAPAKKPLIKREKPEETWAAVRRGSAKKKIHPVQVMSEFRGRQVY", "length": 895 }, "evidence": [ { "id": "G3N018", "url": "https://omabrowser.org/oma/group/G3N018/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UI47-1", "protein_name": "Catenin alpha-3", "gene_name": "CTNNA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNASQGIQNMTTPPEPQAATLGSALDELENLIVLNPLTVTEEEIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEYAAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQAVKNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALSKSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEEEHEVRSHTSIQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSPAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMSEFRGRQIY", "length": 895 }, "evidence": [ { "id": "G3N018", "url": "https://omabrowser.org/oma/group/G3N018/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "fascia adherens", "id": "GO:0005916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005916", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "regulation of heart rate by cardiac conduction", "id": "GO:0086091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086091", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "regulation of ventricular cardiac muscle cell action potential", "id": "GO:0098911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098911", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "bundle of His cell-Purkinje myocyte adhesion involved in cell communication", "id": "GO:0086073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086073", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "G3N018", "url": "https://www.uniprot.org/uniprotkb/G3N018" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N018-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 895, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N018-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N018" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 166, "end_pos": 168 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 348, "end_pos": 350 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RR01-1", "uniprot_ac": "F6RR01", "uniprot_id": "F6RR01_BOVIN", "mass": { "chemical_mass": 40140.0, "monoisotopic_mass": 40140.0 }, "refseq": {}, "gene_names": [ { "name": "RPF1", "type": "recommended", "evidence": [ { "id": "F6RR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR01" } ] } ], "protein_names": [ { "name": "Ribosome production factor 1", "type": "recommended", "evidence": [ { "id": "F6RR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR01/entry#names_and_taxonomy" } ] }, { "name": "Brix domain-containing protein 5", "type": "synonym", "evidence": [ { "id": "F6RR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR01/entry#names_and_taxonomy" } ] }, { "name": "Ribosome biogenesis protein RPF1", "type": "synonym", "evidence": [ { "id": "F6RR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR01/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be required for ribosome biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01#function" }, { "database": "UniProtKB", "id": "ARBA00037314", "url": "https://www.uniprot.org/uniprotkb/ARBA00037314#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPF1", "url": "https://www.uniprot.org/uniprotkb/F6RR01", "locus": { "chromosome": "3", "start_pos": 59600699, "end_pos": 59617167, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008118", "url": "https://www.ensembl.org/id/ENSBTAG00000008118" } ] } } ], "crossref": [ { "id": "F6RR01", "url": "https://alphafold.ebi.ac.uk/entry/F6RR01", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008118", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008118", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AWIISNK", "url": "https://omabrowser.org/oma/group/AWIISNK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RR01", "url": "https://www.orthodb.org/?gene=F6RR01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22734", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22734", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22734:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22734:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SL05", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SL05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RR01-1", "url": "https://www.uniprot.org/uniprotkb/F6RR01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKAGGKSGGSGKKGLKRKAATEESQEAAVGEDGTTESGVQPPKTAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETIVDPNDEEVAYDEATDEFASYFNRQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCISRDFTDLIVINEDRKIPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL", "length": 349, "header": "tr|F6RR01-1|F6RR01_BOVIN Isoform 1 of Ribosome production factor 1 OS=Bos taurus OX=9913 GN=RPF1 PE=4 SV=1 CANONICAL=F6RR01-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SL05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL05/entry", "sequence": { "sequence": "MAKAGGKSGGSGKKGLKRKAATEESQEAAVGEDGTTESGVQPPKTAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETIVDPNDEEVMLEVLNK", "length": 130, "header": "tr|A0AAA9SL05-1|F6RR01_BOVIN Computationally mapped isoform of Ribosome production factor 1 OS=Bos taurus OX=9913 GN=RPF1 PE=4 SV=1 CANONICAL=F6RR01-1" }, "locus": { "chromosome": "3", "start_pos": 59617143, "end_pos": 59613275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090777.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090777.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083322.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083322.1" } ] } }, { "isoform_ac": "F6RR01-1", "url": "https://www.uniprot.org/uniprotkb/F6RR01/entry", "sequence": { "sequence": "MAKAGGKSGGSGKKGLKRKAATEESQEAAVGEDGTTESGVQPPKTAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETIVDPNDEEVAYDEATDEFASYFNRQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCISRDFTDLIVINEDRKIPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL", "length": 349, "header": "tr|F6RR01-1|F6RR01_BOVIN Isoform 1 of Ribosome production factor 1 OS=Bos taurus OX=9913 GN=RPF1 PE=4 SV=1 CANONICAL=F6RR01-1" }, "locus": { "chromosome": "3", "start_pos": 59617143, "end_pos": 59600949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010676.4", "url": "https://www.ensembl.org/id/ENSBTAT00000010676.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010676.4", "url": "https://www.ensembl.org/id/ENSBTAP00000010676.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UZQ8-1", "protein_name": "Ribosome production factor 1", "gene_name": "RPF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKAGDKNGGGGKKGLKRKAATLEPQEAAVSEDGTTESGVQPTTAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETIVDPNDEEVAYDEATDEFASYFNRQTCPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCISRDFTDLIVINEDRKIPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHTPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL", "length": 349 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZMJ4-1", "protein_name": "Ribosome production factor 1", "gene_name": "RPF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGPEVRVFLPVAHAPSALPAERRGRGAAQRSMAGGGAGMGTDSGPGSGPGPGPAGQNVEPAAPERVLFPPTFSVSEIKNKQRRHFMFLRWKQQQRKEKLALKKKRRKEREALGDKAPPKAIPKTIENQRIYDETTVDPNDEEVAFDIATDEFAPYFNRQTVPKILITTSDRPRGRTVRFCEQLSTVIPNSHVYYRRGLALKRIIPQCIARDFTDLIVINEDRKIPNGLVLSHLPDGPTAHFRMSSVRLRKEIKRKGKEPTEHVPEVILNNFTTRLGHSIGRMFASLFPHDPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKFGEYEWIHKRREMDTSRRKFHL", "length": 369 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P38805-1", "protein_name": "Ribosome production factor 1", "gene_name": "RPF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MALGNEINITNKLKRQEIFADIKHEKNKERHTMRRKRAKEERENPELREQRLKENVTQTIENTRVYDETINKEVEGDEDDLMRYFNSNSNEPPKIFLTTNVNAKKSAYEFANILIEILPNVTFVKRKFGYKLKEISDICIKRNFTDIVIINEDKKKVTGLTFIHLPEGPTFYFKLSSFVEVKKIVGHGRPTSHIPELILNNFQTRLGQTVGRLFQSILPQNPDIEGRQVITLHNQRDYIFFRRHRYVFKDNERVGLQELGPQFTLKLKRLQRGIKEETEWEHKPEMDKEKKKFYL", "length": 295 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54MN3-1", "protein_name": "Brix domain-containing protein", "gene_name": "bxdc5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVKPKKEVDKDDLTKEELKLRRSPTDIKCKAKRVLLVQKLQAAKKTAREKARKQRKKEREILGDAAPAKEVPRTIESMRRADETIVDTENDKEFEEEINKDEFESYFDGRVPKIVVTTNQRSTKEAVEFAQVFTKLLPNCEFFHRRKYHLKEIVQFCNNRDYTDIIVVNETKGIIDELTISHLPNGPTAVFRLTNLVMPEDIPGGGEMTSHKAELIVNNFTTRLGHSIGRMFASMFAQDPNFKGRRVCTLHNQRDFIFFRQHRYIFESKEDANVQELGPRFTLKLKSLQKGSFNTSTGEYIHLHQHNMDVDRKKFVL", "length": 317 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RJS9-1", "protein_name": "Ribosome production factor 1", "gene_name": "Rpf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKAGEKSGGGGKRGLKRKAPAEEPQETAVASDGTAESGVQSAKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKREREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNRQTSPKILITTSDRPHGRTVRLCEQLSTVIPDSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHVPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKVCAYCSKAI", "length": 345 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TND5-1", "protein_name": "Ribosome production factor 1", "gene_name": "Rpf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKAGEKSVGGGKRGLKRKAAAEEPQEAAAASDGTAESGVQPAKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNRQTSPKILITTSDRPHGRTVRLCEQLSTVIPDSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHVPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL", "length": 349 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H9Y2-1", "protein_name": "Ribosome production factor 1", "gene_name": "RPF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKAGDKSSSSGKKSLKRKAAAEELQEAAGAGDGATENGVQPPKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL", "length": 349 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M125-1", "protein_name": "Ribosomal RNA processing Brix domain protein", "gene_name": "MEE49", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGFKRKKDDGDGEEMESDVRGKSTFSGGEKRNVILPSMIKNKDKRSKVYAKQKHEKKLEKQKKIRARDAAEKRALELGEEPPQKMIPKTIENTRESDETVCRPDDEELFADIDADEFNPVLRREIAPKVLLTTCRFNSTRGPALISELLSVIPNSHYQKRGTYDLKKIVEYATKKDFTSLIVVHTNRREPDALLIIGLPNGPTAHFKLSNLVLRKDIKNHGNPTSHQPELVLNNFTTRLGNRVGRFFQSLFPPDPNFRGRRVVTFHNQRDFIFFRHHRYIFETKESKSDKGKEETIKPRLQECGPRFTLKLVTLQHGTFDTKGGEFEWVHKPEMDTSRRRFFL", "length": 343 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VKB4-1", "protein_name": "Probable ribosome production factor 1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIKIKRKTAPPPVEQDSDSDSSFDEEEPQDLEVQEGPVTDSSDEEAASSSKKTAKQGEASEDLKEEDDDDDEEENDDDDEEEDDDDDDDKKTRIPVLNPLSWMRNKEQRLALYKKMKKEKHKKKMQERRARRKAGVPANPGHTIESLREKDQTEVANLNDSDNEELQKELQLDDFSSYFERSYEPKVLITFADNPVTKTRKFGLELSRIFPNALVKIRNKSSVKKICKSAEREEFTDVVIVNEDRRKPNGLLVIHLPNGPTAHFKLSNVKLTSDIKRDHKEITKHRPEVILNNFTTRLGLTVGRMLGALFHHDPEFRGRRAVTFHNQRDYIFFRHHRYEFTKEGKRVKLRELGPRFTLKLRSLQEGTFDSKTGDYAWIISNKRHAMESRRRFFL", "length": 394 }, "evidence": [ { "id": "F6RR01", "url": "https://omabrowser.org/oma/group/F6RR01/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "rRNA primary transcript binding", "id": "GO:0042134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042134", "evidence": [ { "database": "UniProtKB", "id": "F6RR01", "url": "https://www.uniprot.org/uniprotkb/F6RR01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RR01-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 349, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RR01-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RR01" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR01" }, { "id": "PS50833", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50833" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Brix", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 325, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7U6-1", "uniprot_ac": "G3X7U6", "uniprot_id": "G3X7U6_BOVIN", "mass": { "chemical_mass": 28410.0, "monoisotopic_mass": 28410.0 }, "refseq": {}, "gene_names": [ { "name": "UTP23", "type": "recommended", "evidence": [ { "id": "G3X7U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ] } ], "protein_names": [ { "name": "rRNA-processing protein UTP23 homolog", "type": "recommended", "evidence": [ { "id": "G3X7U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7U6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in rRNA-processing and ribosome biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SMZ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMZ6#function" }, { "database": "UniProtKB", "id": "ARBA00037300", "url": "https://www.uniprot.org/uniprotkb/ARBA00037300#function" }, { "database": "UniProtKB", "id": "A0AAA9TKN6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKN6#function" }, { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UTP23", "url": "https://www.uniprot.org/uniprotkb/G3X7U6", "locus": { "chromosome": "14", "start_pos": 47465065, "end_pos": 47552999, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040422", "url": "https://www.ensembl.org/id/ENSBTAG00000040422" } ] } } ], "crossref": [ { "id": "G3X7U6", "url": "https://alphafold.ebi.ac.uk/entry/G3X7U6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040422", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040422", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534858", "url": "https://www.ncbi.nlm.nih.gov/gene/534858", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534858", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534858", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCMQALY", "url": "https://omabrowser.org/oma/group/CCMQALY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7U6", "url": "https://www.orthodb.org/?gene=G3X7U6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069507", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SMZ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKN6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKN6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2I2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2I2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7U6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7U6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMAETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFLATQDQNLSMKVKKKPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVKDPEQRRRKKRKKVSGPNPLSCLKKKKKTQDTNSSASEKKRKRKRIRNRSTSEVLSEKQNAEG", "length": 248, "header": "tr|G3X7U6-1|G3X7U6_BOVIN Isoform 1 of rRNA-processing protein UTP23 homolog OS=Bos taurus OX=9913 GN=UTP23 PE=3 SV=1 CANONICAL=G3X7U6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SMZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMZ6/entry", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMAETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFLATQDQNLSMKVKKKPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVKDPEQRRRKKRKKVSGPNPLSCLKKKKKTQDTNSSASEKKRKRKRIRNRSTSEVLSEKQNAEGHREQIYGYQGEKDGGDTESCAKATDMEPRTNQRAPEEPTSGTEQTPL", "length": 295, "header": "tr|A0AAA9SMZ6-1|G3X7U6_BOVIN Computationally mapped isoform of rRNA-processing protein UTP23 homolog OS=Bos taurus OX=9913 GN=UTP23 PE=3 SV=1 CANONICAL=G3X7U6-1" }, "locus": { "chromosome": "14", "start_pos": 47552908, "end_pos": 47537724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118093.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118093.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087718.1" } ] } }, { "isoform_ac": "A0AAA9TKN6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKN6/entry", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMAETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFLATQDQNLSMKVKKKPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVKDPEQRRRKKRKKVSGPNPLSCLKKKKKTQDTNSSASEKKRKRKRIRNRSTSEVLSEKQNAEGHLLFIHHEACHLQEIKVVEWTERGPIVSTNDSIHMPPPFTPWGGRKTN", "length": 296, "header": "tr|A0AAA9TKN6-1|G3X7U6_BOVIN Computationally mapped isoform of rRNA-processing protein UTP23 homolog OS=Bos taurus OX=9913 GN=UTP23 PE=3 SV=1 CANONICAL=G3X7U6-1" }, "locus": { "chromosome": "14", "start_pos": 47552908, "end_pos": 47466069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119196.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119196.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097512.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097512.1" } ] } }, { "isoform_ac": "A0ABI0P2I2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I2/entry", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMAETQLCTTRKQCQKPLMFSLSLHWYLKTMKHLLGPFVPPSLLLILIAP", "length": 102, "header": "tr|A0ABI0P2I2-1|A0ABI0P2I2_BOVIN Computationally mapped isoform of UTP23 small subunit processome component OS=Bos taurus OX=9913 GN=UTP23 PE=4 SV=1 CANONICAL=G3X7U6-1" }, "locus": { "chromosome": "14", "start_pos": 47552908, "end_pos": 47425429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136793.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136793.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107052.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107052.1" } ] } }, { "isoform_ac": "G3X7U6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7U6/entry", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMAETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFLATQDQNLSMKVKKKPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVKDPEQRRRKKRKKVSGPNPLSCLKKKKKTQDTNSSASEKKRKRKRIRNRSTSEVLSEKQNAEG", "length": 248, "header": "tr|G3X7U6-1|G3X7U6_BOVIN Isoform 1 of rRNA-processing protein UTP23 homolog OS=Bos taurus OX=9913 GN=UTP23 PE=3 SV=1 CANONICAL=G3X7U6-1" }, "locus": { "chromosome": "14", "start_pos": 47552908, "end_pos": 47547729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046494.4", "url": "https://www.ensembl.org/id/ENSBTAT00000046494.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043790.3", "url": "https://www.ensembl.org/id/ENSBTAP00000043790.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534858", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534858", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IA74-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "utp23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKIKRQKHAKKTISFYKYNFSFREPFQILIDGTFCQAALKNKIQIKEQLPKYLMGEIQLCTTNCALKELESLAKDLYGAKLILQRFQIRKCKHMKDPVPASECLLSMLAETNPHHYFIATQDQQLTTALKKIPGVPLLYIILNTMVLDKPSERTLKHVEAVQLGEIVNPAQQKSLQSLKEKEGISGDAEKRGRKRKRKQSNPNPLSCLKKKKKKATPQQPKNPDGEKKRKRSRHRKHKPAGGEQTEVRSLTSGGQSV", "length": 257 }, "evidence": [ { "id": "G3X7U6", "url": "https://omabrowser.org/oma/group/G3X7U6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Y428-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "UTP23", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKITRQKHAKKNMGFYKHNFQFREPFQVLVDGTFCHAALRNKIQIREQLPGYLGGATQLCTTRCILKELESLGKALYGAKLIAQSFQVRSCSHHKDPVGGSACLLSMVEEGNPHHFFVATQDQDLANKVKKKAGIPLLFIIQNTMVLDKPSPKSLAFVQTLQTSQLVPEHQKQSIVQLKEKEGLAKQEGEKRRKRKRAGGPNPLSCLKKKKKTQESQKPAEKKKRRRKRIRVKTEAMQSVQKNEKE", "length": 246 }, "evidence": [ { "id": "G3X7U6", "url": "https://omabrowser.org/oma/group/G3X7U6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S1J8-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "UTP23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILVDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEDGNPHHYFVATQDQNLSMKIKKRPGIPLMFIIQNTIVLDKPSPKTIAFVKAVESGQLVSVHEKQSIRQLKEEQGLVRDPELRRRKKRKKISGPNPLSCLKKKKKAQGTNSSPSEKKRKRKRIRNRSTSKVLSEKQNNAEAEG", "length": 251 }, "evidence": [ { "id": "G3X7U6", "url": "https://omabrowser.org/oma/group/G3X7U6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q12339-1", "protein_name": "rRNA-processing protein UTP23", "gene_name": "UTP23", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRQKRAKSYRKQLLVYSHTFKFREPYQVLVDNQLVLECNNSNFNLPSGLKRTLQADVKVMITQCCIQALYETRNDGAINLAKQFERRRCNHSFKDPKSPAECIESVVNISGANKHRYVVASQDIDLRRKLRTVPGVPLIHLTRSVMVMEPLSTASAKASKITEEQKLYKGLNDPNIEKLQESGDGSGKESITKKRKLGPKAPNPLSVKKKKKVNSPSDEVKDKEDTSKEKKKRRRRKHKSNTNVPVSNGTTAAQ", "length": 254 }, "evidence": [ { "id": "G3X7U6", "url": "https://omabrowser.org/oma/group/G3X7U6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9BRU9-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "UTP23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEEGNPHHYFVATQDQNLSVKVKKKPGVPLMFIIQNTMVLDKPSPKTIAFVKAVESGQLVSVHEKESIKHLKEEQGLVKNTEQSRRKKRKKISGPNPLSCLKKKKKAPDTQSSASEKKRKRKRIRNRSNPKVLSEKQNAEGE", "length": 249 }, "evidence": [ { "id": "G3X7U6", "url": "https://omabrowser.org/oma/group/G3X7U6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CX11-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "Utp23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLRDQLPRYLMGETQLCTTRCVLKELETLGKELYGAKLIAQKCQVRNCPHFKSPVSGSECLLSMVDEGNPHHYFVATQDQNLSVKVKRTPGIPLMFIIQNTIVLDKPSPRTVAFVKAVEAGQLVSVHEKQSIKQLKEEQGLVRNPDLRRRRRKKKKVGGPNPLSCLKKKKKAQDTKSPASEKKRKRKRIRNRSTLKVSSEQQGAEG", "length": 249 }, "evidence": [ { "id": "G3X7U6", "url": "https://omabrowser.org/oma/group/G3X7U6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQ40-1", "protein_name": "rRNA-processing protein UTP23 homolog", "gene_name": "Dmel\\CG17652", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKISRFKKSHKTLVFFASNFDYREPYQVLIDATFCQAALQQKIGIDEQIKKYFQCGVKLLTTQCVILESESLGAPLTGATSIVKRFHVHKCGHEGKPVPASECIKSMTKDNRYVVASQDRLLQESLRKIPGRCLLYLHKATPVLEAPSKASKKWVQRRAKNLMLGKQVEKIDYMKEKQGLKPAETAVKPKKHKGPKNPNPLSCKKSKKDKAKQQLKGVEQTAITKAKRKRVKIPAHVKAALGKD", "length": 244 }, "evidence": [ { "id": "G3X7U6", "url": "https://omabrowser.org/oma/group/G3X7U6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ], "pmid": "" }, { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ], "pmid": "" }, { "name": "small ribosomal subunit rRNA binding", "id": "GO:0070181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070181", "evidence": [ { "database": "UniProtKB", "id": "G3X7U6", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7U6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 248, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7U6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7U6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7U6" }, { "id": "PF24779", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24779" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UTP23 sensor motif region", "eco_id": "ECO_0000259", "start_pos": 193, "end_pos": 212, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 233, "end_pos": 235 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"MMFGSGRQHFQWPWGKDERQGPSQCLEHPAWTREHVWALPAHWKPTQPSLQTGLPRLPGGSQRGTGSPMQDSEAPGHDVTYTSHPPWWECGSPRLRPGRFHAGAADDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSGLGSCQLFLSTVPVLWTLLGS", "length": 265, "header": "tr|G3N3T2-1|G3N3T2_BOVIN Isoform 1 of Ephrin A2 OS=Bos taurus OX=9913 GN=FAM174C PE=3 SV=2 CANONICAL=G3N3T2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SNS9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNS9/entry", "sequence": { "sequence": "MPAGKEAAPEAGSVQPLSCLLLLTQQLSLTSARRDSLTVQHRPWRFHAGAADDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMEHYVLYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNAVDRPCLRLKVYVRPTNETLYEAPEPIFTSNNSCSGLGSCQLFLSTVPVLWTLLGS", "length": 211, "header": "tr|A0AAA9SNS9-1|G3N3T2_BOVIN Computationally mapped isoform of Ephrin A2 OS=Bos taurus OX=9913 GN=FAM174C PE=3 SV=1 CANONICAL=G3N3T2-1" }, "locus": { "chromosome": "7", "start_pos": 43735976, "end_pos": 43724510, 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"Protein Classification" ] }, { "id": "PTHR46016:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46016:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SPC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RFN8", "url": "https://www.uniprot.org/uniprotkb/F6RFN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RFN8-1", "url": "https://www.uniprot.org/uniprotkb/F6RFN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMFRSLVGSAQQRQPPGGPAGGDSALEAQYSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKAAHVEKQLASYKAPCRGCSKKVTLAKMRVHVSSCMKVQEQMANCPKFVPVVPTSQPIPSAVPNRSTFACPYCGARNLDQQELVKHCVDNHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVHRRGGCLPGRPGPVSLRELTVPPPAEPSHLQGQSPPAPAPKPAWEGASRAGQNRIAARGEATSPPPALLLSAAGSSVLGLSTWPRGVASAAPVRVSKPCCPPCQEDPSGPSTQQGHAGAQPSTWQRFPLARSVLAFVIPRGSALFYIIRCDDLFTFSRAKTEQLPFILQYLCLTRNNSIFMEHLQNYIF", "length": 405, "header": "tr|F6RFN8-1|F6RFN8_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RNF166 OS=Bos taurus OX=9913 GN=RNF166 PE=4 SV=1 CANONICAL=F6RFN8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC5/entry", "sequence": { "sequence": "MAMFRSLVGSAQQRQPPGGPAGGDSALEAQYSCPICLEVQEQMANCPKFVPVVPTSQPIPSAVPNRSTFACPYCGARNLDQQELVKHCVDNHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN", "length": 156, "header": "tr|A0AAA9SPC5-1|F6RFN8_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase RNF166 OS=Bos taurus OX=9913 GN=RNF166 PE=4 SV=1 CANONICAL=F6RFN8-1" }, "locus": { "chromosome": "18", "start_pos": 13932669, "end_pos": 13925307, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127977.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127977.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085777.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085777.1" } ] } }, { "isoform_ac": "F6RFN8-1", "url": "https://www.uniprot.org/uniprotkb/F6RFN8/entry", "sequence": { "sequence": "MAMFRSLVGSAQQRQPPGGPAGGDSALEAQYSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKAAHVEKQLASYKAPCRGCSKKVTLAKMRVHVSSCMKVQEQMANCPKFVPVVPTSQPIPSAVPNRSTFACPYCGARNLDQQELVKHCVDNHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVHRRGGCLPGRPGPVSLRELTVPPPAEPSHLQGQSPPAPAPKPAWEGASRAGQNRIAARGEATSPPPALLLSAAGSSVLGLSTWPRGVASAAPVRVSKPCCPPCQEDPSGPSTQQGHAGAQPSTWQRFPLARSVLAFVIPRGSALFYIIRCDDLFTFSRAKTEQLPFILQYLCLTRNNSIFMEHLQNYIF", "length": 405, "header": "tr|F6RFN8-1|F6RFN8_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RNF166 OS=Bos taurus OX=9913 GN=RNF166 PE=4 SV=1 CANONICAL=F6RFN8-1" }, "locus": { "chromosome": "18", "start_pos": 13932669, "end_pos": 13924795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027892.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027892.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027892.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027892.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RFN8", "url": "https://www.uniprot.org/uniprotkb/F6RFN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RFN8", "url": "https://www.uniprot.org/uniprotkb/F6RFN8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F6RFN8", "url": "https://www.uniprot.org/uniprotkb/F6RFN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFN8" }, { "id": "PS51803", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51803" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2HC RNF-type", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 117, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFN8" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 73, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 392, "end_pos": 394 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G1K1B6-1", "uniprot_ac": "G1K1B6", "uniprot_id": "G1K1B6_BOVIN", "mass": { "chemical_mass": 19378.0, "monoisotopic_mass": 19378.0 }, "refseq": {}, "gene_names": [ { "name": "POP5", "type": "recommended", "evidence": [ { "id": "G1K1B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K1B6" } ] } ], "protein_names": [ { "name": "Ribonuclease P/MRP protein subunit POP5", "type": "recommended", "evidence": [ { "id": "G1K1B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K1B6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SV43", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV43#function" }, { "database": "UniProtKB", "id": "PIRNR023803", "url": "https://www.uniprot.org/uniprotkb/PIRNR023803#function" }, { "database": "UniProtKB", "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6#function" }, { "database": "UniProtKB", "id": "ARBA00056519", "url": "https://www.uniprot.org/uniprotkb/ARBA00056519#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "POP5", "url": "https://www.uniprot.org/uniprotkb/G1K1B6", "locus": { "chromosome": "17", "start_pos": 62851538, "end_pos": 62853815, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005385", "url": "https://www.ensembl.org/id/ENSBTAG00000005385" } ] } } ], "crossref": [ { "id": "G1K1B6", "url": "https://alphafold.ebi.ac.uk/entry/G1K1B6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005385", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005385", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MQNYLDK", "url": "https://omabrowser.org/oma/group/MQNYLDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G1K1B6", "url": "https://www.orthodb.org/?gene=G1K1B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48414:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48414:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SV43", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SV43-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G1K1B6-1", "url": "https://www.uniprot.org/uniprotkb/G1K1B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRFKHRYLLCEVVSDDPRCRLTLEDRVLGTLVRDTIARVHGTFGAAACSIGFAVRYLNAYTGIVLLRCRKEFYRLVWSALPFITSLENKGHRYPCFLNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTKNCLLEEESAGEELSDSGGEETAEPME", "length": 170, "header": "tr|G1K1B6-1|G1K1B6_BOVIN Isoform 1 of Ribonuclease P/MRP protein subunit POP5 OS=Bos taurus OX=9913 GN=POP5 PE=3 SV=1 CANONICAL=G1K1B6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SV43-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV43/entry", "sequence": { "sequence": "MVRFKHRYLLCEVVSDDPRCRLTLEDRVLGTLVRDTIARVHGTFGAAACSIGFAGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTKNCLLEEESAGEELSDSGGEETAEPME", "length": 120, "header": "tr|A0AAA9SV43-1|G1K1B6_BOVIN Computationally mapped isoform of Ribonuclease P/MRP protein subunit POP5 OS=Bos taurus OX=9913 GN=POP5 PE=3 SV=1 CANONICAL=G1K1B6-1" }, "locus": { "chromosome": "17", "start_pos": 62853778, "end_pos": 62851822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131154.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131154.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087841.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087841.1" } ] } }, { "isoform_ac": "G1K1B6-1", "url": "https://www.uniprot.org/uniprotkb/G1K1B6/entry", "sequence": { "sequence": "MVRFKHRYLLCEVVSDDPRCRLTLEDRVLGTLVRDTIARVHGTFGAAACSIGFAVRYLNAYTGIVLLRCRKEFYRLVWSALPFITSLENKGHRYPCFLNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTKNCLLEEESAGEELSDSGGEETAEPME", "length": 170, "header": "tr|G1K1B6-1|G1K1B6_BOVIN Isoform 1 of Ribonuclease P/MRP protein subunit POP5 OS=Bos taurus OX=9913 GN=POP5 PE=3 SV=1 CANONICAL=G1K1B6-1" }, "locus": { "chromosome": "17", "start_pos": 62853778, "end_pos": 62851822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007083.5", "url": "https://www.ensembl.org/id/ENSBTAT00000007083.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007083.3", "url": "https://www.ensembl.org/id/ENSBTAP00000007083.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZY31-1", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "gene_name": "Pop5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRFKHRYLLCELVSEDPRCRLSLDDRVLGGLVRDTIARVHGAFGAAACSVGFAVRYLNAYTGVVLLRCRKDFYQLVWSALPFITCLENKGHRYSCFFNTLHVGGTIRTCQKFLIQYNRRQLLVLLQNYTDEGEREAIKKSVSRSCLLDRESVEELSDSAGEEAAEAME", "length": 169 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RJI5-1", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "gene_name": "POP5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRFKHRYLLCEVVSEDPRCRLNLEDRVLGGLVRDTIARVHGTFGAAASSIGFAVRYLNAYTGIVLLRCRKEFYRLVWSALPFITYLENKGHRYPCFFNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTRSCLLEEESTGEELSDSGGEEAAETME", "length": 170 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HI56-1", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "gene_name": "Pop5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRFKHRYLLCELVSEDARCRLSLDDRVLGGLVRDTIARVHGTFGAAACSVGFAVRYLNAYTGVVLLRCRKDFYQLVWSALPFITYLENKGHRYPCFFNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIRKSVSRSCLLEKESAEELSDSAGEEAVEIVE", "length": 169 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5BJI6-1", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "gene_name": "pop5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVRFKSRYLLCELCVSEPSSLHLFEDKVVYQALRGAVNRAHGDYGAAIFNITLGVLVKYLNAHTGVVLIRCRKAHYRLVWSSLPFITFLENRGQKVRCFFNCIHVGGTIRTSQKFLIKYNRQQLQRMLLDCKTDAEKQDVRKAILSCSLNLIKGEETDGSDDDGDEEDT", "length": 169 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6AWV1-1", "protein_name": "Probable ribonuclease P/MRP protein subunit POP5", "gene_name": "EMB1687", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVGFKNRYMLMEVFLDPDKDLLGEGTPIILTQFNLSKAIKDSILVNFGECGLGSSLGSFQVKYVNPITKLCIVRSSREEHRQVWLAITLVKSIGNCPVILNLLDISGCIRACRDTALKCDKEKFEQCSKSLSEEEIRQMNTSLEKIKLLEN", "length": 151 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q969H6-1", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "gene_name": "POP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRFKHRYLLCELVSDDPRCRLSLDDRVLSSLVRDTIARVHGTFGAAACSIGFAVRYLNAYTGIVLLRCRKEFYQLVWSALPFITYLENKGHRYPCFFNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTRSCLLEEEEESGEEAAEAME", "length": 163 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DB28-1", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "gene_name": "Pop5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRFKHRYLLCELVSEDARCRLSLDDRVLGGLVRDTIARVHGAFGAAACSVGFAVRYLNAYTGVVLLRCRKDFYQLVWSALPFITYLENKGHRYPCFFNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIKKSVSRSCLLDREPVEELSDSAGEEVAEAME", "length": 169 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VVE0-1", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "gene_name": "Pop5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVRIKNRYIAVQIVPYTPTQSLRLNDHSLTKILLQNVEKYYGVYGLAVIEQGFRVKYINDRTKMAIIRCLHRGQRFVSSVLPLITLIGDVRAKFRTLYIGATIIQCNKFIVKHQKQFLDRTMGQITSAKERQDLFKRVMEFDMDR", "length": 145 }, "evidence": [ { "id": "G1K1B6", "url": "https://omabrowser.org/oma/group/G1K1B6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6" } ], "pmid": "" }, { "name": "ribonuclease P complex", "id": "GO:0030677", "url": 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6" } ], "pmid": "" }, { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "G1K1B6", "url": "https://www.uniprot.org/uniprotkb/G1K1B6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G1K1B6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 170, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G1K1B6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G1K1B6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N315-1", "uniprot_ac": "G3N315", "uniprot_id": "G3N315_BOVIN", "mass": { "chemical_mass": 58262.0, "monoisotopic_mass": 58262.0 }, "refseq": { "ac": "XP_024832296", "name": "signal transducing adapter molecule 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832296" }, "gene_names": [ { "name": "STAM2", "type": "recommended", "evidence": [ { "id": "G3N315", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N315" } ] }, { "name": "STAM2", "type": "synonym", "evidence": [ { "id": "XP_024832296", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832296" } ] } ], "protein_names": [ { "name": "Signal transducing adaptor molecule 2", "type": "synonym", "evidence": [ { "id": "G3N315", "database": "UniProtKB", "url": 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Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as a sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SWU8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWU8#function" }, { "database": "UniProtKB", "id": "ARBA00043869", "url": "https://www.uniprot.org/uniprotkb/ARBA00043869#function" }, { "database": "UniProtKB", "id": "G3N315", "url": "https://www.uniprot.org/uniprotkb/G3N315#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N315", "url": "https://www.uniprot.org/uniprotkb/G3N315" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STAM2", "url": "https://www.uniprot.org/uniprotkb/G3N315", "locus": { 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}, { "id": "IPR047493", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047493", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050670", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050670", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45929", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45929", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45929:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45929:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02809", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02809", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-182971", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-182971", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6807004", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807004", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-917729", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-917729", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024832296", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832296", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SWU8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWU8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N315", "url": "https://www.uniprot.org/uniprotkb/G3N315", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N315-1", "url": "https://www.uniprot.org/uniprotkb/G3N315-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFTANPFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGITFPPSGSQTVSAAAKNGTSSNKNKEDEDIAKAIELSLQEQKQQHTETKSLYPSAEIQSNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTCNLNIESEAAAVDKLNIIDDEEEEIKKSEPEPVYIDEDKMDRALQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLMNEAPVYAVYSKIHHPAHYPTSSAGVPIQTYPVQPHGGNYMGQSIHQVTVAQSYSLGPDQIGPLRSLPPTVNSSVTTQPAQTPYLSTGQDTISNPTYMNQNSNLQSAPGAAAYTQQMGMSVDMSSYQNATSNLPQLAGFPVAVPAHSVAQQQTNYHQQQPLL", "length": 526, "header": "tr|G3N315-1|G3N315_BOVIN Isoform 1 of Signal transducing adaptor molecule 2 OS=Bos taurus OX=9913 GN=STAM2 PE=3 SV=3 CANONICAL=G3N315-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SWU8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWU8/entry", "sequence": { "sequence": "MPLFTANPFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGITFPPSGSQTVSAAAKNGTSSNKNKEDEDIAKAIELSLQEQKQQHTETKSLYPSAEIQSNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTCNLNIESEAAAVDKLNIIDDEEEEIKKSEPEPVYIDEDKMDRALQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLMNEAPVYAVYSKIHHPAHYPTSSAGVPIQTYPVQPHGGNYMGQSIHQVTVAQSYSLGPDQIGPLRSLPPTVNSSVTTQPAQTPYLRWHSGKESTFQAGNAETHRFDPWIRKLPWRRKWQRTPVFLPGKFHGQKSQVGSSP", "length": 504, "header": "tr|A0AAA9SWU8-1|G3N315_BOVIN Computationally mapped isoform of Signal transducing adaptor molecule 2 OS=Bos taurus OX=9913 GN=STAM2 PE=3 SV=1 CANONICAL=G3N315-1" }, "locus": { "chromosome": "2", "start_pos": 44064134, "end_pos": 44006796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134561.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134561.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090948.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090948.1" } ] } }, { "isoform_ac": "G3N315-1", "url": "https://www.uniprot.org/uniprotkb/G3N315/entry", "sequence": { "sequence": "MPLFTANPFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGITFPPSGSQTVSAAAKNGTSSNKNKEDEDIAKAIELSLQEQKQQHTETKSLYPSAEIQSNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVTCNLNIESEAAAVDKLNIIDDEEEEIKKSEPEPVYIDEDKMDRALQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALELYNKLMNEAPVYAVYSKIHHPAHYPTSSAGVPIQTYPVQPHGGNYMGQSIHQVTVAQSYSLGPDQIGPLRSLPPTVNSSVTTQPAQTPYLSTGQDTISNPTYMNQNSNLQSAPGAAAYTQQMGMSVDMSSYQNATSNLPQLAGFPVAVPAHSVAQQQTNYHQQQPLL", "length": 526, "header": "tr|G3N315-1|G3N315_BOVIN Isoform 1 of Signal transducing adaptor molecule 2 OS=Bos taurus OX=9913 GN=STAM2 PE=3 SV=3 CANONICAL=G3N315-1" }, "locus": { "chromosome": "2", "start_pos": 44053589, "end_pos": 44006796, "strand": "-", "evidence": [ { "database": "Ensembl 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] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "type": "recommended", "evidence": [ { "id": "F6RQC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQC9/entry#names_and_taxonomy" } ] }, { "name": "Adenylate cyclase-inhibiting G alpha protein", "type": "synonym", "evidence": [ { "id": "F6RQC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQC9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RQC9", "url": "https://www.uniprot.org/uniprotkb/F6RQC9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GNAI2", "url": "https://www.uniprot.org/uniprotkb/F6RQC9", "locus": { "chromosome": "22", "start_pos": 50099986, "end_pos": 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RSI9-1", "uniprot_ac": "F6RSI9", "uniprot_id": "F6RSI9_BOVIN", "mass": { "chemical_mass": 68632.0, "monoisotopic_mass": 68632.0 }, "refseq": {}, "gene_names": [ { "name": "DONSON", "type": "recommended", "evidence": [ { "id": "F6RSI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ] } ], "protein_names": [ { "name": "DNA replication fork stabilization factor DONSON", "type": "synonym", "evidence": [ { "id": "F6RSI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RSI9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DONSON", "url": "https://www.uniprot.org/uniprotkb/F6RSI9", "locus": { "chromosome": "1", "start_pos": 1954029, "end_pos": 1943576, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000035175", "url": "https://www.ensembl.org/id/ENSBTAG00000035175" } ] } } ], "crossref": [ { "id": "F6RSI9", "url": "https://alphafold.ebi.ac.uk/entry/F6RSI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035175", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035175", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR024861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WCLKTRV", "url": "https://omabrowser.org/oma/group/WCLKTRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RSI9", "url": "https://www.orthodb.org/?gene=F6RSI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12972:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12972:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SYY3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYY3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RSI9-1", "url": "https://www.uniprot.org/uniprotkb/F6RSI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWMTRANAPPRTRRERLGDGPARGPHRARAMSGSGAGSRGGGARTRGNLLPGCPPRPPPGVMDLSVPGYSPSFKRPPETLRLRRKRGRSLGAAERPEPATRRAARAAGLPLRPFPAAGRGGGGGPAGARRNPFARLDNRPRAASEPPEGPPRGQQEAPGRFLDSNQENDLLWEEKVPERTAITELHQTPHVSFSESDIPPSESTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGIIQHCRATEVTLPQSIQDPKLSTELRCAFQRSLIYWLHPALSWLPLFPRIGADRKMAGKTTPWSNDETLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTILFRAAGLAGDDVITALISPTTRGIREAMKNEGIEFSLPLIKENGPEKRKASGTGLRHGEEQAISDEDEEESFSWLEEMGVQDKIKKPDVLSIKLRKEIHEVQMDHRPESVVLVKGMNTFTLLNFLINCKSLIATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRNQFSLEITGPIMPHSLHSVTMLLQSSQNGSFSAGLYTHEPTAVFNICPPKDNVLDKEAVHEELANCGLHPKTLDHLCRTPVLGKLSLRHVEMSDYIYNWRS", "length": 620, "header": "tr|F6RSI9-1|F6RSI9_BOVIN Isoform 1 of DNA replication fork stabilization factor DONSON OS=Bos taurus OX=9913 GN=DONSON PE=3 SV=1 CANONICAL=F6RSI9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYY3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYY3/entry", "sequence": { "sequence": "MDLSVPGYSPSFKRPPETLRLRRKRGRSLGAAERPEPATRRAARAAGLPLRPFPAAGRGGGGGPAGARRNPFARLDNRPRAASEPPEGPPRGQQEAPGRFLDSNQENDLLWEEKVPERTAITELHQTPHVSFSESDIPPSESTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGIIQHCRATEVTLPQSIQDPKLSTELRCAFQRSLIYWLHPALSWLPLFPRIGADRKMAGKTTPWSNDETLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTILFRAAGLAGDDVITALISPTTRGIREAMKNEGIEFSLPLIKENGPEKRKASGTGLRHGEEQAISDEDEEESFSWLEEMGVQDKIKKPDVLSIKLRKEIHEVQMDHRPESVVLVKGMNTFTLLNFLINCKSLIATSGPQAGLPPTLLSPVAFRGATMQMLKEAVHEELANCGLHPKTLDHLCRTPVLGKLSLRHVEMSDYIYNWRS", "length": 487, "header": "tr|A0AAA9SYY3-1|F6RSI9_BOVIN Computationally mapped isoform of DNA replication fork stabilization factor DONSON OS=Bos taurus OX=9913 GN=DONSON PE=3 SV=1 CANONICAL=F6RSI9-1" }, "locus": { "chromosome": "1", "start_pos": 1953364, "end_pos": 1943961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121582.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121582.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089492.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089492.1" } ] } }, { "isoform_ac": "F6RSI9-1", "url": "https://www.uniprot.org/uniprotkb/F6RSI9/entry", "sequence": { "sequence": "MAWMTRANAPPRTRRERLGDGPARGPHRARAMSGSGAGSRGGGARTRGNLLPGCPPRPPPGVMDLSVPGYSPSFKRPPETLRLRRKRGRSLGAAERPEPATRRAARAAGLPLRPFPAAGRGGGGGPAGARRNPFARLDNRPRAASEPPEGPPRGQQEAPGRFLDSNQENDLLWEEKVPERTAITELHQTPHVSFSESDIPPSESTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGIIQHCRATEVTLPQSIQDPKLSTELRCAFQRSLIYWLHPALSWLPLFPRIGADRKMAGKTTPWSNDETLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTILFRAAGLAGDDVITALISPTTRGIREAMKNEGIEFSLPLIKENGPEKRKASGTGLRHGEEQAISDEDEEESFSWLEEMGVQDKIKKPDVLSIKLRKEIHEVQMDHRPESVVLVKGMNTFTLLNFLINCKSLIATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRNQFSLEITGPIMPHSLHSVTMLLQSSQNGSFSAGLYTHEPTAVFNICPPKDNVLDKEAVHEELANCGLHPKTLDHLCRTPVLGKLSLRHVEMSDYIYNWRS", "length": 620, "header": "tr|F6RSI9-1|F6RSI9_BOVIN Isoform 1 of DNA replication fork stabilization factor DONSON OS=Bos taurus OX=9913 GN=DONSON PE=3 SV=1 CANONICAL=F6RSI9-1" }, "locus": { "chromosome": "1", "start_pos": 1953364, "end_pos": 1943775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049667.4", "url": "https://www.ensembl.org/id/ENSBTAT00000049667.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046527.3", "url": "https://www.ensembl.org/id/ENSBTAP00000046527.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BJG1-1", "protein_name": "DNA replication fork stabilization factor DONSON", "gene_name": "DONSON", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALSVPGYSPSFKRPPETLRLRRKRGRSLGAAPPPKERPEQTTRRAALAAGLPLRPFPAAASRGGGAPAAARRNPFARLDNRPRAASEPPDGPPRSQQEAPGPRLDSNQENDLLWEEKFSERRAISEFLQIPHVSFSESDIPSSESTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGVIQHCRATEVTLPQSIQDPKLCTELRCAFQQSLIYWIHPAFPWLPLFPRIGADRKMAGKANPWSNDETLQHNLLSDWSVSLTSLYNLLKTKLCPYFYVCTYQFTILFRAAGLAGNDVMTALISPTTRGIREAMKTEGIEFSLPLIKENGHEKKEASGTGLGHGEGQAVSDEDEEESFSWLEEMGVQDKIKKPDVLSIKLRKEKHEVQMDHRPESVVLVKGMNTFTLLNFLINCKSLVASSGPQAGLPPTLLSPIAFRGATMQMLKARSVNVKTQALSGYKDQFSLEITGPVMPHSLHSVTMLLKSSQSGSFSAGLYTHEPTAVFNTCLPTDKVLDREAVLEELSNCGLHPKTLDHLSQTPVLGKSSLRHVEMSDCMYNWRS", "length": 562 }, "evidence": [ { "id": "F6RSI9", "url": "https://omabrowser.org/oma/group/F6RSI9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YL29-1", "protein_name": "DNA replication fork stabilization factor DONSON", "gene_name": "DONSON", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDATVPGYSPGFKKPPATLRLKRKRPRRSEPAAPQPCGAAPRAPSAPARRNPFSSLDNAPRQPGRRHQGEPAPPGGGPASAAPFWQFLESAGEDEPARSVGLSEGTNVLALPEDLHLPVPTPTVPTSPKHEFPADWSIKTRLLFTSSQPFTWAEHLKAQEEAQGFAQHCRAAEINLPQSVQEPKLSTELRCAFQQSLVYWLHPSLPWLQLFPRIGADRKIAGKACPWAQDEALQQALMSDWSVSFTSLYNLLKAKLCPYFYVCTYQFTVLFRAAGLAGSDVITAVLSPTTRGLREAMRNEGIEFSLPLVEESRSKKQKNSEGNLETEVAHGPEVDRSPEDGKEAAPSDDDDDGFSWLEEMGVQDKVKKPDAISIKLRKEKHEVQVDHRPESLAVVKGTNTFTLLNFLINCKSLVAVAGPQAGLPPTLLSPVAFRGGTMQTLKARSMNAKARVRLAYEDIFSLEIVGPVLPHSLHSLTMLLQSAQQGAFSAVLYTYEPTAVFNTHLDNASAALKKETISKDLLKCGLHSKTLDQLSQVPTLGKSSLRSLEMKDYAYAWKS", "length": 559 }, "evidence": [ { "id": "F6RSI9", "url": "https://omabrowser.org/oma/group/F6RSI9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PSU2-1", "protein_name": "DNA replication fork stabilization factor DONSON", "gene_name": "Donson", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVSVPGYSPSFKRPPEVVRLRRKRPRDHGTAVSSALPEPALRRAALAAGLPLRPFPTAGGRGGATTTIARRNPFARLDNRPRVADEAPEEPLRGPQGAPGPLLDSNGENNLLWEEASHERTVTELSQSQQVTLSESDTWSSDGTELPVDWSIKTRLLFTSSQPFSWAEHLKAQEEAQGLVQHCRATEVTLPQSIPDPKLSTVLRCAFQQTLVYWLHPAFSWLPLFPRIGADRKMAAKTSPWSTDESLQHALMSDWSVSFTSLYNLLKTKLCPYFYVCSYQFTVLFRAAGLAGSSVITALITPTTRGLREAMKSEGIEFSLPLLEESGHKEKVREPSLESEEEQAVSDEDEEESLSWLEEIGVQDQIKKPDLISVKLRKEKHEVQMDHRPESVVLVKGLNTFKLLNFLINCKSLVATSGAQAGLPPTLLSPVAFRGASMQMLKARSINVKTQALFGYRDKFSLEITGPVMPHALHSVAMLLRSSQRGSFSAGLYAHEPTAVFNVGLPLDKELDRKGAHKDLANCGLHPKTLEQLSQMPVLGKSSLRNVEMSDYIVNWRS", "length": 559 }, "evidence": [ { "id": "F6RSI9", "url": "https://omabrowser.org/oma/group/F6RSI9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NYP3-1", "protein_name": "Protein downstream neighbor of Son", "gene_name": "DONSON", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALSVPGYSPGFRKPPEVVRLRRKRARSRGAAASPPRELTEPAARRAALVAGLPLRPFPAAGGRGGGSGGGPAAARRNPFARLDNRPRVAAEPPDGPAREQPEAPVPFLDSNQENDLLWEEKFPERTTVTELPQTSHVSFSEPDIPSSKSTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGLVQHCRATEVTLPKSIQDPKLSSELRCTFQQSLIYWLHPALSWLPLFPRIGADRKMAGKTSPWSNDATLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTVLFRAAGLAGSDLITALISPTTRGLREAMRNEGIEFSLPLIKESGHKKETASGTSLGYGEEQAISDEDEEESFSWLEEMGVQDKIKKPDILSIKLRKEKHEVQMDHRPESVVLVKGINTFTLLNFLINSKSLVATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRDQFSLEITGPIMPHSLHSLTMLLKSSQSGSFSAVLYPHEPTAVFNICLQMDKVLDMEVVHKELTNCGLHPNTLEQLSQIPLLGKSSLRNVVLRDYIYNWRS", "length": 566 }, "evidence": [ { "id": "F6RSI9", "url": "https://omabrowser.org/oma/group/F6RSI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXP4-1", "protein_name": "Protein downstream neighbor of Son", "gene_name": "Donson", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVSVPGYSPSFKRPPETVRLRRKRSRDHGAAVPASLPEPAPRRAALAAGLPLRPFPTAGGRGGAAATIARRNPFARLDNRPRVSDEASEEPLRGPQGASGPLLDSNEENNLLWEDTSSHERTGTELSQSQRVSLSESDTWSSDGTELPVDWSIKTRLLFTSSQPFSWADHLKAQEEAQGLVQHCRATEVTLPQSIQDPKLSTALRCAFQQALVYWLHPAFSWLPLFPRIGADRKMAAKTSPWSADETLQHALMSDWSVSFTSLYNLLKTKLCPYFYVCSYQFTVLFRAAGLAGSSVITALISPTTRGLREAMRNEGIEFSLPLLEEIGHKKKVRDPSLESEEEQAVSDEDEEESFSWLEEIGVQDQIKKPDVISIKLRKEKHEVQMDHRPESVVLVKGLNTFKLLNFLINCKSLVATSGAQAGLPPTLLSPIAFRGASMQMLKARSSNVKTQALSGYRDKFSLDITGPVMPHALHSMSMLLRSSQRGSFSAGLYAHEPTAVFNVGLSLDKELDRKVAREDLANCGLHPKTLEQLSQRPVLGKSSLRSVEMSDYILSWRS", "length": 560 }, "evidence": [ { "id": "F6RSI9", "url": "https://omabrowser.org/oma/group/F6RSI9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VNA8-1", "protein_name": "Protein downstream neighbor of son homolog", "gene_name": "hd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTEASVASKWTRPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKSKLLEAKLAQKRKNPFAKSTADAKKLRVDPQLADLEPVVTASSCFVRETPTRPAPAKFVLQKYDPQAFAKLFQHPQINAEDEDDAELAARQKHTAHLPVDWSLKTRARFFCPTELPAIQLKTSQLASGLTSFVRCMDPQRTESTLDISDATRFNQCNYYWQHPHLPWLTLYPRTAKENVGVVVGERERKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRPESHALVTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQEDEDDDEDWLESLGVDERELRRIQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNAKSAISTVGRLAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGVDYFSIDIKGLILPTFLPSVAELLSETRQMFSSTLASSINTLAFSKATQKLLETPETPQSDAEGEDAAGQVFGEQNLSECGLLPAVVGSICRTGQHAVGLLERVCYQRDEGYAWS", "length": 568 }, "evidence": [ { "id": "F6RSI9", "url": "https://omabrowser.org/oma/group/F6RSI9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ], "pmid": "" }, { "name": "replisome", "id": "GO:0030894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030894", "evidence": [ { "database": "UniProtKB", "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ], "pmid": "" }, { "name": "nuclear DNA replication", "id": "GO:0033260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033260", "evidence": [ { "database": "UniProtKB", "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "F6RSI9", "url": "https://www.uniprot.org/uniprotkb/F6RSI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RSI9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 620, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RSI9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RSI9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 547, "end_pos": 549 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MWS7-1", "uniprot_ac": "G3MWS7", "uniprot_id": "G3MWS7_BOVIN", "mass": { "chemical_mass": 53633.0, "monoisotopic_mass": 53633.0 }, "refseq": { "ac": "XP_024856895", "name": "transcription factor-like 5 protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856895" }, "gene_names": [ { "name": "TCFL5", "type": "recommended", "evidence": [ { "id": "G3MWS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWS7" } ] }, { "name": "TCFL5", "type": "synonym", "evidence": [ { "id": "XP_024856895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856895" } ] } ], "protein_names": [ { "name": "Transcription factor like 5", "type": "synonym", "evidence": [ { "id": "G3MWS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWS7/entry#names_and_taxonomy" } ] }, { "name": "transcription factor-like 5 protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024856895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856895" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWS7", "url": "https://www.uniprot.org/uniprotkb/G3MWS7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TCFL5", "url": "https://www.uniprot.org/uniprotkb/G3MWS7", "locus": { "chromosome": "13", "start_pos": 54545735, "end_pos": 54528042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046520", "url": "https://www.ensembl.org/id/ENSBTAG00000046520" } ] } } ], "crossref": [ { "id": "G3MWS7", "url": "https://alphafold.ebi.ac.uk/entry/G3MWS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046520", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18909", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18909", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513750", "url": "https://www.ncbi.nlm.nih.gov/gene/513750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MWS7", "url": "https://www.orthodb.org/?gene=G3MWS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15402", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15402", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15402:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15402:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024856895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024856895", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T061", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T061", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T061-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T061-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWS7", "url": "https://www.uniprot.org/uniprotkb/G3MWS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWS7-1", "url": "https://www.uniprot.org/uniprotkb/G3MWS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSBTAP00000089777.1" } ] } }, { "isoform_ac": "G3MWS7-1", "url": "https://www.uniprot.org/uniprotkb/G3MWS7/entry", "sequence": { "sequence": "MSGPGPREPPQAGGPAGPEGADATLGEAGLSFTTTDLSLVEMTEIEYTQLQHILYSHMEAAAADGELETRLNSAFLAAAAPGAAAGSFAAAGGAAAAAAGGAPPVYPVLCPPTLADGGFAGANQCLGHIDFQELRMMLLSEAGAAPAAEKTPGADGPGPGAPRPKAPDGAGKENAEGAPEARAKSAVRVRLEDRFNSIPAETPPAPRGAEPPEPGVALNNLVTLIRHPSELMNVPLHQQQNKCTTLVKNKTTAATTALQFTYPLFTTNACATSGNSNISQTQSSSNSCSILETAKHQDIGLPRAFSFCYQQEIESTKQTLGSRNKALPEQVWIKVGEALCKQAISKRNRSRIRQLDTNVERRALGEIQNVGEGSTAAQGAWQSAESSQATLGEQTQSGPQGGRSQRRERHNRMERDRRRRIRICCDELNLLVPFCNAETDKATTLQWTTAFLKYIQERHGDSLKKEFESVFCGKTGRRLKLTRPDSLVTCPAQESLQSSPAVEIK", "length": 505, "header": "tr|G3MWS7-1|G3MWS7_BOVIN Isoform 1 of Transcription factor like 5 OS=Bos taurus OX=9913 GN=TCFL5 PE=4 SV=3 CANONICAL=G3MWS7-1" }, "locus": { "chromosome": "13", "start_pos": 54544731, "end_pos": 54528141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"evidence": [ { "database": "UniProtKB", "id": "G3MWS7", "url": "https://www.uniprot.org/uniprotkb/G3MWS7" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "G3MWS7", "url": "https://www.uniprot.org/uniprotkb/G3MWS7" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G3MWS7", "url": "https://www.uniprot.org/uniprotkb/G3MWS7" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "G3MWS7", "url": "https://www.uniprot.org/uniprotkb/G3MWS7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { 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"Protein Classification" ] }, { "id": "PTHR47633:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47633:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T619", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T619", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T619-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T619-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U101", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U101", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U101-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U101-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N022-1", "url": "https://www.uniprot.org/uniprotkb/G3N022-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAAAAVAGAPVFLRPLKDAAVSAGSDVRLRVVVSGTPQPSLSWFRDGQRLPPPAPEPSCLWLRSCGPRDAGVYSCRAQNELGQASCEAVLTVLEVGDSETGEDDISDGQGTQRLELRDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSRAGTRRLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLHKEEPDLQPQPASEAPRRPALPPPSKSALLPPPSPRVGKRPPPGAGGQPLATPTPPHRRSREPVPPEDATAEEKRGKKSKSSGPSLAGTAESRPQTPLSEASGRQSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGGPWGTPRASQEELRSPAGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPPREPGEPPLFSQPSTPKTPRALSPAAAQPPPASVAEKPGDEPGRPRGRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPTSEPPETRTKAPPGRKREPPPQAVRFLPWATPGQEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGAWDRRGARSQGRGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNAVVAPGVDVLLKCIVTANPPPQVSWQKDGSPLRSDGRLLIRAEGERHTLLLREARAADAGSYAATATNELGQARCAATLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRAPTMKLSPGQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVTMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEDGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGSPPPSVTWTHFGHPVEESENVRLRQDGGLHSLHIAHVGSEDEGLYAVSAANTHGQAHCSAQLYVEEPRTAATGPSSKLEKMPSIPEEPEQGELERLSMPDFLRPLQDLDVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMITLAWNPPRSLDMAIDPDALTYTVQHQVLGSDQWTALVTGLRQPGWAATGLRKGVQHVFRVLSTTIKSSSKPSPPSEPTQLLERGPPLEEAPAVLDKPDVVYVVEGQPTSVTVTFNHVEAQVVWRSCRGALLEARPGVFELSQPDDDQYSLRICRVSRRDLGALTCTARNRHGTQACSVTLELAEAPRFESIMEDVEVGAGETARFAVVVDGKPLPDIMWYKDEALLTESNHVSFVYEENECSLVVLSAGAQDGGVYTCTARNLAGEVSCKAELAVHSAQTAMEVEGIGEDEEQRGRRLSDFYDIQQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASAWREARLLARLQHDCILYFHEAFERRRGLVIVTELCTEELLERMARKPTVCESEIRAYMRQVLEGICYLHENHVLHLDVKPENLLVWDGVEGEEQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQTPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVRDRLRPTAEETLEHPWFKAQAKGAVVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAVPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGALEAGAATPMDWQEQGKAPSQDQEAPSPQALPSPGQESPSGPSPRRAELRRGSSAESALPRAGPREPGRGLHKAASVELPQRRSPSPGATRLTRGGLGEGEYAQRLQALRQRLLRGGPDDGKVSGLRGPLLESLGGRARDPRLARAASSEAAPHHQHPPEARGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARKLQESPSLSALSEAQPPSPVRPSAAKPSTPKSSEPLVGTPSEAAQPPAPQPAREKAPESTPEPARGPKPTQPPTALQTLAPPLTPYAQIMQSLQLPGQAQGPPQGAVVSPTSRSPASRLEPKPHPAVFSRVASPPPGASEKRLLPGAGATPGPAEKARVPAVPRRPGSSLSSSIENLESEAVFEAKFKRSRESPLSRGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPGLVRRLSLSLSQRLRRTPPAQRHPAWEPRGGDGESSEGGSSARGSPVLTVRRRLSSTLERLSSRLQRSGSSEDSGGASGRSTPLFGRLRRATSESESLRRLDLAQNQLAAQAGAATPSAESLGSEASATSGSSAPAESRSRLRWGLSRLRKDKRLSQPNLSGSVQEDLGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKQSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARTPGKLAPPEVPQTYQDTALVLWKPGDSKAPCTYTLERRVDGESSWHPVSSGIPDCYYNVTHLPVGMAVRFRVACANRAGQGPFSNPSEKVLVRGVQDSSALPSAAHRDAPVTSGPARAPPPDAPTSLAPPLSPSPAPAPPGPQAAPLGPSSSPAPPSQALSSLKAVGPPPQTPPRKHRGLQAAQQVEPTPPSAQDSPSEPKSSVPDTGTPIPASAPQVVKTASSSMPLYMVTSFVSAPPAPEPPAPEPPPEPTKVTVRSLSPAKEVVGSPGGGPPRAPKPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRQVLQEYEVLRTLHHERLMALHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGRHVLHLDIKPDNLLLAPDNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSVQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP", "length": 3280, "header": "tr|G3N022-1|G3N022_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SPEG PE=3 SV=2 CANONICAL=G3N022-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T619-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T619/entry", "sequence": { "sequence": "MKKLWVKKRFQKTGHSRRAFGRLTHDSETGEDDISDGQGTQRLELRDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSRAGTRRLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLHKEEPDLQPQPASEAPRRPALPPPSKSALLPPPSPRVGKRPPPGAGGQPLATPTPPHRRSREPVPPEDATAEEKRGKKSKSSGPSLAGTAESRPQTPLSEASGRQSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGGPWGTPRASQEELRSPAGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSREPGEPPLFSQPSTPKTPRALSPAAAQPPPASVAEKPGDEPGRPRGRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPTSEPPETRTKAPPGRKREPPPQAVRFLPWATPGQEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGAWDRRGARSQGRGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNAVVAPGVDVLLKCIVTANPPPQVSWQKDGSPLRSDGRLLIRAEGERHTLLLREARAADAGSYAATATNELGQARCAATLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRAPTMKLSPGQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVTMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEDGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRGE", "length": 858, "header": "tr|A0AAA9T619-1|G3N022_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SPEG PE=3 SV=1 CANONICAL=G3N022-1" }, "locus": { "chromosome": "2", "start_pos": 107395874, "end_pos": 107372815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101297.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101297.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094193.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094193.1" } ] } }, { "isoform_ac": "A0AAA9U101-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U101/entry", "sequence": { "sequence": "MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAAAAVAGAPVFLRPLKDAAVSAGSDVRLRVVVSGTPQPSLSWFRDGQRLPPPAPEPSCLWLRSCGPRDAGVYSCRAQNELGQASCEAVLTVLEVGDSETGEDDISDGQGTQRLELRDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSRAGTRRLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLHKEEPDLQPQPASEAPRRPALPPPSKSALLPPPSPRVGKRPPPGAGGQPLATPTPPHRRSREPVPPEDATAEEKRGKKSKSSGPSLAGTAESRPQTPLSEASGRQSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGGPWGTPRASQEELRSPAGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSREPGEPPLFSQPSTPKTPRALSPAAAQPPPASVAEKPGDEPGRPRGRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPTSEPPETRTKAPPGRKREPPPQAVRFLPWATPGQEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGAWDRRGARSQGRGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNAVVAPGVDVLLKCIVTANPPPQVSWQKDGSPLRSDGRLLIRAEGERHTLLLREARAADAGSYAATATNELGQARCAATLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRAPTMKLSPGQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVTMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEDGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGSPPPSVTWTHFGHPVEESENVRLRQDGGLHSLHIAHVGSEDEGLYAVSAANTHGQAHCSAQLYVEEPRTAATGPSSKLEKMPSIPEEPEQGELERLSMPDFLRPLQDLDVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMITLAWNPPRSLDMAIDPDALTYTVQHQVLGSDQWTALVTGLRQPGWAATGLRKGVQHVFRVLSTTIKSSSKPSPPSEPTQLLERGPPLEEAPAVLDKPDVVYVVEGQPTSVTVTFNHVEAQVVWRSCRGALLEARPGVFELSQPDDDQYSLRICRVSRRDLGALTCTARNRHGTQACSVTLELAEAPRFESIMEDVEVGAGETARFAVVVDGKPLPDIMWYKDEALLTESNHVSFVYEENECSLVVLSAGAQDGGVYTCTARNLAGEVSCKAELAVHSAQTAMEVEGIGEDEEQRGRRLSDFYDIQQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASAWREARLLARLQHDCILYFHEAFERRRGLVIVTELCTEELLERMARKPTVCESEIRAYMRQVLEGICYLHENHVLHLDVKPENLLVWDGVEGEEQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQTPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVRDRLRPTAEETLEHPWFKAQAKGAVVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAVPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGALEAGAATPMDWQEQGKAPSQDQEAPSPQALPSPGQESPSGPSPRRAELRRGSSAESALPRAGPREPGRGLHKAASVELPQRRSPSPGATRLTRGGLGEGEYAQRLQALRQRLLRGGPDDGKVSGLRGPLLESLGGRARDPRLARAASSEAAPHHQHPPEARGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARKLQESPSLSALSEAQPPSPVRPSAAKPSTPKSSEPLVGTPSEAAQPPAPQPAREKAPESTPEPARGPKPTQPPTALQTLAPPLTPYAQIMQSLQLPGQAQGPPQGAVVSPTEPKPHPAVFSRVASPPPGASEKRLLPGAGATPGPAEKARVPAVPRRPGSSLSSSIENLESEAVFEAKFKRSRESPLSRGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPGLVRRLSLSLSQRLRRTPPAQRHPAWEPRGGDGESSEGGSSARGSPVLTVRRRLSSTLERLSSRLQRSGSSEDSGGASGRSTPLFGRLRRATSESESLRRLDLAQNQLAAQAGAATPSAESLGSEASATSGSSAPAESRSRLRWGLSRLRKDKRLSQPNLSGSVQEDLGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKQSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARTPGKLAPPEVPQTYQDTALVLWKPGDSKAPCTYTLERRVDGESSWHPVSSGIPDCYYNVTHLPVGMAVRFRVACANRAGQGPFSNPSEKVLVRGVQDSSALPSAAHRDAPVTSGPARAPPPDAPTSLAPPLSPSPAPAPPGPQAAPLGPSSSPAPPSQALSSLKAVGPPPQTPPRKHRGLQAAQQVEPTPPSAQDSPSEPKSSVPDTGTPIPASAPQVVKTASSSMPLYMVTSFVSAPPAPEPPAPEPPPEPTKVTVRSLSPAKEVVGSPGGGPPRAPKPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRQVLQEYEVLRTLHHERLMALHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGRHVLHLDIKPDNLLLAPDNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSVQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP", "length": 3272, "header": "tr|A0AAA9U101-1|G3N022_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SPEG PE=3 SV=1 CANONICAL=G3N022-1" }, "locus": { "chromosome": "2", "start_pos": 107423366, "end_pos": 107365755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135053.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135053.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103670.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103670.1" } ] } }, { "isoform_ac": "G3N022-1", "url": "https://www.uniprot.org/uniprotkb/G3N022/entry", "sequence": { "sequence": "MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAAAAVAGAPVFLRPLKDAAVSAGSDVRLRVVVSGTPQPSLSWFRDGQRLPPPAPEPSCLWLRSCGPRDAGVYSCRAQNELGQASCEAVLTVLEVGDSETGEDDISDGQGTQRLELRDDGAFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQEAGSRAGTRRLPGSPRQAQATGAGPRHLGVEPLVRASRANLVGASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLHKEEPDLQPQPASEAPRRPALPPPSKSALLPPPSPRVGKRPPPGAGGQPLATPTPPHRRSREPVPPEDATAEEKRGKKSKSSGPSLAGTAESRPQTPLSEASGRQSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSEGGGPWGTPRASQEELRSPAGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPPREPGEPPLFSQPSTPKTPRALSPAAAQPPPASVAEKPGDEPGRPRGRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPTSEPPETRTKAPPGRKREPPPQAVRFLPWATPGQEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGAWDRRGARSQGRGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNAVVAPGVDVLLKCIVTANPPPQVSWQKDGSPLRSDGRLLIRAEGERHTLLLREARAADAGSYAATATNELGQARCAATLAVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRAPTMKLSPGQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVTMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEDGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGSPPPSVTWTHFGHPVEESENVRLRQDGGLHSLHIAHVGSEDEGLYAVSAANTHGQAHCSAQLYVEEPRTAATGPSSKLEKMPSIPEEPEQGELERLSMPDFLRPLQDLDVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMITLAWNPPRSLDMAIDPDALTYTVQHQVLGSDQWTALVTGLRQPGWAATGLRKGVQHVFRVLSTTIKSSSKPSPPSEPTQLLERGPPLEEAPAVLDKPDVVYVVEGQPTSVTVTFNHVEAQVVWRSCRGALLEARPGVFELSQPDDDQYSLRICRVSRRDLGALTCTARNRHGTQACSVTLELAEAPRFESIMEDVEVGAGETARFAVVVDGKPLPDIMWYKDEALLTESNHVSFVYEENECSLVVLSAGAQDGGVYTCTARNLAGEVSCKAELAVHSAQTAMEVEGIGEDEEQRGRRLSDFYDIQQEIGRGAFSYLRRVVERSSGLEFAAKFIPSQAKPKASAWREARLLARLQHDCILYFHEAFERRRGLVIVTELCTEELLERMARKPTVCESEIRAYMRQVLEGICYLHENHVLHLDVKPENLLVWDGVEGEEQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQTPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVLVRDRLRPTAEETLEHPWFKAQAKGAVVSTDHLKLFLSRRRWQRSQISYKCHLVLRPIPELLRAPPERVWVAVPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALGALEAGAATPMDWQEQGKAPSQDQEAPSPQALPSPGQESPSGPSPRRAELRRGSSAESALPRAGPREPGRGLHKAASVELPQRRSPSPGATRLTRGGLGEGEYAQRLQALRQRLLRGGPDDGKVSGLRGPLLESLGGRARDPRLARAASSEAAPHHQHPPEARGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARKLQESPSLSALSEAQPPSPVRPSAAKPSTPKSSEPLVGTPSEAAQPPAPQPAREKAPESTPEPARGPKPTQPPTALQTLAPPLTPYAQIMQSLQLPGQAQGPPQGAVVSPTSRSPASRLEPKPHPAVFSRVASPPPGASEKRLLPGAGATPGPAEKARVPAVPRRPGSSLSSSIENLESEAVFEAKFKRSRESPLSRGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPGLVRRLSLSLSQRLRRTPPAQRHPAWEPRGGDGESSEGGSSARGSPVLTVRRRLSSTLERLSSRLQRSGSSEDSGGASGRSTPLFGRLRRATSESESLRRLDLAQNQLAAQAGAATPSAESLGSEASATSGSSAPAESRSRLRWGLSRLRKDKRLSQPNLSGSVQEDLGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKQSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARTPGKLAPPEVPQTYQDTALVLWKPGDSKAPCTYTLERRVDGESSWHPVSSGIPDCYYNVTHLPVGMAVRFRVACANRAGQGPFSNPSEKVLVRGVQDSSALPSAAHRDAPVTSGPARAPPPDAPTSLAPPLSPSPAPAPPGPQAAPLGPSSSPAPPSQALSSLKAVGPPPQTPPRKHRGLQAAQQVEPTPPSAQDSPSEPKSSVPDTGTPIPASAPQVVKTASSSMPLYMVTSFVSAPPAPEPPAPEPPPEPTKVTVRSLSPAKEVVGSPGGGPPRAPKPEGTTLRQGPPQKPYTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKRQVLQEYEVLRTLHHERLMALHEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGRHVLHLDIKPDNLLLAPDNALKIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGDPIGSATDIWGAGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSVQDCLAHPWLQDAYLMKLRRQTLTFTTNRLKEFLGEQRRRRAEAATRHKVLLRSYPGSP", "length": 3280, "header": "tr|G3N022-1|G3N022_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SPEG PE=3 SV=2 CANONICAL=G3N022-1" }, "locus": { "chromosome": "2", "start_pos": 107423366, "end_pos": 107365755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066051.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066051.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055177.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055177.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2309, "start_aa": "Thr", "end_pos": 2309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2309", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2528, "start_aa": "Thr", "end_pos": 2528, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2528", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2874, "start_aa": "Thr", "end_pos": 2874, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2874", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 333, "start_aa": "Thr", "end_pos": 333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 645, "start_aa": "Thr", "end_pos": 645, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr645", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 995, "start_aa": "Thr", "end_pos": 995, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr995", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YYZ3-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "SPEG", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"length": 3424 }, "evidence": [ { "id": "G3N022", "url": "https://omabrowser.org/oma/group/G3N022/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ], "pmid": "" }, { "name": "muscle structure development", "id": "GO:0061061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061061", "evidence": [ { "database": "UniProtKB", "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ], "pmid": "" }, { "name": "muscle cell differentiation", "id": "GO:0042692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042692", "evidence": [ { "database": "UniProtKB", "id": "G3N022", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1770, "end_pos": 1772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2571, "end_pos": 2573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2743, "end_pos": 2745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2999, "end_pos": 3001, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3199, "end_pos": 3201, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", 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"P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] } ] }, { "uniprot_ac": "A0A3Q1M1Z0", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] } ] }, { "uniprot_ac": "A0A3Q1M2U5", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] } ] }, { "uniprot_ac": "A0A3Q1M334", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] } ] }, { "uniprot_ac": "A0A3Q1M4N6", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] } ] }, { "uniprot_ac": "A0A3Q1M4X3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] } ] }, { "uniprot_ac": "A0A3Q1M5T5", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] } ] }, { "uniprot_ac": "A0A3Q1M614", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] } ] }, { "uniprot_ac": "A0A3Q1M6N5", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] } ] }, { "uniprot_ac": "A0A3Q1M9F0", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] } ] }, { "uniprot_ac": "A0A3Q1M9L7", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] } ] }, { "uniprot_ac": "A0A3Q1MA37", "gene_name": "CDC42BPG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] } ] }, { "uniprot_ac": "A0A3Q1MD82", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MHH5", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 1285, "end_pos": 1382, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 124, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 1601, "end_pos": 1854, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 333, 645, 995, 2309, 2528, 2874 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1770, "end_pos": 1772 }, { "start_pos": 2571, "end_pos": 2573 }, { "start_pos": 2743, "end_pos": 2745 }, { "start_pos": 2999, "end_pos": 3001 }, { "start_pos": 3199, "end_pos": 3201 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"uniprot_canonical_ac": "G3MZ93-1", "uniprot_ac": "G3MZ93", "uniprot_id": "G3MZ93_BOVIN", "mass": { "chemical_mass": 100575.0, "monoisotopic_mass": 100575.0 }, "refseq": {}, "gene_names": [ { "name": "CFAP221", "type": "recommended", "evidence": [ { "id": "G3MZ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 221", "type": "synonym", "evidence": [ { "id": "G3MZ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CFAP221", "url": "https://www.uniprot.org/uniprotkb/G3MZ93", "locus": { "chromosome": "2", "start_pos": 71470964, "end_pos": 71339591, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000054356", "url": "https://www.ensembl.org/id/ENSBTAG00000054356" } ] } } ], "crossref": [ { "id": "G3MZ93", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ93", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000054356", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613775", "url": "https://www.ncbi.nlm.nih.gov/gene/613775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613775", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613775", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46500", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46500", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46500:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46500:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T6Z1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFT0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ93-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVKTPSREVKNAEEPFQNVSPLLLRNLVEEPKRPKEVPNHLLESKVYANLLNNKVIQAKPGILHFGGYQVEKQHQQILHLVNICDEDIHVHILPPQTKYFQIKYVKKEHRLVPGLSLRITITFSPDEWRYYYDCIRVHCKGDETLLIPIHAYPVVNTLDFPSFINLSNVLLGESKSYVIPLWCSCPVDFEFHVTVVHPHQAFTVEPTSGIIPANGKMNVTVKFTPFQYGMAQIKVQLWVSQFNSQPYECVFTGTCYPNVALKLEEFERVNNLSKKVVVPPEKAMTRVPFPQLPAKAKPPKIKEIEYHNLRFPVDLLSPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDTCEEIENHLKWQVHLGKDHMSFKFKKDIYEERQRVNNKYKLDRGDPILYEEFQRRKTEVHPKRILHDLKEKIQEFHPNFDPLINNTWVNRFRAQRRFQQAARKVLIHRRLLTMLNAVRNIQKDIIMKRFTQEGQSMAQDKSFKYHLGRVSKDASRFSVSPQEVLPFAFPSYSPPQDSNELAPGGLGPVPIKSSEIQVKQPHSFFNLQVPQLYKIKRYQPVSVQESSASYRPQKLARALRQGAEDEATTVITLPKQDSSPQLPGETSVLSIKLPEALAHAPDYDPLYIFNPSPGLFAVKHPLTYVETLIDYHLCSHPKYKFTKECHCGSSIPITQKQFLHHTDIIPGVMTWKRFQSLVFLSLPETSKTEVLPSCDSFNLVMLPVDVPAVLDALPEEDRIETVERELCEQSMDIMLTPEMIEAEFPMLDYRDTKKENFSWKQTECQTDTHESLDRRTEIKNTSVILNVPMKTAVNLVSGKYLFSWMQRIICSFLKVVINPRASLLS", "length": 871, "header": "tr|G3MZ93-1|G3MZ93_BOVIN Isoform 1 of Cilia and flagella associated protein 221 OS=Bos taurus OX=9913 GN=CFAP221 PE=4 SV=3 CANONICAL=G3MZ93-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T6Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Z1/entry", "sequence": { "sequence": "MAAVKTPSREVKNAEEPFQNVSPLLLRNLVEEPKRPKEVPNHLLESKVYANLLNNKVIQAKPGILHFGGYQVEKQHQQILHLVNICDEDIHVHILPPQTKYFQIKYVKKEHRLVPGLSLRITITFSPDEWRYYYDCIRVHCKGDETLLIPIHAYPVVNTLDFPSFINLSNVLLGESKSYVIPLWCSCPVDFEFHVTVVHPHQAFTVEPTSGIIPANGKMNVTVKFTPFQYGMAQIKVQLWVSQFNSQPYECVFTGTCYPNVALKLEEFERVNNLSKKVVVPPEKAMTRVPFPQLPAKAKPPKIKEIEYHNLRFPVDLLSPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDTCEEIENHLKWQVHLGKDHMSFKFKKDIYEERQRVNNKYKLDRGDPILYEEFQRRKTEVHPKRILHDLKEKIQEFHPNFDPLINNTWVNRFRAQRRFQQAARKVLIHRRLLTMLNAVRNIQKDIIMKRFTQEGQSMAQDKSFKYHLGRVSKDASRFSVSPQEVLPFAFPSYSPPQDSNELAPGGLGPVPIKSSEIQVKQPHSFFNLQVPQLYKIKRYQPVSVQESSASYRPQKLARALRQGAEDEATTVITLPKQDSSPQLPGETSVLSIKLPEALAHAPDYDPLYIFNPSPGLFAVKHPLTYVETLIDYHLCSHPKYKFTKECHCGSSIPITQKQFLHHTDIIPGVMTWKRFQSLVFLSLPETSKTEVLPSELCEQSMDIMLTPEMIEAEFPMLDYRDTKKEKEVKDQAQPTEKAGEKVLEEMKNLRSKALSSYLILE", "length": 806, "header": "tr|A0AAA9T6Z1-1|G3MZ93_BOVIN Computationally mapped isoform of Cilia and flagella associated protein 221 OS=Bos taurus OX=9913 GN=CFAP221 PE=4 SV=1 CANONICAL=G3MZ93-1" }, "locus": { "chromosome": "2", "start_pos": 71470024, "end_pos": 71339638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104588.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104588.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091568.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091568.1" } ] } }, { "isoform_ac": "A0AAA9TFT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFT0/entry", "sequence": { "sequence": "MAAVKTPSREVKNAEEPFQNVSPLLLRNLVEEPKRPKEVPNHLLESKVYANLLNNKVIQAKPGILHFGGYQVEKQHQQILHLVNICDEDIHVHILPPQTKYFQIKYVKKEHRLVPGLSLRITITFSPDEWRYYYDCIRVHCKGDETLLIPIHAYPVVNTLDFPSFINLSNVLLGESKSYVIPLWCSCPVDFEFHVTVVHPHQAFTVEPTSGIIPANGKMNVTVKFTPFQYGMAQIKVQLWVSQFNSQPYECVFTGTCYPNVALKLEEFERVNNLSKKVVVPPEKAMTRVPFPQLPAKAKPPKIKEIEYHNLRFPVDLLSPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDTCEEIENHLKWQVHLGKDHMSFKFKKDIYEERQRVNNKYKLDRGDPILYEEFQRRKTEVHPKRILHDLKEKIQEFHPNFDPLINNTWVNRFRAQRRFQQAARKVLIHRRLLTMLNAVRNIQKDIIMKRFTQEGQSMAQDKSFKYHLGRVSKDASRFSVSPQEVLPFAFPSYSPPQDSNELAPGGLGPVPIKSSEIQVKQPHSFFNLQVPQLYKIKRYQPVSVQESSASYRPQKLARALRQGAEDEATTVITLPKQDSSPQLPGETSVLSIKLPEALAHAPDYDPLYIFNPSPGLFAVKHPLTYVETLIDYHLCSHPKYKFTKECHCGSSIPITQKQFLHHTDIIPGVMTWKRFQSLVFLSLPETSKTEVLPSCDSFNLVMLPVDVPAVLDALPEEDRIETVERELCEQSMDIMLTPEMIEAEFPMLDYRDTKKEKEVKDQAQPTEKAGEKVLEEMKNLRSKALSSYLILE", "length": 837, "header": "tr|A0AAA9TFT0-1|G3MZ93_BOVIN Computationally mapped isoform of Cilia and flagella associated protein 221 OS=Bos taurus OX=9913 GN=CFAP221 PE=4 SV=1 CANONICAL=G3MZ93-1" }, "locus": { "chromosome": "2", "start_pos": 71470024, "end_pos": 71339638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087779.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087779.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095874.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095874.1" } ] } }, { "isoform_ac": "G3MZ93-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ93/entry", "sequence": { "sequence": "MAAVKTPSREVKNAEEPFQNVSPLLLRNLVEEPKRPKEVPNHLLESKVYANLLNNKVIQAKPGILHFGGYQVEKQHQQILHLVNICDEDIHVHILPPQTKYFQIKYVKKEHRLVPGLSLRITITFSPDEWRYYYDCIRVHCKGDETLLIPIHAYPVVNTLDFPSFINLSNVLLGESKSYVIPLWCSCPVDFEFHVTVVHPHQAFTVEPTSGIIPANGKMNVTVKFTPFQYGMAQIKVQLWVSQFNSQPYECVFTGTCYPNVALKLEEFERVNNLSKKVVVPPEKAMTRVPFPQLPAKAKPPKIKEIEYHNLRFPVDLLSPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDTCEEIENHLKWQVHLGKDHMSFKFKKDIYEERQRVNNKYKLDRGDPILYEEFQRRKTEVHPKRILHDLKEKIQEFHPNFDPLINNTWVNRFRAQRRFQQAARKVLIHRRLLTMLNAVRNIQKDIIMKRFTQEGQSMAQDKSFKYHLGRVSKDASRFSVSPQEVLPFAFPSYSPPQDSNELAPGGLGPVPIKSSEIQVKQPHSFFNLQVPQLYKIKRYQPVSVQESSASYRPQKLARALRQGAEDEATTVITLPKQDSSPQLPGETSVLSIKLPEALAHAPDYDPLYIFNPSPGLFAVKHPLTYVETLIDYHLCSHPKYKFTKECHCGSSIPITQKQFLHHTDIIPGVMTWKRFQSLVFLSLPETSKTEVLPSCDSFNLVMLPVDVPAVLDALPEEDRIETVERELCEQSMDIMLTPEMIEAEFPMLDYRDTKKENFSWKQTECQTDTHESLDRRTEIKNTSVILNVPMKTAVNLVSGKYLFSWMQRIICSFLKVVINPRASLLS", "length": 871, "header": "tr|G3MZ93-1|G3MZ93_BOVIN Isoform 1 of Cilia and flagella associated protein 221 OS=Bos taurus OX=9913 GN=CFAP221 PE=4 SV=3 CANONICAL=G3MZ93-1" }, "locus": { "chromosome": "2", "start_pos": 71468363, "end_pos": 71339638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065696.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065696.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054888.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054888.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 209, "start_aa": "Thr", "end_pos": 209, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr209", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:613775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613775", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" }, { "name": "sperm head-tail coupling apparatus", "id": "GO:0120212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120212", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "G3MZ93", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZ93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 871, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZ93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZ93" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ93" }, { "id": "PF22067", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cep192-like", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 256, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 209 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 802, "end_pos": 804 }, { "start_pos": 826, "end_pos": 828 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RVI7-1", "uniprot_ac": "F6RVI7", "uniprot_id": "F6RVI7_BOVIN", "mass": { "chemical_mass": 80114.0, "monoisotopic_mass": 80114.0 }, "refseq": {}, "gene_names": [ { "name": "MTO1", "type": "recommended", "evidence": [ { "id": "F6RVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ] } ], "protein_names": [ { "name": "5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial", "type": "recommended", "evidence": [ { "id": "F6RVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVI7/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial tRNA translation optimization 1", "type": "synonym", "evidence": [ { "id": "F6RVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVI7/entry#names_and_taxonomy" } ] }, { "name": "Protein MTO1 homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "F6RVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVI7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7#function" }, { "database": "UniProtKB", "id": "ARBA00056538", "url": "https://www.uniprot.org/uniprotkb/ARBA00056538#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTO1", "url": "https://www.uniprot.org/uniprotkb/F6RVI7", "locus": { "chromosome": "9", "start_pos": 12991396, "end_pos": 12969820, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016839", "url": "https://www.ensembl.org/id/ENSBTAG00000016839" } ] } } ], "crossref": [ { "id": "F6RVI7", "url": "https://alphafold.ebi.ac.uk/entry/F6RVI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002218", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002218", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11806", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11806", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11806:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11806:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21680", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21680", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "83279", "url": "https://www.rhea-db.org/rhea/83279", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T966", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T966", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T966-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T966-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RVI7-1", "url": "https://www.uniprot.org/uniprotkb/F6RVI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCIRGCGRRVAASLTKQHLASVRFGGDSAAPWTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKYRVSGVVLGSRFPSSGAFLGTGVVFLSVILSLTSCRADGSKVYAESVVLTTGTFLRGMIVIGLEMHPAGRLGDQPAVGLAQTLEKLGFVVGRLKTGTPPRIAKESVNFSILNKQTPDNPSIPFSFINQTVWIKPEDQLPCYLTHTNPRVDEIVLENLHLNCHVKETTRGPRYCPSIESKVLRFPNRVHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLENAKMIQPGYGVQYDYMDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVRHKPPFVISRTEGYIGVLIDDLTTLGTNEPYRMFTSRAEFRLSLRPDNADSRLTFRGYKEAGCVSQQRYERASWMKSSLEEGISMLKSIEFLSTKWKNLIPESSISSGKSLPLRALDVLKYEEVDMELLARAVPEPLKKYTQCRELAERLKIEATYESVLFHQQQEIKEVQRDEALQLPKDLDYLTLKDISLSYEVREKLHFSRPQTIGAASRIPGVTAAAIVNLLRFVKTTQQRQAAMNRIPKTDQQLHDTDRLEESQL", "length": 720, "header": "tr|F6RVI7-1|F6RVI7_BOVIN Isoform 1 of 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial OS=Bos taurus OX=9913 GN=MTO1 PE=3 SV=1 CANONICAL=F6RVI7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T966-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T966/entry", "sequence": { "sequence": "MFCIRGCGRRVAASLTKQHLASVRFGGDSAAPWTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKYRVSGVVLADGSKVYAESVVLTTGTFLRGMIVIGLEMHPAGRLGDQPAVGLAQTLEKLGFVVGRLKTGTPPRIAKESVNFSILNKQTPDNPSIPFSFINQTVWIKPEDQLPCYLTHTNPRVDEIVLENLHLNCHVKETTRGPRYCPSIESKVLRFPNRVHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLENAKMIQPGYGVQYDYMDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVRHKPPFVISRTEGYIGVLIDDLTTLGTNEPYRMFTSRAEFRLSLRPDNADSRLTFRGYKEAGCVSQQRYERASWMKSSLEEGISMLKSIEFLSTKWKNLIPESSISSGKSLPLRALDVLKYEEVDMELLARAVPEPLKKYTQCRELAERLKIEDWGCQ", "length": 590, "header": "tr|A0AAA9T966-1|F6RVI7_BOVIN Computationally mapped isoform of 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial OS=Bos taurus OX=9913 GN=MTO1 PE=3 SV=1 CANONICAL=F6RVI7-1" }, "locus": { "chromosome": "9", "start_pos": 12990046, "end_pos": 12969841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125014.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125014.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094539.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094539.1" } ] } }, { "isoform_ac": "F6RVI7-1", "url": "https://www.uniprot.org/uniprotkb/F6RVI7/entry", "sequence": { "sequence": "MFCIRGCGRRVAASLTKQHLASVRFGGDSAAPWTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKYRVSGVVLGSRFPSSGAFLGTGVVFLSVILSLTSCRADGSKVYAESVVLTTGTFLRGMIVIGLEMHPAGRLGDQPAVGLAQTLEKLGFVVGRLKTGTPPRIAKESVNFSILNKQTPDNPSIPFSFINQTVWIKPEDQLPCYLTHTNPRVDEIVLENLHLNCHVKETTRGPRYCPSIESKVLRFPNRVHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLENAKMIQPGYGVQYDYMDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVRHKPPFVISRTEGYIGVLIDDLTTLGTNEPYRMFTSRAEFRLSLRPDNADSRLTFRGYKEAGCVSQQRYERASWMKSSLEEGISMLKSIEFLSTKWKNLIPESSISSGKSLPLRALDVLKYEEVDMELLARAVPEPLKKYTQCRELAERLKIEATYESVLFHQQQEIKEVQRDEALQLPKDLDYLTLKDISLSYEVREKLHFSRPQTIGAASRIPGVTAAAIVNLLRFVKTTQQRQAAMNRIPKTDQQLHDTDRLEESQL", "length": 720, "header": "tr|F6RVI7-1|F6RVI7_BOVIN Isoform 1 of 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial OS=Bos taurus OX=9913 GN=MTO1 PE=3 SV=1 CANONICAL=F6RVI7-1" }, "locus": { "chromosome": "9", "start_pos": 12990191, "end_pos": 12969841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022398.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022398.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022398.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022398.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "pmid": "" }, { "name": "GTPBP3-MTO1 complex", "id": "GO:7770010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:7770010", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "pmid": "" }, { "name": "tRNA 5-taurinomethyluridine synthase activity", "id": "GO:0160236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160236", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "pmid": "" }, { "name": "mitochondrial tRNA wobble uridine modification", "id": "GO:0070899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070899", "evidence": [ { "database": "UniProtKB", "id": "F6RVI7", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83279", "name": "", "equation": "uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83279", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83279" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVI7" }, { "id": "SM01228", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain", "eco_id": "ECO_0000259", "start_pos": 614, "end_pos": 687, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 455, "end_pos": 457 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QVR0-1", "uniprot_ac": "F6QVR0", "uniprot_id": "F6QVR0_BOVIN", "mass": { "chemical_mass": 89740.0, "monoisotopic_mass": 89740.0 }, "refseq": { "ac": "XP_005219142", "name": "protein Aster-A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219142" }, "gene_names": [ { "name": "GRAMD1A", "type": "recommended", "evidence": [ { "id": "F6QVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ] }, { "name": "GRAMD1A", "type": "synonym", "evidence": [ { "id": "XP_005219142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219142" } ] } ], "protein_names": [ { "name": "GRAM domain containing 1A", "type": "synonym", "evidence": [ { "id": "F6QVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVR0/entry#names_and_taxonomy" } ] }, { "name": "protein Aster-A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005219142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219142" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GRAMD1A", "url": "https://www.uniprot.org/uniprotkb/F6QVR0", "locus": { "chromosome": "18", "start_pos": 45767893, "end_pos": 45742720, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003820", "url": "https://www.ensembl.org/id/ENSBTAG00000003820" } ] } } ], "crossref": [ { "id": "F6QVR0", "url": "https://alphafold.ebi.ac.uk/entry/F6QVR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003820", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003820", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507027", "url": "https://www.ncbi.nlm.nih.gov/gene/507027", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507027", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507027", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M539", "url": "https://www.orthodb.org/?gene=A0A3Q1M539", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QVR0", "url": "https://www.orthodb.org/?gene=F6QVR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23319", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23319", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23319:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23319:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005219142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219142", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M539", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M539", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M539-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M539-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCJ7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVR0-1", "url": "https://www.uniprot.org/uniprotkb/F6QVR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEFLPLLPCTPLLTQDVCAQDSRVPPAKEPSQEAQGGRVHGPAPKRWKLLEVPTIQITPASNGESPPCTPPAQRLQLPRTPDRESSPQDSTTPHSGRSTPSSSPSLRKRLQLLPTSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTENEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGSPKDVGDVIALSDITPSGAADHSQEPSPAGSRRGRITPNLSRASSDADHGAEEDKEEQTDSQPDASSSQTVTPVAEPPSAEPTPPDGPTSLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQDFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEGGKDTRGLLSGLRRRKRPLSWRAHGDGTPHPDPDPCARTGMHTSGSLSSRFSEPSMDQGPGAGTPSALVLISIVLIVLIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDSQPQPDDSFS", "length": 808, "header": "tr|F6QVR0-1|F6QVR0_BOVIN Isoform 1 of GRAM domain containing 1A OS=Bos taurus OX=9913 GN=GRAMD1A PE=4 SV=2 CANONICAL=F6QVR0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M539-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M539/entry", "sequence": { "sequence": "MFDTTPHSGRSTPSSSPSLRKRLQLLPTSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTENEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGSPKDVGDVIALSDITPSGAADHSQEPSPAGSRRGRITPNLSRASSDADHGAEEDKEEQTDSQPDASSSQTVTPVAEPPSAEPTPPDGPTSLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQDFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEGGKDTRGLLSGLRRRKRPLSWRAHGDGTPHPDPDPCARTGMHTSGSLSSRFSEPSMDQGPGAGTPSALVLISIVLIVLIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDSQPQPDDSFS", "length": 720, "header": "tr|A0A3Q1M539-1|A0A3Q1M539_BOVIN Computationally mapped isoform of GRAM domain containing 1A OS=Bos taurus OX=9913 GN=GRAMD1A PE=4 SV=3 CANONICAL=F6QVR0-1" }, "locus": { "chromosome": "18", "start_pos": 45767536, "end_pos": 45748234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071456.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071456.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068760.3", "url": "https://www.ensembl.org/id/ENSBTAP00000068760.3" } ] } }, { "isoform_ac": "A0AAA9TCJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCJ7/entry", "sequence": { "sequence": "MNSPRTGSWGACSGSFCEEVEQEPSSSPPSTTPHSGRSTPSSSPSLRKRLQLLPTSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTENEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGSPKDVGDVIALSDITPSGAADHSQEPSPAGSRRGRITPNLSRASSDADHGAEEDKEEQTDSQPDASSSQTVTPVAEPPSAEPTPPDGPTSLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQDFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEGGKDTRGLLSGLRRRKRPLSWRAHGDGTPHPDPDPCARTGMHTSGSLSSRFSEPSMDQGPGAGTPSALVLISIVICVSLIVLIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDSQPQPDDSFS", "length": 751, "header": "tr|A0AAA9TCJ7-1|F6QVR0_BOVIN Computationally mapped isoform of GRAM domain containing 1A OS=Bos taurus OX=9913 GN=GRAMD1A PE=4 SV=1 CANONICAL=F6QVR0-1" }, "locus": { "chromosome": "18", "start_pos": 45767536, "end_pos": 45752555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099345.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099345.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094583.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094583.1" } ] } }, { "isoform_ac": "A0AAA9TVV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV8/entry", "sequence": { "sequence": "MFDTTPHSGRSTPSSSPSLRKRLQLLPTSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTENEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGSPKDVGDVIALSDITPSGAADHSQEPSPAGSRRGRITPNLSRASSDADHGAEEDKEEQTDSQPDASSSQTVTPVAEPPSAEPTPPDGPTSLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQDFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEGGKDTRGLLSGLRRRKRPLSWRAHGDGTPHPDPDPCARTGMHTSGSLSSRFSEPSMDQGPGAGTPSALVLISIVLIVLIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDSQPQPDDSFS", "length": 713, "header": "tr|A0AAA9TVV8-1|F6QVR0_BOVIN Computationally mapped isoform of GRAM domain containing 1A OS=Bos taurus OX=9913 GN=GRAMD1A PE=4 SV=1 CANONICAL=F6QVR0-1" }, "locus": { "chromosome": "18", "start_pos": 45767536, "end_pos": 45748234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099607.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099607.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102476.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102476.1" } ] } }, { "isoform_ac": "F6QVR0-1", "url": "https://www.uniprot.org/uniprotkb/F6QVR0/entry", "sequence": { "sequence": "MAEFLPLLPCTPLLTQDVCAQDSRVPPAKEPSQEAQGGRVHGPAPKRWKLLEVPTIQITPASNGESPPCTPPAQRLQLPRTPDRESSPQDSTTPHSGRSTPSSSPSLRKRLQLLPTSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTENEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGSPKDVGDVIALSDITPSGAADHSQEPSPAGSRRGRITPNLSRASSDADHGAEEDKEEQTDSQPDASSSQTVTPVAEPPSAEPTPPDGPTSLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQDFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEGGKDTRGLLSGLRRRKRPLSWRAHGDGTPHPDPDPCARTGMHTSGSLSSRFSEPSMDQGPGAGTPSALVLISIVLIVLIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDSQPQPDDSFS", "length": 808, "header": "tr|F6QVR0-1|F6QVR0_BOVIN Isoform 1 of GRAM domain containing 1A OS=Bos taurus OX=9913 GN=GRAMD1A PE=4 SV=2 CANONICAL=F6QVR0-1" }, "locus": { "chromosome": "18", "start_pos": 45767536, "end_pos": 45743703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004977.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004977.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004977.5", "url": "https://www.ensembl.org/id/ENSBTAP00000004977.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 411, "start_aa": "Thr", "end_pos": 411, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr411", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 692, "start_aa": "Thr", "end_pos": 692, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr692", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:507027", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507027", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "organelle membrane contact site", "id": "GO:0044232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044232", "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane contact site", "id": "GO:0140268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140268", "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular sterol transport", "id": "GO:0032366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032366", "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "pmid": "" }, { "name": "cholesterol transfer activity", "id": "GO:0120020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120020", "evidence": [ { "database": "UniProtKB", "id": "F6QVR0", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QVR0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 808, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QVR0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QVR0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVR0" }, { "id": "PS51778", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51778" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VASt", "eco_id": "ECO_0000259", "start_pos": 455, "end_pos": 626, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 145, 411, 692 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 367, "end_pos": 369 }, { "start_pos": 436, "end_pos": 438 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RMH4-1", "uniprot_ac": "F6RMH4", "uniprot_id": "F6RMH4_BOVIN", "mass": { "chemical_mass": 76054.0, "monoisotopic_mass": 76054.0 }, "refseq": {}, "gene_names": [ { "name": "TRAF3IP3", "type": "recommended", "evidence": [ { "id": "F6RMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ] } ], "protein_names": [ { "name": "TRAF3 interacting protein 3", "type": "synonym", "evidence": [ { "id": "F6RMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMH4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRAF3IP3", "url": "https://www.uniprot.org/uniprotkb/F6RMH4", "locus": { "chromosome": "16", "start_pos": 73524538, "end_pos": 73550650, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002846", "url": "https://www.ensembl.org/id/ENSBTAG00000002846" } ] } } ], "crossref": [ { "id": "F6RMH4", "url": "https://alphafold.ebi.ac.uk/entry/F6RMH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002846", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002846", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR051176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KEKEWDF", "url": "https://omabrowser.org/oma/group/KEKEWDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RMH4", "url": "https://www.orthodb.org/?gene=F6RMH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TGY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWW5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RMH4-1", "url": "https://www.uniprot.org/uniprotkb/F6RMH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGKSVHRTDLQDLEFQTPHTHTPATFCRMWTAKPTSKAAVQKERQYQEGKRSGGPEPWIEILPLCGDHSQDLPRSWDAFLICWGWRLGPQTRAAIPGTGSQATTGAQEVIMIGPDPRPAPGLARWAESYEAKSERRQETRESRRCRPNVTTCRLVGKAPRTQQREQLRRARQQQFFRRRNLEVEEKGEAQSPPAREPGPSRRTGQATDLKEPLSWANRISSPRQQVSGTSCEVFATQHHPPSGAWRDPAGHCPTQAGGLPPQASPTKKAPKHHRGTQTKAGETQSTIKNDASQQTNYGVAVLDKEIIQLSEYLKEALQRELILKQKMVILQDLLSTLIQASDSTWKGQLNEDKLKGKLRSLENQLYACTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMSAEQQLQSTQRSLALAEQKCEEWKSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDSQMNQALRLLESEHQELQARIECLQEDRDLCSSDTQHLQDQLKRSEEEKLALVTKVQQLQSLLQNQSLQLQKQEKLLTKKDQALPVRSPEPSHNEVEPEGPGKEQDLDFRDELQKKTLQLLAKEKECRELLSELDNLSDEYLSCLRKLQHCREELSQSQQPPPRRQCGRWLLMLMALAAIAVAVMLANKDSLMLW", "length": 666, "header": "tr|F6RMH4-1|F6RMH4_BOVIN Isoform 1 of TRAF3 interacting protein 3 OS=Bos taurus OX=9913 GN=TRAF3IP3 PE=4 SV=2 CANONICAL=F6RMH4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TGY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGY8/entry", "sequence": { "sequence": "MIGPDPRPAPGLARWAESYEAKSERRQETRESRRCRPNVTTCRLVGKAPRTQQREQLRRARQQQFFRRRNLEVEEKGEAQSPPAREPGPSRRTGQATDLKEPLSWANRISSPRQQVSGTSCEVFATQHHPPSGAWRDPAGHCPTQAGGLPPQASPTKKAPKHHRGTQTKAGETQSTIKNDASQQTNYGVAVLDKEIIQLSEYLKEALQRELILKQKMVILQDLLSTLIQASDSTWKGQLNEDKLKGKLRSLENQLYACTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMSAEQQLQSTQRSLALAEQKCEEWKSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDSQMNQALRLLESEHQELQARIECLQEDRDLCSSDTQHLQEAVWPMAPDADGAGCYSGGSDAGQ", "length": 422, "header": "tr|A0AAA9TGY8-1|F6RMH4_BOVIN Computationally mapped isoform of TRAF3 interacting protein 3 OS=Bos taurus OX=9913 GN=TRAF3IP3 PE=4 SV=1 CANONICAL=F6RMH4-1" }, "locus": { "chromosome": "16", "start_pos": 73543856, "end_pos": 73524722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133217.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133217.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096133.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096133.1" } ] } }, { "isoform_ac": "A0AAA9TWW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW5/entry", "sequence": { "sequence": "MIGPDPRPAPGLARWAESYEAKSERRQETRESRRCRPNVTTCRLVGKAPRTQQREQLRRARQQQFFRRRNLEVEEKGEAQSPPAREPGPSRRTGQVSGTSCEVFATQHHPPSGAWRDPAGHCPTQAGGLPPQASPTKKAPKHHRGTQTKAGETQSTIKNDASQQTNYGVAVLDKEIIQLSEYLKEALQRELILKQKMVILQDLLSTLIQASDSTWKGQLNEDKLKGKLRSLENQLYACTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMSAEQQLQSTQRSLALAEQKCEEWKSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDSQMNQALRLLESEHQELQARIECLQEDRDLCSSDTQHLQDQLKRSEEEKLALVTKVQQLQKAEGWTT", "length": 406, "header": "tr|A0AAA9TWW5-1|F6RMH4_BOVIN Computationally mapped isoform of TRAF3 interacting protein 3 OS=Bos taurus OX=9913 GN=TRAF3IP3 PE=4 SV=1 CANONICAL=F6RMH4-1" }, "locus": { "chromosome": "16", "start_pos": 73543856, "end_pos": 73527417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105704.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105704.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102851.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102851.1" } ] } }, { "isoform_ac": "F6RMH4-1", "url": "https://www.uniprot.org/uniprotkb/F6RMH4/entry", "sequence": { "sequence": "MRAGKSVHRTDLQDLEFQTPHTHTPATFCRMWTAKPTSKAAVQKERQYQEGKRSGGPEPWIEILPLCGDHSQDLPRSWDAFLICWGWRLGPQTRAAIPGTGSQATTGAQEVIMIGPDPRPAPGLARWAESYEAKSERRQETRESRRCRPNVTTCRLVGKAPRTQQREQLRRARQQQFFRRRNLEVEEKGEAQSPPAREPGPSRRTGQATDLKEPLSWANRISSPRQQVSGTSCEVFATQHHPPSGAWRDPAGHCPTQAGGLPPQASPTKKAPKHHRGTQTKAGETQSTIKNDASQQTNYGVAVLDKEIIQLSEYLKEALQRELILKQKMVILQDLLSTLIQASDSTWKGQLNEDKLKGKLRSLENQLYACTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMSAEQQLQSTQRSLALAEQKCEEWKSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDSQMNQALRLLESEHQELQARIECLQEDRDLCSSDTQHLQDQLKRSEEEKLALVTKVQQLQSLLQNQSLQLQKQEKLLTKKDQALPVRSPEPSHNEVEPEGPGKEQDLDFRDELQKKTLQLLAKEKECRELLSELDNLSDEYLSCLRKLQHCREELSQSQQPPPRRQCGRWLLMLMALAAIAVAVMLANKDSLMLW", "length": 666, "header": "tr|F6RMH4-1|F6RMH4_BOVIN Isoform 1 of TRAF3 interacting protein 3 OS=Bos taurus OX=9913 GN=TRAF3IP3 PE=4 SV=2 CANONICAL=F6RMH4-1" }, "locus": { "chromosome": "16", "start_pos": 73550451, "end_pos": 73524700, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003691.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003691.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003691.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003691.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A6X1-1", "protein_name": "TRAF3 interacting protein 3", "gene_name": "TRAF3IP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSPDPRPAPGLARWAESYEAKCERRQETRESRRRRPNVTTCRQVGKALRTQQREQFQKARQQQFFRLRHLEVEEKGQAERSQTRQPGSSRAGQAPDLKEPWPWANRISSPGQQVSGTSAEVFPAQRHPPSGARRDSAVQKLPKQHRGTQTKAEETQPTTKNDASQQTNYGVAVLDKEIIQLSEYLKEALHRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQNYSPRGMKKVILEMEDQKHSYEQKAKESLQKVLEEKMSAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRLLENEHQELQAKIARLQGDRDLCSSDTQHLQDQLQKSEEEKLALVTKVQQLQSLLQSQSLQLQEQEKRLTKKDQALEWSPKPSQNEVEPEGPGKEKDWDFRDQLQEKTLQLLAKEKECRDLHSELDNLSDEYLSCLRKLQRCREELSLGQRPPPTRQCGRWLPALMVLTAMALAVFLAHKDSLMI", "length": 535 }, "evidence": [ { "id": "F6RMH4", "url": "https://omabrowser.org/oma/group/F6RMH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AFD1-1", "protein_name": "TRAF3 interacting protein 3", "gene_name": "TRAF3IP3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MISPPERARPRRAGESYEEKCERRQETREALRRRGHHAHSARRPGRPEEQPQSPRQREFLRRRNLGGTAGELSAPILLQRPWSHPMCPSTIPPLGLSSPTGILAEAIPVPHTSKSTRGTQTPASTRVKDSGQQTDCGNTVFSKEIVQLSGYLKEALHRELLLKQKMVILQELLATLLHASEKSWQGQLNEDKLKCKLRALENQLQACTQSYSKECMKKILIEMEDQKQTYEQKAKEALQKMLEDKLQAEQQLQNSQRCLAVTREDLALWKEHYTMLKSEWAQMAKAHSELKSNLHTVQSQLQHMATQNEELCQALDILQHEHAELQQHADNLQQDNQLQAKHISNIEGKLQKEQNQKLILEATISHLQNLMQNQNNEQKTQEVTVQRKDQGFTTQTPPLTPAKEVQNALSEHPKEKAEESLRDEMQERTSQLTAKEKEVCMGTRAAEGQTPPRHTAHTQVKHHKCCGSPTSAGVPEATGLPPTDPCLRSPPECQELRAELEALSEEYRCCLSCLHQCRQELNQSQTVKRKRGNWLPLLLAVIVMAVAAVLASYRP", "length": 555 }, "evidence": [ { "id": "F6RMH4", "url": "https://omabrowser.org/oma/group/F6RMH4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8C0G2-1", "protein_name": "TRAF3-interacting JNK-activating modulator", "gene_name": "Traf3ip3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISSDSRSSPGLARWAESYEAKCERRQETRENRRRRRNETTCRQPGKVLRTQHKERLQGARQLQFLKRRNLEEEKKGQAREQGPSSKTDGGTGQVSILKESLPGANKASFPGQQETGISSEVFPALHHSSSGIQRDLGGHHASHGRAFPPQDSDIKKPHRQHRGTQTKAEEALPTIKNDASQQTNCGVAVLDKDIIQLSEYLKEALHRELILKKKMVILQDLLPALIRASDSSWKGQLNEDKLKGKLRSLENQLYTCLQKHSPWGMKKVLLEMEDQRSSYEQKAKASLQKVLEEKMCAEQQLQRAQLSLALAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALQLLENEHQELQTKLESLQGDGEQQSSETQDLQDQLKKSEEEKQALVSKVQQLQSLLQNQSLQLQEQEKLLKKDQGLPVWNPKLSLDEVKPEGTRKEKEEELRDQLQKETFQLQVKENELQCGQWLPVLMVVIATALAVFLANKGNLVI", "length": 513 }, "evidence": [ { "id": "F6RMH4", "url": "https://omabrowser.org/oma/group/F6RMH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y228-1", "protein_name": "TRAF3-interacting JNK-activating modulator", "gene_name": "TRAF3IP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISPDPRPSPGLARWAESYEAKCERRQEIRESRRCRPNVTTCRQVGKTLRIQQREQLQRARLQQFFRRRNLELEEKGKAQHPQAREQGPSRRPGQVTVLKEPLSCARRISSPREQVTGTSSEVFPAQHPPPSGICRDLSDHLSSQAGGLPPQDTPIKKPPKHHRGTQTKAEGPTIKNDASQQTNYGVAVLDKEIIQLSDYLKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYTCTQKYSPWGMKKVLLEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDWRTLGTQHRELESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQGDRDLCSLDTQDLQDQLKRSEAEKLTLVTRVQQLQGLLQNQSLQLQEQEKLLTKKDQALPVWSPKSFPNEVEPEGTGKEKDWDLRDQLQKKTLQLQAKEKECRELHSELDNLSDEYLSCLRKLQHCREELNQSQQLPPRRQCGRWLPVLMVVIAAALAVFLANKDNLMI", "length": 551 }, "evidence": [ { "id": "F6RMH4", "url": "https://omabrowser.org/oma/group/F6RMH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" }, { "name": "zf-TRAF domain binding", "id": "GO:0044198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044198", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "F6RMH4", "url": "https://www.uniprot.org/uniprotkb/F6RMH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RMH4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 666, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RMH4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RMH4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 607, "end_pos": 609 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N010-1", "uniprot_ac": "G3N010", "uniprot_id": "G3N010_BOVIN", "mass": { "chemical_mass": 15583.0, "monoisotopic_mass": 15583.0 }, "refseq": { "ac": "XP_002695437", "name": "cdc42 effector protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695437" }, "gene_names": [ { "name": "CDC42EP5", "type": "recommended", "evidence": [ { "id": "G3N010", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N010" } ] }, { "name": "CDC42EP5", "type": "synonym", "evidence": [ { "id": "XP_002695437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695437" } ] } ], "protein_names": [ { "name": "CDC42 effector protein 5", "type": "synonym", "evidence": [ { "id": "G3N010", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N010/entry#names_and_taxonomy" } ] }, { "name": "cdc42 effector protein 5", "type": "synonym", "evidence": [ { "id": "XP_002695437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695437" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N010", "url": "https://www.uniprot.org/uniprotkb/G3N010" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDC42EP5", "url": "https://www.uniprot.org/uniprotkb/G3N010", "locus": { "chromosome": "18", "start_pos": 62881749, "end_pos": 62912110, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045989", "url": "https://www.ensembl.org/id/ENSBTAG00000045989" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045989", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045989", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618745", "url": "https://www.ncbi.nlm.nih.gov/gene/618745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618745", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618745", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"https://www.uniprot.org/uniprotkb/A0AAA9TJC6/entry", "sequence": { "sequence": "MWARAFIVVATRNNGQKKMPVLKQLGPAQPKKRPERGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRTAPPPAVPQASPPALRAPAPADPLLSFHLDLGPSMLDAVLGVMDAERPGAAAAKPDVDPGPGAQHPRARCLANADLEPDDVIGL", "length": 171, "header": "tr|A0AAA9TJC6-1|G3N010_BOVIN Computationally mapped isoform of CDC42 effector protein 5 OS=Bos taurus OX=9913 GN=CDC42EP5 PE=3 SV=1 CANONICAL=G3N010-1" }, "locus": { "chromosome": "18", "start_pos": 62911965, "end_pos": 62891330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131430.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131430.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097271.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097271.1" } ] } }, { "isoform_ac": "G3N010-1", "url": "https://www.uniprot.org/uniprotkb/G3N010/entry", "sequence": { "sequence": "MPVLKQLGPAQPKKRPERGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRTAPPPAVPQASPPALRAPAPADPLLSFHLDLGPSMLDAVLGVMDAERPGAAAAKPDVDPGPGAQHPRARCLANADLEPDDVIGL", "length": 153, "header": "tr|G3N010-1|G3N010_BOVIN Isoform 1 of CDC42 effector protein 5 OS=Bos taurus OX=9913 GN=CDC42EP5 PE=3 SV=2 CANONICAL=G3N010-1" }, "locus": { "chromosome": "18", "start_pos": 62891788, "end_pos": 62891330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094040.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094040.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090654.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090654.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618745", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618745", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6NZY7-1", "protein_name": "Cdc42 effector 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}, { "name": "NHERF2", "type": "synonym", "evidence": [ { "id": "XP_005224625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224625" } ] }, { "name": "SLC9A3R2", "type": "synonym", "evidence": [ { "id": "XP_005224625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224625" } ] } ], "protein_names": [ { "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF", "type": "recommended", "evidence": [ { "id": "G3N1L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L5/entry#names_and_taxonomy" } ] }, { "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005224625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224625" } ] } ], "function": [ { "annotation": "Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to 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"Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005224625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224625", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TL47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL47-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MD15", "url": "https://www.uniprot.org/uniprotkb/F1MD15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MD15-1", "url": "https://www.uniprot.org/uniprotkb/F1MD15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1L5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1L5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPEPLRPRLCRLVRGEHGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDKETDEELHRRQLTCTEEMARRGLPPAHDPWEPKPDWARAGSLSSEAAQEDTNGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEAQLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSSAQLNGGSVCSSRSDLPGLDKDTEDGSTWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "length": 337, "header": "tr|G3N1L5-1|G3N1L5_BOVIN Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF OS=Bos taurus OX=9913 GN=NHERF2 PE=4 SV=2 CANONICAL=G3N1L5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TL47-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL47/entry", "sequence": { "sequence": "MAAPEPLRPRLCRLVRGEHGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDKETDEELHRRQLTCTEEMARRGLPPAHDPWEPKPDWARAGSLSSEAAQEDTNGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEAQLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSSAQDGSTWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "length": 316, "header": "tr|A0AAA9TL47-1|G3N1L5_BOVIN Computationally mapped isoform of Na(+)/H(+) exchange regulatory cofactor NHE-RF OS=Bos taurus OX=9913 GN=NHERF2 PE=4 SV=1 CANONICAL=G3N1L5-1" }, "locus": { "chromosome": "25", "start_pos": 1588045, "end_pos": 1576746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104891.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104891.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099166.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099166.1" } ] } }, { "isoform_ac": "A0AAA9TW84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW84/entry", "sequence": { "sequence": "MAAPEPLRPRLCRLVRGEHGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDKETDEELHRRQLTCTEEMARRGLPPAHDPWEPKPDWARAGSLSSEAAQEDTNGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEPRPHPLRTCSLNTCNKTNLSLHTISSHPLSSSHPKWESQGQGWGLAGFRAGAVGAALCPFLGWAV", "length": 287, "header": "tr|A0AAA9TW84-1|G3N1L5_BOVIN Computationally mapped isoform of Na(+)/H(+) exchange regulatory cofactor NHE-RF OS=Bos taurus OX=9913 GN=NHERF2 PE=4 SV=2 CANONICAL=G3N1L5-1" }, "locus": { "chromosome": "25", "start_pos": 1588626, "end_pos": 1576746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091424.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091424.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102590.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102590.2" } ] } }, { "isoform_ac": "F1MD15-1", "url": "https://www.uniprot.org/uniprotkb/F1MD15/entry", "sequence": { "sequence": "MARSGNAVPSAPAPGAPPQSPSRGLVQDTNGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEAQLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSSAQLNGGSVCSSRSDLPGLDKDTEDGSTWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "length": 226, "header": "tr|F1MD15-1|G3N1L5_BOVIN Computationally mapped isoform of Na(+)/H(+) exchange regulatory cofactor NHE-RF OS=Bos taurus OX=9913 GN=NHERF2 PE=4 SV=3 CANONICAL=G3N1L5-1" }, "locus": { "chromosome": "25", "start_pos": 1588045, "end_pos": 1581888, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049790.4", "url": "https://www.ensembl.org/id/ENSBTAT00000049790.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046626.3", "url": "https://www.ensembl.org/id/ENSBTAP00000046626.3" } ] } }, { "isoform_ac": "G3N1L5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1L5/entry", "sequence": { "sequence": "MAAPEPLRPRLCRLVRGEHGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDKETDEELHRRQLTCTEEMARRGLPPAHDPWEPKPDWARAGSLSSEAAQEDTNGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEAQLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSSAQLNGGSVCSSRSDLPGLDKDTEDGSTWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "length": 337, "header": "tr|G3N1L5-1|G3N1L5_BOVIN Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF OS=Bos taurus OX=9913 GN=NHERF2 PE=4 SV=2 CANONICAL=G3N1L5-1" }, "locus": { "chromosome": "25", "start_pos": 1588045, "end_pos": 1576746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065244.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065244.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055763.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055763.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YXB1-1", "protein_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF", "gene_name": "SLC9A3R2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAKDQLKPRLCHMLKGENGYGFHLHGEKGKSGQFIRKVEPGSPAEAAGLRAGDRVVEVNGLNVEQETHHQVVQRIKAVETETRLLVVDKETDEYLCSLRLTCTEEMAHSGILLGSSISPSKSVGSDNGEVWKPQLELNAGSLQRHSHSFSSHSSRKDLNGQKDLCPRLCHLKKGPSGYGFNLHSEKSRPGQFIRSVDPDSPASRAGLRPQDRLVEVNGINVEGLRHSEVVSHIKARETEARLLVVDPETDEYFKKLGVTPTEEHTKGVVPQPMTNGSAQMQLNGGSTSSSHSDLQSPGKESEDGDSEKRDPFEESGLSLSPTAAEAKEKVRAKRVKKRAPQMDWNKKREIFSNF", "length": 354 }, "evidence": [ { "id": "G3N1L5", "url": "https://omabrowser.org/oma/group/G3N1L5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q15599-1", "protein_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "gene_name": "NHERF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF", "length": 337 }, "evidence": [ { "id": "G3N1L5", "url": "https://omabrowser.org/oma/group/G3N1L5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920G2-1", "protein_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "gene_name": "Nherf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPESLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVHRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGHKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASLSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVVPTEDHVEGPLPSPVTNGTSLAQLNGGSVCSSRSDLPGSEKDNEDGSAWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "length": 337 }, "evidence": [ { "id": "G3N1L5", "url": "https://omabrowser.org/oma/group/G3N1L5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JHL1-1", "protein_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF2", "gene_name": "Nherf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPESLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGQKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASHSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVVPTEEHVEGPLPSPVTNGTSPAQLNGGSVCSSRSDLPGSEKDNEDGSTWKRDPFQESGLHLSPTAAEAKEKARATRVNKRAPQMDWNRKREIFSNF", "length": 337 }, "evidence": [ { "id": "G3N1L5", "url": "https://omabrowser.org/oma/group/G3N1L5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "G3N1L5", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1L5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 337, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1L5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1L5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L5" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 91, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1U1-1", "uniprot_ac": "G3N1U1", "uniprot_id": "G3N1U1_BOVIN", "mass": { "chemical_mass": 27596.0, "monoisotopic_mass": 27596.0 }, "refseq": {}, "gene_names": [ { "name": "CENPV", "type": "recommended", "evidence": [ { "id": "G3N1U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ] } ], "protein_names": [ { "name": "Centromere protein V", "type": "synonym", "evidence": [ { "id": "G3N1U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1U1/entry#names_and_taxonomy" } ] } ], 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"https://www.ncbi.nlm.nih.gov/gene/521064", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N1U1", "url": "https://www.orthodb.org/?gene=G3N1U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28620:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28620:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TPJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1U1-1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRARSGGATKPRGQKRPGTSRAPASAPSADRARRPAVQAGGGSRAAARQPAAKRRSPPVQEAGPGEPPPVPPLPPPPPSALTASELDLGEQRERWETFQKRQRLSFEGAAKLLLDTYEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNKHFIVPASRFKLLKGADSITTYTFNTHKAQHTFCKRCGVQSFYSPRSNPGGFVVLFLYSEDKVQVPEGLRLSVSGCGPALGTEPHGRPWTFLAP", "length": 254, "header": "tr|G3N1U1-1|G3N1U1_BOVIN Isoform 1 of Centromere protein V OS=Bos taurus OX=9913 GN=CENPV PE=3 SV=3 CANONICAL=G3N1U1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TPJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPJ1/entry", "sequence": { "sequence": "MRRARSGGATKPRGQKRPGTSRAPASAPSADRARRPAVQAGGGSRAAARQPAAKRRSPPVQEAGPGEPPPVPPLPPPPPSALTASELDLGEQRERWETFQKRQRLSFEGAAKLLLDTYEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNKHFIVPASRFKLLKGADSITTYTFNTHKAQHTFCKRCGVQSFYSPRSNPGGFELLSAPFLLHGASFPPAFLYGWGHI", "length": 237, "header": "tr|A0AAA9TPJ1-1|G3N1U1_BOVIN Computationally mapped isoform of Centromere protein V OS=Bos taurus OX=9913 GN=CENPV PE=3 SV=1 CANONICAL=G3N1U1-1" }, "locus": { "chromosome": "19", "start_pos": 33282306, "end_pos": 33274633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123434.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123434.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100319.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100319.1" } ] } }, { "isoform_ac": "G3N1U1-1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1/entry", "sequence": { "sequence": "MRRARSGGATKPRGQKRPGTSRAPASAPSADRARRPAVQAGGGSRAAARQPAAKRRSPPVQEAGPGEPPPVPPLPPPPPSALTASELDLGEQRERWETFQKRQRLSFEGAAKLLLDTYEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNKHFIVPASRFKLLKGADSITTYTFNTHKAQHTFCKRCGVQSFYSPRSNPGGFVVLFLYSEDKVQVPEGLRLSVSGCGPALGTEPHGRPWTFLAP", "length": 254, "header": "tr|G3N1U1-1|G3N1U1_BOVIN Isoform 1 of Centromere protein V OS=Bos taurus OX=9913 GN=CENPV PE=3 SV=3 CANONICAL=G3N1U1-1" }, "locus": { "chromosome": "19", "start_pos": 33293489, "end_pos": 33274633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065404.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065404.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055844.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055844.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "carbon-sulfur lyase activity", "id": "GO:0016846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016846", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of chromosome organization", "id": "GO:0033044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "pericentric heterochromatin formation", "id": "GO:0031508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031508", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "G3N1U1", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1U1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 254, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1U1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1U1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1U1" }, { "id": "PS51891", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51891" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CENP-V/GFA", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 250, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXI9-1", "uniprot_ac": "G3MXI9", "uniprot_id": "G3MXI9_BOVIN", "mass": { "chemical_mass": 38337.0, "monoisotopic_mass": 38337.0 }, "refseq": { "ac": "XP_002696375", "name": "cyclin-O", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696375" }, "gene_names": [ { "name": "CCNO", "type": "recommended", "evidence": [ { "id": "G3MXI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ] }, { "name": "CCNO", "type": "synonym", "evidence": [ { "id": "XP_002696375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696375" } ] } ], "protein_names": [ { "name": "Cyclin-O", "type": "recommended", "evidence": [ { "id": "G3MXI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXI9/entry#names_and_taxonomy" } ] }, { "name": "cyclin-O", "type": "synonym", "evidence": [ { "id": "XP_002696375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696375" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCNO", "url": "https://www.uniprot.org/uniprotkb/G3MXI9", "locus": { "chromosome": "20", "start_pos": 23904856, "end_pos": 23901218, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047594", "url": "https://www.ensembl.org/id/ENSBTAG00000047594" } ] } } ], "crossref": [ { "id": "G3MXI9", "url": "https://alphafold.ebi.ac.uk/entry/G3MXI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047594", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20722", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20722", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100301247", "url": "https://www.ncbi.nlm.nih.gov/gene/100301247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100301247", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSPRISH", "url": "https://omabrowser.org/oma/group/CSPRISH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXI9", "url": "https://www.orthodb.org/?gene=G3MXI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696375", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696375", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TYG7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXI9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTPGPTSPTSPMSPAAWAARQDARNLRAPVKKSRRPRLRRKQPLQPLNISPLPGDSGVCDLFESPSSGSDGTDSPAARDCSPVPGAAQQLAQLDLQTFRDYGQSCYAFRKAREGRFHPRESLARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLSTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFSLGAPTISFFLEHFTHARVEAGQAEVSEALEAQALARGVAELSLADYAFTSYTPSLLAICCLALADRMLQLPRPMDLRLGGHPEAALQDCLGKLQLLVAINGTSLTHMLPLQIREKCCLSSSLK", "length": 351, "header": "tr|G3MXI9-1|G3MXI9_BOVIN Isoform 1 of Cyclin-O OS=Bos taurus OX=9913 GN=CCNO PE=3 SV=1 CANONICAL=G3MXI9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TYG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYG7/entry", "sequence": { "sequence": "MCQLRARERVFSRESAGSVGLSAQPVRGQGCGRGNAQAEYLRAGGESGLVSALPGARVHFLRSPGVIERPSDFIMVTPGPTSPTSPMSPAAWAARQDARNLRAPVKKSRRPRLRRKQPLQPLNISPLPGDSGVCDLFESPSSGSDGTDSPAARDCSPVPGAAQQLAQLDLQTFRDYGQSCYAFRKAREGRFHPRESLARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLSTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFSLGAPTISFFLEHFTHARVEAGQAEVSEALEAQALARGVAELSLADYAFTSYTPSLLAICCLALADRMLQLPRPMDLRLGGHPEAALQDCLGKLQLLVAINGTSLTHMLPLQIREKCCLSSSLK", "length": 425, "header": "tr|A0AAA9TYG7-1|G3MXI9_BOVIN Computationally mapped isoform of Cyclin-O OS=Bos taurus OX=9913 GN=CCNO PE=3 SV=1 CANONICAL=G3MXI9-1" }, "locus": { "chromosome": "20", "start_pos": 23903852, "end_pos": 23901475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091454.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091454.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101729.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101729.1" } ] } }, { "isoform_ac": "G3MXI9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXI9/entry", "sequence": { "sequence": "MVTPGPTSPTSPMSPAAWAARQDARNLRAPVKKSRRPRLRRKQPLQPLNISPLPGDSGVCDLFESPSSGSDGTDSPAARDCSPVPGAAQQLAQLDLQTFRDYGQSCYAFRKAREGRFHPRESLARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLSTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFSLGAPTISFFLEHFTHARVEAGQAEVSEALEAQALARGVAELSLADYAFTSYTPSLLAICCLALADRMLQLPRPMDLRLGGHPEAALQDCLGKLQLLVAINGTSLTHMLPLQIREKCCLSSSLK", "length": 351, "header": "tr|G3MXI9-1|G3MXI9_BOVIN Isoform 1 of Cyclin-O OS=Bos taurus OX=9913 GN=CCNO PE=3 SV=1 CANONICAL=G3MXI9-1" }, "locus": { "chromosome": "20", "start_pos": 23903852, "end_pos": 23901697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066316.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066316.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054256.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054256.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100301247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301247", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHT5-1", "protein_name": "Cyclin-O", "gene_name": "Ccno", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LDVPGPASPASGAGRQDNHQNLRAPVKKSRRPRLRRKEPLRPLNACSLPGDSGVCDLFESPSSSSDGADSPAVSAVRDCSSLLSSAQPLTALDLQTFREYGQSCYDFRKAQENLFHPRESLARQPQVTAESRCKLLSWLLQVHRQFGLSFESLCLTVNTLDRFLLTTPVAADCFQLLGVTCLLIACKQVEVHPPRMKQLLALCGGAFSRQQLCNLECIVLHKLHFSLGAPTINFFLEHFTHSRVEAGQVEVTEALAAQTLARGVAELSLTDYAFTTYTPSLLAICCLALADRMLRHQRLMDLRLGEHPEATLLDCLGKLQKLVSINSSSLTHMLPAHIWEKCSLPQSWK", "length": 349 }, "evidence": [ { "id": "G3MXI9", "url": "https://omabrowser.org/oma/group/G3MXI9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SLN1-1", "protein_name": "Cyclin-O", "gene_name": "CCNO", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTPCPTSPASPATRAGRRDNQNLRAPVKKSRRPRLRRKQPLQALNPCLLPGDSGVCDLFESPSSGSDAADSPAPSTAPRCNSLPGPAQQLVQLDLQTFRDYGQTCYAFLKARENHFHPRESLARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLITTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFSLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYSFTSYTPSLLAICCLALADRMLQLPHPLDLGLGGHPEAALQDCLDKLQLLVAINGTSLTHMLPRQICEKCRLALSLK", "length": 351 }, "evidence": [ { "id": "G3MXI9", "url": "https://omabrowser.org/oma/group/G3MXI9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C242-1", "protein_name": "Cyclin-O", "gene_name": "Ccno", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVTPCPASPGSPAAGAGRRDSHQNLRAPVKKSRRPCLRRKKPLRPLNACSLPGDSGVCDLFESPSSSSDGADSPAVSAARDCSSLLNPAQPLTALDLQTFREYGQSCYDFRKAQENLFHPRESLARQPQVTAESRCKLLSWLLQVHRQFGLSFESLCLTVNTLDRFLLTTPVAADCFQLLGVTCLLIACKQVEVHPPRLKQLLALCGGAFSRQQLCNLECIVLHKLHFSLGAPTINFFLEHFTQWRMEAGQAEVTEALEAQTLARGVAELSLTDYAFTTYTPSLMAICCLALADGLLQHQHEMDLRLGEHPEATLQDCLGKLQTLVSINSSSLPRILPPQIWERCSLPQSWQ", "length": 352 }, "evidence": [ { "id": "G3MXI9", "url": "https://omabrowser.org/oma/group/G3MXI9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P22674-1", "protein_name": "Cyclin-O", "gene_name": "CCNO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK", "length": 350 }, "evidence": [ { "id": "G3MXI9", "url": "https://omabrowser.org/oma/group/G3MXI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "multi-ciliated epithelial cell differentiation", "id": "GO:1903251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903251", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "G3MXI9", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXI9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 351, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXI9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXI9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" }, { "id": "SM01332", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin C-terminal", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 350, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXI9" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 223, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 3, 7 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 328, "end_pos": 330 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXK5-1", "uniprot_ac": "G3MXK5", "uniprot_id": "G3MXK5_BOVIN", "mass": { "chemical_mass": 117589.0, "monoisotopic_mass": 117589.0 }, "refseq": { "ac": "XP_005205045", "name": "espin-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205045" }, "gene_names": [ { "name": "ESPNL", "type": "recommended", "evidence": [ { "id": "G3MXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ] }, { "name": "ESPNL", "type": "synonym", "evidence": [ { "id": "XP_005205045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205045" } ] } ], "protein_names": [ { "name": "Espin like", "type": "synonym", "evidence": [ { "id": "G3MXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXK5/entry#names_and_taxonomy" } ] }, { "name": "espin-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005205045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205045" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ESPNL", "url": "https://www.uniprot.org/uniprotkb/G3MXK5", "locus": { "chromosome": "3", "start_pos": 117465071, "end_pos": 117441584, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010164", "url": "https://www.ensembl.org/id/ENSBTAG00000010164" } ] } } ], "crossref": [ { "id": "G3MXK5", "url": "https://alphafold.ebi.ac.uk/entry/G3MXK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010164", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010164", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524380", "url": "https://www.ncbi.nlm.nih.gov/gene/524380", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NGQLECC", "url": "https://omabrowser.org/oma/group/NGQLECC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BA04", "url": "https://www.orthodb.org/?gene=E1BA04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MXK5", "url": "https://www.orthodb.org/?gene=G3MXK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24153:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24153:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005205045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BA04", "url": "https://www.uniprot.org/uniprotkb/E1BA04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA04-1", "url": "https://www.uniprot.org/uniprotkb/E1BA04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXK5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRALPLLWVPREWLGQGCKARSPRPIPPHPHRLPSALCALIGNRSRELRPILKQEARACVSLGEPAGWPGRRMEEQRALAAAKDGDLATLEQLLEAGTLGPHVTDALGAGLVHHAARAGHLACVRFLVQRAKLPGNQRAHNGATPAHDAAATGGLAELCWLVRHGGCGLQDQDASGVSPLHLAARFGHPVLVDWLLHEGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHRSGVNRRTHSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARGHYSLVVWLVTFTDVGLTARDDDGATVLHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGQMECCQTLLSHRVDPALRDDDGYTAAELAEYHGHRDCAQYLRDSTRPILPQPSVLATPSEAVPGTGWPPTQVPLLMTPPPPPFPPPPLSAARHPPEDGRSGGAGLGSPTPASLSPAWPSQPDQPPLREHTAHTATPRVTASAMAVPTGAETAAGAAPDSLVALQLDGMPLGDLDGLVPTRDERGRPIPEWKRQVMVRKLQARLGTALEAPEAQDDGGHTDAMEQAAWRYSQTHQAILGPFGELLTEDDLVYLEKQIADLQLRRRCQEYENELGRLAAELQALLPAPLVSITVNSRFLSPGPRLEAADTEPRGSEDGASQATPGGQPLPFWCSHVARLVRSLSLLLKGVNGLVQGEERDPLEAQREAHRPAPASPPRSEAQREIQECGVSVRTLRGNFESAPGRPCTPSPGPCELGTQPGSCPRGCWPAPAPPCSGPIGGNPGSGDTEEASDSGISCEEALSEVGAVPGSDLASLRKERIVTLFLSHWKKSAYMPALKTAACRTLEARRSGLRGQEAARGPPMPSPLPSGSPRPSRLWQQRSVIAQLLGHWKAVLAHVPARQLRRLSRRPRGPLSPEQFLPHVDGAPVPYSSLTLDLFMLGYFQLLECDLPAEERKMRHLLCFEVFEHLGAHGWEAARAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSRGRARDAEPGRKSGLTPLRPLPHAGPGGPEPAAQRLGSGPQRGSFNSEDICGYIDRSFAFWKEKEAEMFGFGE", "length": 1096, "header": "tr|G3MXK5-1|G3MXK5_BOVIN Isoform 1 of Espin like OS=Bos taurus OX=9913 GN=ESPNL PE=4 SV=2 CANONICAL=G3MXK5-1" }, "isoforms": [ { "isoform_ac": "E1BA04-1", "url": "https://www.uniprot.org/uniprotkb/E1BA04/entry", "sequence": { "sequence": "MRALPLLWVPREWLGQGCKARSPRPIPPHPHRLPSALCALIGNRSRELRPILKQEARACVSLGEPAGWPGRRMEEQRALAAAKDGDLATLEQLLEAGTLGPHVTDALGAGLVHHAARAGHLACVRFLVQRAKLPGNQRAHNGATPAHDAAATGGLAELCWLVRHGGCGLQDQDASGVSPLHLAARFGHPVLVDWLLHEGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHRSGVNRRTHSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARGHYSLVVWLVTFTDVGLTARDDDGATVLHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGQMECCQTLLSHRVDPALRDDDGYTAAELAEYHGHRDCAQYLRDSTRPVPLLMTPPPPPFPPPPLSAARHPPEDGRSGGAGLGSPTPASLSPAWPSQPDQPPLREHTAHTATPRVTASAMAVPTGAETAAGAAPDSLVALQLDGMPLGDLDGLVPTRDERGRPIPEWKRQVMVRKLQARLGTALEAPEAQDDGGHTDAMEQAAWRYSQTHQAILGPFGELLTEDDLVYLEKQIADLQLRRRCQEYENELGRLAAELQALLPAPLVSITVNSRFLSPGPRLEAADTEPRGSEDGASQATPGGQPLPFWCSHVARLVRSLSLLLKGVNGLVQGEERDPLEAQREAHRPAPASPPRSEAQREIQECGVSVRTLRGNFESAPGRPCTPSPGPCELGTQPGSCPRGCWPAPAPPCSGPIGGNPGSGDTEEASDSGISCEEALSEVGAVPGSDLASLRKERIVTLFLSHWKKSAYMPALKTAACRTLEARRSGLRGQEAARGPPMPSPLPSGSPRPSRLWQQRSVIAQLLGHWKAVLAHVPARQLRRLSRRPRGPLSPEQFLPHVDGAPVPYSSLTLDLFMLGYFQLLECDLPAEERKMRHLLCFEVFEHLGAHGWEAARAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSRGRARDAEPGRKSGLTPLRPLPHAGPGGPEPAAQRLGSGPQRGSFNSEDICGYIDRSFAFWKEKEAEMFGFGE", "length": 1072, "header": "tr|E1BA04-1|G3MXK5_BOVIN Computationally mapped isoform of Espin like OS=Bos taurus OX=9913 GN=ESPNL PE=4 SV=3 CANONICAL=G3MXK5-1" }, "locus": { "chromosome": "3", "start_pos": 117464067, "end_pos": 117441783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013414.5", "url": "https://www.ensembl.org/id/ENSBTAT00000013414.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013414.4", "url": "https://www.ensembl.org/id/ENSBTAP00000013414.4" } ] } }, { "isoform_ac": "G3MXK5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXK5/entry", "sequence": { "sequence": "MRALPLLWVPREWLGQGCKARSPRPIPPHPHRLPSALCALIGNRSRELRPILKQEARACVSLGEPAGWPGRRMEEQRALAAAKDGDLATLEQLLEAGTLGPHVTDALGAGLVHHAARAGHLACVRFLVQRAKLPGNQRAHNGATPAHDAAATGGLAELCWLVRHGGCGLQDQDASGVSPLHLAARFGHPVLVDWLLHEGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHRSGVNRRTHSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARGHYSLVVWLVTFTDVGLTARDDDGATVLHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGQMECCQTLLSHRVDPALRDDDGYTAAELAEYHGHRDCAQYLRDSTRPILPQPSVLATPSEAVPGTGWPPTQVPLLMTPPPPPFPPPPLSAARHPPEDGRSGGAGLGSPTPASLSPAWPSQPDQPPLREHTAHTATPRVTASAMAVPTGAETAAGAAPDSLVALQLDGMPLGDLDGLVPTRDERGRPIPEWKRQVMVRKLQARLGTALEAPEAQDDGGHTDAMEQAAWRYSQTHQAILGPFGELLTEDDLVYLEKQIADLQLRRRCQEYENELGRLAAELQALLPAPLVSITVNSRFLSPGPRLEAADTEPRGSEDGASQATPGGQPLPFWCSHVARLVRSLSLLLKGVNGLVQGEERDPLEAQREAHRPAPASPPRSEAQREIQECGVSVRTLRGNFESAPGRPCTPSPGPCELGTQPGSCPRGCWPAPAPPCSGPIGGNPGSGDTEEASDSGISCEEALSEVGAVPGSDLASLRKERIVTLFLSHWKKSAYMPALKTAACRTLEARRSGLRGQEAARGPPMPSPLPSGSPRPSRLWQQRSVIAQLLGHWKAVLAHVPARQLRRLSRRPRGPLSPEQFLPHVDGAPVPYSSLTLDLFMLGYFQLLECDLPAEERKMRHLLCFEVFEHLGAHGWEAARAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSRGRARDAEPGRKSGLTPLRPLPHAGPGGPEPAAQRLGSGPQRGSFNSEDICGYIDRSFAFWKEKEAEMFGFGE", "length": 1096, "header": "tr|G3MXK5-1|G3MXK5_BOVIN Isoform 1 of Espin like OS=Bos taurus OX=9913 GN=ESPNL PE=4 SV=2 CANONICAL=G3MXK5-1" }, "locus": { "chromosome": "3", "start_pos": 117464067, "end_pos": 117441783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063447.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063447.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054272.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054272.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 411, "start_aa": "Thr", "end_pos": 411, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr411", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 463, "start_aa": "Thr", "end_pos": 463, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr463", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 675, "start_aa": "Thr", "end_pos": 675, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr675", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZGJ2-1", "protein_name": "Espin-like protein", "gene_name": "Espnl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAQQALVASKDGDLATLERLFEAGGLRPDITDDLGAGLVHHATRAGHLDCVKFLVQTAKLPSDQQAHNGATPVHDAAAMGNLAELCWLIRDGGCGLQDQDASGVSPLHLAARFGHPALVEWLLREGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHSSGVNQRTCSGASPLYLACQEGHLHLAQFLVKDCGADVRLRALDGMSSLHAAAARGHYSLVVWLVTFTDIGLTARDNEGATALHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGHMECCQTLLSHHVDPFLRDEDGYTAIDLAEYHGHQDCAQFLREMSRPVPVLMTPPPPPFPPPPLLAAGLPLEEERRGDSGLRSPSSAWPAQPVPREPMACTAPLSVTSSAALQGAEVEPLDSHDGLTTLQLDRLPSGDLDMLVPTQDERGRPIPEWKRQVMVRKLQARLGADHPPEDQDQSQRQDSGPTPAEQATWRYSQTHQAILGPFGELLTEDDLVYLEKQINDLQLRRRCQEYESELGRLAAQLQALLPEPLVSITVNSHFLPRAPGLDDEEGPALAPELEASEEPGKAEPRGQPLPFWCSHIGRLVRSMSLLLKGMNGLAQGEEKPPASVPQDPSKETMAGPSRSEAQREIQECGVSVRTLRGNFEFAPDLPCASNSGPCELGARPGQCLRGCWSAPPQPRGEPMGREPRPGDTEEASDSGISCEEAPSEAGAGPGLDLANLRKERIVMLFLGHWKKSAYTPALRTAACRTLEAQRARSRGPEAASSPRPLSPQPSDSPRLGHLWQQRGIITHLLGTWKAIMAHVPARQLRRLSRRARGPLSPEQFLPHVDGAPVPYNSLSLDLFMLGYFQLLECDLPAEERKMRHLLCFEVFEHLGAHGWEAVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQGPPWDVEPGRKLGLTPLGSLPHAALPGSGPEPASPRLGSNSQQGSFNSGDICGYIDRSFAFWKEKEAEMFNFGE", "length": 999 }, "evidence": [ { "id": "G3MXK5", "url": "https://omabrowser.org/oma/group/G3MXK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UYR4-1", "protein_name": "Espin-like protein", "gene_name": "Espnl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAQQALVASKDGDMATLERLFEAGALRPDITDDLGAGLVHHATRAGHLDCVKFLVQRAKLPGNQQAHNGATPVHDAAATGNLAELCWLVRDAGCGLQDQDASGVSPLHLAARFGHPALVEWLLREGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHSSGVNQRTCSGASPLYLACQEGHLHLAQFLVKDCGADVRLRALDGMSSLHAAAAHGHYSLVVWLVTFTDIGLTARDNEGATALHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGHMECCQTLLSHHVDPFLRDEDGYTAIDLAEYHGHQDCAQFLREMSRPVRVLMTPPPPPFPPPPLLAAKLSLEEERRGDSGLKSPSSATLSPVWPAQPVPREPMACTAPLRVTTPDALQGPEVEARDSRAGLATLQLDGLPAGDLDMLVPTQDERGRPIPEWKRQVMVRKLQARLGADHPPEDQDQSQRQDSGPTAAEQATWRYSQTHQAILGPFGELLTEDDLVYLEKQINDLQLRRRCQEYESELGRLAAQLQALLPEPLVSITVNSHFLPRAPGLEDEEAPVLATELEASEEPGKAEPRGQPLPFWCSHIGRLVRSMSLLLKGMNGLAQGEEKPPSPVPQDLGKETIAGPSRSEAQREIQECGVSVRTLRGNFEFAPDLPCALNSGPCELGVRPGQCLRGCWSAPPQPRGDAMGGEPGPGDTEEASDSGISCEEAPSEAGAGPGLDLASLRKERIVMLFLGHWKKSAYTPALRTAACRTLEAQRARSRGPEAAGSPRPSSPQPSDGPRLGHLWQQRGIITHLLGTWKAIMAHVPARQLRRLSRRERGPLSPEQFLPHVDGAPVPYNSLSLDLFMLGYFQLLECDLPAEERKMRHLLCFEVFEHLGAHGWEAVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQGPPWDVEPGRKLGLTPLGSLPHASLPGSGPEPAVPPRLGSDSQGSSFNSGDICGYIDRSFAFWKEKEAEMFNFGE", "length": 1005 }, "evidence": [ { "id": "G3MXK5", "url": "https://omabrowser.org/oma/group/G3MXK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZVH7-1", "protein_name": "Espin-like protein", "gene_name": "ESPNL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKQRALVAAKDGDVATLERLLEAGALGPGITDALGAGLVHHATRAGHLDCVKFLVQRAQLPGNQRAHNGATPAHDAAATGSLAELCWLVREGGCGLQDQDASGVSPLHLAARFGHPVLVEWLLHEGHSATLETREGARPLHHAAVSGDLTCLKLLTAAHGSSVNRRTRSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARGHYSLVVWLVTFTDIGLTARDNEGATALHFAARGGHTPILDRLLLMGTPILRDSWGGTPLHDAAENGQMECCQTLVSHHVDPSLRDEDGYTAADLAEYHGHRDCAQYLREVAQPVPLLMTPPPPPFPPPPLLATRRSLEDGRRGGPGPGNPSPMSLSPAWPGHPDQPLPREQMTSPAPPRIITSATADPEGTETALAGDTSDGLAALQLDGLPSGDIDGLVPTRDERGQPIPEWKRQVMVRKLQARLGAESSAEAQDNGGSSGPTEQAAWRYSQTHQAILGPFGELLTEDDLVYLEKQIADLQLRRRCQEYESELGRLAAELQALLPEPLVSITVNSHFLPRAPGLEVEEASIPAAEPAGSAEASEVAPGVQPLPFWCSHISRLVRSLSLLLKGVHGLVQGDEKPSTRPLQDTCREASASPPRSEAQRQIQEWGVSVRTLRGNFESASGPLCGFNPGPCEPGAQHRQCLSGCWPALPKPRSGLASGEPRPGDTEEASDSGISCEEVPSEAGAAAGPDLASLRKERIIMLFLSHWRRSAYTPALKTVACRTLGARHAGLRGQEAARSPGPPSPPSEGPRLGHLWQQRSTITHLLGNWKAIMAHVPARQLRRLSRQPRGALSPEQFLPHVDGAPVPYSSLSLDLFMLGYFQLLECDLPAEERKLRHLLCFEVFEHLGTHGWEAVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQRPAWDTEPGRKSGLTLLGPLPHAAVPCSGPEPTAQRLGSRSQQGSFNGEDICGYINRSFAFWKEKEAEMFNFGE", "length": 1005 }, "evidence": [ { "id": "G3MXK5", "url": "https://omabrowser.org/oma/group/G3MXK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ], "pmid": "" }, { "name": "stereocilium tip", "id": "GO:0032426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032426", "evidence": [ { "database": "UniProtKB", "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "G3MXK5", "url": "https://www.uniprot.org/uniprotkb/G3MXK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXK5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1096, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXK5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXK5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 411, 463, 675 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX37-1", "uniprot_ac": "G3MX37", "uniprot_id": "G3MX37_BOVIN", "mass": { "chemical_mass": 107142.0, "monoisotopic_mass": 107142.0 }, "refseq": { "ac": "XP_005218822", "name": "zinc finger CCCH domain-containing protein 18 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218822" }, "gene_names": [ { "name": "ZC3H18", "type": "recommended", "evidence": [ { "id": "G3MX37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ] }, { "name": "ZC3H18", "type": "synonym", "evidence": [ { "id": "XP_005218822", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218822" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 18", "type": "synonym", "evidence": [ { "id": "G3MX37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX37/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH domain-containing protein 18 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005218822", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218822" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZC3H18", "url": "https://www.uniprot.org/uniprotkb/G3MX37", "locus": { "chromosome": "18", "start_pos": 13877305, "end_pos": 13834055, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019520", "url": "https://www.ensembl.org/id/ENSBTAG00000019520" } ] } } ], "crossref": [ { "id": "G3MX37", "url": "https://alphafold.ebi.ac.uk/entry/G3MX37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019520", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523958", "url": "https://www.ncbi.nlm.nih.gov/gene/523958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PYRNYRR", "url": "https://omabrowser.org/oma/group/PYRNYRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BC96", "url": "https://www.orthodb.org/?gene=E1BC96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MX37", "url": "https://www.orthodb.org/?gene=G3MX37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46582:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46582:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005218822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218822", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BC96", "url": "https://www.uniprot.org/uniprotkb/E1BC96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC96-1", "url": "https://www.uniprot.org/uniprotkb/E1BC96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX37-1", "url": "https://www.uniprot.org/uniprotkb/G3MX37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVAESPDRDPRSPEDEEEEQQGLSDDDILRESGSEQDLDAAGGRASDLEDEESVAPGLSQEDEESRSDEDDRDSEAQELSRGPASPPRAEGDCASDLRDEASSVTRDLDEHELDYDEEVPEEPAPGAQEDDAEKAGPEDDEERGEGAPGEEGKVGVRTVEDKEPPEAAKEKRKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKDVVTPLSTPPPISNSIPFRGQVKGNCTWGMNCRFIHPGVNDKGNYSLITKAEPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNYRITRDVRDTALEPYADPYYDYEIERFWRGGQYENFRVQYTEAEPYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDKEREKDKEKPKARSPQPPSRQAEPPKKETVSTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPARAKGEPAPPPTKAGEKLLKKPAPPPALPQAPKTTTAPEPTKPGGDPREARRRERQARSPPRRRTVSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSDDMYADLASPVSSASSRSPTPAQTKKEKGKSKKEDGVKVDKRKRDSSTQPPKPSRTPAGGRSSQQPTTPQQAPPGQPPAATFIAHKEIKLTLLNKATDKGSRKRYEPSDKDRQSPPPAKRANLSPDRGSRDRKSGGRVSSPKPERQRGQNSKAPSAPTDRKRPLSPQSKSSSKVTSVPGKASDTSTTATAGTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKV", "length": 960, "header": "tr|G3MX37-1|G3MX37_BOVIN Isoform 1 of Zinc finger CCCH-type containing 18 OS=Bos taurus OX=9913 GN=ZC3H18 PE=4 SV=2 CANONICAL=G3MX37-1" }, "isoforms": [ { "isoform_ac": "E1BC96-1", "url": "https://www.uniprot.org/uniprotkb/E1BC96/entry", "sequence": { "sequence": "MDVAESPDRDPRSPEDEEEEQQGLSDDDILRESGSEQDLDAAGGRASDLEDEESVAPGLSQEDEESRSDEDDRDSEAQELSRGPASPPRAEGDCASDLRDEASSVTRDLDEHELDYDEEVPEEPAPGAQEDDAEKAGPEDDEERGEGAPGEEGKVGVRTVEDKEPPEAAKEKRKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKAEPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNYRITRDVRDTALEPYADPYYDYEIERFWRGGQYENFRVQYTEAEPYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDKEREKDKEKPKARSPQPPSRQAEPPKKETVSTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSSRSRSFSSSPSPSPTPSPHRPARAKGEPAPPPTKAGEKLLKKPAPPPALPQAPKTTTAPEPTKPGGDPREARRRERQARSPPRRRTVSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSDDMYADLASPVSSASSRSPTPAQTKKEKGKSKKEDGVKVDKRKRDSSTQPPKPSRTPAGGRSSQQPTTPQQAPPGQPPAATFIAHKEIKLTLLNKATDKGSRKRYEPSDKDRQSPPPAKRANLSPDRGSRDRKSGGRVSSPKPERQRGQNSKAPSAPTDRKRPLSPQSKSSSKVTSVPGKASDTSTTATAGTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKV", "length": 938, "header": "tr|E1BC96-1|G3MX37_BOVIN Computationally mapped isoform of Zinc finger CCCH-type containing 18 OS=Bos taurus OX=9913 GN=ZC3H18 PE=4 SV=4 CANONICAL=G3MX37-1" }, "locus": { "chromosome": "18", "start_pos": 13876704, "end_pos": 13840529, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061317.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061317.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053710.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053710.4" } ] } }, { "isoform_ac": "G3MX37-1", "url": "https://www.uniprot.org/uniprotkb/G3MX37/entry", "sequence": { "sequence": "MDVAESPDRDPRSPEDEEEEQQGLSDDDILRESGSEQDLDAAGGRASDLEDEESVAPGLSQEDEESRSDEDDRDSEAQELSRGPASPPRAEGDCASDLRDEASSVTRDLDEHELDYDEEVPEEPAPGAQEDDAEKAGPEDDEERGEGAPGEEGKVGVRTVEDKEPPEAAKEKRKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKDVVTPLSTPPPISNSIPFRGQVKGNCTWGMNCRFIHPGVNDKGNYSLITKAEPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNYRITRDVRDTALEPYADPYYDYEIERFWRGGQYENFRVQYTEAEPYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDKEREKDKEKPKARSPQPPSRQAEPPKKETVSTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPARAKGEPAPPPTKAGEKLLKKPAPPPALPQAPKTTTAPEPTKPGGDPREARRRERQARSPPRRRTVSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSDDMYADLASPVSSASSRSPTPAQTKKEKGKSKKEDGVKVDKRKRDSSTQPPKPSRTPAGGRSSQQPTTPQQAPPGQPPAATFIAHKEIKLTLLNKATDKGSRKRYEPSDKDRQSPPPAKRANLSPDRGSRDRKSGGRVSSPKPERQRGQNSKAPSAPTDRKRPLSPQSKSSSKVTSVPGKASDTSTTATAGTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKV", "length": 960, "header": "tr|G3MX37-1|G3MX37_BOVIN Isoform 1 of Zinc finger CCCH-type containing 18 OS=Bos taurus OX=9913 GN=ZC3H18 PE=4 SV=2 CANONICAL=G3MX37-1" }, "locus": { "chromosome": "18", "start_pos": 13876704, "end_pos": 13840529, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065249.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065249.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054096.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054096.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 618, "start_aa": "Thr", "end_pos": 618, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr618", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 752, "start_aa": "Thr", "end_pos": 752, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr752", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FTE6-1", "protein_name": "Zinc finger CCCH domain-containing protein 18 isoform X1", "gene_name": "Zc3h18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDVAESPELDPRSPEDEEQPALSDDDILRETGSEQDLDGAGERASDLEDEENATRVQSQEETHSDEEDRASEPKSQDQDSEAHELSRGPAGSLCEEGDDVEEDQTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAAQEEEAEKVGAEDEEEKGEGAPGEEGKPDVQSVGEKEPTEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKDVVTPLSTLLPPIPNSIPLRGQVKGILPVVLIMQLMITNPTNNHKLKSLFISGPNRHMNLLMPTAAVSCWCLHMLAELNLGHWTWGLWPAGNCTWGMNCRFIHPGVNDKGNYSLITKTEPFPPNGAPPLGPHPLMPANPWGAPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDDREFDKENEVFRDWNSRVPRDVRDTILEPYADPYYDYDIERFWRGGQYENFRVQYTEAEPYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDRDKDREKDKEKPKPRSPQPPSRQAEPPKKETTSVGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPPVRTKGEPAPPPGKAGEKSVKKPAPPPAPPQTTKTTAPAPEPAKPGDLREARRKERQTRTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSVHSVDSEDMYADLASPVSSASSRSPTPAQTKKERGKSKKEDGVREEKRKRDPSTQPPKSSKAPTGGKSSQQSAAPQQTAPGQPQQGSFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPAKKANLTPDRGSRDRKSGGKMGSPKPERQRGQNAKAPAAQADRKRPLSPQSKSSSKVTSVPGKATDTATAGTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKV", "length": 1038 }, "evidence": [ { "id": "G3MX37", "url": "https://omabrowser.org/oma/group/G3MX37/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0P678-1", "protein_name": "Zinc finger CCCH domain-containing protein 18", "gene_name": "Zc3h18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVAESPELDPHSPEDEEQPALSDDDILRESGSEQDLDGAGERASDLEEEENATRVQSQEETRSDEEDRASEPKSQDQDSEAHELSRGPAGSPCEEGDDVEEDGTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAAQEEEAEKAGAEEEEEKGEGAPGEEGKPDVQSVGEQEPTEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMSCRFIHPGVNDKGNYSLITKAEPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDDREFDKENEVFRDWNSRVPRDVRDTTLEPYADPYYDYEIERFWRGGQYENFRVQYTEAEPYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDRDKDREKDKEKPKPRSPQPPSRQAEPPKKESTSVGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPPVRTKGEPAPPPGKAGEKSIKKPAPPPAPPQATKTTAPGPEPAKPGDLREARRKERQTRTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSVHSVDSDDMYADLASPVSSASSRSPTPAQTKKERGKSKKEDGVREEKRRRDPSAQPPKSSKAPAGGKASQQAAAPQPAVPGQPQQGSFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPAKKANLSPDRGSRDRKSGGRMGSPKPERQRGQNAKAPAAPADRKRPLSPQSKGSSKVTSVPGKATDTATAGTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKV", "length": 948 }, "evidence": [ { "id": "G3MX37", "url": "https://omabrowser.org/oma/group/G3MX37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1LUE5-1", "protein_name": "Zinc finger CCCH domain-containing protein 18", "gene_name": "zc3h18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDTPESPTQSPQSPEEEEKGLSDNELLESPESPAEADKGVSDSELLNDDENEVPEHGGDSDSEDRDRQPAGREDPEELSDVEDYKLDREEREDIHQQEGALRVQEIAQKAIKSPEEEILETPRSPDPVSPAAEHERPFTPAEEERGDDDEEEEEDETTTKSGLGQAELEEEEDEEEERRRRRRAAMVVSDLKDESSVSRDLDEHELDYDEEVPEEPSAAAPEEDEPEKPAVGEDGEDEEEEDEEEEKRRKRKERKPILPPDNRDTPLRKSEDSREGGRRDSFRDKKKEEDDGEIDEGEIDDDDLEEGEVKDPMDRKIRPRPICRFFMKGSFVTMYGNVKFFFFKSYLVFLTGNCTWGMICRFIHPGVNDKGNYSLISKPDPFSPNGAPPGGAAGGGPHPLMPANPWGAPAVEELPPPPPPLDPPVESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDDRDFDKENDFFRERGGYRITREIRDAGSDPYGDPYYDYEMEAFWRGGQYENFRVQYTETPLPYYPDRERERDPRERHRERERERERDHRERERRQREREREREREREKDSRRRKDEWDRDRLKRDEKEGRPRERPLREPREKKDEKEKTLKPRSPTNMPPRGPMEPPTKKDMLSVTKRPDEWNDPWCRSKSPRRRPGFMGSPPRGRRRHRPSGSSVSLSNSSRSSSRSSSFTGSGSSRSRSRSRSSSMSSYSSHSSQHSSFSGSRSRSGSFSSSPSPSPSAQRNANKNKAEQPPAAAKGPPLKPGALPPPRRDKGPPKVMPSPSLPEQPGKPPKPITETVKPPNPRPPGRPPGPREPREPPNMREGRKKERQQHNPPRRRTVSGSVSGSSYSGSSSRSRSRSSSASASRSGSHKSRSLSVSSVSSVSSASSSSSSVRSADSDDMYADLASPVSSASSRSPTPGHPRKDRGPPRERGPNKERGKPPKKDEPFKDERKRVDPSGLPSKASSDMPRSGNRGHPMHPPPMGPPGGYGSHKDIKLTLLNKQQTDRSNRKRYFPSDKERPPSPLRKRMAMSPDGGRDRRMPGRPPMSPRMERPKGQGPRPMPSQGERKRPLSPPAKSSGKGPAAASAAKPPAPGAGSGSASGSAPGKPSSTLSRREELLKQLKAVEDAIARKRAKIPGK", "length": 1148 }, "evidence": [ { "id": "G3MX37", "url": "https://omabrowser.org/oma/group/G3MX37/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6TQE1-1", "protein_name": "Zinc finger CCCH domain-containing protein 18", "gene_name": "Zc3h18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAESPELEPHSPDEEQPALSDDDILRESGSEQDLDGAGERASDLEEEENATRVQSQEEIHSDEEDQASEPKSQDQDSEAHELSRGPAGSPCEEGDDAEEDGTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAAQEEEAEKAGAEEEEEKGEGAPGEEGKPDVQSVGEKEPTEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKAEPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDDREFDKENEVFRDWNSRVPRDVRDTTLEPYADPYYDYEIERFWRGGQYENFRVQYTEAEPYHNYRDRERERERENRQRERERDRERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDRDKDRDKDKEKPKPRSPQPPSRQAEPPKKETASVGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRRSSFSGSRSRSRSFSSSPSPSPTPSPHRPPVRTKGEPAPPPGKAGEKSIKKPAPPPAPPQATKTTAPAPEPAKPGDLREARRKERQTRTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSVHSVDSDDMYADLASPVSSASSRSPTPAQTKKERGKSKKEDGVREEKRKRDPSAQPPKSSKAPAGGKASQQAAAPQQAAPGQPQQGSFVAHKEIKLTLLNKAAEKGSRKRYEPSDKDRQSPPAKKANLSPDRGSRDRKSGGRMGSPKPERQRGQNAKAPAAPADRKRPLSPQSKSSSKVTSVPGKATDTATAGTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKV", "length": 947 }, "evidence": [ { "id": "G3MX37", "url": "https://omabrowser.org/oma/group/G3MX37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86VM9-1", "protein_name": "Zinc finger CCCH domain-containing protein 18", "gene_name": "ZC3H18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKA", "length": 953 }, "evidence": [ { "id": "G3MX37", "url": "https://omabrowser.org/oma/group/G3MX37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W3R9-1", "protein_name": "C3H1-type domain-containing protein", "gene_name": "Dmel\\CG1677", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLDMESDDSHASSASNSSESRSNSPTNDKDEVVADHGGESPGGGGDPILDRSDRAPSTSSSSSNSSSSSNRSDLSKKQKKSSSSSSGSGSGSGSSSSSGSSSEDEGDQEPEQEVQRLSEQQREQQQHSPINERESESAAGTPVNADQPGSPNAKSQPSSFLSSVRSRSVSPQLYNQAAVDLNISHDDLSDVSDIEGEEKRTSSKNSMRPADENEDGAISNDSLPTLGEEDEVEQKQSTPNGKASSGDEKEPFAKETHTDDASNGLAPATALQEDLVKTHDDDALDFEAEEGECPEQAKEPSPMESTANETNQTKSTTKVSQDEGDDDGEVDKDGDDKDGDDKDTRKDGAGNGCLEDGAGNDSRKDDAGNGCLEEGEEEKDIVSVSTSSSQEKVEEGELEEGEVSDEDEKRPEETEPKPVCRFYTRGQCTWGMSCRFLHPGVTDKGNYTMFDNVIRPVPMQGGSTGASAPAAPSSTAAPRAGGSAYSSHASATADYHDYRTERPLHHRPPLLHAPSIYGAPVHDARTLLPDGAPVVVENAWERGLRTAKEMMRKANKRKEQDMDFEDKKMNLTLSPDEMEKDSYYLKDRGGSSARSPPPPSANVREQPLNPLSMPLSMHPHAVAHANPRALLPLQYSVYGPPPDRYGRPQYMPPQYDDVDAYGRMTRYRELPPHRMPHYEDDRRSRPTREVIVQRVEAAGRGDEWSDPWMRSKSVGRGSYEREDRRRRDRRSYSSNSSYSTSNSSQSDSSSDSSRSSSPSDHKRRYGSHKLATATATSRRHGGRAARSPSQIPRRPRRTSKGSLSPSYKRPAVDKRGVGHSPSSKRKKLSSPAPKKFDKLRRRRSSSSSDSDSSDTSYSDSESGSSSSDSSSGSRETPQKRVRATDKALNERKLISKPAEQSTKKRSPISIEIKKTSNMVGVSALASASNSADSDAEKDHDNGKDKEKDHVKEKDKDCKEKDKDKDGMKDKEGKKSRREELLKQLRAVEDAIAKKRSKLN", "length": 1000 }, "evidence": [ { "id": "G3MX37", "url": "https://omabrowser.org/oma/group/G3MX37/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ], "pmid": "" }, { "name": "mRNA cap binding complex binding", "id": "GO:0140262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140262", "evidence": [ { "database": "UniProtKB", "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA destabilization", "id": "GO:0050779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050779", "evidence": [ { "database": "UniProtKB", "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "G3MX37", "url": "https://www.uniprot.org/uniprotkb/G3MX37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 854, "end_pos": 856, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MX37-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 960, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MX37-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MX37" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MX37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX37" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 254, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 618, 752 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 854, "end_pos": 856 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYZ0-1", "uniprot_ac": "G3MYZ0", "uniprot_id": "G3MYZ0_BOVIN", "mass": { "chemical_mass": 44239.0, "monoisotopic_mass": 44239.0 }, "refseq": {}, "gene_names": [ { "name": "OVOL2", "type": "recommended", "evidence": [ { "id": "G3MYZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ] } ], "protein_names": [ { "name": "Ovo like zinc finger 2", "type": "synonym", "evidence": [ { "id": "G3MYZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OVOL2", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0", "locus": { "chromosome": "13", "start_pos": 38271778, "end_pos": 38301193, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008410", "url": "https://www.ensembl.org/id/ENSBTAG00000008410" } ] } } ], "crossref": [ { "id": "G3MYZ0", "url": "https://alphafold.ebi.ac.uk/entry/G3MYZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008410", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008410", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BDB8", "url": "https://www.orthodb.org/?gene=E1BDB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYZ0", "url": "https://www.orthodb.org/?gene=G3MYZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10032:SF193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10032:SF193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BDB8", "url": "https://www.uniprot.org/uniprotkb/E1BDB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDB8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYZ0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SRSGPREWKFGARCPQPRLALVPRGHGNLERGADAPHRPPGPQACSGGRVRGSIAHPRGIAHLARCPGPGRGGGGTARRSNCCGRPGLTPRVCVSGRGPRSAVGLGRLLHDPPEDCRSDGGSSTGGGSSSAGEPGGAESSSSPRGPERETPEPGDGEGPDGHLAAKQRPVARSKIKSPPPTQPLGIVGHSLSRRPSALSWVELPRLPAQRYPLPPRLSLNPLTHSQPEPGSGVFRNHMTPAPSQFTTGTCGDAAMHTCDLCGKAFRLQRMLNRHLKCHSQVKRHLCSFCGKGFNDTFDLKRHVRTHTGIRPYKCDVCHKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNGAHPGSAFLKKTSKKLAALLQNKMTSSLQGNANLSEEEEK", "length": 411, "header": "tr|G3MYZ0-1|G3MYZ0_BOVIN Isoform 1 of Ovo like zinc finger 2 OS=Bos taurus OX=9913 GN=OVOL2 PE=3 SV=3 CANONICAL=G3MYZ0-1" }, "isoforms": [ { "isoform_ac": "E1BDB8-1", "url": "https://www.uniprot.org/uniprotkb/E1BDB8/entry", "sequence": { "sequence": "MIHKWGATWTRGPQSGERAPTMPKVFLVKRRSLGVSVRSWDELPDEERADTYIPVGLGRLLHDPPEDCRSDGGSSTGGGSSSAGEPGGAESSSSPRGPERETPEPGDGEGPDGHLAAKQRPVARSKIKFTTGTCGDAAMHTCDLCGKAFRLQRMLNRHLKCHSQVKRHLCSFCGKGFNDTFDLKRHVRTHTGIRPYKCDVCHKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNGAHPGSAFLKKTSKKLAALLQNKMTSSLQGNANLSEEEEK", "length": 295, "header": "tr|E1BDB8-1|G3MYZ0_BOVIN Computationally mapped isoform of Ovo like zinc finger 2 OS=Bos taurus OX=9913 GN=OVOL2 PE=3 SV=2 CANONICAL=G3MYZ0-1" }, "locus": { "chromosome": "13", "start_pos": 38301076, "end_pos": 38272161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011067.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011067.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011067.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011067.6" } ] } }, { "isoform_ac": "G3MYZ0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0/entry", "sequence": { "sequence": "SRSGPREWKFGARCPQPRLALVPRGHGNLERGADAPHRPPGPQACSGGRVRGSIAHPRGIAHLARCPGPGRGGGGTARRSNCCGRPGLTPRVCVSGRGPRSAVGLGRLLHDPPEDCRSDGGSSTGGGSSSAGEPGGAESSSSPRGPERETPEPGDGEGPDGHLAAKQRPVARSKIKSPPPTQPLGIVGHSLSRRPSALSWVELPRLPAQRYPLPPRLSLNPLTHSQPEPGSGVFRNHMTPAPSQFTTGTCGDAAMHTCDLCGKAFRLQRMLNRHLKCHSQVKRHLCSFCGKGFNDTFDLKRHVRTHTGIRPYKCDVCHKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNGAHPGSAFLKKTSKKLAALLQNKMTSSLQGNANLSEEEEK", "length": 411, "header": "tr|G3MYZ0-1|G3MYZ0_BOVIN Isoform 1 of Ovo like zinc finger 2 OS=Bos taurus OX=9913 GN=OVOL2 PE=3 SV=3 CANONICAL=G3MYZ0-1" }, "locus": { "chromosome": "13", "start_pos": 38299962, "end_pos": 38272161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000062966.3", "url": "https://www.ensembl.org/id/ENSBTAT00000062966.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054779.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054779.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "epidermal cell differentiation", "id": "GO:0009913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009913", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "regulation of keratinocyte differentiation", "id": "GO:0045616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045616", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "regulation of keratinocyte proliferation", "id": "GO:0010837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010837", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "negative regulation of multicellular organismal process", "id": "GO:0051241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051241", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3MYZ0", "url": "https://www.uniprot.org/uniprotkb/G3MYZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYZ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 411, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYZ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYZ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ 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"header": "tr|G3N2J0-1|G3N2J0_BOVIN Isoform 1 of Coiled-coil domain containing 62 OS=Bos taurus OX=9913 GN=CCDC62 PE=4 SV=3 CANONICAL=G3N2J0-1" }, "locus": { "chromosome": "17", "start_pos": 52745526, "end_pos": 52704984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065548.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065548.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056105.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056105.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "G3N2J0", "url": "https://www.uniprot.org/uniprotkb/G3N2J0" } ], "pmid": "" }, { "name": "nuclear 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Peptide", "id": "ENSBTAP00000002416.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002416.6" } ] } }, { "isoform_ac": "F6RL89-1", "url": "https://www.uniprot.org/uniprotkb/F6RL89/entry", "sequence": { "sequence": "MGLVALVLTSLAISTAWAGLPPSPPIVDTAQGRVLGKYVSLKGFAQPVGVFLGIPFAKPPLGSLRFAPPQPAEPWTFVKNTTSYSPMCSQNAVLVEMTSDLISNGMETVKTKFSEDCLYLNIYTPADLTKRSRLPVMVWIHGGALLTGGASSCDGLVLSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQENIANFGGDPGSVTIFGGSAGAESVSVLVLSPLAKNLFHRAISESGVALIPGLVKKDSKAEAKRIAAFAGCKTITSAVLVHCLRQKTEDELLEITQKMNFFTLNFLGDPTKTYPFLPTVVDGVLLPKMPEEMLAEKNFNTVPYIVGINKQEFGWILPLQLMGFPLTAGKMDQEMATSFVWKSYPILNIPEELAPVATDKYLGGTHDPVQKKDLLLDLIADGLFGVPSVNTARYHRDAGVPTYMYEFQYRPRFSSELKSKTVIGDHGDEQSSVFGIPVLQDGASEEEINLSKMMMKFWANFARNGNPNGKGLPHWPAYDQKEGYLQIGVNTQAAEKLKSEKVAFWNELLSQEATKKAPRSKHVEL", "length": 567, "header": "tr|F6RL89-1|F6RL89_BOVIN Isoform 1 of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=BREH1 PE=1 SV=1 CANONICAL=F6RL89-1" }, "locus": { "chromosome": "18", "start_pos": 24771807, "end_pos": 24745188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032460.5", "url": "https://www.ensembl.org/id/ENSBTAT00000032460.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032392.5", "url": "https://www.ensembl.org/id/ENSBTAP00000032392.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F6RL89", "url": "https://www.uniprot.org/uniprotkb/F6RL89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QW25-1", "uniprot_ac": "F6QW25", "uniprot_id": "F6QW25_BOVIN", "mass": { "chemical_mass": 49899.0, "monoisotopic_mass": 49899.0 }, "refseq": {}, "gene_names": [ { "name": "ALG3", "type": "recommended", "evidence": [ { "id": "F6QW25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ] } ], "protein_names": [ { "name": "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase", "type": "recommended", "evidence": [ { "id": "F6QW25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW25/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.258", "type": "synonym", "evidence": [ { "id": "F6QW25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW25/entry#names_and_taxonomy" } ] }, { "name": "Dol-P-Man-dependent alpha(1-3)-mannosyltransferase", "type": "synonym", "evidence": [ { "id": "F6QW25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW25/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first dolichyl beta-D-mannosyl phosphate derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-dolichol to produce Man(6)GlcNAc(2)-PP-dolichol.", "evidence": [ { "database": "UniProtKB", "id": "F6QW25", "url": "https://www.uniprot.org/uniprotkb/F6QW25#function" }, { "database": "UniProtKB", "id": "RU364047", "url": "https://www.uniprot.org/uniprotkb/RU364047#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QW25", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ALG3", "url": "https://www.uniprot.org/uniprotkb/F6QW25", "locus": { "chromosome": "1", "start_pos": 82933236, "end_pos": 82927910, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005652", "url": "https://www.ensembl.org/id/ENSBTAG00000005652" } ] } } ], "crossref": [ { "id": "F6QW25", "url": "https://alphafold.ebi.ac.uk/entry/F6QW25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005652", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005652", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6QW25", "url": "https://www.orthodb.org/?gene=F6QW25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12646:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12646:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-446193", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446193", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29527", "url": "https://www.rhea-db.org/rhea/29527", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6QW25", "url": "https://www.uniprot.org/uniprotkb/F6QW25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QW25-1", "url": "https://www.uniprot.org/uniprotkb/F6QW25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGLRKRGRAGPATRAAGLCGQWLRRAWQERRLLLLEPRYTLLVAACLCLAEVGITFWVIHRVAYTEIDWKAYMAEVEGVINGTYDYTQLQGDTGPLVYPAGFVYIFMGLYYATDRGADIRMAQHIFAVLYLATLLLVFLIYHQTCKVPPFVFFFMCCASYRVHSIFVLRLFNDPVAMVLLFLSVNLLLAQRWSWGCCCFSLAVSVKMSVLLFAPGLLFLLLTKFGLRGALPKLGICAVLQVVLGLPFLLKNPVGYLSRSFDLGRQFLFRWTVNWRFLPEALFLHRAFHLALLTAHLTVLLLFALCRWHRTGEGILSLLKDPSKRKVPPQPLTPNHIVSTLFTSNFIGICFSRSLHYQFYVWYFHTLPYLLWATPARWLTHLLRLLVLGLIELSWNTYPSTSCSSAALHACHAVILLQLWLGPQPFPKTIPHSKKAH", "length": 438, "header": "tr|F6QW25-1|F6QW25_BOVIN Isoform 1 of Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Bos taurus OX=9913 GN=ALG3 PE=4 SV=2 CANONICAL=F6QW25-1" }, "isoforms": [ { "isoform_ac": "F6QW25-1", "url": "https://www.uniprot.org/uniprotkb/F6QW25/entry", "sequence": { "sequence": "MAAGLRKRGRAGPATRAAGLCGQWLRRAWQERRLLLLEPRYTLLVAACLCLAEVGITFWVIHRVAYTEIDWKAYMAEVEGVINGTYDYTQLQGDTGPLVYPAGFVYIFMGLYYATDRGADIRMAQHIFAVLYLATLLLVFLIYHQTCKVPPFVFFFMCCASYRVHSIFVLRLFNDPVAMVLLFLSVNLLLAQRWSWGCCCFSLAVSVKMSVLLFAPGLLFLLLTKFGLRGALPKLGICAVLQVVLGLPFLLKNPVGYLSRSFDLGRQFLFRWTVNWRFLPEALFLHRAFHLALLTAHLTVLLLFALCRWHRTGEGILSLLKDPSKRKVPPQPLTPNHIVSTLFTSNFIGICFSRSLHYQFYVWYFHTLPYLLWATPARWLTHLLRLLVLGLIELSWNTYPSTSCSSAALHACHAVILLQLWLGPQPFPKTIPHSKKAH", "length": 438, "header": "tr|F6QW25-1|F6QW25_BOVIN Isoform 1 of Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Bos taurus OX=9913 GN=ALG3 PE=4 SV=2 CANONICAL=F6QW25-1" }, "locus": { "chromosome": "1", "start_pos": 82933074, "end_pos": 82927922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032212.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032212.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032149.5", "url": "https://www.ensembl.org/id/ENSBTAP00000032149.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-446193", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446193", "resource": "Reactome", "description": "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6QW25", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6QW25", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "F6QW25", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity", "id": "GO:0052925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052925", "evidence": [ { "database": "UniProtKB", "id": "F6QW25", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29527", "name": "", "equation": "an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QW25-1" ], "evidence": [ { "id": "29527", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29527" } ] }, { "id": "R-BTA-446188", "name": "ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-449298" ], "output_participant_list": [ "R-ALL-449315" ], "enzyme_list": [ "F6QW25-1" ], "evidence": [ { "id": "R-BTA-446188", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446188" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-449298", "participant_name": "(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "37633", "database": "ChEBI", "url": "" }, { "id": "G59406KS", "database": "GlyTouCan", "url": "" }, { "id": "C05864", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-449315", "participant_name": "(GlcNAc)2 (Man)6 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "53023", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F6QW25", "gene_name": "ALG3", "activity": [ { "ec_number": "2.4.1.258", "activity": "an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+).", "evidence": [ { "id": "F6QW25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ] }, { "ec_number": "2.4.1.258", "activity": "", "evidence": [ { "id": "F6QW25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW25" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QW25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 438, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QW25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QW25" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00028MO", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00085FR", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00152UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00247PL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00330GX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00348IY", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G00349CA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00433KW", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00471UP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00487XO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00582VL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00588HO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00629YK", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00645SW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00706VT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00842OY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00855BY", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00876GU", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00883ZT", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G00910RZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01079TS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01220PX", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01255GI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01260RY", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01359SY", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01416SG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01621RQ", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01657DW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01727MH", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01914VS", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01919UV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G01946CN", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01954TO", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G01954ZH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G01999JH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G02081QK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G02229WQ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G02238VC", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G02526NN", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G02791JM", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G02835AW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G02945KQ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G03019AY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G03056DW", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03067GR", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03275SD", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G03308GV", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G03459AF", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G03595ET", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G03605BS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G03606VC", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G03609WM", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G03652TR", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G03695SF", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G03744SM", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G03793TZ", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G03820FM", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03940QB", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03964XM", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03974HM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G04109RU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04146DI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04207EW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04216GB", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G04220HB", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G04261UG", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04353BC", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G04445KN", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04570XN", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G04576KS", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04667JP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04675YX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04681PT", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G04689DA", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G04705FR", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04792UK", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G04846SY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04851FX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04921DS", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G04930QT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G04987NY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G05140WY", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G05171CQ", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G05421OW", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G05444WW", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G05454SP", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G05510NY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G05763EW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G05794RZ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06024BE", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G06054EC", "type": "N-linked", "subtype": "High mannose" }, { "glytoucan_ac": "G06100NA", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06131JN", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06364YO", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G06371NP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G06374YY", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06463RK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06553ZS", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G06673YV", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06675AE", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G06705NF", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06729UK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G06768XI", "type": "N-linked", "subtype": "High mannose" }, { 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synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223#function" }, { "database": "UniProtKB", "id": "ARBA00054097", "url": "https://www.uniprot.org/uniprotkb/ARBA00054097#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RFK", "url": "https://www.uniprot.org/uniprotkb/F6R223", "locus": { "chromosome": "8", "start_pos": 52453494, "end_pos": 52459617, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019345", "url": "https://www.ensembl.org/id/ENSBTAG00000019345" } ] } } ], "crossref": [ { "id": "F6R223", "url": "https://alphafold.ebi.ac.uk/entry/F6R223", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019345", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019345", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR015865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6R223", "url": "https://www.orthodb.org/?gene=F6R223", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22749", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22749", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22749:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22749:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196843", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "14357", "url": "https://www.rhea-db.org/rhea/14357", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R223-1", "url": "https://www.uniprot.org/uniprotkb/F6R223-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KGKGGKKHLGVSENSAFHSPEAEKNVSLPQIPTPGIHPRKGKAAIPHLRLGAGLRKPNGRRGALLEQCAQARGTRWAGVPPAPARLCRAPRPHPYLVPQSPASRSPDAASESSGTFCWVSGRETLAAACSPHRSAVGHPSARPPGGPAELPHVSPGWSGGQGTASTAAPPDSRSGPQPEPEADGVMRQLPYFCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADISTGIYYGWASVGNGDVHKMVVSIGWNPYYKNTKKSMETHIMHTFKEDFYGEILKVAIVGYLRPEKNFDSLEALISAIQGDIEEAKKRLDLPEHLKLKEDKFFQVPKSKIMNGH", "length": 340, "header": "tr|F6R223-1|F6R223_BOVIN Isoform 1 of Riboflavin kinase OS=Bos taurus OX=9913 GN=RFK PE=4 SV=2 CANONICAL=F6R223-1" }, "isoforms": [ { "isoform_ac": "F6R223-1", "url": "https://www.uniprot.org/uniprotkb/F6R223/entry", "sequence": { "sequence": "KGKGGKKHLGVSENSAFHSPEAEKNVSLPQIPTPGIHPRKGKAAIPHLRLGAGLRKPNGRRGALLEQCAQARGTRWAGVPPAPARLCRAPRPHPYLVPQSPASRSPDAASESSGTFCWVSGRETLAAACSPHRSAVGHPSARPPGGPAELPHVSPGWSGGQGTASTAAPPDSRSGPQPEPEADGVMRQLPYFCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADISTGIYYGWASVGNGDVHKMVVSIGWNPYYKNTKKSMETHIMHTFKEDFYGEILKVAIVGYLRPEKNFDSLEALISAIQGDIEEAKKRLDLPEHLKLKEDKFFQVPKSKIMNGH", "length": 340, "header": "tr|F6R223-1|F6R223_BOVIN Isoform 1 of Riboflavin kinase OS=Bos taurus OX=9913 GN=RFK PE=4 SV=2 CANONICAL=F6R223-1" }, "locus": { "chromosome": "8", "start_pos": 52459418, "end_pos": 52454671, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025762.4", "url": "https://www.ensembl.org/id/ENSBTAT00000025762.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025762.4", "url": "https://www.ensembl.org/id/ENSBTAP00000025762.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-196843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196843", "resource": "Reactome", "description": "Vitamin B2 (riboflavin) metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "pmid": "" }, { "name": "riboflavin kinase activity", "id": "GO:0008531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008531", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "riboflavin biosynthetic process", "id": "GO:0009231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009231", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "pmid": "" }, { "name": "FMN biosynthetic process", "id": "GO:0009398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009398", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "pmid": "" }, { "name": "riboflavin metabolic process", "id": "GO:0006771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006771", "evidence": [ { "database": "UniProtKB", "id": "F6R223", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14357", "name": "", "equation": "riboflavin + ATP = FMN + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6R223-1" ], "evidence": [ { "id": "14357", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14357" } ] }, { "id": "R-BTA-196964", "name": "RFK:Mg2+ phosphorylates RIB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-196931" ], "output_participant_list": [], "enzyme_list": [ "F6R223-1" ], "evidence": [ { "id": "R-BTA-196964", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196964" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-196931", "participant_name": "RIB [cytosol]", "crossref": [ { "id": "57986", "database": "ChEBI", "url": "" }, { "id": "ZINC000002036848", "database": "ZINC", "url": "" }, { "id": "C00255", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F6R223", "gene_name": "RFK", "activity": [ { "ec_number": "2.7.1.26", "activity": "riboflavin + ATP = FMN + ADP + H(+).", "evidence": [ { "id": "F6R223", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ] }, { "ec_number": "2.7.1.26", "activity": "", "evidence": [ { "id": "F6R223", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R223" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R223-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 340, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R223-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R223" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R223", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R223" }, { "id": "SM00904", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Riboflavin kinase", "eco_id": "ECO_0000259", "start_pos": 186, "end_pos": 316, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.26", "ec_name": "riboflavin + ATP = FMN + ADP + H(+).", "evidence": [ { "id": "2.7.1.26", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.26" }, { "id": "2.7.1.26", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.26" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 33 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R253-1", "uniprot_ac": "F6R253", "uniprot_id": "F6R253_BOVIN", "mass": { "chemical_mass": 42041.0, "monoisotopic_mass": 42041.0 }, "refseq": {}, "gene_names": [ { "name": "LOC614494", "type": "recommended", "evidence": [ { "id": "F6R253", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R253" } ] } ], "protein_names": [ { "name": "Acyltransferase", "type": "recommended", "evidence": [ { "id": "F6R253", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R253/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.-", "type": "synonym", "evidence": [ { "id": "F6R253", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R253/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R253", "url": "https://www.uniprot.org/uniprotkb/F6R253" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC614494", "url": "https://www.uniprot.org/uniprotkb/F6R253", "locus": {} } ], "crossref": [ { "id": "F6R253", "url": "https://alphafold.ebi.ac.uk/entry/F6R253", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12317:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12317:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03982", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03982", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6R253", "url": "https://www.uniprot.org/uniprotkb/F6R253", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R253-1", "url": "https://www.uniprot.org/uniprotkb/F6R253-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRQSLAAANTSKCLSPQQSSEKPPEPRGASMVEFAPLFVPLERRLQTFAVLYWIFCFIVLPPLCLVVFIGLLFTRFWLFNILYVIWLYLDQNRPRQGGSHNKFLKRWVLWKYMKDYFPITLVKTTELDPSRNYLAAFHPHGLLSVGAFTNMCTDSTGFSSLFPGIRPHLTTINIYFRIPLFRDYIMQGGLVSSDKESIAYILSRKGGGNLVAITVGGIREALKTRPGANKLVLRNRKGFIRLALMHGAVLVPIFSFGDNELYAKTSPGFWWKWFRDQLYKKTRLAIPFFYGRGVFQYSFGFMPYRRPITTVVGKPIEVPKIPHPSQEEVDRLHQHYLKELSNLFETHKLKYNIPKDQHLEFC", "length": 363, "header": "tr|F6R253-1|F6R253_BOVIN Isoform 1 of Acyltransferase OS=Bos taurus OX=9913 GN=LOC614494 PE=3 SV=1 CANONICAL=F6R253-1" }, "isoforms": [ { "isoform_ac": "F6R253-1", "url": "https://www.uniprot.org/uniprotkb/F6R253/entry", "sequence": { "sequence": "MLRQSLAAANTSKCLSPQQSSEKPPEPRGASMVEFAPLFVPLERRLQTFAVLYWIFCFIVLPPLCLVVFIGLLFTRFWLFNILYVIWLYLDQNRPRQGGSHNKFLKRWVLWKYMKDYFPITLVKTTELDPSRNYLAAFHPHGLLSVGAFTNMCTDSTGFSSLFPGIRPHLTTINIYFRIPLFRDYIMQGGLVSSDKESIAYILSRKGGGNLVAITVGGIREALKTRPGANKLVLRNRKGFIRLALMHGAVLVPIFSFGDNELYAKTSPGFWWKWFRDQLYKKTRLAIPFFYGRGVFQYSFGFMPYRRPITTVVGKPIEVPKIPHPSQEEVDRLHQHYLKELSNLFETHKLKYNIPKDQHLEFC", "length": 363, "header": "tr|F6R253-1|F6R253_BOVIN Isoform 1 of Acyltransferase OS=Bos taurus OX=9913 GN=LOC614494 PE=3 SV=1 CANONICAL=F6R253-1" }, "locus": { "chromosome": "15", "start_pos": 55123872, "end_pos": 55112739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056066.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056066.3" }, { "database": "Ensembl Peptide", 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"categories": [ "Protein Classification" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12283:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12283:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "23652", "url": "https://www.rhea-db.org/rhea/23652", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6R6B5", "url": "https://www.uniprot.org/uniprotkb/F6R6B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R6B5-1", "url": "https://www.uniprot.org/uniprotkb/F6R6B5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLSFPSSKEVAVSPRGFGSSCLLGQPSPRVAKVGVVGGELRLWPAQSGGEATRRRWGGGRSRPKGGEGGRRRTRVPGLVTAGGSRNRHPDSPGEMAGCRDPRVVDTLHLLLLVAVLPLAVSGVRRGAVDWTQEKNYHQPALLNVSSLRQVAEGTSISEMWQNDLRPLLIERYPGSPGSFAARQHIMQRIQRLQADWVLEVDTFLSQTPYGYRSFSNIISTLNPTAKRHLVLACHYDSKYFPHWDDRVFVGATDSAVPCAMMLELARALDKQLFSLKNISDSRPDLSLQLIFFDGEEAFHLWSPQDSLYGSRHLASKMASTPHPPGARDTNQLHGMDLLVLLDLIGAPFPTFPNFFPNTARWFGRLEAIEHGLHELGLLKDHSSERWYFRNYGYGGVIQDDHIPFLRRGVPVLHLISSPFPEVWHTMDDNEENLDRTTIDNLNKILQVFVLEYLHL", "length": 457, "header": "tr|F6R6B5-1|F6R6B5_BOVIN Isoform 1 of Glutaminyl-peptide cyclotransferase OS=Bos taurus OX=9913 GN=QPCT PE=3 SV=1 CANONICAL=F6R6B5-1" }, "isoforms": [ { "isoform_ac": "F6R6B5-1", "url": "https://www.uniprot.org/uniprotkb/F6R6B5/entry", "sequence": { "sequence": "MSLLSFPSSKEVAVSPRGFGSSCLLGQPSPRVAKVGVVGGELRLWPAQSGGEATRRRWGGGRSRPKGGEGGRRRTRVPGLVTAGGSRNRHPDSPGEMAGCRDPRVVDTLHLLLLVAVLPLAVSGVRRGAVDWTQEKNYHQPALLNVSSLRQVAEGTSISEMWQNDLRPLLIERYPGSPGSFAARQHIMQRIQRLQADWVLEVDTFLSQTPYGYRSFSNIISTLNPTAKRHLVLACHYDSKYFPHWDDRVFVGATDSAVPCAMMLELARALDKQLFSLKNISDSRPDLSLQLIFFDGEEAFHLWSPQDSLYGSRHLASKMASTPHPPGARDTNQLHGMDLLVLLDLIGAPFPTFPNFFPNTARWFGRLEAIEHGLHELGLLKDHSSERWYFRNYGYGGVIQDDHIPFLRRGVPVLHLISSPFPEVWHTMDDNEENLDRTTIDNLNKILQVFVLEYLHL", "length": 457, "header": "tr|F6R6B5-1|F6R6B5_BOVIN Isoform 1 of Glutaminyl-peptide cyclotransferase OS=Bos taurus OX=9913 GN=QPCT PE=3 SV=1 CANONICAL=F6R6B5-1" }, "locus": { "chromosome": "11", "start_pos": 19821559, "end_pos": 19791986, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018493.4", "url": "https://www.ensembl.org/id/ENSBTAT00000018493.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018493.3", "url": "https://www.ensembl.org/id/ENSBTAP00000018493.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6R6B5", "url": "https://www.uniprot.org/uniprotkb/F6R6B5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6R6B5", "url": "https://www.uniprot.org/uniprotkb/F6R6B5" } ], "pmid": "" }, { "name": "glutaminyl-peptide cyclotransferase activity", "id": "GO:0016603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016603", "evidence": [ { "database": "UniProtKB", "id": "F6R6B5", "url": "https://www.uniprot.org/uniprotkb/F6R6B5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23652", "name": "", "equation": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6R6B5-1", "A0AAF6ZAY0-1", "Q0V8G3-1", "Q28120-1" ], "evidence": [ { "id": "23652", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23652" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAF6ZAY0", "gene_name": "QPCTL", "activity": [ { "ec_number": "2.3.2.5", "activity": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 218, "end_pos": 448, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.5", "ec_name": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "2.3.2.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.2.5" }, { "id": "2.3.2.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.5" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R785-1", "uniprot_ac": "F6R785", "uniprot_id": "F6R785_BOVIN", "mass": { "chemical_mass": 49890.0, "monoisotopic_mass": 49890.0 }, "refseq": { "ac": "NP_001421815", "name": "palmitoyltransferase ZDHHC1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421815" }, "gene_names": [ { "name": "ZDHHC1", "type": "recommended", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] }, { "name": "ZDHHC1", "type": "synonym", "evidence": [ { "id": "NP_001421815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421815" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001421815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421815" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZDHHC1", "url": "https://www.uniprot.org/uniprotkb/F6R785", "locus": { "chromosome": "18", "start_pos": 35006148, "end_pos": 35027063, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038134", "url": "https://www.ensembl.org/id/ENSBTAG00000038134" } ] } } ], "crossref": [ { "id": "F6R785", "url": "https://alphafold.ebi.ac.uk/entry/F6R785", "database": "AlphaFoldDB", "categories": [] }, { "id": "517066", "url": "https://www.ncbi.nlm.nih.gov/gene/517066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FCFHIYL", "url": "https://omabrowser.org/oma/group/FCFHIYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22883:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001421815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R785-1", "url": "https://www.uniprot.org/uniprotkb/F6R785-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYKMNICNKPSNKTAPEKNVWTAPAQASGPSPELQGQRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYAGPLPIFNRSQHAHVIEDLHCNLCDVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNRHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPPQEAKGAHRELESCPPKMRPIQSLPIPCYPRPSGASTALLPRDSRSAPRIQPQKKRKRRMYKVPTSGTLNREPQLPRLPGPRTPGRRSSSSSDSADASPAEAYHSASGESLDEIPVAQTRLGSAALAAPVGRPREPGLALQARAPAVFVSPSSGEPRARGGPEADLA", "length": 454, "header": "tr|F6R785-1|F6R785_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC1 PE=3 SV=1 CANONICAL=F6R785-1" }, "isoforms": [ { "isoform_ac": "F6R785-1", "url": "https://www.uniprot.org/uniprotkb/F6R785/entry", "sequence": { "sequence": "MYKMNICNKPSNKTAPEKNVWTAPAQASGPSPELQGQRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYAGPLPIFNRSQHAHVIEDLHCNLCDVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNRHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPPQEAKGAHRELESCPPKMRPIQSLPIPCYPRPSGASTALLPRDSRSAPRIQPQKKRKRRMYKVPTSGTLNREPQLPRLPGPRTPGRRSSSSSDSADASPAEAYHSASGESLDEIPVAQTRLGSAALAAPVGRPREPGLALQARAPAVFVSPSSGEPRARGGPEADLA", "length": 454, "header": "tr|F6R785-1|F6R785_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC1 PE=3 SV=1 CANONICAL=F6R785-1" }, "locus": { "chromosome": "18", "start_pos": 35019398, "end_pos": 35006516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045963.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045963.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043304.3", "url": "https://www.ensembl.org/id/ENSBTAP00000043304.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JWN6-1", "protein_name": "Palmitoyltransferase", "gene_name": "Zdhhc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNICNKPSNKTAPEKSVWTAPSQDSGPSPELQGQRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHPWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYSGPLPIFNRSQHAHVIEDLHCNLCDVDVQSCGGGTPLIPALRSQEADRSLSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNQHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHMYLMWHKLTTYEYIVQHRPAQEAKETHKELESCPRKMRPIKEMEFYMRTFSHVRPEPSGQARPAALNVHPSQFLATQGQVEPPLPSSSDTLALPPRIQPQKKRKRRVYKLSRSGVLGREPPLPRIQGTGTPGRHSSSSSDSISASPVHVAGSAGAYYSASAESMEEIPVAQTRLGSAALGAPGTRGRESGLALQARSPAVFVSPSSGEPGTPGGGEDGLP", "length": 507 }, "evidence": [ { "id": "F6R785", "url": "https://omabrowser.org/oma/group/F6R785/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7F4Z4-1", "protein_name": "Palmitoyltransferase ZDHHC1", "gene_name": "zdhhc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVCSKNSNRTAPVSEGGIRRADVPLCSRTNGWSWPPHPFQFLAWLLYLYFAVTGFGVFVPLLPTHWIPAGYICTGITFVCHLFMHLMAVSIDPADYNVRAKSYKGPMPVFDRTKHAHVIENCHCYLCEVDVGPKSKHCSACNKCVASFDHHCRWLNNCVGSRNYWLFLNSVISALLGIVLVVVIASYVFIEFFLDPSKLRSDKHFQQVRNESVVWFVFLPVAPVTTAGPAIPALAGVTIALGLLSALLLGHLLCFHIYLMWNRLSTYEYIVRQRHRQEAGDSRKPPPENDSGVPKLNLIKQQVSYSGTLGYTNPEMEVEDPKAMTSQEGAARYGNGRIRCSSEHMDEEEHLPSVLTEQKASPHPHKHAQKKKRKVRKLAAEVNGDISIDTSTAKGLQKTSAEKESSVAAATVSSSLGQRLPFPAFPLRASLPPLAPVQAAGPPAEYHSDSAESLEEIPVAMARLGSAALAGAQIPTTTATASSSYSSMLQCALPSSAAGHAAPSPQPRTKRKTAARTVSEQRFEMLYHNPSMFMTRESGEPAIPPEESPRAAKRKQTGKKRNTEDAKPSSRVGTSLA", "length": 578 }, "evidence": [ { "id": "F6R785", "url": "https://omabrowser.org/oma/group/F6R785/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7F2Z1-1", "protein_name": "Palmitoyltransferase", "gene_name": "Zdhhc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNICNKPSNKTAPEKNVWTAPSQDSGPSPELQGQRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYSGPLPIFNRSQHAHVIEDLHCNLCDVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNQHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPAQEAKETHKELESCPRKMRSIQEMEFYMRTFSHVRPEPSGQARPAALNAKKGTSSRRDSGAASRVCSLAFTSVLPSFLPHKAKWNHHCPPPQTHWLCLHGSNPRKRGSGEYIDCPGLGPWTESSGCPSYVTLGLLAATLALPLIPPVPAQHMLVAL", "length": 440 }, "evidence": [ { "id": "F6R785", "url": "https://omabrowser.org/oma/group/F6R785/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R0N9-1", "protein_name": "Palmitoyltransferase ZDHHC1", "gene_name": "Zdhhc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNICNKPSNKTAPEKSVWTAPSQDSGPSPELQGQRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYSGPLPIFNRSQHAHVIEDLHCNLCDVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNQHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPAQEAKETHKELESCPRKVRSIQEMEFYMRTFSHVRPEPSGQARTAALNANPSQFLATQGQVEPPLPSSSDTLALPPRIQPQKKRKRRVYRLPRSGVLDRELPLPRLRETGTPSRRSSSSSDSTSASPVHAGGSAGAYYSASAESMEEIPVAQTRLGSAALGAPGARGRESGLALQARSPAVFVSPSSGEPGTPGGGDGLP", "length": 484 }, "evidence": [ { "id": "F6R785", "url": "https://omabrowser.org/oma/group/F6R785/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WTX9-1", "protein_name": "Palmitoyltransferase ZDHHC1", "gene_name": "ZDHHC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYKMNICNKPSNKTAPEKSVWTAPAQPSGPSPELQGQRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGILVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYAGPLPIFNRSQHAHVIEDLHCNLCNVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNRHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPPQEAKGVHRELESCPPKMRPIQEMEFYMRTFRHMRPEPPGQAGPAAVNAKHSRPASPDPTPGRRDCAGPPVQVEWDRKKPLPWRSPLLLLAMWGPQAPPCLCRKRGRGACIKCERLRPRIRRRGLGPPAAAPARRRIPRTPALCTPLALPAPTTRRRQSPWTRFQWRRRAWAAPLWPPRGAGADSPRWRGRRVRPPFS", "length": 485 }, "evidence": [ { "id": "F6R785", "url": "https://omabrowser.org/oma/group/F6R785/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of protein localization to endosome", "id": "GO:1905668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905668", "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "pmid": "" }, { "name": "positive regulation of protein oligomerization", "id": "GO:0032461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032461", "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "pmid": "" }, { "name": "positive regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900227", "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "F6R785", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X756-1", "E1BPA5-1", "F1MVC6-1", "E1B987-1", "E1BJK1-1", "F6R785-1", "A0AAA9TDW4-1", "A0AAA9TVJ9-1", "A0AAA9TM40-1", "E1B6X9-1", "E1BKA0-1", "E1BK60-1", "Q58CU4-1", "A2VDT6-1", "A0AAF6ZH94-1", "A0AAA9RZ07-1", "Q0VC89-1", "E1BLT8-1", "G3MXF3-1", "P15103-1", "Q2HJ95-1", "Q58DA8-1", "A0A3Q1M794-1", "A0A3Q1LVW6-1", "Q58DT3-1", "A0A3Q1M403-1", "A0ABI0NXA5-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LVW6", "gene_name": "ZDHHC13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] } ] }, { "uniprot_ac": "A0A3Q1M403", "gene_name": "", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] } ] }, { "uniprot_ac": "A0A3Q1M794", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] } ] }, { "uniprot_ac": "A0AAA9RZ07", "gene_name": "ZDHHC8", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] } ] }, { "uniprot_ac": "A0AAA9TDW4", "gene_name": "ZDHHC7", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] } ] }, { "uniprot_ac": "A0AAA9TM40", "gene_name": "ZDHHC18", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] } ] }, { "uniprot_ac": "A0AAA9TVJ9", "gene_name": "ZDHHC23", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] } ] }, { "uniprot_ac": "A0AAF6ZH94", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] } ] }, { "uniprot_ac": "A0ABI0NXA5", "gene_name": "ZDHHC15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] } ] }, { "uniprot_ac": "A2VDT6", "gene_name": "ZDHHC21", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] } ] }, { "uniprot_ac": "E1B6X9", "gene_name": "ZDHHC12", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] } ] }, { "uniprot_ac": "E1B987", "gene_name": "ZDHHC22", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] } ] }, { "uniprot_ac": "E1BJK1", "gene_name": "ZDHHC17", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] } ] }, { "uniprot_ac": "E1BK60", "gene_name": "ZDHHC14", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] } ] }, { "uniprot_ac": "E1BKA0", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] } ] }, { "uniprot_ac": "E1BLT8", "gene_name": "ZDHHC5", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] } ] }, { "uniprot_ac": "E1BPA5", "gene_name": "ZDHHC24", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] } ] }, { "uniprot_ac": "F1MVC6", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] } ] }, { "uniprot_ac": "F6R785", "gene_name": "ZDHHC1", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] } ] }, { "uniprot_ac": "G3MXF3", "gene_name": "ZDHHC2", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] } ] }, { "uniprot_ac": "G3X756", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] } ] }, { "uniprot_ac": "P15103", "gene_name": "GLUL", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] } ] }, { "uniprot_ac": "Q0VC89", "gene_name": "ZDHHC20", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] } ] }, { "uniprot_ac": "Q2HJ95", "gene_name": "ZDHHC6", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ95" } ] } ] }, { "uniprot_ac": "Q58CU4", "gene_name": "ZDHHC16", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58CU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CU4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58CU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CU4" } ] } ] }, { "uniprot_ac": "Q58DA8", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58DA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DA8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58DA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DA8" } ] } ] }, { "uniprot_ac": "Q58DT3", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q58DT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DT3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q58DT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DT3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" }, { "id": "PF01529", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Palmitoyltransferase DHHC", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 284, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.225", "ec_name": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "2.3.1.225", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.225" }, { "id": "2.3.1.225", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.225" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 12, "end_pos": 14 }, { "start_pos": 222, "end_pos": 224 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R7G2-1", "uniprot_ac": "F6R7G2", "uniprot_id": "F6R7G2_BOVIN", "mass": { "chemical_mass": 76891.0, "monoisotopic_mass": 76891.0 }, "refseq": {}, "gene_names": [ { "name": "SLC13A4", "type": "recommended", "evidence": [ { "id": "F6R7G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R7G2" } ] } ], "protein_names": [ { "name": "Solute carrier family 13 member 4", "type": "synonym", "evidence": [ { "id": "F6R7G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R7G2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R7G2", "url": "https://www.uniprot.org/uniprotkb/F6R7G2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC13A4", "url": "https://www.uniprot.org/uniprotkb/F6R7G2", "locus": { "chromosome": "4", "start_pos": 99483658, "end_pos": 99525812, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003864", "url": "https://www.ensembl.org/id/ENSBTAG00000003864" } ] } } ], "crossref": [ { "id": "F6R7G2", "url": "https://alphafold.ebi.ac.uk/entry/F6R7G2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003864", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003864", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TFVRQTN", "url": "https://omabrowser.org/oma/group/TFVRQTN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6R7G2", "url": "https://www.orthodb.org/?gene=F6R7G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-433137", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-433137", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6R7G2", "url": "https://www.uniprot.org/uniprotkb/F6R7G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R7G2-1", "url": "https://www.uniprot.org/uniprotkb/F6R7G2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLCSPIPPKTGGEEPGFWCRQGLYLPSCSAHKTKEDSWKPRKVGEVFLDGGERRQAAQHLAGAGSEGRRSRMGLLKGLLGARKLLLVILVPLLLLPLPMLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSSEVAGEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEEEQLVAGNSSAEEAEPINLDVNNSQPPLELIFVNEDTSNADFNSLMQNKNRNGVPTVTNSAETANLPGRKQHPSQEKPPVLTPSSRNQELKRKYKSQHDQMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREELSEKRIQEEYEKLGAITYPEMVTGFFFVLMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKRDGEDRGPSLGMESIITWKDFQKTMPWEIVILVGGGYALASGSKTSGLSTWIGQQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPIVCSLSETLQINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVTVMVAINTWGISLFDLNTFPAWAKVSNITDQA", "length": 698, "header": "tr|F6R7G2-1|F6R7G2_BOVIN Isoform 1 of Solute carrier family 13 member 4 OS=Bos taurus OX=9913 GN=SLC13A4 PE=3 SV=1 CANONICAL=F6R7G2-1" }, "isoforms": [ { "isoform_ac": "F6R7G2-1", "url": "https://www.uniprot.org/uniprotkb/F6R7G2/entry", "sequence": { "sequence": "MRLCSPIPPKTGGEEPGFWCRQGLYLPSCSAHKTKEDSWKPRKVGEVFLDGGERRQAAQHLAGAGSEGRRSRMGLLKGLLGARKLLLVILVPLLLLPLPMLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSSEVAGEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEEEQLVAGNSSAEEAEPINLDVNNSQPPLELIFVNEDTSNADFNSLMQNKNRNGVPTVTNSAETANLPGRKQHPSQEKPPVLTPSSRNQELKRKYKSQHDQMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREELSEKRIQEEYEKLGAITYPEMVTGFFFVLMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKRDGEDRGPSLGMESIITWKDFQKTMPWEIVILVGGGYALASGSKTSGLSTWIGQQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPIVCSLSETLQINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVTVMVAINTWGISLFDLNTFPAWAKVSNITDQA", "length": 698, "header": "tr|F6R7G2-1|F6R7G2_BOVIN Isoform 1 of Solute carrier family 13 member 4 OS=Bos taurus OX=9913 GN=SLC13A4 PE=3 SV=1 CANONICAL=F6R7G2-1" }, "locus": { "chromosome": "4", "start_pos": 99525613, "end_pos": 99484719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005040.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005040.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005040.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005040.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-433137", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-433137", "resource": "Reactome", "description": "Sodium-coupled sulphate, di- and tri-carboxylate transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YBN9-1", "protein_name": "Solute carrier family 13 member 4", "gene_name": "SLC13A4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAMVKEILRSRNLLLVVLIPLLLLPLPLLYPCSEASCAYVLIVTAVYWVSEAVPLGAAALIPAFLYPLFGVMKSSEVAAEYFKNTTLLLMGVICVAASVEKWNLHKRIALRMVMMAGAKPGMLLLCFMCCTTVLSMWLSNTSTTAMVMPIVEAVLQELVNAEEEHDVISTTGNTIIEENESIGLNEKHDQPSLELIFINEDATTTDFSSLMHSKTMNSVHMIANPIGTMKSRSNGQHLPQAQILVLPPKPSELDLSTKYQYQSRHDHMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPNAEVVNFGTWFLFSFPISLIMLALTWLWMHWLFLGCNFKETCSVSKKKKTKREEMSERRIHEEYKKLGNVSYPEMVTGFFFILMTLLWFTREPGFVPGWSSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKGKGDAERSTDANTLDPIITWKDFQKTMPWEIVVLVGGGYALAAGCKTSGLSTWIGRQMLSLSSLPYWAVTLLACILVSLVTEFVSNPATITIFLPILCSMSETLLINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNLIGLAVVMVAINTWGIRLFQLNTFPEWAAVSNVTIQT", "length": 633 }, "evidence": [ { "id": "F6R7G2", "url": "https://omabrowser.org/oma/group/F6R7G2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SNI6-1", "protein_name": "Solute carrier family 13 member 4", "gene_name": "SLC13A4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLLKGLLRARKLLLIILVPLLLLPLPVLHPSSEAACAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTMLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTMLSMWLSNTSTTAMVMPIVEAVLQELVSAEEEQLVAGNASAEEAELISLKANNSQPSLELIFVNEDTSNADFSSLMMNKNLNGVPTVTSPVKTANHQDQKRHPPQEKPPVPTPRPRNQELKKKYKSQHDQMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPGADVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREELSEKRIQQEYEKLGAVSYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYCTDATVSIFLGFLLFLIPAKKPCFRKKNDGEDQEPSPGMEPIITWKDFQKTMPWEIVILVGGGYALASGSKTSGLSTWIGYQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGINVIGLVIVMVAINTWGINLFHLDTYPAWAKVGNVTDQA", "length": 626 }, "evidence": [ { "id": "F6R7G2", "url": "https://omabrowser.org/oma/group/F6R7G2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9UKG4-1", "protein_name": "Solute carrier family 13 member 4", "gene_name": "SLC13A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGVSLFHLDTYPAWARVSNITDQA", "length": 626 }, "evidence": [ { "id": "F6R7G2", "url": "https://omabrowser.org/oma/group/F6R7G2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "solute:sodium symporter activity", "id": "GO:0015370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015370", "evidence": [ { "database": "UniProtKB", "id": "F6R7G2", "url": "https://www.uniprot.org/uniprotkb/F6R7G2" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "F6R7G2", "url": "https://www.uniprot.org/uniprotkb/F6R7G2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6R7G2", "url": "https://www.uniprot.org/uniprotkb/F6R7G2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F6R7G2", "url": "https://www.uniprot.org/uniprotkb/F6R7G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R7G2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 698, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R7G2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R7G2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 693, "end_pos": 695 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R921-1", "uniprot_ac": "F6R921", "uniprot_id": "F6R921_BOVIN", "mass": { "chemical_mass": 32473.0, "monoisotopic_mass": 32473.0 }, "refseq": { "ac": "XP_005205887", "name": "GTPase, IMAP family member 1-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205887" }, "gene_names": [ { "name": "LOC512867", "type": "recommended", "evidence": [ { "id": "F6R921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R921" } ] }, { "name": "LOC512867", "type": "synonym", "evidence": [ { "id": "XP_005205887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205887" } ] } ], "protein_names": [ { "name": "AIG1-type G domain-containing protein", "type": "recommended", "evidence": [ { "id": "F6R921", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R921/entry#names_and_taxonomy" } ] }, { "name": "GTPase, IMAP family member 1-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005205887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205887" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R921", "url": "https://www.uniprot.org/uniprotkb/F6R921" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC512867", "url": "https://www.uniprot.org/uniprotkb/F6R921", "locus": {} } ], "crossref": [ { "id": "F6R921", "url": "https://alphafold.ebi.ac.uk/entry/F6R921", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040331", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040331", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512867", "url": "https://www.ncbi.nlm.nih.gov/gene/512867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CGGQVCA", "url": "https://omabrowser.org/oma/group/CGGQVCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6R921", "url": "https://www.orthodb.org/?gene=F6R921", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04548", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005205887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6R921", "url": "https://www.uniprot.org/uniprotkb/F6R921", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R921-1", "url": "https://www.uniprot.org/uniprotkb/F6R921-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGRKVARDEENAYGFQEFRSALQERRLRLLLAGRSGTGKSATGNSILQRKHFLSRLATTAVTRACATGSCCWASWDVEVLDTPDLFSPEVAQADPGFKERGRCYLLSAPGPHAVLLVTQLGRFTAQDLQAWRGVKALFGAGIAARAVVVFTRREDLDGGSLQQYVRDTDNRALRELVAECGGRCCAFDNRAADGEREAQVRELMGLVEELVRDHGGAPYTNDVYHLAQTLGGLSPEERLRRVAERLAARAPSWSERWPLAGLWRWPKAAPETWCKLGLVALLGALFLLYLLCR", "length": 294, "header": "tr|F6R921-1|F6R921_BOVIN Isoform 1 of AIG1-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC512867 PE=3 SV=1 CANONICAL=F6R921-1" }, "isoforms": [ { "isoform_ac": "F6R921-1", "url": "https://www.uniprot.org/uniprotkb/F6R921/entry", "sequence": { "sequence": "MGGRKVARDEENAYGFQEFRSALQERRLRLLLAGRSGTGKSATGNSILQRKHFLSRLATTAVTRACATGSCCWASWDVEVLDTPDLFSPEVAQADPGFKERGRCYLLSAPGPHAVLLVTQLGRFTAQDLQAWRGVKALFGAGIAARAVVVFTRREDLDGGSLQQYVRDTDNRALRELVAECGGRCCAFDNRAADGEREAQVRELMGLVEELVRDHGGAPYTNDVYHLAQTLGGLSPEERLRRVAERLAARAPSWSERWPLAGLWRWPKAAPETWCKLGLVALLGALFLLYLLCR", "length": 294, "header": "tr|F6R921-1|F6R921_BOVIN Isoform 1 of AIG1-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC512867 PE=3 SV=1 CANONICAL=F6R921-1" }, "locus": { "chromosome": "4", "start_pos": 113133656, "end_pos": 113131630, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052584.3", "url": "https://www.ensembl.org/id/ENSBTAT00000052584.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051857.2", "url": "https://www.ensembl.org/id/ENSBTAP00000051857.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 63, "start_aa": "Thr", "end_pos": 63, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr63", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZSW5-1", "protein_name": "GTPase, IMAP family member 1", "gene_name": "GIMAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "AQNSIPTHTCEEKAELRSFSDPTNQEEGALAEDRHHSHLEVAEPLCPSRHHEGSEDLQAALQEPRLRLLLAGRTGAGKSSTGNSILGRKHFDSRLRATSVTRSCAVASGRWAEWDVDVLDTPDLFSSEVARTDPDCKERGRCYLLAAPGPHALLLVTQLGRFTAQDQQAWRGVKALFGDGVSAHTIVVFTRKEDLAEGSLQDYVRDSENQALRQLVAECGGRVCAFNNRATGPEQEAQVTELLRLVEDLVRDRGGAPYTNDVYHLAQALGGVSPEERLRKVAERVAQKQQGCCLQRFLCEKPKAQRTWWALALAVLAIVILIALFFFKGP", "length": 330 }, "evidence": [ { "id": "F6R921", "url": "https://omabrowser.org/oma/group/F6R921/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9C8U7-1", "protein_name": "Immune-associated nucleotide-binding protein 4", "gene_name": "IAN4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGLEDTTDLRLPSASEPIKNIVLVGRTGNGKSATGNSLIGKQVFRSETRATGVTMKCETCVAVTPCGTGINVIDTPGLFDLSVSAEYLSQEIINCLVLAEDGLHAVVLVLSVRTRISQEEEATLNTLQVIFGSQIIDYLVVLFTGGDELEANNMTLDDYLSKGCPEFLKTVLRLCGGRRILFDNRTTDEGKKVKQVQELLAHVAAIEKSTSGIPFTDEMHRKIQKEAETLREQQKEVESKDLAAAEIEKWKKHYQTEHDKNMNMMAEMLGNRLREDSERQEKMLLALRDNLEISQRQNKLNELTDNEPDLIHCGVSLRRMPCNML", "length": 326 }, "evidence": [ { "id": "F6R921", "url": "https://omabrowser.org/oma/group/F6R921/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F6R921", "url": "https://www.uniprot.org/uniprotkb/F6R921" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F6R921", "url": "https://www.uniprot.org/uniprotkb/F6R921" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6R921", "url": "https://www.uniprot.org/uniprotkb/F6R921" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R921-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 294, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R921-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R921" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R921", "database": "UniProtKB", "url": 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taurus OX=9913 GN=CCR8 PE=3 SV=1 CANONICAL=F6RDR3-1" }, "isoforms": [ { "isoform_ac": "F6RDR3-1", "url": "https://www.uniprot.org/uniprotkb/F6RDR3/entry", "sequence": { "sequence": "MDYTPEPNLTTATDFYYPDIYSSPCDGEGRESKLLLAVFYCILFVFGLLGNSLVILVLVACKKLRSVTDVYLLNLALSDLLFVFSFPFQTHYQLDQWVFGTVMCKVVSGFYYIGFFSSMFFITLMSMDRYLAVVHAVYALKVRTISMGTALSLVVWLTALVATSPLLVFYQVASENGILQCYSYYNQQTLKWKIFIHFEVNILGLLIPFSILMFCYIRILHQLKSCQNHNKTKAIKLVLIVVVASLLFWVPFNTVLFLTSLHDMHVLDGCVMSQQLTYATHVTETISFTHCCVNPIIYAFMGEKFKKHLSELFRKSCSHTLVYIGRQVSREVLEKSSSNQQSSRSSTVDYIL", "length": 352, "header": "tr|F6RDR3-1|F6RDR3_BOVIN Isoform 1 of C-C motif chemokine receptor 8 OS=Bos taurus OX=9913 GN=CCR8 PE=3 SV=1 CANONICAL=F6RDR3-1" }, "locus": { "chromosome": "22", "start_pos": 12635669, "end_pos": 12634614, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089752.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089752.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092961.1", "url": 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"MDYTLEPNVTVTDYYPDVFTIPCDTELALRGGRLHLAVFYCILFVLGLLGNSLVILVLVACKKLRSITDIYLLNLAVSDLLFVFSVPFQTHYLLDQWVFGTAMCKVVSGFYYIGFFSSMFFITLMSVDRYLAVVHAVYAIKVRTARVGTALSLAVWLTAVAATLPLLVFYQVASDDGVLQCFPFYDNQSLRWKLSVHFEVNILGLLLPFAILLFCYVRILHQLRGCQNHNRTRAVKLVLIVVMASLLFWVPFNVVLFLTSLHDLHVLDGCATSQRLALATHVTEVISFTHCCVNPVIYAFIGEKFKKNLAGVFQKSCSHIFLYVGRQVPLGAWERQPSSNQRSSQSSTLDYIL", "length": 353 }, "evidence": [ { "id": "F6RDR3", "url": "https://omabrowser.org/oma/group/F6RDR3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P51685-1", "protein_name": "C-C chemokine receptor type 8", "gene_name": "CCR8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RFZ0-1", "uniprot_ac": "F6RFZ0", "uniprot_id": "F6RFZ0_BOVIN", "mass": { "chemical_mass": 22869.0, "monoisotopic_mass": 22869.0 }, "refseq": {}, "gene_names": [ { "name": "SFT2D1", "type": "recommended", "evidence": [ { "id": "F6RFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0" } ] } ], "protein_names": [ { "name": "Vesicle transport protein", "type": "recommended", "evidence": [ { "id": "F6RFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0#function" }, { "database": "UniProtKB", "id": "RU363111", "url": "https://www.uniprot.org/uniprotkb/RU363111#function" }, { "database": "UniProtKB", "id": "ARBA00003566", "url": "https://www.uniprot.org/uniprotkb/ARBA00003566#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SFT2D1", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0", "locus": { "chromosome": "9", "start_pos": 101304079, "end_pos": 101319465, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002993", "url": "https://www.ensembl.org/id/ENSBTAG00000002993" } ] } } ], "crossref": [ { "id": "F6RFZ0", "url": "https://alphafold.ebi.ac.uk/entry/F6RFZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002993", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002993", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IAAIVWK", "url": "https://omabrowser.org/oma/group/IAAIVWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RFZ0", "url": "https://www.orthodb.org/?gene=F6RFZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23137:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23137:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RFZ0-1", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTPLGRPPGAEPARRKLETGTSGQPEESRLPGFLRGRERGGPGGAAAAMEKLRRVLSGQDDEEQGLTAQVLDASTLSFNTRLKWFAICFVSGIFFSILGTGLLWLPGGIKLFAVFYTFGNIAALASTCFLMGPVKQLKKMFETTRLLATVIMLLCFVLTLCAALWWHKKGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS", "length": 208, "header": "tr|F6RFZ0-1|F6RFZ0_BOVIN Isoform 1 of Vesicle transport protein OS=Bos taurus OX=9913 GN=SFT2D1 PE=3 SV=1 CANONICAL=F6RFZ0-1" }, "isoforms": [ { "isoform_ac": "F6RFZ0-1", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0/entry", "sequence": { "sequence": "MRTPLGRPPGAEPARRKLETGTSGQPEESRLPGFLRGRERGGPGGAAAAMEKLRRVLSGQDDEEQGLTAQVLDASTLSFNTRLKWFAICFVSGIFFSILGTGLLWLPGGIKLFAVFYTFGNIAALASTCFLMGPVKQLKKMFETTRLLATVIMLLCFVLTLCAALWWHKKGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS", "length": 208, "header": "tr|F6RFZ0-1|F6RFZ0_BOVIN Isoform 1 of Vesicle transport protein OS=Bos taurus OX=9913 GN=SFT2D1 PE=3 SV=1 CANONICAL=F6RFZ0-1" }, "locus": { "chromosome": "9", "start_pos": 101319266, "end_pos": 101304576, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003895.4", "url": "https://www.ensembl.org/id/ENSBTAT00000003895.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003895.3", "url": "https://www.ensembl.org/id/ENSBTAP00000003895.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N427-1", "protein_name": "Vesicle transport protein", "gene_name": "Sft2d1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFIICFVAGVFCSILGTGLLWLPNGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFETTRLLATVIMLLCFVFTLCAALWWRKKGLALLFCILQFLSMTWYSLSYIPYARDAVLKCCSSLFS", "length": 159 }, "evidence": [ { "id": "F6RFZ0", "url": "https://omabrowser.org/oma/group/F6RFZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XTJ6-1", "protein_name": "Vesicle transport protein", "gene_name": "SFT2D1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "LSSSGAEITLGKWEAKLPLSAIHCLVLDASTLSFGTRVKWFAICFIAGVACSILGTALLWLPKGIKLFAVFYTLGNIAALASTCFLMGPLKQLKTMFEPKRLIATVVMLLFLVLTLCAVFWWNKKGLALIFCILQFLAMTWYSLSYIPYARDAVIKCFTSCLE", "length": 163 }, "evidence": [ { "id": "F6RFZ0", "url": "https://omabrowser.org/oma/group/F6RFZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SBY3-1", "protein_name": "Vesicle transport protein", "gene_name": "SFT2D1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASTLSFNTRLKWFVICFVSGIFFSFLGTGLLWLPGGIKLFAVFYTFGNIAALASTCFLMGPVKQLKKMFETTRLLATIVMILCLVLTLCAALWWRKKGLALLFCILQFLSLTWYSLSYIPYARDAVIKCCSSLLS", "length": 159 }, "evidence": [ { "id": "F6RFZ0", "url": "https://omabrowser.org/oma/group/F6RFZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5SSN7-1", "protein_name": "Vesicle transport protein SFT2A", "gene_name": "Sft2d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFVICFVAGIFFSFLGTGLLWLPNGMKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFETTRLLATIIMLLCLVFTLCAALWWRKKGLALLFCILQFLSMTWYSLSYIPYARDAVLKCCSSLLG", "length": 159 }, "evidence": [ { "id": "F6RFZ0", "url": "https://omabrowser.org/oma/group/F6RFZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WV19-1", "protein_name": "Vesicle transport protein SFT2A", "gene_name": "SFT2D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPGGIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWHKKGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS", "length": 159 }, "evidence": [ { "id": "F6RFZ0", "url": "https://omabrowser.org/oma/group/F6RFZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LT07-1", "protein_name": "Vesicle transport protein", "gene_name": "MQM1.18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKMNQAIEKMKMLVGMEVEDEQQAADEESSLSFMEDLNRNCALTTKQRFYGFAICLSAGLTCTLLSMLVFFNPVKFGITFTLGNLMALGSTAFLIGPQRQVTMMLDPARIYATALYLASIIIALFCALYVRNKLLTLLAIILEFTGLIWYSLSYIPFARTMVSKIFMTCFDTEF", "length": 175 }, "evidence": [ { "id": "F6RFZ0", "url": "https://omabrowser.org/oma/group/F6RFZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VPD4-1", "protein_name": "Vesicle transport protein", "gene_name": "Dmel\\CG5104", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKLRRVLSGDEPTPEEESSIITQINDMSTLSWSTRIKGFVICFALGILLSLLGSVALFLHRGIVVFAVFYTLGNVISMASTCFLMGPFKQIKKMFAETRLIATIIVLVMMVLTFIAAIVWKKAGLTLIFIIIQSLAMTWYSLSYIPYARDAVKKTMSAILEV", "length": 163 }, "evidence": [ { "id": "F6RFZ0", "url": "https://omabrowser.org/oma/group/F6RFZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F6RFZ0", "url": "https://www.uniprot.org/uniprotkb/F6RFZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RFZ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 208, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RFZ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RFZ0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RG16-1", "uniprot_ac": "F6RG16", "uniprot_id": "F6RG16_BOVIN", "mass": { "chemical_mass": 67479.0, "monoisotopic_mass": 67479.0 }, "refseq": {}, "gene_names": [ { "name": "ENO4", "type": "recommended", "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ] } ], "protein_names": [ { "name": "Enolase 4", "type": "recommended", "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16/entry#names_and_taxonomy" } ] }, { "name": "2-phospho-D-glycerate hydro-lyase", "type": "synonym", "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.11", "type": "synonym", "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RG16", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ENO4", "url": "https://www.uniprot.org/uniprotkb/F6RG16", "locus": { "chromosome": "26", "start_pos": 37268612, "end_pos": 37240224, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004330", "url": "https://www.ensembl.org/id/ENSBTAG00000004330" } ] } } ], "crossref": [ { "id": "F6RG16", "url": "https://alphafold.ebi.ac.uk/entry/F6RG16", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004330", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004330", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22974", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22974", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "767880", "url": "https://www.ncbi.nlm.nih.gov/gene/767880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MKELICI", "url": "https://omabrowser.org/oma/group/MKELICI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11902:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11902:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00113", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00113", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-70171", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70171", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-70263", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70263", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10164", "url": "https://www.rhea-db.org/rhea/10164", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M3E4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3E4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RG16", "url": "https://www.uniprot.org/uniprotkb/F6RG16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RG16-1", "url": "https://www.uniprot.org/uniprotkb/F6RG16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEEGGGRSCGSTRELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTICKVVGKNVLDGLGLPTLQVEIFCTIQNFPKNICSVVIATHFEAHENASPELVEAEEVERLDAVSTAVQWVNETLTEELQGLVPSSQAEVDQVLRTFFENKVQEDKERKELEKNLEDSTVLSPQPPPPPPPPPPPSKKKGQKQGRMETSAEKPIIPAEPPEPVLCGSMAIGAVSLAVAKASAVLDNNPLYLNIALLKHHQEQPKKLTIPLLMVSLVSCGKSSPGKLNLMKEVICIPHPGLTAKQGVEMLLEIQKHINKAIEMSPPPKPETKKSHDGGKRGQQQITGKMSHLGCLTINYDTIEQPLLLIQGICANLGLELGTNLHLAINCAAHELMDYSKGKYEVMMGTYKNAAEMVDLYVDLINKFPSIIALIDPFRKEDSEQWDSIYNALGSRCYIIAGTASKSISKLLEEGNISILKYSGLIIKHINQTTMSDLVEITNLIDGKKLIAVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLFTIEEELGQNGTLGFNEEHTFFSWNEEAEEAGELHEVPEPIFPTEVAEDLAKL", "length": 613, "header": "tr|F6RG16-1|F6RG16_BOVIN Isoform 1 of Enolase 4 OS=Bos taurus OX=9913 GN=ENO4 PE=3 SV=2 CANONICAL=F6RG16-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M3E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3E4/entry", "sequence": { "sequence": "MTVLHSCFSSSSLAGDTSTLGPVLKANCFSKLAKPPTICKVVGKNVLDGLGLPTLQVEIFCTIQNFPKNICSVVIATHFEAHENASPELVEAEEVERLDAVSTAVQWVNETLTEELQGLVPSSQAEVDQVLRTFFENKVQEDKERKELEKNLEDSTVLSPQPPPPPPPPPPPSKKKGQKQGRMETSAEKPIIPAEPPEPVLCGSMAIGAVSLAVAKASAVLDNNPLYLNIALLKHHQEQPKKLTIPLLMVSLVSCGKSSPGKLNLMKEVICIPHPGLTAKQGVEMLLEIQKHINKAIEMSPPPKPETKKSHDGGKRGQQQITGKMSHLGCLTINYDTIEQPLLLIQGICANLGLELGTNLHLAINCAAHELMDYSKGKYEVMMGTYKNAAEMVDLYVDLINKFPSIIALIDPFRKEDSEQWDSIYNALGSRCYIIAGTASKSISKLLEEGNISILKYSGLIIKHINQTTMSDLVEITNLIDGKKLIAVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLFTIEEELGQNGTLGFNEEHTFFSWNEEAEEAGELHEVPEPIFPTEVAEDLAKL", "length": 583, "header": "tr|A0A3Q1M3E4-1|A0A3Q1M3E4_BOVIN Computationally mapped isoform of phosphopyruvate hydratase OS=Bos taurus OX=9913 GN=ENO4 PE=3 SV=1 CANONICAL=F6RG16-1" }, "locus": { "chromosome": "26", "start_pos": 37267873, "end_pos": 37240310, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078378.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078378.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064639.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064639.1" } ] } }, { "isoform_ac": "F6RG16-1", "url": "https://www.uniprot.org/uniprotkb/F6RG16/entry", "sequence": { "sequence": "MGEEGGGRSCGSTRELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTICKVVGKNVLDGLGLPTLQVEIFCTIQNFPKNICSVVIATHFEAHENASPELVEAEEVERLDAVSTAVQWVNETLTEELQGLVPSSQAEVDQVLRTFFENKVQEDKERKELEKNLEDSTVLSPQPPPPPPPPPPPSKKKGQKQGRMETSAEKPIIPAEPPEPVLCGSMAIGAVSLAVAKASAVLDNNPLYLNIALLKHHQEQPKKLTIPLLMVSLVSCGKSSPGKLNLMKEVICIPHPGLTAKQGVEMLLEIQKHINKAIEMSPPPKPETKKSHDGGKRGQQQITGKMSHLGCLTINYDTIEQPLLLIQGICANLGLELGTNLHLAINCAAHELMDYSKGKYEVMMGTYKNAAEMVDLYVDLINKFPSIIALIDPFRKEDSEQWDSIYNALGSRCYIIAGTASKSISKLLEEGNISILKYSGLIIKHINQTTMSDLVEITNLIDGKKLIAVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLFTIEEELGQNGTLGFNEEHTFFSWNEEAEEAGELHEVPEPIFPTEVAEDLAKL", "length": 613, "header": "tr|F6RG16-1|F6RG16_BOVIN Isoform 1 of Enolase 4 OS=Bos taurus OX=9913 GN=ENO4 PE=3 SV=2 CANONICAL=F6RG16-1" }, "locus": { "chromosome": "26", "start_pos": 37267873, "end_pos": 37241122, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045697.4", "url": "https://www.ensembl.org/id/ENSBTAT00000045697.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043066.3", "url": "https://www.ensembl.org/id/ENSBTAP00000043066.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-70171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70171", "resource": "Reactome", "description": "Glycolysis" }, { "id": "R-BTA-70263", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70263", "resource": "Reactome", "description": "Gluconeogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q3AEZ3-1", "protein_name": "Enolase 4", "gene_name": "ENO4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEADTDVRLRREAAEYYRAHRVPQRMEEALNALFPLRPADLYGELANYFSKFSRAPVVCKLAGRKVLDGVGQPTLEVEIYCTVKNYEKRICSAIISSHYQIPENAFSEATEADERERNDSVTTAVEWVNESLSAMLRDLKPTDQCEIDKMLGEYFSKKVEEKKEVEKEEEEEDTLSITSCIPSAVAQSGQKKEAKPGKKSSTEITIPPAEPSESVLCGSLAIGGTSLAIAKAGASINHVPLYLHIALLKRSQDSPKEMTLPLPMVTLLSYEKLSPAKLKLMKEVMLIPPVQLSLKQGIERALDIQKEMMRLLEPAGKAQLSPQLADSKKGRAHNKEKKASPPALNGVSHLGCLITGCDNLEQPLLLIQTACNNIGLELGTDMYLAINCAAHELMDYVKGKYEILTGTFRSPDEMVDMYVELVNKFPSIIALVDPLRKEDRQQWNNMCCALGSKCYLIAEDAATNSSKLKTDHNINIPMCSGVVLKYVNQTKVSDLIELTGLLDGQRRITILGSPDGESSDDSLVDLAVGLGARFVKLGGLSRGERVTKYNRLLAIEEELAKNRTLRYDADFEFTDFAEESQPEKQQPEVLPPLQQDSAPSQPSVPALQGHSMPAQLLESSTLT", "length": 623 }, "evidence": [ { "id": "F6RG16", "url": "https://omabrowser.org/oma/group/F6RG16/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6NNW6-3", "protein_name": "Enolase 4", "gene_name": "ENO4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEEGGGRSCGTTRELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTICKIVGKDVLDGLGLPTLQVDIFCTIQNFPKNVCSVVISTHFEVHENALPELAKAEEAERASAVSTAVQWVNSTITHELQGMAPSDQAEVDHLLRIFFASKVQEDKGRKELEKSLEYSTVPTPLPPVPPPPPPPPPTKKKGQKPGRKDTITEKPIAPAEPVEPVLSGSMAIGAVSLAVAKACAMLLNKPLYLNIALLKHNQEQPTTLSMPLLMVSLVSCGKSSSGKLNLMKEVICIPHPELTTKQGVEMLMEMQKHINKIIEMPSPPKAETKKGHDGSKRGQQQITGKMSHLGCLTINCDSIEQPLLLIQEICANLGLELGTNLHLAINCAGHELMDYNKGKYEVIMGTYKNAAEMVDLYVDLINKYPSIIALIDPFRKEDSEQWDSIYHALGSRCYIIAGTASKSISKLLEQGNISIPKSNGLIIKHTNQTTMSDLVEITNLIDSKKHITVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFKEEHTFFYFNEEAEKAAEALEAAAAREPLVPTFPTQGVEESAETGASSG", "length": 625 }, "evidence": [ { "id": "F6RG16", "url": "https://omabrowser.org/oma/group/F6RG16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZRT2-1", "protein_name": "Enolase 4", "gene_name": "Eno4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEEGGGRSGGISRDLLKLKQQAMAYYQENDVPRKLEELLNSTFYLQPADVYGHLANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICSVAIPTHSEVVENALPEMVDADEAERQQAVSKAVRWINQFITEELWGLIPSNQAEVDRRLRIFFEHKVQADKDRKELERSQEEPVPMTLPVILPPPPPPPSKKKGQKAGRRDTLLEKPIFPPEPPEPVLHGSMAIGAVSLAVAKTSATLAGTPLYLTLALLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVMCIPSPGLTTKQGIELLLEIQKQVNRAMETLPPPKPETKKGHNGGKRSQPPITGRASHLGCLTINYDTIEQPLLLIQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVGTYKSAAEMVELYVDLINKYPSIIALIDPFRKEDSEQWDSLYAAVASRCYLIAGAASRSVSRLLEDRNISLLKYHGLIIKHTNQTTMSDLVEITHLINGKKHLAVFGSTDSESSDDSLVDLAVGLGARFIKLGGLSRGERMTKYNRLLAIEEELIQSGAWGFSEEHNFSFFQEDATTTTAEETLEPLDSIFPTEVIEESAKT", "length": 614 }, "evidence": [ { "id": "F6RG16", "url": "https://omabrowser.org/oma/group/F6RG16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C042-1", "protein_name": "Enolase 4", "gene_name": "Eno4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDEDGGRRGGITRDLQKLKQQAMAYYQENDVPRKLEDLLNSTFYLQPADVYGHLKANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICAVAIPTHFEVVENALPEALDAEDSERAQAVNTAVQWINQSITEELWGLVPSNQAEVDHRLRTFFEHKVQEDKERKELEKSQEELVPAPPPVTLPPPPPPPPPPPSKKKGQKAGRRDTLLEKPVSPPEPPEPVLHGSMAIGAVSLAVAKASATLASDPLYLTLASLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVICIPSPGLTAKQSVELLLEIQKQVNRAMETLPPPKQETKKGHNGSKRAQPPITGKVSHLGCLTINYDAIEQPLLLLQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVGTHKSAAEMVELYVDLINKYPSIIALIDPFRKEDAEQWDSLYAALASRCYLIAGAASGSVSKLLECRNISTLKSHGLIIKHTNQTTMSDLVEITHLINGKKLLAVFGSTDSESSDDSLVDLAVGFGARFIKLGGLSRGERMTKYNRLLAIEEELIQRGVWGFSEEHNFSFFQEDATATMAEETLGLLDSIFPTEVIEESAKT", "length": 619 }, "evidence": [ { "id": "F6RG16", "url": "https://omabrowser.org/oma/group/F6RG16/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F6RG16", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ], "pmid": "" }, { "name": "phosphopyruvate hydratase activity", "id": "GO:0004634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004634", "evidence": [ { "database": "UniProtKB", "id": "F6RG16", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "F6RG16", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "phosphopyruvate hydratase complex", "id": "GO:0000015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000015", "evidence": [ { "database": "UniProtKB", "id": "F6RG16", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10164", "name": "", "equation": "(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RG16-1", "Q3ZC09-1", "Q9XSJ4-1", "F1MB08-1" ], "evidence": [ { "id": "10164", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10164" } ] }, { "id": "R-BTA-70494", "name": "Enolase dimers (ENO1,2,3) convert PEP to 2PG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB08-1", "F6RG16-1", "Q3ZC09-1" ], "evidence": [ { "id": "R-BTA-70494", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70494" } ] }, { "id": "R-BTA-71660", "name": "Enolase dimers dehydrates 2PG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-30485" ], "output_participant_list": [ "R-ALL-29492" ], "enzyme_list": [ "F1MB08-1", "F6RG16-1", "Q3ZC09-1" ], "evidence": [ { "id": "R-BTA-71660", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71660" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29492", "participant_name": "PEP [cytosol]", "crossref": [ { "id": "73-89-2", "database": "CAS", "url": "" }, { "id": "c00074", "database": "KEGG Gene", "url": "" }, { "id": "PHOSPHO-ENOL-PYRUVATE", "database": "AraCyc", "url": "" }, { "id": "ZINC000003870145", "database": "ZINC", "url": "" }, { "id": "C00074", "database": "KEGG Gene", "url": "" }, { "id": "58702", "database": "ChEBI", "url": "" }, { "id": "3674425", "database": "PubChem Compound", "url": "" }, { "id": "138-08-9", "database": "CAS", "url": "" } ] }, { "participant_id": "R-ALL-30485", "participant_name": "2PG [cytosol]", "crossref": [ { "id": "58289", "database": "ChEBI", "url": "" }, { "id": "ZINC000003869232", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F1MB08", "gene_name": "ENO1", "activity": [ { "ec_number": "4.2.1.11", "activity": "(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O.", "evidence": [ { "id": "F1MB08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB08" } ] }, { "ec_number": "4.2.1.11", "activity": "", "evidence": [ { "id": "F1MB08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB08" } ] } ] }, { "uniprot_ac": "F6RG16", "gene_name": "ENO4", "activity": [ { "ec_number": "4.2.1.11", "activity": "(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O.", "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ] }, { "ec_number": "4.2.1.11", "activity": "", "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16" } ] } ] }, { "uniprot_ac": "Q3ZC09", "gene_name": "ENO3", "activity": [ { "ec_number": "4.2.1.11", "activity": "(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O.", "evidence": [ { "id": "Q3ZC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC09" } ] }, { "ec_number": "4.2.1.11", "activity": "", "evidence": [ { "id": "Q3ZC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC09" } ] } ] }, { "uniprot_ac": "Q9XSJ4", "gene_name": "ENO1", "activity": [ { "ec_number": "4.2.1.11", "activity": "(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O.", "evidence": [ { "id": "Q9XSJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XSJ4" } ] }, { "ec_number": "4.2.1.11", "activity": "", "evidence": [ { "id": "Q9XSJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XSJ4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RG16-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 613, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RG16-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RG16" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16" }, { "id": "SM01192", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enolase C-terminal TIM barrel", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 577, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG16" }, { "id": "SM01193", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enolase N-terminal", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 260, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.11", "ec_name": "(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O.", "evidence": [ { "id": "4.2.1.11", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.11" }, { "id": "4.2.1.11", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.11" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 570, "end_pos": 572 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RJ01-1", "uniprot_ac": "F6RJ01", "uniprot_id": "F6RJ01_BOVIN", "mass": { "chemical_mass": 36980.0, "monoisotopic_mass": 36980.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Trans-golgi network protein 2", "type": "recommended", "evidence": [ { "id": "F6RJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RJ01/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RJ01", "url": "https://www.uniprot.org/uniprotkb/F6RJ01" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F6RJ01", "locus": {} } ], "crossref": [ { "id": "F6RJ01", "url": "https://alphafold.ebi.ac.uk/entry/F6RJ01", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038116", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038116", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "PTHR23211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23211:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23211:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6RJ01", "url": "https://www.uniprot.org/uniprotkb/F6RJ01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJ01-1", "url": "https://www.uniprot.org/uniprotkb/F6RJ01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SLLACPNLATSPLASTPLPFARCNVPRSPFSPSTSLQPDSFSVSGLLLSSAPVPGTAAPKDDQASAGSSREHVLIAQSGQENSNQTFLNQTDAKIGPDNSGKRPADTGFDKLGAKERPSETHSDNSGAKQHPGETGSDNSGTKQHPGRADPGSSPRDQSNKLVSSPSSDNKESTKLHVNTVTGKALQTSRTEPGGKVLADPSSPQQEGEGKPLELTEDVEPKETEEGDTEPEEDAPPKEEKEMVGPASRENREGTLSNTWSKKDDLYKDKLGNASAESSHFFAYLVTAAILVAALYIAYHNKRKIIAFVLEGKRSKVTRRPKATDYQRLDQKVREEGGIRHLRCT", "length": 345, "header": "tr|F6RJ01-1|F6RJ01_BOVIN Isoform 1 of Trans-golgi network protein 2 OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=F6RJ01-1" }, "isoforms": [ { "isoform_ac": "F6RJ01-1", "url": "https://www.uniprot.org/uniprotkb/F6RJ01/entry", "sequence": { "sequence": "SLLACPNLATSPLASTPLPFARCNVPRSPFSPSTSLQPDSFSVSGLLLSSAPVPGTAAPKDDQASAGSSREHVLIAQSGQENSNQTFLNQTDAKIGPDNSGKRPADTGFDKLGAKERPSETHSDNSGAKQHPGETGSDNSGTKQHPGRADPGSSPRDQSNKLVSSPSSDNKESTKLHVNTVTGKALQTSRTEPGGKVLADPSSPQQEGEGKPLELTEDVEPKETEEGDTEPEEDAPPKEEKEMVGPASRENREGTLSNTWSKKDDLYKDKLGNASAESSHFFAYLVTAAILVAALYIAYHNKRKIIAFVLEGKRSKVTRRPKATDYQRLDQKVREEGGIRHLRCT", "length": 345, "header": "tr|F6RJ01-1|F6RJ01_BOVIN Isoform 1 of Trans-golgi network protein 2 OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=F6RJ01-1" }, "locus": { "chromosome": "11", "start_pos": 49664860, "end_pos": 49661820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027753.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027753.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027753.7", "url": "https://www.ensembl.org/id/ENSBTAP00000027753.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" }, { "id": "R-BTA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" }, { "id": "R-BTA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-BTA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "F6RJ01", "url": "https://www.uniprot.org/uniprotkb/F6RJ01" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F6RJ01", "url": "https://www.uniprot.org/uniprotkb/F6RJ01" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "F6RJ01", "url": "https://www.uniprot.org/uniprotkb/F6RJ01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RJ01-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 345, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RJ01-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RJ01" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 273, "end_pos": 275 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RLA2-1", "uniprot_ac": "F6RLA2", "uniprot_id": "F6RLA2_BOVIN", "mass": { "chemical_mass": 37274.0, "monoisotopic_mass": 37274.0 }, "refseq": { "ac": "NP_001178274", "name": "testis-specific serine/threonine-protein kinase 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178274" }, "gene_names": [ { "name": "TSSK4", "type": "recommended", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "name": "TSSK4", "type": "synonym", "evidence": [ { "id": "NP_001178274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178274" } ] } ], "protein_names": [ { "name": "Testis-specific serine/threonine-protein kinase 4", "type": "recommended", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2/entry#names_and_taxonomy" } ] }, { "name": "testis-specific serine/threonine-protein kinase 4", "type": "synonym", "evidence": [ { "id": "NP_001178274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178274" } ] } ], "function": [ { "annotation": "Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'.", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2#function" }, { "database": "UniProtKB", "id": "ARBA00055033", "url": "https://www.uniprot.org/uniprotkb/ARBA00055033#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TSSK4", "url": "https://www.uniprot.org/uniprotkb/F6RLA2", "locus": { "chromosome": "10", "start_pos": 20949085, "end_pos": 20955298, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002710", "url": "https://www.ensembl.org/id/ENSBTAG00000002710" } ] } } ], "crossref": [ { "id": "F6RLA2", "url": "https://alphafold.ebi.ac.uk/entry/F6RLA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002710", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002710", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14162", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14162", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539477", "url": "https://www.ncbi.nlm.nih.gov/gene/539477", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539477", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539477", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWIQHYG", "url": "https://omabrowser.org/oma/group/EWIQHYG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RLA2", "url": "https://www.orthodb.org/?gene=F6RLA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLA2-1", "url": "https://www.uniprot.org/uniprotkb/F6RLA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKGDMEAPPTSAYRSVMEEYGYEVGKVIGNGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSNQSVRNSPSYRQMNCFSHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLKETQKEVTFPPNYAISQECKNLILQTLRQAPKRATILDIIKDPWVLKFQPEQPTHEIRLLEAMCQPPSTTNRHQSLEIST", "length": 326, "header": "tr|F6RLA2-1|F6RLA2_BOVIN Isoform 1 of Testis-specific serine/threonine-protein kinase 4 OS=Bos taurus OX=9913 GN=TSSK4 PE=3 SV=1 CANONICAL=F6RLA2-1" }, "isoforms": [ { "isoform_ac": "F6RLA2-1", "url": "https://www.uniprot.org/uniprotkb/F6RLA2/entry", "sequence": { "sequence": "MGKGDMEAPPTSAYRSVMEEYGYEVGKVIGNGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSNQSVRNSPSYRQMNCFSHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLKETQKEVTFPPNYAISQECKNLILQTLRQAPKRATILDIIKDPWVLKFQPEQPTHEIRLLEAMCQPPSTTNRHQSLEIST", "length": 326, "header": "tr|F6RLA2-1|F6RLA2_BOVIN Isoform 1 of Testis-specific serine/threonine-protein kinase 4 OS=Bos taurus OX=9913 GN=TSSK4 PE=3 SV=1 CANONICAL=F6RLA2-1" }, "locus": { "chromosome": "10", "start_pos": 20955070, "end_pos": 20952948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047143.3", "url": "https://www.ensembl.org/id/ENSBTAT00000047143.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044369.2", "url": "https://www.ensembl.org/id/ENSBTAP00000044369.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:539477", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539477", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2QC55-1", "protein_name": "Testis-specific serine/threonine-protein kinase 4", "gene_name": "Tssk4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKGDTSETASATPAYRSVMEEYGYEVGKVIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACSETLAGKWFSQMALGIAYLHSKGIVHRLTPSLSAAGRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVRSSPSYRQMNCLSHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQKEVTFPANLTISQECKGSSIKPGPQPPSPE", "length": 292 }, "evidence": [ { "id": "F6RLA2", "url": "https://omabrowser.org/oma/group/F6RLA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7KFV8-1", "protein_name": "Testis-specific serine/threonine-protein kinase 4", "gene_name": "Tssk4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKGDTLETASLTPAYRSVMEEYGYEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACSETLAGKWFSQMALGIAYLHSKGIVHRLTPSLSAAGRDLKLENLLLDKRENVKISDFGFSKMVMVPSNQPVRSSPSYLQMSGLSHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVMFPTNLSVSLECKNLIFQMLRQAAKRANILDVLKDPWMLKFQSEQPTNEIRMLEAMCQPTTSTTNRHKSLEVTV", "length": 341 }, "evidence": [ { "id": "F6RLA2", "url": "https://omabrowser.org/oma/group/F6RLA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LBD3-1", "protein_name": "Testis-specific serine/threonine-protein kinase 4", "gene_name": "TSSK4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKGDTLESAPPATAYRSVMEEYGYEVGKVIGNGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQMTLGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSNQPVRSSPSYRQMNCFNHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLKETQKEVTFPPSYAISQECKNLVLQTLRQATKRATILDIIKDPWVLKFQPEQATHEIRLLEAMCQPPSTTHRHQSLEIST", "length": 328 }, "evidence": [ { "id": "F6RLA2", "url": "https://omabrowser.org/oma/group/F6RLA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6SA08-1", "protein_name": "Testis-specific serine/threonine-protein kinase 4", "gene_name": "TSSK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT", "length": 328 }, "evidence": [ { "id": "F6RLA2", "url": "https://omabrowser.org/oma/group/F6RLA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D411-1", "protein_name": "Testis-specific serine/threonine-protein kinase 4", "gene_name": "Tssk4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKGDTSETASATPAYRSVMEEYGYEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQKEVTFPANLTISQECKNLILQLLRQSTKRATILDVLRDPWMLKFQPEQPSNEIRLLEAMYQPTSSAKRHQSLEITT", "length": 328 }, "evidence": [ { "id": "F6RLA2", "url": "https://omabrowser.org/oma/group/F6RLA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "F6RLA2", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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}, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": 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"lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 291, "start_aa": "Tyr", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31345:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31345:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RMS7", "url": "https://www.uniprot.org/uniprotkb/F6RMS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RMS7-1", "url": "https://www.uniprot.org/uniprotkb/F6RMS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FETFQVV", "url": "https://omabrowser.org/oma/group/FETFQVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10339:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10339:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005216247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216247", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19149", "url": "https://www.rhea-db.org/rhea/19149", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6RR68", "url": "https://www.uniprot.org/uniprotkb/F6RR68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RR68-1", "url": "https://www.uniprot.org/uniprotkb/F6RR68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSPAVMSLLLVSMGLMEALQAQSHPVIRRDLLSREMPLDMALASFDDQYAGCATAMAAALPELNRTEFQANKVYPDGWVQASSQWRERQAWGPEWGVSPTRLLAPLGFREEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLQHFSFKTLHFLLTEALQLLSSGQRPPQCHQVFRGVQGLRFRPAGPGATVRLGGFASASLQDAAAQHFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRPAQGPSRIYLRAVGKRSTYNCEYIKDKQCKSERCRLGNSAVGQSPLSAVWSLLLLLWFLVGEVFPESPGFL", "length": 326, "header": "tr|F6RR68-1|F6RR68_BOVIN Isoform 1 of NAD(P)(+)--arginine ADP-ribosyltransferase OS=Bos taurus OX=9913 GN=ART1 PE=3 SV=2 CANONICAL=F6RR68-1" }, "isoforms": [ { "isoform_ac": "F6RR68-1", "url": "https://www.uniprot.org/uniprotkb/F6RR68/entry", "sequence": { "sequence": "MQSPAVMSLLLVSMGLMEALQAQSHPVIRRDLLSREMPLDMALASFDDQYAGCATAMAAALPELNRTEFQANKVYPDGWVQASSQWRERQAWGPEWGVSPTRLLAPLGFREEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLQHFSFKTLHFLLTEALQLLSSGQRPPQCHQVFRGVQGLRFRPAGPGATVRLGGFASASLQDAAAQHFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRPAQGPSRIYLRAVGKRSTYNCEYIKDKQCKSERCRLGNSAVGQSPLSAVWSLLLLLWFLVGEVFPESPGFL", "length": 326, "header": "tr|F6RR68-1|F6RR68_BOVIN Isoform 1 of NAD(P)(+)--arginine ADP-ribosyltransferase OS=Bos taurus OX=9913 GN=ART1 PE=3 SV=2 CANONICAL=F6RR68-1" }, "locus": { "chromosome": "15", "start_pos": 51369490, "end_pos": 51365648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008325.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008325.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008325.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008325.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZJK0-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKIPAMMSLLLVSVGLRDGVQVQSYSISQLDIFSQETPLDMAPASFDDQYAGCLADMTAALPDLNHSEFQANKVYADGWALANIQWQDRRAWGSLWGSLPPPPPGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLRNHRSPGCRQVYRGVHGLRFRPAGPGATVRLGGFASASLKNVAAQQFGEDTFFGIWTCLGAPIRGYSFFPEEEEVLIPPFETFQVINTSRPAQGPARIYLRALGKRSTYNCEYIKEKKCRSGPCWLNSSAPGSLSASWSLLLLVLFLMLRALPENPGLRC", "length": 321 }, "evidence": [ { "id": "F6RR68", "url": "https://omabrowser.org/oma/group/F6RR68/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P52961-1", "protein_name": "GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1", "gene_name": "ART1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQMPAMMSLLLVSVGLMEALQAQSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNSAMGQSPLSAVWSLLLLLWFLVVRAFPDGPGLL", "length": 327 }, "evidence": [ { "id": "F6RR68", "url": "https://omabrowser.org/oma/group/F6RR68/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60935-1", "protein_name": "GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1", "gene_name": "Art1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIPAMMSLLLVSVGLRDGVQVQSYSISQLDIFSQETPLDMAPASFDDQYAGCLADMTAALPDLNHSEFQANKVYADGWAQANNQWQERRAWGSVWGSLPPSPPGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLRSHRSRGCQQVYRGVHGLRFRPAGPGATVRLGGFASASLKNVAAQQFGEDTFFGIWTCLGAPIRGYSFFPEEEEVLIPPFETFQVINTSRPTQGPARIYLRALGKRSTYNCEYIKEKKCRSGPCWLGSSAPGSISASCSLLLLLLFLVLSALPENPGLQQLTRC", "length": 325 }, "evidence": [ { "id": "F6RR68", "url": "https://omabrowser.org/oma/group/F6RR68/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F6RR68", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RR68", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "F6RR68", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "F6RR68", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ], "pmid": "" }, { "name": "NAD+-protein-arginine ADP-ribosyltransferase activity", "id": "GO:0106274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106274", "evidence": [ { "database": "UniProtKB", "id": "F6RR68", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19149", "name": "", "equation": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RR68-1", "E1BAP6-1", "E1BI74-1", "A0AAA9S718-1", "A0A3Q1MF93-1", "F1MHV9-1", "Q0VC22-1", "A0A3Q1MZC4-1", "A0AAA9SJA1-1" ], "evidence": [ { "id": "19149", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19149" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MF93", "gene_name": "LOC112441637", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A3Q1MF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF93" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MF93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF93" } ] } ] }, { "uniprot_ac": "A0A3Q1MZC4", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0A3Q1MZC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC4" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MZC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC4" } ] } ] }, { "uniprot_ac": "A0AAA9S718", "gene_name": "SMCO3", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0AAA9S718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S718" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0AAA9S718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S718" } ] } ] }, { "uniprot_ac": "A0AAA9SJA1", "gene_name": "SIRT6", "activity": [ { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "A0AAA9SJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA1" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "A0AAA9SJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA1" } ] } ] }, { "uniprot_ac": "E1BAP6", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "E1BAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAP6" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "E1BAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAP6" } ] } ] }, { "uniprot_ac": "E1BI74", "gene_name": "", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "E1BI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI74" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "E1BI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI74" } ] } ] }, { "uniprot_ac": "F1MHV9", "gene_name": "LOC618664", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "F1MHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHV9" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "F1MHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHV9" } ] } ] }, { "uniprot_ac": "F6RR68", "gene_name": "ART1", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "F6RR68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "F6RR68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RR68" } ] } ] }, { "uniprot_ac": "Q0VC22", "gene_name": "ART5", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "Q0VC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC22" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "Q0VC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC22" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RR68-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 326, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RR68-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RR68" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.2.31", "ec_name": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "2.4.2.31", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.2.31" }, { "id": "2.4.2.31", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.2.31" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204511" } ] } ], "protein_names": [ { "name": "Zinc finger Ran-binding domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "F6RSB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RSB3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger Ran-binding domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005204511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204511" } ] } ], "function": [ { "annotation": "Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. 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May interfere with constitutive 5'-splice site selection.", "evidence": [ { "database": "UniProtKB", "id": "F6RSB3", "url": "https://www.uniprot.org/uniprotkb/F6RSB3#function" }, { "database": "UniProtKB", "id": "ARBA00093412", "url": "https://www.uniprot.org/uniprotkb/ARBA00093412#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RSB3", "url": "https://www.uniprot.org/uniprotkb/F6RSB3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZRANB2", "url": "https://www.uniprot.org/uniprotkb/F6RSB3", "locus": { "chromosome": "3", "start_pos": 74162989, "end_pos": 74145889, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002627", "url": "https://www.ensembl.org/id/ENSBTAG00000002627" } ] } } ], "crossref": [ { "id": "F6RSB3", 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"PTHR12999:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12999:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005204511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005204511", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6RSB3", "url": "https://www.uniprot.org/uniprotkb/F6RSB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RSB3-1", "url": "https://www.uniprot.org/uniprotkb/F6RSB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSSKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERHHRSPSGSSHSGSRSSSKKK", "length": 330, "header": "tr|F6RSB3-1|F6RSB3_BOVIN Isoform 1 of Zinc finger Ran-binding domain-containing protein 2 OS=Bos taurus OX=9913 GN=ZRANB2 PE=3 SV=1 CANONICAL=F6RSB3-1" }, "isoforms": [ { "isoform_ac": "F6RSB3-1", "url": "https://www.uniprot.org/uniprotkb/F6RSB3/entry", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSSKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERHHRSPSGSSHSGSRSSSKKK", "length": 330, "header": "tr|F6RSB3-1|F6RSB3_BOVIN Isoform 1 of Zinc finger Ran-binding domain-containing protein 2 OS=Bos taurus OX=9913 GN=ZRANB2 PE=3 SV=1 CANONICAL=F6RSB3-1" }, "locus": { "chromosome": "3", "start_pos": 74162985, "end_pos": 74146776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003402.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003402.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003402.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003402.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6Z7B1-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "zranb2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGKSFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCGNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENLVYNEREESDGEYDEFGRIKKKFRGKTKKDSDKKEEPKKVDQDDEEEDDDDEDGDLSKYKLDDDDEDDDDDDDDEDDADLSKYDLDDGDEKKGSHSGSSRSSSRSSSSSSRSRSRSRSRSSSSSRSRSRSRSKSRSSSRSGKGSASSKKRSRSPSSSPEGGQKRSRSRSSSGGRKKRRARSHSSERFGVTHGVLDTRRPSALYTGLSDKTVHD", "length": 324 }, "evidence": [ { "id": "F6RSB3", "url": "https://omabrowser.org/oma/group/F6RSB3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35986-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "Zranb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSHSGSREHSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERDRKRSRSRPSSPAVRKKRRTRSRSPERHHRSSSGSTHSGSRSSSKKK", "length": 330 }, "evidence": [ { "id": "F6RSB3", "url": "https://omabrowser.org/oma/group/F6RSB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95218-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "ZRANB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK", "length": 330 }, "evidence": [ { "id": "F6RSB3", "url": "https://omabrowser.org/oma/group/F6RSB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q19QU3-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "ZRANB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSTSRERSRSRGSKSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSTGDPKKRRTRSRSPERHHRSSSGSSHSGSRSSSKKK", "length": 328 }, "evidence": [ { "id": "F6RSB3", "url": "https://omabrowser.org/oma/group/F6RSB3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5ZLX5-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "ZRANB2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCGNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKPVGPASILKEVEDKESEGEDEEDEDGDLSKYKLDEDEDEDDADLSKYNLDASEEEDTNKKKKSNRRSRSKSRSSHSRSSSRSSSHSSSRSRSRSHSRSSSSSRSRSRSSSREHSRSRGSKSRSSSRSYRGSSTPRKRSYSSSRSSSSPERSKKRSRSRSSSSGDRKKRRSRSRSPERRRRSSSGSSHSGSRTSSKKK", "length": 334 }, "evidence": [ { "id": "F6RSB3", "url": "https://omabrowser.org/oma/group/F6RSB3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9AST1-1", "protein_name": "Transcription initiation factor TFIID subunit 15", "gene_name": "TAF15", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGYPTNGSVYVSNLPLGTDENMLADYFGTIGLLKRDKRTGTPKVWLYRDKETDEPKGDATVTYEDPHAALAAVEWFNNKDFHGNTIGVFMAESKNKNAGDAVEFVEFDGGAEETNGGAGRGRGQADSSAKPWQQDGDWMCPNTSCTNVNFAFRGVCNRCGTARPAGASGGSMGAGRGRGRGGGADGGAPGKQPSGAPTGLFGPNDWACPMCGNVNWAKRLKCNICNTNKPGQNEGGVRGGRGGGYKELDEQELEETKRRRREAEEDDGEMYDEFGNLKKKYRVKTNQADTRPAVAAGRAGWEVEELGIDKDGRERSRDRQRDRGRDHHYDKDRRRSRSRERERGKERDYDYDHDRDRDRDYGRERGSRYRN", "length": 372 }, "evidence": [ { "id": "F6RSB3", "url": "https://omabrowser.org/oma/group/F6RSB3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9R020-1", "protein_name": "Zinc finger Ran-binding domain-containing protein 2", "gene_name": "Zranb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSHSGSREHSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERDRKRSRSRPSSPAVRKKRRTRSRSPERHHRSSSGSTHSGSRSSSKKK", "length": 330 }, "evidence": [ { "id": "F6RSB3", "url": "https://omabrowser.org/oma/group/F6RSB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6RSB3", "url": "https://www.uniprot.org/uniprotkb/F6RSB3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RSB3", "url": "https://www.uniprot.org/uniprotkb/F6RSB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RSB3", "url": "https://www.uniprot.org/uniprotkb/F6RSB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "F6RSB3", "url": "https://www.uniprot.org/uniprotkb/F6RSB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RSB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RSB3" }, { "id": "PS50199", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RanBP2-type", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 40, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"tr|F6RW79-1|F6RW79_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Bos taurus OX=9913 GN=USP11 PE=3 SV=1 CANONICAL=F6RW79-1" }, "locus": { "chromosome": "X", "start_pos": 85619298, "end_pos": 85604644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022310.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022310.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022310.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022310.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RW79", "url": "https://www.uniprot.org/uniprotkb/F6RW79" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", 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"https://www.uniprot.org/uniprotkb/F6RW79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RW79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RW79" }, { "id": "PS51283", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51283" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUSP", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 174, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RW79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RW79" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 298, "end_pos": 924, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [], "sequence_features": { 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}, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RWJ0-1", "uniprot_ac": "F6RWJ0", "uniprot_id": "F6RWJ0_BOVIN", "mass": { "chemical_mass": 51951.0, "monoisotopic_mass": 51951.0 }, "refseq": {}, "gene_names": [ { "name": "TRMT12", "type": "recommended", "evidence": [ { "id": "F6RWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ] } ], "protein_names": [ { "name": "tRNA wybutosine-synthesizing protein 2 homolog", "type": "recommended", "evidence": [ { "id": "F6RWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.114", "type": "synonym", "evidence": [ { "id": "F6RWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0/entry#names_and_taxonomy" } ] }, { "name": "tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase", "type": "synonym", "evidence": [ { "id": "F6RWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.", "evidence": [ { "database": "UniProtKB", "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0#function" }, { "database": "UniProtKB", "id": "ARBA00037786", "url": "https://www.uniprot.org/uniprotkb/ARBA00037786#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRMT12", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0", "locus": { "chromosome": "14", "start_pos": 15614561, "end_pos": 15618723, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020398", "url": "https://www.ensembl.org/id/ENSBTAG00000020398" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020398", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020398", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516516", "url": "https://www.ncbi.nlm.nih.gov/gene/516516", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516516", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516516", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EHSWVKH", "url": "https://omabrowser.org/oma/group/EHSWVKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RWJ0", "url": "https://www.orthodb.org/?gene=F6RWJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23245:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23245:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02475", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02475", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25132", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25132", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001019723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36355", "url": "https://www.rhea-db.org/rhea/36355", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWJ0-1", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGCAEAKQREFRGRSRRDCGASNMEGAGGKPTAVVAVVTEPRFTQRYREYLEKHKLLDRQHRVKKLRDGTVALPVLREALLEQHLRELRNRVAPGSTCVPTQLLDPVPSKKAQSYSPAQRLCLEVSRWVEGRGVTWSAELEADLPRSWQRHGDLLLLSEDCFQAKQWRHLEPELWETVASALGAQRLAKRGRVSPDSTRTPAVSLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLPCAGEVLVDLYAGIGYFTLPFLVHAEAAFVHACEWNPHAVVALRNNLELNGVADRCQIHFGDNRKLKLSNVADRVNLGLIPSSEEGWPVACRVLKQDAGGILHIHQNVESFPGKTLQPPGSSEMEEHWPSPHQIISNQLNNGATSDSRRKTLSVATKPEWQRWAKAAETRIATLLHQVHGKRWKTQILHIQPVKSYAPHVDHIVLDLECRPCHLVG", "length": 462, "header": "tr|F6RWJ0-1|F6RWJ0_BOVIN Isoform 1 of tRNA wybutosine-synthesizing protein 2 homolog OS=Bos taurus OX=9913 GN=TRMT12 PE=4 SV=1 CANONICAL=F6RWJ0-1" }, "isoforms": [ { "isoform_ac": "F6RWJ0-1", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0/entry", "sequence": { "sequence": "MRGCAEAKQREFRGRSRRDCGASNMEGAGGKPTAVVAVVTEPRFTQRYREYLEKHKLLDRQHRVKKLRDGTVALPVLREALLEQHLRELRNRVAPGSTCVPTQLLDPVPSKKAQSYSPAQRLCLEVSRWVEGRGVTWSAELEADLPRSWQRHGDLLLLSEDCFQAKQWRHLEPELWETVASALGAQRLAKRGRVSPDSTRTPAVSLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLPCAGEVLVDLYAGIGYFTLPFLVHAEAAFVHACEWNPHAVVALRNNLELNGVADRCQIHFGDNRKLKLSNVADRVNLGLIPSSEEGWPVACRVLKQDAGGILHIHQNVESFPGKTLQPPGSSEMEEHWPSPHQIISNQLNNGATSDSRRKTLSVATKPEWQRWAKAAETRIATLLHQVHGKRWKTQILHIQPVKSYAPHVDHIVLDLECRPCHLVG", "length": 462, "header": "tr|F6RWJ0-1|F6RWJ0_BOVIN Isoform 1 of tRNA wybutosine-synthesizing protein 2 homolog OS=Bos taurus OX=9913 GN=TRMT12 PE=4 SV=1 CANONICAL=F6RWJ0-1" }, "locus": { "chromosome": "14", "start_pos": 15618358, "end_pos": 15616973, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108776.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108776.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085079.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085079.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:516516", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516516", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q4V8B8-1", "protein_name": "tRNA wybutosine-synthesizing protein 2 homolog", "gene_name": "Tyw2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERECEKSVVVAVVTEPRFTQRYRDYLEKQKLLDRQYRVEKLRDGTVALPVLAETLSEHHLQELKNRVAPGSTCKLTQLLDPLPSKKARVCSPAQRLCLEVRRWVEDRGVTWSTELEADLPRSWQRHGDLMLLSEDCFQATQWKRLEPELWETVASALGVQRLAKRGRVLPDGTRTPTVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRKNLEINGVADRCQIHFGDNRKLKLSNTADRVNLGLIPSSEEGWPIACQVLRKDVGGILHIHQNVESFSGKNPQPPGSSNMEKKHWPHPQKITTDKQGNRTTGSCMGEMSSASKPEWQRWAESAESQIASLLHQVHGKPWRTRILHVHPVKSYAPHVDHIVLDLECRPCPLVG", "length": 437 }, "evidence": [ { "id": "F6RWJ0", "url": "https://omabrowser.org/oma/group/F6RWJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q53H54-1", "protein_name": "tRNA wybutosine-synthesizing protein 2 homolog", "gene_name": "TYW2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRENVVVSNMERESGKPVAVVAVVTEPWFTQRYREYLQRQKLFDTQHRVEKMPDGSVALPVLGETLPEQHLQELRNRVAPGSPCMLTQLPDPVPSKRAQGCSPAQKLCLEVSRWVEGRGVKWSAELEADLPRSWQRHGNLLLLSEDCFQAKQWKNLGPELWETVALALGVQRLAKRGRVSPDGTRTPAVTLLLGDHGWVEHVDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLSNIADRVILGLIPSSEEGWPIACQVLRQDAGGILHIHQNVESFPGKNLQALGVSKVEKEHWLYPQQITTNQWKNGATRDSRGKMLSPATKPEWQRWAESAETRIATLLQQVHGKPWKTQILHIQPVKSYAPHVDHIVLDLECCPCPSVG", "length": 448 }, "evidence": [ { "id": "F6RWJ0", "url": "https://omabrowser.org/oma/group/F6RWJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG71-1", "protein_name": "tRNA wybutosine-synthesizing protein 2 homolog", "gene_name": "Tyw2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERECEESVVVAVVTEPRFTQRYRDYLEEQKLLDRLHRVAKLRDGAVALPVLAESLSEQHLQELRDRVAPGSTCVLTRLPDPLPSKKARVRSPAQILCLEVRRWVEDRGVTWSAELEADLPRSWQRHGDLMLLSEDCFQATLWKGLEPELWETVASALGVQRLAKRGRVLPDGTRTPSVTLLLGDHGWVEHMDNGIRYKFDVTQCMFSFGNITEKLRVASLSCAGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVADRCQIHFGDNRKLKLSDIADRVNLGLIPSSKEGWPVACQVLRKDVGGILHIHQNVESFSGKTPQPPGSNNVEKEHWPRPQKITTDTQGNGTTENFRGEISSANKPEWWRWAESAETQIASLLHQVHGKPWRTRILHVHPVKSYAPHVDHIVLDLECRPLTSSWPEGVDLLTQ", "length": 446 }, "evidence": [ { "id": "F6RWJ0", "url": "https://omabrowser.org/oma/group/F6RWJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tRNA methyltransferase activity", "id": "GO:0008175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008175", "evidence": [ { "database": "UniProtKB", "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ], "pmid": "" }, { "name": "tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity", "id": "GO:0102522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102522", "evidence": [ { "database": "UniProtKB", "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ], "pmid": "" }, { "name": "wybutosine biosynthetic process", "id": "GO:0031591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031591", "evidence": [ { "database": "UniProtKB", "id": "F6RWJ0", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36355", "name": "", "equation": "4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RWJ0-1", "Q58D65-1" ], "evidence": [ { "id": "36355", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36355" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F6RWJ0", "gene_name": "TRMT12", "activity": [ { "ec_number": "2.5.1.114", "activity": "4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+).", "evidence": [ { "id": "F6RWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ] }, { "ec_number": "2.5.1.114", "activity": "", "evidence": [ { "id": "F6RWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" } ] } ] }, { "uniprot_ac": "Q58D65", "gene_name": "TYW2", "activity": [ { "ec_number": "2.5.1.114", "activity": "4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+).", "evidence": [ { "id": "Q58D65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D65" } ] }, { "ec_number": "2.5.1.114", "activity": "", "evidence": [ { "id": "Q58D65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D65" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RWJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWJ0" }, { "id": "PS51684", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51684" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM-dependent methyltransferase TRM5/TYW2-type", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 457, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.114", "ec_name": "4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+).", "evidence": [ { "id": "2.5.1.114", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.114" }, { "id": "2.5.1.114", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.114" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RWZ0-1", "uniprot_ac": "F6RWZ0", "uniprot_id": "F6RWZ0_BOVIN", "mass": { "chemical_mass": 90694.0, "monoisotopic_mass": 90694.0 }, "refseq": {}, "gene_names": [ { "name": "CPXM1", "type": "recommended", "evidence": [ { "id": "F6RWZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0" } ] } ], "protein_names": [ { "name": "Probable carboxypeptidase X1", "type": "recommended", "evidence": [ { "id": "F6RWZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0/entry#names_and_taxonomy" } ] }, { "name": "Metallocarboxypeptidase CPX-1", "type": "synonym", "evidence": [ { "id": "F6RWZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in cell-cell interactions. No carboxypeptidase activity was found yet.", "evidence": [ { "database": "UniProtKB", "id": "F6RWZ0", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0#function" }, { "database": "UniProtKB", "id": "ARBA00059461", "url": "https://www.uniprot.org/uniprotkb/ARBA00059461#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RWZ0", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPXM1", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0", "locus": { "chromosome": "13", "start_pos": 52389208, "end_pos": 52381642, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011458", "url": "https://www.ensembl.org/id/ENSBTAG00000011458" } ] } } ], "crossref": [ { "id": "F6RWZ0", "url": "https://alphafold.ebi.ac.uk/entry/F6RWZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011458", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011458", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11308", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11308", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TDRRPCH", "url": "https://omabrowser.org/oma/group/TDRRPCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RWZ0", "url": "https://www.orthodb.org/?gene=F6RWZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RWZ0", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWZ0-1", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGAEMRAESVGAETRGGRSGPSPSSSLPSFPSPPFPTPRLPGSEASERAVGGRAAAAGRGGGLQSPSRKRRTHRPPRAQCVRALDPAMWGLLLALATFAPAVDVGLGAPSTSVLGLASPATTKVPVPTPHSSPAQPSAGKENGTSEQHVRIRVIKKKKIVMKKRKKLTRPTPPVTARPSVTTSPSGTLDLPEKQEPDCPPLGLESLRVSDNQLDASSSQSFGLGPHRGRLNIQSGLEDGDLFDGAWCAEQQDAEPWLQVDARHPTRFSGIITQGRNSIWRYDWVTSYKVQFSNDSRTWWGSKNRSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGASCLRAEILACPVSDPNGLFPEVPMLGSSDSLDFRHHDYKAMRKLMKQVNEQCPNITRIYSIGKSHQGLKLYVMEMSDQPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGDPRVTRLLTETRIHLLPSMNPDGYETAFRRGSELVGWAEGRWNHQGIDLNHNFADLNTPLWEAEDEGLVPDTVPNHHLPLPTYYTLPNATVAPETWAVIKWMQRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDEAVFRWLSTVYAGTNRAMQDPDRRPCHSQDFSLYGSIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVISVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHTVTRSCRVTFEEGPVPCNFRLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQKN", "length": 819, "header": "tr|F6RWZ0-1|F6RWZ0_BOVIN Isoform 1 of Probable carboxypeptidase X1 OS=Bos taurus OX=9913 GN=CPXM1 PE=3 SV=1 CANONICAL=F6RWZ0-1" }, "isoforms": [ { "isoform_ac": "F6RWZ0-1", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0/entry", "sequence": { "sequence": "MRGGAEMRAESVGAETRGGRSGPSPSSSLPSFPSPPFPTPRLPGSEASERAVGGRAAAAGRGGGLQSPSRKRRTHRPPRAQCVRALDPAMWGLLLALATFAPAVDVGLGAPSTSVLGLASPATTKVPVPTPHSSPAQPSAGKENGTSEQHVRIRVIKKKKIVMKKRKKLTRPTPPVTARPSVTTSPSGTLDLPEKQEPDCPPLGLESLRVSDNQLDASSSQSFGLGPHRGRLNIQSGLEDGDLFDGAWCAEQQDAEPWLQVDARHPTRFSGIITQGRNSIWRYDWVTSYKVQFSNDSRTWWGSKNRSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGASCLRAEILACPVSDPNGLFPEVPMLGSSDSLDFRHHDYKAMRKLMKQVNEQCPNITRIYSIGKSHQGLKLYVMEMSDQPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGDPRVTRLLTETRIHLLPSMNPDGYETAFRRGSELVGWAEGRWNHQGIDLNHNFADLNTPLWEAEDEGLVPDTVPNHHLPLPTYYTLPNATVAPETWAVIKWMQRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDEAVFRWLSTVYAGTNRAMQDPDRRPCHSQDFSLYGSIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVISVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHTVTRSCRVTFEEGPVPCNFRLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQKN", "length": 819, "header": "tr|F6RWZ0-1|F6RWZ0_BOVIN Isoform 1 of Probable carboxypeptidase X1 OS=Bos taurus OX=9913 GN=CPXM1 PE=3 SV=1 CANONICAL=F6RWZ0-1" }, "locus": { "chromosome": "13", "start_pos": 52389069, "end_pos": 52382620, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039309.5", "url": "https://www.ensembl.org/id/ENSBTAT00000039309.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039106.4", "url": "https://www.ensembl.org/id/ENSBTAP00000039106.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480KGE1-1", "protein_name": "Probable carboxypeptidase X1", "gene_name": "CPXM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWGLLLALATFAPAVGVSLGAPSASVLGLAPPGTTKAPVPSPAPRSSPTEPPAGKENGTSEHHVRIRVIKKKKIIMKKRKKLTHPRPPVTAGPSVTTSPAGTLDLPEKQEPGCPPLGLESLRVSDNQLDASSSQSFGLGPHRGRLNIQSGLEDGDLFDGAWCAEQQDAEPWLQVDARHPTRFSGVITQGRNSIWRYDWVTSYKVQFSNDSRTWWGSKNRSSGMDAVFPANSDPETPVMNLLPEPQVARFIRLLPQTWLEGGAACLRAEILACPVSDPNSLFPEVPMLGSSDPLDFRHHDYKAMRKLMKQVNEQCPNITRVYSIGKSHQGLKLYVMEMSDQPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGDPRVTRLLTEMRIHLLPSMNPDGYETAFRRGSELVGWAEGRWNHQGIDLNHNFADLNTPLWEAEDDGLVPDTVPNHHLPLPTYYTLPNATVAPETRAVIKWMERIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDEAVFRWLSTVYAGTNRAMQDPDRRPCHSQDFSSYGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHTVTRSCRVTFEEGPVPCNFHLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQKD", "length": 732 }, "evidence": [ { "id": "F6RWZ0", "url": "https://omabrowser.org/oma/group/F6RWZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YU47-1", "protein_name": "Carboxypeptidase X, M14 family member 1", "gene_name": "CPXM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPPPPLALLLLFAAVAAPPAPLGTALRPEAVGMGGPGGSAATTLRGTAPPKGTATTTPRGTAPPKGTATTTPRGTAPPKGTATTPPKGTATTPTKRTERGGPSSAAPTRGGPGPKAPVPRKKVVRVKVVRKKVLKKRPKAPSRSPPAPQEQPCPPLGLESLRVQDSQLRSSSDKRYGLGAHRGRLNIQSGLYDGDFFDGGWCAGREDAGQWLEVDARRLTNFTGVITQGLNSIWTYDWVTSYKVQFSNDTHTWQPCRNGTEEAVFPANKDPETPVLNALPCRAVARYIRINPQSWFENGTICLRAEVLGCAVPDPNNIYQWPEQPAPTDKLDFRHHNYKEMRKLMKRVSEECPNITRIYSIGKSYLGLKMYVMEISDNPGQHEVGEPEFRYVAGMHGNEVLGRELLLNLMEYLCREFRRGNPRVVRLVTGTRIHLLPSMNPDGYETAYRLGSELSGWAMGRWTYEGIDLNHNFADLNTALWDAEDNDLVPHQFPNHYIPIPEYYTFANATVAPETRAVIDWMQRYPFVLSANLHGGELVVTYPFDMTRTYWKAQELTPTADDGVFRWLATVYATSNLAMASEERRLCHYDDFMRSGNIINGANWHTVPGSMNDFSYLHTNCFEITVELSCDKFPHVSELPTEWENNRESLLLYMEQVHRGIKGVVRDEETGEGIANAIISVDGINHDVRTAVDGDYWRLLNPGEYEVTARAEGYEAATRPCRVSFENVPTPCSFRLARRRLRGRGPPDLQLRLHRHRLRRLRAQRRAP", "length": 768 }, "evidence": [ { "id": "F6RWZ0", "url": "https://omabrowser.org/oma/group/F6RWZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZW78-1", "protein_name": "Probable carboxypeptidase X1", "gene_name": "Cpxm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCGGFADCAGPGTGEAGFQGPSLRPPGVLGAHQCGPLPGDLTALRSLPSPLLRPRIPASGCGRAGGCRGAWGGGGRGGRKGRGAPQTPAGRKEPTESLGTVRLPILPAMWGLLLAVTAFAPSVGLGLGAPSASVLGLTPGSTLAPHSSIAQPSTKANETSEQHVRLRVIKKKKIVVKKRKKLRQPGPLVTARPLVTTHPAKTPTLPEKQEPGCPPLGLESLRVSDSQLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEQQDNEPWLQVDARSPARFSGIVTQGRNSVWRYDWVTSFKVQFSNDSQSWWMSRNSSGMDMVFPANSDAETPVLNLLPEPQVARFIRLLPQTWFQGGAPCLRAEILACPVSDPNDLFPEAHTLGSSDSLDFRHHNYKAMRKLMKEVNEQCPNITRIYSIGKSHQGLKLYVMEMSDHPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCREFLRGDPRVTRLLTETRIHLLPSMNPDGYETAYHKALSWQGSELVGWAEGRWTHQGIDLNHNFADLNTQLWYAEDDGLVPHTVPNHHLPLPTYYTLPNATVAPETWAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCHSQDFSLHGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHEKELPQEWENNKDALLTYLEQVRMGITGVVRDKDTELGIADAVIAVEGINHDVTTAWGGDYWRLLTPGDYVVTASAEGYHTAKQHCRVTFEEGPVPCNFLLTKTPKQRLLELLAAGAKLPPDLRRKLEWLRGQK", "length": 835 }, "evidence": [ { "id": "F6RWZ0", "url": "https://omabrowser.org/oma/group/F6RWZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96SM3-1", "protein_name": "Probable carboxypeptidase X1", "gene_name": "CPXM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWGLLLALAAFAPAVGPALGAPRNSVLGLAQPGTTKVPGSTPALHSSPAQPPAETANGTSEQHVRIRVIKKKKVIMKKRKKLTLTRPTPLVTAGPLVTPTPAGTLDPAEKQETGCPPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQKD", "length": 734 }, "evidence": [ { "id": "F6RWZ0", "url": 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"name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6RWZ0", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F6RWZ0", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RWZ0", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "F6RWZ0", "url": "https://www.uniprot.org/uniprotkb/F6RWZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RWZ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 819, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RWZ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RWZ0" } ], "lectin_list": [], "domain_list": [ { 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"uniprot_ac": "F6S1Q0", "uniprot_id": "F6S1Q0_BOVIN", "mass": { "chemical_mass": 47110.0, "monoisotopic_mass": 47110.0 }, "refseq": {}, "gene_names": [ { "name": "KRT18", "type": "recommended", "evidence": [ { "id": "F6S1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0" } ] } ], "protein_names": [ { "name": "Keratin 18", "type": "synonym", "evidence": [ { "id": "F6S1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6S1Q0", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KRT18", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0", "locus": { "chromosome": "5", "start_pos": 26998520, "end_pos": 27002263, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001517", "url": "https://www.ensembl.org/id/ENSBTAG00000001517" } ] } } ], "crossref": [ { "id": "F6S1Q0", "url": "https://alphafold.ebi.ac.uk/entry/F6S1Q0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001517", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001517", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6S1Q0", "url": "https://www.orthodb.org/?gene=F6S1Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6S1Q0", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S1Q0-1", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFSTQSTFSNYRSLGSVQSSGHRVRPVSSAASVYAGAGGSGSRISVSRTTSVRGGWGSGNLGAGMAGGLVGVGGIQGEKETMQDLNDRLASYLEKVRSLESKIREHLEKKGPQVRDWAHYLKIIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVIDDTNVTRLQLETEIEALKEELLFMKKNHEEEVKGLQNQIANSGLTVELDAPKPQDLSKIMADIRAQYDELAQKNREELDKYWSQQIEESTTVVTSQTAEIGAAEMTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYAMQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNVKVKLEAEINTYRRLLEDGEDFSLGDALDSSNSRQTIQKTTTLRLVDGKVVSETSDTKVLRH", "length": 422, "header": "tr|F6S1Q0-1|F6S1Q0_BOVIN Isoform 1 of Keratin 18 OS=Bos taurus OX=9913 GN=KRT18 PE=1 SV=2 CANONICAL=F6S1Q0-1" }, "isoforms": [ { "isoform_ac": "F6S1Q0-1", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0/entry", "sequence": { "sequence": "MSFSTQSTFSNYRSLGSVQSSGHRVRPVSSAASVYAGAGGSGSRISVSRTTSVRGGWGSGNLGAGMAGGLVGVGGIQGEKETMQDLNDRLASYLEKVRSLESKIREHLEKKGPQVRDWAHYLKIIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVIDDTNVTRLQLETEIEALKEELLFMKKNHEEEVKGLQNQIANSGLTVELDAPKPQDLSKIMADIRAQYDELAQKNREELDKYWSQQIEESTTVVTSQTAEIGAAEMTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYAMQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNVKVKLEAEINTYRRLLEDGEDFSLGDALDSSNSRQTIQKTTTLRLVDGKVVSETSDTKVLRH", "length": 422, "header": "tr|F6S1Q0-1|F6S1Q0_BOVIN Isoform 1 of Keratin 18 OS=Bos taurus OX=9913 GN=KRT18 PE=1 SV=2 CANONICAL=F6S1Q0-1" }, "locus": { "chromosome": "5", "start_pos": 27002064, "end_pos": 26998594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001988.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001988.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001988.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001988.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q0", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q0", "url": "https://www.uniprot.org/uniprotkb/F6S1Q0" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": 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"start_pos": 52675269, "end_pos": 52666613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001379.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001379.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001379.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001379.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-111367", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111367", "resource": "Reactome", "description": "SLBP independent Processing of Histone Pre-mRNAs" }, { "id": "R-BTA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-BTA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-BTA-73856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73856", "resource": "Reactome", "description": "RNA Polymerase II Transcription Termination" }, { "id": "R-BTA-77588", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77588", "resource": "Reactome", "description": "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" }, { "id": "R-BTA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-BTA-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "P14678-1", "protein_name": "Small nuclear ribonucleoprotein-associated proteins B and B'", "gene_name": "SNRPB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP", "length": 240 }, "evidence": [ { "id": "G1K134", "url": "https://omabrowser.org/oma/group/G1K134/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17136-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein B", "gene_name": "Snrpb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL", "length": 231 }, "evidence": [ { "id": "G1K134", "url": "https://omabrowser.org/oma/group/G1K134/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P27048-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein B", "gene_name": "Snrpb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGLPPGRGTPMGMPPPGMRPPPPGMRGLL", "length": 231 }, "evidence": [ { "id": "G1K134", "url": "https://omabrowser.org/oma/group/G1K134/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q05856-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein B", "gene_name": "SmB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTIGKNNKMIQHLNYRVRIVLQDSRTFIGTFKAFDKHMNLILGDCEEFRKIRSKNSKVPEREEKRVLGFVLLRGENIVSLTVEGPPPPEEGLPRVPIPGAAPGPGIGRVAGRGMPINLSAVPAGLQGPVRGVGGPAQQHMAPMGRGVPRAPMMGAPPPGMIPGGMPSMPGNMGRGAPPPMRGPPPSMIRGAPPPGRGGY", "length": 199 }, "evidence": [ { "id": "G1K134", "url": "https://omabrowser.org/oma/group/G1K134/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q55A45-1", "protein_name": "Small nuclear ribonucleoprotein-associated protein B", "gene_name": "snrpb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSGMPKSSKMLQYINYRMRVTIQDGRVIVGRFLAFDKHMNVVICDAEEFRRIRQKGKEDREEKRTLGMILIRGETVVSMSVEAPPPEEAKLAATSKMPPQIPGGPGIGRAVGRGMPMGGMGMGGSGPMSGLTGPVRGVGGPAPHSMMPGGGVPPPMGRGGFPPQGFPPGGPSPQGAFNNNPNNNNGGPPQGFPPGGPIGRGGFPPQGFPPGGPMGGPNLNNGNMPPQGFPPGGPMGRGGFPPQGFPPGGPNFNNMPPQGFPPGGPMGRGGFQRK", "length": 274 }, "evidence": [ { "id": "G1K134", "url": "https://omabrowser.org/oma/group/G1K134/", "database": "OMA" } ], 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239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G1K1X9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 442, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G1K1X9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G1K1X9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G1K1X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K1X9" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 129, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G1K1X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K1X9" }, { "id": "PS50998", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50998" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gla", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 93, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "G1K1X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K1X9" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 181, "end_pos": 403, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MVZ9-1", "uniprot_ac": "G3MVZ9", "uniprot_id": "G3MVZ9_BOVIN", "mass": { "chemical_mass": 45541.0, "monoisotopic_mass": 45541.0 }, "refseq": { "ac": "XP_010818065", "name": "lipase member N", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818065" }, "gene_names": [ { "name": "LIPN", "type": "recommended", "evidence": [ { "id": "G3MVZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9" } ] }, { "name": "LIPN", "type": "synonym", "evidence": [ { "id": "XP_010818065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818065" } ] } ], "protein_names": [ { "name": "Lipase", "type": "recommended", "evidence": [ { "id": "G3MVZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9/entry#names_and_taxonomy" } ] }, { "name": "lipase member N", "type": "synonym", "evidence": [ { "id": "XP_010818065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818065" } ] } ], "function": [ { "annotation": "Catalyzes the hydrolysis of triacylglycerols to yield free fatty acids, diacylglycerol, monoacylglycerol, and glycerol. Shows a preferential hydrolysis at the sn-3 position of triacylglycerol.", "evidence": [ { "database": "UniProtKB", "id": "G3MVZ9", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9#function" }, { "database": "UniProtKB", "id": "ARBA00045163", "url": "https://www.uniprot.org/uniprotkb/ARBA00045163#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MVZ9", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LIPN", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9", "locus": { "chromosome": "26", "start_pos": 10462635, "end_pos": 10431267, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024911", "url": "https://www.ensembl.org/id/ENSBTAG00000024911" } ] } } ], "crossref": [ { "id": "G3MVZ9", "url": "https://alphafold.ebi.ac.uk/entry/G3MVZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024911", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024911", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523964", "url": "https://www.ncbi.nlm.nih.gov/gene/523964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523964", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523964", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YACEEHT", "url": "https://omabrowser.org/oma/group/YACEEHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MVZ9", "url": "https://www.orthodb.org/?gene=G3MVZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010818065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818065", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12044", "url": "https://www.rhea-db.org/rhea/12044", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "39931", "url": "https://www.rhea-db.org/rhea/39931", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40047", "url": "https://www.rhea-db.org/rhea/40047", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MVZ9", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MVZ9-1", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLFLTTAYLICGTLNAAGFFNLEKEANPEVWMSTSEIITYNGYPSEEYEVTTQDGYILSVNRIPHGRKDTKITGARPVVYLQHALFSDNTSWLENFANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEKFWAFSFHEMAKYDLPGIIDFIVNKTGQQKLYFVGYSLGTTIGFVAFATMPELAQRIKMNFALGPVVSFKYPTGIFTRFFQLPSSAIKKLFGTKGFFLEESIGKSPSVKICNNKILWVICREFMSLWAGSNKKNMNMSRMDVYMSHAPTGSSIQNILHLKQLYHSDEFRAYDWGSEAENRRHYNQSHPPLYDLTAMKVPTAIWAGGNDILITPRDVARILPQIRNLRYFKLLPDWNHFDFIWGLDAAKRVYSKIIDLMKSYP", "length": 397, "header": "tr|G3MVZ9-1|G3MVZ9_BOVIN Isoform 1 of Lipase OS=Bos taurus OX=9913 GN=LIPN PE=3 SV=2 CANONICAL=G3MVZ9-1" }, "isoforms": [ { "isoform_ac": "G3MVZ9-1", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9/entry", "sequence": { "sequence": "MWLFLTTAYLICGTLNAAGFFNLEKEANPEVWMSTSEIITYNGYPSEEYEVTTQDGYILSVNRIPHGRKDTKITGARPVVYLQHALFSDNTSWLENFANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEKFWAFSFHEMAKYDLPGIIDFIVNKTGQQKLYFVGYSLGTTIGFVAFATMPELAQRIKMNFALGPVVSFKYPTGIFTRFFQLPSSAIKKLFGTKGFFLEESIGKSPSVKICNNKILWVICREFMSLWAGSNKKNMNMSRMDVYMSHAPTGSSIQNILHLKQLYHSDEFRAYDWGSEAENRRHYNQSHPPLYDLTAMKVPTAIWAGGNDILITPRDVARILPQIRNLRYFKLLPDWNHFDFIWGLDAAKRVYSKIIDLMKSYP", "length": 397, "header": "tr|G3MVZ9-1|G3MVZ9_BOVIN Isoform 1 of Lipase OS=Bos taurus OX=9913 GN=LIPN PE=3 SV=2 CANONICAL=G3MVZ9-1" }, "locus": { "chromosome": "26", "start_pos": 10461631, "end_pos": 10440718, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034704.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034704.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034590.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034590.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:523964", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523964", "resource": "KEGG Pathway" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K430-1", "protein_name": "Lipase", "gene_name": "Lipn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVMWLFLTTACLIRGTLSAGGFFENTVNPEVWMNASEIITYNGYPSEEYDVTTADGYILAINRIPHGRGQTGHAGPRPVVYMQHALFADNAYWLENFPNGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEKFWAFSFDEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFIAFSTMPELAQRIKMNFALGPVISFKYPTSIFTSFFLLPRSMIKLMFGTKGFFLEDKNAKMSYVTVCNKKLLRPMCSEFMSLWAGFNKKNMNMSRLDVYMSHAPTGSSIQNILHIKQLYQSDEFRAYDWGSEAENMNHYNQSRPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPEWNHFDFVWGLDAPQRLYSKIIGLMKEYR", "length": 398 }, "evidence": [ { "id": "G3MVZ9", "url": "https://omabrowser.org/oma/group/G3MVZ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3L7HYR2-1", "protein_name": "Lipase", "gene_name": "Lipn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPMMWLFLTTTCLIHETLSVSELFDLENEVNPEVWMNTSEIIIYNGYPSEEYEVTTADGYILTLNRIPHGRAQAGLTGTRPVVYMQHALFADNAYWLENFANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSANEEKFWAFSFDEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFIAFSTMPELAQRIKMNFAMGPVISFKYPTSIFTSFFLLPNSIIKHIFGTKGFFLEDKKAKATYIKVCNRKILRPMCSEFMSLWAGFNKKNMNMSRLDVYMSHAPTGSSIQNILHIKQLYRSDEFRAYDWGSEAENMNHYNQSRPPIYDLTAMKVPTAIWAGGHDALITPQDVARILPQVTNLRYFKLFPDWNHFDFVWGLDAPQRLYSKIIGLMREYL", "length": 400 }, "evidence": [ { "id": "G3MVZ9", "url": "https://omabrowser.org/oma/group/G3MVZ9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1V169-1", "protein_name": "Lipase", "gene_name": "LIPN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMWLFLTTTYLICGTLNAGGYFNLEKEANPEVWMNISEIIEYNGYPSEEYEVTTQDGYILSINRIPHGRRDTKNTGTRPVVYMQHALFADSASWLQNFANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSLTQEEFWAFSFDEMAKYDLPGIVDFIVNKTGQEKLYFVGHSLGTTIGFVAFATIPELAQRIKMNFALGPTISLKYTMGIFTRLFLLPNSAIKKFFGTKGVFLEDKARKSSSIKLCNNKILWVICSEIMSLWAGFNKKNMNMSRMDVYMSHAPTGSSVQNILHIKQLYQSDEFRAYDWGSEAENMRHYNQSRPPLYDLTAMEVPTAIWAGGNDVLVTPQDVARILPQIKNLRYFKLLPDWNHFDFIWGLDAAQRVYSKIIDLMKLYP", "length": 398 }, "evidence": [ { "id": "G3MVZ9", "url": "https://omabrowser.org/oma/group/G3MVZ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3U4B4-1", "protein_name": "Lipase member N", "gene_name": "Lipn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPMMWLFLTTACLIPGTLSAGGFLDFENKVNPEVWMNASEIIMYNGYPSEEYDVTTADGYILAINRIPHGRAQTGQTGPRPVVYMQHALFADNAYWLENFANGSLGFILADAGYDVWMGNSRGNTWSRRHKTLSANEEKFWAFSFNEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPVISFKYPTSVFTNLFLLPKSIIKLVFGTKGVLLEDKNARMSFITFCNQKLLQPLCSEFMSLWAGFNKKNMNMSRLDVYMAHAPTGSSIQNMLHIKQLYRSDEFRAYDWGSEAENMNHYNQSYPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPDWNHFDFVWGLDAPQRLYSKIISLMKEYF", "length": 400 }, "evidence": [ { "id": "G3MVZ9", "url": "https://omabrowser.org/oma/group/G3MVZ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55EU8-1", "protein_name": "Lipase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNILTIEYIIIILVTILISCNVTQSIEDILFDPDFKLNISQLIAKQGYPVENHFVTTKDGYIISLQRIPNGINKNKGIFNNNNNNNNTKIKPTVLLQHGLEDIGTTWVFQENRYQSLGFILADEGYDVWIGNVRGTIYSNKHLEYTVNDDEYWDFTFNEMGEFDLPSMVDYIINVTGNSKVNYIGHSQGTTMGFIGFKDGSELTKKINTFFALAPVARVTHCQSPLFNFLGNLRFGLILKFFGVKSFLMDSPILRGFLAPTLCSITPIACTTSLGFITGWGENSNLNETRLPVILSQSPGGTSTKNIIHWSQNLNNEFQKFDYGSSYENFIHYSQSTPPKYNITNFSKKIPTIIFTGGKDLISTKEDYNWLLPQLKNLIYYKHIDSYSHLDFVWGNDAYKQVYSDILKYLLKYN", "length": 415 }, "evidence": [ { "id": "G3MVZ9", "url": "https://omabrowser.org/oma/group/G3MVZ9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5VXI9-1", "protein_name": "Lipase member N", "gene_name": "LIPN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMWLLLTTTCLICGTLNAGGFLDLENEVNPEVWMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRTHARSTGPRPVVYMQHALFADNAYWLENYANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSETDEKFWAFSFDEMAKYDLPGVIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISFKYPTGIFTRFFLLPNSIIKAVFGTKGFFLEDKKTKIASTKICNNKILWLICSEFMSLWAGSNKKNMNQSRMDVYMSHAPTGSSVHNILHIKQLYHSDEFRAYDWGNDADNMKHYNQSHPPIYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQIKSLHYFKLLPDWNHFDFVWGLDAPQRMYSEIIALMKAYS", "length": 398 }, "evidence": [ { "id": "G3MVZ9", "url": "https://omabrowser.org/oma/group/G3MVZ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "G3MVZ9", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "G3MVZ9", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "G3MVZ9", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "G3MVZ9", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12044", "name": "", "equation": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PK46-1", "A0A3Q1LV96-1", "A0A3Q1MLE6-1", "Q3SZ79-1", "E1BJQ9-1", "Q5EA42-1", "P11151-1", "P16386-1", "P30122-1", "Q29458-1", "Q2KI18-1", "F1MC21-1", "Q0P5B7-1", "A0A3Q1M7B8-1", "F6RA94-1", "G5E5T0-1", "A0A3Q1LR40-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "12044", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12044" } ] }, { "id": "39931", "name": "", "equation": "1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29458-1" ], "evidence": [ { "id": "39931", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39931" } ] }, { "id": "40047", "name": "", "equation": "1,2,3-trioctanoylglycerol + H2O = 1,2-dioctanoyl-sn-glycerol + octanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29458-1" ], "evidence": [ { "id": "40047", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40047" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LR40", "gene_name": "LIPG", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] } ] }, { "uniprot_ac": "A0A3Q1LV96", "gene_name": "PLB1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] } ] }, { "uniprot_ac": "A0A3Q1M7B8", "gene_name": "PNLIPRP1", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1M7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7B8" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1M7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7B8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLE6", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] } ] }, { "uniprot_ac": "A0AAA9S3G3", "gene_name": "LOC100297709", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] } ] }, { "uniprot_ac": "A0ABI0NMZ2", "gene_name": "PNPLA3", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] } ] }, { "uniprot_ac": "A5PK46", "gene_name": "PNLIPRP2", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A5PK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK46" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A5PK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK46" } ] }, { "ec_number": "3.1.1.26", "activity": "a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 a fatty acid + 2 H(+).", "evidence": [ { "id": "A5PK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK46" } ] } ] }, { "uniprot_ac": "E1BJQ9", "gene_name": "PNLIP", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "E1BJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJQ9" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "E1BJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJQ9" } ] } ] }, { "uniprot_ac": "F1MC21", "gene_name": "PNLIPRP3", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "F1MC21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC21" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "F1MC21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC21" } ] } ] }, { "uniprot_ac": "F6RA94", "gene_name": "DAGLB", "activity": [ { "ec_number": "3.1.1.116", "activity": "a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "F6RA94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA94" } ] }, { "ec_number": "3.1.1.116", "activity": "", "evidence": [ { "id": "F6RA94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA94" } ] } ] }, { "uniprot_ac": "G5E5T0", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] } ] }, { "uniprot_ac": "P11151", "gene_name": "LPL", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] }, { "ec_number": "3.1.1.34", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] }, { "ec_number": "3.1.1.34", "activity": "", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] } ] }, { "uniprot_ac": "P16386", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] }, { "ec_number": "3.1.1.79", "activity": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] } ] }, { "uniprot_ac": "P30122", "gene_name": "CEL", "activity": [ { "ec_number": "3.1.1.13", "activity": "a cholesterol ester + H2O = cholesterol + a fatty acid + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.6", "activity": "an acetyl ester + H2O = an aliphatic alcohol + acetate + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.13", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.6", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] } ] }, { "uniprot_ac": "Q0P5B7", "gene_name": "AADAC", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q0P5B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B7" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q0P5B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B7" } ] } ] }, { "uniprot_ac": "Q29458", "gene_name": "LIPF", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q29458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29458" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q29458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29458" } ] } ] }, { "uniprot_ac": "Q2KI18", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] } ] }, { "uniprot_ac": "Q3SZ79", 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"", "evidence": [ { "id": "Q5EA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA42" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "Q5EA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA42" } ] }, { "ec_number": "3.1.1.6", "activity": "", "evidence": [ { "id": "Q5EA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EA42" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MVZ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 397, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MVZ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MVZ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MVZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MVZ9" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 378, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MWG4-1", "uniprot_ac": "G3MWG4", "uniprot_id": "G3MWG4_BOVIN", "mass": { "chemical_mass": 113608.0, 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"database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4#function" }, { "database": "UniProtKB", "id": "ARBA00055883", "url": "https://www.uniprot.org/uniprotkb/ARBA00055883#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IARS2", "url": "https://www.uniprot.org/uniprotkb/G3MWG4", "locus": { "chromosome": "16", "start_pos": 23631281, "end_pos": 23586935, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012582", "url": "https://www.ensembl.org/id/ENSBTAG00000012582" } ] } } ], "crossref": [ { "id": "G3MWG4", "url": "https://alphafold.ebi.ac.uk/entry/G3MWG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012582", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07960", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07960", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HCWRCKT", "url": "https://omabrowser.org/oma/group/HCWRCKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MWG4", "url": "https://www.orthodb.org/?gene=G3MWG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42765", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42765", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42765:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42765:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06827", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06827", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "11060", "url": "https://www.rhea-db.org/rhea/11060", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWG4-1", "url": "https://www.uniprot.org/uniprotkb/G3MWG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRWGLRPRGPGAAALAAAWNLWVPPRLPCRPLWRGTTGSLLVRSVTGASNQPQNSSNGSYRDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKAEFCLHDGPPYANGDPHVGHALNKILKDIANRYHMMRGSKIHFVPGWDCHGLPIEIKVLSELGGKAQNLSAMEIREKARSFAKAAIEKQKLSFIRWGIMADWNNCYYTFDGRYEAKQLRIFYQMYDKGLIYRSYKPVFWSPSSRTALAEAELEYNPEHISRSVYVKFPLLKPSPKLASLLDGSSPVSFLVWTTQPWTIPANQAVCYMPESKYAVVKCSSSGDLYILGADKVTSVASTLGTTFEVISTFSGVDLENGSCAHPLISERESPLLPANHVTMTKGTGLVHTAPAHGMEDYSVAAQHNLSTDCLVNEDGVFTDAAGPELQNKAVLKEGTDAVIMMLQAAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFVNITDIKTTAKELLKKVKFIPGSALNAMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDDVLINSQTIEHIIQLVEEHGSDIWWTLPPEQLLPKEVLSQVGGPDALEYVPGQDILDIWFDSGTSWSNVLPGTDQRADLYLEGKDQLGGWFQSSLLTSVAARNKSPFKTVVVHGFTLGEKGEKMSKSLGNIIDPDVVINGGQDHSKEPPYGADVLRWWVAESNVFTEVTISPSLLNAARDDISKLRNTLRFLLGNVAGFNPETDSIPVNSMYVIDQYMLHLLQDLANKINDSYKQYDFGKVVRLLQAFYTRELSNFYFSIIKDRLYCENADDPKRRSCQTALAEILDVMVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWIKTSSIWKKPGLEEAIESACAMRDSFLGSIPGKNAAEYEVIIVIEPGLLFEIMEMLQAEETSSTSQLNELMMASQTTLLSQEPRGISEDVTELKGTFLINLEGGDIREESSYKVIVMTTTKEKCPRCWKYTAESSDTLCPRCAEVVKGK", "length": 1012, "header": "tr|G3MWG4-1|G3MWG4_BOVIN Isoform 1 of Isoleucine--tRNA ligase, mitochondrial OS=Bos taurus OX=9913 GN=IARS2 PE=3 SV=2 CANONICAL=G3MWG4-1" }, "isoforms": [ { "isoform_ac": "G3MWG4-1", "url": "https://www.uniprot.org/uniprotkb/G3MWG4/entry", "sequence": { "sequence": "MRWGLRPRGPGAAALAAAWNLWVPPRLPCRPLWRGTTGSLLVRSVTGASNQPQNSSNGSYRDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKAEFCLHDGPPYANGDPHVGHALNKILKDIANRYHMMRGSKIHFVPGWDCHGLPIEIKVLSELGGKAQNLSAMEIREKARSFAKAAIEKQKLSFIRWGIMADWNNCYYTFDGRYEAKQLRIFYQMYDKGLIYRSYKPVFWSPSSRTALAEAELEYNPEHISRSVYVKFPLLKPSPKLASLLDGSSPVSFLVWTTQPWTIPANQAVCYMPESKYAVVKCSSSGDLYILGADKVTSVASTLGTTFEVISTFSGVDLENGSCAHPLISERESPLLPANHVTMTKGTGLVHTAPAHGMEDYSVAAQHNLSTDCLVNEDGVFTDAAGPELQNKAVLKEGTDAVIMMLQAAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFVNITDIKTTAKELLKKVKFIPGSALNAMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDDVLINSQTIEHIIQLVEEHGSDIWWTLPPEQLLPKEVLSQVGGPDALEYVPGQDILDIWFDSGTSWSNVLPGTDQRADLYLEGKDQLGGWFQSSLLTSVAARNKSPFKTVVVHGFTLGEKGEKMSKSLGNIIDPDVVINGGQDHSKEPPYGADVLRWWVAESNVFTEVTISPSLLNAARDDISKLRNTLRFLLGNVAGFNPETDSIPVNSMYVIDQYMLHLLQDLANKINDSYKQYDFGKVVRLLQAFYTRELSNFYFSIIKDRLYCENADDPKRRSCQTALAEILDVMVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWIKTSSIWKKPGLEEAIESACAMRDSFLGSIPGKNAAEYEVIIVIEPGLLFEIMEMLQAEETSSTSQLNELMMASQTTLLSQEPRGISEDVTELKGTFLINLEGGDIREESSYKVIVMTTTKEKCPRCWKYTAESSDTLCPRCAEVVKGK", "length": 1012, "header": "tr|G3MWG4-1|G3MWG4_BOVIN Isoform 1 of Isoleucine--tRNA ligase, mitochondrial OS=Bos taurus OX=9913 GN=IARS2 PE=3 SV=2 CANONICAL=G3MWG4-1" }, "locus": { "chromosome": "16", "start_pos": 23630934, "end_pos": 23586996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061457.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061457.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053447.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053447.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K261-1", "protein_name": "Isoleucine--tRNA ligase, mitochondrial", "gene_name": "Iars2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLHPHGPGTAALTAAGSLWGPARFPSRLGCLGMTRRLVVRSVAGADSPQSSPKSGRYRDTVLLPQTNFPMKLLGHQQSDMELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIVNRFHMMRGSKVHFVPGWDCHGLPIETKVLSELGVNTQTLSAMEIREKARSFAQAAIEKQKSAFARWGVMADWSNCYYTFDPKYEAKQLRVFQQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSVYVRFPLLKPPPTLESLTGASSPVSALVWTTQPWTVPANQAICYMPEAKYAVVKCSASGNFYILAEDKISPVASALETTFDVTATFSGVDLEGGTCSHPLIPDKVSPLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSLPMDCLVDEEGMFTSAAGPELQNKAVLTEGTDVVIKMLQATKNLLKEESIVHSYPCDWRTKKPVLIRASKQWFVNIMDIKATAKESLKTVKFIPGAALNSMMDMLDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIIKLVEQHGSDVWWTLPAEKLLPEEVVAQAGGPGALEYVPGQDILDIWFDSGTSWSCVLQGTEQRADLYLEGKDQLGGWFQSSLLTSVATRSKAPFRTVMVHGFTLGEKGEKMSKSLGNVIDPDTIISGGKDHSKEPPYGADILRWWIAESNVFTEVTIGPSVLSAARDDISKLRNTLRFLLGNLAGFNPETASVPVKNMYIIDQYMLHLIQDFATKVTDSYKQYDFGKVVRLLKAFYTRELSSFYFSIVKDRLYCESETDPKRRSCQTALAEILDVLVRSFAPVLPHLAEEVFQHIPYVKEPKSVFRTGWISTSSVWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYDVIIVIEPGLLFEIMEMLQAEETSSTSQLNELMMASQTTLLAQEPRERSADAIELTGTFVINLEGQNLTRVRIVEGRRALGRSVQ", "length": 986 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A480QG80-1", "protein_name": "Isoleucine--tRNA ligase, mitochondrial", "gene_name": "IARS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRWGLRPSGPGAAALAAARNLWVQPRPSCRPSWRGTTGRLSVRSVTGASNQLQNSRNGSYRDTVLLPQTSFPMKLLGSQQPDTELEIQQKCGFSELYSWQRERKAKTEFCLHDGPPYANGDPHVGHALNKILKDIANRYHMMRGSKIHFVPGWDCHGLPIEIKVLSELGGKAQNLSAMEIREKARSFAKAAIEKQKSAFIRWGIMADWDNCYYTFDGKYEARQLRIFYQMYDKGLIYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSVYVKFPLLKPSPKLASLIDGSSPVSFLVWTTQPWTIPANQAVCYMPESKYAVVKCSKSGDFYILAADKVTSVASTLGTTFEVISTFSGVDLESGTCTHPLIAERASPLLPANHVTMTKGTGLVHTAPAHGMEDYSVASQHSLSTDCLVNEDGVFTDAAGPELQNKAVLEEGTEVVIKMLQAANNLLKEEELVHSYPYDWRTKKPVVIRASKQWFVNITDVKTTAKDLLKKVKFIPESALNAMVDMMDRRPYWCISRQRVWGVPIPVFHHKTKDEFLINSQTVEHIAKLVEEHGSDIWWTLPSEQLLPKEVLSQVGGPDALEYVPGRDILDIWFDSGTSWSYVLPGTDQRADLYLEGKDQLGGWFQSSLLTSVAARRKSPFKTVVVHGFTLGEKGEKMSKSLGNVIDPDVVINGGQDQSKEPPFGADVLRWWVAESNVFTEVTISPSVLRAARDDVSKLRNTLRFLLGNVAGFNPETDSVPVNDMYVIDQYMLHLLQDLANKVTDAYKQYDFGKVVRLLRAFYTRELSTFYFSIIKDRLYCENAKDPKRRSCQTALAEILDVLVRSFAPILPHLAEEVFQYVPYAKEPKSVFRTGWIKTSPIWKKPGLEEAIEGACAMRDSFLGSIPGKNAAEYEVILVIEPGLLFEIIEMLQAEETSSTSQLNELMMASQTTLLPREPRTLTPDVMERRGTFLINLEGGDIREESAYKVIVMPTTKEKCPRCWKHTAASADALCPRCADVVGGQ", "length": 1012 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QUQ0-1", "protein_name": "isoleucine--tRNA ligase", "gene_name": "iars2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLVRRSAAGFGGVVRWGLRCLCSGDAAGRYRNTVLLPRTDFPIKVNGPSLLEQEIKIQQKCGFDQLYKWQREKKAKKEYCLHDGPPYANGDPHVGHALNKILKDIRNRFEVLRGRQVHYVPGWDCHGLPIELKALGDLGTNELTPVQIRQKAREFAEKAISRQRAAFQRWGVMADWDNCYYTFDGKYEAAQLKVFQEMHNKGLIYQDYKPVFWSPSSRTALAEAELEYNPEHVSRSLYITFPLLTLPAKLTAKAEGLSNVSALIWTTQPWTIPANQAVCYMPKVQYSVVKRADTEQLLLVATERINSLSSLLKTNLESLVTFAGTDLEGGVCQHPTIPSKEVPLLPASHVTMTKGTGLVHTAPAHGMDDYSVATHFNLPVECMVDEEGRFTELAGAELQNKSVMDEGNAAVISVLQAAGAVVKEEDCVHSYPYDWRTKQPVVIRASRQWFINTATLKDKAKDALQKVRVIPESARSSLLSMLDRRTYWCISRQRSWGVPIPVFYHKETGEPLLNKHTVTHIAKVFSEKGSDSWWTEPVETFLTPDVLQKSKASSVSDYVRGEDVLDIWFDSGASWAAVLPESDPRADSYVEGKDQIGGWFQSSLLTSVAVRNKAPYKALVVHGFAVSEKGEKMSKSIGNVVDPDVVINGGKDSSVSPPYGADVLRWWVAESNVFSEVQIGPNALNAAKDSINKLRNTLKFLLGNLQGFDPRSQAVDPKQMHYIDQYMLHLLREFSMKVTDAYSEFNYGLVIRLLQSFTARELSNFYFSIIKDRLYCDPEDSVGRRSCQTVLEEILDGVSRSIAPVLPHLAEEVYLHAPGHDEGNTLFRSGWINTSPVWRKPGLEEAVEGACAIRDSFLSSIPGRNAAEFDLVISIEPGLFFELMESLQEEPTSTSSQLTELMMTSRTTLTSALPRDLPSDAITSTGSFLINLEGGMIREESSYSIAAMPTALSRCPRCRRYTSDEPDCLCPRCQTMMEKNGK", "length": 983 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54CE4-1", "protein_name": "Probable isoleucine--tRNA ligase, mitochondrial", "gene_name": "mileS", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISLNNSFFNKRVIVNSFNNYKRSFGTKSQNEESAIVDSNHSFAHTLNLPKTTFSMKANAATREPTLLKDPYKLYKWQLENNKGENWVFHDGPPYANGDLHMGHALNKILKDIVNRYKVLKGFKVNYIPGWDCHGLPIEQQAFKKLKKSSDMKASDIRKIAGDFARKEIEKQSKGFQEMGILGDWENPYKTLDYGYEVEQIQTFYDMFNKGYIYRGVKPVHWSPSSRTALADAELEYNNNHTSKSIFVKFNVKSLSNHILNNLPTTSDINKAEMVISAIIWTTTPWTIPANQAICVNSEMDYILVKPIESEQYRNEMFIISKERLESLTKSFNIGELKVILEFKGEQLKGTITKHPQYDRESPIITGDHVIEGSGTGLVHTAPGHGVEDFQICQQQYPDLKVLSPVNDLGCFTDEVGEKFVGLEVLGDGNEAVINDLETIGSLLHKEDYIHKYPYDWRTKKPIIIRTTLQWFVGLKNIQKTALQSIERVNMVPPSGSNRLSSMIGKRTDWCISRQRVWGCPIPVLYNCKTNEPLINDESINHIKELFGKFGSDCWFEMSTQQLLPPSLKDQHENFVKGTDTMDVWFDSGTSWRGVLVERGIIDKDTGRADIYLEGSDQHRGWFQSSLLTSVCVRDIEPYKNVVTHGFLLDESGIKMSKSIGNTIVPSTVIKGGPNKVQNPPYGVDLLRTWVASSDYSKDISIGPNILIKILDGIKKIRNTLRFMLASNFDFDPTIHAIPYEKLSSLDKYALHRVFKLQESVTRHYDQFQFQKVHTEIINFSIEISSFYFDVIKRHLYAESPNSHSRRSTQTVLFKMLDVINIALAPITVHTSEDVFLHQYQFKNNGKGLDKNLIENSVFAHGWDQLPSQYENELISNQFTNIIAIRDVVNRVLQSMRSQGIIGRSDETIMELTVTNEESSPFYDNLFAINSQLDDIFCVSNVLLKKFNTFEKDVEQQQQQQQQQQQQQPQQIEPNSKGEFIFNTIISNNSKQLGRIEVLLKISDKFKCPRCWRHTSIENDKVCKPCDSVLNSLK", "length": 1034 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5ZKA2-1", "protein_name": "Isoleucine--tRNA ligase, mitochondrial", "gene_name": "IARS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLGAWRAAPRLRLRARFGVASVWARSAASEANSRRPAEESRQDSQYRDTVLLPHSRFAAQLPGRLQPDTELETQQKSGFLELYSWQRQRKAKQEFCLHDGPPYANGDPHVGHALNKILKDITNRFHMMRGYKVHYVPGWDCHGLPIELKALSEVKGAENLSPVEIRQKAKEFAERAIEKQKAAFIRWGIMADWANCYRTFDPKYEANQLRVFHKMYDKGFIYQDYKPVFWSPSAKTALAEAELEYNEQHVSRSVYMKFPLLKSPPKLASVIDGSSPASVLVWTTQPWTVPANQAVCYMPDAEYSVVKCATTGEHLILAADRVESTAAVLDTQFEVISTCKGVDLADGSCAHPTIAGRVSPLLPANHVTMTKGTGLVHTAPAHGMEDYNVASHHQLPTECLVDESGHFTEAAGPELKNKNVLEEGNEAVIKMLQAAGSLLKEEKYVHSYPYDWRTKKPMIIRASKQWFVNTANVKATAQEALKKVKIIPTSAVNRMLEMLDRRTFWCISRQRCWGVPIPVFYQKDTGESLINSETIADVIKIVEQQGTDAWWTLPIEQLLSKEAVAKAGGHNVLDYVKGQDVLDIWFDSGTSWAHVLEGAEQRADVYLEGKDQLGGWFQSSLLTSVATRKKAPYKTLVVHGFTLGEKGEKMSKSIGNVVDPDVVINGGDDHTKDPPYGADVLRWWVAESNVFTEVLIGPVVLNAARDDINKLRNTLRFMLGNMAGFNPETDSIPPSEMYIVDQYMLHLLQDYGSKVTEAYKEYDYSKVVRLLQAFCSRNLSNFYFSIIKDRLYCEEEKDPKRRSCQTVLAEALDVVVRSFAPILPHLAEEVFQHLPYKKDSEGVFRTGWINASSGWKKPGIEEAIEGACAMRDSFLGSISGKNALEYEVIIVIEPGLLFELMEALQAEESSRVSQLNEIMMASQTTLLSEIPKETPADANIVKGNFLINLEGGDIREESSYQVIALPTTKAKCPRCRRYTSDSSSTPCPRCLKVIAGKGST", "length": 1000 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BIJ6-1", "protein_name": "Isoleucine--tRNA ligase, mitochondrial", "gene_name": "Iars2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHWGLCPRGPGAAAVAAAGSFWGPARLPSRLGCLGMTRRLVVRSVAGADSPQSSSKGGRYRDTVLLPQTSFPMKLLGRQQSDMELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMRGSKVHFVPGWDCHGLPIETKVLSELGVDAQSLSAMEIREKARSFAQAAIEKQKSAFVRWGVMADWNNCYYTFDPKYEAKQLRVFYQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSIYVRFPLLRPPPKLESLTDASSPVSVLVWTTQPWTIPANQAICYMPEAKYAVVKCSASGHLYILAEDKIAPVASALETTFDVVAAFSGVDLEGGTCSHPLTPDKVSPLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSLPMDCLVDEGGMFTDAAGPELQNKAVLKEGTDVVIKMLQATKNVLKEENIVHSYPCDWRTKTPVLIRASKQWFVNITDIKAAAKESLKTVKFIPGAALNSMTDMLDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIIKLVEQHGSDVWWTLPAEQLLPAEVLAQAGGPGALEYAPGQDILDIWFDSGTSWSCVLQDTQQRADLYLEGKDQLGGWFQSSLLTSVATRSKAPFRTVMVHGFTLGEKGEKMSKSLGNVINPDTIISGGKDHSKEPPYGADILRWWIAESNVFTEVTIGPSVLSAARDDISKLRNTLRFLLGNLTGFNPETDSVPVKNMYVIDQYMLHLIQDFATKITDSYKQYDFGKVVRLLKAFYTRELSSFYFSIVKDRLYCENEKDPKRRSCQTALAEILDVLVRAFAPILPHLAEEVFQHIPYVTEPKSVFRTGWINTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYEVIIVIEPGLLFEIMEMLQAEETSSTSQLNELMMASQTTLLAQEPRERTAGDIELTGTFVINLEGGDIREESSYKVIVVPTAREKCPRCWKHTSETADALCPRCAEVIGAK", "length": 1012 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RXK8-1", "protein_name": "Isoleucine--tRNA ligase, chloroplastic/mitochondrial", "gene_name": "OVA2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSFFKSFAGNPREAAAMAMVQSSSYRVLSGKSCSNLRRNTPLDSFLAKGRSSVKAFSFLYVSRFSTEPNNEFGHSSKRRSRGPVMAAKKASEGEKQEDGKYKQTVDLPKTGFGMRANSLTREPELQKLWEENQVFKRVSDNNNGGSFILHDGPPYANGDLHMGHALNKILKDIINRYKLLQNYKVQYVPGWDCHGLPIELKVLQSLDQEVRKELTPLKLRAKAAKFAKATVKTQMESFKRFGVWADWNNPYLTLDPEYEAAQIEVFGQMALKGYIYRGRKPVHWSPSSRTALAEAELEYPEGHISKSIYAIFKLVGGAKTSLLDEFIPNIYLAVWTTTPWTMPANAAVAVNAKLQYSVVEVQSFSEDESTVTSNKKKIPGKVLKNQQKLFVIVATDLVPALEAKWGVKLSISKTFLGSDLENCRYTHPIDNRDCPVVIGGDYITTESGTGLVHTAPGHGQEDYATGLKYGLPLVSPVDDEGKFTEEAGQFRGLSVLGEGNTAVVSYLDENMSLVMEESYAHKYPYDWRTKKPTIFRATEQWFASVEGFRTATMDAINNVKWVPHQAVNRISAMTSSRSDWCISRQRTWGVPIPAFYHVKTKEPLMNEETINHVKSIISQKGSDAWWYMSVEDLLPEKYRDKAADYEKGTDTMDVWFDSGSSWAGVLGKREGLSFPADVYLEGTDQHRGWFQSSLLTSIATQGKAPYSAVITHGFVLDEKGMKMSKSLGNVVDPRLVIEGGKNSKDAPAYGADVMRLWVSSVDYTGDVLIGPQILRQMSDIYRKLRGTLRYLLGNLHDWRVDNAVPYQDLPIIDQHALFQLENVVKNIQECYENYQFFKIFQIIQRFTIVDLSNFYFDIAKDRLYTGGTSSFTRRSCQTVLSTHLLSILRVIAPIVPHLAEDVWQNLPFEYRNEDGSAAEFVFELKWPTLNEQWLSFPAEDVLFWQRLLELRTEVNKVLELARNEKMIGSSLEAKVYLHTADAGMAAKLLEMSEAKNEADTLQRIFITSQVEVLSSMEKEMISSVQHTGEYVEGENKVWIGVSRAEGSKCERCWNYSGQVGSFSDHPTLCGRCFSVIVANPPEPAVAAVNSLA", "length": 1093 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NSE4-1", "protein_name": "Isoleucine--tRNA ligase, mitochondrial", "gene_name": "IARS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWGLRPRGPGAAALATARSLWGTPRLPCSPGWQGATKRLLVRSVSGASNHQPNSNSGRYRDTVLLPQTSFPMKLLGRQQPDTELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSRSIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAGPELQNKAVLEEGTDVVIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGTSWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHIPYIKEPKSVFRTGWISTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYKVITVIEPGLLFEIIEMLQSEETSSTSQLNELMMASESTLLAQEPREMTADVIELKGKFLINLEGGDIREESSYKVIVMPTTKEKCPRCWKYTAESSDTLCPRCAEVVSGK", "length": 1012 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUY4-1", "protein_name": "isoleucine--tRNA ligase", "gene_name": "IleRS-m", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRIFYFRVGNRLYSMKAAKKDAKKYTDTINLPKTKFPNRLTAAKREEQERLVLENKIAVSYAYQEQRLAEKGKPTFVLHDGPPYANGQLHMGHAVNKILKDITLRQRVAHGQRVNYIPGWDCHGLPIELKATSTAPGQSAQEIRQKSRAFAWEAIKSQKEEFSSWGILANWQKDNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWSPSSRTALAEAELEYDANHISPSVYVRFALNPSSFDVKDKQIYALVWTTTPWTLPSNQAICYNASLEYVIVRLSDRNQDELYLMASALMADFEANTQLKCEIVQHLSGELLSKLSYNHPIDKEQSNLPFFDASHVQDSKGTGLVHTAPAHGPEDFLVSLTQKIPVKCFVNEEGTYTKEAPDFLRGKSVLDQGNSLVLDRIAEDVVHSSKLEHSYPIDWRTKKPVIIRASEQWFINTEKLKTPAADALEQVEIYPRANAEASKKALLTQLQKRPYWCISRQRAWGVPIPVLYSRESGKVVLNSALIEHLCNLLRKEGSIDFWWVKSVEELVPEHLLRELHHEAKDLVKGTDILDIWFDSGSTWSAVLGKDKIADLYLEGYDQFTGWFQSSLLMSIAARECAPYKALFVHGFTVDEKGYKMSKSLGNVISPKQITKKYGTDALRWWVASHGTQHMSITVSDKLLQQAAENLCKIRGTMRYLKGVIGEKQSGEKLIRTSDKSYLNRYLLSQLVEFESEVEKLYQAYEYNRVVACVQNFIANQVSAVYVHLIKDRLYCGDDHELLAIRQTLTHCYQQLCKSLWPIVPFLVEESWSYYDTTGGAFHEQIVQTNPEWQDTKATEVINAAFDVKRLINQQAGDVNTWHLAVTIKGKERSQLDLLRELHSPLGESVSNSELCEILQVGSVTLLQSHNSDLDIALSKLQISLCPRCRRYGLEDEQKTCQRCSDVMEAKN", "length": 941 }, "evidence": [ { "id": "G3MWG4", "url": "https://omabrowser.org/oma/group/G3MWG4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" }, { "name": "isoleucine-tRNA ligase activity", "id": "GO:0004822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004822", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "isoleucyl-tRNA aminoacylation", "id": "GO:0006428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006428", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "G3MWG4", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11060", "name": "", "equation": "tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MWG4-1" ], "evidence": [ { "id": "11060", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11060" } ] }, { "id": "R-BTA-9838081", "name": "LONP1 degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "Q2KIE6-1", "P15690-1", "P20000-1", "Q32LG3-1", "P20004-1", "A0AAA9S896-1", "P00829-1", "Q5EAD4-1", "Q2TBR0-1", "F1MTT7-1", "Q148N0-1", "P11181-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q0NXR6-1", "Q29RZ0-1", "F1MXW5-1", "F1N338-1", "G3MWG4-1", "A0A140T871-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "O02691-1", "A0A3Q1LR42-1", "Q3ZCH0-1" ], "evidence": [ { "id": "R-BTA-9838081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838081" } ] }, { "id": "R-BTA-9838093", "name": "LONP1 binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "Q2KIE6-1", "P15690-1", "P20000-1", "Q32LG3-1", "P20004-1", "A0AAA9S896-1", "P00829-1", "Q5EAD4-1", "Q2TBR0-1", "F1MTT7-1", "Q148N0-1", "P11181-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q0NXR6-1", "Q29RZ0-1", "F1MXW5-1", "F1N338-1", "G3MWG4-1", "A0A140T871-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "O02691-1", "A0A3Q1LR42-1", "Q3ZCH0-1" ], "evidence": [ { "id": "R-BTA-9838093", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838093" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T871", "gene_name": "GLUD1", "activity": [ { "ec_number": "1.4.1.3", "activity": "L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+).", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] }, { "ec_number": "1.4.1.3", "activity": "", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] } ] }, { "uniprot_ac": "A0A3Q1LR42", "gene_name": "NADK2", "activity": [ { "ec_number": "2.7.1.23", "activity": "NAD(+) + ATP = ADP + NADP(+) + H(+).", "evidence": [ { "id": "A0A3Q1LR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR42" } ] }, { "ec_number": "2.7.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1LR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR42" } ] } ] }, { "uniprot_ac": "A0A3Q1LS03", "gene_name": "", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A3Q1LS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS03" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A3Q1LS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS03" } ] } ] }, { "uniprot_ac": "A0A3Q1LS67", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] } ] }, { "uniprot_ac": "A0A3Q1LYU1", "gene_name": "PDK1", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3Q1LYU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYU1" } ] } ] }, { "uniprot_ac": "A0AAA9S896", "gene_name": "LONP1", "activity": [ { "ec_number": "3.4.21.53", "activity": "Hydrolysis of proteins in presence of ATP.", "evidence": [ { "id": "A0AAA9S896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S896" } ] }, { "ec_number": "3.4.21.53", "activity": "", "evidence": [ { "id": "A0AAA9S896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S896" } ] } ] }, { "uniprot_ac": "F1MTT7", "gene_name": "ECI1", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "F1MTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTT7" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "F1MTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTT7" } ] } ] }, { "uniprot_ac": "F1MXW5", "gene_name": "OXSM", "activity": [ { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "F1MXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXW5" } ] }, { "ec_number": "2.3.1.41", "activity": "", "evidence": [ { "id": "F1MXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXW5" } ] } ] }, { "uniprot_ac": "F1N338", "gene_name": "HADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "F1N338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N338" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "F1N338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N338" } ] } ] }, { "uniprot_ac": "G3MWG4", "gene_name": "IARS2", "activity": [ { "ec_number": "6.1.1.5", "activity": "tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate.", "evidence": [ { "id": "G3MWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ] }, { "ec_number": "6.1.1.5", "activity": "", "evidence": [ { "id": "G3MWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ] } ] }, { "uniprot_ac": "G3MWN1", "gene_name": "ARG2", "activity": [ { "ec_number": "3.5.3.1", "activity": "L-arginine + H2O = urea + L-ornithine.", "evidence": [ { "id": "G3MWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWN1" } ] }, { "ec_number": "3.5.3.1", "activity": "", "evidence": [ { "id": "G3MWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWN1" } ] } ] }, { "uniprot_ac": "G3N0R5", "gene_name": "HSPD1", "activity": [ { "ec_number": "5.6.1.7", "activity": "ATP + H2O + an unfolded polypeptide = ADP + phosphate + a folded polypeptide.", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ] }, { "ec_number": "5.6.1.7", "activity": "", "evidence": [ { "id": "G3N0R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0R5" } ] } ] }, { "uniprot_ac": "O02691", "gene_name": "HSD17B10", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.239", "activity": "testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.178", "activity": "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methyl-3-oxobutanoyl-CoA + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.53", "activity": "androstan-3alpha,17beta-diol + NAD(+) = 17beta-hydroxyandrostanone + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.159", "activity": "cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H(+).", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "O02691", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O02691" } ] } ] }, { "uniprot_ac": "P00829", "gene_name": "ATP5F1B", "activity": [ { "ec_number": "7.1.2.2", "activity": "ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out).", "evidence": [ { "id": "P00829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00829" } ] }, { "ec_number": "7.1.2.2", "activity": "", "evidence": [ { "id": "P00829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00829" } ] } ] }, { "uniprot_ac": "P11181", "gene_name": "DBT", "activity": [ { "ec_number": "2.3.1.168", "activity": "(2S)-2-methylbutanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = N(6)-{(R)-S(8)-[(2S)-2-methylbutanoyl]dihydrolipoyl}-L-lysyl-[protein] + CoA.", "evidence": [ { "id": "P11181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11181" } ] }, { "ec_number": "2.3.1.168", "activity": "", "evidence": [ { "id": "P11181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11181" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "P11181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11181" } ] } ] }, { "uniprot_ac": "P11966", "gene_name": "PDHB", "activity": [ { "ec_number": "1.2.4.1", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "P11966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11966" } ] }, { "ec_number": "1.2.4.1", "activity": "", "evidence": [ { "id": "P11966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11966" } ] } ] }, { "uniprot_ac": "P15690", "gene_name": "NDUFS1", "activity": [ { "ec_number": "7.1.1.2", "activity": "a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out).", "evidence": [ { "id": "P15690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15690" } ] }, { "ec_number": "7.1.1.2", "activity": "", "evidence": [ { "id": "P15690", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15690" } ] } ] }, { "uniprot_ac": "P20000", "gene_name": "ALDH2", "activity": [ { "ec_number": "1.2.1.3", "activity": "acetaldehyde + NAD(+) + H2O = acetate + NADH + 2 H(+).", "evidence": [ { "id": "P20000", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20000" } ] }, { "ec_number": "1.2.1.3", "activity": "", "evidence": [ { "id": "P20000", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20000" } ] } ] }, { "uniprot_ac": "P20004", "gene_name": "ACO2", "activity": [ { "ec_number": "4.2.1.3", "activity": "citrate = D-threo-isocitrate.", "evidence": [ { "id": "P20004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20004" } ] }, { "ec_number": "4.2.1.3", "activity": "", "evidence": [ { "id": "P20004", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20004" } ] } ] }, { "uniprot_ac": "P22600", "gene_name": "FECH", "activity": [ { "ec_number": "4.98.1.1", "activity": "heme b + 2 H(+) = protoporphyrin IX + Fe(2+).", "evidence": [ { "id": "P22600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22600" } ] }, { "ec_number": "4.98.1.1", "activity": "", "evidence": [ { "id": "P22600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22600" } ] } ] }, { "uniprot_ac": "Q0NXR6", "gene_name": "ACAD8", "activity": [ { "ec_number": "1.3.8.5", "activity": "2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "Q0NXR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0NXR6" } ] }, { "ec_number": "1.3.8.5", "activity": "", "evidence": [ { "id": "Q0NXR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0NXR6" } ] } ] }, { "uniprot_ac": "Q148N0", "gene_name": "OGDH", "activity": [ { "ec_number": "1.2.4.2", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "Q148N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148N0" } ] }, { "ec_number": "1.2.4.2", "activity": "", "evidence": [ { "id": "Q148N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148N0" } ] } ] }, { "uniprot_ac": "Q29RK1", "gene_name": "CS", "activity": [ { "ec_number": "2.3.3.1", "activity": "oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+).", "evidence": [ { "id": "Q29RK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RK1" } ] }, { "ec_number": "2.3.3.1", "activity": "", "evidence": [ { "id": "Q29RK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RK1" } ] } ] }, { "uniprot_ac": "Q29RZ0", "gene_name": "ACAT1", "activity": [ { "ec_number": "2.3.1.9", "activity": "2 acetyl-CoA = acetoacetyl-CoA + CoA.", "evidence": [ { "id": "Q29RZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RZ0" } ] }, { "ec_number": "2.3.1.9", "activity": "", "evidence": [ { "id": "Q29RZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RZ0" } ] } ] }, { "uniprot_ac": "Q2KIE6", "gene_name": "HMGCS2", "activity": [ { "ec_number": "2.3.3.10", "activity": "acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).", "evidence": [ { "id": "Q2KIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIE6" } ] }, { "ec_number": "2.3.3.10", "activity": "", "evidence": [ { "id": "Q2KIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIE6" } ] } ] }, { "uniprot_ac": "Q2TBR0", "gene_name": "PCCB", "activity": [ { "ec_number": "6.4.1.3", "activity": "propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "Q2TBR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBR0" } ] }, { "ec_number": "6.4.1.3", "activity": "", "evidence": [ { "id": "Q2TBR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBR0" } ] } ] }, { "uniprot_ac": "Q32LG3", "gene_name": "MDH2", "activity": [ { "ec_number": "1.1.1.37", "activity": "(S)-malate + NAD(+) = oxaloacetate + NADH + H(+).", "evidence": [ { "id": "Q32LG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LG3" 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Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192748", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWL9-1", "url": "https://www.uniprot.org/uniprotkb/G3MWL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPGRWYAVHPAQAKASRERGRLQMVKKEEEDESYTSVPAARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLRELCRWWLRPDVLSKAQILELLVLEQFLSILPEELRTWVQLHHPESGGEAVALLEELQRDFDETPWRDPAPAQSPDVHWMGTGALRAAQIWPPASPLRSGSALGDHLQPPYEIGVRDFLAGQPDPPAAQVPALCSKEGCADNQVTAQPQGTMTFKDVEVTFSQDEWGLLDASQRNLYRDVMLENYGNMASVVGPFTKPALISWLEAREPWGLNVQGVQFKGNPGAAPAGDELHVKTDKFILKPEPLEEAVTLAMPSGCHGAATVSEGPGLRESIAQKSGLKERCGNPTQVRVKKEETNSSHGAGKDCEDSGRSNSLHLRHITYLRGPRRKQSLKHGYGKHFRGSSYHYDYKEYGKGLRRMMGGFSLHQRIHAGLKGKAKDAHGKDFSLSSHHQHGQNLHVVGTLYKCSDCGRTFSRSSHLVCHQRLHTQEKPFKCRACGKAFRWSSNRVRHEKIHTRLKPYKCSLCDKAFRRMSVYRLHQETHAKQKYLESTQDEEALTCVSDFDHHLRDQSGERLFDCSQCRKSFHCKSYILEHQRIHTQEKPYKCPKCRKTFRWRSNFTRHMRLHQEEKFYDLDKCREELRQTSNSSQPQSAPTMEKALVCQQCGKTFIRKKTLINHQRIHTGEKPYRCHECAEEFPHRSAYIVHKRQHATKRKPEDAPSFSHDRAFQVPQTSPTTEEPYKCSQCGKVFRNHSFLLIHQRVHTREKPYKCKECGKSFRWSSNLSRHQRTHSLGKLDEYSESEDALNLQSQVLTGAKPFQCQECGKNFTRKRSLLDHEGIHSGEKRYKCNLCGKSYDRNYRLVNHQRIHTKERPFKCQCCGKDFIGKHTLSIHQRKHIRAAQSENGVAGLSSCQETGVKLHELKSGQENPLEDDEKTCNQRSELPGLQDIPTRGKCHKCSTCGKTFSKSSQLISHKRFHTRERPFKCRVCGKTFRWSSNLARHMKNHIRD", "length": 1027, "header": "tr|G3MWL9-1|G3MWL9_BOVIN Isoform 1 of Zinc finger protein 445 OS=Bos taurus OX=9913 GN=ZNF445 PE=3 SV=2 CANONICAL=G3MWL9-1" }, "isoforms": [ { "isoform_ac": "G3MWL9-1", "url": "https://www.uniprot.org/uniprotkb/G3MWL9/entry", "sequence": { "sequence": "MPPGRWYAVHPAQAKASRERGRLQMVKKEEEDESYTSVPAARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLRELCRWWLRPDVLSKAQILELLVLEQFLSILPEELRTWVQLHHPESGGEAVALLEELQRDFDETPWRDPAPAQSPDVHWMGTGALRAAQIWPPASPLRSGSALGDHLQPPYEIGVRDFLAGQPDPPAAQVPALCSKEGCADNQVTAQPQGTMTFKDVEVTFSQDEWGLLDASQRNLYRDVMLENYGNMASVVGPFTKPALISWLEAREPWGLNVQGVQFKGNPGAAPAGDELHVKTDKFILKPEPLEEAVTLAMPSGCHGAATVSEGPGLRESIAQKSGLKERCGNPTQVRVKKEETNSSHGAGKDCEDSGRSNSLHLRHITYLRGPRRKQSLKHGYGKHFRGSSYHYDYKEYGKGLRRMMGGFSLHQRIHAGLKGKAKDAHGKDFSLSSHHQHGQNLHVVGTLYKCSDCGRTFSRSSHLVCHQRLHTQEKPFKCRACGKAFRWSSNRVRHEKIHTRLKPYKCSLCDKAFRRMSVYRLHQETHAKQKYLESTQDEEALTCVSDFDHHLRDQSGERLFDCSQCRKSFHCKSYILEHQRIHTQEKPYKCPKCRKTFRWRSNFTRHMRLHQEEKFYDLDKCREELRQTSNSSQPQSAPTMEKALVCQQCGKTFIRKKTLINHQRIHTGEKPYRCHECAEEFPHRSAYIVHKRQHATKRKPEDAPSFSHDRAFQVPQTSPTTEEPYKCSQCGKVFRNHSFLLIHQRVHTREKPYKCKECGKSFRWSSNLSRHQRTHSLGKLDEYSESEDALNLQSQVLTGAKPFQCQECGKNFTRKRSLLDHEGIHSGEKRYKCNLCGKSYDRNYRLVNHQRIHTKERPFKCQCCGKDFIGKHTLSIHQRKHIRAAQSENGVAGLSSCQETGVKLHELKSGQENPLEDDEKTCNQRSELPGLQDIPTRGKCHKCSTCGKTFSKSSQLISHKRFHTRERPFKCRVCGKTFRWSSNLARHMKNHIRD", "length": 1027, "header": "tr|G3MWL9-1|G3MWL9_BOVIN Isoform 1 of Zinc finger protein 445 OS=Bos taurus OX=9913 GN=ZNF445 PE=3 SV=2 CANONICAL=G3MWL9-1" }, "locus": { "chromosome": "22", "start_pos": 16337918, "end_pos": 16329362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065626.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065626.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053920.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053920.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540408", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540408", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAK3-1", "protein_name": "Zinc finger protein 445", "gene_name": "Zfp445", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPGRCYAARSVQMSREHGRLHMVKKEEEEDGCISVETARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLQELCRWWMRPDVLSKAQMLELLVLEQFLSILPGELRTWVQLHCPESGAEVVALLEELQRDLDGTSLKDSCLTQNPDVHWIGTGPLQAAQIWSPASHVGKSSALEDYLETPHGIGEVVLTHSPAVSMPDYFQIEESIEHQETLTFQDVEVTFSQEEWGCLNSAQRNLYRDVILENYGNVVSVVGSSPKPALISWLEARKPWGMNICTVQLKREPDAAPEGGKLQIEPSKFILKQEPSKYTETCVKPSGCPASKGTGLKESFEQKSRLQKSCGDSVQMKEMKKGTDISQKAGRKSEILRNSDILELKHVKCVSVSRKKLSFKHGYDRNFRKSSHHYNNKYGEGLRDTVEGFGVYQNTGLKENEKDRCGETLRKSSHSHLEYQRYYSQGSLFKCRVCEKAFKWRSNCIRHEKIHTGVKPYKCSSCEKAFQRLSTYRLHQKTHTKQKHESRKYNNALPCSLDVSHCLINQDEEKNFYCSQCGKHFSCRSYALEHQRIHTQEKPYNCIRCRKTFRWKSNFTRHMKLHGKEVRNQERCQEDFKQNYSQSQVISTIEKTFLCQSCGKTFTQKKSLIEHQRIHTGEKLYQCSGCGKTFASRSSYIIHMKQKRHAIKIKPESGSLPFSQDTAFAIPQSGHNTEEPNQCKYCGRAFHNRSFLLIHERIHTREKPYKCRECEKAFRWRSNLYRHERKHFLHKRRKYHESKETSNLQSKIFIDEKPFWCQECGKTFTRKRSLLDHKGIHSGERRFKCNLCEKSFDRNYRLVNHQRIHTTEQPFQSQWHDKDFAGTHAHSVDQRKHRTLQSEYSLQSDKPGLSYCQDVRVNIQELELSGKKPLDNPSHESSMSTAFQNVPTKKACHKCSTCGKTFRKHSHLISHKRCHTKERPFKCIVCGKTFGWSSNLTRHVKSHFRD", "length": 980 }, "evidence": [ { "id": "G3MWL9", "url": "https://omabrowser.org/oma/group/G3MWL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H966-1", "protein_name": "Zinc finger protein 445", "gene_name": "Znf445", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPPGRCYAAHSAQASREHLRTVKKEEEEDGYTLVRTPRPQTLNRPGQELFRQLFRQLRYHESSGPLETLRRLQELCRWWMRPDVLSKAQMMELLVLEQLLSILPAELRMWVQLHCPESGAEVVALLEELQRDHHGIPLKDPCLSQNPDVHWIGTGALQSAQIWSPRKNSSAPKDHLEPPHKIGVCNFLPGQDDSPTVSVPTHFQTEESTGYQEALTFQDVTVTFSKEEWGYLDSAQRKLYRDVMLENYGNVVSVVGSFPKPALISWLEARKPRAVNICKVQPKRDSDTAPEGGKPQIKSHKFILKQDPSEYTETISLPSVCPETIVSEGTGLKESSEQKNGPQKPCGSPIRVKGADISNKTEDSEGLGSSDALDAKHVQCVSVSKKKQPFKQGLDRRFRRRSHHYNRKCGLRDTVERFGVHQSIRMRLTESEDTDKKGFILSSHHQQEHSTHAMRVYRCPDCGKTFSKRSHLEDHQRCHFEHKLFKCRVCEKAFKWRSNCVRHEKIHTGVKPYKCNSCGKAFQRLSACRLHQETHTKKTSESSQYKEALTCSLDRNHLTNKDEEKQLNCRHCGKSFSCKSYVLEHQRIHTKEKPYKCTRCRKTFRWQSNFSRHKRSHLEQEFRKQEKCREESKQNSNQSQDCGKTFTKKKPLIERRRIRKRQKAYQCTECGETFTYRSACIIHMENHAMERNPASQSTVFHIPQSSHNAKEPYKCKYCGRMFRIRSFLLIHLRVHTREKPYQCKECGKAFRWSSNLSRHERKHSLQQQCDYHENRETSKLESKILTGQKKPFWCQECGKTFTRKRSLLDHKGIHSGEKRFKCNLCEKSFDRNYRLVNHQRIHATERPFQSRWRGKDLVGIHARSVDQRENSRIVQLERSLHSDNPGLSSCWNARLNAQELKLSGKKPHKGRENPSDKSSRFIALQKVPTKKGCHKCNICEKTFGKHSHLISHRRFHTRERPFKCKVCGKTFRWSSNLTRHMKNHVN", "length": 986 }, "evidence": [ { "id": "G3MWL9", "url": "https://omabrowser.org/oma/group/G3MWL9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P59923-1", "protein_name": "Zinc finger protein 445", "gene_name": "ZNF445", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPGRWHAAYPAQAQSSRERGRLQTVKKEEEDESYTPVQAARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLRELCRWWLRPDVLSKAQILELLVLEQFLSILPGELRVWVQLHNPESGEEAVALLEELQRDLDGTSWRDPGPAQSPDVHWMGTGALRSAQIWSLASPLRSSSALGDHLEPPYEIEARDFLAGQSDTPAAQMPALFPREGCPGDQVTPTRSLTAQLQETMTFKDVEVTFSQDEWGWLDSAQRNLYRDVMLENYRNMASLVGPFTKPALISWLEAREPWGLNMQAAQPKGNPVAAPTGDDLQSKTNKFILNQEPLEEAETLAVSSGCPATSVSEGIGLRESFQQKSRQKDQCENPIQVRVKKEETNFSHRTGKDSEVSGSNSLDLKHVTYLRVSGRKESLKHGCGKHFRMSSHHYDYKKYGKGLRHMIGGFSLHQRIHSGLKGNKKDVCGKDFSLSSHHQRGQSLHTVGVSFKCSDCGRTFSHSSHLAYHQRLHTQEKAFKCRVCGKAFRWSSNCARHEKIHTGVKPYKCDLCEKAFRRLSAYRLHRETHAKKKFLELNQYRAALTYSSGFDHHLGDQSGEKLFDCSQCRKSFHCKSYVLEHQRIHTQEKPYKCTKCRKTFRWRSNFTRHMRLHEEEKFYKQDECREGFRQSPDCSQPQGAPAVEKTFLCQQCGKTFTRKKTLVDHQRIHTGEKPYQCSDCGKDFAYRSAFIVHKKKHAMKRKPEGGPSFSQDTVFQVPQSSHSKEEPYKCSQCGKAFRNHSFLLIHQRVHTGEKPYKCRECGKAFRWSSNLYRHQRIHSLQKQYDCHESEKTPNVEPKILTGEKRFWCQECGKTFTRKRTLLDHKGIHSGEKRYKCNLCGKSYDRNYRLVNHQRIHSTERPFKCQWCGKEFIGRHTLSSHQRKHTRAAQAERSPPARSSSQDTKLRLQKLKPSEEMPLEDCKEACSQSSRLTGLQDISIGKKCHKCSICGKTFNKSSQLISHKRFHTRERPFKCSKCGKTFRWSSNLARHMKNHIRD", "length": 1031 }, "evidence": [ { "id": "G3MWL9", "url": "https://omabrowser.org/oma/group/G3MWL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R2V3-1", "protein_name": "Zinc finger protein 445", "gene_name": "Znf445", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPGRWHAARSAQVSREQGCLRMVKEEEEDGYISMQTARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLQELCRWWMRPDVLSKAQMLELLVLEQFLSILPGELRTWVQLHCPESGAEVVALLEELQRDLDGTPLKDPCLTQNPDVHWIGTSALQPAQIWSPASHLKNSSALEDHLETSHGIGICDVLAEQTDSPAVSVPDYFQLEEGIEYQEALTFQDVEVTFSQEEWGCLNSAQRNLYRDVILENYGNVVSVVGSSPKPALISWLEARKPWGVNICTVQLKRDADAAPEGGKLQIKPNKFILKQKPSEYIEACVKTSVSPETSVSEETGLKESFKQKSRLQTSCGDSIQMKEMKEGADISQRTGRESEVLRNNDILELKHVKCVSVSRKRLSFKHGYDRNFRKSSHHYNNKYGEGLRGTGEGFGVYQNTGLKENGKDRYGETSRKSWHAHPEHRQPSYSEEGLFQCRVCGKAFKWRSNRIRHEKIHTGVKPYQCSLCEKAFQRLSSYRLHQKTHSKQKRGSSKYKNALTCSLDVSHHLTDRDERKHLHCNQCGKNFSCKSYAIEHQRIHTQEKPYKCTRCRKTFRWKSNFSRHMKLHHKEVYKQEKRQEDFKQSYRQSQVISTVEKTFPCQNCGKTFTQKKSLIEHQRIHTGEKPYQCSGCGETFTYRSSYIIHMKRTQHAIKIKPEHGCLTFSQGAVFPIPRGSHNTEGSNKCKYCGKAFHNRSFLLIHERVHTREKPYQCRECEKAFRWSSNLYRHQRKHFLHKRYKYRESKETSNLQSKILIDQKPFWCQECGKTFTRKRSLLDHKGIHSGERRFKCNLCEKSFDRNYRLVNHQRIHTTEQPQWRDKDFVGIHARSVDQRKHSNTLQSEYGLHSDKPGLSYCQDVRLNIQELSGKLRKECDNPSDESSKSIAFQNVPTKKKACHKCSTCGKTFKKHSHLISHKRCHTKERPFKCIVCGKTFRWSSNLTRHMKNHVRN", "length": 986 }, "evidence": [ { "id": "G3MWL9", "url": "https://omabrowser.org/oma/group/G3MWL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" }, { "name": "double-stranded methylated DNA binding", "id": "GO:0010385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010385", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" }, { "name": "epigenetic programing of female pronucleus", "id": "GO:0044726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044726", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" }, { "name": "negative regulation of gene expression via chromosomal CpG island methylation", "id": "GO:0044027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044027", "evidence": [ { "database": "UniProtKB", "id": "G3MWL9", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 800, "end_pos": 802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWL9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1027, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWL9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWL9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MWL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 481, "end_pos": 508, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MWL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 228, "end_pos": 298, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MWL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWL9" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 137, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], 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"https://www.orthodb.org/?gene=G3MWQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MWQ9", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWQ9-1", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESLEEISEEESPKERHTSSTPSWKLTAKEILATKTQNYFAQTKRAENILIQIAFSIGLSSIWRFPYLCHLNGGGSFILVYFFMLLFFGVPLMYMEMIMGKCLRVDNIRVWKQLVPWLGGIGYASILVCILVSLYNSIIITWSLSYLSNSFRYPLPWDKCPLVRNINTVTHQYFWYHTTLNASNHIEEEVETLVLNLTLGIFTVWFLLFLIMMVGLKISMQVIFLPYIILLCFLIRCLFLEGATTSLRRMVTTEFSAWASLDLWRQAGGHVLYSLGLGMGTIILFSYKSGGDNYAQVASLVILVNLVTSLLTTSIIFIVLGFWTTTSGHACIKQSISKLMQLIDEGVLPQNAKPPKDILLLPTLDYIKWINSLPGHLRQKVIHLSPSCSIKVQKEMFMEGPGLALAAFSQVVSLFPGSSFWAILFFMALLIIGLSNLMRLLEGIVFPLQNSISIFRNYPRILSAIVCLGGFLGSLVFTSRAGSYIMYLFDDLLVPLTLIITVVFQNMALAWIYGAGRFREEMFSEMGRPLWPFSSFLWCYVTLPGLLALLTICLMQLYQGTHLYYTAWNTSGSQEVKHLYPRNSLGWVIFLSILTFLPIPVHPLHQWWSLQDYVAPDPFGKLMSKKTPMLSSMSSQRPKHHSVKSPERTSNASTRGLSMSLLRSLKPESGCLSQDSEKYEGSSWFSLPLVTSLSSSLTIRTNLVIGEGSKPRTFRSSLASCYASFLLGIEAFTRSRWVTGFHEIRNRES", "length": 749, "header": "tr|G3MWQ9-1|G3MWQ9_BOVIN Isoform 1 of Transporter OS=Bos taurus OX=9913 GN=LOC785907 PE=3 SV=3 CANONICAL=G3MWQ9-1" }, "isoforms": [ { "isoform_ac": "G3MWQ9-1", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9/entry", "sequence": { "sequence": "MESLEEISEEESPKERHTSSTPSWKLTAKEILATKTQNYFAQTKRAENILIQIAFSIGLSSIWRFPYLCHLNGGGSFILVYFFMLLFFGVPLMYMEMIMGKCLRVDNIRVWKQLVPWLGGIGYASILVCILVSLYNSIIITWSLSYLSNSFRYPLPWDKCPLVRNINTVTHQYFWYHTTLNASNHIEEEVETLVLNLTLGIFTVWFLLFLIMMVGLKISMQVIFLPYIILLCFLIRCLFLEGATTSLRRMVTTEFSAWASLDLWRQAGGHVLYSLGLGMGTIILFSYKSGGDNYAQVASLVILVNLVTSLLTTSIIFIVLGFWTTTSGHACIKQSISKLMQLIDEGVLPQNAKPPKDILLLPTLDYIKWINSLPGHLRQKVIHLSPSCSIKVQKEMFMEGPGLALAAFSQVVSLFPGSSFWAILFFMALLIIGLSNLMRLLEGIVFPLQNSISIFRNYPRILSAIVCLGGFLGSLVFTSRAGSYIMYLFDDLLVPLTLIITVVFQNMALAWIYGAGRFREEMFSEMGRPLWPFSSFLWCYVTLPGLLALLTICLMQLYQGTHLYYTAWNTSGSQEVKHLYPRNSLGWVIFLSILTFLPIPVHPLHQWWSLQDYVAPDPFGKLMSKKTPMLSSMSSQRPKHHSVKSPERTSNASTRGLSMSLLRSLKPESGCLSQDSEKYEGSSWFSLPLVTSLSSSLTIRTNLVIGEGSKPRTFRSSLASCYASFLLGIEAFTRSRWVTGFHEIRNRES", "length": 749, "header": "tr|G3MWQ9-1|G3MWQ9_BOVIN Isoform 1 of Transporter OS=Bos taurus OX=9913 GN=LOC785907 PE=3 SV=3 CANONICAL=G3MWQ9-1" }, "locus": { "chromosome": "18", "start_pos": 55731885, "end_pos": 55720246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063664.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063664.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053962.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053962.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GSD2-1", "protein_name": "Transporter", "gene_name": "Slc6a21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQSFEDFLELKNKPVEEVHTASKKSDNPTSVSRGFRTREVRVTKIPNHFQAKKTENILILVAFSIGLGSTWRFPYLCHQNGGGSFLLMYFILLLLLGIPLMYMEMVIGQWLRMDNIQAWKYLVPWLSGVGYSNILACVLVVLYNSALVSWSLFYLGQSFDYPLPWQNCPLVENLSMVGNTCLWSEPHQYFWYHTLLQASNQMEEGIEVLVLNVTLCLFATWIFLYVTMVTRIKISVLMMIFSILFSNVLLLCFFIRTLFLNGSVRASLWRLVTIELSILSSLDAWRQAGGHVLYSLGLGMGTIITFSTYQPRGENYIKWASFVAMVNLATSLLSSFVIFLVMGFWTTTSGTMCIKRSVSNLINLIANGVLPKAAWPPGDIIHKPPLEYLAWINQLPNNLKSQVIHQTLPCSILIQKEKIMEGPGLSYVAFSQAISLFPGSSFWAIIFFMSLAIMGLGTMLTLLEGIVLPLQKSISTFAKHPNLVQVLVCLGGFLGSLVFSSRPGSYVVFLFDDLLVPMVLIIIVVIQNLSLAWLYGIKRFRAEVFGQLGSLVWSPFTFLWSYVTLPTLLVLLTIYFLNLYYSGSPYYVSWNDSMSHEVKQPYKKIPLGWVTFLSVLALLPILVYPLQHWWYLDDPNICETLEKPLSSKKTVTVPNRVTQWPVHPMRKLTLRNQEKSKALFQSKSPPENFLHPQTLITKKDSENYSTFSLPDATLPSQVGFSTLAIHEVSKYTGHSESFLDSQNTGKK", "length": 748 }, "evidence": [ { "id": "G3MWQ9", "url": "https://omabrowser.org/oma/group/G3MWQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MWQ9", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G3MWQ9", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "G3MWQ9", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "G3MWQ9", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "G3MWQ9", "url": "https://www.uniprot.org/uniprotkb/G3MWQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWQ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 749, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWQ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWQ9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 651, "end_pos": 653 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MWS8-1", "uniprot_ac": "G3MWS8", "uniprot_id": "G3MWS8_BOVIN", "mass": { "chemical_mass": 25636.0, "monoisotopic_mass": 25636.0 }, "refseq": { "ac": "XP_024850927", "name": "Krueppel-like factor 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850927" }, "gene_names": [ { "name": "KLF16", "type": "recommended", "evidence": [ { "id": "G3MWS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWS8" } ] }, { "name": "KLF16", "type": "synonym", "evidence": [ { "id": "XP_024850927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850927" } ] } ], "protein_names": [ { "name": "Krueppel-like factor 14", "type": "recommended", "evidence": [ { "id": "G3MWS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWS8/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 16", "type": "synonym", "evidence": [ { "id": "XP_024850927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850927" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWS8", "url": "https://www.uniprot.org/uniprotkb/G3MWS8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLF16", "url": "https://www.uniprot.org/uniprotkb/G3MWS8", "locus": { "chromosome": "7", "start_pos": 44172868, "end_pos": 44182899, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038055", "url": "https://www.ensembl.org/id/ENSBTAG00000038055" } ] } } ], "crossref": [ { "id": "G3MWS8", "url": "https://alphafold.ebi.ac.uk/entry/G3MWS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038055", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038055", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21573", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21573", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519163", "url": "https://www.ncbi.nlm.nih.gov/gene/519163", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519163", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519163", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQGCIKV", "url": "https://omabrowser.org/oma/group/FQGCIKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MWS8", "url": "https://www.orthodb.org/?gene=G3MWS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024850927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MWS8", "url": "https://www.uniprot.org/uniprotkb/G3MWS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWS8-1", "url": "https://www.uniprot.org/uniprotkb/G3MWS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGPATGLDVRAPRREAAPPGPPGPPPPAPAVLGPGPGAAAAAPHLLAASILADLRGGPSAAPGGASPASSSSAASSPSSGRAPGAAPAAAKSHRCPFPGCAKAYYKSSHLKSHLRTHTGERPFACDWPGCDKKFARSDELARHHRTHTGEKRFPCPLCSKRFTRSDHLTKHARRHPGFRPELLRRQGTRSTSPSDSLPCSLAGSPAPSPVPSPAPVGL", "length": 252, "header": "tr|G3MWS8-1|G3MWS8_BOVIN Isoform 1 of Krueppel-like factor 14 OS=Bos taurus OX=9913 GN=KLF16 PE=3 SV=2 CANONICAL=G3MWS8-1" }, "isoforms": [ { "isoform_ac": "G3MWS8-1", "url": "https://www.uniprot.org/uniprotkb/G3MWS8/entry", "sequence": { "sequence": "MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGPATGLDVRAPRREAAPPGPPGPPPPAPAVLGPGPGAAAAAPHLLAASILADLRGGPSAAPGGASPASSSSAASSPSSGRAPGAAPAAAKSHRCPFPGCAKAYYKSSHLKSHLRTHTGERPFACDWPGCDKKFARSDELARHHRTHTGEKRFPCPLCSKRFTRSDHLTKHARRHPGFRPELLRRQGTRSTSPSDSLPCSLAGSPAPSPVPSPAPVGL", "length": 252, "header": "tr|G3MWS8-1|G3MWS8_BOVIN Isoform 1 of Krueppel-like factor 14 OS=Bos taurus OX=9913 GN=KLF16 PE=3 SV=2 CANONICAL=G3MWS8-1" }, "locus": { "chromosome": "7", "start_pos": 44182700, "end_pos": 44173872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064075.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064075.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053983.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053983.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519163", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519163", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A8E7A9-1", "protein_name": "Krueppel-like factor 14", "gene_name": "klf16", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFAYSDYLAAECLVSISSGPVLHRPTPVSGAAQAPPQGLPAGEPDGSSEDREVRETLRLDGANMMTVAEILTDLHGKFRPMSAYSESSNSSCGESGYTTLSDSTTPTPTMTPSATPVPGQSQQIWGGGGAPRSPTKRHPCTFDGCDRVYGKSSHLKAHIRTHTGERPFPCTWPECEKKFARSDELARHLRTHTGEKRFLCPLCDKRFMRSDHLIKHARRHPNFQPSMINRKGSAQGSISIQPAAASTAE", "length": 250 }, "evidence": [ { "id": "G3MWS8", "url": "https://omabrowser.org/oma/group/G3MWS8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B2GUY9-1", "protein_name": "KLF transcription factor 16", "gene_name": "Klf16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGPAAGLDVRATRREATPPGTPGAPPPPATAPGSGGATAAPHLLAASILADLRGGPGVATAANTAGGTSPVSSSSAASSPSSGRAPGAAKSHRCPFPGCAKAYYKSSHLKSHLRTHTGERPFACDWPGCDKKFARSDELARHHRTHTGEKRFPCPLCTKRFTRSDHLTKHARRHPGFRPELLRRPGARSASPSDSLPCSLAGSPTPSPVPSPAPAGL", "length": 251 }, "evidence": [ { "id": "G3MWS8", "url": "https://omabrowser.org/oma/group/G3MWS8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LC62-1", "protein_name": "Krueppel-like factor 14", "gene_name": "KLF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGSATGLDVRAPRREAAPPGPPGPPPPVPVVPGPGPGAAAAAAAPHLLAASILADLRGGPGAAAGGASPASSSSAASSPSSGRAPGAAPAAAKSHRCPFPGCAKAYYKSSHLKSHLRTHTGERPFACDWPGCDKKFARSDELARHHRTHTGEKRFPCPLCSKRFTRSDHLTKHARRHPGFRPELLRRPGTRSTSPSDSLPCSLAGSPAPSPVPSPASTVL", "length": 254 }, "evidence": [ { "id": "G3MWS8", "url": "https://omabrowser.org/oma/group/G3MWS8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P58334-1", "protein_name": "Krueppel-like factor 16", "gene_name": "Klf16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGPAAGLDVRATRREATPPGTPGAPPPPATAPGPGGATAAPHLLAASILADLRGGPVVATAASTAGGTSPVSSSSAASSPSSGRAPGAAKSHRCPFHGCAKAYYKSSHLKSHLRTHTGERPFACDWPGCDKKFARSDELARHHRTHTGEKRFPCPLCTKRFTRSDHLTKHARRHPGFRPELLRRPGARSVSPSDSLPCSLAGSPTPSPVPSPAPAGL", "length": 251 }, "evidence": [ { "id": "G3MWS8", "url": "https://omabrowser.org/oma/group/G3MWS8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXK1-1", "protein_name": "Krueppel-like factor 16", "gene_name": "KLF16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MWU7-1", "uniprot_ac": "G3MWU7", "uniprot_id": "G3MWU7_BOVIN", "mass": { "chemical_mass": 81393.0, "monoisotopic_mass": 81393.0 }, "refseq": {}, "gene_names": [ { "name": "TPRN", "type": "recommended", "evidence": [ { "id": "G3MWU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ] } ], "protein_names": [ { "name": "Taperin", "type": "synonym", "evidence": [ { "id": "G3MWU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWU7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TPRN", "url": "https://www.uniprot.org/uniprotkb/G3MWU7", "locus": { "chromosome": "11", "start_pos": 106213509, "end_pos": 106221256, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047715", "url": "https://www.ensembl.org/id/ENSBTAG00000047715" } ] } } ], "crossref": [ { "id": "G3MWU7", "url": "https://alphafold.ebi.ac.uk/entry/G3MWU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047715", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047715", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR025903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SKWQQNG", "url": "https://omabrowser.org/oma/group/SKWQQNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21685", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21685", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21685:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21685:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWU7-1", "url": "https://www.uniprot.org/uniprotkb/G3MWU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGPGVGPLREGRRRAAAAVPGERWLRRPLRSMAGLGRPGPAPRAAMPAWKREILERKRAKLAALGGGAAPVAGAGATETAGPATEPLVLAESLGPLRENPFMRLESERRHGARRGGGAGVAGPGARPAEQLLELYCCVPGVRTIRADNILIIESAPGFPPAPAPNPGLGPGGTARIRAAEVLVYEAPPPPGRVSRLLQKFDPPAAPRRRGSPERVRPTPPPSPGPAVPRVGERAACFQSDPERCGSGLGPRPRRSDFLHKTSNNSFTVHPRGLRHSAGTCPLPNGPGAPESRAGAAKGFEDSAPGPGEWKPKVESGEAPAHQSPSPGTPSATPAAAPALPTLSPSSATPSQRQWVSAATSANDSFEIRPAPKPDMGRIPAGDLQARALASLRVNSRNSFVVIPKRKTSGAPPGEGRRSVAPPEEEGWASQHPEPEAQLVPGVNGVFAGERSPSRIEEGGSPAPTTALVDPAVRWQRPPSPPPSPRAAAEAEPAQGFQTPGLAKNGREPGRPGLPITFIDEVDSEDEVPQEAKLPCSRVGAPPQYHPHPTRPGHLSELQRRGGNTFTVVPKRKPGAVQANGEARPREAEEEEPGRVSEPSAAAGTSLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPPESSLQEAEAEEEEEGDAEEDAEAYGPDGAAEKPLALFLPRATFVSSVGPESPRLPDGSSGLSSYTPKHSVAFSKWPEQVLERTPSAEEAPSKEVMLTPAGQNDLSDFRSEPALYF", "length": 774, "header": "tr|G3MWU7-1|G3MWU7_BOVIN Isoform 1 of Taperin OS=Bos taurus OX=9913 GN=TPRN PE=4 SV=1 CANONICAL=G3MWU7-1" }, "isoforms": [ { "isoform_ac": "G3MWU7-1", "url": "https://www.uniprot.org/uniprotkb/G3MWU7/entry", "sequence": { "sequence": "MGGGPGVGPLREGRRRAAAAVPGERWLRRPLRSMAGLGRPGPAPRAAMPAWKREILERKRAKLAALGGGAAPVAGAGATETAGPATEPLVLAESLGPLRENPFMRLESERRHGARRGGGAGVAGPGARPAEQLLELYCCVPGVRTIRADNILIIESAPGFPPAPAPNPGLGPGGTARIRAAEVLVYEAPPPPGRVSRLLQKFDPPAAPRRRGSPERVRPTPPPSPGPAVPRVGERAACFQSDPERCGSGLGPRPRRSDFLHKTSNNSFTVHPRGLRHSAGTCPLPNGPGAPESRAGAAKGFEDSAPGPGEWKPKVESGEAPAHQSPSPGTPSATPAAAPALPTLSPSSATPSQRQWVSAATSANDSFEIRPAPKPDMGRIPAGDLQARALASLRVNSRNSFVVIPKRKTSGAPPGEGRRSVAPPEEEGWASQHPEPEAQLVPGVNGVFAGERSPSRIEEGGSPAPTTALVDPAVRWQRPPSPPPSPRAAAEAEPAQGFQTPGLAKNGREPGRPGLPITFIDEVDSEDEVPQEAKLPCSRVGAPPQYHPHPTRPGHLSELQRRGGNTFTVVPKRKPGAVQANGEARPREAEEEEPGRVSEPSAAAGTSLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPPESSLQEAEAEEEEEGDAEEDAEAYGPDGAAEKPLALFLPRATFVSSVGPESPRLPDGSSGLSSYTPKHSVAFSKWPEQVLERTPSAEEAPSKEVMLTPAGQNDLSDFRSEPALYF", "length": 774, "header": "tr|G3MWU7-1|G3MWU7_BOVIN Isoform 1 of Taperin OS=Bos taurus OX=9913 GN=TPRN PE=4 SV=1 CANONICAL=G3MWU7-1" }, "locus": { "chromosome": "11", "start_pos": 106221057, "end_pos": 106213853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064376.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064376.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054003.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054003.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 220, "start_aa": "Thr", "end_pos": 220, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr220", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 330, "start_aa": "Thr", "end_pos": 330, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr330", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 334, "start_aa": "Thr", "end_pos": 334, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr334", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2AI08-1", "protein_name": "Taperin", "gene_name": "Tprn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGLGRLDPGPRTVMPAWKREILERRRAKLAALSGGQGSGAAPDGPNERLVLAESLGPLSQNPFMRLESERRRGTRPAQQLLELYCRVPGVRTIRADNILIIESAPGFPPAVPPAAGIRAAEVVVYEAPQPGRVSRLLEKFDSPAAPCRRGSPERFRPALPQLPVASASAATRTPTNRSLAPASPVRLSQPAPPISPVPVAQRAGQRSACCEPAHPDGTAGPGARRSDFLQKTGSNSFTVHPRGLPRSAVNRSLSNGPMTQESPTGPANGLSGSPPVPGKWKPKVESKEPSLHPPPSPGTPSATSVGPPAFPAPSPASATPSQRQWVSSATSANDSFEIRPSSKPDMETIPIGDLQARALANLRVNSRNSFVLIPKRKAPGNYPLAGRQFEEPKGEVGWASQSQGLGSQLVSTVDGAPALEKSPLAAEMQWAVRKGACPRPAISDTDKCVRWQRPASPPPFLPATAEAEPAEGLGVPGLAKNGQEPVRPGLPVTFIDEVDSEEEAFQEAKLPSSAVGVPSQYHLHPARPGHTSELLNRGSNTFTVVPKRKPGTLQEPHLSQTNGQSQQGAEEQDAESLSGPHTTLENTLKKRYPTVHEIEVIGGYLALQKSCLIKAGSSRKKMKISFNDKSLHTTFEYPSESSLAQEEAEEEEEEEGEEDGEEEEVGPDSEKPFTVFLPRATFVSSVGPESSSGLSSYTPKHSMAFSKWQEQTLVQTPTDVELPPKEVMLTPASQNDLSDFRSEPALYF", "length": 749 }, "evidence": [ { "id": "G3MWU7", "url": "https://omabrowser.org/oma/group/G3MWU7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4KMQ1-1", "protein_name": "Taperin", "gene_name": "TPRN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALGRPGSGPRAAVPAWKREILERKRAKLAALGGGAGPGAAEPEQRVLAESLGPLRENPFMLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYTPKHSVAFSKWQEQALEQAPREAEPPPVEAMLTPASQNDLSDFRSEPALYF", "length": 711 }, "evidence": [ { "id": "G3MWU7", "url": "https://omabrowser.org/oma/group/G3MWU7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5XHX2-1", "protein_name": "Taperin", "gene_name": "Tprn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGLGRLDPGPRTVMPAWKREILERRRAKLAALSGGPGSGAAPDGPNERLVLAESLGPLSQNPFMRLESERRRGARPAQQLLELYCRVPGVRTIRADNILIIESAPGFPPAVPPASSIRAAEVVVYEEPQPGRVSRLLEKFDSPAAPRRRGSPERFRPALPQLPVAPASAATRAPTNRSLAPAPPVLPSQPAPPISPVPVAQRAGQRSACCEPAHPDGTAGPGARRSDFLQKTGSNSFTVHPRGLPGSAVNRSLSNGPMTQESPAGPANGLSGSPPVPGKWKPKVESKEPSLHPPPSPGTPSATPVGPPAFLAPSPASATPSQRQWVSSATSANDSFEIRPSSKPDMETIPIGDLQARALANLRVNSRNSFVLIPKRKAPGNYPSAAGRQFEEPKGEVGWASQSQGLGSQLVSTVDGAPALEKSSLAAEMQWAVREGGCPRPAISDTDKSVRRQRPASPPPFLPATTEAEPAEGLGVPGLTKNGQEPVRPGLPVTFIDEVDSEEAAFQEAKLPSSAVGVPSQYHLHPSTPGHTSELLNRGSNTFTVVPKRKPGTLQEPHLSQTNGQFQQGAEEQDADSLSGPHTTLENALKKRYPTVNEIEVIGGYLALQKSCLIKAGSSRKKMKISFNDKSLHTTFEYPSESSLAQEEAEEEEEEEEEEEGEDGEEEEVGPDSEKSFTVLLPRATFVSSVGPESSSGLSSYTPKHSMAFSKWQEQTLVQAPTEVELPPKEVMLTPASQNDLSDFRSEPALYF", "length": 753 }, "evidence": [ { "id": "G3MWU7", "url": "https://omabrowser.org/oma/group/G3MWU7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "pmid": "" }, { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "pmid": "" }, { "name": "stereocilium base", "id": "GO:0120044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120044", "evidence": [ { "database": "UniProtKB", "id": "G3MWU7", "url": "https://www.uniprot.org/uniprotkb/G3MWU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": 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"pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "G3MWX5", "url": "https://www.uniprot.org/uniprotkb/G3MWX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWX5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 148, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWX5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWX5" } ], "lectin_list": [], 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"mass": { "chemical_mass": 34773.0, "monoisotopic_mass": 34773.0 }, "refseq": { "ac": "NP_001377405", "name": "olfactory receptor family 4 subfamily L member 1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377405" }, "gene_names": [ { "name": "OR4L1", "type": "recommended", "evidence": [ { "id": "G3MWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWY1" } ] }, { "name": "OR4L1", "type": "synonym", "evidence": [ { "id": "NP_001377405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377405" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWY1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4L1", "type": "synonym", "evidence": [ { "id": "NP_001377405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377405" } ] }, { "name": "olfactory receptor family 4 subfamily L member 1", "type": "synonym", "evidence": [ { "id": "NP_001377405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377405" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377405", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377405" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MWY1", "url": "https://www.uniprot.org/uniprotkb/G3MWY1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWY1", "url": "https://www.uniprot.org/uniprotkb/G3MWY1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4L1", "url": "https://www.uniprot.org/uniprotkb/G3MWY1", "locus": { "chromosome": "10", "start_pos": 27459902, "end_pos": 27458973, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000061052", "url": "https://www.ensembl.org/id/ENSBTAG00000061052" } ] } } ], "crossref": [ { "id": "G3MWY1", "url": "https://alphafold.ebi.ac.uk/entry/G3MWY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048863", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048863", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787134", "url": "https://www.ncbi.nlm.nih.gov/gene/787134", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:787134", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787134", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MQGAMRK", "url": "https://omabrowser.org/oma/group/MQGAMRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MWY1", "url": "https://www.orthodb.org/?gene=G3MWY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ 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"https://www.uniprot.org/uniprotkb/G3MWY1/entry", "sequence": { "sequence": "MDLKNGSVVTEFILQGFSAAWELQIVFFVTFSLIYGATVLGNALIMVTVTCSSTLHSPMYFLLGNLSFLDMCLSTVTTPKMIRDLLTEHKTISIWGCMAQMFFMHLFGGVEMTLLIAMAFDRYVAVCKPLHYRKIMNHRLLNRFVILSWTIGFTHTMSQMVLTVNLPFCGPHIIDNIFCDLPLVIKLACVETYTLELFVIADSGLLSLICFLLLLVSYTVILATVQRRSSGGLSKALSTLSAHITVVSLFFGPCIFIYAWPFKSFASNKVLAVFYTVITPLLNPIIYTLRNQKMQEAMKKLRFQNVSST", "length": 309, "header": "tr|G3MWY1-1|G3MWY1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4L1 PE=3 SV=1 CANONICAL=G3MWY1-1" }, "locus": { "chromosome": "10", "start_pos": 27459899, "end_pos": 27458973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065360.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065360.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054039.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054039.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:787134", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787134", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSI0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDYKNGSAVTEFILVGFSGDWQLQTFFFVTFTLIYGTTVVGNILIIVTVAATSTLHSPMYFLLGNLSFLDMCLSTVTTPKMITDLLAARKSISFQGCMAQMFFMHFFGGAEMTLLIVMAFDRYVAICKPLHYRIIMSHRLLNRCIILSWTIGFIHTMSQMALTVNLPFCGHNIINNIFCDLPLVIKLACIETYTLELFVIADSGLLSFICFILLLVSYTVILVIVKHKSPGSLSKALSTLSAHIIVVTLFFGPCIFIYAWPFGSFASNTTLAVFYTVITPLLNPIIYTLRNREMKKAMRKLWIQHVSCT", "length": 309 }, "evidence": [ { "id": "G3MWY1", "url": "https://omabrowser.org/oma/group/G3MWY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PZU2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDYENGSAVTEFILVGFSGNWQLQIFFFVTFTLIYGATVVGNILIIVTVAANSALHSPMYFLLGNLSFLDMCLSTVTTPKMISDLLAAHKSISFQGCMAQMFFMHFFGGAEMTLLIVMAFDRYVAICKPLHYRIIMSHKLLNRFIILSWTIGFIHTMSQMALTVNLPFCGHNIINNIFCDLPLVIKLACIETYTLELFVIADSGLLSFISFFLLLVSYTVILLIVKHKSPGSLSKALSTLSAHIIVVTLFFGPCIFIYAWPFGSFASNTTLAVFYTVITPLLNPIIYTLRNQEMKKAMRKLWIQQVSCT", "length": 309 }, "evidence": [ { "id": "G3MWY1", "url": "https://omabrowser.org/oma/group/G3MWY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1S930-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLKNGSVVTEFILVGFSVGWELQFVFLVTFSLIYGATVLGNVLIMVTVTFSSTLHSPMYFLLGNLSFLDMCLSTVTTPKMIRDLLTEHKVISMWGCMAQMFFMHCFGGAEMTLLIVMAFDRYVAICKPLHYRTIMSHKLLKGFVILSWTIGFIHTMSQMVLTVNLPFCGPHIIDNIFCDLPLVIKLACMDTYTLELFIIADSGLLSFICFLLLLVSYTVILVTVQQRSSGGLSKALSTLSAHITVVTLFFGPCIFIYAWPFSSFAGNKILAVFYTVITPLLNPIIYTLRNEKMQEAMRKLWFQNASSTQNF", "length": 312 }, "evidence": [ { "id": "G3MWY1", "url": "https://omabrowser.org/oma/group/G3MWY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8NH43-1", "protein_name": "Olfactory receptor 4L1", "gene_name": "OR4L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLKNGSLVTEFILLGFFGRWELQIFFFVTFSLIYGATVMGNILIMVTVTCRSTLHSPLYFLLGNLSFLDMCLSTATTPKMIIDLLTDHKTISVWGCVTQMFFMHFFGGAEMTLLIIMAFDRYVAICKPLHYRTIMSHKLLKGFAILSWIIGFLHSISQIVLTMNLPFCGHNVINNIFCDLPLVIKLACIETYTLELFVIADSGLLSFTCFILLLVSYIVILVSVPKKSSHGLSKALSTLSAHIIVVTLFFGPCIFIYVWPFSSLASNKTLAVFYTVITPLLNPSIYTLRNKKMQEAIRKLRFQYVSSAQNF", "length": 312 }, "evidence": [ { "id": "G3MWY1", "url": "https://omabrowser.org/oma/group/G3MWY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3MWY1", "url": "https://www.uniprot.org/uniprotkb/G3MWY1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MWY1", "url": "https://www.uniprot.org/uniprotkb/G3MWY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MWY1", "url": "https://www.uniprot.org/uniprotkb/G3MWY1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G3MWY1", "url": "https://www.uniprot.org/uniprotkb/G3MWY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWY1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWY1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"NP_001377004", "name": "olfactory receptor family 10 subfamily AA member 1C", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377004" }, "gene_names": [ { "name": "OR10AA1C", "type": "recommended", "evidence": [ { "id": "G3MWY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWY2" } ] }, { "name": "OR10AA1C", "type": "synonym", "evidence": [ { "id": "NP_001377004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377004" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MWY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWY2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6N2", "type": "synonym", "evidence": [ { "id": "NP_001377004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377004" } ] }, { "name": "olfactory receptor family 10 subfamily AA member 1C", "type": "synonym", "evidence": [ { "id": "NP_001377004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377004" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377004" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MWY2", "url": "https://www.uniprot.org/uniprotkb/G3MWY2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWY2", "url": "https://www.uniprot.org/uniprotkb/G3MWY2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10AA1C", "url": "https://www.uniprot.org/uniprotkb/G3MWY2", "locus": { "chromosome": "3", "start_pos": 10869736, "end_pos": 10868792, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000060961", "url": "https://www.ensembl.org/id/ENSBTAG00000060961" } ] } } ], "crossref": [ { "id": "G3MWY2", "url": "https://alphafold.ebi.ac.uk/entry/G3MWY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13954", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13954", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "526177", "url": "https://www.ncbi.nlm.nih.gov/gene/526177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526177", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526177", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WMTECYL", "url": "https://omabrowser.org/oma/group/WMTECYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MWY2", "url": "https://www.orthodb.org/?gene=G3MWY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242:SF410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242:SF410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377004", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MWY2", "url": "https://www.uniprot.org/uniprotkb/G3MWY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWY2-1", "url": "https://www.uniprot.org/uniprotkb/G3MWY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLVNHTWTQSFLLAGFTTTGALQPLAFLGTLCIYLLTLAGNLFIIVLVQADSRLSTPMYFFISALSFLELWYVSTTVPTLLHTLLHGRSPISPTVCFVQLYVFHSLGMTECYLLSVMALDRYLAICRPLHYHALMSRQVQLWLAGATWAAGFSAALVPARLTATLPFCLKEVAHYFCDLAPLMRLACVDTGWHAQVHIAVIGIINACNLVLILGLYGGILRAVLKLPSAASRAKAFSTCSSHITVVVLFFASAFIVYVGPPESLPEGTDKLLALVYTFLTPFLNPIIYTFRNKEVREAVRRVTQSIRAMMKRP", "length": 314, "header": "tr|G3MWY2-1|G3MWY2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR10AA1C PE=3 SV=1 CANONICAL=G3MWY2-1" }, "isoforms": [ { "isoform_ac": "G3MWY2-1", "url": "https://www.uniprot.org/uniprotkb/G3MWY2/entry", "sequence": { "sequence": "MDLVNHTWTQSFLLAGFTTTGALQPLAFLGTLCIYLLTLAGNLFIIVLVQADSRLSTPMYFFISALSFLELWYVSTTVPTLLHTLLHGRSPISPTVCFVQLYVFHSLGMTECYLLSVMALDRYLAICRPLHYHALMSRQVQLWLAGATWAAGFSAALVPARLTATLPFCLKEVAHYFCDLAPLMRLACVDTGWHAQVHIAVIGIINACNLVLILGLYGGILRAVLKLPSAASRAKAFSTCSSHITVVVLFFASAFIVYVGPPESLPEGTDKLLALVYTFLTPFLNPIIYTFRNKEVREAVRRVTQSIRAMMKRP", "length": 314, "header": "tr|G3MWY2-1|G3MWY2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR10AA1C PE=3 SV=1 CANONICAL=G3MWY2-1" }, "locus": { "chromosome": "3", "start_pos": 10869733, "end_pos": 10868792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065220.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065220.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054040.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054040.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:526177", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526177", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LXK2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100758837", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX42-1", "uniprot_ac": "G3MX42", "uniprot_id": "G3MX42_BOVIN", "mass": { "chemical_mass": 56766.0, "monoisotopic_mass": 56766.0 }, "refseq": { "ac": "XP_059736163", "name": "amphoterin-induced protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736163" }, "gene_names": [ { "name": "AMIGO3", "type": "recommended", "evidence": [ { "id": "G3MX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX42" } ] }, { "name": "AMIGO3", "type": "synonym", "evidence": [ { "id": "XP_059736163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736163" } ] } ], "protein_names": [ { "name": "Amphoterin-induced protein 3", "type": "recommended", "evidence": [ { "id": "G3MX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX42/entry#names_and_taxonomy" } ] }, { "name": "AMIGO-3", "type": "synonym", "evidence": [ { "id": "G3MX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX42/entry#names_and_taxonomy" } ] }, { "name": "Alivin-3", "type": "synonym", "evidence": [ { "id": "G3MX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX42/entry#names_and_taxonomy" } ] }, { "name": "amphoterin-induced protein 3", "type": "synonym", "evidence": [ { "id": "XP_059736163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736163" } ] } ], "function": [ { "annotation": "May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain.", "evidence": [ { "database": "UniProtKB", "id": "G3MX42", "url": "https://www.uniprot.org/uniprotkb/G3MX42#function" }, { "database": "UniProtKB", "id": "ARBA00057334", "url": "https://www.uniprot.org/uniprotkb/ARBA00057334#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX42", "url": "https://www.uniprot.org/uniprotkb/G3MX42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AMIGO3", "url": "https://www.uniprot.org/uniprotkb/G3MX42", "locus": { "chromosome": "22", "start_pos": 50493562, "end_pos": 50485185, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045547", "url": "https://www.ensembl.org/id/ENSBTAG00000045547" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045547", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045547", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "132343540", "url": "https://www.ncbi.nlm.nih.gov/gene/132343540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:132343540", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132343540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TPCRCPP", "url": "https://omabrowser.org/oma/group/TPCRCPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24368", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24368", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24368:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24368:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059736163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MX42", "url": "https://www.uniprot.org/uniprotkb/G3MX42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX42-1", "url": "https://www.uniprot.org/uniprotkb/G3MX42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLVLQSTLLCLLRVGLGTQDSDSFLPHAPHNCPHKCVCAADLLDCAGLGLREVPVTLPAAAADLDLSHNGLQRLPPGWLAPLSRLRALHLNHNELEALGRGVFTNASGLRLLDLSSNALRALGRHDLDGLGALETLLLFNNHLAHLDERAFHRLGTLSRLYLGCNKLSSFSFNHLHGLGAAHLRILDLSSNHIGRTPVPDLAALPAFLKNGLYLHDNPLPCDCRLYHLLRRWHQRGLSAVSDFAREYTCLAFKVPDSRVRFFAHSRVFENCSVALAQDLERPEEQLHVQVGQSLRLHCNTSAPALRVAWVSPQHELLVAPGSRNGSIAVLADGSLAIGSVQPWHEGVFVCLATGPRLHHNQTHEYNVSVSFPHPEPDAFNTGFTTLLGCAVGLTLVLLYLFAPPCPGCRRCCRRTCHCCRRCRRWPQTPSPLRELSAQSSVLSTTPPDAPSRKASVHKHVVFLEPGRRGLNGRVQLAVAEDFDLYNPSGLRLKAGSESTSPTASEGLVMTWAAHGPH", "length": 519, "header": "tr|G3MX42-1|G3MX42_BOVIN Isoform 1 of Amphoterin-induced protein 3 OS=Bos taurus OX=9913 GN=AMIGO3 PE=3 SV=2 CANONICAL=G3MX42-1" }, "isoforms": [ { "isoform_ac": "G3MX42-1", "url": "https://www.uniprot.org/uniprotkb/G3MX42/entry", "sequence": { "sequence": "MARLVLQSTLLCLLRVGLGTQDSDSFLPHAPHNCPHKCVCAADLLDCAGLGLREVPVTLPAAAADLDLSHNGLQRLPPGWLAPLSRLRALHLNHNELEALGRGVFTNASGLRLLDLSSNALRALGRHDLDGLGALETLLLFNNHLAHLDERAFHRLGTLSRLYLGCNKLSSFSFNHLHGLGAAHLRILDLSSNHIGRTPVPDLAALPAFLKNGLYLHDNPLPCDCRLYHLLRRWHQRGLSAVSDFAREYTCLAFKVPDSRVRFFAHSRVFENCSVALAQDLERPEEQLHVQVGQSLRLHCNTSAPALRVAWVSPQHELLVAPGSRNGSIAVLADGSLAIGSVQPWHEGVFVCLATGPRLHHNQTHEYNVSVSFPHPEPDAFNTGFTTLLGCAVGLTLVLLYLFAPPCPGCRRCCRRTCHCCRRCRRWPQTPSPLRELSAQSSVLSTTPPDAPSRKASVHKHVVFLEPGRRGLNGRVQLAVAEDFDLYNPSGLRLKAGSESTSPTASEGLVMTWAAHGPH", "length": 519, "header": "tr|G3MX42-1|G3MX42_BOVIN Isoform 1 of Amphoterin-induced protein 3 OS=Bos taurus OX=9913 GN=AMIGO3 PE=3 SV=2 CANONICAL=G3MX42-1" }, "locus": { "chromosome": "22", "start_pos": 50487386, "end_pos": 50485830, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093781.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093781.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089792.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089792.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:132343540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132343540", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HP20-1", "protein_name": "Amphoterin-induced protein 3", "gene_name": "Amigo3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGLVVPGILLCMLSAGSGTSDLEAALPPAPHDCPNNCICAADVLSCAGHGLQDVPVALPATAAELDLSHNALERLHPGWLAPLSRLRALYLGYNKLDVLGHGVFTNASGLRTLDLSSNMLRILHTHDLDGLGGLERLLLFNNKLVHLDPDAFQGLRMLRHLYLSCNELASFSFNGLHGLGTTHLRTLDLSSNWLGHISVSGLAALPAFLKNGLYLHNNPLPCDCRLYHLLQRWHQRGLSALRDFAREYTCLAFKVSESRVRFFEHSRVFENCSATAALGLELPEKQLDTQVGQSLRLYCNTSVPAARVAWVSPKNELLVAPGSQDGSIAVLADGSLAIGRVQEQHAGIFVCLATGPRLHHNQTLEFNVSVHKPRPEPEAFNTGFTTLLGCIVGLVLVLLYLFAPPCRGCCHCCRRACRNCCWPRAPSPLQELSAQSSVLSTTPPDAPSRKASVHKHVVFLEPGKKGLNGRVQLAVAEDFDLSNPMELQFKVGSESASSTGSEGLMMT", "length": 508 }, "evidence": [ { "id": "G3MX42", "url": "https://omabrowser.org/oma/group/G3MX42/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AI19-1", "protein_name": "Adhesion molecule with Ig like domain 3", "gene_name": "AMIGO3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPWAPAELWLLLLLLLQLCPARASAPRSCPPACICTSDLLSCSRQTLQRVPRALPPTATTLDLSHNALSQLQDGWLAALPHLEALHVGHNQIGELSPRAFHNASRLRHLDMSSNRLRAVERHYFEELVSLEELLLYNNHIARVDENAFARLSGLRKVYLSWNNLTSFPFHAVQGLGNFSLRTLDLSSNSLLSLPVEELAALPEHVRNGLYLHNNPVRCSCPLYLMLQRWRQRGFSSVRDFFEEHTCKVSDAVPRSLIKLLKYSHLFENCSAEPDPAQPVPFPVTVGRALLLACNASLPHAAYMWISPHHEPIRPPGNANRSVEVFHNGSLRIASARPWHSGVYVCLAISGPHNISRLCEVNVTVHYSKPDGEAFSTGLTTLLGCIVSLLLVLVYLFVTPCRCPPCCRTAPPSPPQECSAQSSILSATPPATDGPSRRASKHVAFLEPAREALDAKERPAPGEALPDGRHPKVLQLRSDTESISSVFSDTPIVS", "length": 494 }, "evidence": [ { "id": "G3MX42", "url": "https://omabrowser.org/oma/group/G3MX42/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q80ZD5-1", "protein_name": "Amphoterin-induced protein 3", "gene_name": "Amigo3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWLVLLGLLLCMLGAGSGTSDLEGVLPPDPHNCPNKCVCAADVLSCAGRGLQDLPAALPATAAELDLSHNALKRLHPGWLAPLSRLRALYLGYNKLDVLGRGVFTNASGLRILDLSSNLLRRLRTYDLDGLEELEKLLLFNNRLMHLDLDAFQGLSMLSHLYLSCNELSSFSFNHLHGLGLTRLRTLDLSSNWLGHVSVPELAALPTFLKNRLYLHNNPLPCDCSLYHLLRRWHQRGLSALHDFEREYTCLAFKVAESRVRFFEHSRVFKNCSVAAAPGLELPEEELHTHVGQSLRLFCNTTVPAARVAWVSPKNELLVAPGSQDGSIAVLADGSLAIGRVQEQHAGLFVCLASGPRLHHNQTLEYNVSVHKPRPEPEAFNTGFTTLLGCIVGLVLVLLYLFAPPCRGCCRCCRRACRNRCWPRASSPLQELSAQSSVLSTTPPDAPSRKASVHKHVAFLEPGKKGLNGRVQLAVAEDFDLCNPMGLQLKAGSESASSTGSEGLMMS", "length": 508 }, "evidence": [ { "id": "G3MX42", "url": "https://omabrowser.org/oma/group/G3MX42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86WK7-1", "protein_name": "Amphoterin-induced protein 3", "gene_name": "AMIGO3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTWLVLLGTLLCMLRVGLGTPDSEGFPPRALHNCPYKCICAADLLSCTGLGLQDVPAELPAATADLDLSHNALQRLRPGWLAPLFQLRALHLDHNELDALGRGVFVNASGLRLLDLSSNTLRALGRHDLDGLGALEKLLLFNNRLVHLDEHAFHGLRALSHLYLGCNELASFSFDHLHGLSATHLLTLDLSSNRLGHISVPELAALPAFLKNGLYLHNNPLPCDCRLYHLLQRWHQRGLSAVRDFAREYVCLAFKVPASRVRFFQHSRVFENCSSAPALGLERPEEHLYALVGRSLRLYCNTSVPAMRIAWVSPQQELLRAPGSRDGSIAVLADGSLAIGNVQEQHAGLFVCLATGPRLHHNQTHEYNVSVHFPRPEPEAFNTGFTTLLGCAVGLVLVLLYLFAPPCRCCRRACRCRRWPQTPSPLQELSAQSSVLSTTPPDAPSRKASVHKHVVFLEPGRRGLNGRVQLAVAEEFDLYNPGGLQLKAGSESASSIGSEGPMTT", "length": 504 }, "evidence": [ { "id": "G3MX42", "url": "https://omabrowser.org/oma/group/G3MX42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C2S7-1", "protein_name": "Amphoterin-induced protein 3", "gene_name": "Amigo3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWLVLSGILLCMLGAGLGTSDLEDVLPPAPHNCPDICICAADVLSCAGRGLQDLPVALPTTAAELDLSHNALKRLHPGWLAPLSRLRALHLGYNKLEVLGHGAFTNASGLRTLDLSSNMLRMLHTHDLDGLEELEKLLLFNNSLMHLDLDAFQGLRMLSHLYLSCNELSSFSFNHLHGLGLTRLRTLDLSSNWLKHISIPELAALPTYLKNRLYLHNNPLPCDCSLYHLLRRWHQRGLSALHDFEREYTCLVFKVSESRVRFFEHSRVFKNCSVAAAPGLELPEEQLHAQVGQSLRLFCNTSVPATRVAWVSPKNELLVAPASQDGSIAVLADGSLAIGRVQEQHAGVFVCLASGPRLHHNQTLEYNVSVQKARPEPETFNTGFTTLLGCIVGLVLVLLYLFAPPCRGCCHCCQRACRNRCWPRASSPLQELSAQSSMLSTTPPDAPSRKASVHKHVVFLEPGKKGLNGRVQLAVAEDFDLCNPMGLQLKAGSESASSTGSEGLVMS", "length": 508 }, "evidence": [ { "id": "G3MX42", "url": "https://omabrowser.org/oma/group/G3MX42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MX42", "url": "https://www.uniprot.org/uniprotkb/G3MX42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "G3MX42", "url": "https://www.uniprot.org/uniprotkb/G3MX42" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "G3MX42", "url": "https://www.uniprot.org/uniprotkb/G3MX42" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "G3MX42", "url": "https://www.uniprot.org/uniprotkb/G3MX42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX52-1", "uniprot_ac": "G3MX52", "uniprot_id": "G3MX52_BOVIN", "mass": { "chemical_mass": 42977.0, "monoisotopic_mass": 42977.0 }, "refseq": { "ac": "XP_002692744", "name": "XK-related protein 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692744" }, "gene_names": [ { "name": "XKR9", "type": "recommended", "evidence": [ { "id": "G3MX52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX52" } ] }, { "name": "XKR9", "type": "synonym", "evidence": [ { "id": "XP_002692744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692744" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "G3MX52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX52/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002692744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692744" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX52", "url": "https://www.uniprot.org/uniprotkb/G3MX52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "XKR9", "url": "https://www.uniprot.org/uniprotkb/G3MX52", "locus": { "chromosome": "14", "start_pos": 34390632, "end_pos": 34370067, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048138", "url": "https://www.ensembl.org/id/ENSBTAG00000048138" } ] } } ], "crossref": [ { "id": "G3MX52", "url": "https://alphafold.ebi.ac.uk/entry/G3MX52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048138", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048138", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100300765", "url": "https://www.ncbi.nlm.nih.gov/gene/100300765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100300765", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDCRMKY", "url": "https://omabrowser.org/oma/group/RDCRMKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MX52", "url": "https://www.orthodb.org/?gene=G3MX52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002692744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692744", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MX52", "url": "https://www.uniprot.org/uniprotkb/G3MX52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX52-1", "url": "https://www.uniprot.org/uniprotkb/G3MX52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKYTKFNFMMSVLGIMIYVTDLIVDIWVSVRFFHERQYVFGVLTVSFMLFGTLVVQCFSYSWFKADLKEAGQESHHCFLLLHCLQGGVFTRYWFALKQGYQVAFKYSSKTENFVEKQINDRVTDLSMLRLFETYLEGCPQLALQLYIFLEHGQANFTQYAAIMVSCCAVSWSTVDYQIALRKSLPDKNLLNGPCPKLVYLFYKLFTLLSWMLSVVLLLFLNVKIAFLLLFFLWILGIYWAFKKQTDFCVSTSMEILYRIVVGFILTFTFFNIKGQNTKCPMSCYYIVRVLVTLGILIVFWFYPLSIFNADYFIPVSITIVLSLLLGIIFLLVYYGTLHPNRSEETKLDEVDGKPIQRDCRMKHFLME", "length": 367, "header": "tr|G3MX52-1|G3MX52_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR9 PE=3 SV=1 CANONICAL=G3MX52-1" }, "isoforms": [ { "isoform_ac": "G3MX52-1", "url": "https://www.uniprot.org/uniprotkb/G3MX52/entry", "sequence": { "sequence": "MKYTKFNFMMSVLGIMIYVTDLIVDIWVSVRFFHERQYVFGVLTVSFMLFGTLVVQCFSYSWFKADLKEAGQESHHCFLLLHCLQGGVFTRYWFALKQGYQVAFKYSSKTENFVEKQINDRVTDLSMLRLFETYLEGCPQLALQLYIFLEHGQANFTQYAAIMVSCCAVSWSTVDYQIALRKSLPDKNLLNGPCPKLVYLFYKLFTLLSWMLSVVLLLFLNVKIAFLLLFFLWILGIYWAFKKQTDFCVSTSMEILYRIVVGFILTFTFFNIKGQNTKCPMSCYYIVRVLVTLGILIVFWFYPLSIFNADYFIPVSITIVLSLLLGIIFLLVYYGTLHPNRSEETKLDEVDGKPIQRDCRMKHFLME", "length": 367, "header": "tr|G3MX52-1|G3MX52_BOVIN Isoform 1 of XK-related protein OS=Bos taurus OX=9913 GN=XKR9 PE=3 SV=1 CANONICAL=G3MX52-1" }, "locus": { "chromosome": "14", "start_pos": 34390419, "end_pos": 34370266, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065088.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065088.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054112.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054112.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100300765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300765", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MA31-1", "protein_name": "XK-related protein", "gene_name": "Xkr9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKYTKCNFAMSVLGIIIYVTDLVADIFLSVRYFHNGQYVFGVLTLSFVLCGTLIVQCFSYSWLKDDLKKTGQENEHYFLLLHCFQGGVFTRYWFALRKGYDVVFKHSKRTSNFMEEKPDPHREAIDIATDLSMLRLFETYLEGCPQLILQLYAFLERGQANLSQYAVILISCCAISWSTVDYQVALRKSLPDKNLLRGVCPKLTYLFYKLFTLLSWTLSIVLLLFVDVKVALFLLLFLWIIGFIWAFIKQTKFCNSLSMEFLYRAVVGVILVFTFFNIKGQDTKCPMSCYYTVRVLGTLGILTVFWAYPLSIFNSEYFIPISAIVILALLLGIVFLTVYYGVFHPNRNIEAQHDETDGKSVQRDCRMRYFLMD", "length": 373 }, "evidence": [ { "id": "G3MX52", "url": "https://omabrowser.org/oma/group/G3MX52/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XEX7-1", "protein_name": "XK-related protein", "gene_name": "XKR9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMKFTKWNFIFLLGGIIVYIADIGVDFWVASKYFYQGQYFWAVLILCFRGLSSLVTQIFSYHWFKNDWNGTHPGKLDWIFLVHFFHCGIFIRYWFALKYGCQAAFRQDSSGDVSETDPPNIIQKQAIDVLTDINMLRVFKTFLETTPQLFVQIYVLMEYNNHNFYQYAAIIISFCGISFSMVDYQISLRKSLPDKEELEALPKLVYLFYKLLTITSWILSISLITLLSVRSSVIVLILLWSCGFAWTLKQHTTFCKSKEMEYLYRTVVGIILLFTFFNIKGRKTKAYISIYYATHTIVTVGILLVCLFWKPAVIEKVHLTIVSGLAVISLVLGLIFLAVYYKYFHPTTYCKQRTFFDEVDRRGGDNMEVGRFQNFIMQ", "length": 378 }, "evidence": [ { "id": "G3MX52", "url": "https://omabrowser.org/oma/group/G3MX52/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RU13-1", "protein_name": "XK-related protein", "gene_name": "XKR9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKYTKLDFVTSVLGIIIYIIDLIVDIWVSIRFFHEGQYVPGVLTVSFVLFGTLVVQCFSYSWFKADLKKAGQEIQHCFLLLHCLQGGVFTRYWFALKRGYYVAFKYSSKTDNFVEEQIDPHKEVIDRVTDLSMLRLFDTYLEGCPQLALQLYTLLENGQANYTQYAAIMVSCCAISCSTVDYQIALRKSLPDKNPLKGPWPKLIYLFYKLFTLSSWMLSIVLLLFLNVKVALFLLLLLWFLGILWAFKEQTDFCASRSMEFIYRIVVGFILTFTFFNIKGQNTKCPMSCYYTVRVLTTLGIVIVFWFCPLSIFNSHYFIPISITIALTLLLGIIFLIVYYGTLHPNKSKETTLDEIDGKPVQRDCRMKYFLME", "length": 373 }, "evidence": [ { "id": "G3MX52", "url": "https://omabrowser.org/oma/group/G3MX52/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9PHA4-1", "protein_name": "XK-related protein", "gene_name": "Xkr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASAEQRTEVDALMMGPISKLSMLLTVVSILWRFVSICINWSLAYVYWMEESYGYCAWTIGSILVPMVVTSVIYIHTLKSAHAGEKRILERGVYSNAVISYLFRDVYVLNYAFKYSLAKERDDKQAEIEYYQKLMTEECNVSFVRLFDSFLESAPQKILQLAILLQSTLEFTYYRHIALIVYFGNIAWCIQAYNHSNRLAQLDKHDIAAKGRFLQFLFLLCLTVIRFYFVVSRTLCIAYVASIFPIETLIICATLACFYGTIVFFVDSPMIAKSRPMNYSYCLCFGVVYLFIFTPVKDAPTKYKYAFYLTFCLLQNIIACALYIPLYLATAIIALYIVGIVLLIIYYTYCHPNTVRTYF", "length": 359 }, "evidence": [ { "id": "G3MX52", "url": "https://omabrowser.org/oma/group/G3MX52/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5GH54-1", "protein_name": "XK-related protein 9", "gene_name": "Xkr9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKYTICNFMMSVLGIIIYVTDLVADIVLTVRYFYDGQYVFGVLTLSFVLCGTLIVHCFSYSWLKDDLKKAGGENEHYFLLLHCLQGGVFTRYWFVLRTGYHVVFKHSHRTSNFMEEQTDPHKEAIDMATDLSMLRLFETYLEGCPQLILQLYAFLERGQANFSQYMVIMVSCCAISWSTVDYQIALRKSLPDKNLLRGFWPKLTYLFYKLFTLLSWMLSVVLLLFVDVRTVLLLLLFLWTVGFIWAFINHTQFCNSLSMEFLYRLVVGFILVFTFFNIKGQNTKCPMSCYYTVRVLGTLGILTVFWIYPLSIFNSDYFIPISATIVLSLLFGIIFLGVYYGTYHPNINAGTQHDEPDGKAPQRDCRIRYFLMD", "length": 373 }, "evidence": [ { "id": "G3MX52", "url": "https://omabrowser.org/oma/group/G3MX52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GH62-1", "protein_name": "XK-related protein 9", "gene_name": "Xkr9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYTKCNFMMSVLGIIIYVTDLVADIVLSVRYFHDGQYVLGVLTLSFVLCGTLIVHCFSYSWLKADLEKAGQENERYFLLLHCLQGGVFTRYWFALRTGYHVVFKHSDRKSNFMEEQTDPHKEAIDMATDLSMLRLFETYLEGCPQLILQLYAFLECGQANLSQCMVIMVSCCAISWSTVDYQIALRKSLPDKNLLRGLWPKLMYLFYKLLTLLSWMLSVVLLLFVDVRVALLLLLFLWITGFIWAFINHTQFCNSVSMEFLYRIVVGFILVFTFFNIKGQNTKCPMSCYYTVRVLGTLGILTVFWIYPLSIFNSDYFIPISATIVLALLLGIIFLGVYYGNFHPNRNVEPQLDETDGKAPQRDCRIRYFLMD", "length": 373 }, "evidence": [ { "id": "G3MX52", "url": "https://omabrowser.org/oma/group/G3MX52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5GH70-1", "protein_name": "XK-related protein 9", "gene_name": "XKR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKYTKQNFMMSVLGIIIYVTDLIVDIWVSVRFFHEGQYVFSALALSFMLFGTLVAQCFSYSWFKADLKKAGQESQHCFLLLHCLQGGVFTRYWFALKRGYHAAFKYDSNTSNFVEEQIDLHKEVIDRVTDLSMLRLFETYLEGCPQLILQLYILLEHGQANFSQYAAIMVSCCAISWSTVDYQVALRKSLPDKKLLNGLCPKITYLFYKLFTLLSWMLSVVLLLFLNVKIALFLLLFLWLLGIIWAFKNNTQFCTCISMEFLYRIVVGFILIFTFFNIKGQNTKCPMSCYYIVRVLGTLGILTVFWVCPLTIFNPDYFIPISITIVLTLLLGILFLIVYYGSFHPNRSAETKCDEIDGKPVLRECRMRYFLME", "length": 373 }, "evidence": [ { "id": "G3MX52", "url": "https://omabrowser.org/oma/group/G3MX52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MX52", "url": "https://www.uniprot.org/uniprotkb/G3MX52" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MX52", "url": "https://www.uniprot.org/uniprotkb/G3MX52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MX52-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 367, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MX52-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MX52" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 340, "end_pos": 342 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX55-1", "uniprot_ac": "G3MX55", "uniprot_id": "G3MX55_BOVIN", "mass": { "chemical_mass": 48070.0, "monoisotopic_mass": 48070.0 }, "refseq": { "ac": "NP_001422099", "name": "forkhead box protein D2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422099" }, "gene_names": [ { "name": "FOXD2", "type": "recommended", "evidence": [ { "id": "G3MX55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ] }, { "name": "FOXD2", "type": "synonym", "evidence": [ { "id": "NP_001422099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422099" } ] } ], "protein_names": [ { "name": "Forkhead box protein L2", "type": "recommended", "evidence": [ { "id": "G3MX55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX55/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein D2", "type": "synonym", "evidence": [ { "id": "NP_001422099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422099" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FOXD2", "url": "https://www.uniprot.org/uniprotkb/G3MX55", "locus": { "chromosome": "3", "start_pos": 98832725, "end_pos": 98834185, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045643", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TNLNNCP", "url": "https://omabrowser.org/oma/group/TNLNNCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MX55", "url": "https://www.orthodb.org/?gene=G3MX55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829:SF373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829:SF373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422099", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX55-1", "url": "https://www.uniprot.org/uniprotkb/G3MX55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"protein_name": "Forkhead box protein D2", "gene_name": "foxd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLGTDMSDSSALSDDVDIDVVGGDIVKEGKYLHHHLSFHLDNDSDDNLSQNAGEGAISPGQSSLDCPADRVGQRDDSRTGALTGDKPGKNALVKPPYSYIALITMAILQSPKKRLTLSEICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRHQTNEILREAGGFLPGFGYGPYGYNYGLQLQNFHAHHPYHPHHPGSAFPFQNTHCALPTPSSIFSTPHSLPSFLGTELRKPFYPQLSPTLPGLAPLKTDTNGPSRPSFSIDNIIGAASSPASPYTTQPAGQAQILAMLTPTLASATNHLSITQETMLQPGTQTFSSKTSSLNNCHF", "length": 369 }, "evidence": [ { "id": "G3MX55", "url": "https://omabrowser.org/oma/group/G3MX55/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LP85-1", "protein_name": "Forkhead box D2", "gene_name": "Foxd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "G3MX55", "url": "https://www.uniprot.org/uniprotkb/G3MX55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MX55-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 486, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MX55-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MX55" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MX55", "database": "UniProtKB", "url": 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"id": "ENSBTAG00000048256", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048256", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04458", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04458", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "132343974", "url": "https://www.ncbi.nlm.nih.gov/gene/132343974", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:132343974", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132343974", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KACYGCH", "url": "https://omabrowser.org/oma/group/KACYGCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46109:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46109:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21890", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21890", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059738081", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738081", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX85-1", "url": "https://www.uniprot.org/uniprotkb/G3MX85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSVSNQQFAGGCAKVPEDAARAAKEPRLLHGAGICKWFNVPMGFGFLSMTACAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESLRVTGPWGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQAPSSQGKPAYFPEEEEEIHSFAMLPETQN", "length": 201, "header": "tr|G3MX85-1|G3MX85_BOVIN Isoform 1 of Protein lin-28 homolog A OS=Bos taurus OX=9913 GN=LOC132343974 PE=3 SV=1 CANONICAL=G3MX85-1" }, "isoforms": [ { "isoform_ac": "G3MX85-1", "url": "https://www.uniprot.org/uniprotkb/G3MX85/entry", "sequence": { "sequence": "MGSVSNQQFAGGCAKVPEDAARAAKEPRLLHGAGICKWFNVPMGFGFLSMTACAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESLRVTGPWGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQAPSSQGKPAYFPEEEEEIHSFAMLPETQN", "length": 201, "header": "tr|G3MX85-1|G3MX85_BOVIN Isoform 1 of Protein lin-28 homolog A OS=Bos taurus OX=9913 GN=LOC132343974 PE=3 SV=1 CANONICAL=G3MX85-1" }, "locus": { "chromosome": "26", "start_pos": 42827179, "end_pos": 42826577, "strand": "+", "evidence": [ { "database": 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"glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9VRN5-1", "protein_name": "Protein lin-28 homolog", "gene_name": "lin-28", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MENVQLENGLERRTTSQSSTSSANPANLASPTEECGCVRLGKCKWFNVAKGWGFLTPNDGGQEVFVHQSVIQMSGFRSLGEQEEVEFECQRTSRGLEATRVSSRHGGSCQGSTYRPRINRRTRRMRCYNCGEFANHIASECALGPQPKRCHRCRGEDHLHADCPHKNVTQSHSNSKSISNNSSSSAAQEKSEEAT", "length": 195 }, "evidence": [ { "id": "G3MX85", "url": "https://omabrowser.org/oma/group/G3MX85/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of miRNA-mediated gene silencing", "id": "GO:0060964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060964", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" }, { "name": "miRNA catabolic process", "id": "GO:0010587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010587", "evidence": [ { "database": "UniProtKB", "id": "G3MX85", "url": "https://www.uniprot.org/uniprotkb/G3MX85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MX85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 201, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MX85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MX85" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MX85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX85" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 145, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MX85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX85" }, { "id": "PS51857", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51857" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSD", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 103, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX87-1", "uniprot_ac": "G3MX87", "uniprot_id": "G3MX87_BOVIN", "mass": { "chemical_mass": 64459.0, "monoisotopic_mass": 64459.0 }, "refseq": { "ac": "NP_001095551", "name": "RUN and FYVE domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001095551" }, "gene_names": [ { "name": "RUFY4", "type": "recommended", "evidence": [ { "id": "G3MX87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX87" } ] }, { "name": "RUFY4", "type": "synonym", "evidence": [ { "id": "NP_001095551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001095551" } ] } ], "protein_names": [ { "name": "RUN and FYVE domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "G3MX87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX87/entry#names_and_taxonomy" } ] }, { "name": "RUN and FYVE domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "NP_001095551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001095551" } ] } ], "function": [ { "annotation": "ARL8 effector that promotes the coupling of endolysosomes to dynein-dynactin for retrograde transport along microtubules. Acts by binding both GTP-bound ARL8 and dynein-dynactin. In nonneuronal cells, promotes concentration of endolysosomes in the juxtanuclear area. In hippocampal neurons, drives retrograde transport of endolysosomes from the axon to the soma. Positive regulator of macroautophagy in dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger. Positive regulator of osteosclast bone-resorbing activity, possibly by promoting late endosome-lysosome fusion by acting as an adapter protein between RAB7A on late endosomes and LAMP2 on primary lysosomes.", "evidence": [ { "database": "UniProtKB", "id": "G3MX87", "url": "https://www.uniprot.org/uniprotkb/G3MX87#function" }, { "database": "UniProtKB", "id": "ARBA00059075", "url": "https://www.uniprot.org/uniprotkb/ARBA00059075#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX87", "url": "https://www.uniprot.org/uniprotkb/G3MX87" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RUFY4", "url": "https://www.uniprot.org/uniprotkb/G3MX87", "locus": { "chromosome": "2", "start_pos": 106175952, "end_pos": 106154128, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003327", "url": "https://www.ensembl.org/id/ENSBTAG00000003327" } ] } } ], "crossref": [ { "id": "G3MX87", "url": "https://alphafold.ebi.ac.uk/entry/G3MX87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003327", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003327", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15745", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15745", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "523588", "url": "https://www.ncbi.nlm.nih.gov/gene/523588", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523588", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523588", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "APGCCVG", "url": "https://omabrowser.org/oma/group/APGCCVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MX87", "url": "https://www.orthodb.org/?gene=G3MX87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47732:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47732:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001095551", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001095551", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MX87", "url": "https://www.uniprot.org/uniprotkb/G3MX87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX87-1", "url": "https://www.uniprot.org/uniprotkb/G3MX87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKEGAVLKMTRDLKAAVSAILQGYGAGQQPVTDTSAELHRLCGCLELLLQFDQKEQKSFLRPRKDYWDFLCAALWQQRGDTEPVRFVHSLDKLKTPLGKGRAFIRFCLAHGQLAESLQLCLLNPEFTREWYGPRSPLVCPELREDILDSLYALNGMTFDLDLQRPDLDGAWPMFSESHCSNSSRTRGRRPRKTRESPKEISATYGNSTEVHLEEPHTSQASCLQDAPRKDGLAGLPRSQQHRHHPHFLEKKKEDPRSLGCPPSMWELDGEEFQQDQEKGVPRTEICLEDSTPTIQGQGEGARETLKEVVGSEAEGKGALLGVEGQRTTKGTHEGEAERSHIHRLLASSPKGTIGDVVSWGKHDGKVPSIPGELWVLQGLGTKEDSTSEKPQEQTGVTSVTRREEQAEMALQDVVKSLRYGLQKTQEQAQHQEQMLKEQEGELKALQEQLSRCQEERARLQAELEQKQREAERKDAVYEEELGGQRDLVRAMKSRVLELIQEKDILWQKVQHLSSMAPGCCVVCSKIFGRLSRRYPCRLCGGLVCHACSVDYKKRERHCPPCSQRRDAQVL", "length": 571, "header": "tr|G3MX87-1|G3MX87_BOVIN Isoform 1 of RUN and FYVE domain-containing protein 4 OS=Bos taurus OX=9913 GN=RUFY4 PE=4 SV=2 CANONICAL=G3MX87-1" }, "isoforms": [ { "isoform_ac": "G3MX87-1", "url": "https://www.uniprot.org/uniprotkb/G3MX87/entry", "sequence": { "sequence": "MAKEGAVLKMTRDLKAAVSAILQGYGAGQQPVTDTSAELHRLCGCLELLLQFDQKEQKSFLRPRKDYWDFLCAALWQQRGDTEPVRFVHSLDKLKTPLGKGRAFIRFCLAHGQLAESLQLCLLNPEFTREWYGPRSPLVCPELREDILDSLYALNGMTFDLDLQRPDLDGAWPMFSESHCSNSSRTRGRRPRKTRESPKEISATYGNSTEVHLEEPHTSQASCLQDAPRKDGLAGLPRSQQHRHHPHFLEKKKEDPRSLGCPPSMWELDGEEFQQDQEKGVPRTEICLEDSTPTIQGQGEGARETLKEVVGSEAEGKGALLGVEGQRTTKGTHEGEAERSHIHRLLASSPKGTIGDVVSWGKHDGKVPSIPGELWVLQGLGTKEDSTSEKPQEQTGVTSVTRREEQAEMALQDVVKSLRYGLQKTQEQAQHQEQMLKEQEGELKALQEQLSRCQEERARLQAELEQKQREAERKDAVYEEELGGQRDLVRAMKSRVLELIQEKDILWQKVQHLSSMAPGCCVVCSKIFGRLSRRYPCRLCGGLVCHACSVDYKKRERHCPPCSQRRDAQVL", "length": 571, "header": "tr|G3MX87-1|G3MX87_BOVIN Isoform 1 of RUN and FYVE domain-containing protein 4 OS=Bos taurus OX=9913 GN=RUFY4 PE=4 SV=2 CANONICAL=G3MX87-1" }, "locus": { "chromosome": "2", "start_pos": 106175484, "end_pos": 106156427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063006.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063006.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054147.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054147.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:523588", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523588", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M513-1", "protein_name": "RUN and FYVE domain-containing protein 4", "gene_name": "Rufy4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEKETILKISRNLKNAVSAILQGYGDGQGPVTDTSAELHRLCGCLELLLQFDQKEQRSFLGARKDYWDFLFTALRRQRGYTEQMNFICSQDKLKTSLGKGRAFIRLCLAHGQLAESMQLCLLNPQLTREWYGPRSPLLCPELQGDILDSLYTLNGVAFNLDLQRPDLDEAWPMFSESHYSSPSRTRERRPRKPKGFPEEVRCSKGQQLQGPEAGGTSCLQDATTEDLPPDLRTPLQQDHLPTFLEEKREDSRSLSCPQSIWETGREGFRLDQEGGPKTRKLLENSTASIQQQKGGAKDVQMQLTGRKDEGKGSLPGTEGRKTTEGIQERATDWNHAQELLAPSLQGREEDAELGYRHGWDQPGALGQSWVLGSKKGPTTGKPQEWTGVTRATVQKDQTEVPLQQEVIKEPGYGLQLTEVQAQCQEQLQAQEGELQALQEQLSRCQEERALLQAMLEQKQQEAERRAAMYEKELEGQRDLVQAMKRRVLELIQEKDHQWQRLQQLSTVTPGHCMGCNKVFRRLSRRYPCRLQEERALLPSLCPAGRNPGHLTKIAQGT", "length": 558 }, "evidence": [ { "id": "G3MX87", "url": "https://omabrowser.org/oma/group/G3MX87/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TYX8-1", "protein_name": "RUN and FYVE domain-containing protein 4", "gene_name": "Rufy4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANNGTILKISRSLKNAVSAILQGYGDGQEPVTETSAELHRLCGCLELLLQFDQKEQRSFLGARKDYWDFLFTALRRHRGYTEQMSFICSQDKLKTSLGKGRAFIRLCLARGQLAESMQLCLLNPQLTREWYGPRSPLLCAELQEDILDSLYALNGVAFNLDLQRPDLDEAWPMFSESRCSSPSRTGKRRPGKPKGFPEEVRCSRGEQLQEPDTGGTSCLQDATREDRTPDLCKPLQPSHLPTFLEEKREDSRSLSCPQSTWETEREGFQLDQKDGGPKPRKFLENSTASIQQQRSRAKDVKMQLTGRKVEGKGSLSGTEDQRTTEGIQKRAADWDLGQGLMAPGLQGREDAELGYRCEWNQPDVLRQSWVLGTKKSSPTEKPQEWTGVTSGTMQEDGSEVPLQQEVIKDPGYGLQLAKEQAQCQEQLRAQEAELQALQEQLSRCQKERALLQVKLEQKQQEAERRDAMYQTELEGQRDLVQAMKRRVLELIHEKDLQWQRLQQLSTVAPGHCIGCNKVFRRLSRRYPCRLCGGLVCHACSVDYKKRERCCPTCAQQEEIQDT", "length": 563 }, "evidence": [ { "id": "G3MX87", "url": "https://omabrowser.org/oma/group/G3MX87/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZNE9-2", "protein_name": "RUN and FYVE domain-containing protein 4", "gene_name": "RUFY4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEEGAILKVTKDLRAAVSAILQGYGDGQGPVTDTSAELHRLCGCLELLLQFDQKEQKSFLGPRKDYWDFLCTALRRQRGNMEPIHFVRSQDKLKTPLGKGRAFIRFCLARGQLAEALQLCLLNSELTREWYGPRSPLLCPERQEDILDSLYALNGVAFELDLQQPDLDGAWPMFSESRCSSSTQTQGRRPRKNKDAPKKIPAAYGGPENVQIEDSHTSQAICLQDAPSGQQLAGLPRSQQQRHLPFFLEKKGESSRKHRYPQSMWEPEGKELQLDQEERAPWIEIFLGNSTPSTQGQGKGAMGTQKEVIGMEAEVTGVLLVAEGQRTTEGTHKKEAEWSHVQRLLMPSPRGAVEGAVSGSRQGSGGSSILGEPWVLQGHATKEDSTVENPQVQTEVTLVARREEQAEVSLQDEIKSLRLGLRKAEEQAQRQEQLLREQEGELQALREQLSRCQEERAELQAQLEQKQQEAERRDAMYQEELGGQRDLVQAMKRRVLELIQEKDRLWQRLQHLSSMAPECCVACSKIFGRFSRRYPCRLCGGLLCHACSMDYKKRDRCCPPCAQGREAQVT", "length": 571 }, "evidence": [ { "id": "G3MX87", "url": "https://omabrowser.org/oma/group/G3MX87/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "multivesicular body-lysosome fusion", "id": "GO:0061763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061763", "evidence": [ { "database": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"categories": [ "Protein" ] }, { "id": "G3MXA1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "length": 359, "header": "tr|G3MXA1-1|G3MXA1_BOVIN Isoform 1 of Mab-21 like 2 OS=Bos taurus OX=9913 GN=MAB21L2 PE=3 SV=1 CANONICAL=G3MXA1-1" }, "isoforms": [ { "isoform_ac": "G3MXA1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXA1/entry", "sequence": { "sequence": "MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "length": 359, "header": "tr|G3MXA1-1|G3MXA1_BOVIN Isoform 1 of Mab-21 like 2 OS=Bos taurus OX=9913 GN=MAB21L2 PE=3 SV=1 CANONICAL=G3MXA1-1" }, "locus": { "chromosome": "17", "start_pos": 7224090, "end_pos": 7223354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063599.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063599.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054164.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054164.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539225", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539225", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XZD8-1", "protein_name": "Mab-21 like 2", "gene_name": "MAB21L2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "length": 359 }, "evidence": [ { "id": "G3MXA1", "url": "https://omabrowser.org/oma/group/G3MXA1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACZ1-1", "protein_name": "Mab-21 like 2", "gene_name": "Mab21l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "length": 359 }, "evidence": [ { "id": "G3MXA1", "url": "https://omabrowser.org/oma/group/G3MXA1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F2Z5C6-1", "protein_name": "Mab-21 like 2", "gene_name": "MAB21L2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "length": 359 }, "evidence": [ { "id": "G3MXA1", "url": "https://omabrowser.org/oma/group/G3MXA1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BPP1-1", "protein_name": "Protein mab-21-like 2", "gene_name": "Mab21l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "length": 359 }, "evidence": [ { "id": "G3MXA1", "url": "https://omabrowser.org/oma/group/G3MXA1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8UUZ1-1", "protein_name": "Protein mab-21-like 2", "gene_name": "mab21l2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIATQAKLVYQLNKYYNERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGMEVIAPNEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFAEAENRLLMSGCRKKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALETAAKQTWRLAREILTNAKSLDKL", "length": 359 }, "evidence": [ { "id": "G3MXA1", "url": "https://omabrowser.org/oma/group/G3MXA1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9Y106-1", "protein_name": "Protein mab-21-like", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLVPPDMMAAQTRMVYQMNRFCTERVQARMYKTATAIREICKIVQDILKEVELQEPRFISSLVECNGRFEGVEVISPNEFEIVLYLNQMGVFNFVDDGTLPGCAVLKLSDGRKRSMSLWVEFITASGYLSSRKIRARFQTLVAQACDKSVYRDMVKMVGDTSEVKLRIRERFVVQITPAFKCSGIWPRSAAHWPVPHLPWPHPNIVAEVKTEGFDLLSKESVIMQNKNNNAASMEGDAWVLSFFEAENRLLQGGCRRRCLSMLKTLRDRHLDLPGNPISAYHLKNLLLYECEKHPRDFEWDEGCIADRINGIFLQLISCLQYRRCPHYFLPALDMFKGKSPSALEQAAKQVWRLTRELLTNANAFEKL", "length": 368 }, "evidence": [ { "id": "G3MXA1", "url": "https://omabrowser.org/oma/group/G3MXA1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y586-1", "protein_name": "Protein mab-21-like 2", "gene_name": "MAB21L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL", "length": 359 }, "evidence": [ { "id": "G3MXA1", "url": "https://omabrowser.org/oma/group/G3MXA1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MXA1", "url": "https://www.uniprot.org/uniprotkb/G3MXA1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MXA1", "url": "https://www.uniprot.org/uniprotkb/G3MXA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "G3MXA1", "url": "https://www.uniprot.org/uniprotkb/G3MXA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXA1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 359, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXA1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXA1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXA1" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 343, "start_aa": "Cys", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXA1" }, { "id": "PF03281", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like nucleotidyltransferase", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 243, "start_aa": "Arg", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXD0-1", "uniprot_ac": "G3MXD0", "uniprot_id": "G3MXD0_BOVIN", "mass": { "chemical_mass": 60755.0, "monoisotopic_mass": 60755.0 }, "refseq": { "ac": "XP_024842698", "name": "interferon regulatory factor 2-binding protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842698" }, "gene_names": [ { "name": "IRF2BP2", "type": "recommended", "evidence": [ { "id": "G3MXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ] }, { "name": "IRF2BP2", "type": "synonym", "evidence": [ { "id": "XP_024842698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842698" } ] } ], "protein_names": [ { "name": "Interferon regulatory factor 2 binding protein 2", "type": "synonym", "evidence": [ { "id": "G3MXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXD0/entry#names_and_taxonomy" } ] }, { "name": "interferon regulatory factor 2-binding protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024842698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842698" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IRF2BP2", "url": "https://www.uniprot.org/uniprotkb/G3MXD0", "locus": { "chromosome": "28", "start_pos": 7400010, "end_pos": 7403585, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046841", "url": "https://www.ensembl.org/id/ENSBTAG00000046841" } ] } } ], "crossref": [ { "id": "G3MXD0", "url": "https://alphafold.ebi.ac.uk/entry/G3MXD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046841", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046841", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "781665", "url": "https://www.ncbi.nlm.nih.gov/gene/781665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:781665", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKKEPGM", "url": "https://omabrowser.org/oma/group/FKKEPGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXD0", "url": "https://www.orthodb.org/?gene=G3MXD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10816", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10816:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024842698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXD0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPPGAAAPAAAKPPPLSAKDLLLQQQQQLGHGGPEAAPRAPQALERYPLAAAAAERPPRLGSDFGGSRPAAALAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPAALGLGGRAAASLAAVSGAAAAGLGSAQPAEMGAHKRPASVSSSAAAEHEQREAAAKEKQPPAASHRGPADSLSTAAGAAELGSEGAGKGRGPGEQDWVNRPKTVRDTLLALHQHGHSAPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPITPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSSSPPSPSSMNQRRLGPREVGGQGAGSAGGLEPVHPASLPDSSLAASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "length": 588, "header": "tr|G3MXD0-1|G3MXD0_BOVIN Isoform 1 of Interferon regulatory factor 2 binding protein 2 OS=Bos taurus OX=9913 GN=IRF2BP2 PE=3 SV=2 CANONICAL=G3MXD0-1" }, "isoforms": [ { "isoform_ac": "G3MXD0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXD0/entry", "sequence": { "sequence": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPPGAAAPAAAKPPPLSAKDLLLQQQQQLGHGGPEAAPRAPQALERYPLAAAAAERPPRLGSDFGGSRPAAALAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPAALGLGGRAAASLAAVSGAAAAGLGSAQPAEMGAHKRPASVSSSAAAEHEQREAAAKEKQPPAASHRGPADSLSTAAGAAELGSEGAGKGRGPGEQDWVNRPKTVRDTLLALHQHGHSAPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPITPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSSSPPSPSSMNQRRLGPREVGGQGAGSAGGLEPVHPASLPDSSLAASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "length": 588, "header": "tr|G3MXD0-1|G3MXD0_BOVIN Isoform 1 of Interferon regulatory factor 2 binding protein 2 OS=Bos taurus OX=9913 GN=IRF2BP2 PE=3 SV=2 CANONICAL=G3MXD0-1" }, "locus": { "chromosome": "28", "start_pos": 7403386, "end_pos": 7401014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063370.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063370.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054195.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054195.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 405, "start_aa": "Thr", "end_pos": 405, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr405", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:781665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781665", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AKG8-1", "protein_name": "Interferon regulatory factor 2 binding protein 2", "gene_name": "IRF2BP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPPGAAAPAAAKPPPLSAKDLLLQQQQQLGHGGPEATARAPQALERYPLAAAAAERPPRLGSDFSGSRPAAGLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSTTPLPAALGLGGRAAASLAAVSGAAAAGLGSAQPAELGAHKRPASVTSSASAEHEQREAAAKEKQPPPTSHRGPADSLTTAAGAAELGTEGAGKGRGPGDQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPITPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSSSPPSPSSMNQRRLGPREVGGQGAGSTGGLEPVHPASLPDSSLAASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "length": 588 }, "evidence": [ { "id": "G3MXD0", "url": "https://omabrowser.org/oma/group/G3MXD0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZR43-1", "protein_name": "Interferon regulatory factor 2 binding protein 2", "gene_name": "Irf2bp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFQEGRSPTGAQPASAKPPPLSAKDLLLQPPPQLGHAGAEAARAQAMERYPLAPDRAPRLASEFSTRAGAGLPQSAASQPSPANGILVPNGFSKLEEPPELNRQSPNPRRAHAVPPTLVPLVNGSAALGLSGRAAATLAAVSGTPGLGAQPAELGTHKRPASVSSAAAEHEAREQSKEKAQPAHRSPADSLSGTTGASELSAESAGKGRAPGEQDWASRPKTVRDTLLALHHQHGHSGPFESKFKKEPALTAAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPITPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDTTQVHSTTRRNSSSPPSPSSMNQRRLGPREVGGQATGSTGGLEPVHPASLPDSSLAASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "length": 571 }, "evidence": [ { "id": "G3MXD0", "url": "https://omabrowser.org/oma/group/G3MXD0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XZF3-1", "protein_name": "Interferon regulatory factor 2 binding protein 2", "gene_name": "IRF2BP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSAAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIDTARQLKRAHGCFAEGRAPPPPHAKQPPLSAKELLAQQQQLGHPSAAAEAAARPPPQPLERYPLAAERPPPRLGAEYGGGRQVNGILVPNGFPKPEEPPELNRQSPNPRRTHAVPPTLVPLVNGAGLPAAIGGLGGRAAAASLAAISAAPAPLAVPVPQQPAAAAQAAAGQPGELGHKRPGSVSSSSSGGGGGGAAGEHDGGGKEKRGSAESMPAAAEMGAEGKSRAGGEEWLAKPKTVRDTLLALHQHGGHAVPPFDSKFKKEPGMAGGRLLGYESNGAAAKPGARAARKRKPSPEPEGEAGPPKINGEAQPWLPAASEGMKMPLTATSFMSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGNHASKEANQVHSTTRRNSSSPPSPSAMNQRRLGPGREVPGQGGSAAGGLEPVHPASLPDSSLAASVPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "length": 574 }, "evidence": [ { "id": "G3MXD0", "url": "https://omabrowser.org/oma/group/G3MXD0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9Q1P8-1", "protein_name": "Interferon regulatory factor 2-binding protein 2", "gene_name": "Irf2bp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPTGAQPAAAKPPPLSAKDLLLQPPPQLGHAGAEAARAQAMERYPLAPDRAPRLASDFSTRAGAGLPQSAAQQSAPANGILVPNGFSKLEEPPELNRQSPNPRRAHAVPPTLVPLVNGSAALGLSGRAAATLAAVSGTPGLGAQPAELGTHKRPASVSSAAAEHEAREPSKEKAQPAHRSPADSLSSAAGASELSAEGAGKGRAPGEQDWASRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGETQPWLSTSTEGLKIPITPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDATQVHSTTRRNSSSPPSPSSMNQRRLGPREVGGQATGSTGGLEPVHPASLPDSSLAASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "length": 570 }, "evidence": [ { "id": "G3MXD0", "url": "https://omabrowser.org/oma/group/G3MXD0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z5L9-1", "protein_name": "Interferon regulatory factor 2-binding protein 2", "gene_name": "IRF2BP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS", "length": 587 }, "evidence": [ { "id": "G3MXD0", "url": "https://omabrowser.org/oma/group/G3MXD0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "immature B cell differentiation", "id": "GO:0002327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002327", "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "G3MXD0", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXD0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 588, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXD0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXD0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" }, { "id": "PF25457", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25457" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRF-2BP1/2-like middle", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 343, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" }, { "id": "PF25454", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25454" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Interferon regulatory factor 2-binding protein 1/2-like C3HC4 zinc finger", "eco_id": "ECO_0000259", "start_pos": 505, "end_pos": 576, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXD0" }, { "id": "PF11261", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Interferon regulatory factor 2-binding protein 1/2-like zinc finger", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 63, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 395, 405 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 455, "end_pos": 457 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXE1-1", "uniprot_ac": "G3MXE1", "uniprot_id": "G3MXE1_BOVIN", "mass": { "chemical_mass": 8351.0, "monoisotopic_mass": 8351.0 }, "refseq": { "ac": "XP_059742048", "name": "ATP synthase subunit e, mitochondrial-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742048" }, "gene_names": [ { "name": "LOC132345191", "type": "recommended", "evidence": [ { "id": "G3MXE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXE1" } ] }, { "name": "LOC132345191", "type": "synonym", "evidence": [ { "id": "XP_059742048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742048" } ] } ], "protein_names": [ { "name": "ATP synthase F(0) complex subunit e, mitochondrial", "type": "recommended", "evidence": [ { "id": "G3MXE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXE1/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase subunit e, mitochondrial-like", "type": "synonym", "evidence": [ { "id": "XP_059742048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059742048" } ] } ], "function": [ { "annotation": "Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.", "evidence": [ { "database": "UniProtKB", "id": "G3MXE1", "url": "https://www.uniprot.org/uniprotkb/G3MXE1#function" }, { "database": "UniProtKB", "id": "RU367005", "url": "https://www.uniprot.org/uniprotkb/RU367005#function" }, { "database": "UniProtKB", "id": "ARBA00057306", "url": "https://www.uniprot.org/uniprotkb/ARBA00057306#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXE1", "url": "https://www.uniprot.org/uniprotkb/G3MXE1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132345191", "url": "https://www.uniprot.org/uniprotkb/G3MXE1", "locus": {} } ], "crossref": [ { "id": "G3MXE1", "url": "https://alphafold.ebi.ac.uk/entry/G3MXE1", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3MXE1", "url": "https://www.uniprot.org/uniprotkb/G3MXE1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "G3MXE1", "url": "https://www.uniprot.org/uniprotkb/G3MXE1" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "G3MXE1", "url": "https://www.uniprot.org/uniprotkb/G3MXE1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton transmembrane transporter activity", "id": "GO:0015078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015078", "evidence": [ { "database": "UniProtKB", "id": "G3MXE1", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377456" }, "gene_names": [ { "name": "OR6C5", "type": "recommended", "evidence": [ { "id": "G3MXH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH0" } ] }, { "name": "OR6C5", "type": "synonym", "evidence": [ { "id": "NP_001377456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377456" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MXH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 6 subfamily C member 5", "type": "synonym", "evidence": [ { "id": "NP_001377456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377456" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377456" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MXH0", "url": "https://www.uniprot.org/uniprotkb/G3MXH0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXH0", "url": "https://www.uniprot.org/uniprotkb/G3MXH0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR6C5", "url": "https://www.uniprot.org/uniprotkb/G3MXH0", "locus": { "chromosome": "5", "start_pos": 58889511, "end_pos": 58890449, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000056539", "url": "https://www.ensembl.org/id/ENSBTAG00000056539" } ] } } ], "crossref": [ { "id": "G3MXH0", "url": "https://alphafold.ebi.ac.uk/entry/G3MXH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787945", "url": "https://www.ncbi.nlm.nih.gov/gene/787945", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"https://www.uniprot.org/uniprotkb/G3MXH0/entry", "sequence": { "sequence": "MRNHTMLTEFVLLGISDNPELQVVIFIFLFLAYVLSVVGNLTIIILTLTDCHLKTPMYYFLRNFSFLEITFTSVSIPRFLGAIITKVKTISYNNCLAQLFFFIFMGVSEFFLLTAMSYDRYAAICKPLHYTTIMNKKICTLLVFSSWLGGFLTIFPPLMLILQLDFCASNIIDHFSCDYFPILRLSCSDTWLLEMIGFYFAFVTLLFTLALVILSYMCIITTILRIPSATQRKKAFSTCSSHMIVISISYGSCIFMYVKPSAKERASLTKGVAILNTSIAPMLNPFIYTLRNEQVKQALKNLVHKVILSRNK", "length": 312, "header": "tr|G3MXH0-1|G3MXH0_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR6C5 PE=3 SV=1 CANONICAL=G3MXH0-1" }, "locus": { "chromosome": "5", "start_pos": 58890449, "end_pos": 58889514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065594.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065594.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054237.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054237.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:787945", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787945", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AMX2-1", "protein_name": "Olfactory receptor", "gene_name": "Olr906", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNHSRITDFVLLGISDTPEVQILIFILLFIAYILSVTGNLTIIILTLLDSQLKTPMYFFLQNFSFLEIIFTSVSIPRFLESIITKVKTISYNNCLAQLYFFLSLGVSEFFLLTAMSYDRYVAICKPLHYVIIMNQKVCTLLVLTSWLAGFLSIFPLIMLILKLDFCASNTIDHFSCDYSPILQLSCSDTKHLEAFGLYCASITLLFTLALVILSYICIISTILKFPSASQRKKAFSTCSSHMIVISISYGSCIFMYVKPSANERASLTKGVAVLNTSIAPMLNPFIYTLRNQQVKQAFKDLINRVMFNRKK", "length": 312 }, "evidence": [ { "id": "G3MXH0", "url": "https://omabrowser.org/oma/group/G3MXH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TRI1-1", "protein_name": "Olfactory receptor", "gene_name": "Or6c5c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNHSVITEFVLLGISDDPEVQVVIFILLFIAYILSVTGNLTIIILTLLDSQLKTPMYFFLQNFSFLEIIFTSVSIPRFLESIITKVKTISYNNCLAQLYFFISMGVSEFFLLTAMSYDRYVAICKPLHYTLIMNQKVCTLLVLASWLAGFLTIFPPLMLVLKLDFCASNVIDHFSCDYFPILQLSCSDTRSLEMIGFYFAFITLLFTLALVILSYISIISTILRFPSASQRKKAFSTCSSHMIVISISYGSCIFMYVKPSANERASLTKGVAVLNTSIAPMLNPFIYSLRNEQVKQAFKDLINKVVLYRSK", "length": 312 }, "evidence": [ { "id": "G3MXH0", "url": "https://omabrowser.org/oma/group/G3MXH0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3MXH0", "url": "https://www.uniprot.org/uniprotkb/G3MXH0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MXH0", "url": "https://www.uniprot.org/uniprotkb/G3MXH0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MXH0", "url": "https://www.uniprot.org/uniprotkb/G3MXH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXH0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXH0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXH0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXH4-1", "uniprot_ac": "G3MXH4", "uniprot_id": "G3MXH4_BOVIN", "mass": { "chemical_mass": 67838.0, "monoisotopic_mass": 67838.0 }, "refseq": { "ac": "XP_015329415", "name": "zinc finger protein ZIC 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329415" }, "gene_names": [ { "name": "ZIC5", "type": "recommended", "evidence": [ { "id": "G3MXH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH4" } ] }, { "name": "ZIC5", "type": "synonym", "evidence": [ { "id": "XP_015329415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329415" } ] } ], "protein_names": [ { "name": "Zinc finger protein ZIC 5", "type": "recommended", "evidence": [ { "id": "G3MXH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH4/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein of the cerebellum 5", "type": "synonym", "evidence": [ { "id": "G3MXH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein ZIC 5", "type": "synonym", "evidence": [ { "id": "XP_015329415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329415" } ] } ], "function": [ { "annotation": "Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.", "evidence": [ { "database": "UniProtKB", "id": "G3MXH4", "url": "https://www.uniprot.org/uniprotkb/G3MXH4#function" }, { "database": "UniProtKB", "id": "ARBA00057768", "url": "https://www.uniprot.org/uniprotkb/ARBA00057768#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXH4", "url": "https://www.uniprot.org/uniprotkb/G3MXH4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZIC5", "url": "https://www.uniprot.org/uniprotkb/G3MXH4", "locus": { "chromosome": "12", "start_pos": 76720781, "end_pos": 76728312, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046271", "url": "https://www.ensembl.org/id/ENSBTAG00000046271" } ] } } ], "crossref": [ { "id": "G3MXH4", "url": "https://alphafold.ebi.ac.uk/entry/G3MXH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046271", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046271", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "787451", "url": "https://www.ncbi.nlm.nih.gov/gene/787451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:787451", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787451", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPLQNMT", "url": "https://omabrowser.org/oma/group/QPLQNMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXH4", "url": "https://www.orthodb.org/?gene=G3MXH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015329415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015329415", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXH4", "url": "https://www.uniprot.org/uniprotkb/G3MXH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXH4-1", "url": "https://www.uniprot.org/uniprotkb/G3MXH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLRAGREGKKVPPGRVHGSDCVALMEPPLSKRNPPAPRLADPAAARAWPLQNMTGFPALASAPAHSRVRASAAHLRLRDPVADPGVARAPLRPEHMAQASAPGPRPPSQALPAPPESPAAAARAAASAVHPGARTAPGGGGARGGPSPAPPPPAPPPPPSPSPPPPPPPPPTPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEPRSGPGSPQHPAPPPASGGMFISASGTYAGPDGGGGGGPALFPSLHEPPGGPGGHPHPLNGQMRLGLAAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAAAATGPGPHLQHHAPPPAPPPPPAPAQQPPHLPGAAGAFLRYMRQPIKQELICKWIDSEELAGPPPPPPPAGGSKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKVRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQAGGAPSHLHAPSSNGTTSESDDEDMYANPEVVRTIH", "length": 662, "header": "tr|G3MXH4-1|G3MXH4_BOVIN Isoform 1 of Zinc finger protein ZIC 5 OS=Bos taurus OX=9913 GN=ZIC5 PE=3 SV=2 CANONICAL=G3MXH4-1" }, "isoforms": [ { "isoform_ac": "G3MXH4-1", "url": "https://www.uniprot.org/uniprotkb/G3MXH4/entry", "sequence": { "sequence": "MFLRAGREGKKVPPGRVHGSDCVALMEPPLSKRNPPAPRLADPAAARAWPLQNMTGFPALASAPAHSRVRASAAHLRLRDPVADPGVARAPLRPEHMAQASAPGPRPPSQALPAPPESPAAAARAAASAVHPGARTAPGGGGARGGPSPAPPPPAPPPPPSPSPPPPPPPPPTPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEPRSGPGSPQHPAPPPASGGMFISASGTYAGPDGGGGGGPALFPSLHEPPGGPGGHPHPLNGQMRLGLAAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAAAATGPGPHLQHHAPPPAPPPPPAPAQQPPHLPGAAGAFLRYMRQPIKQELICKWIDSEELAGPPPPPPPAGGSKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKVRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQAGGAPSHLHAPSSNGTTSESDDEDMYANPEVVRTIH", "length": 662, "header": "tr|G3MXH4-1|G3MXH4_BOVIN Isoform 1 of Zinc finger protein ZIC 5 OS=Bos taurus OX=9913 GN=ZIC5 PE=3 SV=2 CANONICAL=G3MXH4-1" }, "locus": { "chromosome": "12", "start_pos": 76728113, "end_pos": 76721785, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064715.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064715.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054241.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054241.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:787451", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787451", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZJD4-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "Zic5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLAGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQTSGHGPSPPTQALPELPQATAPAARSPASGTHPGARTHHDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPPALSGYTATNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDGGGSALFPALHDSPGAPGGHPLNGQMRLGLAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAPHPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAGPPAPADSGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDTLSPVLDPTRSRSSTLSPQVTNLNEWYVCQAGGAPSHLHTPSSNGTTSESEDEEMYGNPEVMRTIH", "length": 623 }, "evidence": [ { "id": "G3MXH4", "url": "https://omabrowser.org/oma/group/G3MXH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RP23-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "ZIC5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFLRAGRGKKVPPVRVYGSDCVVVMEPPLSKRNTPALRLADLATAQARPLQNMTGFPALASPSAHSQLRATAAHLRPRDLGADPGVAITPLGPEHMAQASALGLSPPSQALPAQPEAPAAAARAAASVAHPGAGTYPGGGGSSSVQSSAPPPPAPPLPPSPSPPSPPSPSPSPPPPALSGYTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHSAPPPHSAGMFISASGTYAGPDGSGGGGPALFPALHDPPGGPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSLGTPGGAPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSESEDEEMYGNSEVVRTMH", "length": 661 }, "evidence": [ { "id": "G3MXH4", "url": "https://omabrowser.org/oma/group/G3MXH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7TQ40-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "Zic5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLVGPPAHSQRRAVAMHLHPRDLGTDPGVASTALGPEHMAQASGQGPCPPSQGLPGLFQVPAPAARSVASGTHPGARTHPDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPALSGYTATNSGGGSSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDGGGSALFPALHDSPGAPGGHPLNGQMRLGLAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAPHPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAGPPASADSGVKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSESEDEEMYGNPEVMRTIH", "length": 622 }, "evidence": [ { "id": "G3MXH4", "url": "https://omabrowser.org/oma/group/G3MXH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96T25-1", "protein_name": "Zinc finger protein ZIC 5", "gene_name": "ZIC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPPLSKRNPPALRLADLATAQVQPLQNMTGFPALAGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGPLGYSSVGTPVGAPLSPVLDPARSHSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSETEDEEIYGNPEVVRTIH", "length": 639 }, "evidence": [ { "id": "G3MXH4", "url": "https://omabrowser.org/oma/group/G3MXH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXH4", "url": "https://www.uniprot.org/uniprotkb/G3MXH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MXH4", "url": "https://www.uniprot.org/uniprotkb/G3MXH4" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "G3MXH4", "url": "https://www.uniprot.org/uniprotkb/G3MXH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc 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"start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXH4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 662, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXH4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXH4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 462, "end_pos": 489, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 173 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 533, "end_pos": 535 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 640, "end_pos": 642 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXH9-1", "uniprot_ac": "G3MXH9", "uniprot_id": "G3MXH9_BOVIN", "mass": { "chemical_mass": 16119.0, "monoisotopic_mass": 16119.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ATPase inhibitor, mitochondrial", "type": "recommended", "evidence": [ { "id": "G3MXH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH9/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase F1 subunit epsilon", "type": "synonym", "evidence": [ { "id": "G3MXH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.", "evidence": [ { "database": "UniProtKB", "id": "G3MXH9", "url": "https://www.uniprot.org/uniprotkb/G3MXH9#function" }, { "database": "UniProtKB", "id": "ARBA00046200", "url": "https://www.uniprot.org/uniprotkb/ARBA00046200#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXH9", "url": "https://www.uniprot.org/uniprotkb/G3MXH9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3MXH9", "locus": {} } ], "crossref": [ { "id": "G3MXH9", "url": "https://alphafold.ebi.ac.uk/entry/G3MXH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048231", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048231", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FITAKTW", "url": "https://omabrowser.org/oma/group/FITAKTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48417", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48417", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48417:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48417:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MXH9", "url": "https://www.uniprot.org/uniprotkb/G3MXH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXH9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IAALFITAKTWKQPTYGVGGTEAAPRAKPLGPARPEAPARNWQIISAGWVWDAGGAFGKGERAEEKRSFRARARELQLAALKKHRENEISHHAKETDCLKRETERHKRSIKKLKRRDDGGQVHTVLRGMATYYCPLLCGLCVDT", "length": 144, "header": "tr|G3MXH9-1|G3MXH9_BOVIN Isoform 1 of ATPase inhibitor, mitochondrial OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3MXH9-1" }, "isoforms": [ { "isoform_ac": "G3MXH9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXH9/entry", "sequence": { "sequence": "IAALFITAKTWKQPTYGVGGTEAAPRAKPLGPARPEAPARNWQIISAGWVWDAGGAFGKGERAEEKRSFRARARELQLAALKKHRENEISHHAKETDCLKRETERHKRSIKKLKRRDDGGQVHTVLRGMATYYCPLLCGLCVDT", "length": 144, "header": "tr|G3MXH9-1|G3MXH9_BOVIN Isoform 1 of ATPase inhibitor, mitochondrial OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3MXH9-1" }, "locus": { "chromosome": "25", "start_pos": 38609837, "end_pos": 38609166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064282.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064282.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054246.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054246.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3MXH9", "url": "https://www.uniprot.org/uniprotkb/G3MXH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATPase inhibitor activity", "id": "GO:0042030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042030", "evidence": [ { "database": "UniProtKB", "id": "G3MXH9", "url": "https://www.uniprot.org/uniprotkb/G3MXH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXH9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 144, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXH9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXH9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXI1-1", "uniprot_ac": "G3MXI1", "uniprot_id": "G3MXI1_BOVIN", "mass": { "chemical_mass": 34553.0, "monoisotopic_mass": 34553.0 }, "refseq": { "ac": "NP_001377740", "name": "olfactory receptor family 5 subfamily AZ member 2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377740" }, "gene_names": [ { "name": "OR5AZ2", "type": "recommended", "evidence": [ { "id": "G3MXI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXI1" } ] }, { "name": "OR5AZ2", "type": "synonym", "evidence": [ { "id": "NP_001377740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377740" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MXI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXI1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 5 subfamily AZ member 2", "type": "synonym", "evidence": [ { "id": "NP_001377740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377740" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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"description": "Antimicrobial peptides" }, { "id": "R-BTA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HHR5-1", "protein_name": "Myeloblastin", "gene_name": "LOC100752428", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGSHRSLSRVHPFLLLALVFGGAVQASQIVGGHEAQPHSRPYMASLQLSRSPGNHFCGGTLIHRRFVLTAAHCLQDIPWQLVTVVLGAHDLQSQEPEQQKFTITQIFQNNYNPEESLNDVLLIQLNRPASLGEKVAVASLPQQGQSLSQGTQCLAMGWGRLGTRAPTPRVLQELNVTVVTFLCREHNVCTLVPRRAAGVCFGDSGGPLICDGILHGVDSFVIRECASLQFPDFFARVSTYVDWIHTVLRGAAP", "length": 254 }, "evidence": [ { "id": "G3MXK8", "url": "https://omabrowser.org/oma/group/G3MXK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D0VTQ5-1", "protein_name": "Proteinase 3", "gene_name": "PRTN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRSCRPSSPALAPVLLALLLGGAARAVEIVGGQEAQPHSRPYVASLQLPWPPNSHFCGGTLIHPSFVLTAAHCLNTMNPTRVNVVLGAHNLQTPEPTQQIFRIARLFENNYDPQQKLNDVLLLQLDRPATLNTQVAVAQLPQQDQLLPHGTRCLAMGWGRLGTLEPQPRVLQELNVTVVTFLCRPQNVCTFVPQRSAGICFGDSGGPLICDGVLQGVDSFVIRGCATGQFPDFFARVALYVNWIHSVLRSVGGEDGPGAPNQNPHRR", "length": 268 }, "evidence": [ { "id": "G3MXK8", "url": "https://omabrowser.org/oma/group/G3MXK8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P24158-1", "protein_name": "Myeloblastin", "gene_name": "PRTN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP", "length": 256 }, "evidence": [ { "id": "G3MXK8", "url": "https://omabrowser.org/oma/group/G3MXK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61096-1", "protein_name": "Myeloblastin", "gene_name": "Prtn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSYPSPKGIHPFLLLALVVGGAVQASKIVGGHEARPHSRPYVASLQLSRFPGSHFCGGTLIHPRFVLTAAHCLQDISWQLVTVVLGAHDLLSSEPEQQKFTISQVFQNNYNPEENLNDVLLLQLNRTASLGKEVAVASLPQQDQTLSQGTQCLAMGWGRLGTQAPTPRVLQELNVTVVTFLCREHNVCTLVPRRAAGICFGDSGGPLICNGILHGVDSFVIRECASLQFPDFFARVSMYVDWIQNVLRGAEP", "length": 254 }, "evidence": [ { "id": "G3MXK8", "url": "https://omabrowser.org/oma/group/G3MXK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "plasma membrane raft", "id": "GO:0044853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044853", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "azurophil granule lumen", "id": "GO:0035578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035578", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "membrane protein ectodomain proteolysis", "id": "GO:0006509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006509", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "negative regulation of phagocytosis", "id": "GO:0050765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050765", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "mature conventional dendritic cell differentiation", "id": "GO:0097029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097029", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "cell-cell junction maintenance", "id": "GO:0045217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045217", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" }, { "name": "neutrophil extravasation", "id": "GO:0072672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072672", "evidence": [ { "database": "UniProtKB", "id": "G3MXK8", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXK8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 256, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXK8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXK8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXK8" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 248, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXM9-1", "uniprot_ac": "G3MXM9", "uniprot_id": "G3MXM9_BOVIN", "mass": { "chemical_mass": 53805.0, "monoisotopic_mass": 53805.0 }, "refseq": { "ac": "XP_002685658", "name": "zinc finger and BTB domain-containing protein 8B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685658" }, "gene_names": [ { "name": "ZBTB8B", "type": "recommended", "evidence": [ { "id": "G3MXM9", "database": "UniProtKB", "url": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "521943", "url": "https://www.ncbi.nlm.nih.gov/gene/521943", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521943", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521943", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMDVQTD", "url": "https://omabrowser.org/oma/group/MMDVQTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXM9", "url": "https://www.orthodb.org/?gene=G3MXM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002685658", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685658", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXM9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMQSYYAKLLGELNEQRQRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSDAFSTILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAAHQMDSGSPKKGTAGETKSLVSRAEGEESEDRPREPPSGDLRGCCPLELVGKDSQGSGWVDSDRSTRPEQMEPKVELGAAEVEVDGQLQPPATPLSLAHREEGLPSSQAIDLAYSNYHVKQFLEALLRNSAVQSKEDVDHHFSQSLEGRPGGAGVAAMSSTMDVQTDWYGEDSGDVLVVPIKLHKCPFCPYSAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSPGLRRFGLCDSCTCITDTHDDDDELMPINLSLVEASFESQEKSDTDSDWPIYVESGEENDPAGEDSDDRPQIQPNLSGGDTLT", "length": 491, "header": "tr|G3MXM9-1|G3MXM9_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 8B OS=Bos taurus OX=9913 GN=ZBTB8B PE=4 SV=2 CANONICAL=G3MXM9-1" }, "isoforms": [ { "isoform_ac": "G3MXM9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXM9/entry", "sequence": { "sequence": "MEMQSYYAKLLGELNEQRQRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSDAFSTILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAAHQMDSGSPKKGTAGETKSLVSRAEGEESEDRPREPPSGDLRGCCPLELVGKDSQGSGWVDSDRSTRPEQMEPKVELGAAEVEVDGQLQPPATPLSLAHREEGLPSSQAIDLAYSNYHVKQFLEALLRNSAVQSKEDVDHHFSQSLEGRPGGAGVAAMSSTMDVQTDWYGEDSGDVLVVPIKLHKCPFCPYSAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSPGLRRFGLCDSCTCITDTHDDDDELMPINLSLVEASFESQEKSDTDSDWPIYVESGEENDPAGEDSDDRPQIQPNLSGGDTLT", "length": 491, "header": "tr|G3MXM9-1|G3MXM9_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 8B OS=Bos taurus OX=9913 GN=ZBTB8B PE=4 SV=2 CANONICAL=G3MXM9-1" }, "locus": { "chromosome": "2", "start_pos": 121145458, "end_pos": 121130306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065553.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065553.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054297.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054297.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521943", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521943", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZLP0-1", "protein_name": "Zinc finger and BTB domain-containing protein 8B", "gene_name": "Zbtb8b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGGVSVRSARWRRLEPGARAPGPSRAAAAGGEMEAQSYSAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSDAFSTILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLDICRKMEKEAAVAAAVAVAAAAAAAHQIDSESPSSVLEGTSCGTKSFVSSPVNGEGSLDCTRSSCDDCHPLELVAKDSQGSGASEGDLCIVPRRVEPKVEFDVARVEVETEEQLQQYAAPLAHAEEVLPSNQALDLTYSSYHVKQFLEALLRNGAVQSRDDVDHPFSRGLEGRLEGPGVAVNSVMDVQNDWYREDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSSRPIICKGCRRTFTSHLSQGLRRFGLCDSCTCVTDPHDDDDDLMPVNLSLVEASSESHEKSDTDDWPIYIESGEENDPAAEDSDDKPYIRPNLAAPEMLT", "length": 515 }, "evidence": [ { "id": "G3MXM9", "url": "https://omabrowser.org/oma/group/G3MXM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CII0-1", "protein_name": "Zinc finger and BTB domain-containing protein 8B", "gene_name": "Zbtb8b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAQSYCAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLLHYIQDSGRHSTASLDIVTSDAFSTILDFLYSGKLDLCGENVIEVMSAASYLQMNEVVNFCKTYIRSSLDICRKMEKEAAVAAAMAAAAAAAAAAAHQIDSESPSSGLEGTSCGTKSFVSSPVDGEGSLDCTISSCDDCHPLELVAKDSQGSGVSDNDLCVVPRRVEPKVEFDVARVEVEADEQLQQYAAPLAHMEEGLPSNQALDLTYSSYHVKQFLEALLRNGAVQSKDDLDCHSSRGLEGRLEGPGVAMSSVMDVQNDWYREDAGDVLVVPIKLHRCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSSRPIICKGCRRTFTSHLSQGLRRFGLCDSCTCVTDPQEEEDDLMPVNLSLVEASSESHEKSDTDDWPIYIESGEENDPTAEDSDDKPHIRPNLPAPETLT", "length": 484 }, "evidence": [ { "id": "G3MXM9", "url": "https://omabrowser.org/oma/group/G3MXM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NAP8-1", "protein_name": "Zinc finger and BTB domain-containing protein 8B", "gene_name": "ZBTB8B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPAEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEVDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDDKPQIQPNLSDRETLT", "length": 495 }, "evidence": [ { "id": "G3MXM9", "url": "https://omabrowser.org/oma/group/G3MXM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MXM9", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 491, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXM9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXM9" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 92, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXM9", "database": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXN1-1", "uniprot_ac": "G3MXN1", "uniprot_id": "G3MXN1_BOVIN", "mass": { "chemical_mass": 24830.0, "monoisotopic_mass": 24830.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ferritin", "type": "recommended", "evidence": [ { "id": "G3MXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.", "evidence": [ { "database": "UniProtKB", "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1#function" }, { "database": "UniProtKB", "id": "RU361145", "url": "https://www.uniprot.org/uniprotkb/RU361145#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3MXN1", "locus": {} } ], "crossref": [ { "id": "G3MXN1", "url": "https://alphafold.ebi.ac.uk/entry/G3MXN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048419", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431:SF97", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431:SF97", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXN1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRLRGGRWRSRPRRCQPRAPADRAVIPWALEPPAMMPIPPSQVRQNYRLECEAALNSHAALEFHASFQCLALAFYLDRDDVALKHFHRFFLLRSHEHSKTAESLMFLQNRRGGRVSFLDIRKPETQQWESALQAMQDTLHLEKCVNQSLLDLHKLATDSSDAHLCDFLETGYLDQQVKFIKELGDHVSKLSNVGSPEGSLAGYFSDKLTLGDGDKED", "length": 218, "header": "tr|G3MXN1-1|G3MXN1_BOVIN Isoform 1 of Ferritin OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3MXN1-1" }, "isoforms": [ { "isoform_ac": "G3MXN1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1/entry", "sequence": { "sequence": "MGRLRGGRWRSRPRRCQPRAPADRAVIPWALEPPAMMPIPPSQVRQNYRLECEAALNSHAALEFHASFQCLALAFYLDRDDVALKHFHRFFLLRSHEHSKTAESLMFLQNRRGGRVSFLDIRKPETQQWESALQAMQDTLHLEKCVNQSLLDLHKLATDSSDAHLCDFLETGYLDQQVKFIKELGDHVSKLSNVGSPEGSLAGYFSDKLTLGDGDKED", "length": 218, "header": "tr|G3MXN1-1|G3MXN1_BOVIN Isoform 1 of Ferritin OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3MXN1-1" }, "locus": { "chromosome": "X", "start_pos": 106346234, "end_pos": 106345581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065561.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065561.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054299.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054299.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" } ], "pmid": "" }, { "name": "ferric iron binding", "id": "GO:0008199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008199", "evidence": [ { "database": "UniProtKB", "id": "G3MXN1", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXN1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 218, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXN1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXN1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" }, { "id": "PS50905", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50905" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ferritin-like diiron", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 195, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "G3MXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 143, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 143, "end_pos": 143, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 177, "amino_acid": "Gln", "chebi_lig_id": "CHEBI:24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 177, "end_pos": 177, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN1" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 63, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 63, "end_pos": 63, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXN4-1", "uniprot_ac": "G3MXN4", "uniprot_id": "G3MXN4_BOVIN", "mass": { "chemical_mass": 126376.0, "monoisotopic_mass": 126376.0 }, "refseq": { "ac": "XP_024849614", "name": "nuclear receptor-interacting protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849614" }, "gene_names": [ { "name": "NRIP1", "type": "recommended", "evidence": [ { "id": "G3MXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ] }, { "name": "NRIP1", "type": "synonym", "evidence": [ { "id": "XP_024849614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849614" } ] } ], "protein_names": [ { "name": "Nuclear receptor interacting protein 1", "type": "synonym", "evidence": [ { "id": "G3MXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN4/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor-interacting protein 1", "type": "synonym", "evidence": [ { "id": "XP_024849614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849614" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NRIP1", "url": "https://www.uniprot.org/uniprotkb/G3MXN4", "locus": { "chromosome": "1", "start_pos": 22198047, "end_pos": 22089288, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047293", "url": "https://www.ensembl.org/id/ENSBTAG00000047293" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047293", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047293", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524960", "url": "https://www.ncbi.nlm.nih.gov/gene/524960", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524960", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524960", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPPYACG", "url": "https://omabrowser.org/oma/group/SPPYACG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXN4", "url": "https://www.orthodb.org/?gene=G3MXN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15088:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15088:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15688", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15688", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15689", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15689", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9018519", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9018519", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024849614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXN4-1", "url": "https://www.uniprot.org/uniprotkb/G3MXN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAEGSGTAVDKASAGRNEDDQNFNISGSAFPTCQRNGPVLSTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMADSAPKGKQDSKVLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHNSLKVEKDLRCYGVASSHLKTLLKKSKAKDQKPDTSIPDVTKTLIRDRFIESPHHVGQSGTKVVSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQKDMGSFQLSKGISGHLNGQARTSSNKLMASKSTAFQNPVGIVPSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDDYSDPNPSFTDESSGDESSYSNCVPIDLSCKHRIEKPEPDQPVSLDNLTQSLLNTWDPKVPEVDVKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENMERNGSPQEAHSDETKFSTQNYTRTSVIESPSTNRTTPVSTPPLLASTKADSPINLSQHSLVIKWNSPPYACGPQPEKPANTASNHLMDLTKSKESQGEKAIHNEGAQNSATFSASKLLQNLAQCGMQSSVSGEEQRPSKQLLSVNTDKPPGMIDRLNSPLLANKTSAVEEKKAFGSHTIGPEPGLSGSEIENLLERRTVLQLLLGNPNKGKTEKKEKMPLRDESTQEHTDRALSEQILMVKIKSEPCDDLHPHATGTHLSHEAPGAPFLGMAPPMQRSAPALPTSEDLKPEPGSPQDFSFSKNGLLSRLLRQNQDSHLADELDSSHRNSELTLVESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANSHSAPEVLYGSLLNQQELKLSRSDLEFKHPASHGSASESEPRNWTRESKSFNVLKQLLLSENCVRDLSQHRSNSVADSKKKGHRNSVTNSKPEFSIASLNGLMCGATQPGSCMVSRTFPYPGVGKAPRSPPFPEHLGCTGSRPEAGLVNGCSMPSEKGPIKWVITDVDKNEYEKDSPRLTKTNPILYYMLQKGGSSVTSRETQDRDIWREPSSAESISQVTIKEELLPPAETKASFFNLRSTYNSHMGNNASRPHSANGEVYGLLGNMLTIKKESE", "length": 1156, "header": "tr|G3MXN4-1|G3MXN4_BOVIN Isoform 1 of Nuclear receptor interacting protein 1 OS=Bos taurus OX=9913 GN=NRIP1 PE=4 SV=2 CANONICAL=G3MXN4-1" }, "isoforms": [ { "isoform_ac": "G3MXN4-1", "url": "https://www.uniprot.org/uniprotkb/G3MXN4/entry", "sequence": { "sequence": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAEGSGTAVDKASAGRNEDDQNFNISGSAFPTCQRNGPVLSTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMADSAPKGKQDSKVLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHNSLKVEKDLRCYGVASSHLKTLLKKSKAKDQKPDTSIPDVTKTLIRDRFIESPHHVGQSGTKVVSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQKDMGSFQLSKGISGHLNGQARTSSNKLMASKSTAFQNPVGIVPSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDDYSDPNPSFTDESSGDESSYSNCVPIDLSCKHRIEKPEPDQPVSLDNLTQSLLNTWDPKVPEVDVKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENMERNGSPQEAHSDETKFSTQNYTRTSVIESPSTNRTTPVSTPPLLASTKADSPINLSQHSLVIKWNSPPYACGPQPEKPANTASNHLMDLTKSKESQGEKAIHNEGAQNSATFSASKLLQNLAQCGMQSSVSGEEQRPSKQLLSVNTDKPPGMIDRLNSPLLANKTSAVEEKKAFGSHTIGPEPGLSGSEIENLLERRTVLQLLLGNPNKGKTEKKEKMPLRDESTQEHTDRALSEQILMVKIKSEPCDDLHPHATGTHLSHEAPGAPFLGMAPPMQRSAPALPTSEDLKPEPGSPQDFSFSKNGLLSRLLRQNQDSHLADELDSSHRNSELTLVESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANSHSAPEVLYGSLLNQQELKLSRSDLEFKHPASHGSASESEPRNWTRESKSFNVLKQLLLSENCVRDLSQHRSNSVADSKKKGHRNSVTNSKPEFSIASLNGLMCGATQPGSCMVSRTFPYPGVGKAPRSPPFPEHLGCTGSRPEAGLVNGCSMPSEKGPIKWVITDVDKNEYEKDSPRLTKTNPILYYMLQKGGSSVTSRETQDRDIWREPSSAESISQVTIKEELLPPAETKASFFNLRSTYNSHMGNNASRPHSANGEVYGLLGNMLTIKKESE", "length": 1156, "header": "tr|G3MXN4-1|G3MXN4_BOVIN Isoform 1 of Nuclear receptor interacting protein 1 OS=Bos taurus OX=9913 GN=NRIP1 PE=4 SV=2 CANONICAL=G3MXN4-1" }, "locus": { "chromosome": "1", "start_pos": 22193282, "end_pos": 22189815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101458.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101458.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096176.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096176.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:524960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524960", "resource": "KEGG Pathway" }, { "id": "R-BTA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-BTA-9018519", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9018519", "resource": "Reactome", "description": "Estrogen-dependent gene expression" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V672-1", "protein_name": "Nuclear receptor interacting protein 1", "gene_name": "Nrip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTHGEELGSDVHPDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHSEEDQNFNLSGSAFPTCQSNGPTLSTQTYQGSGMLHLKKARLLQSSEDWNAAQRKRLSDSIVNLNVKKEALLVGMVDSVPKGKQDSTVLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHESLKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGTTLPDVTPNLIRDSFVESSPHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAHLQQYSREHALKTQSAHQAASERLAAMARLQENGQKDMSSFQLSKGVSGHLDGQARTLPQSSKLAASKNNAAVFQNPMCGVPSSPKNTSYKNSLERNNIKQAANNSLLLHLLKSQTIPTPMNGHSQHERGSSFESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKPETERPVSLENLTQSLLNTWDPKVPGVDIKEDQDTSTNSKLNSHQKVTLLQLLLGHKTEESVERNASPQEVHSDVTKFSPQNYTRTSVIESPSTNRTTPVSTPPLHTSSQGESPINLSQHSLVIKWNSPPYACSTPASKLTNTVTGHLMDLTKGKESQAEKPAPSEGAQNSATFSASKLLQNLAQCGMQSSVPGEEQRPSKQLLSGHTDKPLGLIDRLNSPLLSNKANAAEENKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSNKGKSEKKERAPALDEARQEHSERPGNEQILMVKIKSEPCDDFQTHNTNVHLNHDAKSTPFLGGTPTIQRSSAALPVSEDLKSEPASPQDFSFSKNGLLSRLLRQNQESYPADDQDKSHRNSELTPLESKNFCMVPKKRKLYTEPLENPFKKMKNSAVDNANNHGGPEVLYGSLLNQEELKFSRNDLDYKYSAGHSSASDGEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVTDNKKKGHKNNVPNSKPEFSISSLNGLMYGSPQPGSCVDHRTFSYPGMVKTPLSSPFPEHLGCVGSRPEPGLLNGCSVPVPGEKGPIKWVITDVEKNEYEKDSPRLTKTNPILYYMLQKGGNSVTTQETQDKDIWGEPSSAESLSQVTVKEEMLPAAETKAAFFNLRSPYNSHMGNNASRPHSTNGEAYGPLGNVLTIKKECE", "length": 1162 }, "evidence": [ { "id": "G3MXN4", "url": "https://omabrowser.org/oma/group/G3MXN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LP18-1", "protein_name": "Nuclear receptor interacting protein 1", "gene_name": "NRIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAEGSGTAVDKKSAGRNEEDQNFNISGNAFPTCQSNGPVLNTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMVDNVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHDSLKVEKDLRCYGVASSHLKTLLKKSKAKDQKPDTNLPDVTKNLIRERFVESPHHVGQSGTKVLSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQKDVGSFQVSKGVSGHLNGQARTSSNKLMASKSTTFQSPMGLVPSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDDYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKPEPDQPVSLDNLTQSLLNTWDPKVPEVDNKEDQDTSKNSRLNSHQKVTLLQLLLGHKNEENVERNNSPQEVHSDVTKFSTQNYARTSVIESPGTNRTTPVSTPPLLASAKAESPINLSQHSLVIRWNSPPYACGPPSEKPTNATSNRLMDLTKSKDLQGEKPVQNEGAQNSATFSASKLLKNLAQCGMQSSMSGEEQRPSKQLLSVNTDKPTGVMERLGSPLLANKTNPAEENKAFGSHSAGPEPGLSGSEIENLLERRTVLQLLLGNSNKGKMEKKEKIPLREGSTQEHTDRALSEQILMVKIKSEPCDDFHAHTPDVHSSPDAQGAPFLGMAPPVQRGAAALPAPEDLKSEPASPQDFSFSKNGLLSRLLRQNQESYPADDLDGSHRNSELTLLESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAAGSHSAPEVLYGSLLNQQELKLSRNELDLKYPGSHSSPSESEHRSWARESKSFNVLKQLLLSENCVRDLSQHRSNSVGDSKKKGCKNSVTNSKPEFSISSLNGLMYSAAQPSSCMDSRTFPYPGGVKTPLSPPFPEHLGCTGSRPESGLVNGCSMPSEKRPIKWVITDAEKNEYEKDSPRLTKTNPILYYMLQKGGNSVTSRETQDKDVWREPSSAENISQVTIKEELLPAAETKASFFNLRSPYNSHMGNNASRPHSANGEVYGLLGNMLTIKKESE", "length": 1156 }, "evidence": [ { "id": "G3MXN4", "url": "https://omabrowser.org/oma/group/G3MXN4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHNEEDQNFNISGSAFPTCQSNGPVLNTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIMNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHDSLKVEKDLRCYGVASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAESPHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTDKPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEIENLLERRTVLQLLLGNPNKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAPFLGMAPAVQRSAPALPVSEDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHRNNEMALLESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANNHSAPEVLYGSLLNQEELKFSRNDLEFKYPAGHGSASESEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVADSKKKGHKNNVTNSKPEFSISSLNGLMYSSTQPSSCMDNRTFSYPGVVKTPVSPTFPEHLGCAGSRPESGLLNGCSMPSEKGPIKWVITDAEKNEYEKDSPRLTKTNPILYYMLQKGGNSVTSRETQDKDIWREASSAESVSQVTAKEELLPTAETKASFFNLRSPYNSHMGNNASRPHSANGEVYGLLGSVLTIKKESE", "length": 1158 }, "evidence": [ { "id": "G3MXN4", "url": "https://omabrowser.org/oma/group/G3MXN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CBD1-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "Nrip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAINKKSAGHKEEDQNFNLSGSAFPSCQSNGPTVSTQTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHESLKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGPTLPDVTPNLIRDSFVESSHPAVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQLALLLSSEAHLQQYSREHALKTQNAHQVASERLAAMARLQENGQKDVGSSQLSKGVSGHLNGQARALPASKLVANKNNAATFQSPMGVVPSSPKNTSYKNSLERNNLKQAANNSLLLHLLKSQTIPTPMNGHSQNERASSFESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRIEKPEAERPVSLENLTQSLLNTWDPKIPGVDIKEDQDTSTNSKLNSHQKVTLLQLLLGHKSEETVERNASPQDIHSDGTKFSPQNYTRTSVIESPSTNRTTPVSTPPLYTASQAESPINLSQHSLVIKWNSPPYACSTPASKLTNTAPSHLMDLTKGKESQAEKPAPSEGAQNSATFSASKLLQNLAQCGLQSSGPGEEQRPCKQLLSGNPDKPLGLIDRLNSPLLSNKTNAAEESKAFSSQPAGPEPGLPGCEIENLLERRTVLQLLLGNSSKGKNEKKEKTPARDEAPQEHSERAANEQILMVKIKSEPCDDFQTHNTNLPLNHDAKSAPFLGVTPAIHRSTAALPVSEDFKSEPASPQDFSFSKNGLLSRLLRQNQESYPADEQDKSHRNSELPTLESKNICMVPKKRKLYTEPLENPFKKMKNTAVDTANHHSGPEVLYGSLLHQEELKFSRNELDYKYPAGHSSASDGDHRSWARESKSFNVLKQLLLSENCVRDLSPHRSDSVPDTKKKGHKNNAPGSKPEFGISSLNGLMYSSPQPGSCVTDHRTFSYPGMVKTPLSPPFPEHLGCVGSRPEPGLLNGCSVPGEKGPIKWVIADMDKNEYEKDSPRLTKTNPILYYMLQKGGGNSVTTQETQDKDIWREPASAESLSQVTVKEELLPAAETKASFFNLRSPYNSHMGNNASRPHSTNGEVYGLLGNALTIKKESE", "length": 1161 }, "evidence": [ { "id": "G3MXN4", "url": "https://omabrowser.org/oma/group/G3MXN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "R4GIS3-1", "protein_name": "Nuclear receptor interacting protein 1", "gene_name": "NRIP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTHGEELGSEMHQDSVVLTYLEGLLMHQAAGGSGTAVDKKSTGHSGEDQNFNISGNIFPSCQSNGPVLNTSTYQGSGMLHLKKARLLQSSEDWNAAKRRRLSDSIVDLDGKKEALLAGMVENVPKGKQDSTLLASLLQSFSSRLQSVALSQQIRQSLKEQGYSLSHDSLQVEKDLRCYGVASSHLKTLLKKSKAKDQKLDNSLPDITKNLPKERFIESPHAVQSGPKVINEPLSCAARLQAVASMVEKRSSPAASPKPSVACSQLALLLSSEAHLQQYSREHALKAQNANQIASERLAAMARLQESAQKDIGQFSLAKGMTSHLNGQAGSSTKMVSSKSNMTPFQSSVGITHSPPKNVGFKSTLERNNVKTSPSNSLLLHLLKSQNTTKQLKGHEQSERASIFEESSTPTTIDEYSDNNPSFTDDSSDDESSHSNCLPIDLSFKQRTDKPDTGPPASLDNLTQSLLHSWDPKVSCPENKEDKDTPKASKLNPHQKVTLLQLLLGHKSEEKVDKSNEPQGPHSAADVAKFTVQTGKRTPVTDSPNANRMTPLNTPPLLASAKADSPINLSHPSLAIKRSSPPYACSIQPDRLVNPASKHLIDLSKSKEIQGAKLSRNDSPQNSSAFSASKLLQNLAQCGMQTSMSSEEQRSGKHLLVGSTDKPVGLIDRLNSPLLTNKLSTHEENNKILSCQSVPTEQGLPGSEIENLLERRTVLQLLLGTPNKGKNEKKERVLLRDESSQEQTDKALNEQILTVKIKTEPSEESNVPYNSNAQQIRECKGNKFQGFVHSLQRNTAASPASEEMKSEPHSPQDFSFSKNGLLSRLLRQNQDSYPADELDRSHQNNEPTHLESKSLCTIPKKRKLHAEPLESPLKKMKTNVSHAANNHISPSEALYGPLLSQQELKFGRSDSEFKYAVSHGSNNESGNRSWSRDSKGFNVLKQLLLSENCERDLSQHRNNLLTEGKKKGNKSNATINKPEFSISSVNALMGSPVQQSGCVDHRTFQYPVKSPASSPFPEHLGRLEPDQFSVCPMPSEKGPIRWVITGMDKNDYEKDSPRLTKTNPILYYMLQKGGNSVSSQEAHDKEIWNEPSFTDSSTRVTIKEELTSDGELKTPFSNLRSPYSSHMGNKTSHQHAVNGEVHGLLEKVLTIKKEPE", "length": 1155 }, "evidence": [ { "id": "G3MXN4", "url": "https://omabrowser.org/oma/group/G3MXN4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "ovarian follicle rupture", "id": "GO:0001543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001543", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "cellular response to estradiol stimulus", "id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "nuclear glucocorticoid receptor binding", "id": "GO:0035259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035259", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "nuclear retinoid X receptor binding", "id": "GO:0046965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046965", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "G3MXN4", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 923, "end_pos": 925, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXN4" }, { "id": "PF15687", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15687" }, { "id": "PF15688", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15688" }, { "id": "PF15690", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15690" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear receptor-interacting protein 1 repression", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 330, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1130, "end_pos": 1132 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 923, "end_pos": 925 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXP7-1", "uniprot_ac": "G3MXP7", "uniprot_id": "G3MXP7_BOVIN", "mass": { "chemical_mass": 34534.0, "monoisotopic_mass": 34534.0 }, "refseq": {}, "gene_names": [ { "name": "OR8B60", "type": "recommended", "evidence": [ { "id": "G3MXP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXP7" } ] } ], "protein_names": [ { "name": "Olfactory receptor", 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"strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000053225", "url": "https://www.ensembl.org/id/ENSBTAG00000053225" } ] } } ], "crossref": [ { "id": "G3MXP7", "url": "https://alphafold.ebi.ac.uk/entry/G3MXP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MXP7", "url": "https://www.orthodb.org/?gene=G3MXP7", "database": "OrthoDB", "categories": [ "Protein 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377629" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MXS4", "url": "https://www.uniprot.org/uniprotkb/G3MXS4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXS4", "url": "https://www.uniprot.org/uniprotkb/G3MXS4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8J17", "url": "https://www.uniprot.org/uniprotkb/G3MXS4", "locus": { "chromosome": "15", "start_pos": 79608802, "end_pos": 79607876, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000059758", "url": "https://www.ensembl.org/id/ENSBTAG00000059758" } ] } } ], "crossref": [ { "id": "G3MXS4", "url": "https://alphafold.ebi.ac.uk/entry/G3MXS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100336901", "url": "https://www.ncbi.nlm.nih.gov/gene/100336901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336901", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { 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"https://www.orthodb.org/?gene=G3MXT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10129:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10129:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059730327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059730327", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXT0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTSGGAGGGGGAAQAGATPGQASGGPGAVGGASGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHAGHHGAHHPAAAAAYEAFRGQGFAGGGGADDMGAGHHHGTHHAAHHHHHAPHHHHHHHHGGAGHGGGGTTHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPRESSPPQAGPGGAKGAPDFFL", "length": 351, "header": "tr|G3MXT0-1|G3MXT0_BOVIN Isoform 1 of MAF bZIP transcription factor A OS=Bos taurus OX=9913 GN=MAFA PE=4 SV=1 CANONICAL=G3MXT0-1" }, "isoforms": [ { "isoform_ac": "G3MXT0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXT0/entry", "sequence": { "sequence": "MATELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTSGGAGGGGGAAQAGATPGQASGGPGAVGGASGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHAGHHGAHHPAAAAAYEAFRGQGFAGGGGADDMGAGHHHGTHHAAHHHHHAPHHHHHHHHGGAGHGGGGTTHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPRESSPPQAGPGGAKGAPDFFL", "length": 351, "header": "tr|G3MXT0-1|G3MXT0_BOVIN Isoform 1 of MAF bZIP transcription factor A OS=Bos taurus OX=9913 GN=MAFA PE=4 SV=1 CANONICAL=G3MXT0-1" }, "locus": { "chromosome": "14", "start_pos": 1226099, "end_pos": 1225047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037397.5", "url": "https://www.ensembl.org/id/ENSBTAT00000037397.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054350.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054350.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:618421", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618421", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KMR8-1", "protein_name": "Transcription factor MafAa", "gene_name": "mafaa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATDLAMSAELPNSPLAIEYVNDFDLMKFEIKKEPPEADRYCHRLPPGSLSSTPISTPCSSVPSSPSFCAPSPGSQPGQNLVNGVNNNNNNSGNGNNNTQGSSGKPQMEDLYWIPNYQHHISPEALNLTPEDAVEALIGNAHHHHHHHHHQPYEGFRGQQYVGEDLSAATNGHHHPVHHHHHHHGHHAHARLEDRFSDEQLVSMTVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRYKRVQQRHMLESEKCTLQSQVEQLKQDVARLIKERDLYKEKYEKLASRAFNGGGNTRDPSSGNHVKTTSTDFFM", "length": 315 }, "evidence": [ { "id": "G3MXT0", "url": "https://omabrowser.org/oma/group/G3MXT0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZNT6-1", "protein_name": "Transcription factor MafA", "gene_name": "Mafa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGSSAGGGGSAAQAGGAPGPPSGGPGTVGGASGKAVLEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHSAHHGAHHPAAAAAYEAFRGQSFAGGGGGGADDMGAGHHHGAHHTAHHHHSAHHHHHHHHHHGGSGHHGGGAGHGGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPREPSPAQAGPGAAKGAPDFFL", "length": 361 }, "evidence": [ { "id": "G3MXT0", "url": "https://omabrowser.org/oma/group/G3MXT0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O42290-1", "protein_name": "Transcription factor MafA", "gene_name": "MAFA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASELAMTAELPTSPLAIEYVNDFDLMKFEVKKEPAEAERLCHRLPAGSLSSTPLSTPCSSVPSSPSFCAPSPGGQPSAGPTAAPLGSKPQLEELYWMSGYQHHLNPEALNLTPEDAVEALIGAPHHHHHHHQSYESFRPQPFGGEELPPAAHHHNAHHHHHHHHLRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQNRRTLKNRGYAQSCRYKRVQQRHILENEKCQLQSQVEQLKQEVSRLAKERDLYKEKYEKLAARGFPREPSPPAAPKTTAADFFM", "length": 286 }, "evidence": [ { "id": "G3MXT0", "url": "https://omabrowser.org/oma/group/G3MXT0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8CF90-1", "protein_name": "Transcription factor MafA", "gene_name": "Mafa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGAGGGGSAAQAGGAPGPPSGGPGTVGGASGKAVLEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGQSFAGGGGADDMGAGHHHGAHHTAHHHHSAHHHHHHHHHHGGSGHHGGGAGHGGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPREPSPAQAGPGAAKGAPDFFL", "length": 359 }, "evidence": [ { "id": "G3MXT0", "url": "https://omabrowser.org/oma/group/G3MXT0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NHW3-1", "protein_name": "Transcription factor MafA", "gene_name": "MAFA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL", "length": 353 }, "evidence": [ { "id": "G3MXT0", "url": "https://omabrowser.org/oma/group/G3MXT0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" }, { "name": "response to glucose", "id": "GO:0009749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" }, { "name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "G3MXT0", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXT0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 351, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXT0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXT0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXT0" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 252, "end_pos": 315, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 91 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXU9-1", "uniprot_ac": "G3MXU9", "uniprot_id": "G3MXU9_BOVIN", "mass": { "chemical_mass": 34686.0, "monoisotopic_mass": 34686.0 }, "refseq": { "ac": "NP_001376685", "name": "olfactory receptor family 4 subfamily N member 5", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376685" }, "gene_names": [ { "name": "OR4N5", "type": "recommended", "evidence": [ { "id": "G3MXU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXU9" } ] }, { "name": "OR4N5", "type": "synonym", "evidence": [ { "id": "NP_001376685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376685" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MXU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXU9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily N member 5", "type": "synonym", "evidence": [ { "id": "NP_001376685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376685" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376685" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MXU9", "url": "https://www.uniprot.org/uniprotkb/G3MXU9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXU9", "url": "https://www.uniprot.org/uniprotkb/G3MXU9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4N5", "url": "https://www.uniprot.org/uniprotkb/G3MXU9", "locus": { "chromosome": "10", "start_pos": 27489891, "end_pos": 27488962, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000065908", "url": "https://www.ensembl.org/id/ENSBTAG00000065908" } ] } } ], "crossref": [ { "id": "G3MXU9", "url": "https://alphafold.ebi.ac.uk/entry/G3MXU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048339", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048339", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505186", "url": "https://www.ncbi.nlm.nih.gov/gene/505186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505186", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MXU9", "url": "https://www.orthodb.org/?gene=G3MXU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376685", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXU9", "url": "https://www.uniprot.org/uniprotkb/G3MXU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXU9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMARENSTEVTEFILLGLTQSQDVQLLVFTLVLIFYLIILPGNFLIILTIRSDPSLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYKGCITQLFFLHFLGAGEMFLLVVMAFDRYIAICRPLHYSTVMNPRACYALLLALWLGGFTHSIVQVALIIHLPFCGPNRLDNFFCDVPQVIKLACADTFVVELLMVSNSGLLTLLCFLGLLASYAVILCRVKGHSSAGKSKALSTCTTHIIIVFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLMNPVIYTLRNQEIKASMRKLLSHHMVC", "length": 309, "header": "tr|G3MXU9-1|G3MXU9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4N5 PE=3 SV=2 CANONICAL=G3MXU9-1" }, "isoforms": [ { "isoform_ac": "G3MXU9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXU9/entry", "sequence": { "sequence": 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377571" }, "gene_names": [ { "name": "OR6C1Q", "type": "recommended", "evidence": [ { "id": "G3MXW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXW1" } ] }, { "name": "OR6C1Q", "type": "synonym", "evidence": [ { "id": "NP_001377571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377571" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MXW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXW1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 6 subfamily C member 1Q", "type": "synonym", "evidence": [ { "id": "NP_001377571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377571" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"MPHPLTGGPAPPTPLDTVGLVDQRLGDAGISGSASILEDRDMDPWALPQLKDTGQAWRDLSAAGRALRVLTGFLKACGLLGGLYLFICSLDILSSAFQLLGSKVTGDIFKDNVVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVASKLLTVRASVPIIMGVNVGTSITSTLVSMAQSGDRDEFRRAFGGSAVHGIFNWLTALVLLPLESAAAPLERLSALILGTASLQPGGHTPDILKVLTRPLTHLIVQLDADVLMGSATGNTTNRSLIKRWCGTREQTTAGNSSYCGAAAGGPCPGKNGSASEEPLPCRHLFAGTALADLAVGLILLAASLLVLCSCLVLIVKLLNSTLRGRVAQAVRTVINADFPRPFGWLSGYLAMLVGAGLTFALQSSSVFTAATVPLIGVGVISLERAYPLFLGSNTGTTTTALLAALASPSDMLLSAVQVALIHFFFNLAGILLWYVVPILRLPVPLAKYFGNLTASYRWVAVAYLLLCFLVLPLAAFGLSLAGGAVLAAVGAPLVVLVLLVALVTVLQRHRPAWLPRRLRSWAWLPLWLRSLEPWDLLVRRCCPCKACSPPQAVAKETHCYENPQVLASQQL", "length": 602, "header": "tr|G3MXY5-1|G3MXY5_BOVIN Isoform 1 of Solute carrier family 34 member 3 OS=Bos taurus OX=9913 GN=SLC34A3 PE=3 SV=2 CANONICAL=G3MXY5-1" }, "isoforms": [ { "isoform_ac": "G3MXY5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXY5/entry", "sequence": { "sequence": 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[provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376801" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MY52", "url": "https://www.uniprot.org/uniprotkb/G3MY52#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY52", "url": "https://www.uniprot.org/uniprotkb/G3MY52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4N2", "url": "https://www.uniprot.org/uniprotkb/G3MY52", "locus": { "chromosome": "10", "start_pos": 27225320, "end_pos": 27224397, "strand": "-", "evidence": 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377731" }, "gene_names": [ { "name": "OR4K55B", "type": "recommended", "evidence": [ { "id": "G3MY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY66" } ] }, { "name": "OR4K55B", "type": "synonym", "evidence": [ { "id": "NP_001377731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377731" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MY66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY66/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily K member 55B", "type": "synonym", "evidence": [ { "id": "NP_001377731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377731" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377731", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377731" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MY66", "url": "https://www.uniprot.org/uniprotkb/G3MY66#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY66", "url": "https://www.uniprot.org/uniprotkb/G3MY66" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4K55B", "url": "https://www.uniprot.org/uniprotkb/G3MY66", "locus": { "chromosome": "10", "start_pos": 27541255, "end_pos": 27540317, "strand": "-", 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"MDAGNLSVVSEFVLLGLCHSWTMQVLLLLMFFMLYLIIVFGNIAIIILIITDPHLHSPMYFLLANLSFVDMWLCSVTTPKMITDFVRENKTISFGGCMCQILFVHFFGGGEMVLLVVMAYDRYVAICKPLHYSTIMNLQKCIGLVLTSWTTGFVHAMSQMAVIVQLPFCGPREIDSFFCDIPLVIKLACIDSYNLGILMNADSGVPAMTCFIVLLISYSYILLTIRQSSKAGTSRALSTCTAHITVVVLFFGPCIFIYVWPLSITWVDKFLAVFYSVITPLLNPAIYTLRNKEIKTAIKRFRSYYIHHKGNI", "length": 312, "header": "tr|G3MY66-1|G3MY66_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4K55B PE=3 SV=2 CANONICAL=G3MY66-1" }, "locus": { "chromosome": "10", "start_pos": 27541252, "end_pos": 27540317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052198.3", "url": "https://www.ensembl.org/id/ENSBTAT00000052198.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054494.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054494.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:112448558", "name": "", "url": 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"MSIMDGGNQSLVSEFVLLGLAHSQNIQALLFMMFLMLYLLIVSGNIVIMVLITFDPHLHSPMYFLLANLSFVDMWLSSVTTPKMITDFFRENKTISFAGCMCQVFFAHCIAAGEMVLLVVMAYDRYVAICKPLHYFTIMNLKRCTGLVLTSWTIGIVHALSHLVVIVELPFCSPKEIDSFFCDMPLVIKLACMDSHNLDILMYADCGVVGVTCFILLLISYTYILITVHQSSKAGASKALSTCTAHITVVMIFFVPCIFIYVWPLNITWLDKFLAVFYSVFTPLLNPAIYTLRNKEMKNAMKRFINTYRDFQGKS", "length": 315 }, "evidence": [ { "id": "G3MY66", "url": "https://omabrowser.org/oma/group/G3MY66/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3MY66", "url": "https://www.uniprot.org/uniprotkb/G3MY66" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MY66", "url": "https://www.uniprot.org/uniprotkb/G3MY66" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MY66", "url": "https://www.uniprot.org/uniprotkb/G3MY66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G3MY66", "url": "https://www.uniprot.org/uniprotkb/G3MY66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], 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"name": "FLRT1", "type": "synonym", "evidence": [ { "id": "XP_005227270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227270" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat transmembrane protein FLRT1", "type": "recommended", "evidence": [ { "id": "G3MY74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY74/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat transmembrane protein FLRT1", "type": "synonym", "evidence": [ { "id": "XP_005227270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227270" } ] } ], "function": [ { "annotation": "Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases. Promotes neurite outgrowth via FGFR1-mediated activation of downstream MAP kinases. Promotes an increase both in neurite number and in neurite length. May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3.", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74#function" }, { "database": "UniProtKB", "id": "ARBA00058095", "url": "https://www.uniprot.org/uniprotkb/ARBA00058095#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FLRT1", "url": "https://www.uniprot.org/uniprotkb/G3MY74", "locus": { "chromosome": "29", "start_pos": 42444320, "end_pos": 42357942, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048264", "url": "https://www.ensembl.org/id/ENSBTAG00000048264" } ] } } ], "crossref": [ { "id": "ENSBTAG00000048264", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788007", "url": "https://www.ncbi.nlm.nih.gov/gene/788007", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:788007", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788007", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WLYDWLH", "url": "https://omabrowser.org/oma/group/WLYDWLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MY74", "url": "https://www.orthodb.org/?gene=G3MY74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5654687", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654687", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005227270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY74-1", "url": "https://www.uniprot.org/uniprotkb/G3MY74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVAHPTAAAATTATPATTVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPVNLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPRTLEELRLDDNRISTIPLHAFKGLSSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSARLQKLYLQDNAISHVPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLENLAQLLLRNNPWFCGCNLLWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEAGAQGGAVNAAAKTTHASDHASVTTPQGSLFTLKAKRPGLRLPDSSLDYPMATGDSAKTLAIHVKPLTADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMDTGNTYVADETPVCAKAETADSSGPATTLNQEQNADPMAGLPLAGIIGGAVALVFLFLVLGAICWYVHRASELLTRERAYNRGSRKKDDYLESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKGTHTIGYGTTRGYRDGGIPDIDYSYT", "length": 677, "header": "tr|G3MY74-1|G3MY74_BOVIN Isoform 1 of Leucine-rich repeat transmembrane protein FLRT1 OS=Bos taurus OX=9913 GN=FLRT1 PE=4 SV=1 CANONICAL=G3MY74-1" }, "isoforms": [ { "isoform_ac": "G3MY74-1", "url": "https://www.uniprot.org/uniprotkb/G3MY74/entry", "sequence": { "sequence": "MVVAHPTAAAATTATPATTVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPVNLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPRTLEELRLDDNRISTIPLHAFKGLSSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSARLQKLYLQDNAISHVPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLENLAQLLLRNNPWFCGCNLLWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEAGAQGGAVNAAAKTTHASDHASVTTPQGSLFTLKAKRPGLRLPDSSLDYPMATGDSAKTLAIHVKPLTADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMDTGNTYVADETPVCAKAETADSSGPATTLNQEQNADPMAGLPLAGIIGGAVALVFLFLVLGAICWYVHRASELLTRERAYNRGSRKKDDYLESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKGTHTIGYGTTRGYRDGGIPDIDYSYT", "length": 677, "header": "tr|G3MY74-1|G3MY74_BOVIN Isoform 1 of Leucine-rich repeat transmembrane protein FLRT1 OS=Bos taurus OX=9913 GN=FLRT1 PE=4 SV=1 CANONICAL=G3MY74-1" }, "locus": { "chromosome": "29", "start_pos": 42436168, "end_pos": 42434138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089410.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089410.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084590.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084590.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:788007", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788007", "resource": "KEGG Pathway" }, { "id": "R-BTA-5654687", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654687", "resource": "Reactome", "description": "Downstream signaling of activated FGFR1" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AC39-1", "protein_name": "Leucine-rich repeat transmembrane protein FLRT1", "gene_name": "Flrt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVAHPAATATTTPAATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPSDIPDDATTLYLQNNQINNAGIPQDLKTKVKVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEAGSQGSAANAAAKTTASNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMATGDGAKTLVIQVKPLTADSIRITWKAMLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETGNTYVADETPVCAKAETADSYGPTTTLNQEQNAGPMAGLPLAGIIGGAVALVFLFLVLGAICWYVHRAGELLTRERVYNRGSRKKDDYMESGTKKDNSILEIRGPGLQMLPINPYRSKEEYVVHTIFPSNGSSLCKGAHTIGYGTTRGYREGGIPDVDYSYT", "length": 674 }, "evidence": [ { "id": "G3MY74", "url": "https://omabrowser.org/oma/group/G3MY74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RPZ1-1", "protein_name": "Leucine-rich repeat transmembrane protein FLRT1", "gene_name": "FLRT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVVAHPTATATATPAATVTATVVMTTAAMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPVNLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPRTLEELRLDDNRISTIPLHAFKGLSRLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSARLQKLYLQDNAISHVPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLENLAQLLLRNNPWFCGCNLLWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEGGAQGGMANPAAKTTASDHASATTPQGSLFTLKAKRPGLRLPDSSLDYPMATGNGAKTLVIHVKPLTADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETGNTYVADETPVCAKAETADSYSPTTTLNQEQNADPMAGLPLAGIIGGAAALVFLFLVLGAICWYVHRASELLTRERAYNRGSRKKDDYVESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKGTHTIGYGTTRGYRDGGIPDIDYSYT", "length": 674 }, "evidence": [ { "id": "G3MY74", "url": "https://omabrowser.org/oma/group/G3MY74/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I875-1", "protein_name": "Leucine-rich repeat transmembrane protein FLRT1", "gene_name": "Flrt1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVVAHPTATTTTTPAATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPSDIPDDATTLYLQNNQINNAGIPQDLKTKVKVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEDDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEAGSQGSAANAAAKTTASNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMATGEGAKTLVIQVKPLTADSIRITWKAMLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETGNTYVADETPVCAKAETADSYGPTTTLNQEQNASPMAGLPLAGIIGGAVALVFLFLVLGAICWYVHRAGELLTRERVYNRGNRKKDDYMESGTKKDNSILEIRGPGLQMLPINPYRSKEEYVVHTIFPSNGSSLCKGAHPIGYGTTRGYRDGGIPDVDYSYT", "length": 674 }, "evidence": [ { "id": "G3MY74", "url": "https://omabrowser.org/oma/group/G3MY74/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6RKD8-2", "protein_name": "Leucine-rich repeat transmembrane protein FLRT1", "gene_name": "Flrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVAHSAATATTTPAATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPSDIPDDATTLYLQNNQINNAGIPQDLKTKVKVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVRARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEAGSQGGAANAAAKTTVSNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMATGDGAKTLVIQVKPLTADSIRITWKAMLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETGNTYVADETPVCAKAETADSYGPTTTLNQEQNAGPMAGLPLAGIIGGAVALVFLFLVLGAICWYVHRAGELLTRERVYNRGSRRKDDYMESGTKKDNSILEIRGPGLQMLPINPYRSKEEYVVHTIFPSNGSSLCKGAHTIGYGTTRGYREAGIPDVDYSYT", "length": 674 }, "evidence": [ { "id": "G3MY74", "url": "https://omabrowser.org/oma/group/G3MY74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZU1-2", "protein_name": "Leucine-rich repeat transmembrane protein FLRT1", "gene_name": "FLRT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVAHPTATATTTPTATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMATGDGAKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETADSYGPTTTLNQEQNAGPMASLPLAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRERAYNRGSRKKDDYMESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKATHTIGYGTTRGYRDGGIPDIDYSYT", "length": 674 }, "evidence": [ { "id": "G3MY74", "url": "https://omabrowser.org/oma/group/G3MY74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "neuronal cell body membrane", "id": "GO:0032809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032809", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "neuron projection extension", "id": "GO:1990138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990138", "evidence": [ { "database": "UniProtKB", "id": "G3MY74", "url": "https://www.uniprot.org/uniprotkb/G3MY74" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": 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Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers. Also plays a protective role against ER stress-induced apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "G3MY99", "url": "https://www.uniprot.org/uniprotkb/G3MY99#function" }, { "database": "UniProtKB", "id": "ARBA00059610", "url": "https://www.uniprot.org/uniprotkb/ARBA00059610#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY99", "url": "https://www.uniprot.org/uniprotkb/G3MY99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC107132228", "url": "https://www.uniprot.org/uniprotkb/G3MY99", "locus": {} } ], "crossref": [ { "id": "G3MY99", "url": "https://alphafold.ebi.ac.uk/entry/G3MY99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030592", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030592", 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"LLNQTLVTEFLLMGVTDIQELNPILFLTFLVMYFVNVFGNGSILMIVILDPRLHSPMYFFLGNLACVDICFSTVTVPKMLENFFSTSKAISFLGCITQLYLFHFLGSTEALLLTVMAFDRFVAICRPLHYPSIMNSHVCIQLTVVIWAIPFIPALLHSILTSQLSFCGSNHVHHFFCDVKPLLELACGNTELNRWLLNTFTGTVAIALFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHVMVVIIFYAPVLFIYINPDSRSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRIQL", "length": 308 }, "evidence": [ { "id": "G3MYA5", "url": "https://omabrowser.org/oma/group/G3MYA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58182-1", "protein_name": "Olfactory receptor 12D2", "gene_name": "OR12D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKPLRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVILFYAPVLFTYIHPALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL", "length": 307 }, "evidence": [ { "id": "G3MYA5", "url": "https://omabrowser.org/oma/group/G3MYA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920Z0-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNQTSVTEFLLLGVTDIQELNPILFVIFFTIYFINITGNGAILMIVILDPRLHSPMYFFLGNLACLDISYSTVTVPKLLQNLLSTSKAISFLGCITQLHFFHFLGSTETMLLPVMAFDRFVAICRPLHYSVIMNHQLCIHMTVTIWTLGFFHALLHSVMTSRLSFCGPNHVHHFFCDIKPLLDLACGNTELNLWLLNTVTGTIALTSFFLIFLSYFYIITNLLLKTRSCSMLHKALSTCASHFMVVVLFYAPVLFTYIRPASGSSLDQDTIIAIMYSVVTPALNPLIYTLRNKEVRSALNRKVRRWL", "length": 308 }, "evidence": [ { "id": "G3MYA5", "url": "https://omabrowser.org/oma/group/G3MYA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3MYA5", "url": "https://www.uniprot.org/uniprotkb/G3MYA5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MYA5", "url": "https://www.uniprot.org/uniprotkb/G3MYA5" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "G3MYA5", "url": "https://www.uniprot.org/uniprotkb/G3MYA5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MYA5", "url": "https://www.uniprot.org/uniprotkb/G3MYA5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MYA5", "url": "https://www.uniprot.org/uniprotkb/G3MYA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G3MYA5", "url": "https://www.uniprot.org/uniprotkb/G3MYA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYA5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 319, "overlap": "1.0", "method": "AlphaFold", 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}, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYD1-1", "uniprot_ac": "G3MYD1", "uniprot_id": "G3MYD1_BOVIN", "mass": { "chemical_mass": 48453.0, "monoisotopic_mass": 48453.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Transcriptional adapter", "type": "recommended", "evidence": [ { "id": "G3MYD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYD1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2.", "evidence": [ { "database": "UniProtKB", "id": "G3MYD1", "url": "https://www.uniprot.org/uniprotkb/G3MYD1#function" }, { "database": "UniProtKB", "id": "ARBA00057403", "url": "https://www.uniprot.org/uniprotkb/ARBA00057403#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], 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"Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055141", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055141", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12374", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12374", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12374:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12374:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22941", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22941", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MYD1", "url": "https://www.uniprot.org/uniprotkb/G3MYD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYD1-1", "url": "https://www.uniprot.org/uniprotkb/G3MYD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALSKKCCVYCLAEVSPLCFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDDGHFTLWGPEVEGGWTCREEQLLLDAIEQFGFGNWEDMAAHVGTSRTPQEVMEHYIIMYIHGNLGKACIPDSIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQPQLGYMLLRDEYDIEYDQDAETLITGLSVNYDEEDVEIELKRAHVDMYVRKLRERQRRKNIAQDYNLAPAFLGKDKKEEEWAAQRKVTKEEKELRLKLRPLYQLMSCKEFDDLFDTMYKEKMLRAKIRELQRYRHNGITKMQESVEYEVARHKREKCKENKAVAAAAAGGGKEDGRDGEFAAIEHLPGFELLSHREKVLCSSLNLSPVRYVTLKTIFIKDHLKKRQGIPSKSRLPSYLDKVLMKRILNFLTESGWISRDAS", "length": 422, "header": "tr|G3MYD1-1|G3MYD1_BOVIN Isoform 1 of Transcriptional adapter OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=G3MYD1-1" }, "isoforms": [ { "isoform_ac": "G3MYD1-1", "url": "https://www.uniprot.org/uniprotkb/G3MYD1/entry", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/G3MYE2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYE2", "url": "https://www.uniprot.org/uniprotkb/G3MYE2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3MYE2", "locus": {} } ], "crossref": [ { "id": "G3MYE2", "url": "https://alphafold.ebi.ac.uk/entry/G3MYE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005495", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005495", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00432", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00432", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23410:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23410:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MYE2", "url": "https://www.uniprot.org/uniprotkb/G3MYE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYE2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295, "header": "tr|G3MYE2-1|G3MYE2_BOVIN Isoform 1 of Large ribosomal subunit protein uL18 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3MYE2-1" }, "isoforms": [ { "isoform_ac": "G3MYE2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYE2/entry", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295, "header": "tr|G3MYE2-1|G3MYE2_BOVIN Isoform 1 of Large ribosomal subunit protein uL18 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3MYE2-1" }, "locus": { "chromosome": "8", "start_pos": 75861420, "end_pos": 75860536, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015661.6", "url": "https://www.ensembl.org/id/ENSBTAT00000015661.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054574.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054574.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "G3MYE2", "url": "https://omabrowser.org/oma/group/G3MYE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "G3MYE2", "url": "https://www.uniprot.org/uniprotkb/G3MYE2" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "G3MYE2", "url": "https://www.uniprot.org/uniprotkb/G3MYE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "5S rRNA binding", "id": "GO:0008097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008097", "evidence": [ { "database": "UniProtKB", "id": "G3MYE2", "url": "https://www.uniprot.org/uniprotkb/G3MYE2" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "G3MYE2", "url": "https://www.uniprot.org/uniprotkb/G3MYE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "G3MYE2", "url": "https://www.uniprot.org/uniprotkb/G3MYE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYE2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 295, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYE2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYE2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYE2" }, { "id": "PF14204", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14204" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL18 C-terminal eukaryotes", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 287, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"https://www.ncbi.nlm.nih.gov/gene/100300937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100300937", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010820442", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010820442", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MYF0", "url": "https://www.uniprot.org/uniprotkb/G3MYF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYF0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWAPEQKTIEPTLRDVRDRQVSRDGRGGRGCGWSHTSGRAESRASNYREPPLCFLIKSSMIGAVIGRGGSKIKDIQDSTSTKIQIVKGGPEAEVKIFGRKDMKAKAKAAIETLVKKQERTYSSECSVDSDASQALAERSWSRNNTTRATQPKDDTTKATQPRDYAAIVAKPRGYAAIVAQPGDDNAVRRAQPGDDMAREAQAEDDNTTRGDQPRETASRASQPRDEDADRDHAAREAQAKDNDITKEAQPRDYAAIVAQPRNYAAVVAQPRDYAAILAQPKDNATRRAQHGDHEARDPQVKDDDAARAAQSRDDNATKGVQPRDSIARETQSKDDTTTVAQPRDDDAIRGAQPRDPTARETQAKDDTTTVAQPRDDDATRGTEPRDHGAREAQAKDTRMAQPRDYAAIVAQPRDYAAIVAQPRAAQPKDVTARAAQPRIDWDQVKAGVVEWKKRKWADLPPIKKNLYIESKATHSLSEAQVEIWRKENFNIRCDDLTEGEKRPIPKPTCTFEDAFQQYPEIMQSIRRAGFQKPTPIQSQSWPIILQGIDLIGIAQTGTGKTLSYLMPGFIHIHSQPVSRKQRNGPGMLVLTPTRELALQVEAECSKYLYKGLKSVCIYGGGNRKGQIQDVTKGVDIIIATPGRLNDLQMNNFVNLRSITYLVLDEADKMLDLGFEHQIMKILLDVRPDRQTVMTTASWPDSTRRLAQSYLKQPMIVYVGTLDLVTVNTVKQNIIVTTEEEKRSLVKEFLQSLSPKDKVIVFVSRKLVADDLSSDLSIQGIPVQSLHGDREQSDRDQALEDFRTGRVKILIATDLAARGLDVSDVTHVYNYNFPRNIEEYVHRVGRTGRAGKIGESITLVTQDDWKIADELIKILQRANQIVPPSLRSMADRFKKRKQN", "length": 899, "header": "tr|G3MYF0-1|G3MYF0_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX53 PE=4 SV=4 CANONICAL=G3MYF0-1" }, "isoforms": [ { "isoform_ac": "G3MYF0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYF0/entry", "sequence": { "sequence": "MAWAPEQKTIEPTLRDVRDRQVSRDGRGGRGCGWSHTSGRAESRASNYREPPLCFLIKSSMIGAVIGRGGSKIKDIQDSTSTKIQIVKGGPEAEVKIFGRKDMKAKAKAAIETLVKKQERTYSSECSVDSDASQALAERSWSRNNTTRATQPKDDTTKATQPRDYAAIVAKPRGYAAIVAQPGDDNAVRRAQPGDDMAREAQAEDDNTTRGDQPRETASRASQPRDEDADRDHAAREAQAKDNDITKEAQPRDYAAIVAQPRNYAAVVAQPRDYAAILAQPKDNATRRAQHGDHEARDPQVKDDDAARAAQSRDDNATKGVQPRDSIARETQSKDDTTTVAQPRDDDAIRGAQPRDPTARETQAKDDTTTVAQPRDDDATRGTEPRDHGAREAQAKDTRMAQPRDYAAIVAQPRDYAAIVAQPRAAQPKDVTARAAQPRIDWDQVKAGVVEWKKRKWADLPPIKKNLYIESKATHSLSEAQVEIWRKENFNIRCDDLTEGEKRPIPKPTCTFEDAFQQYPEIMQSIRRAGFQKPTPIQSQSWPIILQGIDLIGIAQTGTGKTLSYLMPGFIHIHSQPVSRKQRNGPGMLVLTPTRELALQVEAECSKYLYKGLKSVCIYGGGNRKGQIQDVTKGVDIIIATPGRLNDLQMNNFVNLRSITYLVLDEADKMLDLGFEHQIMKILLDVRPDRQTVMTTASWPDSTRRLAQSYLKQPMIVYVGTLDLVTVNTVKQNIIVTTEEEKRSLVKEFLQSLSPKDKVIVFVSRKLVADDLSSDLSIQGIPVQSLHGDREQSDRDQALEDFRTGRVKILIATDLAARGLDVSDVTHVYNYNFPRNIEEYVHRVGRTGRAGKIGESITLVTQDDWKIADELIKILQRANQIVPPSLRSMADRFKKRKQN", "length": 899, "header": "tr|G3MYF0-1|G3MYF0_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX53 PE=4 SV=4 CANONICAL=G3MYF0-1" }, "locus": { "chromosome": "X", "start_pos": 120249839, "end_pos": 120247143, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065115.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065115.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054582.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054582.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100300937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300937", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "G3MYF0", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MYF0", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "G3MYF0", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "G3MYF0", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] } ] }, { "uniprot_ac": "A0A3Q1MS44", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MS44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS44" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MS44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS44" } ] } ] }, { "uniprot_ac": "A0A3Q1MU57", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] } ] }, { "uniprot_ac": "A0A3Q1NMG4", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] } ] }, { "uniprot_ac": "A0AAA9RUK3", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] } ] }, { "uniprot_ac": "A0AAA9RXI8", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] } ] }, { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] } ] }, { "uniprot_ac": "A0AAA9S5G9", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] } ] }, { "uniprot_ac": "A0AAA9S7V9", "gene_name": "RECQL4", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9SPF3", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] } ] }, { "uniprot_ac": "A0AAA9STQ6", "gene_name": "G3BP1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] } ] }, { "uniprot_ac": "A0AAA9SX42", "gene_name": "TDRD12", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] } ] }, { "uniprot_ac": "A0AAA9T2L7", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0AAA9T2L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2L7" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0AAA9T2L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2L7" } ] } ] }, { "uniprot_ac": "A0AAA9T674", "gene_name": "DDX56", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T674" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T674" } ] } ] }, { "uniprot_ac": "A0AAA9T8W7", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0AAA9T8W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8W7" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0AAA9T8W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8W7" } ] } ] }, { "uniprot_ac": "A0AAA9TGZ3", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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"activity": "", "evidence": [ { "id": "A0AAA9TT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT64" } ] } ] }, { "uniprot_ac": "A0AAA9U2H6", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9U2H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2H6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9U2H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9U2H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2H6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9U2H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLQ5", "gene_name": "MTREX", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6DLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLQ5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6DLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLQ5" } ] } ] }, { "uniprot_ac": "A0AAF6DLT1", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6DLT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6DLT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT1" } ] } ] }, { "uniprot_ac": "A0AAF6YME1", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0AAF6YME1", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0U5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6Z0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0U5" } ] } ] }, { "uniprot_ac": "A0AAF6Z733", "gene_name": "DHX9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6Z733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] } ] }, { "uniprot_ac": "A0ABI0NSA6", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NSA6", "database": 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{ "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ] } ] }, { "uniprot_ac": "A0ABI0P204", "gene_name": "LOC112446470", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] } ] }, { "uniprot_ac": "A4FUD9", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] } ] }, { "uniprot_ac": "A4K436", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A4K436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4K436" } ] } ] }, { "uniprot_ac": "A5D7C1", "gene_name": "DDX52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": 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"url": "https://www.uniprot.org/uniprotkb/Q5E9B5" } ] } ] }, { "uniprot_ac": "Q5E9H5", "gene_name": "BCS1L", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5E9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9H5" } ] } ] }, { "uniprot_ac": "Q5E9M9", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5E9M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9M9" } ] } ] }, { "uniprot_ac": "Q5E9N5", "gene_name": "CLPB", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5E9N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9N5" } ] } ] }, { "uniprot_ac": "Q5W5U4", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5W5U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5W5U4" } ] }, { "ec_number": 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"class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYF6-1", "uniprot_ac": "G3MYF6", "uniprot_id": "G3MYF6_BOVIN", "mass": { "chemical_mass": 37569.0, "monoisotopic_mass": 37569.0 }, "refseq": {}, "gene_names": [ { "name": "LOC618076", "type": "recommended", "evidence": [ { "id": "G3MYF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ] } ], "protein_names": [ { "name": "Acyltransferase", "type": "recommended", "evidence": [ { "id": "G3MYF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF6/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.-", "type": "synonym", "evidence": [ { "id": "G3MYF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC618076", "url": "https://www.uniprot.org/uniprotkb/G3MYF6", "locus": {} } ], "crossref": [ { "id": "G3MYF6", "url": "https://alphafold.ebi.ac.uk/entry/G3MYF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047808", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12317:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12317:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03982", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03982", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-75109", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75109", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYF6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTLKKQWLEVLSTYQYVLCFLFLGPFFSLVGFFLLFTSLWYLSVLYLVWLFLDWDTPQQGGRRNQWLKNCTVWKHLSDYFPIKLVKTVELPPDRNYVLLSHPHGIMGFGTVCNFSTEGTGCSQLFPGLRFSLAVLNCLLYVPGCREYIMSCGTCSVNRQSLDYVLSQPQLGRAVVIMVGGANEALHTVPGEHCLTLRNRKGFVRLALRHGASLVPVYSFGENDVFRVKAFAPDSWQRLFQVTIKRLLSFSPCIFWGRGLFSAKSWGLMPLARPITTVVGRPIPVPQCPQPTEEQVDHYHRLYMKALEQLFEEHKESCGLPASTHLTFI", "length": 329, "header": "tr|G3MYF6-1|G3MYF6_BOVIN Isoform 1 of Acyltransferase OS=Bos taurus OX=9913 GN=LOC618076 PE=3 SV=3 CANONICAL=G3MYF6-1" }, "isoforms": [ { "isoform_ac": "G3MYF6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYF6/entry", "sequence": { "sequence": "MKTLKKQWLEVLSTYQYVLCFLFLGPFFSLVGFFLLFTSLWYLSVLYLVWLFLDWDTPQQGGRRNQWLKNCTVWKHLSDYFPIKLVKTVELPPDRNYVLLSHPHGIMGFGTVCNFSTEGTGCSQLFPGLRFSLAVLNCLLYVPGCREYIMSCGTCSVNRQSLDYVLSQPQLGRAVVIMVGGANEALHTVPGEHCLTLRNRKGFVRLALRHGASLVPVYSFGENDVFRVKAFAPDSWQRLFQVTIKRLLSFSPCIFWGRGLFSAKSWGLMPLARPITTVVGRPIPVPQCPQPTEEQVDHYHRLYMKALEQLFEEHKESCGLPASTHLTFI", "length": 329, "header": "tr|G3MYF6-1|G3MYF6_BOVIN Isoform 1 of Acyltransferase OS=Bos taurus OX=9913 GN=LOC618076 PE=3 SV=3 CANONICAL=G3MYF6-1" }, "locus": { "chromosome": "25", "start_pos": 35511815, "end_pos": 35508890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064201.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064201.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054588.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054588.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-75109", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75109", "resource": "Reactome", "description": "Triglyceride biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum membrane", "id": "GO:1990578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990578", "evidence": [ { "database": "UniProtKB", "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ], "pmid": "" }, { "name": "monoacylglycerol biosynthetic process", "id": "GO:0006640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006640", "evidence": [ { "database": "UniProtKB", "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "diacylglycerol O-acyltransferase activity", "id": "GO:0004144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004144", "evidence": [ { "database": "UniProtKB", "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ], "pmid": "" }, { "name": "2-acylglycerol O-acyltransferase activity", "id": "GO:0003846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003846", "evidence": [ { "database": "UniProtKB", "id": "G3MYF6", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-6800334", "name": "MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-6800352" ], "output_participant_list": [], "enzyme_list": [ "Q70VZ7-1", "G3MYF6-1" ], "evidence": [ { "id": "R-BTA-6800334", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6800334" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6800352", "participant_name": "2AG [cytosol]", "crossref": [ { "id": "17389", "database": "ChEBI", "url": "" }, { "id": "C02112", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "G3MYF6", "gene_name": "LOC618076", "activity": [ { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "G3MYF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF6" } ] } ] }, { "uniprot_ac": "Q70VZ7", "gene_name": "MOGAT1", "activity": [ { "ec_number": "2.3.1.22", "activity": "a 2-acylglycerol + an acyl-CoA 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}, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MYH6", "url": "https://www.uniprot.org/uniprotkb/G3MYH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYH6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SRMSTNTSVVTEFILVGFSRLADLQGLLFSFFLTVYLLTVAGNLLIVLLVSADAALRTPMYFFLRNLSTLEIGYTSVTVPLLLHHLLTGQRHIPRSGCALQMFFFLLFGATECCLLAAMAYDRYAAICQPLRYPLLLSQRTCLCLAGSAWACGALVGLGHTSFVFSLPFCGPKAIPHFLCEIQAVLQLVCGNTSLNELQIILAAALLILCPFGLILGSYGRILATIFRIPSAAGRLKAFSTCSSHLVVVSLFYGTAIFIYIRPKASYDPTSDPLVSLFYAVVTPILNPIIYSLRNADVKAALKRTIQKIGPAGI", "length": 314, "header": "tr|G3MYH6-1|G3MYH6_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR10C1 PE=3 SV=3 CANONICAL=G3MYH6-1" }, "isoforms": [ { "isoform_ac": "G3MYH6-1", "url": 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chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G3MYH6", "url": "https://www.uniprot.org/uniprotkb/G3MYH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYH6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYH6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYH6" } ], 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"uniprot_ac": "G3MYH7", "uniprot_id": "G3MYH7_BOVIN", "mass": { "chemical_mass": 35157.0, "monoisotopic_mass": 35157.0 }, "refseq": { "ac": "NP_001377120", "name": "olfactory receptor family 10 subfamily AG member 63", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" }, "gene_names": [ { "name": "OR10AG63", "type": "recommended", "evidence": [ { "id": "G3MYH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYH7" } ] }, { "name": "OR10AG1", "type": "synonym", "evidence": [ { "id": "NP_001377120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" } ] }, { "name": "OR10AG63", "type": "synonym", "evidence": [ { "id": "NP_001377120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" } ] }, { "name": "OR10C1", "type": "synonym", "evidence": [ { "id": "NP_001377120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MYH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYH7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 10 subfamily AG member 63", "type": "synonym", "evidence": [ { "id": "NP_001377120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" } ] }, { "name": "olfactory receptor, family 10, subfamily AG, member 1", "type": "synonym", "evidence": [ { "id": "NP_001377120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" } ] }, { "name": "olfactory receptor, family 10, subfamily C, member 1", "type": "synonym", "evidence": [ { "id": "NP_001377120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MYH7", "url": "https://www.uniprot.org/uniprotkb/G3MYH7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYH7", "url": "https://www.uniprot.org/uniprotkb/G3MYH7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10AG63", "url": "https://www.uniprot.org/uniprotkb/G3MYH7", "locus": { "chromosome": "15", "start_pos": 78706970, "end_pos": 78707914, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048141", "url": "https://www.ensembl.org/id/ENSBTAG00000048141" } ] } } ], "crossref": [ { "id": "G3MYH7", "url": "https://alphafold.ebi.ac.uk/entry/G3MYH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048141", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048141", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614452", "url": "https://www.ncbi.nlm.nih.gov/gene/614452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614452", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614452", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TGMDKFL", "url": "https://omabrowser.org/oma/group/TGMDKFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYH7", "url": "https://www.orthodb.org/?gene=G3MYH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYH7", "url": "https://www.uniprot.org/uniprotkb/G3MYH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYH7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSRGQNPPQWNQTTLVDFILLGFSDIPDLQGFLFGVFLIMYMIILMGNSLIITITKMDPSLQTPMYFFLGNFSSLEICYVSVTVPRLLIDLCSQSRNISFLACAAQMYFFLVFGATECLLLTSMAYDRYVAICNPLLYPLLMNSRLCIQLAAGCWVSGVPVHIVLTYQIFSLPFCGSNQLNHFFCDIPPVLKLACGDTLITETLVYVIAVLVVTVPFMLILGSYVRIIETILKLPSATGRAKAFSTCSSHLMVVALFFGSGLITYLRPKSSHSKGMDKFLSLFYTIVTPMFNPMIYCLRNKDVMVALRKFLLK", "length": 314, "header": "tr|G3MYH7-1|G3MYH7_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR10AG63 PE=3 SV=2 CANONICAL=G3MYH7-1" }, "isoforms": [ { "isoform_ac": "G3MYH7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYH7/entry", "sequence": { "sequence": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYI7-1", "uniprot_ac": "G3MYI7", "uniprot_id": "G3MYI7_BOVIN", "mass": { "chemical_mass": 126502.0, "monoisotopic_mass": 126502.0 }, "refseq": { "ac": "XP_002696517", "name": "MAGE-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696517" }, "gene_names": [ { "name": "MAGEL2", "type": "recommended", "evidence": [ { "id": "G3MYI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYI7" } ] }, { "name": "MAGEL2", "type": "synonym", "evidence": [ { "id": "XP_002696517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696517" } ] } ], "protein_names": [ { "name": "MAGE family member L2", "type": "synonym", "evidence": [ { "id": "G3MYI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYI7/entry#names_and_taxonomy" } ] }, { "name": "MAGE-like protein 2", "type": "synonym", "evidence": [ { "id": "XP_002696517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696517" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYI7", "url": "https://www.uniprot.org/uniprotkb/G3MYI7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAGEL2", "url": "https://www.uniprot.org/uniprotkb/G3MYI7", "locus": { "chromosome": "21", "start_pos": 1204613, "end_pos": 1208780, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045998", "url": "https://www.ensembl.org/id/ENSBTAG00000045998" } ] } } ], "crossref": [ { "id": "G3MYI7", "url": "https://alphafold.ebi.ac.uk/entry/G3MYI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045998", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045998", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538665", "url": "https://www.ncbi.nlm.nih.gov/gene/538665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538665", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQVTWQA", "url": "https://omabrowser.org/oma/group/TQVTWQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYI7", "url": "https://www.orthodb.org/?gene=G3MYI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696517", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYI7", "url": "https://www.uniprot.org/uniprotkb/G3MYI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYI7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQLSKNLGDPSPPEEAPKPAVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQPPAPIAPMSQPPSLGGPMVQAPPLGGPMGKPPTPGVLMIHPPPPGAPLAQPPTPGVLMMHPSAPGAPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMTHPPPPGTPMAHPPPPPATPMAHPPPPGTPMAQPPAPGVLIPQPLTPGVLMVQPPAPGAPIAQPPPPAPLMAQPPPLGAPMAKPPGPGVLMIHPAGSRPPITQPPATGAPIVQPPAPAPPAQPMASWAPQAQPLILQIQSQVIRAPPPVPQGPQAPPAPLATPPGWQATSPGWQAPPQGWPATPLGWSTTQVTWPGPTIAWQAPLSVRPGPPPIRPGPPPIRPGPPPIRQAPPPIRQAPPLIRQAPPPIRPAPQVLATPPPLWQSLPPPPPLRQAPQTRLPTPQLRAAPPIRAAPQVPTAPPAPQMPTAPPAVPQAPPTVMPAPLPVPLSAPQAVHCPPIIWQAPKGQPPVPQEMPTSMEFQEVQQAQASLAWQAPKAQGQFWQSLPTQEAQRQGPPLVQLEQPFQGAPASQKALQIQLPTQQAQLSGSQAELPSMQLQPSWQGPSAALQGQPGAPLTGANFPMGSAKSLMTSSGESRASSMDRRTSSKDRRTSSKERKAPLKDRMIFGGTFCAPRAMPTAGAHLPTPWKNLPTTSETFNATPRVFPSTSQFQPASSNAFKGPSATSEAPKSLPFTLQDPFACIEALPAIPWVPQPNVNSSKASKAGPSILMATAAAPQVMAITQEASKTSAEPPRRSGKATRKKKHLNTEEEDSSGKMLNMCHWQAPRRWESLDLNDWEVQTPIQFLCDWEGPSTSRILSGWEGLSTSQILSGWEGPSTSWALSAWEGPSTSRALGLWESPVSPPSLIISELPTLAQGCGATQYDPKLETQPLSPLDERANALVQFLLVKDQAKVPIKRSEMVKFIIREYKDECLEIISRASHKLECVFGYQLKEIDPQNHSYILINKGRKGDTGVSYLDRPKLGLLMVVLSLIFMKGNCVREDLIFTFLCKLGLNIRETHGLFGNTKKLITEVFVREKYLEYRRIPFTEPEEHEFLWGPRAFLETSKMIVLKFLARLYKKDPRCWPYQYYEALAECESEDLDEDESGPDDKTDDPTSSPPPH", "length": 1183, "header": "tr|G3MYI7-1|G3MYI7_BOVIN Isoform 1 of MAGE family member L2 OS=Bos taurus OX=9913 GN=MAGEL2 PE=4 SV=1 CANONICAL=G3MYI7-1" }, "isoforms": [ { "isoform_ac": "G3MYI7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYI7/entry", "sequence": { "sequence": "MSQLSKNLGDPSPPEEAPKPAVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQPPAPIAPMSQPPSLGGPMVQAPPLGGPMGKPPTPGVLMIHPPPPGAPLAQPPTPGVLMMHPSAPGAPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMTHPPPPGTPMAHPPPPPATPMAHPPPPGTPMAQPPAPGVLIPQPLTPGVLMVQPPAPGAPIAQPPPPAPLMAQPPPLGAPMAKPPGPGVLMIHPAGSRPPITQPPATGAPIVQPPAPAPPAQPMASWAPQAQPLILQIQSQVIRAPPPVPQGPQAPPAPLATPPGWQATSPGWQAPPQGWPATPLGWSTTQVTWPGPTIAWQAPLSVRPGPPPIRPGPPPIRPGPPPIRQAPPPIRQAPPLIRQAPPPIRPAPQVLATPPPLWQSLPPPPPLRQAPQTRLPTPQLRAAPPIRAAPQVPTAPPAPQMPTAPPAVPQAPPTVMPAPLPVPLSAPQAVHCPPIIWQAPKGQPPVPQEMPTSMEFQEVQQAQASLAWQAPKAQGQFWQSLPTQEAQRQGPPLVQLEQPFQGAPASQKALQIQLPTQQAQLSGSQAELPSMQLQPSWQGPSAALQGQPGAPLTGANFPMGSAKSLMTSSGESRASSMDRRTSSKDRRTSSKERKAPLKDRMIFGGTFCAPRAMPTAGAHLPTPWKNLPTTSETFNATPRVFPSTSQFQPASSNAFKGPSATSEAPKSLPFTLQDPFACIEALPAIPWVPQPNVNSSKASKAGPSILMATAAAPQVMAITQEASKTSAEPPRRSGKATRKKKHLNTEEEDSSGKMLNMCHWQAPRRWESLDLNDWEVQTPIQFLCDWEGPSTSRILSGWEGLSTSQILSGWEGPSTSWALSAWEGPSTSRALGLWESPVSPPSLIISELPTLAQGCGATQYDPKLETQPLSPLDERANALVQFLLVKDQAKVPIKRSEMVKFIIREYKDECLEIISRASHKLECVFGYQLKEIDPQNHSYILINKGRKGDTGVSYLDRPKLGLLMVVLSLIFMKGNCVREDLIFTFLCKLGLNIRETHGLFGNTKKLITEVFVREKYLEYRRIPFTEPEEHEFLWGPRAFLETSKMIVLKFLARLYKKDPRCWPYQYYEALAECESEDLDEDESGPDDKTDDPTSSPPPH", "length": 1183, "header": "tr|G3MYI7-1|G3MYI7_BOVIN Isoform 1 of MAGE family member L2 OS=Bos taurus OX=9913 GN=MAGEL2 PE=4 SV=1 CANONICAL=G3MYI7-1" }, "locus": { "chromosome": "21", "start_pos": 1208637, "end_pos": 1205089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064156.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064156.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054620.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054620.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 104, "start_aa": "Thr", "end_pos": 104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 198, "start_aa": "Thr", "end_pos": 198, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr198", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 341, "start_aa": "Thr", "end_pos": 341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr341", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 377, "start_aa": "Thr", "end_pos": 377, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr377", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:538665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538665", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTL5-1", "protein_name": "MAGE family member L2", "gene_name": "Magel2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQLSTNLGDSSPPESPVPAVHSRPTVLMRAPPASSRAPPVPWDPPPVDLQAPMAAWQAPQPAWEASEGQLSAPVAQLAQPPTLGAPMVQAPSLGGAMAKPPTPGVLMVHQPPPGAQMAQSSTPGVLMLHPSVQGGSLGAHPPPPGTPMTHPPGTSMAHPPPPPPPPPPPGTPMTHPPPPGTPMAHPPPGNPMTHPPPPGNPMVQPLPPGTPMVHGGPHGTPMPHAPIAATPIAQQPTPGVLMAQQLTPGVLMVQPPAPGAQMVQPPPQTALMTQSPASITPMAKPSGPGVVMIHPPGARGPIIQTPVSGAPMAQTVLPPGQPLATWAPQGQPLILQIQSQVIRAPQQVPSVPQTPQVQLATPPGWQATTPNWQVTPQGWPTTPLTWQATQVTWQAPTIAWQAAPPVRQGPQPIRPGPPPIRPGPPPVLRQIPPVIRQIPTVMRQAPPLIRQAPPPIRPAPHGIAGQPQLWQVLPPPPPLRQAPQARLLLPRVPGAQVPTAPPVAQIHLVPQSGPRVPQTVLPAQLSIPIPVPQVAPQSAPRAVHCPSIIWQAPKGQAPVPQELPVPQELPVPQDLPVSEELPVPQELPVPQELQMPQELPVPQELQVQQELQVPEGLQVPLEFQEVQQAQAMGWRAPKVPTHFWQSVPAQDTQEQPTQITHVEQQQPFQGAAASPKALQTQLPTHQAQTTGLQAELPSVQVQPSWQGPPPILQAHPGTSATLTNFPRGSSRSRMTPSGEPGPSSLEPRGPPRERRAPAKDKKGPPKERMIIGATFCAPRGAPASKAYLPTAWKNLPASSETFPATSRVFPSTSHFQPASTDAFRGPSATSESPKSLPFALQDPYACVEALPAVPWVPYPDGNSSSACKAVPTILMVTAAAPQASATDAEASKSSEPPRRSGKATRKKKHLEPKEDNCGHSMPSRDRRGPRSWENPSQNDWEIQRAMQLLGDRESLYTPQGLNDWGYPNTSRMPSSLDGPSTSRDQGFCGGSGGSQTWMASEVPPSVSRGSSTAQEDPDRETQPLSPLDERANALVQFLLVKDQAKVPVQLSEMVNVVIREYKDDSLDIINRANTKLECTFGCQLKEVDAKTHTYIIVNKMAYPQCNLLASYLERPKFSLLMVVLSLIFMKGYCIRENLLFSFLFQLGLDVQETSSLFRITKKLITSVFVRHRYLEYRQIPFTEPAEYELLWGPRAFLETNRVHILRFLAALYENQPQIWSCQYLDSLAELEYKDANDEESHDSDDDSHDPTSSPHPH", "length": 1258 }, "evidence": [ { "id": "G3MYI7", "url": "https://omabrowser.org/oma/group/G3MYI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QZ04-1", "protein_name": "MAGE-like protein 2", "gene_name": "Magel2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQLSTNLGDSSPPESPVPAVHSRPTVLMRAPPASSRAPPVPWDPPPVDLQAPMAAWQAPQPAWEAPEGQLPAPVAQLAQPPGLGAPMVQAPPLGGGMAKPPTPGVLMVHQPPPGAPMAQSSTPGVLMLHPSVTGAPLAHPPPPGTPMTHPPGTSMAHPPPPPPPPPPPPPPGTPMTHPPPPGTPMGHHPPPGNPMTHPPPGNPMVHPLTHGAPMVHGGPHGTPMPHVPITGTPIAQQPTPGVLMAQQLTPGVLMVQPPAPGAPMVQPPPQAALMTQPAPSITPMAKPPGPGVVMIHPPGARGPIIQTPVSGAPMAQTVLPPGQPLATWAPQGQPLILQIQSQVIRAPPQVPSVPQAPQVQLATPPGWQATTPNWQVTPQGWPATPLTWQATQVTWQAPTIAWQATQPGRQGHSTIRTGHTPIRPGPAPLLRQIPPMIRQIQPVMRQAPPLIRQVPIRPAPHGIASQPQLWQVLPPPPPLRQAPQARLLLPRVPGTGQVSTVPPVAQIHLVPQSGPQVPQTVLPAQLSIPIPVPQAAAQSAPRTVHCPPIIWQAPKGQAPVPQELPVPQELPVPQELPVPQEVPVPQEIPVPQEIPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPLEFQEVQQAQAVGWRAPKVPPHFWQPVSAQEAQEQATQIAHVEQQQPFQGAPASSKALQTQLPTHQAQASGLQAELPSVQLQPSWQGPLPMLQAQPGASATLANFPRGSTRSRMAPSGEPGPSSLEPRGPPRERRAPARDKKGPPKERMFIGATFCAPRGASASRAYVPTAWKNLPATSETFPATSRVFPSTSHFQPASSNAFRGPSAASESPKSLPFALQDPYACVEALPAVPWVPYPDGNASSACKSVPAILMVAAAAPQASATAAEASKSSEPPRRPGKATRKKKHLEPKEDNCGHRLSSRDWRGPRTWGNPSHSDWEIQRAMQLLGDRESLYTPQGLNDWGCPNTSRMPRSLEGPSTSRDQEFCGDSGGSQTWMASEVPSVSRGSSAAQEDPDRESQPLSPLDERANALVQFLLVKDQAKVPVQLSEMVNVVIREYKDDSLDIINRANTKLECTFGCQLKEVDTKTHTYIIVNKMAYPQCNLLASYLERPKFSLLMVVLSLIFMKGYCIRENLLFSFLFQLGLDVQETSGLFRITKKLITSVFVRHRYLEYRQIPFTEPAEYELLWGPRAFLETNRVHILRFLAALYENQPQIWSCQYLDSLAELEYKDANAAAEESHDSDDDAHDPTSSPHPH", "length": 1284 }, "evidence": [ { "id": "G3MYI7", "url": "https://omabrowser.org/oma/group/G3MYI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJ55-1", "protein_name": "MAGE-like protein 2", "gene_name": "MAGEL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQLSKNLGDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPGWQATQQGWQATPLTWQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIRPGPPPVRQAPPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIPTSMEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTLAFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECEWEDTDEDEPDTGDSAHGPTSRPPPR", 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein 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"G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SEMA3G", "url": "https://www.uniprot.org/uniprotkb/G3MYK9", "locus": { "chromosome": "22", "start_pos": 48455608, "end_pos": 48445728, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046924", "url": "https://www.ensembl.org/id/ENSBTAG00000046924" } ] } } ], "crossref": [ { "id": "G3MYK9", "url": "https://alphafold.ebi.ac.uk/entry/G3MYK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046924", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046924", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100299041", "url": "https://www.ncbi.nlm.nih.gov/gene/100299041", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DLQAMYL", "url": "https://omabrowser.org/oma/group/DLQAMYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYK9", "url": "https://www.orthodb.org/?gene=G3MYK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010816133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010816133", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYK9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPSAWAVCCLLGGLLLRGGSPNPGPSVPRLRLSFRDLLSANRSAIFLGPRGSLDLQALYLDEYRDRLFLGGRDAIYSLRLDQTWPDPREVLWPPQPGQREECVHKGRDPLVECANFVRVLHPHNRTHLLACGTGAFQPTCALLAVGHRGEHVLHLEPRSMESGRGRCPHEPSRPFASTFVGGELYTGLNADFLGHEAMIFRSGGPRPALRSDSDQNLLHDPRFVLAARIPDNSDPDDDKVYFFFSETVPSPDGGPGRVTISRVGRVCVNDAGGQRVLVNKWSTFLKARLLCSVPGPGSAETHFDQLEDVFLLWPNSGKSLEVYALFSTVSAVFQGYAICVYHMADIWEVFKGPFAHQDGPQHQWGPYGGKVPFPRPGMCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFRPVRPRRGRPVLVKTHLAQQLRQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQGAGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVARLQLHQCETYGSACAECCLARDPYCAWDGASCTRYRPGSNKRRFRRQDIRHGNPALQCLGQSQEEETAGLVATTTVYGTEHNSTFLECLPKSPQAAAHWFLQRPGDERPEQQVKTDERVLQTEQGLLFRRLNRLDAGTYTCMTLEHGFSQVVVRLALEVIVPAQLDILFPRETRPEEPTARGGPTSPYSKAWYKDIMQLIGFANLPRVDEYCERVWCPSRSRTRGKQAKGKSWVGLELGKKVKSRVQAERNRTPREV", "length": 770, "header": "tr|G3MYK9-1|G3MYK9_BOVIN Isoform 1 of Semaphorin 3G OS=Bos taurus OX=9913 GN=SEMA3G PE=3 SV=2 CANONICAL=G3MYK9-1" }, "isoforms": [ { "isoform_ac": "G3MYK9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYK9/entry", "sequence": { "sequence": "MAPSAWAVCCLLGGLLLRGGSPNPGPSVPRLRLSFRDLLSANRSAIFLGPRGSLDLQALYLDEYRDRLFLGGRDAIYSLRLDQTWPDPREVLWPPQPGQREECVHKGRDPLVECANFVRVLHPHNRTHLLACGTGAFQPTCALLAVGHRGEHVLHLEPRSMESGRGRCPHEPSRPFASTFVGGELYTGLNADFLGHEAMIFRSGGPRPALRSDSDQNLLHDPRFVLAARIPDNSDPDDDKVYFFFSETVPSPDGGPGRVTISRVGRVCVNDAGGQRVLVNKWSTFLKARLLCSVPGPGSAETHFDQLEDVFLLWPNSGKSLEVYALFSTVSAVFQGYAICVYHMADIWEVFKGPFAHQDGPQHQWGPYGGKVPFPRPGMCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFRPVRPRRGRPVLVKTHLAQQLRQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQGAGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVARLQLHQCETYGSACAECCLARDPYCAWDGASCTRYRPGSNKRRFRRQDIRHGNPALQCLGQSQEEETAGLVATTTVYGTEHNSTFLECLPKSPQAAAHWFLQRPGDERPEQQVKTDERVLQTEQGLLFRRLNRLDAGTYTCMTLEHGFSQVVVRLALEVIVPAQLDILFPRETRPEEPTARGGPTSPYSKAWYKDIMQLIGFANLPRVDEYCERVWCPSRSRTRGKQAKGKSWVGLELGKKVKSRVQAERNRTPREV", "length": 770, "header": "tr|G3MYK9-1|G3MYK9_BOVIN Isoform 1 of Semaphorin 3G OS=Bos taurus OX=9913 GN=SEMA3G PE=3 SV=2 CANONICAL=G3MYK9-1" }, "locus": { "chromosome": "22", "start_pos": 48454604, "end_pos": 48445819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065486.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065486.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054644.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054644.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 698, "start_aa": "Thr", "end_pos": 698, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr698", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AC48-1", "protein_name": "Semaphorin 3G", "gene_name": "SEMA3G", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRAAAALGWLWGALLAAGSSPPRLRLPYRELLGMNRSVLFFGHRGFLGFRSLYLDEYRDRLFIGGKDVLYSLRLDRASADTKEIYWPPLPGQTEECFRKGKDPATDCANYVRLLQPYNRTHLLACGTGACHPVCTFIYVGHRGETQHAFILDPGSTESGRGRCPHEPDRAFASTIIGGELYAGLTADFLGRDPGIFRSTGTRAALRTEVDQRLLNDPKFVAAYMIPDNDDRDDDKAYFFFTEKVVEADSKEHTIVSRVARVCVNDAGGQRVLVNKWSTFNKARLVCSVPGPGGIDTYFDELEDVFLLRTKDGKNPEIYALFSTVSHVFQGSAVCVYRMADIREVFNGPFAHRDSPLHQWGAYEGRVPYPRPGVCPSKTTNQPRRPYSSTKELPDEVLHFARAHPLMYRAVRPRHHRPLLVKTDLQQRLLQLVVDRVDTEDGQHDVLFLGTDAGSVLKVVVLQMQSSAVTEEVVLEELQVFKVPVPITQMEISVKRQKLYVGASLGVAQVRLHQCKSYGTACAECCLARDPYCAWDGTACTRYQPSGKRRHVRHTSSVHQCLDQNLTVDDLEHVEEKVLYGMEHNSTFLECVPRSPQASVQWFVQRPPDEQRDEVKTDERVLQTEQGLLFRQLHRRDAGVYYCKTLEHGFTQTVAKTALEVLGGEQLARATPRQREDRHPPCPEPWLAAPAPKTWYKDILHLASSADRQRVEEQCLRLWCGHRKGKMAKGKHALAGMDVVKKGRVAKPHGERIRVPRQAAAT", "length": 761 }, "evidence": [ { "id": "G3MYK9", "url": "https://omabrowser.org/oma/group/G3MYK9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LNH0-1", "protein_name": "Semaphorin 3G", "gene_name": "Sema3g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARCSAWAICCLLGSLLFHMGSPNPGPSTSVPRLRLSYRDLLTTNRSAIFLGPRGSLDLQVMYLDEYRDRLFLGGRDALYSLRLDQAWPDPREVLWPPQPGQKVECVRKGKDPLTECANFVRVLQPHNRTHLLACGTGAFQPICTFITVGHRGEHVLHLDPSSIENGRGRCPHEPSRPFASTFVGGELYTGLTADFLGREAMIFRSGGPRPALRSDSDQSLLHDPRFVMAARIPDNSDRDDDKVYFFFSETVPSPDGGPGHVTVSRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKNLEVYALFSTVSAVFRGFAVCVYHMVDIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRGHPLMFQPVRPRRGRPVLVKTHLAQQLCQIVVDRVEAEDGTYDVIFLGTDSGSVLKIIALQGSGLPEPEEVVLEELQVFKVPTPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPYCAWDGTSCARYRPSSGKRRFRRQDIRHGNPAVQCLGQGQSQDKASGLVTRVFGTEHNSTFLECRPKSPQAAVRWFLQRPGDKGADQVKTDERVVQTDQGLLFRRLSRLDAGNYTCTTLEHGFSQTVVRFALEVIAAVQLDSLFLREPRLEEPSAWRSVASASPKTWYKDILQLTGFANLPRVDEYCERVWCRGVGERSGSFRGKGKQAKGKSWAGLELGRKMKSRVQAEHNRTPREVEAT", "length": 780 }, "evidence": [ { "id": "G3MYK9", "url": "https://omabrowser.org/oma/group/G3MYK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SIW2-1", "protein_name": "Semaphorin 3G", "gene_name": "SEMA3G", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPSAWAICCLLGGLLLHGGSPSPGPSVPRLRLSYRDLLSVNRSAIFLGPRGSLDLRALYLDEYRDRLFLGGRDAIYSLRLDQAWPDAREVLWPPQPGQREECVHKGRDPLVECANFVRVLQPHNRTHLLACGTGAFQPTCALIAVGHRGEHVLHLEPYSVESGRGRCPHEPSRPFASTFVGGELYTGLNADFLGREAMIFRSGGPRPALRSDSDQNLLHDPRFVMAARIPDNSDQDDDKVYFFFSETVPSPDGGLSRVTVSRVGRVCMNDMGGQRVLVNKWSTFLKARLLCSVPGPGGAETHFNQLEDVFLLWPSAGKSLEVYALFSMVSTVFQGYAVCVYHMADIWEVFKGPFAHQDGPQHQWRPYGGKVPFPRPGMCPSKMTSQPGRPFGSTKDYPDEVLQFARAHPLMFRPVRPWRDRPVLVKTHLAQQLRQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQEGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVAQLQLHQCETYGSACAECCLARDPYCAWDGASCTRYRPGTSKRRIRRQDIRHGNPALQCLGQSQDEEAAGLVAATTVYGTEHNSTFLECLPKSPQATVHWFLQSRGDEGPNQVKTDERVLQTEQGLLFRRLNRLDAGTYTCMTLEHGFSQVVVRLALEVIVATQLNTLFPRGLRPEEPATREGLASTPSKAWYKDILQLIGFANLPRVDEYCERVWCPSRSRSRSKQAKGKNWVGLELGKKVKSRVQAERNRTPREVEAT", "length": 771 }, "evidence": [ { "id": "G3MYK9", "url": "https://omabrowser.org/oma/group/G3MYK9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4LFA9-1", "protein_name": "Semaphorin-3G", "gene_name": "Sema3g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPSAWAICCLLGSLLFHVGIPSPGPSPSVPRLRLSYRDLLSTNRSAIFLGPRGSLDLQVMYLDEYRDRLFLGSRDALYSLRLDQAWPDPREVLWLPQPGQKVECVRKGKDPLTECANFVRVLQPHNRTHLLACGTGAFQPICTFITVGHRGEHVLRLDASSVENGRGRCPHEPSRPFASTFVGGELYTGLTADFLGREAMIFRSGGPRPALRSDSDQSLLHEPRFVMAARIPDNSDRDDDKVYFFFSETVPSPDGGPGHVTISRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMVDIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRDHPLMFQPVRPRRGRPVLVKTHLAQRLRQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQGGGLTEPEEVVLEELQVFKVPTPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPYCAWDGTACARYRPSSGKRRFRRQDIRHGNPAVQCLGQGQSQNKAASGLMTRVFGTEHNSTFLECLPKSPQAAVRWFLQRPGDKGTDQVKTDERVVQTAQGLLFRRLSRHDAGNYTCTTLEHGFSQTVVRFALEVIAAVQLDSLFLRESRLEEPSAWGSLASASPKTWYKDILQLTGFANLPRVDEYCERVWCRGVGERSGSFRGKGKQAKGKSWAGLELGKKMKSRVLAEHNRTPREVEAT", "length": 780 }, "evidence": [ { "id": "G3MYK9", "url": "https://omabrowser.org/oma/group/G3MYK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NS98-1", "protein_name": "Semaphorin-3G", "gene_name": "SEMA3G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPSAWAICWLLGGLLLHGGSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGPQGSLNLQAMYLDEYRDRLFLGGLDALYSLRLDQAWPDPREVLWPPQPGQREECVRKGRDPLTECANFVRVLQPHNRTHLLACGTGAFQPTCALITVGHRGEHVLHLEPGSVESGRGRCPHEPSRPFASTFIDGELYTGLTADFLGREAMIFRSGGPRPALRSDSDQSLLHDPRFVMAARIPENSDQDNDKVYFFFSETVPSPDGGSNHVTVSRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMADIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQAGGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVAQLRLHQCETYGTACAECCLARDPYCAWDGASCTHYRPSLGKRRFRRQDIRHGNPALQCLGQSQEEEAVGLVAATMVYGTEHNSTFLECLPKSPQAAVRWLLQRPGDEGPDQVKTDERVLHTERGLLFRRLSRFDAGTYTCTTLEHGFSQTVVRLALVVIVASQLDNLFPPEPKPEEPPARGGLASTPPKAWYKDILQLIGFANLPRVDEYCERVWCRGTTECSGCFRSRSRGKQARGKSWAGLELGKKMKSRVHAEHNRTPREVEAT", "length": 782 }, "evidence": [ { "id": "G3MYK9", "url": "https://omabrowser.org/oma/group/G3MYK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "neuropilin binding", "id": "GO:0038191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038191", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" }, { "name": "negative regulation of axon extension", "id": "GO:0030517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030517", "evidence": [ { "database": "UniProtKB", "id": "G3MYK9", "url": "https://www.uniprot.org/uniprotkb/G3MYK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, 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"MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAGGGR", "length": 114, "header": "tr|G3MYP6-1|G3MYP6_BOVIN Isoform 1 of NOTCH regulated ankyrin repeat protein OS=Bos taurus OX=9913 GN=NRARP PE=3 SV=1 CANONICAL=G3MYP6-1" }, "isoforms": [ { "isoform_ac": "G3MYP6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYP6/entry", "sequence": { "sequence": "MSQAELSTCSAPQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAFGGHQDIVLYLITKAKYAGGGR", "length": 114, "header": "tr|G3MYP6-1|G3MYP6_BOVIN Isoform 1 of NOTCH regulated ankyrin repeat protein OS=Bos taurus OX=9913 GN=NRARP PE=3 SV=1 CANONICAL=G3MYP6-1" }, "locus": { "chromosome": "11", "start_pos": 106326588, "end_pos": 106326247, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064804.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064804.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054683.1", "url": 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"evidence": [ { "database": "UniProtKB", "id": "G3MYP6", "url": "https://www.uniprot.org/uniprotkb/G3MYP6" } ], "pmid": "" }, { "name": "blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "id": "GO:0002043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002043", "evidence": [ { "database": "UniProtKB", "id": "G3MYP6", "url": "https://www.uniprot.org/uniprotkb/G3MYP6" } ], "pmid": "" }, { "name": "branching involved in blood vessel morphogenesis", "id": "GO:0001569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001569", "evidence": [ { "database": "UniProtKB", "id": "G3MYP6", "url": "https://www.uniprot.org/uniprotkb/G3MYP6" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "G3MYP6", "url": "https://www.uniprot.org/uniprotkb/G3MYP6" } ], "pmid": "" }, { "name": "negative regulation of Notch 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"length": 1173, "header": "tr|G3MYQ1-1|G3MYQ1_BOVIN Isoform 1 of Formin homology 2 domain containing 1 OS=Bos taurus OX=9913 GN=FHOD1 PE=3 SV=2 CANONICAL=G3MYQ1-1" }, "locus": { "chromosome": "18", "start_pos": 34874135, "end_pos": 34858058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063472.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063472.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054688.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054688.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 609, "start_aa": "Thr", "end_pos": 609, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr609", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:787862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787862", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ1" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ1" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ1" } ], "pmid": "" }, { 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"MDGRGRSTGGSRQLSLRRERGYLQSQLAVKLMLLSANQRRVARGLSGCGPEPTWSPQWGHGEAALAGWSGSPHIMLVHLFRVGIRGGPVPGKPLLPLRFQTFSAVRSSDGRPSACLLGVMAQLRSQLRARLPRAAPAPIRSPSAWRWVGGVLLGPLVLSKCPRLSLVALCEAEEAPLARSRPRVLEPRFNWTLFWQFLRPHLLVLGAAIVLALGAALVNVQIPLLLGQLVEIVAKYTRDHAGSFLTESRSLSTHLLLLYGLQGLLTFGYLVLLSRIGERMAVDLRRALFCNLLRQDIEFFDAKKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSALRKLSRQCQEQVSEFPPSPPVLPSFSAPCAPRSPSPSASWLSNFWVPCRSPGQQGVADEALGNVRTVRAFAMEQREEERYGAELEGSRCKAEELGRGIALFQGLSNIAFNCMVLGTLFVGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSILFGQVVRGLSAGARVFEYMTLSPGIPLSGGCSLPREHLRGSITFHNVSFSYPCRPGFPVLRDFSLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVTLDGQDLRTLDPSWLRSQVIGFISQEPVLFGTTIMENIRFGKVDASDEEVYAAAREANAHEFITSFPEGYNTIVGERGATLSGGQKQRLAIARALIKQPAVLILDEATSALDSESERVVQEALDRASAGRTVLVIAHRLSTVRAAHRIVVMAHGRVCEVGTHEELLKKGGLYSELIRRQALDTPPPEAAQVLGHRHSKS", "length": 825, "header": "tr|G3MYQ9-1|G3MYQ9_BOVIN Isoform 1 of Mitochondrial potassium channel ATP-binding subunit OS=Bos taurus OX=9913 GN=ABCB8 PE=3 SV=4 CANONICAL=G3MYQ9-1" }, "isoforms": [ { "isoform_ac": "G3MYQ9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9/entry", "sequence": { "sequence": "MDGRGRSTGGSRQLSLRRERGYLQSQLAVKLMLLSANQRRVARGLSGCGPEPTWSPQWGHGEAALAGWSGSPHIMLVHLFRVGIRGGPVPGKPLLPLRFQTFSAVRSSDGRPSACLLGVMAQLRSQLRARLPRAAPAPIRSPSAWRWVGGVLLGPLVLSKCPRLSLVALCEAEEAPLARSRPRVLEPRFNWTLFWQFLRPHLLVLGAAIVLALGAALVNVQIPLLLGQLVEIVAKYTRDHAGSFLTESRSLSTHLLLLYGLQGLLTFGYLVLLSRIGERMAVDLRRALFCNLLRQDIEFFDAKKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMVATPALMGVGTLMGSALRKLSRQCQEQVSEFPPSPPVLPSFSAPCAPRSPSPSASWLSNFWVPCRSPGQQGVADEALGNVRTVRAFAMEQREEERYGAELEGSRCKAEELGRGIALFQGLSNIAFNCMVLGTLFVGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSILFGQVVRGLSAGARVFEYMTLSPGIPLSGGCSLPREHLRGSITFHNVSFSYPCRPGFPVLRDFSLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVTLDGQDLRTLDPSWLRSQVIGFISQEPVLFGTTIMENIRFGKVDASDEEVYAAAREANAHEFITSFPEGYNTIVGERGATLSGGQKQRLAIARALIKQPAVLILDEATSALDSESERVVQEALDRASAGRTVLVIAHRLSTVRAAHRIVVMAHGRVCEVGTHEELLKKGGLYSELIRRQALDTPPPEAAQVLGHRHSKS", "length": 825, "header": "tr|G3MYQ9-1|G3MYQ9_BOVIN Isoform 1 of Mitochondrial potassium channel ATP-binding subunit OS=Bos taurus OX=9913 GN=ABCB8 PE=3 SV=4 CANONICAL=G3MYQ9-1" }, "locus": { "chromosome": "4", "start_pos": 113621224, "end_pos": 113605676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064324.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064324.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054696.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054696.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1369007", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1369007", "resource": "Reactome", "description": "Mitochondrial ABC transporters" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "mitochondrial ATP-gated potassium channel complex", "id": "GO:0062157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062157", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" }, { "name": "mitochondrial potassium ion transmembrane transport", "id": "GO:0140141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140141", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ9", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYQ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 825, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYQ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYQ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ9" }, { "id": "PS50929", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50929" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transmembrane type-1", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 532, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MYQ9", "database": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYS9-1", "uniprot_ac": "G3MYS9", "uniprot_id": "G3MYS9_BOVIN", "mass": { "chemical_mass": 19829.0, "monoisotopic_mass": 19829.0 }, "refseq": { "ac": "NP_001193113", "name": "membrane protein FAM174A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193113" }, "gene_names": [ { "name": "FAM174A", "type": "recommended", "evidence": [ { "id": "G3MYS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYS9" } ] }, { "name": "FAM174A", "type": "synonym", "evidence": [ { "id": "NP_001193113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193113" } ] }, { "name": "TMEM157", "type": "synonym", "evidence": [ { "id": "NP_001193113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193113" } ] } ], "protein_names": [ { "name": "Transmembrane protein 157", "type": "recommended", "evidence": [ { "id": "G3MYS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYS9/entry#names_and_taxonomy" } ] }, { "name": "membrane protein FAM174A precursor", "type": "synonym", "evidence": [ { "id": "NP_001193113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193113" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYS9", "url": "https://www.uniprot.org/uniprotkb/G3MYS9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM174A", "url": "https://www.uniprot.org/uniprotkb/G3MYS9", "locus": { "chromosome": "7", "start_pos": 99830680, "end_pos": 99808217, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045909", "url": "https://www.ensembl.org/id/ENSBTAG00000045909" } ] } } ], "crossref": [ { "id": "G3MYS9", "url": "https://alphafold.ebi.ac.uk/entry/G3MYS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045909", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045909", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614659", "url": "https://www.ncbi.nlm.nih.gov/gene/614659", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614659", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614659", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAPHCCC", "url": "https://omabrowser.org/oma/group/KAPHCCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYS9", "url": "https://www.orthodb.org/?gene=G3MYS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28607:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28607:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193113", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193113", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYS9", "url": "https://www.uniprot.org/uniprotkb/G3MYS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYS9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPTLCSCCLSRALASALLLSLLLPELSGPSAGRPPAARAAPDLQPAARGPRTRPPPPPGSSAARPAGRAPALEAAGARGAEGGNGSTPGAGPAADDPGGKAGAGGPAGGVLAVSPDPGDKPMTQRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPLEQDDEEDDNTLFDANHPRR", "length": 193, "header": "tr|G3MYS9-1|G3MYS9_BOVIN Isoform 1 of Transmembrane protein 157 OS=Bos taurus OX=9913 GN=FAM174A PE=3 SV=1 CANONICAL=G3MYS9-1" }, "isoforms": [ { "isoform_ac": "G3MYS9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYS9/entry", "sequence": { "sequence": "MQPTLCSCCLSRALASALLLSLLLPELSGPSAGRPPAARAAPDLQPAARGPRTRPPPPPGSSAARPAGRAPALEAAGARGAEGGNGSTPGAGPAADDPGGKAGAGGPAGGVLAVSPDPGDKPMTQRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPLEQDDEEDDNTLFDANHPRR", "length": 193, "header": "tr|G3MYS9-1|G3MYS9_BOVIN Isoform 1 of Transmembrane protein 157 OS=Bos taurus OX=9913 GN=FAM174A PE=3 SV=1 CANONICAL=G3MYS9-1" }, "locus": { "chromosome": "7", "start_pos": 99830123, "end_pos": 99808416, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063075.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063075.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054718.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", 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"reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYU8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 202, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYU8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYU8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"monoisotopic_mass": 128565.0 }, "refseq": {}, "gene_names": [ { "name": "HELB", "type": "recommended", "evidence": [ { "id": "G3MYV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ] } ], "protein_names": [ { "name": "DNA helicase B", "type": "recommended", "evidence": [ { "id": "G3MYV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYV2/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.12", "type": "synonym", "evidence": [ { "id": "G3MYV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYV2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection. Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit the nucleases catalyzing resection, such as EXO1, BLM and DNA2, possibly via the 5'-3' ssDNA translocase activity of HELB. As cells approach S phase, DNA end resection is promoted by the nuclear export of HELB following phosphorylation. Acts independently of TP53BP1. Unwinds duplex DNA with 5'-3' polarity. Has single-strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dATP as substrates. 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"id": "G3MYV2", "url": "https://alphafold.ebi.ac.uk/entry/G3MYV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020806", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020806", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17933", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17933", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18809", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18809", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MYV2", "url": "https://www.orthodb.org/?gene=G3MYV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYV2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "DNA replication, synthesis of primer", "id": "GO:0006269", "url": 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activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "5'-3' DNA helicase activity", "id": "GO:0043139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043139", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" }, { "name": "DNA replication factor A complex", "id": "GO:0005662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005662", "evidence": [ { "database": "UniProtKB", "id": "G3MYV2", "url": "https://www.uniprot.org/uniprotkb/G3MYV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. 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"url": "https://alphafold.ebi.ac.uk/entry/G3MYX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048065", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048065", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100847716", "url": "https://www.ncbi.nlm.nih.gov/gene/100847716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100847716", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100847716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR10484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010808604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYX0", "url": "https://www.uniprot.org/uniprotkb/G3MYX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYX0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIWDAVTYTEHAKRKAVTAMDVVYALKRQGRTLYGFGG", "length": 103, "header": "tr|G3MYX0-1|G3MYX0_BOVIN Isoform 1 of Histone H4 OS=Bos taurus OX=9913 GN=LOC100847716 PE=3 SV=1 CANONICAL=G3MYX0-1" }, "isoforms": [ { "isoform_ac": "G3MYX0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYX0/entry", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIWDAVTYTEHAKRKAVTAMDVVYALKRQGRTLYGFGG", "length": 103, "header": "tr|G3MYX0-1|G3MYX0_BOVIN Isoform 1 of Histone H4 OS=Bos taurus OX=9913 GN=LOC100847716 PE=3 SV=1 CANONICAL=G3MYX0-1" }, "locus": { "chromosome": "11", "start_pos": 86542226, "end_pos": 86541918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064851.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064851.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054759.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054759.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100847716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100847716", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3MYX0", "url": "https://www.uniprot.org/uniprotkb/G3MYX0" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "G3MYX0", "url": "https://www.uniprot.org/uniprotkb/G3MYX0" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": 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"categories": [] }, { "id": "ENSBTAG00000030474", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030474", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518612", "url": "https://www.ncbi.nlm.nih.gov/gene/518612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": 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] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005209561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYX2", "url": "https://www.uniprot.org/uniprotkb/G3MYX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYX2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEASRKLVCRQRQVLFFFLFLHLALAGFESRRYSVVEEAEGSSFVTNLAKDLGLGQGELSSRGARVISKGNKLYLQLDQESGDLLLNKKLDREELCGQTEPCVLRFQVLLENPLEFFQAELQVTDINDHTPVFRDGDMLLKISENSLPGTTFPLKNAQDMDVGQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKVLDREEEAEFRLTLTAQDGGSPPRSGTAHIYIEVVDINDNAPEFEQPFYRVKIPEDSPKGFLVVKVSATDVDTGVNGEISYSLSQASEDISKTFEINAMTGEIRLKKQLDFETTQSYEVNIEAIDTGSLSGKCTVLIQVVDVNDNAPEVTMSALTGQIPENSPETVVAVFSVSDLDSEENGKVSCSVQYDLPFLLKSSMENFYTLVTERPLDRETRAEYNIIIAVTDLGTPKLKTEHNITVLVSDVNDNAPTFTQTSYTLWVRENNSPALHIGSVSATDTDAGANAQVTYSLLPPPDPLVPLASLVSINPDNGHLFALTSLDYEALRAFEFRVGATDRGSPALSSQALVRVLVADANDNAPFVLYPLQNASAPCTELVPRAAEPGYLVTKVVAVDGDAGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDTPKQRLVVLVKDNGEPPLSASVTLHVLLVDGFSQPYLPAPEAEAAASAPADPLTVYLVVALASVSSLFLFSVLVFVAVRLCRRGGAASAGRCPVAEGHFPGHLVDVSGTGTLSQSYQYEVCLMGGTGTGEFKFLKPVVPKFQSHFPGPEINPQF", "length": 788, "header": "tr|G3MYX2-1|G3MYX2_BOVIN Isoform 1 of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC518612 PE=4 SV=3 CANONICAL=G3MYX2-1" }, "isoforms": [ { "isoform_ac": "G3MYX2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYX2/entry", "sequence": { "sequence": "MEASRKLVCRQRQVLFFFLFLHLALAGFESRRYSVVEEAEGSSFVTNLAKDLGLGQGELSSRGARVISKGNKLYLQLDQESGDLLLNKKLDREELCGQTEPCVLRFQVLLENPLEFFQAELQVTDINDHTPVFRDGDMLLKISENSLPGTTFPLKNAQDMDVGQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKVLDREEEAEFRLTLTAQDGGSPPRSGTAHIYIEVVDINDNAPEFEQPFYRVKIPEDSPKGFLVVKVSATDVDTGVNGEISYSLSQASEDISKTFEINAMTGEIRLKKQLDFETTQSYEVNIEAIDTGSLSGKCTVLIQVVDVNDNAPEVTMSALTGQIPENSPETVVAVFSVSDLDSEENGKVSCSVQYDLPFLLKSSMENFYTLVTERPLDRETRAEYNIIIAVTDLGTPKLKTEHNITVLVSDVNDNAPTFTQTSYTLWVRENNSPALHIGSVSATDTDAGANAQVTYSLLPPPDPLVPLASLVSINPDNGHLFALTSLDYEALRAFEFRVGATDRGSPALSSQALVRVLVADANDNAPFVLYPLQNASAPCTELVPRAAEPGYLVTKVVAVDGDAGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDTPKQRLVVLVKDNGEPPLSASVTLHVLLVDGFSQPYLPAPEAEAAASAPADPLTVYLVVALASVSSLFLFSVLVFVAVRLCRRGGAASAGRCPVAEGHFPGHLVDVSGTGTLSQSYQYEVCLMGGTGTGEFKFLKPVVPKFQSHFPGPEINPQF", "length": 788, "header": "tr|G3MYX2-1|G3MYX2_BOVIN Isoform 1 of Cadherin domain-containing protein OS=Bos taurus OX=9913 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377271" }, "gene_names": [ { "name": "OR8B9", "type": "recommended", "evidence": [ { "id": "G3MZ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ39" } ] }, { "name": "OR8B9", "type": "synonym", "evidence": [ { "id": "NP_001377271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377271" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MZ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ39/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8B12", "type": "synonym", "evidence": [ { "id": "NP_001377271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377271" } ] }, { "name": "olfactory receptor family 8 subfamily B member 9", "type": "synonym", "evidence": [ { "id": "NP_001377271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377271" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377271", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377271" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MZ39", "url": "https://www.uniprot.org/uniprotkb/G3MZ39#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ39", "url": "https://www.uniprot.org/uniprotkb/G3MZ39" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8B9", "url": "https://www.uniprot.org/uniprotkb/G3MZ39", "locus": { "chromosome": "29", "start_pos": 27839808, "end_pos": 27840743, "strand": "+", "evidence": 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"id": "G3MZ39-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADNTSSVIEFILTGLTDQAQLKIPLFFLFLSFYVVTVVGNLGLITLIGLNSHLHIPMYFFLFNLSFIDFSYSTTLTPKMLMGFVSEKNIISYTGCITQFFFFCFFVFSESYILSAMAYDRYVAICKPLVYTVTMSPQVCLLLLLGVYGMGVFGAVAHMGNIMFMTFCGDNLVNHYMCDIIPLLELSCNSSYVNLLVVFIVVTIGIGVPIVTIFISYGFILSSILHISSTEGRSKAFSTCSSHIIVVSLFFGSGAFMYLKPPSILPLDQGKVSSVFYTAVVPMLNPLIYSLRNKDVKVALKKTLSIKIFS", "length": 311, "header": "tr|G3MZ39-1|G3MZ39_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8B9 PE=3 SV=1 CANONICAL=G3MZ39-1" }, "isoforms": [ { "isoform_ac": "G3MZ39-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ39/entry", "sequence": { "sequence": 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"evidence": [ { "id": "G3MZ39", "url": "https://omabrowser.org/oma/group/G3MZ39/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8VF62-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAANTSSVAEFILVGLTDQPQLQIPLFFLFLGFYIVTMVGNLGLITLIGLNSHLHIPMYFFLFNLSFIDFSYSTTLTPKMLVGFVLRKNIISYAGCMTQFFFFCFFVFSESYILSAMAYDRYVAICKPLLYSVTMSPQVCSYLLSGVYGMGVFGAVAHMGNLQFISFCADNIINHYMCDIIPLLELSCNSSYINLLVVFIVVTIGIGVPIVTIFISYGFILSSILHISSKEGRSKAFSTCTSHIIVVSLFFGSGAFMYLKPPSSLPLDQGKVSSVFYTAVVPMFNPLIYSLRNKDVKIALKKTLSRKNFS", "length": 311 }, "evidence": [ { "id": "G3MZ39", "url": "https://omabrowser.org/oma/group/G3MZ39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377455" }, "gene_names": [ { "name": "OR2T60", "type": "recommended", "evidence": [ { "id": "G3MZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ81" } ] }, { "name": "OR2T60", "type": "synonym", "evidence": [ { "id": "NP_001377455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377455" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3MZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ81/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2T8", "type": "synonym", "evidence": [ { "id": "NP_001377455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377455" } ] }, { "name": "olfactory receptor family 2 subfamily T member 60", "type": "synonym", "evidence": [ { "id": "NP_001377455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377455" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377455" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MZ81", "url": "https://www.uniprot.org/uniprotkb/G3MZ81#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ81", "url": "https://www.uniprot.org/uniprotkb/G3MZ81" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2T60", "url": "https://www.uniprot.org/uniprotkb/G3MZ81", "locus": { "chromosome": "7", "start_pos": 41530052, "end_pos": 41529114, "strand": "-", "evidence": 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J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. 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"uniprot_canonical_ac": "Q9QYI6-1", "protein_name": "DnaJ homolog subfamily B member 9", "gene_name": "Dnajb9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPQSVFVFAICILMITELILASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANSRKEYDTIGHSAFTNGKGQRGNGSPFEQSFNFNFDDLFKDFNFFGQNQNTRSKKHFENHFHTRQDGSSRQRHHFQEFSFGGGLFDDMFEDMEKMFSFSGFDTTNRHTVQTENRFHGSSKHCRTVTQRRGNMVTTYTDCSGQ", "length": 222 }, "evidence": [ { "id": "G3MZ88", "url": "https://omabrowser.org/oma/group/G3MZ88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBS3-1", "protein_name": "DnaJ homolog subfamily B member 9", "gene_name": "DNAJB9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPQSIFIFAICILMITELILASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDTLGHSAFTSGKGQRGSGSSFEQSFNFNFDDLFKDFGFFGQNQNTGSKKRFENHFQTRQDGGSSRQRHHFQEFSFGGGLFDDMFEDMEKMFSFSGFDSTNQHTVQTENRFHGSSKHCRTVTQRRGNMVTTYTDCSGQ", 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"MKMKIIVYFCIWAVAWAIPVPQIKPLERHAVDKSVNVNLLAKSKVPIQDALNDNNTTKESGGLMHENERGRQQDIQDGYKGDRNGSEWAELGGKSSSTGSMLANEKGNTEDLKGGTGKPETYDHDGMQGQEESITANGLRGQVSIVHDAGVANGSHIDGIAENNSQNAGVGNTSQSEDATVVQEDGHQVAGSSNSTGQEAEINGDSCRNGADTSETTPQREDERNGNEEVGVLPVGSGAGNGEDVGLDNFEGSPSGNGADEDEDKGSGDGEGEEIGNGEKGSDTSKGQEGQSHGEEDDEDNSLGQNSVSSEDDGPGDKEDSHVIDGDNISKSEEDSAGIPEDNGSQKTEDTQKPSHRENKAVENRLTEKSQPTAIGKNQDKGMEMESPSSGHRNNVTKEAGKVNEDKESKGQHGMIVGKGNVKTQGEIDIIQGAGQKLESGNKLGPSQVHSDSNSDGHDSYEFDDESMQGDDPNSSDESNGSDDANSEGDNNHSSRGDASYNSDESNDNGNDSGSKGDDDGSDNTSDANDNGSDGNDDNGGDDSGKSGNSKDKSDSSDSSDSSDSDSSDSSESDSKSDSDSSDSSDSDSKSDNDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSDSSDSSDSKSDSSDSSDSSDSDSSDSSDSSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSDSSDSSDSKSDSSDSSDSSDSDSSDSSDSSDSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSDSSDSKSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSSDSDSSDSSDSSDSSDSKSDSSDSSDSSDSDSSDSDSSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSDSSDSSDSSNSSDSDSKSDSDSSDSSDSSDSSDSSDSKSDSSDSSDSDSSDSSDSSDSSDSSNSSDSDSKSDSDSSNSSDSSDSSDSKSDSSDSSDSSDSKSDSSDSSDSDSKSDSDSSDSSDSSDSDSSDSSDSSDSDSSDSSDSDSKSDSDSSDSSNSSDSSDSSDSDTKSDSDSSDSSDSDSSDSSDSSDSSDSSDSSDSDSSNSSDSDSKSDSDSSDSSDSDSSDSSDSDSSDSSDSDSSDSSDSNDSNTKSDSDSSDSSDSSDSKSKSGNGNHNGGSSDSDSDSEGSDSNHSTSDD", "length": 1190, "header": "tr|G3MZB1-1|G3MZB1_BOVIN Isoform 1 of Dentin sialophosphoprotein OS=Bos taurus OX=9913 GN=DSPP PE=4 SV=2 CANONICAL=G3MZB1-1" }, "isoforms": [ { "isoform_ac": "G3MZB1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZB1/entry", "sequence": { "sequence": "MKMKIIVYFCIWAVAWAIPVPQIKPLERHAVDKSVNVNLLAKSKVPIQDALNDNNTTKESGGLMHENERGRQQDIQDGYKGDRNGSEWAELGGKSSSTGSMLANEKGNTEDLKGGTGKPETYDHDGMQGQEESITANGLRGQVSIVHDAGVANGSHIDGIAENNSQNAGVGNTSQSEDATVVQEDGHQVAGSSNSTGQEAEINGDSCRNGADTSETTPQREDERNGNEEVGVLPVGSGAGNGEDVGLDNFEGSPSGNGADEDEDKGSGDGEGEEIGNGEKGSDTSKGQEGQSHGEEDDEDNSLGQNSVSSEDDGPGDKEDSHVIDGDNISKSEEDSAGIPEDNGSQKTEDTQKPSHRENKAVENRLTEKSQPTAIGKNQDKGMEMESPSSGHRNNVTKEAGKVNEDKESKGQHGMIVGKGNVKTQGEIDIIQGAGQKLESGNKLGPSQVHSDSNSDGHDSYEFDDESMQGDDPNSSDESNGSDDANSEGDNNHSSRGDASYNSDESNDNGNDSGSKGDDDGSDNTSDANDNGSDGNDDNGGDDSGKSGNSKDKSDSSDSSDSSDSDSSDSSESDSKSDSDSSDSSDSDSKSDNDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSDSSDSSDSKSDSSDSSDSSDSDSSDSSDSSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSDSSDSSDSKSDSSDSSDSSDSDSSDSSDSSDSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSDSSDSKSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSSDSDSSDSSDSSDSSDSKSDSSDSSDSSDSDSSDSDSSDSSDSSDSDSKSDSDSSDSSDSKSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSDSSDSSDSSNSSDSDSKSDSDSSDSSDSSDSSDSSDSKSDSSDSSDSDSSDSSDSSDSSDSSNSSDSDSKSDSDSSNSSDSSDSSDSKSDSSDSSDSSDSKSDSSDSSDSDSKSDSDSSDSSDSSDSDSSDSSDSSDSDSSDSSDSDSKSDSDSSDSSNSSDSSDSSDSDTKSDSDSSDSSDSDSSDSSDSSDSSDSSDSSDSDSSNSSDSDSKSDSDSSDSSDSDSSDSSDSDSSDSSDSDSSDSSDSNDSNTKSDSDSSDSSDSSDSKSKSGNGNHNGGSSDSDSDSEGSDSNHSTSDD", "length": 1190, "header": "tr|G3MZB1-1|G3MZB1_BOVIN Isoform 1 of Dentin sialophosphoprotein OS=Bos taurus OX=9913 GN=DSPP PE=4 SV=2 CANONICAL=G3MZB1-1" }, "locus": { "chromosome": "6", "start_pos": 102500864, "end_pos": 102494936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063098.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063098.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054907.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054907.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-3000178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3000178", "resource": "Reactome", "description": "ECM proteoglycans" } ], "orthologs": [ { "uniprot_canonical_ac": "P97399-1", "protein_name": "Dentin sialophosphoprotein", "gene_name": "Dspp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMKIIIYICIWATAWAIPVPQLVPLERDIVENSVAVPLLTHPGTAAQNELSINSTTSNSNDSPDGSEIGEQVLSEDGYKRDGNGSESIHVGGKDFPTQPILVNEQGNTAEEHNDIETYGHDGVHARGENSTANGIRSQVGIVENAEEAESSVHGQAGQNTKSGGASDVSQNGDATLVQENEPPEASIKNSTNHEAGIHGSGVATHETTPQREGLGSENQGTEVTPSIGEDAGLDDTDGSPSGNGVEEDEDTGSGDGEGAEAGDGRESHDGTKGQGGQSHGGNTDHRGQSSVSTEDDDSKEQEGFPNGHNGDNSSEENGVEEGDSTQATQDKEKLSPKDTRDAEGGIISQSEACPSGKSQDQGIETEGPNKGNKSIITKESGKLSGSKDSNGHQGVELDKRNSPKQGESDKPQGTAEKSAAHSNLGHSRIGSSSNSDGHDSYEFDDESMQGDDPKSSDESNGSDESDTNSESANESGSRGDASYTSDESSDDDNDSDSHAGEDDSSDDSSGDGDSDSNGDGDSESEDKDESDSSDHDNSSDSESKSDSSDSSDDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNSSSDSSDSSGSSDSSDSSDTCDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSSSSDSSDSSSCSDSSDSSDSSDSSDSSDSSDSSSSDSSSSSNSSDSSDSSDSSSSSDSSDSSDSSDSSDSSGSSDSSDSSASSDSSSSSDSSDSSSSSDSSDSSDSSDSSDSSESSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSDSKDSSSDSSDGDSKSGNGNSDSNSDSNSDSDSDSEGSDSNHSTSDD", "length": 934 }, "evidence": [ { "id": "G3MZB1", "url": "https://omabrowser.org/oma/group/G3MZB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62598-1", "protein_name": "Dentin sialophosphoprotein", "gene_name": "Dspp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTKIIIYICIWATAWAIPVPQLVPLERDIVEKSADVPFLAHPGTAAQNELHINNATNDDSPKGSELGRQVHSNGGYERDRNGSESIAVGGKSSPTQPILANAQGNSAKEREDVETYGHDGIHAGGENSTANGIRGQVGIAENAEEAKESKVHGQPHQDTKTGLASDTSQNGDATLVQENEPQVAGSKNSTNHEVGTHGSGVAAQETTPQREGEGSENQGAEVTPSIGEGAGLDNTEGSPSGNGIEEDEDTGSGDGVGADAGDGRESHDGTEGHEGQSSGGNNDNRGQGSVSTEDDDSKEQEGSPNGRGGDNTSSSEETGIEEGDGTQTTQDNQNLSPTEGGIISQAEACPSGQSQNQGLETEGSSTGNKSSITKESGKLSGSKDSNGHHGMELDKRNSPKQGESDKPQGAAEKSDTHNNMGHSRIGSSSNSDGHDSYDFDDESMQGDDPNSSDESNGSDGSDDANSESAIENGNHGDASYTSDESSDNGSDSDSHAGEDDSSDDTSDTDDSDSNGDDDSESKDKDESDNSNHDNDSDSESKSDSSDSDSDSSDSSDSSDSSDSSETSDSSDSSDTSDSSDSSDSSDSSNSSDTSDSSDSSDGDSSDGDSSDSDSSDSDSSNSSDSDSSDSSDSSSSDSSDSDSDSKDSTSDSSDDNSKSGNGNSDSDSDSDSDSEGSDSNHSTSDD", "length": 687 }, "evidence": [ { "id": "G3MZB1", "url": "https://omabrowser.org/oma/group/G3MZB1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NZW4-1", "protein_name": "Dentin sialophosphoprotein", "gene_name": "DSPP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIITYFCIWAVAWAIPVPQSKPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD", "length": 1301 }, "evidence": [ { "id": "G3MZB1", "url": "https://omabrowser.org/oma/group/G3MZB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "dentinogenesis", "id": "GO:0097187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097187", "evidence": [ { "database": "UniProtKB", "id": "G3MZB1", "url": "https://www.uniprot.org/uniprotkb/G3MZB1" } ], "pmid": "" }, { "name": "odontoblast differentiation", "id": "GO:0071895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071895", "evidence": [ { "database": "UniProtKB", "id": "G3MZB1", "url": "https://www.uniprot.org/uniprotkb/G3MZB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZB1", "url": "https://www.uniprot.org/uniprotkb/G3MZB1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MZB1", "url": "https://www.uniprot.org/uniprotkb/G3MZB1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "G3MZB1", "url": "https://www.uniprot.org/uniprotkb/G3MZB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1048, "end_pos": 1050, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1184, "end_pos": 1186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 862, "end_pos": 864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 899, "end_pos": 901, "annotation": "n_glycosylation_sequon" }, { "start_pos": 952, "end_pos": 954, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZB1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1190, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZB1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZB1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1048, "end_pos": 1050 }, { "start_pos": 1096, "end_pos": 1098 }, { "start_pos": 1139, "end_pos": 1141 }, { "start_pos": 1184, "end_pos": 1186 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 511, "end_pos": 513 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 55, "end_pos": 57 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 862, "end_pos": 864 }, { "start_pos": 899, "end_pos": 901 }, { "start_pos": 952, "end_pos": 954 }, { "start_pos": 966, "end_pos": 968 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"https://omabrowser.org/oma/group/SHHLEPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZC5", "url": "https://www.orthodb.org/?gene=G3MZC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34033:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34033:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21590", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21590", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005227091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZC5", "url": "https://www.uniprot.org/uniprotkb/G3MZC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZC5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPLGRETWAQRLGTFRASPSAFMAGPEGEDLGRDLLSDLRSEKLSEPMKVALLALSLEYPDQLWPDAPAAEAAATSLLDTLVLLPPRPSALRRPLLLAATTALAAGGALNPASGASGRLLPLLLGLASGRDLGRSFCPASEQRPLQATAWECLRELESCRPGLLGGCLGLLRALLGREGPAQPLSLLLALALRNALVIQARAGAGLQGLLTAGESSMEGGPWNWMLAEEGEVHLQPQAPSWPAAEEDECGLAALELSPEEARELRATVAQLLDASYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHAMLALKAAFGEALFTAQDEALLLRRLTLAAQHPALPLPTHLFYLHCLLNFPENWPLGPTGEEAAPLLLGSQLCRGLLPSLLHEPMALLARLHLLCLLCVEDEEKEGKGQDRSPRHYLEELLAGLRQRAALDGGPRALATLCFQASYLVAHCLAGQPVVLIPLTQGLAQLYRARPALAPHFVDLLDHVGPELQEPLRVALRQEVASRPGREEALRWHLQMLASVADGDAQSATLSFLRAAAAHCTDWGLQQALLRVCRALLRAGVGGGLADLLQELARQLEDPDGQDHARLYYILLAHLAGPKLGVALGPSLAAPALASSLVAENQGFAAALMVQEAPAPIRLSVGPRRAEGAVPVLRLQVEVLEPVYSLELRFRVEGQLYAPLGAVHVPCLCPGRPTRPLLLPLQPRRPAPARLAVRALYSTPSGLTCHAHLPPLLVAFADLFLPFPQPPEGAQLDFFEELWDSCLPKGTESRLWCPLGPEGLEALVSRHLEPFVVVAQPPVSYLVAIRLPPDSRLLLRLEAAQADGVPVALRTDDWAVLPLAGDYLRGLSAAG", "length": 877, "header": "sp|G3MZC5-1|AP5B1_BOVIN Isoform 1 of AP-5 complex subunit beta-1 OS=Bos taurus OX=9913 GN=AP5B1 PE=2 SV=1 CANONICAL=G3MZC5-1" }, "isoforms": [ { "isoform_ac": "G3MZC5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZC5/entry#G3MZC5-1", "sequence": { "sequence": "MGPLGRETWAQRLGTFRASPSAFMAGPEGEDLGRDLLSDLRSEKLSEPMKVALLALSLEYPDQLWPDAPAAEAAATSLLDTLVLLPPRPSALRRPLLLAATTALAAGGALNPASGASGRLLPLLLGLASGRDLGRSFCPASEQRPLQATAWECLRELESCRPGLLGGCLGLLRALLGREGPAQPLSLLLALALRNALVIQARAGAGLQGLLTAGESSMEGGPWNWMLAEEGEVHLQPQAPSWPAAEEDECGLAALELSPEEARELRATVAQLLDASYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHAMLALKAAFGEALFTAQDEALLLRRLTLAAQHPALPLPTHLFYLHCLLNFPENWPLGPTGEEAAPLLLGSQLCRGLLPSLLHEPMALLARLHLLCLLCVEDEEKEGKGQDRSPRHYLEELLAGLRQRAALDGGPRALATLCFQASYLVAHCLAGQPVVLIPLTQGLAQLYRARPALAPHFVDLLDHVGPELQEPLRVALRQEVASRPGREEALRWHLQMLASVADGDAQSATLSFLRAAAAHCTDWGLQQALLRVCRALLRAGVGGGLADLLQELARQLEDPDGQDHARLYYILLAHLAGPKLGVALGPSLAAPALASSLVAENQGFAAALMVQEAPAPIRLSVGPRRAEGAVPVLRLQVEVLEPVYSLELRFRVEGQLYAPLGAVHVPCLCPGRPTRPLLLPLQPRRPAPARLAVRALYSTPSGLTCHAHLPPLLVAFADLFLPFPQPPEGAQLDFFEELWDSCLPKGTESRLWCPLGPEGLEALVSRHLEPFVVVAQPPVSYLVAIRLPPDSRLLLRLEAAQADGVPVALRTDDWAVLPLAGDYLRGLSAAG", "length": 877, "header": "sp|G3MZC5-1|AP5B1_BOVIN Isoform 1 of AP-5 complex subunit beta-1 OS=Bos taurus OX=9913 GN=AP5B1 PE=2 SV=1 CANONICAL=G3MZC5-1" }, "locus": { "chromosome": "29", "start_pos": 43900261, "end_pos": 43897527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064301.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064301.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054921.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054921.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 745, "start_aa": "Thr", "end_pos": 745, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr745", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "G3MZC5", "url": "https://www.uniprot.org/uniprotkb/G3MZC5" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] }, { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "G3MZC5", "url": "https://www.uniprot.org/uniprotkb/G3MZC5" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] } ], "pathway": [ { "id": "bta:509087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509087", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LS78-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "Ap5b1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGPLSREAWAQRLGAFRASPSAFLAGAEGEDLGRDLLSDLRSEKLSEQTKVSLLTLSLEYSDKLWSDAPAAEAAATSLLDTLVLLPSKPSALRRLLLLAATTALVSGGALGPTSGASCRLLPLLLGLASGRDMGRSFGTLSEQRHLQATACECLGELERCKPGLLAGSLGILRSLLGQTGPIQPVSLLLALVLHNTLVVPSRPGAEIGAGLQGLLVAGVSSSGSCPWDWTLAEEWDAHLQPQAPSWPTTGEEHGFPLLKPSPEEARELKAAVAQLLDTSYLLTSVAQAQLLWLLGWALRGLRGQPPVVFKPQLVRLLGTAQLTLLHSVLALKAAFGEALFTAQDEALLLRRLTLVAQHPALPSPTHLFYLNCILSFPENCPLGLEGEEAAPLLLGPQLSRGLMPSLLHDPMVLLARLHLLCLLCADAEEEEKGHVHSPRWYLQELLAGLQQRAALDGGPQALATLCFQASYLVASCLAGQPTVRTSLVHGLAQLYRARPSLAPHFVDLLDQVSPELREPLRVVLQQEVVARPGKNESLCWHLRMLAKVAEGDAQRATLSFLQAAAIHCTDWGLQQALLRVCRALLRTGGGDGLADLLQVLARQLEDADGRDHARLYYILFSHLSSSKLGMALGPSLAVPALASSLVAENQGFASTLMVQETPAPIQLSVGPQKAKGTLPVLHLQVEALEAPVYSLELRFRVAGQLYGPLEAVHIPCLCPGQPAHPLCLTLQPRRPAPARLHVEALYTTPAGLTCHAHLHPLSVKFADLFLPFPQLPKGSELCFFDDLWNSCLPKGVESRMWCPLGPQGLEALVSQHLEPFVVVAQPPTTYLIAVQLPPDSMLLLRLEKAQVDGVPVALRTDNWAVLPLVGDYLRSLAAH", "length": 879 }, "evidence": [ { "id": "G3MZC5", "url": "https://omabrowser.org/oma/group/G3MZC5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZVB0-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "Ap5b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPLSREAWAQRLGSFRASPSAFLAGAEGEDLGHDLLSDLRSEKLSELIKVSLLTLSLEYSDKLWPDALAAEAAATSLLDTLVLLPSKPSALRRLLLLAATTALVSGGALGPTSEASSRLLPLLLGLASGQDMGRSFGTTSEQRHLQATACECLGELERCKPGLLAGALGVLRSLLGQKGPIQPVSLLLALVLHNTLVVQSRFGAGLQGLLVAKDSSPGSCPWDWTLAEEWDDHLKPQAHGWPTAGEEERDFPILDPNPEDTRELKAAVAQLLDTSYLLTPVAQAQLVWLLGWALQGLRGQPPVLFKPQLVRLLGTAQLTLLHSVLSLKAAFGEALFTAQDEALLLRRLTLVAQHPALPSPTHLFYLHCILSFPENCPLGPEGEEAAPLLLGPQLRRGLMPSLLHDPMVLLARLHLLCLLCADDEEEEKGQLQGPQWFLQELLAGLQQRAAVDGGPRALATLCFQASYLVTSCLTRQPTVQTSLVHGLAQLYRARPSLAPHFVDLLDEVSPELREPLRKVLLREVVARPGKNEALRWHLQMLAKVAEGATQSAILGFLQAAAIHCTDWGLHQALLRVCRALLRTGGGEGLADLLQELARQLENADGRDHARLYYVLLSHLSSSKLGMALGPSLAAPALASSLMAENQGFASALMVQETSAPIQLSVGPQKAKGPLPVLHLQVQALDTPVYSLELRFRVEGQLYEPVEAVHIPSVRPGQPAHPLHLPLQPRSPAPARLHVRALYTTPAGLTCHAHLPPLSVNFADLFLPFPQLPKGSELCFFDELWNSCLPKGVESRVWCPLGPQGLEALVSQHLEPFVVVAQPPTTYLIAVRLPPHSMLLLRLEKAQVHGVPVALRTDDWAVLPLVGDYLRGLAAH", "length": 876 }, "evidence": [ { "id": "G3MZC5", "url": "https://omabrowser.org/oma/group/G3MZC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QPU4-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "ap5b1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIADLWDQRISAFLLSPSQFLATSTSEIFLAELLHELRNDKINDQLKILLVSALLEHPTILCPSASVGEETALELLSIFSQTPQKSISLKCNVMLAITNVIICTSCLATHTKMAEDWLDLLFQTIQDTNDYRCGQSQQPLRATACDCLREMETCSPGLLSQKLEALYLLKQQETSVLHQSYCILYTLGLKNAIRILTNQKEVTDFEFKSILGGNEGFAWRTNQNFLPINMIVQVPQLPQGLDCKELKSIMSLLLEESYLLTPISQSSLMRDLVEVVAMVPGLSPTLFKSQLLRLFGTAEVVLMHATLFMKDTFTDSLFTAEDENFLLKRLVGSAQHPLLRIPEKLFYMDCILHFPENRPISSSGEECLPVLVTPRLAASLLPTVFNDSATMLCRLNLLCLVHLEADEGEADKGIAYLFDHIMALLKIVDSDGSREVVVTSFRALFIFLKHFNGMEELSEKLIDKLRDIYSRHCRLAPNLIGLADRIQECLDDPIWSVKLLRGLQKCIMEMPPLQLTIHNLSWHLKVLKRVAKEGQITQRNTIYLLLNVLINSNLCERGKWQIGNAVLAVCRNLLEHPSIDQVFIELADLLQYISVNYNDTDIKDHARFYYTLLTNLSWEKLTGVLAKGPDGGRAKERSHSAIMAESEGIASNLTVCKTERHVLQLIKIQDKVSQSTSESSESLEDTGEARNWLEVYQEQFQTPGFGSEVTLRYNLTHAEETDPLFDRVFSICLHFEFKDSNYAKVSDIHVPCVFRDRKPPEVNVQLKPFQPYPTTLCFSAMFTTQDGRSWHSQLPDVSISFPEIFLPLPIATNASSACREQVFDHIWESAASGNPDKSAISLFCFKPGDESLADLIKTHFQGYLITDQQSERFWKVLFFLPPMCHVLLRITQAEDAVQVSIATDNWELLPFVNSYLRNITDDCSTTVTDG", "length": 931 }, "evidence": [ { "id": "G3MZC5", "url": "https://omabrowser.org/oma/group/G3MZC5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RRK6-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "AP5B1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPQSRETWAQRLGTFRASPSAFMEGPEGEDLARDLLSDLRSEKLSEPTKVSLLALSLEYPTQLWPDASAAEAAANSLLDTLVLLPPRPSALRRPLLLAATTALAAGGALGPTSGASRRLLPLLLGLASGRDLGRGFSPASEQRPLQATAWECLRELESCKPGLLGGCLGLLRGLLGQEGPVQPLSLLLALALRNALMIQARARASLQGLLTAGDCPTEGAPWNWTLAEAGDAHLQPQAPSWPAAEEGECGLTALELSPEEARELRAAVAQLLDASYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHAVLALKAAFGEALFTAQDEALLLRRLILAAQHPALPLPAHLFCLHCLLSFPENWPLGPAGEEAAPLLLGSQLCRGLLPSLLHDPMALLARLHLLCLLCVEDEDKEEQGQDPSPRRYLEELLAGLRQRAALDGGPRALATLCFQASYLVARCLAGHPVVLTPLTHGLAQLYRARPALTPHFADLLDQVGPELGEPLKVVLRQEVVSRPGRDEALRWHLQMLAKVADGDAQGATLSFLQAAATHCTDWGLQQALLKVCRALLRAGVVRGLADLLQALARQLEDPDGRDHARLYYILLAHLARPKLGVALGPSLAAPALASSLVAENQGFAKALMVQEAPAPIRLSLGPRRAEGPVPVLQLQVEVLEPVYSLELRFSVERQLYAPLGAVHVPCLCPSRPARPLLLPLQPRRPAPARLAVRALYTTPAGLTCHAHLPPLLVNFADLFLPFPQPPEGAKVDFFEELWDSCLPKGAESHLWCPLGPHGLEALVSRHLEPFVVVAQPPTSYCVAIRLPPNSKLLLRLEAAQADGVPVALRTDDWAVLPLVGDYLRGLAAAG", "length": 877 }, "evidence": [ { "id": "G3MZC5", "url": "https://omabrowser.org/oma/group/G3MZC5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2VPB7-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "AP5B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPLSRDAWAQRLGAFRASPSAFMAGPEGEDLGRDLLSDLRSEKLSEQTKVSLLALSMEYPAQLWPDASAAEVAATSLLDTLVLLPPRPSALRRPLLLAATTALAAGGALGPTSGASCRLLPLLLGLAAGSDLGRGFVPASEQRPLQATACECLRELESCKPGLLGGSLGLLRGLLGQEGPVQPLSLLLALALRNTLVLQSRVGAGLGGLLTDKVSPTGGGPWDWTLVEEGDGRLQPQAPSWPAAEEGEGERSLTAREHSPEEARELRAAVIQLLDTSYLLTPVAQAQLLWLLGWALRGLQGQPPALFKPQLVRLLGTAQLTLLHAMLALKAAFGEALFTAQDEALLLRRLTLAAQHPALPPPTHLFYLHCVLSFPENWPLGPEGEEAAPLLLGPQLCRGLLPSLLHDPMALLARLHLLCLLCAEEEEEEKGQLPSPRHYLEELLAGLRQRAALDGGPRALATLCFQASYLVACCLAGQPTVLTPLIHGLAQLYQARPMLAPHFVDLLDQVDSELREPLKVVLRQVVVSRPGRDEALCWHLQMLAKVADGDAQSATLNFLQAAAAHCTNWDLQQGLLRVCRALLRAGVRGGLVDLLQVLARQLEDPDGRDHARLYYILLAHLAAPKLGVALGPSLAAPALASSLVAENQGFVAALMVQEAPALVRLSLGSHRVKGPLPVLKLQPEALEPIYSLELRFRVEGQLYAPLEAVHVPCLCPGRPARPLLLPLQPRCPAPARLDVHALYTTSTGLTCHAHLPPLFVNFADLFLPFPQPPEGAGLGFFEELWDSCLPEGAESRVWCPLGPQGLEGLVSRHLEPFVVVAQPPTSYCVAIHLPPDSKLLLRLEAALADGVPVALRTDDWAVLPLAGDYLRGLAAAV", "length": 878 }, "evidence": [ { "id": "G3MZC5", "url": "https://omabrowser.org/oma/group/G3MZC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TAP4-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "Ap5b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPLGREAWAQRLGAFRASPSAFLAGAEGEDLGRDLLSDLRSEKLSEQTKVSLLTLSLEYSDKLWPDAPAAEAAATSLLDTLVLLPTRPSALRRLLLLAATTALVSGDALGPTSGASCRLLPLLLGLASGRDLGRSFGTPSEQRHLQATACECLGELERCKPGLLAGALGMLRSLPGQTGPIQPVSLLLALVLHDTLVVQSRSGAGLQGLLVAEDFSTGSCPWDWTLAEEWDAHLKPQGPSWPTAGEEERGFPVLEPSPEDARELKAAVAQLLDTSYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHSVLSLKAAFGEALFTAQDEALLLRRLTLGAQHPALPSPTHLFYLHCILSFPENCPLGPEGEEAAPLLLGPQLCRGLMPSLLHDPTVLLARLHLLCLLCADDEEEEKDQTQGPQWFLQEVLAGLQQRAALDGGPRALATLCFQASYLVTNCLTRHSTVQTFLIRGLAQLYRARPSLAPHFVDLLDQVSPELREPLREVLLQEAVARPGESEALCWHLQMLAKVAEGATQSTTLSFLQAAAVHCTDWGLHQALLRVCRALLRTGGGDGLANLLQELARQLENADGRDHARLYYVLLSHLSSSKLGMALGPSLAAPALASSLMAENQGFSSALMVQETSAPIQLSVGPQQAKGPLPVLCLQVQALDAPVYSLELRFRVEGQLYEPLEAVHIPCLRPGQPAHPLYLLLQPRCPAPARLHVRALYSTSAGLTCHARLPPLSVNFADLFLPFPRLPKGSELRFFDELWNSCLPKGVESRVWCPLGQQGLEALVSQYLEPFVVLAQPPTTYLIAIRLPPASMLLLRLEKAQVDGVPVALRTDDWAVLPLVGDYLRGLAAH", "length": 876 }, "evidence": [ { "id": "G3MZC5", "url": "https://omabrowser.org/oma/group/G3MZC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "G3MZC5", "url": "https://www.uniprot.org/uniprotkb/G3MZC5" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "G3MZC5", "url": "https://www.uniprot.org/uniprotkb/G3MZC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "AP-type membrane coat adaptor complex", "id": "GO:0030119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030119", "evidence": [ { "database": "UniProtKB", "id": "G3MZC5", "url": "https://www.uniprot.org/uniprotkb/G3MZC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 877, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZC5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZC5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 745 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", 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"MAGKALSLLPPLLLAAAGLAGLLLLCVPTRDIREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDAQGGGISSYADNPSGAGQSLVECLNQALRDVPKERHAGTPLYLGATAGMRLLNLTSPEASANVLAAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPTEDPANEVQLRLYGQRYRVYTHSFLCYGRDQVLRRLLARALQTHGSHPCWPRGYSTHVMLWDVYESPCTAAQRPQAFNRSTRVSLAGSSDPALCRSLVSQLFNSSSCHFSRCSFNGVFQPPVAGKFIAFSAFFYTMDFLRTVMGLPVATLQQLEGAVVTLCNQTWSELQARAPDDRARLPDYCAGAMFVQQLLSRGYGFDERSFGGVTFQKKAGDTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFAAMLLAAFALLLHQARSTKSASTI", "length": 495, "header": "tr|G3MZH7-1|G3MZH7_BOVIN Isoform 1 of apyrase OS=Bos taurus OX=9913 GN=ENTPD2 PE=3 SV=1 CANONICAL=G3MZH7-1" }, "isoforms": [ { "isoform_ac": "G3MZH7-1", "url": "https://www.uniprot.org/uniprotkb/G3MZH7/entry", "sequence": { "sequence": "MAGKALSLLPPLLLAAAGLAGLLLLCVPTRDIREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDAQGGGISSYADNPSGAGQSLVECLNQALRDVPKERHAGTPLYLGATAGMRLLNLTSPEASANVLAAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPTEDPANEVQLRLYGQRYRVYTHSFLCYGRDQVLRRLLARALQTHGSHPCWPRGYSTHVMLWDVYESPCTAAQRPQAFNRSTRVSLAGSSDPALCRSLVSQLFNSSSCHFSRCSFNGVFQPPVAGKFIAFSAFFYTMDFLRTVMGLPVATLQQLEGAVVTLCNQTWSELQARAPDDRARLPDYCAGAMFVQQLLSRGYGFDERSFGGVTFQKKAGDTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFAAMLLAAFALLLHQARSTKSASTI", "length": 495, "header": "tr|G3MZH7-1|G3MZH7_BOVIN Isoform 1 of apyrase OS=Bos taurus OX=9913 GN=ENTPD2 PE=3 SV=1 CANONICAL=G3MZH7-1" }, "locus": { "chromosome": "11", "start_pos": 106086426, "end_pos": 106081333, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063714.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063714.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054974.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054974.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-8850843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8850843", "resource": "Reactome", "description": "Phosphate bond hydrolysis by NTPDase proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PS27-1", "protein_name": "apyrase", "gene_name": "ENTPD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARRAAAVLLLLALGCLLGILLLCLGSGDARGPPSFKYGIVLDAGSSHTAVFIYKWPADKENDTGVVSEHSMCDVEGPGISSYSSKPPAAGKSLEHCLSQAMRDVPKEKHADTPLYLGATAGMRLLRIADPPSSDAVLSAVMATLKSYPFDFRGAKILSGEEEGVFGWITANYLLENFIKRGWLGEWIQSKKKTLGAMDFGGASTQITFETSDAIEDPKNEVMLKLYGQPYKVYTHSFLCYGRDQVLKRLLSKVLQAENYQETVANPCWPTGYRKSLSLSSIYDSPCTEKERPGLPLNTTVVVSGTGNGNLCAVHVNKLFDFTSCSFSHCSFDGVFQPEVSGNFIAFSAFFYTVDFIRTVMERPVHSPSDLKDAAETICATSWNELYQKAPRLEKRLPDYCATSTFVYLLITKGYNFNNRSFPSIAFQKKAGETSIGWALGYMLNLTNMIPAQEPASHRSMLYNYWVILILLFVITTLTALLTAVYLLRRSKSSTI", "length": 496 }, "evidence": [ { "id": "G3MZH7", "url": "https://omabrowser.org/oma/group/G3MZH7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287AER5-1", "protein_name": "apyrase", "gene_name": "ENTPD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARKVLPLLLPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVSQHSSCDVHGGGISSYADNPSSAGQSLVACLDQALRDVPKERHVGTPLYLGATAGMRLLNLTSPEASANVLAAVTRTLAQYPFDCRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRSGTLGAMDLGGASTQITFETASPAEDPANEVQLRLYGHHYRVYTQSFLCYGRDQVLRRLLASALQSHGFHPCWPRGYSTHVLLQDVYESPCTAAQRPQTFNSSARVRVSGRSDPALCRGLVSELFNVSSCRFSRCSFNGVFQPPVTGSFIAFSAFFYTVEFLRTGMGLPVATLQQLEAAAVTVCNQSWSELQARAPGRQAHLPHYCAGAMFVQQLLSRGYGFDERAFGGVTFQKKAGDTAVGWALGYMLNLTNLIPADPPGLRKGADFGSWVVLLLLFAAMLLAAVVLLGLQARSSKAPSAI", "length": 495 }, "evidence": [ { "id": "G3MZH7", "url": "https://omabrowser.org/oma/group/G3MZH7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35795-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 2", "gene_name": "Entpd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL", "length": 495 }, "evidence": [ { "id": "G3MZH7", "url": "https://omabrowser.org/oma/group/G3MZH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55026-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 2", "gene_name": "Entpd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGKLVSLVPPLLLAAVGLAGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVRGGGISSYANDPSRAGQSLVECLEQALRDVPKDRYASTPLYLGATAGMRLLNLTSPEATAKVLEAVTQTLTRYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPDNEVHLRLYGQHYRVYTHSFLCYGRDQVLQRLLASALQIHRFHPCWPKGYSTQVLLREVYQSPCTMGQRPQTFNSSATVSLSGTSNAALCRDLVSGLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLKTVMGLPVGTLKQLEDATETTCNQTWAELQARVPGQQTRLPDYCAVAMFIHQLLSRGYRFDERSFRGVVFEKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL", "length": 495 }, "evidence": [ { "id": "G3MZH7", "url": "https://omabrowser.org/oma/group/G3MZH7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8H1D8-1", "protein_name": "Probable apyrase 4", "gene_name": "APY4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQRSNARSRSNINSDMVDPPEVQTSPGNHRSSPSTAAKPKSKRTKSIIFVIVACVTIALGLLFIGYSILRSGRNRRVSLHYSVIIDGGSSGTRVHVFGYRIESGKPVFDFGEENYASLKLSPGLSAYADNPEGVSESVTELVEFAKKRVHKGKLKKSDIRLMATAGMRLLELPVQEQILDVTRRVLRSSGFDFRDEWASVISGSDEGVYAWVVANHALGSLGGEPLKTTGIVELGGASAQVTFVSTELVPSEFSRTLAYGNVSYNLYSHSFLDFGQDAAQEKLSESLYNSAANSTGEGIVPDPCIPKGYILETNLQKDLPGFLADKGKFTATLQAAGNFSECRSAAFAMLQEEKGKCTYKRCSIGSIFTPNLQGSFLATENFFHTSKFFGLGEKEWLSEMILAGKRFCGEEWSKLKVKYPTFKDENLLRYCFSSAYIISMLHDSLGVALDDERIKYASKAGEEDIPLDWALGAFILNTATATFDYSGKSRKILDLSNVAKYKI", "length": 503 }, "evidence": [ { "id": "G3MZH7", "url": "https://omabrowser.org/oma/group/G3MZH7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y5L3-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 2", "gene_name": "ENTPD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLPSTI", "length": 495 }, "evidence": [ { "id": "G3MZH7", "url": "https://omabrowser.org/oma/group/G3MZH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" }, { "name": "GDP phosphatase activity", "id": "GO:0004382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004382", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" }, { "name": "UDP phosphatase activity", "id": "GO:0045134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045134", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" }, { "name": "apyrase activity", "id": "GO:0004050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004050", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribonucleoside triphosphate catabolic process", "id": "GO:0009203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009203", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" }, { "name": "nucleoside diphosphate catabolic process", "id": "GO:0009134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009134", "evidence": [ { "database": "UniProtKB", "id": "G3MZH7", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "20988", "name": "", "equation": "ATP + 2 H2O = AMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB25-1", "O18956-1", "A0JND9-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "G3MZH7-1" ], "evidence": [ { "id": "20988", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20988" } ] }, { "id": "23680", "name": "", "equation": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB25-1", "O18956-1", "Q3ZC91-1", "Q1LZ78-1", "F1MRW7-1", "A0JND9-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "G3MZH7-1" ], "evidence": [ { "id": "23680", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23680" } ] }, { "id": "36795", "name": "", "equation": "a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB25-1", "O18956-1", "A0JND9-1", "G3X6Y8-1", "A0A3Q1MDD8-1", "G3MZH7-1" ], "evidence": [ { "id": "36795", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36795" } ] }, { "id": "36799", "name": "", "equation": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB25-1", "E1BPW0-1", "O18956-1", "G5E5P3-1", "A0AAA9S9V5-1", "A0JND9-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "G3MZH7-1" ], "evidence": [ { "id": "36799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36799" } ] }, { "id": "64876", "name": "", "equation": "UDP + H2O = UMP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB25-1", "E1BPW0-1", "O18956-1", "G5E5P3-1", "A0JND9-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "G3MZH7-1" ], "evidence": [ { "id": "64876", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64876" } ] }, { "id": "64896", "name": "", "equation": "UTP + 2 H2O = UMP + 2 phosphate + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB25-1", "O18956-1", "A0JND9-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "G3MZH7-1" ], "evidence": [ { "id": "64896", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64896" } ] }, { "id": "64900", "name": "", "equation": "UTP + H2O = UDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MB25-1", "O18956-1", "Q2HJF8-1", "Q5E9M9-1", "A0JND9-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "G3MZH7-1", "A0AAF6YME1-1" ], "evidence": [ { "id": "64900", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64900" } ] }, { "id": "R-BTA-8851089", "name": "NTPDase2 hydrolyzes nucleoside triphosphates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MZH7-1" ], "evidence": [ { "id": "R-BTA-8851089", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8851089" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] } ] }, { "uniprot_ac": "A0A3Q1M7R9", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDD8", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] } ] }, { "uniprot_ac": "A0A3Q1MR43", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] } ] }, { "uniprot_ac": "A0A3Q1MS44", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MS44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS44" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MS44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS44" } ] } ] }, { "uniprot_ac": "A0A3Q1MU57", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] } ] }, { "uniprot_ac": "A0A3Q1NMG4", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] } ] }, { "uniprot_ac": "A0AAA9RUK3", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] } ] }, { "uniprot_ac": "A0AAA9RXI8", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] } ] }, { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9S9V5", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] } ] }, { "uniprot_ac": "A0AAA9SPF3", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] } ] }, { "uniprot_ac": "A0AAA9SX42", "gene_name": "TDRD12", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] } ] }, { "uniprot_ac": "A0AAA9T2L7", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0AAA9T2L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2L7" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0AAA9T2L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2L7" } ] } ] }, { "uniprot_ac": "A0AAA9T674", "gene_name": "DDX56", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T674" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T674" } ] } ] }, { "uniprot_ac": "A0AAA9T8W7", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0AAA9T8W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8W7" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0AAA9T8W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8W7" } ] } ] }, { "uniprot_ac": "A0AAA9TGZ3", 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"uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPW0", "gene_name": "ENTPD5", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "E1BPW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPW0" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "E1BPW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPW0" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { 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"id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": 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H(+).", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] } ] }, { "uniprot_ac": "Q2NKY8", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] } ] }, { "uniprot_ac": "Q2NKZ1", "gene_name": "CCT7", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] }, { "ec_number": "5.6.1.7", "activity": "ATP + H2O + an unfolded polypeptide = ADP + phosphate + a folded polypeptide.", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] }, { "ec_number": "5.6.1.7", "activity": "", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] } ] }, { "uniprot_ac": "Q2NL08", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", 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"bta:781444", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781444", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVKEKCK", "url": "https://omabrowser.org/oma/group/IVKEKCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZI1", "url": "https://www.orthodb.org/?gene=G3MZI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377219", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZI1", "url": "https://www.uniprot.org/uniprotkb/G3MZI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZI1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSISNITVFMPSVLTLIGIPGLESVQCWIGVPFCIMYLIAMIGNSLLLIIIKSEPSLHEPMYIFLGMLGVTDIALLTSVVPKMLGIFWFHIPEIYFDSCLLQMWLIHTFQGIESGILLAMALDRYVAVCYPLRHAAIFTPHLISQIASVVTLRAALLVAPCLVLIKFRLQFYHKTVISHSYCEHMAIVKLAAGNIQVNKIYGLFVAFNIAVFDLSFITLSYIQIFITVFRLPQKEARLKAFNTCIAHICVFLQFYFLAFFSFFAHRFGSHIPTFIHILISSIYLLVPPFLNPFIYGAKMKQIRIQMVKMFHS", "length": 312, "header": "tr|G3MZI1-1|G3MZI1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR52A1H PE=3 SV=1 CANONICAL=G3MZI1-1" }, "isoforms": [ { "isoform_ac": "G3MZI1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZI1/entry", "sequence": { "sequence": "MSISNITVFMPSVLTLIGIPGLESVQCWIGVPFCIMYLIAMIGNSLLLIIIKSEPSLHEPMYIFLGMLGVTDIALLTSVVPKMLGIFWFHIPEIYFDSCLLQMWLIHTFQGIESGILLAMALDRYVAVCYPLRHAAIFTPHLISQIASVVTLRAALLVAPCLVLIKFRLQFYHKTVISHSYCEHMAIVKLAAGNIQVNKIYGLFVAFNIAVFDLSFITLSYIQIFITVFRLPQKEARLKAFNTCIAHICVFLQFYFLAFFSFFAHRFGSHIPTFIHILISSIYLLVPPFLNPFIYGAKMKQIRIQMVKMFHS", "length": 312, "header": "tr|G3MZI1-1|G3MZI1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR52A1H PE=3 SV=1 CANONICAL=G3MZI1-1" }, "locus": { "chromosome": "15", "start_pos": 48541875, "end_pos": 48540940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063523.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063523.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054978.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054978.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:781444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781444", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3MZI1", "url": "https://www.uniprot.org/uniprotkb/G3MZI1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MZI1", "url": "https://www.uniprot.org/uniprotkb/G3MZI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MZI1", "url": "https://www.uniprot.org/uniprotkb/G3MZI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZI1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZI1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZI1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZI1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 295, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZJ5-1", "uniprot_ac": "G3MZJ5", "uniprot_id": "G3MZJ5_BOVIN", "mass": { "chemical_mass": 173079.0, "monoisotopic_mass": 173079.0 }, "refseq": { "ac": "XP_005218347", "name": "RIMS-binding protein 3A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218347" }, "gene_names": [ { "name": "RIMBP3B", "type": "recommended", "evidence": [ { "id": "G3MZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ] }, { "name": "RIMBP3B", "type": "synonym", "evidence": [ { "id": "XP_005218347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218347" } ] } ], "protein_names": [ { "name": "RIMS binding protein 3B", "type": "synonym", "evidence": [ { "id": "G3MZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5/entry#names_and_taxonomy" } ] }, { "name": "RIMS-binding protein 3A", "type": "synonym", "evidence": [ { "id": "XP_005218347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218347" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RIMBP3B", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000047538", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047538", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "528977", "url": "https://www.ncbi.nlm.nih.gov/gene/528977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528977", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528977", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQAFARQ", "url": "https://omabrowser.org/oma/group/CQAFARQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZJ5", "url": "https://www.orthodb.org/?gene=G3MZJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005218347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZJ5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKDSPSPADGGRAASQKPATPGPAAAALEEQRRELEKLRAELEAERARGRAERRRFSAGARQLREEAERERQQLADHLRSQWEAQRSRELRQLREDVLREREAEIRQLLRWKDAEMRQLQQVLRRERDGVARQARELQRQLAEELLSRGYGGGRAGPPEDAGARCRCRLQEVLSQLRWETHGEQASRIRHLEAALDVERRLFLKYILEHFHWHPALPSAPDAPLPLGEPTREAAAKARDGRSAGVRARSRSLDRVPAARARSPDSPLPTRASSLDSLAPAGPRPSLDGSPSHPRAPESSSPDASLSGSLRPLPPPPSPPPSERQIPSHLREGEEAGSRPCEALSPPPPGPDHCELLRRNSELSEALQELARRRCGLREENVRLRRLGLPDEADEKAKRLKGKRAELTGLARRLEDRARKLQEANLRAVSAPVPGESRPGLELCQALAHQRARDLSEQASALLAKDKQIEELRQERHLLRARVASGLGPLPGEGAASAQWLSIGDLDRLQRESQREVLRLQWQLTLQQAAGGARAEAGGQSAPCEAARRQVRALERELSARRQECEELGAQAAAAQRRGREAEAQLQVALREGAWLAKENARLQAQADWTRKVAAENEDVRGQLGRACQQRDSASLLAEQLLQQAAQRQDWQQQLQHDLQKVLCDLQAARDEMWALQCQPAHPPQDNRGTEPQLGPANPASPVPSRDKQGRKEDLLLESPAALGQPAWAPQAPDSSGQPLDSRPQPQRTGSQSNSSSEVESAWATVPSCPILDADTGSEAEDLEPDSLPSTLEAGDLEVSVATPKLKIFLARYSYNPFEEPSEHPESELPLTPGDHVYIFSDMDEDGFYEGALADGRQGLVPSNLVEQIPDGDIRGCLPTESPDRGPTWLPAARQGQAWKDDPSPGFLPGQAQAAVDRGPCPVARVGSRMEVATEVSDTKTEAGRLGSQESRDRQGSANAPPGNNRSPRMAPTHLHLRSVAATSAEVAWVGGSHAHAVYLDGREHALTSMGVSSYTFRHLQPGTRYQVRVEVRPPGDSLQACREKTSSAVTFETPLAGPPHPPLDVLVERHPSPGLLVVSWLPVTIDAAGSSNGVPVTGYAVYADGLKVADVAEATAGSTLLELSQLPWPETCQKISVRTTSLCGESLDSVPAQIPHDCFTCLHWPEMSPFGYTCRDPSAISGSFPVCPRRLGPTPLSAKACPHAPRSCEEPRARCLEAFPEEPPRRWSPEPKLISEGGGPSSGSGSQAQGPAEARKPPRKDQLFEKRPWNHRPPLPRGQPGREGTQDRRMLTVPTPAAGVSHLSPEPAPGEELRQEKPASGKVLRQKADALVSTPPELGSSQQSASVFSGARQEDGRGAEGRERRRALRGRSTQGQALGARAGGRLRGPSSAPCPARRSKALGTPRGAAPPPGTRVGPRAGIFVTLPNYEPLAVSATSEAAGGELALQKGQPQSAGGSQDPHGFCRGECSGPVGSITSHLVAEVDAGTECTDGHGRWHLPGHLDDSEGLTGPQGSSPLPQGSPGRPSSSLWAPKTMMAALDYDPQDWLARGPVKGQLSLRAGDVVTVHGPVDDKGFYSGEVGGHRGLVPAHLLGHMSLQE", "length": 1601, "header": "tr|G3MZJ5-1|G3MZJ5_BOVIN Isoform 1 of RIMS binding protein 3B OS=Bos taurus OX=9913 GN=RIMBP3B PE=3 SV=2 CANONICAL=G3MZJ5-1" }, "isoforms": [ { "isoform_ac": "G3MZJ5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5/entry", "sequence": { "sequence": "MSKDSPSPADGGRAASQKPATPGPAAAALEEQRRELEKLRAELEAERARGRAERRRFSAGARQLREEAERERQQLADHLRSQWEAQRSRELRQLREDVLREREAEIRQLLRWKDAEMRQLQQVLRRERDGVARQARELQRQLAEELLSRGYGGGRAGPPEDAGARCRCRLQEVLSQLRWETHGEQASRIRHLEAALDVERRLFLKYILEHFHWHPALPSAPDAPLPLGEPTREAAAKARDGRSAGVRARSRSLDRVPAARARSPDSPLPTRASSLDSLAPAGPRPSLDGSPSHPRAPESSSPDASLSGSLRPLPPPPSPPPSERQIPSHLREGEEAGSRPCEALSPPPPGPDHCELLRRNSELSEALQELARRRCGLREENVRLRRLGLPDEADEKAKRLKGKRAELTGLARRLEDRARKLQEANLRAVSAPVPGESRPGLELCQALAHQRARDLSEQASALLAKDKQIEELRQERHLLRARVASGLGPLPGEGAASAQWLSIGDLDRLQRESQREVLRLQWQLTLQQAAGGARAEAGGQSAPCEAARRQVRALERELSARRQECEELGAQAAAAQRRGREAEAQLQVALREGAWLAKENARLQAQADWTRKVAAENEDVRGQLGRACQQRDSASLLAEQLLQQAAQRQDWQQQLQHDLQKVLCDLQAARDEMWALQCQPAHPPQDNRGTEPQLGPANPASPVPSRDKQGRKEDLLLESPAALGQPAWAPQAPDSSGQPLDSRPQPQRTGSQSNSSSEVESAWATVPSCPILDADTGSEAEDLEPDSLPSTLEAGDLEVSVATPKLKIFLARYSYNPFEEPSEHPESELPLTPGDHVYIFSDMDEDGFYEGALADGRQGLVPSNLVEQIPDGDIRGCLPTESPDRGPTWLPAARQGQAWKDDPSPGFLPGQAQAAVDRGPCPVARVGSRMEVATEVSDTKTEAGRLGSQESRDRQGSANAPPGNNRSPRMAPTHLHLRSVAATSAEVAWVGGSHAHAVYLDGREHALTSMGVSSYTFRHLQPGTRYQVRVEVRPPGDSLQACREKTSSAVTFETPLAGPPHPPLDVLVERHPSPGLLVVSWLPVTIDAAGSSNGVPVTGYAVYADGLKVADVAEATAGSTLLELSQLPWPETCQKISVRTTSLCGESLDSVPAQIPHDCFTCLHWPEMSPFGYTCRDPSAISGSFPVCPRRLGPTPLSAKACPHAPRSCEEPRARCLEAFPEEPPRRWSPEPKLISEGGGPSSGSGSQAQGPAEARKPPRKDQLFEKRPWNHRPPLPRGQPGREGTQDRRMLTVPTPAAGVSHLSPEPAPGEELRQEKPASGKVLRQKADALVSTPPELGSSQQSASVFSGARQEDGRGAEGRERRRALRGRSTQGQALGARAGGRLRGPSSAPCPARRSKALGTPRGAAPPPGTRVGPRAGIFVTLPNYEPLAVSATSEAAGGELALQKGQPQSAGGSQDPHGFCRGECSGPVGSITSHLVAEVDAGTECTDGHGRWHLPGHLDDSEGLTGPQGSSPLPQGSPGRPSSSLWAPKTMMAALDYDPQDWLARGPVKGQLSLRAGDVVTVHGPVDDKGFYSGEVGGHRGLVPAHLLGHMSLQE", "length": 1601, "header": "tr|G3MZJ5-1|G3MZJ5_BOVIN Isoform 1 of RIMS binding protein 3B OS=Bos taurus OX=9913 GN=RIMBP3B PE=3 SV=2 CANONICAL=G3MZJ5-1" }, "locus": { "chromosome": "17", "start_pos": 72166771, "end_pos": 72161969, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064964.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064964.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054993.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054993.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1195, "start_aa": "Thr", "end_pos": 1195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:528977", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528977", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A7Z1-1", "protein_name": "RIMS binding protein 3", "gene_name": "Rimbp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKDSPTPLGGGRASPKKPGSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLREAAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAELRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQTTHSLEEPPLEAQSNTDGTPKPARRLGSLESLNTGVRVHSPNDLLPTRASSLESLATAHSCSLDNTLNCPETSESEVRAPSTTASIPDTSSPQPPPQLPSKHRKPNDLQKESSENKPCEDSTSSSPGLDYHELVRQNSELAEALQVLVRRCCDLREENLQLRRTGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPMPGESLEGLDLGQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADTGSPSAPSEIARHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHARQRQELEATGLLAEQLLQQEGYAQDRRQQLQQYQNKTPSDLRISGKEMQGLQFQPGHPSESSETTQASESQVRDSRRLKFKTKSEEYILPLPTRDIQPPACLSQQENPVALGEPAAASQVSDRNPSSQSLDSKLQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIVPKLKIFLARYSHNPFEGPSERSHDELPLTAGDYVYVFGDVDEDGFYEGELVNGQRGLVPSNLVEPISGSPILSHLFLKSPGAGPTSLPAEHSKALKKGSLLLGEVQERGLCQAGRVDSKTDVASESLKTKTEACWLGLKSSMEEQSFSRPLLEAKGALCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTRYQVRVGVQLPRDLLQVLWETMSSTVTFDTPLAGPPDPPLDVLVEHHAASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVANATAGNTLLELSQLQLPLGCQKVSVRTMSLYGESLDSVPAQIPEDCFSCYPFLEAPPFNYTDGDPFPVCHQKLAQASLSAKSSPHVPGSCGEPQAKFLEAFSEEQPRKHLSLSSLSSDGANKQVQGPTEAWKGYEKDLSFQRSPQNHKPPLLFGQSGVEEGHAPHICISGSPSPGFIHLSSEVGPGKILCWEEPGLEKALLQNQYAQMVPHHQQGSSQCHTADFHHIFEEKEALCLDSRCTEKPEQRKKSQNGQRQGTPGSKRECQFHEPTSVLCPAPTSKIIKIASGGSDQLETDGNSPVRVFLALFDHSPLARSVNSEATEEELSFQKGQLLRVWGSRDHHGFYHGECNGQVGKIPGHLVVEVEVGTQQTDGRWLLPPQGHLHSEAQREDLEGLTNSQGSYMLQGNSRTPTLWTPKTMVAALDYDPRDGRAGVRAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE", "length": 1612 }, "evidence": [ { "id": "G3MZJ5", "url": "https://omabrowser.org/oma/group/G3MZJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V0F0-1", "protein_name": "RIMS-binding protein 3", "gene_name": "Rimbp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDSPTPLGGGRASPKKPSSPGPAAAVLEEQRRELEKLRAELEGERARGRSERRRFATQTRQLRESAEQERQQLADHLRSKWEARRLRELRQLQEEVQREREAEIRQLLRWKEAEMRQLQQLLHQERDVVLRQARELQRQLAQELVNRGYCSRSGASEASAAQCRCRLQEVLALLRWETDGEQAARIRHLQAALDVERQLFLKYILEHFRWQPALPGPADPQATHSLEEPPLEAQSNTGGTPKPARRLGSLESLNTGVRVHSPNDLLPTRAGSLESLATAHSCSLDNTLNCSQASESEVRAPATSASIPDTSSPQPPPQLPSIHRKPNDLQKESSENKPCEASTSSPPGLDYQELVRQNSELAEALQVLVRRCCDLREENLHLRRKGFSEEAGEKVKWLKVKHAELTDLAQRLEDRARKLQETNLRAMSAPVPGESLEGLDLSQVFTCQRAQDLSEQAGALQAKDLQIEALRRECHLLQARIAADLGSSSHPEEGATCAQWCNISDLDRLQRESQREVLRLQRQLTLHQSKAGAWADAGRPSTPSEITRHQVQALERELGLQRRECEELSVQAAAAERRYEETEAQLQAALHKGARLSEENARLQALANWMKKMADENSNVSRQQSHTRQRQELEATSLLAEQLLQQEGYAQDRRQQLQHYKNKALSDLRTSGKEMQGLQFQPGHPSETSETTQASESQARDSGRPTFKTKSEERVLPLPTRDIQPPACLSQQENPVIVEEPAAGPQVSDRNSTSQSLDSKPQAKKTSSQSNSSSEVESMWATVPSCLSLDMDTASEVDDLEPDSMSTPLEMRSLEAPIIPKLKLFLARSSYNPFEGPSEHCQGKLPLTAGDYVYVFGDMDEDGFYEGELVNGQRGLVPSNLVEPISGSPILNHLFLKSPDIGPTALPAGHSKVLKKGSLLLGEVQERGLCQVGRVDSKTDMAAESLKTKTEACWLGLKSSLEEQSFSRPLLEAKGAFCLAPMELQLQNVTATSATITWASGSNRYPHVVYLDDEEHILTPSGVNHYTFQGLHPGTCYRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPPLDVLVEHHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVADATAGNTLLEFSQLQVPLSCQKVSVRTMSLYGESLDSVPAQIPEDFFSCCPFLGAPPFNYTDGNPFPVCHQKLVQASLGAKSSPRGPGNCGEPQAKFLEAFPEEHPRKHLSLSSLSSDGTNSQAQGPTEAWKGYEKDLSFQKSPQNHKPPLLFGQSGVEEGHAPHICISGSPAPGFVHLSSEIGHGKIRCWEKPGLEKALLQNQYAPMVPPHQQGSSQCQPADFHHVFEEKEALCLDSQGTEKPEQRKNKSQNGQRQGTPGSKRECSVLCPAPTNKVIKMTSGSPDQLETDANNPVRVFLALFDHSPLVISVNSEAAEEELAFQKGQLLRVWGSLDLHGFYHGECNGHLGKIPGHLVVEVEVGTQQTDGRWHLPAQGHLLSETQREDLEGLTNSQGSYMPQGNSRTPTLWTPKTMVAALDYDPRDGRAGVQAKGKLVLRAGDVVTVYGPVDDKGFYYGEYGGHRGLVPAHLLDDLPVHGE", "length": 1606 }, "evidence": [ { "id": "G3MZJ5", "url": "https://omabrowser.org/oma/group/G3MZJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UFD9-1", "protein_name": "RIMS-binding protein 3A", "gene_name": "RIMBP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQAENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARKLQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGAQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELEDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGVVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRARVEVRLPRDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTLLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCSQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLWGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGNLPSVAHLEDFQGLTIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "G3MZJ5", "url": "https://omabrowser.org/oma/group/G3MZJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "benzodiazepine receptor binding", "id": "GO:0030156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030156", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ5", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 971, "end_pos": 1057, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MZJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZJ5" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 804, "end_pos": 871, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1195 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 754, "end_pos": 756 }, { "start_pos": 965, "end_pos": 967 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, 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"id": "G3MZM3", "url": "https://www.uniprot.org/uniprotkb/G3MZM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZM3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASCLVPALLLLLLLGSRSSVAPNPCVDAADACTADERCHRLRTAYVAQCLGRAAPEGCPRARCRRALRHFFARGPPALTHALLFCPCGGPACAERRRQTFVPSCAFSGPGRAPPSCLGPLDACEHSRICRPRLLAFQVSCATTASNPDGCLRDQAPSCLRAYAGLVGTAITPNYVDNASARVEPWCDCRASGNRREECEVFRGLFTRNRCLDSAIQTFDGGWPPILRNQLDSHQDPEQSLLQVSTADAPLEESSLLSMLLVLALQSLF", "length": 269, "header": "tr|G3MZM3-1|G3MZM3_BOVIN Isoform 1 of GDNF family receptor alpha 4 OS=Bos taurus OX=9913 GN=GFRA4 PE=3 SV=3 CANONICAL=G3MZM3-1" }, "isoforms": [ { "isoform_ac": "G3MZM3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZM3/entry", "sequence": { "sequence": "MASCLVPALLLLLLLGSRSSVAPNPCVDAADACTADERCHRLRTAYVAQCLGRAAPEGCPRARCRRALRHFFARGPPALTHALLFCPCGGPACAERRRQTFVPSCAFSGPGRAPPSCLGPLDACEHSRICRPRLLAFQVSCATTASNPDGCLRDQAPSCLRAYAGLVGTAITPNYVDNASARVEPWCDCRASGNRREECEVFRGLFTRNRCLDSAIQTFDGGWPPILRNQLDSHQDPEQSLLQVSTADAPLEESSLLSMLLVLALQSLF", "length": 269, "header": "tr|G3MZM3-1|G3MZM3_BOVIN Isoform 1 of GDNF family receptor alpha 4 OS=Bos taurus OX=9913 GN=GFRA4 PE=3 SV=3 CANONICAL=G3MZM3-1" }, "locus": { "chromosome": "13", "start_pos": 51531017, "end_pos": 51526996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066172.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066172.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055024.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055024.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-BTA-8853659", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8853659", "resource": "Reactome", "description": "RET signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "G3MZM3", "url": "https://www.uniprot.org/uniprotkb/G3MZM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "G3MZM3", "url": "https://www.uniprot.org/uniprotkb/G3MZM3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "G3MZM3", "url": "https://www.uniprot.org/uniprotkb/G3MZM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glial cell-derived neurotrophic factor receptor activity", "id": "GO:0016167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016167", "evidence": [ { "database": "UniProtKB", "id": "G3MZM3", "url": "https://www.uniprot.org/uniprotkb/G3MZM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZM3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 269, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZM3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZM3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZM3" }, { "id": "SM00907", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00907" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GDNF/GAS1", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 105, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"uniprot_canonical_ac": "G3MZN6-1", "uniprot_ac": "G3MZN6", "uniprot_id": "G3MZN6_BOVIN", "mass": { "chemical_mass": 85283.0, "monoisotopic_mass": 85283.0 }, "refseq": { "ac": "XP_024850982", "name": "PH and SEC7 domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850982" }, "gene_names": [ { "name": "PSD2", "type": "recommended", "evidence": [ { "id": "G3MZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ] }, { "name": "PSD2", "type": "synonym", "evidence": [ { "id": "XP_024850982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850982" } ] } ], "protein_names": [ { "name": "PH and SEC7 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_024850982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850982" } ] }, { "name": "Pleckstrin and Sec7 domain containing 2", "type": "synonym", "evidence": [ { "id": "G3MZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZN6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PSD2", "url": "https://www.uniprot.org/uniprotkb/G3MZN6", "locus": { "chromosome": "7", "start_pos": 51026722, "end_pos": 50954924, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000238", "url": "https://www.ensembl.org/id/ENSBTAG00000000238" } ] } } ], "crossref": [ { "id": "G3MZN6", "url": "https://alphafold.ebi.ac.uk/entry/G3MZN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000238", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13295", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13295", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "523045", "url": "https://www.ncbi.nlm.nih.gov/gene/523045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523045", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKETHDK", "url": "https://omabrowser.org/oma/group/PKETHDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHH5", "url": "https://www.orthodb.org/?gene=E1BHH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZN6", "url": "https://www.orthodb.org/?gene=G3MZN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024850982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BHH5", "url": "https://www.uniprot.org/uniprotkb/E1BHH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZN6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEDTLLSTLPGEDGATWDPSLEPEEEPGVQNGMASSEDLNSSHTSPGHAMRGPLAGTEGHTKGLDVALHGLSLGLSLTNGLALGPDSNVLEHSTDPRPWRAGGLAEGDDASRSLCPDTEDPPLGPGGPGEPDVRDGFSATFEKIVESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPELGAGLGTGDMGSEGDMGAAGGGGVLGSPLRRSISGSRSENVLSRLSLTAVPNGFHEDGPLGPRGDEEDDEEEEEEEEDTDKLLNSASDPSLKDGLSDSDSELSSSEGLESGSTDPLANGGQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGSNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPSFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQVTAELAEHKCHPVERGIKSKEAEENRLKEHYLTFEKSRYETYIHLLAVKIKVGSDDLERIEARLATLEGDDPSLRKTHSSPALSQGHGTVTGSKAMRDTTGPDT", "length": 780, "header": "tr|G3MZN6-1|G3MZN6_BOVIN Isoform 1 of Pleckstrin and Sec7 domain containing 2 OS=Bos taurus OX=9913 GN=PSD2 PE=4 SV=3 CANONICAL=G3MZN6-1" }, "isoforms": [ { "isoform_ac": "E1BHH5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHH5/entry", "sequence": { "sequence": "MDEDTLLSTLPGEDGATWDPSLEPEEEPGVQNGMASSEDLNSSHTSPGHAMRGPLAGTEGHTKGLDVALHGLSLGLSLTNGLALGPDSNVLEHSTDPRPWRAGGLAEGDDASRSLCPDTEDPPLGPGGPGEPDVRDGFSATFEKIVESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPELGAGLGTGDMGSEGDMGAAGGGGVLGSPLRRSISGSRSENVLSRLSLTAVPNGFHEDGPLGPRGDEEDDEEEEEEEEDTDKLLNSASDPSLKDGLSDSDSELSSSEGLESGSTDPLANGGQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGSNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPSFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQVTAELAEHKCHPVERGIKSKEAEENRLKEHYLTFEPGTPSLGALHFGGSPEVMNCSHL", "length": 734, "header": "tr|E1BHH5-1|E1BHH5_BOVIN Computationally mapped isoform of Pleckstrin and Sec7 domain containing 2 OS=Bos taurus OX=9913 GN=PSD2 PE=4 SV=4 CANONICAL=G3MZN6-1" }, "locus": { "chromosome": "7", "start_pos": 51019362, "end_pos": 50988391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000293.8", "url": "https://www.ensembl.org/id/ENSBTAT00000000293.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000293.7", "url": "https://www.ensembl.org/id/ENSBTAP00000000293.7" } ] } }, { "isoform_ac": "G3MZN6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZN6/entry", "sequence": { "sequence": "MDEDTLLSTLPGEDGATWDPSLEPEEEPGVQNGMASSEDLNSSHTSPGHAMRGPLAGTEGHTKGLDVALHGLSLGLSLTNGLALGPDSNVLEHSTDPRPWRAGGLAEGDDASRSLCPDTEDPPLGPGGPGEPDVRDGFSATFEKIVESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPELGAGLGTGDMGSEGDMGAAGGGGVLGSPLRRSISGSRSENVLSRLSLTAVPNGFHEDGPLGPRGDEEDDEEEEEEEEDTDKLLNSASDPSLKDGLSDSDSELSSSEGLESGSTDPLANGGQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGSNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPSFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQVTAELAEHKCHPVERGIKSKEAEENRLKEHYLTFEKSRYETYIHLLAVKIKVGSDDLERIEARLATLEGDDPSLRKTHSSPALSQGHGTVTGSKAMRDTTGPDT", "length": 780, "header": "tr|G3MZN6-1|G3MZN6_BOVIN Isoform 1 of Pleckstrin and Sec7 domain containing 2 OS=Bos taurus OX=9913 GN=PSD2 PE=4 SV=3 CANONICAL=G3MZN6-1" }, "locus": { "chromosome": "7", "start_pos": 51025718, "end_pos": 50988391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064724.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064724.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055038.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055038.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:523045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523045", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YJM9-1", "protein_name": "Pleckstrin and Sec7 domain containing 2", "gene_name": "PSD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSESRHFPLSVAARSELHSSGSQPTVQAHSDGDEQLGQPAEPASGRASPLDDAEPSPSADEEHHGDQHLAASTGEWEQEVHATSNSEGCKELALTNGVDVELGAGGEEVRLQPPDGSVPSPGSVDSGEEGSPGPQARSQALSKVLLHGFLGSAGALSADEPEEQLGFAAGDAKLSCSEDDKEHFQFKDIRDGFSSTFEKIVESDLMKGTYYSSLDSLDVLSLTDETDSCVSFEAPLTPLIQQRVKESPELLEQKLVAQQRESPHHMVADKQEQAAAKPAEVDFGSPLRHSITSSRSENVLSRLSLKNIPNGFHVEGSEEDATKIINSISDASLKDALSDSDSDMGSTEQLDQGSTDTLANGCRADSEAAKRLAKRLYNLEGFKRCDVARQLGKNNEFSKLVAEEYLSFFDFTGLTLDKALRTFLKAFPLMGETQERERVLIHFSRRYCQCNPEESTSEDGVHTLTCALMLLNTDLHGHVNIGKKMSCQQFITNLDGLNDGKDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGASAKKVTRIVDSSNPFLDIPQALNAVTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYKPDKDLSEVDLKNAIRVHHALATKASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAICSMKKFCRPLLPSSMTKLCQEEQLRSHENKMKQIADELAEHKSHPVEKSLKSKEAEEYRLKEHYLIFEKSRYETYINLLCMKIKVGTDDLERIETSFFKVEADDIALRKTHSSPSLSQGHMSVSCKVEKDIIEQNT", "length": 828 }, "evidence": [ { "id": "G3MZN6", "url": "https://omabrowser.org/oma/group/G3MZN6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACB6-1", "protein_name": "Pleckstrin and Sec7 domain containing 2", "gene_name": "Psd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEEKLPSDLHKEEGAIQDHSLEPEEGPGVQNGTAASESLNSHVISPVSEKTGTLEGTMEPVGNPDVALPGLSLSLTNGLALGQDGNILEDSVESRPWRASGPAEEEDTPRSLCLDAEDTQLGLDCPGEPDVRDGFSATFEKILESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPEPAGLGIGDIGPEGDLGAAGGGDGELGSPLRRSISSSRSENVLSHLSLTSMPNGFHEDEPGGSGGDDEDDEDTDKVLNSASDTSLKDGLSDSDSELSSSEGLEPGSTDPMANGCQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHVNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLLPSCTTRFCQEEQLRSHENKLRQVTAELAEHRCHPLERGLKSKEAEEYRLKEHYLTFEKSRYETYIHLLAVKIKVGSDDLERIEARLATLEGEDPALRKTHSSPALSLGHGPVTGSKAAKDASASDT", "length": 772 }, "evidence": [ { "id": "G3MZN6", "url": "https://omabrowser.org/oma/group/G3MZN6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P1I6-1", "protein_name": "PH and SEC7 domain-containing protein 2", "gene_name": "Psd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEEKLPCELHKEGSATQEDHGLEPEEEPGLQNGTAASEGLSSHISGPGGEKTLEGTMEPVRGPDVALPGLNLSLTNGLALGQDGNILEDSIEFKTWRSGPAEEEDVPGSPCPDAGDPQLGLDCPGEPDVRDGFSATFEKILESELLRGTQYSSLDSLDVLSLTDESDSCVSFEAPLTPLIQQRARDSPEAGAGLGNGDMGPEGDLGATGGCDGELGSPLRRSISSSRSENVLSHLSLTSVPNGFHEDGPGGSGGDDEDDEDTDKLLNSASDTSLKDGLSDSDSELSSSEGLEPGSTDPLANGCQGVSEAARRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDRALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALNATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRLDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQVTAELAEHRCHPLERGLKSKEAEEYRLKEHYLTFEKSRYETYIHLLAVKIKVGSDDLERIEARLATIEGDDPALRKTHSSPALSLGHGPVTGSKATKDTSASDT", "length": 770 }, "evidence": [ { "id": "G3MZN6", "url": "https://omabrowser.org/oma/group/G3MZN6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQI7-1", "protein_name": "PH and SEC7 domain-containing protein 2", "gene_name": "PSD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDKLLSAVPEEGDATRDPGPEPEEEPGVRNGMASEGLNSSLCSPGHERRGTPADTEEPTKDPDVAFHGLSLGLSLTNGLALGPDLNILEDSAESRPWRAGVLAEGDNASRSLYPDAEDPQLGLDGPGEPDVRDGFSATFEKILESELLRGTQYSSLDSLDGLSLTDESDSCVSFEAPLTPLIQQRARDSPEPGAGLGIGDMAFEGDMGAAGGDGELGSPLRRSISSSRSENVLSRLSLMAMPNGFHEDGPQGPGGDEDDDEEDTDKLLNSASDPSLKDGLSDSDSELSSSEGLEPGSADPLANGCQGVSEAAHRLARRLYHLEGFQRCDVARQLGKNNEFSRLVAGEYLSFFDFSGLTLDGALRTFLKAFPLMGETQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKKMSCQQFIANLDQLNDGQDFAKDLLKTLYNSIKNEKLEWAIDEDELRKSLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALSATTYKHGVLTRKTHADMDGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSEGDLKNAIRVHHALATRASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLLPSCTTRLCQEEQLRSHENKLRQLTAELAEHRCHPVERGIKSKEAEEYRLKEHYLTFEKSRYETYIHLLAMKIKVGSDDLERIEARLATLEGDDPSLRKTHSSPALSQGHVTGSKTTKDATGPDT", "length": 771 }, "evidence": [ { "id": "G3MZN6", "url": "https://omabrowser.org/oma/group/G3MZN6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "G3MZN6", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZN6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 780, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZN6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZN6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 519, "end_pos": 632, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MZN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZN6" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 266, "end_pos": 469, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZP0-1", "uniprot_ac": "G3MZP0", "uniprot_id": "G3MZP0_BOVIN", "mass": { "chemical_mass": 67918.0, "monoisotopic_mass": 67918.0 }, "refseq": {}, "gene_names": [ { "name": "CATSPER4", "type": "recommended", "evidence": [ { "id": "G3MZP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ] } ], "protein_names": [ { "name": "Cation channel sperm associated 4", "type": "synonym", "evidence": [ { "id": "G3MZP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CATSPER4", "url": "https://www.uniprot.org/uniprotkb/G3MZP0", "locus": { "chromosome": "2", "start_pos": 126895788, "end_pos": 126911447, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000026638", "url": "https://www.ensembl.org/id/ENSBTAG00000026638" } ] } } ], "crossref": [ { "id": "G3MZP0", "url": "https://alphafold.ebi.ac.uk/entry/G3MZP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000026638", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026638", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MZP0", "url": "https://www.orthodb.org/?gene=G3MZP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47077", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47077", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47077:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47077:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1300642", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1300642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZP0-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLHVPLTSVLESGICFWEGTGMKSCQMGVNALALRDLMVLSCAISRGEHGLTSSSWMQSRDLPLCLHPGCVRDLTCSHQPPTCDLPRVLGLLCGTPRGVSGRSFSCSRSSLVECGRWGVTEASVISPRGAGRRAWSDVSLRSRGRLSDMADNQRSWWQQWTDTTYIRPLNRLRAAQEPYRRPEEQVLINRRDITSRKDAWDMQEFITRMYVKQLLRHPASKVLLAMLLVVNAITIALRTNSMLGQKHYELFSTIDDIVLTTLICELLLGWLNGFWIFWKDGWNILNFLIIFILLLGFFVNELSVVAITYTLRALRLLHVCMAVEPLARIIRVILKSVPDMANIMVLILFLMLVFSVFGVTLFGVFVPMHFQNMQVALYTLFICITQDGWVDIYSDFQTETGEYGVEIGGAIYFAIFITIGAFIGINLLVVVVTTNLEQMMKAEQGHQHQIAFREVNDKKENGNNKLPLVHCAVARSEMSGVPQEPFMGGPLTNLSERTCDNFCLVLEAIQENLMEYKEIRDELNMIVDEVRSIRFNQEQEEELMQRYLSWNISLESRSSVDIREMTREQDLITALVNREKVQESNTNINKHKASR", "length": 596, "header": "tr|G3MZP0-1|G3MZP0_BOVIN Isoform 1 of Cation channel sperm associated 4 OS=Bos taurus OX=9913 GN=CATSPER4 PE=4 SV=3 CANONICAL=G3MZP0-1" }, "isoforms": [ { "isoform_ac": "G3MZP0-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP0/entry", "sequence": { "sequence": "MNLHVPLTSVLESGICFWEGTGMKSCQMGVNALALRDLMVLSCAISRGEHGLTSSSWMQSRDLPLCLHPGCVRDLTCSHQPPTCDLPRVLGLLCGTPRGVSGRSFSCSRSSLVECGRWGVTEASVISPRGAGRRAWSDVSLRSRGRLSDMADNQRSWWQQWTDTTYIRPLNRLRAAQEPYRRPEEQVLINRRDITSRKDAWDMQEFITRMYVKQLLRHPASKVLLAMLLVVNAITIALRTNSMLGQKHYELFSTIDDIVLTTLICELLLGWLNGFWIFWKDGWNILNFLIIFILLLGFFVNELSVVAITYTLRALRLLHVCMAVEPLARIIRVILKSVPDMANIMVLILFLMLVFSVFGVTLFGVFVPMHFQNMQVALYTLFICITQDGWVDIYSDFQTETGEYGVEIGGAIYFAIFITIGAFIGINLLVVVVTTNLEQMMKAEQGHQHQIAFREVNDKKENGNNKLPLVHCAVARSEMSGVPQEPFMGGPLTNLSERTCDNFCLVLEAIQENLMEYKEIRDELNMIVDEVRSIRFNQEQEEELMQRYLSWNISLESRSSVDIREMTREQDLITALVNREKVQESNTNINKHKASR", "length": 596, "header": "tr|G3MZP0-1|G3MZP0_BOVIN Isoform 1 of Cation channel sperm associated 4 OS=Bos taurus OX=9913 GN=CATSPER4 PE=4 SV=3 CANONICAL=G3MZP0-1" }, "locus": { "chromosome": "2", "start_pos": 126911248, "end_pos": 126896200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063395.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063395.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055042.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055042.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1300642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1300642", "resource": "Reactome", "description": "Sperm Motility And Taxes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "CatSper complex", "id": "GO:0036128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036128", "evidence": [ { "database": "UniProtKB", "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "G3MZP0", "url": "https://www.uniprot.org/uniprotkb/G3MZP0" } ], "pmid": "" } 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"start_pos": 552, "end_pos": 554 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZP2-1", "uniprot_ac": "G3MZP2", "uniprot_id": "G3MZP2_BOVIN", "mass": { "chemical_mass": 24503.0, "monoisotopic_mass": 24503.0 }, "refseq": { "ac": "XP_059745561", "name": "GTP-binding nuclear protein Ran-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745561" }, "gene_names": [ { "name": "LOC132346044", "type": "recommended", "evidence": [ { "id": "G3MZP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP2" } ] }, { "name": "LOC132346044", "type": "synonym", "evidence": [ { "id": "XP_059745561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745561" } ] } ], "protein_names": [ { "name": "GTP-binding nuclear protein Ran", "type": "recommended", "evidence": [ { "id": "G3MZP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP2/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding nuclear protein Ran-like", "type": "synonym", "evidence": [ { "id": "XP_059745561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745561" } ] } ], "function": [ { "annotation": "GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.", "evidence": [ { "database": "UniProtKB", "id": "G3MZP2", "url": "https://www.uniprot.org/uniprotkb/G3MZP2#function" }, { "database": "UniProtKB", "id": "RU363057", "url": "https://www.uniprot.org/uniprotkb/RU363057#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZP2", "url": "https://www.uniprot.org/uniprotkb/G3MZP2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132346044", "url": "https://www.uniprot.org/uniprotkb/G3MZP2", "locus": {} } ], "crossref": [ { "id": "G3MZP2", "url": "https://alphafold.ebi.ac.uk/entry/G3MZP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024233", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024233", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00877", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00877", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "132346044", "url": "https://www.ncbi.nlm.nih.gov/gene/132346044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:132346044", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132346044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24071:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24071:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059745561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MZP2", "url": "https://www.uniprot.org/uniprotkb/G3MZP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZP2-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAAQGEPQVQFKLVLVGDGGTGKTTFVKRRLTGEFEKKYVATLGVEVHPLVFHTNRGQIKFTVWDTAGQEKFGGLRDGYYIQAQCAVIMFDVTSRVTYKNVPNWHRDLVRVWEDIPTVLCGNKVDIKDKKVKAKSIVFHRKKNLQYYDISAKSNYSFEKPFFLLARKLIGDPNLEFVAVSALAPPEVVMDLALAARYEHDSEAAQTTALPDEDDDL", "length": 217, "header": "tr|G3MZP2-1|G3MZP2_BOVIN Isoform 1 of GTP-binding nuclear protein Ran OS=Bos taurus OX=9913 GN=LOC132346044 PE=3 SV=3 CANONICAL=G3MZP2-1" }, "isoforms": [ { "isoform_ac": "G3MZP2-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP2/entry", "sequence": { "sequence": "MMAAQGEPQVQFKLVLVGDGGTGKTTFVKRRLTGEFEKKYVATLGVEVHPLVFHTNRGQIKFTVWDTAGQEKFGGLRDGYYIQAQCAVIMFDVTSRVTYKNVPNWHRDLVRVWEDIPTVLCGNKVDIKDKKVKAKSIVFHRKKNLQYYDISAKSNYSFEKPFFLLARKLIGDPNLEFVAVSALAPPEVVMDLALAARYEHDSEAAQTTALPDEDDDL", "length": 217, "header": "tr|G3MZP2-1|G3MZP2_BOVIN Isoform 1 of GTP-binding nuclear protein Ran OS=Bos taurus OX=9913 GN=LOC132346044 PE=3 SV=3 CANONICAL=G3MZP2-1" }, "locus": { "chromosome": "8", "start_pos": 54665071, "end_pos": 54664421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033457.6", "url": "https://www.ensembl.org/id/ENSBTAT00000033457.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055044.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055044.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:132346044", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132346044", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "G3MZP2", "url": "https://www.uniprot.org/uniprotkb/G3MZP2" 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"evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ] }, { "name": "CMTR2", "type": "synonym", "evidence": [ { "id": "XP_002694893", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694893" } ] } ], "protein_names": [ { "name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "type": "recommended", "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.296", "type": "synonym", "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6/entry#names_and_taxonomy" } ] }, { "name": "Cap methyltransferase 2", "type": "synonym", "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6/entry#names_and_taxonomy" } ] }, { "name": "Cap2 2'O-ribose methyltransferase 2", "type": "synonym", "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6/entry#names_and_taxonomy" } ] }, { "name": "FtsJ methyltransferase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6/entry#names_and_taxonomy" } ] }, { "name": "cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "type": "synonym", "evidence": [ { "id": "XP_002694893", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694893" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.", "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6#function" }, { "database": "UniProtKB", "id": "ARBA00059552", "url": "https://www.uniprot.org/uniprotkb/ARBA00059552#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CMTR2", "url": "https://www.uniprot.org/uniprotkb/G3MZP6", "locus": { "chromosome": "18", "start_pos": 39771057, "end_pos": 39666317, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047367", "url": "https://www.ensembl.org/id/ENSBTAG00000047367" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047367", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047367", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "781914", "url": "https://www.ncbi.nlm.nih.gov/gene/781914", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:781914", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781914", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WCIPDPN", "url": "https://omabrowser.org/oma/group/WCIPDPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZP6", "url": "https://www.orthodb.org/?gene=G3MZP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16121:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16121:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002694893", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694893", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "67024", "url": "https://www.rhea-db.org/rhea/67024", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZP6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKCRKQPLGSSPETFSPDVLADIFELFAKNFSYGKPLNNEWQLPDPSEIFTCDHTEFSAFLDLKNSLNEVKNLLSDKKLDEWHEHTAFTNKAGKIISHVRKSVNAELCTQAWCKFHEILCSFPLIPQEAFQNGKLNSLHLCEAPGAFIASLNHYLKSHRFPCDWNWVANTLNPYHEANDNLTMIMDDRLIANTLHCWYFGPDNTGDIMTLKYLTGLQNFINSMGTIHLITADGSFDCQGNPGEQEALVSCLHYCEAVTALMTLGNGGSFVLKMFTLFEHCSINLMYLLNCSFDQVHIFKPATSKAGNSEVYVVCLYYKGRETIYPILSKMVLNFGSEMTKKALFPHHMIPESFLRKHEECCTFFHKYQLETISENIRLFECMGKREQAKLNSLRDYAVQYFMQKFQLKPLSRNNWLVKKSNIGCSTNTKWFGQRSRYFKTYNERKMLETLSWKDKVAKGYFNSWAEEHATYHPGQSSLLEGTAFNLECHLWQVLQGKKLPKVKCSPFCDGEILKALNESVEKSLGGALNFDLKFRPKQKHCCSCHVFSEELIFSELFSLTKCLQDHQDKEPSTQIKCLLVGFPALHNIKMPIPLEVRLLESAALMTFSCSLLHDGDPTYQQLFLDCVLHSLQQLHTGDVMILPILSCFTRFMAGLIFVLHSCFRFITFSCPISSEPLKTCAVLLCVGYQDLPNPVFQYLQNVNELLRDLVNTEAPQQVLQFVPMEVLLKGALLDFLWDLNAAIAKRYLHLIIQGEREEIIGSL", "length": 764, "header": "tr|G3MZP6-1|G3MZP6_BOVIN Isoform 1 of Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 OS=Bos taurus OX=9913 GN=CMTR2 PE=4 SV=1 CANONICAL=G3MZP6-1" }, "isoforms": [ { "isoform_ac": "G3MZP6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP6/entry", "sequence": { "sequence": "MNKCRKQPLGSSPETFSPDVLADIFELFAKNFSYGKPLNNEWQLPDPSEIFTCDHTEFSAFLDLKNSLNEVKNLLSDKKLDEWHEHTAFTNKAGKIISHVRKSVNAELCTQAWCKFHEILCSFPLIPQEAFQNGKLNSLHLCEAPGAFIASLNHYLKSHRFPCDWNWVANTLNPYHEANDNLTMIMDDRLIANTLHCWYFGPDNTGDIMTLKYLTGLQNFINSMGTIHLITADGSFDCQGNPGEQEALVSCLHYCEAVTALMTLGNGGSFVLKMFTLFEHCSINLMYLLNCSFDQVHIFKPATSKAGNSEVYVVCLYYKGRETIYPILSKMVLNFGSEMTKKALFPHHMIPESFLRKHEECCTFFHKYQLETISENIRLFECMGKREQAKLNSLRDYAVQYFMQKFQLKPLSRNNWLVKKSNIGCSTNTKWFGQRSRYFKTYNERKMLETLSWKDKVAKGYFNSWAEEHATYHPGQSSLLEGTAFNLECHLWQVLQGKKLPKVKCSPFCDGEILKALNESVEKSLGGALNFDLKFRPKQKHCCSCHVFSEELIFSELFSLTKCLQDHQDKEPSTQIKCLLVGFPALHNIKMPIPLEVRLLESAALMTFSCSLLHDGDPTYQQLFLDCVLHSLQQLHTGDVMILPILSCFTRFMAGLIFVLHSCFRFITFSCPISSEPLKTCAVLLCVGYQDLPNPVFQYLQNVNELLRDLVNTEAPQQVLQFVPMEVLLKGALLDFLWDLNAAIAKRYLHLIIQGEREEIIGSL", "length": 764, "header": "tr|G3MZP6-1|G3MZP6_BOVIN Isoform 1 of Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 OS=Bos taurus OX=9913 GN=CMTR2 PE=4 SV=1 CANONICAL=G3MZP6-1" }, "locus": { "chromosome": "18", "start_pos": 39769180, "end_pos": 39766889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133197.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133197.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084731.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084731.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:781914", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781914", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4N5-1", "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "gene_name": "CMTR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNKCRKPPLGSSPETFSPDILADIFELFAKNFSYGKSPNNEWQLPDPSELFTCDHMEFNAFLDLKNSLNEVKNLLSDKKLDEWHEHTAFTNKAGKIISHVRKSVNAELCTQAWCKFHEILCSFPLVPQEAFQNGKLNSLHLCEAPGAFIASLNHYLKSHRFPCEWNWVANTLNPYHEANDNLMMIMDDRLIANTLHCWYFGPDNTGDIMTVKYLTGLQNFISSMATVHLITADGSFDCQGNPGEQEALVSSLHYCEVVTALMTLGNGGSFVLKMFTLFEHCSINLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLCYKGREAVDPLLSKMVLNFGSEMTRKALFPHHLIPESFLKRHEECCVFFHKYQLETISENIRLFECMGKGEQAKLNSLRDYAVQYFMQKFQLKPLSRNNWLVKKSNIGCSTNTKWFGQRNRYFKTYNERKMLETLSWKDKVAKGYFNSWAEEHVEYHPGQSSVLEGTASNLECHLWQILQGKKLPKVKCSPFCDGEILKALNEAVEKSLGGALNLDSKLKPKQQYCSCHVFSEELIFSELFSLTKCLQDEQDVEPSNHIKCLLVGFPTFHDIKMRMPLEVHLLESAELMTCSCSLLHDGDPAYQQLFLDCLLHSLQQLRVGDVMILPILSCFTRFMAGLIFVLHSCFRFITFSCPVSSEPLNTCAVLLCVGYQDLPNPVFQYLQHVNELLGASVNSDTPQQVLQFVPMEVLLKGSLLDFLWDLNAAIAKRHLHLIIQGEREEISSLQL", "length": 764 }, "evidence": [ { "id": "G3MZP6", "url": "https://omabrowser.org/oma/group/G3MZP6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z980-1", "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "gene_name": "Cmtr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKRRKRPAQQPASPETFSPDALNAVSELFAKNFSYCKPLDHEWQLPAPAESFTCEHVEFQAFLDLKNSLNAVKNLLCDKELDGWHRHTAFTNRAGQIIAHVRKAVNAELCTQAWCKFQEILCSFPLIPQEAFQSGRLNSLHLCEAPGAFIASLNHYLKSHRFPCEWSWVANSLNPYHEANDNLRMITDDRLIANTLHRWYFGPDNTGDIMTLKYLTGLQDFLSGTSPIHLVTADGSFDCQGNPGEQEALVSPLHYCEAVTALTTLGDGGSFVLKMFTLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLCYKGREAIRPLLSRMVLNFGTEMTKKALFPHHVIPKSFLERHRECCTLFHRYQLETISENIRLFECMGTGEQEKLNNLRNCAVQHFMQKFQLKPLSRNHWLVKKSTLGCSTNTKWFGQRNKYFRTYNERKMLETLSWKDKVARGFFDSWAEEHVVYHPGQSPLLEGSASSLECHLWCILEGKKLPKVKCSPFCDSEILKTLNEAIEKSSGEALSVESKVSPKQQYRCCQIFSEESVLSELLSLTKCLQEEQGVEPSNPIRCLLVGSPTVRDLQMYTALEVQLLESVELTAFSCSLLHDGDPAYQHLFLNCLLHSLKQLHSGDVMILPILSCFTRFMAGLTFVLHSCFRFITFSCPTSSEPLRTCAVLLCIGYQNLPDPVFQFLQNVNELLGTLLHPGAPQQVLQFVPMEVLLQGTLLDFLWDLNAAIAKRHLHLIIQGERDKVISSLEL", "length": 767 }, "evidence": [ { "id": "G3MZP6", "url": "https://omabrowser.org/oma/group/G3MZP6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BWQ4-1", "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "gene_name": "Cmtr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKRRKLPARQPACLETFSPDVLNDVSELFAKSFSYRKPLDNEWQLPAPTESFSCGHLEFRALLDLKNSLNEVKNLLSDKKLDEWHRHTAFTNKAGKIISHVKKAVNAELCTQAWCKFQEILCSFPLIPQEAFQSGRLNSLHLCEAPGAFIASLNHYLKSHRFPCEWSWVANSLNPYHEANDNLRMITDDRLMANTLHCWYFGPDNTGDIMTLKYLTGLQDFLSGMSPIHLVTADGSFDCQGNPGEQEALVSSLHYCEAVTALITLGDGGSFVLKMFTLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLRYKGREAVQPLLSRMVLNFGTEMTRKALFPHHVIPKSFLERHEECCTFFHRYQLETISENIRLFESMGTGEQERLNNLRDCAVQYFMQKFQLKPLSRNHWLVKKSNIGCSMNTKWFGQRNKYFKTYNERKMMETLSWKDKVAKGYFNSWAEEHTVYHPGQNSLLEGTASSLEYQSWQVLEGKKLPKVKCSPFCDGEILKTLNEAIEKSLGEALSVDAKVSSKQQYRCCPVFSEESVLSELLRLTKCLPDEQGAEPSGPVKCLLVGSPAVCDLQMPAPLEIQLVESVELTAFSCSLLHDGDPAYQHLFLDCLLHSLRRLHRGDVMVLPILSCFTRFMAGLTFVLHGCFRFITFSCPTSLEPLRTCAVLLCIGYQNLPDAVFQFLQNVHDLLSKLLHPSAPRQILQFLPMEALLQGTLLDFLWDLNAAIAKRHLHLIIQGERDQAIGSLEL", "length": 767 }, "evidence": [ { "id": "G3MZP6", "url": "https://omabrowser.org/oma/group/G3MZP6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYT2-1", "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "gene_name": "CMTR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKCRKTPVQQLASPASFSPDILADIFELFAKNFSYGKPLNNEWQLPDPSEIFTCDHTELNAFLDLKNSLNEVKNLLSDKKLDEWHEHTAFTNKAGKIISHVRKSVNAELCTQAWCKFHEILCSFPLIPQEAFQNGKLNSLHLCEAPGAFIASLNHYLKSHRFPCHWSWVANTLNPYHEANDDLMMIMDDRLIANTLHWWYFGPDNTGDIMTLKFLTGLQNFISSMATVHLVTADGSFDCQGNPGEQEALVSSLHYCEVVTALTTLGNGGSFVLKMFTMFEHCSINLMYLLNCCFDQVHVFKPATSKAGNSEVYVVCLHYKGREAIHPLLSKMTLNFGTEMKRKALFPHHVIPDSFLKRHEECCVFFHKYQLETISENIRLFECMGKAEQEKLNNLRDCAIQYFMQKFQLKHLSRNNWLVKKSSIGCSTNTKWFGQRNKYFKTYNERKMLEALSWKDKVAKGYFNSWAEEHGVYHPGQSSILEGTASNLECHLWHILEGKKLPKVKCSPFCNGEILKTLNEAIEKSLGGAFNLDSKFRPKQQYSCSCHVFSEELIFSELCSLTECLQDEQVVVPSNQIKCLLVGFSTLRNIKMHIPLEVRLLESAELTTFSCSLLHDGDPTYQRLFLDCLLHSLRELHTGDVMILPVLSCFTRFMAGLIFVLHSCFRFITFVCPTSSDPLRTCAVLLCVGYQDLPNPVFRYLQSVNELLSTLLNSDSPQQVLQFVPMEVLLKGALLDFLWDLNAAIAKRHLHFIIQREREEIINSLQLQN", "length": 770 }, "evidence": [ { "id": "G3MZP6", "url": "https://omabrowser.org/oma/group/G3MZP6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "methyltransferase cap1 activity", "id": "GO:0004483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004483", "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ], "pmid": "" }, { "name": "methyltransferase cap2 activity", "id": "GO:0120550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120550", "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ], "pmid": "" }, { "name": "7-methylguanosine mRNA capping", "id": "GO:0006370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006370", "evidence": [ { "database": "UniProtKB", "id": "G3MZP6", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "67024", "name": "", "equation": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MZP6-1" ], "evidence": [ { "id": "67024", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67024" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "G3MZP6", "gene_name": "CMTR2", "activity": [ { "ec_number": "2.1.1.296", "activity": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ] }, { "ec_number": "2.1.1.296", "activity": "", "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP6" }, { "id": "PS51614", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51614" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Adrift-type SAM-dependent 2'-O-MTase", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 320, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.296", "ec_name": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.296", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.296" }, { "id": "2.1.1.296", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.296" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 518, "end_pos": 520 } ] }, "class_list": [], 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"MRAVVVAANVILLLSMGGTSNSLCSPTVFYRDCWIRRFPGFLIDLEESQKLGAQFLRYSSENTGQKCSRNCCLRKDVSCNLAVFFHDPIHDNVNCLHVHCPTLESCILEPGTSAILYNITDGIDPDLLVFEQSLPTYLNTRSSSDTWERLRILKAMYLDKQQTTMINQMLPSIEAPSPTTHQELATTNNTRYSKELTTDSWARFIALNDSITTKINTVSASTDFINNPDNKTVSPFFVPRDTKLSHMPSPSQLNSSKQLLNKTKGSNSRNHTSKNEDSTPGGAPVTGVKTWLVPVALCTAVIFLCSCVVILASGCCRKQYGQYKPGQRKSGPR", "length": 333, "header": "tr|G3MZR6-1|G3MZR6_BOVIN Isoform 1 of MANSC domain containing 4 OS=Bos taurus OX=9913 GN=MANSC4 PE=4 SV=2 CANONICAL=G3MZR6-1" }, "isoforms": [ { "isoform_ac": "G3MZR6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZR6/entry", "sequence": { "sequence": "MRAVVVAANVILLLSMGGTSNSLCSPTVFYRDCWIRRFPGFLIDLEESQKLGAQFLRYSSENTGQKCSRNCCLRKDVSCNLAVFFHDPIHDNVNCLHVHCPTLESCILEPGTSAILYNITDGIDPDLLVFEQSLPTYLNTRSSSDTWERLRILKAMYLDKQQTTMINQMLPSIEAPSPTTHQELATTNNTRYSKELTTDSWARFIALNDSITTKINTVSASTDFINNPDNKTVSPFFVPRDTKLSHMPSPSQLNSSKQLLNKTKGSNSRNHTSKNEDSTPGGAPVTGVKTWLVPVALCTAVIFLCSCVVILASGCCRKQYGQYKPGQRKSGPR", "length": 333, "header": "tr|G3MZR6-1|G3MZR6_BOVIN Isoform 1 of MANSC domain containing 4 OS=Bos taurus OX=9913 GN=MANSC4 PE=4 SV=2 CANONICAL=G3MZR6-1" }, "locus": { "chromosome": "5", "start_pos": 82077396, "end_pos": 82070566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064430.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064430.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055069.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055069.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "", "database": "GlyGen", "url": 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"https://omabrowser.org/oma/group/G3MZR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4ADQ5-1", "protein_name": "MANSC domain containing 4", "gene_name": "Mansc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAAGLLLLLLLGLASTVHGLCSPTVFYRDCWIRRFPGLLLDLEESQRLGAQFLKYYSENTGQKCGRSCCLRKDVSCNVAVFFHDPIHDNVNCLHVHCPTLESCILEPGTGAILYNITAGIDPDLLVFEHSPPTYPNTRSSSEWWDRLRILKAMNAGDEGIYPDVMNHTVPSTEAASTTHHDLGANTGISYSRKSTADVGMRFTSSRVPTATNVSTGSPSTDFTPSPDNKTISPFFGPTDTDVSQVPSQSRLNISKPSVNKTKGSHSGNHTSDSKEPRDGTPASAGAWLACVTLGAAMVSLCCRVVLGTSRYCGKQQGWSHVGQGTGSGCKRSTLKETS", "length": 339 }, "evidence": [ { "id": "G3MZR6", "url": "https://omabrowser.org/oma/group/G3MZR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SG96-1", "protein_name": "MANSC domain containing 4", "gene_name": "MANSC4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCVAVLATDVFLLLSMGWTTDSLCSPTMFYRDCWIRRFPGLLIDLEESQKLGAQFLKYYSESTGRRCSQSCCLRKDVSCNLAVFFHDPVHDNVNCLHVHCPTLESCILEPGTNAILYNITDGIDPDLLVFEQSLPTYLNTRSSSNTRERLRILKAMNLDKQQPTMINQMLRSIEAPSSTAHQDFVATTNTRYSKELTTDSWARFIFLNDSISTKVNMVSPSTDFINNPDNKTLSPFFVPVDTKLSHMPIPSQLNSSKQLLNKTKGYNSRNHTSESEDIAPDPASATSKTWLVPVALCTSVIFLCCCGVILASGCYRKQQGQYKPGQRKSGSRQMKKCTLLKERS", "length": 344 }, "evidence": [ { "id": "G3MZR6", "url": "https://omabrowser.org/oma/group/G3MZR6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UU94-1", "protein_name": "MANSC domain-containing protein 4", "gene_name": "Mansc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAVELLLLLGLASMVHGLCSPTVFYRDCWIRRFPGMLLDLEESQRLGAQFLKYYSENTGQKCGRSCCLRKDVSCNVAVFFHDPVHDNVNCLHVHCPTLESCILEPGASAILYNITAGIDPDLLVFEHTSPIYPNSRSSSEWWDRLRILKAMSVGSEGVYPDVMNRMVPSTEAASTTQQDLGANTGISYSRKSTTDVGLRFTSANVSTATKVNMVSPSTDFTHSPGNKTISPFFGPTDTRVSQVPSRSRLNISKPSVNKTKGSHSRNHSSENEEPWDGAPASAGVWLACVTLGAAVISLCCRVVLGTSRCCGKRQGWSHMGQRSASGCRRNTLKENS", "length": 337 }, "evidence": [ { "id": "G3MZR6", "url": "https://omabrowser.org/oma/group/G3MZR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "R4GIB0-1", "protein_name": "MANSC domain containing 4", "gene_name": "MANSC4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVMLVAISEVLLLLGLAVESDSLCTPTIFYKNCWIRRFPGLLIDLQESQKRGAQVLRIYAEVSSQQCSRTCCLQRNVSCNLAVFYHGATNENMNCLHVSCPALESCILKARINVVLYNITTGIDPDLLIFEKLKFKGPSIYTSPNKYVRQNSTKTSEWERCQHGNVTSSSLLLQAPSSTISNSITANTFTSSTSLTVVKTKGSTYSRESTSLLDNHLAKRTNTTSGSTRLFTSSDRRTVHSTLIPTSAEVLSRMPTPPHLNSSKQHLNETKGYGGRNYTSDNEAPAWEPAALSVWLIPVALCSYLIFLCFCTVAPGAGCCRSRKGHYQPIRRGRTMSRQIKYITVQGSL", "length": 349 }, "evidence": [ { "id": "G3MZR6", "url": "https://omabrowser.org/oma/group/G3MZR6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "G3MZR6", "url": "https://www.uniprot.org/uniprotkb/G3MZR6" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "G3MZR6", "url": "https://www.uniprot.org/uniprotkb/G3MZR6" } ], "pmid": "" }, { "name": "epidermis development", "id": "GO:0008544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008544", "evidence": [ { "database": "UniProtKB", "id": "G3MZR6", "url": "https://www.uniprot.org/uniprotkb/G3MZR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "G3MZR6", "url": "https://www.uniprot.org/uniprotkb/G3MZR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MZR6", "url": "https://www.uniprot.org/uniprotkb/G3MZR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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domain-containing protein 1 OS=Bos taurus OX=9913 GN=LRFN1 PE=3 SV=3 CANONICAL=G3MZS2-1" }, "locus": { "chromosome": "18", "start_pos": 49024281, "end_pos": 49018269, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063750.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063750.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055075.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055075.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100301431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301431", "resource": "KEGG Pathway" }, { "id": "R-BTA-8849932", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849932", "resource": "Reactome", "description": "Synaptic adhesion-like molecules" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "G3MZS2", "url": "https://www.uniprot.org/uniprotkb/G3MZS2" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": 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"categories": [ "Protein Classification" ] }, { "id": "PF05287", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05287", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N073", "url": "https://www.uniprot.org/uniprotkb/G3N073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N073-1", "url": "https://www.uniprot.org/uniprotkb/G3N073-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSRPPLKHSGSMAFLGYPGNCSGISYRTHCYFPVTASVALCSSDVSPTFGLSLPSSYHGNLWLLDNCQETCGEAPSCDSPSSEPKTCTTTCDRSNSSVPCNSPTGGQICSARETTNVGPSPSCNPCPQTKGYVSDGCTPSQCTSKACQTLGNGFKCFGQLNRLSKSFQPLSHYRLGSFGYKSYQDLGIIPSGLSPSRYITNSCQRQNYLIRNCQCPYDWHRRCPPLSYFARNFRSLSSIPSSFPPLRYLYGGYRPLNYYRSTCNCSC", "length": 268, "header": "tr|G3N073-1|G3N073_BOVIN Isoform 1 of Keratin-associated protein 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9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHAGSMSLLGCPGDCSVTSYRTYCYIPVTTSVAFYSSDVSPTFRLGLPSSYQGNLWLLDNCQETQDEAPSCESPNCEPKTCTTSCDQSNTSVPCNSPTVDKSHSACETTNIRANPSCNTCTQTQGYVSDCSIPSQGTSKACQTLSSGFKCFGQLNCLSKSFRPLNHYRLSSLGYRSHQNLGFIPSGFSPLCCIANSCQSPHYFIRHCQYPSYPYISCPPLSYFSRNLQSLSCIPSTFPPLRYLCSGCRPLNCY", "length": 253 }, "evidence": [ { "id": "G3N073", "url": "https://omabrowser.org/oma/group/G3N073/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R854-1", "protein_name": "Keratin-associated protein", "gene_name": "Krtap24-1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLRGYSRLCSATSHRNHCYIPVTPSIAVCSEDVNPTFGHYLPSSYQGNLWLLDHCQDSYCEAPCCDSPSCVLKTCPASSDPTDSCVPCKSPTANQVVSDCKTTNIRCRPSCSPCPGTKGYVSNCTTATRFASKACQTLQNGSRCIEQYNSFLGNLQAPYHCIRGNNEYRSYRNFGFITNGFSPSCYTISSYHPRSYLMRYCQYPNYGSSSFPSRSYLCRNFRSLSCIPSTFPPLRYLCSSNRPLNCY", "length": 248 }, "evidence": [ { "id": "G3N073", "url": "https://omabrowser.org/oma/group/G3N073/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3LI83-1", "protein_name": "Keratin-associated protein 24-1", "gene_name": "KRTAP24-1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAGSMSTTGYPGVCSTTSYRTHCYIPVTSSVTLSSSDLSPTFGHCLPSSYQGNLWLLDYCQESYGEAPTCKSPSCEPKTCSTTGCDPSNSSVPCNSPSAGQVFSVCETTNVSPSPSCSPSTQTNGYVCNCHIPTRNASKACQTLRNGSNCFGQLNCLSKSFQTLNHCRLSTLGYKSYQNPCFIPSYVSPLCYISNSCQPQSYLVRNYHYSSYRPTSCRPLSYLSRSFRSLSYIPSTFPPLRYLCSGSRPLKCY", "length": 254 }, "evidence": [ { "id": "G3N073", "url": "https://omabrowser.org/oma/group/G3N073/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3N073", "url": "https://www.uniprot.org/uniprotkb/G3N073" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "G3N073", "url": "https://www.uniprot.org/uniprotkb/G3N073" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "G3N073", "url": "https://www.uniprot.org/uniprotkb/G3N073" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376844" }, "gene_names": [ { "name": "OR13C2C", "type": "recommended", "evidence": [ { "id": "G3N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N079" } ] }, { "name": "OR13C2C", "type": "synonym", "evidence": [ { "id": "NP_001376844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376844" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N079/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 13C2", "type": "synonym", "evidence": [ { "id": "NP_001376844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376844" } ] }, { "name": "olfactory receptor family 13 subfamily C member 2C", "type": "synonym", "evidence": [ { "id": "NP_001376844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376844" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N079", "url": "https://www.uniprot.org/uniprotkb/G3N079#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"https://omabrowser.org/oma/group/G3N081/", "database": "OMA" }, { "id": "G3N081", "url": "https://omabrowser.org/oma/group/G3N081/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P59259-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "G3N081", "url": "https://omabrowser.org/oma/group/G3N081/", "database": "OMA" }, { "id": "G3N081", "url": "https://omabrowser.org/oma/group/G3N081/", "database": "OMA" }, { "id": "G3N081", "url": "https://omabrowser.org/oma/group/G3N081/", "database": "OMA" }, { "id": "G3N081", "url": "https://omabrowser.org/oma/group/G3N081/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P62801-1", "protein_name": 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"G3N087", "url": "https://www.uniprot.org/uniprotkb/G3N087", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N087-1", "url": "https://www.uniprot.org/uniprotkb/G3N087-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKWLVLLWLVAFSECIVKIPLRVKTMRKTLSGKNTLNNFLKEHAYSLSQISSRESNLTIHPLRNIMDMLYVGNITIGTPPQEFQVVFDTGSSDLWVPPVFCQSLACATKSMFIHLRSSTFWHTQKFFNIKYNTGRMKGLLVYDTVWIGDLVSTDQPFCISLAEVGFDGIPFDGDLGLNYPNMSFSGAIPIFDNLKNEGAISEPVFAFYLSKDKQEGSVVMFGGVDHRYYKGELNWVPLIQAGGWSVHMDRISMKRKIIACSGGCEALVDTGTALIKGPRRLVNNIQKLMGATPRGSKHYVSCSAVNTLPSIIFTINGISYPVPARAYILKDSRSHCYTTFKENTVRTSREIWILGDVFLRLYFSVFDRRNDRIGLARAV", "length": 379, "header": "tr|G3N087-1|G3N087_BOVIN Isoform 1 of Peptidase A1 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3N087-1" }, "isoforms": [ { "isoform_ac": "G3N087-1", "url": "https://www.uniprot.org/uniprotkb/G3N087/entry", "sequence": { "sequence": "MKWLVLLWLVAFSECIVKIPLRVKTMRKTLSGKNTLNNFLKEHAYSLSQISSRESNLTIHPLRNIMDMLYVGNITIGTPPQEFQVVFDTGSSDLWVPPVFCQSLACATKSMFIHLRSSTFWHTQKFFNIKYNTGRMKGLLVYDTVWIGDLVSTDQPFCISLAEVGFDGIPFDGDLGLNYPNMSFSGAIPIFDNLKNEGAISEPVFAFYLSKDKQEGSVVMFGGVDHRYYKGELNWVPLIQAGGWSVHMDRISMKRKIIACSGGCEALVDTGTALIKGPRRLVNNIQKLMGATPRGSKHYVSCSAVNTLPSIIFTINGISYPVPARAYILKDSRSHCYTTFKENTVRTSREIWILGDVFLRLYFSVFDRRNDRIGLARAV", "length": 379, "header": "tr|G3N087-1|G3N087_BOVIN Isoform 1 of Peptidase A1 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3N087-1" }, "locus": { "chromosome": "29", "start_pos": 38759895, "end_pos": 38750724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063428.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063428.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055244.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055244.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3N087", "url": "https://www.uniprot.org/uniprotkb/G3N087" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3N087", "url": "https://www.uniprot.org/uniprotkb/G3N087" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "G3N087", "url": "https://www.uniprot.org/uniprotkb/G3N087" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N087-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 379, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N087-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N087" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N087", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N087" }, { "id": "PS51767", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A1", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 376, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N091-1", "uniprot_ac": "G3N091", "uniprot_id": "G3N091_BOVIN", "mass": { "chemical_mass": 101821.0, "monoisotopic_mass": 101821.0 }, "refseq": { "ac": "XP_024836525", "name": "centrobin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836525" }, "gene_names": [ { "name": "CNTROB", "type": "recommended", "evidence": [ { "id": "G3N091", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N091" } ] }, { "name": "CNTROB", "type": "synonym", "evidence": [ { "id": "XP_024836525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836525" } ] } ], "protein_names": [ { "name": "Centrobin, centriole duplication and spindle assembly protein", "type": "synonym", "evidence": [ { "id": "G3N091", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N091/entry#names_and_taxonomy" } ] }, { "name": "centrobin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024836525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836525" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N091", "url": "https://www.uniprot.org/uniprotkb/G3N091" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CNTROB", "url": "https://www.uniprot.org/uniprotkb/G3N091", "locus": { "chromosome": "19", "start_pos": 27628114, "end_pos": 27613221, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047756", "url": "https://www.ensembl.org/id/ENSBTAG00000047756" } ] } } ], "crossref": [ { "id": "G3N091", "url": "https://alphafold.ebi.ac.uk/entry/G3N091", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047756", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047756", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539106", "url": "https://www.ncbi.nlm.nih.gov/gene/539106", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539106", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539106", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N091", "url": "https://www.orthodb.org/?gene=G3N091", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34439", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34439", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34439:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34439:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_024836525", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836525", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P1J8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1J8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N091", "url": "https://www.uniprot.org/uniprotkb/G3N091", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N091-1", "url": "https://www.uniprot.org/uniprotkb/G3N091-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASAASPTSPLRAKDLLSESSEAPGLNQVSSEVTSQLYTSLHLSRQAESTARAQLYLPAASPPPHEVLDGLAQELSHSLSVGLENNVKKKDGSKHIFEMESVRGQLQSMLQTSRDAAYRDPPIPGADSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQAFEELFPRYTSLRPGPPLNPPDFQGLRDALDSEHTRRKHCERHIQNLQTRVLELQQQLAVAVTADRKKDIMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEERQAAELTRSKQQETVTRLEQSLSEAMEALSREQEGARLQQREKETLEEERQALTLSLELEQQRCQVLQEERDEARAGQLSERRQLETLQVALEEERRSWAQQEHQLKERYQALQEESQAQLEREKGNTQREAQATREAQQQLALLQSEVQRLEGELDTARRERDALQLEMSLVQARYESQRIQMESELAVQLEQRVTERLAQAQESSLRQAASLRDHHRKQLQELNGQHQQELSTQLAQFKVEIAEREERQQQVAQDYELRLAREQARVRELQSGNQQLEEQRVELVERLQAMLQAHWEEATRLLSTTTLPPHPPVPPAGPSSPGPQEPDKGERRIWTVPTMAVALKPVLQQSRETREELPGVPPPVLCSPSPDLSLLLGPTFQSQHSFQPLEPKPDLTSSSVEAFSAVGTFHPDHRAERPFPEEDPGSEGDGFLKEGLPPPSQLQGLKHFLHQLLETAPQSHENPSVDQLPPKPGPLTAPSWEETPQVPRLPPPVHKTKVPLAMASSLFRVHELPSAPSQSGGPSGGSPERGGDGPASSRQLMEVSQLLRLYQARGWEALPAEDLLLYLKRLEHGGGGTDSRGENAPRRNTDSRLGEIPRKEVPSQALPRRLAVAPKTDKPPARKKSGHPAPGGVRSRGGIWR", "length": 908, "header": "tr|G3N091-1|G3N091_BOVIN Isoform 1 of Centrobin, centriole duplication and spindle assembly protein OS=Bos taurus OX=9913 GN=CNTROB PE=4 SV=3 CANONICAL=G3N091-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P1J8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J8/entry", "sequence": { "sequence": "MAASAASPTSPLRAKDLLSESSEAPGLNQVSSEVTSQLYTSLHLSRQAESTARAQLYLPAASPPPHEVLDGLAQELSHSLSVGLENNVKKKDGSKHIFEMESVRGQLQSMLQTSRDAAYRDPPIPGADSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQAFEELFPRYTSLRPGPPLNPPDFQGLRDALDSEHTRRKHCERHIQNLQTRVLELQQQLAVAVTADRKKDIMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEERQAAELTRSKQQETVTRLEQSLSEAMEALSREQEGARLQQREKETLEEERQALTLSLELEQQRCQVLQEERDEARAGQLSERRQLETLQVALEEERRSWAQQEHQLKERYQALQEESQAQLEREKGNTQREAQATREAQQQLALLQSEVQRLEGELDTARRERDALQLEMSLVQARYESQRIQMESELAVQLEQRVTERLAQAQESSLRQAASLRDHHRKQLQELNGQHQQELSTQLAQFKVEIAEREERQQQVAQDYELRLAREQARVRELQSGNQQLEEQRVELVERLQAMLQAHWEEATRLLSTTTLPPHPPVPPAGPSSPGPQEPDKGERRIWTVPTMAVALKPVLQQSRETREELPGVPPPVLCSPSPDLSLLLGPTFQSQHSFQPLEPKPDLTSSSVEAFSAVGTFHPDHRAERPFPEEDPGSEGDGFLKEGLPPPSQLQGLKHFLHQLLETAPQSHENPSVDQLPPKPGPLTAPSWEETPQVPRLPPPVHKTKVPLAMASSLFRVHELPSAPSQSGGPSGGSPERGGDGPASSRQLMEVSQLLRLYQARGWEALPAEDLLLYLKRLEHGGGGYHPGREGRRDWVQGIWTVNGKSVECVC", "length": 870, "header": "tr|A0ABI0P1J8-1|A0ABI0P1J8_BOVIN Computationally mapped isoform of Centrobin, centriole duplication and spindle assembly protein OS=Bos taurus OX=9913 GN=CNTROB PE=4 SV=1 CANONICAL=G3N091-1" }, "locus": { "chromosome": "19", "start_pos": 27626298, "end_pos": 27613420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143653.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143653.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106863.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106863.1" } ] } }, { "isoform_ac": "G3N091-1", "url": "https://www.uniprot.org/uniprotkb/G3N091/entry", "sequence": { "sequence": "MAASAASPTSPLRAKDLLSESSEAPGLNQVSSEVTSQLYTSLHLSRQAESTARAQLYLPAASPPPHEVLDGLAQELSHSLSVGLENNVKKKDGSKHIFEMESVRGQLQSMLQTSRDAAYRDPPIPGADSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQAFEELFPRYTSLRPGPPLNPPDFQGLRDALDSEHTRRKHCERHIQNLQTRVLELQQQLAVAVTADRKKDIMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEERQAAELTRSKQQETVTRLEQSLSEAMEALSREQEGARLQQREKETLEEERQALTLSLELEQQRCQVLQEERDEARAGQLSERRQLETLQVALEEERRSWAQQEHQLKERYQALQEESQAQLEREKGNTQREAQATREAQQQLALLQSEVQRLEGELDTARRERDALQLEMSLVQARYESQRIQMESELAVQLEQRVTERLAQAQESSLRQAASLRDHHRKQLQELNGQHQQELSTQLAQFKVEIAEREERQQQVAQDYELRLAREQARVRELQSGNQQLEEQRVELVERLQAMLQAHWEEATRLLSTTTLPPHPPVPPAGPSSPGPQEPDKGERRIWTVPTMAVALKPVLQQSRETREELPGVPPPVLCSPSPDLSLLLGPTFQSQHSFQPLEPKPDLTSSSVEAFSAVGTFHPDHRAERPFPEEDPGSEGDGFLKEGLPPPSQLQGLKHFLHQLLETAPQSHENPSVDQLPPKPGPLTAPSWEETPQVPRLPPPVHKTKVPLAMASSLFRVHELPSAPSQSGGPSGGSPERGGDGPASSRQLMEVSQLLRLYQARGWEALPAEDLLLYLKRLEHGGGGTDSRGENAPRRNTDSRLGEIPRKEVPSQALPRRLAVAPKTDKPPARKKSGHPAPGGVRSRGGIWR", "length": 908, "header": "tr|G3N091-1|G3N091_BOVIN Isoform 1 of Centrobin, centriole duplication and spindle assembly protein OS=Bos taurus OX=9913 GN=CNTROB PE=4 SV=3 CANONICAL=G3N091-1" }, "locus": { "chromosome": "19", "start_pos": 27627110, "end_pos": 27613420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064781.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064781.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055248.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055248.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539106", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539106", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "G3N091", "url": "https://www.uniprot.org/uniprotkb/G3N091" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "G3N091", "url": "https://www.uniprot.org/uniprotkb/G3N091" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "G3N091", "url": "https://www.uniprot.org/uniprotkb/G3N091" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "G3N091", "url": "https://www.uniprot.org/uniprotkb/G3N091" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0D4-1", "uniprot_ac": "G3N0D4", "uniprot_id": "G3N0D4_BOVIN", "mass": { "chemical_mass": 44631.0, "monoisotopic_mass": 44631.0 }, "refseq": { "ac": "XP_059739227", "name": "terminal nucleotidyltransferase 5D isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739227" }, "gene_names": [ { "name": "TENT5D", "type": "recommended", "evidence": [ { "id": "G3N0D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0D4" } ] }, { "name": "FAM46D", "type": "synonym", "evidence": [ { "id": "XP_059739227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739227" } ] }, { "name": "TENT5D", "type": "synonym", "evidence": [ { "id": "XP_059739227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739227" } ] } ], "protein_names": [ { "name": "polynucleotide adenylyltransferase", "type": "recommended", "evidence": [ { "id": "G3N0D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0D4/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.19", "type": "synonym", "evidence": [ { "id": "G3N0D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0D4/entry#names_and_taxonomy" } ] }, { "name": "terminal nucleotidyltransferase 5D isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059739227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739227" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0D4", "url": "https://www.uniprot.org/uniprotkb/G3N0D4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TENT5D", "url": "https://www.uniprot.org/uniprotkb/G3N0D4", "locus": { "chromosome": "X", "start_pos": 72055002, "end_pos": 72342060, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045653", "url": "https://www.ensembl.org/id/ENSBTAG00000045653" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045653", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045653", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100124506", "url": "https://www.ncbi.nlm.nih.gov/gene/100124506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AMTHLQY", "url": "https://omabrowser.org/oma/group/AMTHLQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059739227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11332", "url": "https://www.rhea-db.org/rhea/11332", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N0D4", "url": "https://www.uniprot.org/uniprotkb/G3N0D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0D4-1", "url": "https://www.uniprot.org/uniprotkb/G3N0D4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEIRFSNLTWDQVITLDKVLDEVIPVHGRGNFPTLAVKPKDIIHVVKDQLIEQGIIVKDTRLNGSTASYILASHSGISYKDLDVIFGVELPSDQEFQVVKDVVLGCLFDFLPKGVKKDKITLNTMKEAYVQKMVKVCNKHDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQIVLDPMLDFYTDKNGNLTNECYPVVVAESMYGDFQEAMTHLQYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACEAEIKTLERYMCSRFFIDFPDVAEQQKKIESYLRNHFIGEEKSKYDYLMTLHGVVNQSTVCLMGLERRQTLNMIALMALKVLGEQNILPNTDNVTCFYQPAPYFVAEGGYPTYYVTSGPPPIFFQPYHPLHFHVPNGMI", "length": 390, "header": "tr|G3N0D4-1|G3N0D4_BOVIN Isoform 1 of polynucleotide adenylyltransferase OS=Bos taurus OX=9913 GN=TENT5D PE=3 SV=1 CANONICAL=G3N0D4-1" }, "isoforms": [ { "isoform_ac": "G3N0D4-1", "url": "https://www.uniprot.org/uniprotkb/G3N0D4/entry", "sequence": { "sequence": "MSEIRFSNLTWDQVITLDKVLDEVIPVHGRGNFPTLAVKPKDIIHVVKDQLIEQGIIVKDTRLNGSTASYILASHSGISYKDLDVIFGVELPSDQEFQVVKDVVLGCLFDFLPKGVKKDKITLNTMKEAYVQKMVKVCNKHDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQIVLDPMLDFYTDKNGNLTNECYPVVVAESMYGDFQEAMTHLQYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACEAEIKTLERYMCSRFFIDFPDVAEQQKKIESYLRNHFIGEEKSKYDYLMTLHGVVNQSTVCLMGLERRQTLNMIALMALKVLGEQNILPNTDNVTCFYQPAPYFVAEGGYPTYYVTSGPPPIFFQPYHPLHFHVPNGMI", "length": 390, "header": "tr|G3N0D4-1|G3N0D4_BOVIN Isoform 1 of polynucleotide adenylyltransferase OS=Bos taurus OX=9913 GN=TENT5D PE=3 SV=1 CANONICAL=G3N0D4-1" }, "locus": { "chromosome": "X", "start_pos": 72058106, "end_pos": 72056937, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087746.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087746.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091371.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091371.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QGQ8-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5d", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEIRFSNLTWDHIMTLDRVLGEVIPIHGRGNFPTLEVKPKDIVHVVKDELIKQGIIVKDTRLNGSTASYILASHNGISYKDLDIIFGVDLPSDQEFQVVKDAVLGCLLDFLPKGVKKEKITLKTMKEAYVQKMVKICNNHDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQILLDSMLDFYSVPNAKLTKESCPVVVAESMYGDFQEAMIHLKYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACQKEIKTLERYMCSRFFIDFPDVAEQQKKIESYLRNHFIGEEKSKYDYLMTLHGVVNQSTVCLMGYERRQTLNMITLLALKVLGEQNILPSTDNVTCFYQPAPYLVLEGGYPSYYVASGPPLVYFQPCPTVRLPVRNGMM", "length": 390 }, "evidence": [ { "id": "G3N0D4", "url": "https://omabrowser.org/oma/group/G3N0D4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B1ATX6-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEIRFSNLTWDHIVTLDRVLHEVIPIHGRGNFPTLEVKPKDIIHIVKDQLIKQGIVVKDTRLNGSTASYILASHNGISYKDLDIIFGVDIPSDEEFHVVKDAVLSCLFDFLPKGVKKEKITLKTMKEAYVQKMVKICNNHDRWSLISLSNNNGKNVELKFVNSLRRQFEFSVDSFQILLDSMLDFYSVPNAKLTKESCPVVVAESMYGDFQEAMIHLKYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACQTEIKTLERYMCSRFFIDFPDVAEQQKKIESYLHNHFIGEAKNKYDYLMTLHGVVNQSTVCLMGYERRQTLNMITLLALKVLGEQNILPSTDNVTCFYQPAPYLVLEGGYPSYYVASGLPLVYFQPCHTVQFPVQNGMM", "length": 390 }, "evidence": [ { "id": "G3N0D4", "url": "https://omabrowser.org/oma/group/G3N0D4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A3M4-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "Tent5d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEIRFSNLTWDHIVTLDRVLDEVIPIHGRGNFPTLEVKPKDIVHVVKDQLIKQGIIVKDTRLNGSTASYILASHNGISYKDLDIIFGVDLPSDQEFQVVKDAVLGCLLDFLPKGVKKEKITLKTMKEAYVQKMVKICSNNDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQILLDSMLDFYSVPNAKLTKESCPVVVAESMYGDFQEAMVHLKYKLISTRKPEEIRGGGLLKYSNLLVRDFKPACQTEIKTLERYMCSRFFIDFPDVAEQQKKIESYLRNHFIGEEKSKYEYLMTLHGVVNQSTVCLMGYERRQTLNMITLLALKVLGEQNILPSTDNVTCFYQPAPYLVLEGGYPSYYVASGPPLVYFQPCHTVQFPVQNGMM", "length": 390 }, "evidence": [ { "id": "G3N0D4", "url": "https://omabrowser.org/oma/group/G3N0D4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N8K6-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "FAM46D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTEDLDHRFSRLTWDQIKILDQVLAEVIPIHGRGNFPTLEVKPKDIIRVVKEQLIEKQINIRDIRLNGSTASHILVKQNGTSYKDLDIIFGVELPSELEFQVVKEAVLNCLLDFLPKCVNKEKITAQTMKDAYVQKMVKVSTDHDRWSLISLSNNSGKNVELKFVNSLRRQFEFSVDSFQIVLDSILNVYRETDCKLTEDSHPTIIAESMYGDFNEAMDHLKYKLISTRNPEEIRGGGLLKYSNLLVRDFKPADEAEIKSLERYMCSRFFIDFPDVAEQQRKIESYLRNHFIGEEKSKYDYLMTLRGVVNESTVCLMGHERRQTLNMITILALKVLGEQNIIPNAANVTCYYQPAPYISDRNFSNYYIAHGQPPIIYQPYPFHIQMQSGMV", "length": 391 }, "evidence": [ { "id": "G3N0D4", "url": "https://omabrowser.org/oma/group/G3N0D4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S1S5-1", "protein_name": "polynucleotide adenylyltransferase", "gene_name": "TENT5D", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEIRFSNLTWDQVMTLDQVLNEVIPIHGRGNFPTLEVKPKDIIHVVKDQLIEQGIIVKDTRLNGSTASYILASHNGISYKDLDVIFGVELPSDQEFQVVKDVVLGCLLDFLPKGVKKEKITLKTMKEAYVQKMVKVCNKHDRWSLISLSNNTGKNVELKFVNSLRRQFEFSVDSFQIVLDPILEFYSDKNGKLTKAFYPVVVAESMYGDFQEAMTHLQYKLISTRKPEEIRGGGLLKYSNLLVRNFKPACEAEIKTLERYMCSRFFIDFPNVEEQQKKIESYLRNHFIGEEKSKYDYLMTLRGVVNESTVCLMGHERRQTLNMITLMALKVLGEQNILPNTENVTCFYQPAPYFAAEGGYPAYYVTSGPPPIFFQPYHPLHFHVPNGMV", "length": 390 }, "evidence": [ { "id": "G3N0D4", "url": "https://omabrowser.org/oma/group/G3N0D4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8NEK8-1", "protein_name": "Terminal nucleotidyltransferase 5D", "gene_name": "TENT5D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEIRFTNLTWDQVITLDQVLDEVIPIHGKGNFPTMEVKPKDIIHVVKDQLIGQGIIVKDARLNGSVASYILASHNGISYKDLDVIFGVELPGNEEFQVVKDAVLDCLLDFLPKDVKKEKLSPDIMKDAYVQKLVKVCNGHDCWSLISLSNNTGKNLELKFVSSLRRQFEFSVDSFQIVLDPMLDFYSDKNAKLTKESYPVVVAESMYGDFQEAMTHLQHKLICTRKPEEIRGGGLLKYCSLLVHGFKPACMSEIKNLERYMCSRFFIDFPHIEEQQKKIESYLHNHFIGEGMTKYDYLMTLHGVVNESTVCLMSYERRQILHLITMMALKVLGELNILPNTQKVTCFYQPAPYFAAEARYPIYVIPEPPPVSFQPYHPLHFRGSNGMS", "length": 389 }, "evidence": [ { "id": "G3N0D4", "url": "https://omabrowser.org/oma/group/G3N0D4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "G3N0D4", "url": "https://www.uniprot.org/uniprotkb/G3N0D4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "G3N0D4", "url": "https://www.uniprot.org/uniprotkb/G3N0D4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11332", "name": "", "equation": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9RXW0-1", "G3N0D4-1", "G5E6N3-1", "P25500-1", "Q2HJ44-1", "Q1JPD6-1", "A0A3Q1MNQ1-1", "Q29RH2-1", "A0AAA9S9R3-1", "A0A3Q1MRX7-1", "A0ABI0NNI6-1" ], "evidence": [ { "id": "11332", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11332" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MNQ1", "gene_name": "TUT1", "activity": [ { "ec_number": "2.7.7.52", "activity": "RNA(n) + UTP = RNA(n)-3'-uridine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A3Q1MNQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNQ1" } ] }, { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A3Q1MNQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNQ1" } ] }, { "ec_number": "2.7.7.52", "activity": "", "evidence": [ { "id": "A0A3Q1MNQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNQ1" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "A0A3Q1MNQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNQ1" } ] } ] }, { "uniprot_ac": "A0A3Q1MRX7", "gene_name": "TENT4A", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A3Q1MRX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRX7" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "A0A3Q1MRX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRX7" } ] } ] }, { "uniprot_ac": "A0AAA9RXW0", "gene_name": "TENT5A", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0AAA9RXW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXW0" } ] }, { "ec_number": 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"id": "R-BTA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-BTA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "Q93VH9-1", "protein_name": "Small ribosomal subunit protein eS4z", "gene_name": "RPS4A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARGLKKHLKRLNAPKHWMLDKLGGAFAPKPSSGPHKSRECLPLVLIIRNRLKYALTYREVISILMQRHIQVDGKVRTDKTYPAGFMDVVSIPKTNENFRLLYDTKGRFRLHSIKDEEAKFKLCKVRSIQFGQKGIPYLNTYDGRTIRYPDPLIKPNDTIKLDLEENKIVEFIKFDVGNVVMVTGGRNRGRVGVIKNREKHKGSFETIHIQDSTGHEFATRLGNVYTIGKGTKPWVSLPKGKGIKLTIIEEARKRLSAQQA", "length": 261 }, "evidence": [ { "id": "G3N0K3", "url": 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"MATWRRDGRLTGSQRLLCAGLAGALSLSLTAPLELATVLAQVGVVRGRARGPWAAGLRVWRTEGPRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFMDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIVQNMLEPSYRGILHAFSTIYQQEGFLALYRGVSLTVLGALPFSAGSLLVYMNLEKIWNGPRDQFSLFQNFANVCLAAAVTQTLSFPFDTVKRKMQAQSPYLPHGGGVDVHFSGAMDCFRQIVKAQGVLGLWNGLAANLLKIVPYFGVMFGTFEFCKRICLYQNGYIMSPLSYKLTPGVDQSLKPQELRELNKFFKTGQLKSKKPTL", "length": 341, "header": "tr|G3N0T6-1|G3N0T6_BOVIN Isoform 1 of Solute carrier family 25 member 43 OS=Bos taurus OX=9913 GN=SLC25A43 PE=3 SV=1 CANONICAL=G3N0T6-1" }, "locus": { "chromosome": "X", "start_pos": 3840569, "end_pos": 3801253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063486.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063486.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055454.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055454.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:535541", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535541", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YK56-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "SLC25A43", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATWRRDGRLSGPQRLCCAGLAGALSLSLTAPLELLTVLAQVGTWHCGRGLLGAGRSLCRTEGVRALWKGNLTACLRLCPYSALQLAASRRLVILFTDELGHISHWRAIIAGSLAGMVATVVTYPTDLIKTRLIVQNRLEPSYEGILHAFYKIYHQEGLLALYRGVTPAILGAVPFSAGSFFVYINLDKIWQEPIVCFTPLQNFINGCVAAGVAQTLSFPFETVKRKMQAQSPWLPHCGTVDVHFTGMADCFRQTMKNKGVLGLWSGLTPSLLKIVPYFGVMFSTFEFCKRVCLYRNGYIESPLSYKLTPGVDQSLLPQELRELKHLRRENFEPRKSAVEN", "length": 341 }, "evidence": [ { "id": "G3N0T6", "url": "https://omabrowser.org/oma/group/G3N0T6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2A3V2-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "Slc25a43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATWRRDGRLTGSQRLLCAGLAGAFSLSLTAPLELATVLAQVGKVQSHSLGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMVQLAAYRKFVVLFMDDLGRISQWSSIVTGSLAGMVSTIVTYPTDLIKTRLMVQNVLEPSYRGLIHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAGSLLVYMNLEKVWNGPRDRFSHLQNFANVCVAAAVSQTLSFPFDTVKRKMQAQSPYLPHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFSMFEFCKRIFLYQNGYTLSPLTYKLTPGVDQSLKPQELRELKKFFKRRKLHSKTPPW", "length": 341 }, "evidence": [ { "id": "G3N0T6", "url": "https://omabrowser.org/oma/group/G3N0T6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZG94-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "Slc25a43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATWRRDGRLTGSQRFLCAGLAGAFSLSLTAPLELATVLAQVGRVQSHSQGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSVVQLAAYRKFVVLFMDDLGRISQWSSIVAGSLAGMVSTIVTYPTDLIKTRLIVQNMLEPSYRGLIHALSTIYQQEGFLALYRGASLTVLGAVPFSAGSLLVYMNLEKIWTGPRDRFSHLQNFATVCVAAAVSQAVSFPFDTVKRKMQAQSPYLPHYGGVDIHFSGAVDCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFGMFEFCKRIFLYQNGYTLSPLTYKLTPGVDQSLKPQELRELKKLF", "length": 329 }, "evidence": [ { "id": "G3N0T6", "url": "https://omabrowser.org/oma/group/G3N0T6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7GPX4-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "SLC25A43", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATWRRDGRLTGSQRLLCAGLAGALSLSLTAPLELATVLAQVGVVRGRARGPWAAGLRVWRAEGPRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWRSVMAGSLAGMVSTVVTYPTDLIKTRLIVQNMLEPSYRGIFHAFSTIYQQEGLLAFYRGVSLTVLGALPFSVGSLLVYMNLEKIWNGPRDRFSLLQNFANICLAAAVTQTLSFPFDTVKRKMQAQSPYLPHGGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLAANLLKIVPYFGVMFGTFEFCKRICLYQNGYIMSPLSYKLTPGVDQSLKPQELRELKKFFKTGQLKSKKPTL", "length": 341 }, "evidence": [ { "id": "G3N0T6", "url": "https://omabrowser.org/oma/group/G3N0T6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8WUT9-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "SLC25A43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGYILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKPKPKKPTL", "length": 341 }, "evidence": [ { "id": "G3N0T6", "url": "https://omabrowser.org/oma/group/G3N0T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M024-1", "protein_name": "Thylakoid ADP,ATP carrier protein, chloroplastic", "gene_name": "TAAC", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGEEKSLLQFRSFPSLKTSDFALTEEPSWRLENNVSSNRRRGNKRSGGVFTNFASLSVAIRRDRRESTFNGRNGGGGGAFASVSVVIPKEEDEFAPTSAQLLKNPIALLSIVPKDAALFFAGAFAGAAAKSVTAPLDRIKLLMQTHGVRAGQQSAKKAIGFIEAITLIGKEEGIKGYWKGNLPQVIRIVPYSAVQLFAYETYKKLFRGKDGQLSVLGRLGAGACAGMTSTLITYPLDVLRLRLAVEPGYRTMSQVALNMLREEGVASFYNGLGPSLLSIAPYIAINFCVFDLVKKSLPEKYQQKTQSSLLTAVVAAAIATGTCYPLDTIRRQMQLKGTPYKSVLDAFSGIIAREGVVGLYRGFVPNALKSMPNSSIKLTTFDIVKKLIAASEKEIQRIADDNRKKASPNTIDEQT", "length": 415 }, "evidence": [ { "id": "G3N0T6", "url": "https://omabrowser.org/oma/group/G3N0T6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "G3N0T6", "url": "https://www.uniprot.org/uniprotkb/G3N0T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, 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"https://bgee.org/?page=gene&gene_id=ENSBTAG00000045678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11655:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11655:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N0T8", "url": "https://www.uniprot.org/uniprotkb/G3N0T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0T8-1", "url": "https://www.uniprot.org/uniprotkb/G3N0T8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTILSNQTVDIPENVDINVKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFWGEKYICRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAVLIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "length": 192, "header": "tr|G3N0T8-1|G3N0T8_BOVIN Isoform 1 of Large ribosomal subunit protein uL6 OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3N0T8-1" }, "isoforms": [ { "isoform_ac": "G3N0T8-1", "url": "https://www.uniprot.org/uniprotkb/G3N0T8/entry", "sequence": { "sequence": "MKTILSNQTVDIPENVDINVKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFWGEKYICRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAVLIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "length": 192, "header": "tr|G3N0T8-1|G3N0T8_BOVIN Isoform 1 of Large ribosomal subunit protein uL6 OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3N0T8-1" }, "locus": { "chromosome": "X", "start_pos": 73082171, "end_pos": 73081596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065194.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065194.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055456.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055456.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "G3N0T8", "url": "https://www.uniprot.org/uniprotkb/G3N0T8" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "G3N0T8", "url": "https://www.uniprot.org/uniprotkb/G3N0T8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "G3N0T8", "url": "https://www.uniprot.org/uniprotkb/G3N0T8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "G3N0T8", "url": "https://www.uniprot.org/uniprotkb/G3N0T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0T8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 192, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0T8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0T8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0T8" }, { "id": "PF00347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL6 alpha-beta", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 85, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0U2-1", "uniprot_ac": "G3N0U2", "uniprot_id": "G3N0U2_BOVIN", "mass": { "chemical_mass": 148535.0, "monoisotopic_mass": 148535.0 }, "refseq": { "ac": "XP_024844287", "name": "G2/mitotic-specific cyclin-B3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844287" }, "gene_names": [ { "name": "CCNB3", "type": "recommended", "evidence": [ { "id": "G3N0U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ] }, { "name": "CCNB3", "type": "synonym", "evidence": [ { "id": "XP_024844287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844287" } ] } ], "protein_names": [ { "name": "Cyclin B3", "type": "synonym", "evidence": [ { "id": "G3N0U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0U2/entry#names_and_taxonomy" } ] }, { "name": "G2/mitotic-specific cyclin-B3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024844287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844287" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCNB3", "url": "https://www.uniprot.org/uniprotkb/G3N0U2", "locus": { "chromosome": "X", "start_pos": 88000791, "end_pos": 87951306, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046286", "url": "https://www.ensembl.org/id/ENSBTAG00000046286" } ] } } ], "crossref": [ { "id": "G3N0U2", "url": "https://alphafold.ebi.ac.uk/entry/G3N0U2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046286", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046286", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20508", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20508", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100301478", "url": "https://www.ncbi.nlm.nih.gov/gene/100301478", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100301478", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301478", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR10177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024844287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NZS1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZS1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0U2-1", "url": "https://www.uniprot.org/uniprotkb/G3N0U2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLPLPSHHSKHETRKSQSSIVPSDREPSEKKDEKYQAKISPSSPQGPLKKRSAFEDLTNAPQSQPVQPKKEANNEFVKDTSKKRNRNTSANRLPENNKMNIKRCKVELSPIVVSTTMMPNIIDNLLTLGMSTSSKTPNTEEASLFKEPFILKEEPTSEDAVLMKRSLSSKKCTDQGVVSLLQKPLSLQGKSDSDVVQPMIFGKKCKTEETAITNRTLSLKNMCPYQGKQSCSGEELALHDVSVEEDSSFMELQNVRKKPKTEEATFTNPLSSLNKKYTTQRKMSCSKNPLVLQKTTSEEKPLTKESFKRKPTAEKESFFQEPPALQEKHTSEQEISILKKSLAFQEKIDTEDKSLFKEPLAFKKQSTTEETTFTMRPLPLNKKCTTQRKRKMTYSKMTTSGENAFISQLLSFKKKPTPKEESLFQDLSVLQEKHTDDGAVTLVKKPWALQKKDDEDDFLMEPLSFRKTHTTKEATLPKKPLLLKRKCTTQEKMYHLKKPLVLQKVTSEEKSLVKEPLPFKKPPTTKESLFQEPSALQGKHTILEEASILKKPLVLQKIPTEEESLKKETLIFKKFTTGEATSTNMLLSLKNKCTTQAKSCLTKPLVLQTISEEKSLIKEPTTEVESLLKEPSALQEKHTTQGDVAPLKKPWALQERIDSKDEFLMEPLSFRKTHTTNVAVSTKESSSLMKQTCATQTLMSIWQELLGLQNMIGEGKNSFMMPVSSRKKSSTDEAVLTKTPLSPKMRQITQWNTVIEKTTSEEESLFKKLFPLKKTSTTEEELLFQGPSVLKEKHTSLQQASLSKKPLTLQENIATQEESYIKELLTTEKSLVLQKTDTKVDFSTSLALQKKSTTEEKFFFEKPLVLKEKLSPKAAASIEGQSSFKKQPTAQGEVFLLKKQSTLQENITSEEECIIKQPQALQEKSSVEKETILRESLALQENSTIEKDAVWKEPLALQKTLAHKENTFLKHCTLQIETSPDVSTTIPESGTGLSNTITMSSSIISKSSTCESNSDKPFSSSDKKSQQEVIPLGNTDIDCSDPFFSSVYAKDIFSYMKKREEKFVLNKYMTRQTDIDSDMRAILVDWLVEVQMSFEMSHETLYLAVKLVDHYLMKEICKKDKLQLLGSTAFLIAAKFEECYPPSVDDILYICNDIYKRDEMLAMEASILKILKFDINIPIAYHFLRRYARCVCASMKTLTLSRFICELTLVEYDYVQERASKLAAASFFLALCMNKLGHWAPILEYYSGYRISDLHALVRQLNILLTFHSCNRLKAVRSKYSNKVFFEVTKIPPLDMLALDRILRCC", "length": 1307, "header": "tr|G3N0U2-1|G3N0U2_BOVIN Isoform 1 of Cyclin B3 OS=Bos taurus OX=9913 GN=CCNB3 PE=3 SV=3 CANONICAL=G3N0U2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZS1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS1/entry", "sequence": { "sequence": "MPLPLPSHHSKHETRKSQSSIVPSDREPSEKKDEKYQAKISPSSPQGPLKKRSAFEDLTNAPQSQPVQPKKEANNEFVKDTSKKRNRNTSANRLPENNKMNIKRCKVELSPIVVSTTMMPNIIDNLLTLGMSTSSKTPNTEEASLFKEPFILKEEPTSEDAVLMKRSLSSKKCTDQGVVSLLQKPLSLQGKSDSDVVQPMIFGKKCKTEETAITNRTLSLKNMCPYQGKQSCSGEELALHDVSVEEDSSFMELQNVRKKPKTEEATFTNPLSSLNKKYTTQRKMSCSKNPLVLQKTTSEEKPLTKESFKRKPTAEKESFFQEPPALQEKHTSEQEISILKKSLAFQEKIDTEDKSLFKEPLAFKKQSTTEETTFTMRPLPLNKKCTTQRKRKMTYSKMTTSGENAFISQLLSFKKKPTPKEESLFQDLSVLQEKHTDDGAVTLVKKPWALQKKDDEDDFLMEPLSFRKTHTTKEATLPKKPLLLKRKCTTQEKMYHLKKPLVLQKVTSEEKSLVKEPLPFKKPPTTKESLFQEPSALQGKHTILEEASILKKPLVLQKIPTEEESLKKETLIFKKFTTGEATSTNMLLSLKNKCTTQAKSCLTKPLVLQTISEEKSLIKEPTTEVESLLKEPSALQEKHTTQGDVAPLKKPWALQERIDSKDEFLMEPLSFRKTHTTNVAVSTKESSSLMKQTCATQTLMSIWQELLGLQNMIGEGKNSFMMPVSSRKKSSTDEAVLTKTPLSPKMRQITQWNTVIEKTTSEEESLFKKLFPLKKTSTTEEELLFQGPSVLKEKHTSLQQASLSKKPLTLQENIATQEESYIKELLTTEKSLVLQKTDTKVDFSTSLALQKKSTTEEKFFFEKPLVLKEKLSPKAAASIEGQSSFKKQPTAQGEVFLLKKQSTLQENITSEEECIIKQPQALQEKSSVEKETILRESLALQENSTIEKDAVWKEPLALQKTLAHKENTFLKHCTLQIETSPDVSTTIPESGTGLSNTITMSSSIISKSSTCESNSDKPFSSSDKKSQQEVIPLGNTDIDCSDPFFSSVYAKDIFSYMKKREMSFEMSHETLYLAVKLVDHYLMKEICKKDKLQLLGSTAFLIAAKFEECYPPSVDDILYICNDIYKRDEMLAMEASILKILKFDINIPIAYHFLRRYARCVCASMKTLTLSRFICELTLVEYDYVQERASKLAAASFFLALCMNKLGHWAPILEYYSGYRISDLHALVRQLNILLTFHSCNRLKAVRSKYSNKVFFEVTKIPPLDMLALDRILRCC", "length": 1276, "header": "tr|A0ABI0NZS1-1|A0ABI0NZS1_BOVIN Computationally mapped isoform of Cyclin B3 OS=Bos taurus OX=9913 GN=CCNB3 PE=3 SV=1 CANONICAL=G3N0U2-1" }, "locus": { "chromosome": "X", "start_pos": 88000551, "end_pos": 87955803, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150379.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150379.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106064.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106064.1" } ] } }, { "isoform_ac": "G3N0U2-1", "url": "https://www.uniprot.org/uniprotkb/G3N0U2/entry", "sequence": { "sequence": "MPLPLPSHHSKHETRKSQSSIVPSDREPSEKKDEKYQAKISPSSPQGPLKKRSAFEDLTNAPQSQPVQPKKEANNEFVKDTSKKRNRNTSANRLPENNKMNIKRCKVELSPIVVSTTMMPNIIDNLLTLGMSTSSKTPNTEEASLFKEPFILKEEPTSEDAVLMKRSLSSKKCTDQGVVSLLQKPLSLQGKSDSDVVQPMIFGKKCKTEETAITNRTLSLKNMCPYQGKQSCSGEELALHDVSVEEDSSFMELQNVRKKPKTEEATFTNPLSSLNKKYTTQRKMSCSKNPLVLQKTTSEEKPLTKESFKRKPTAEKESFFQEPPALQEKHTSEQEISILKKSLAFQEKIDTEDKSLFKEPLAFKKQSTTEETTFTMRPLPLNKKCTTQRKRKMTYSKMTTSGENAFISQLLSFKKKPTPKEESLFQDLSVLQEKHTDDGAVTLVKKPWALQKKDDEDDFLMEPLSFRKTHTTKEATLPKKPLLLKRKCTTQEKMYHLKKPLVLQKVTSEEKSLVKEPLPFKKPPTTKESLFQEPSALQGKHTILEEASILKKPLVLQKIPTEEESLKKETLIFKKFTTGEATSTNMLLSLKNKCTTQAKSCLTKPLVLQTISEEKSLIKEPTTEVESLLKEPSALQEKHTTQGDVAPLKKPWALQERIDSKDEFLMEPLSFRKTHTTNVAVSTKESSSLMKQTCATQTLMSIWQELLGLQNMIGEGKNSFMMPVSSRKKSSTDEAVLTKTPLSPKMRQITQWNTVIEKTTSEEESLFKKLFPLKKTSTTEEELLFQGPSVLKEKHTSLQQASLSKKPLTLQENIATQEESYIKELLTTEKSLVLQKTDTKVDFSTSLALQKKSTTEEKFFFEKPLVLKEKLSPKAAASIEGQSSFKKQPTAQGEVFLLKKQSTLQENITSEEECIIKQPQALQEKSSVEKETILRESLALQENSTIEKDAVWKEPLALQKTLAHKENTFLKHCTLQIETSPDVSTTIPESGTGLSNTITMSSSIISKSSTCESNSDKPFSSSDKKSQQEVIPLGNTDIDCSDPFFSSVYAKDIFSYMKKREEKFVLNKYMTRQTDIDSDMRAILVDWLVEVQMSFEMSHETLYLAVKLVDHYLMKEICKKDKLQLLGSTAFLIAAKFEECYPPSVDDILYICNDIYKRDEMLAMEASILKILKFDINIPIAYHFLRRYARCVCASMKTLTLSRFICELTLVEYDYVQERASKLAAASFFLALCMNKLGHWAPILEYYSGYRISDLHALVRQLNILLTFHSCNRLKAVRSKYSNKVFFEVTKIPPLDMLALDRILRCC", 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"G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "G3N0U2", "url": "https://www.uniprot.org/uniprotkb/G3N0U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" }, { "start_pos": 907, "end_pos": 909, "annotation": "n_glycosylation_sequon" }, { "start_pos": 943, "end_pos": 945, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0U2-F1", 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"LKRGGSQDLVSSPKLDRFKIAKQLTDKAIKEKKIFSICGHYPVIRSTLRRKGWVEKKFHFLTSLVPSVDGDGEGVPENKHAEGKENQDVALEKADDIHDVMSRLVKNETPYFLWTIKRDVIDYHSLSCDQMLNHYGKTASFTTKIGLCVSMRSLPWYVQANPDTFFPRCYSLCTESEKQEFLDDFRQTVASSILKWVVSQQSSRSKPRSRREEARDSGASRKVPEGAGPRLMGLSGQFVDVACKVCKAYLGRLEHEDIDLTEDSATDLTEDEWNDLTQQYYSLVHGEAFIPSSRNHFSQCQALLNKITSVNPQTEIDGLRNIWIIKPAAKSRGRDIVCMNHVEEILELVAADQPPAKDKWVVQKYIETPLLIYDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKLDSAIHLCNNSIQKHLKNDKDRSPLLPCHNMWTSTRFQEYLQKRGRGAVWSSVIYPSMKRAITNTMKVAQDHVEPRKNSFELYGADFILGRDFRPWLIEINSSPTMHASTPVTAQLCAQVQEDTIKVVVDRKADRNCDIGNFELLWKQPAVGLPTSQGSDLLVEGVGMRKARKPMPAIPSVDVVPPLSDIHPLKQRCPSAMLDLGGGPPLMALHQDFTLKDGQVLPCSLPVHLHRLVERSAKAKSGHRESGGKIELPSCTSQHPDYKAPRPTLAKAESDRHSDPNSLHVHPLPSVLPSVKTVEGAPFQPPRPPDTHRPSRSPVLKSGSWSDRLEDHRSFLLVCRGDKHLLLDSPPF", "length": 768, "header": "tr|G3N0U5-1|G3N0U5_BOVIN Isoform 1 of Tubulin tyrosine ligase like 8 OS=Bos taurus OX=9913 GN=TTLL8 PE=4 SV=3 CANONICAL=G3N0U5-1" }, "isoforms": [ { "isoform_ac": "G3N0U5-1", "url": 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Acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abscission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis. 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"GEGNVKASTMSHFCFLCQRCSQALKLNHSVEPSQEPGASMLISAQGETRETPEGGPPSKEEANFENLQDGAFCRTPHPPSGGMSWDYSSFTLLGRLEPWRSLNSIQKTIRDSSDILSGETEVDHPLCVDCTDYLLEVLDVELAITESDVQNYKRCLETRKWLSGDDREMLQEKLKGLELEEARLLQEVAEVEKNQERVAADLEAAQAETKMLEQQEKQYWEDYSQLKWQQLELNEELSSVEMRLQYAQLQCNQLEKTDVFNATFEIWQDGPLPVINNFRLGRLPTVPVCWDEISAAWGQTALLLLALANTVGLEFQRYHLIPCGSHSYLRSLIDDCAELPLFSSGKQNVFLHNKFDQAMMAFLDCMQQFKEAAESGESGLCLPYKIHVKKGLMEDPGSSSGFYSIRTHLNTEEDWTKALKLMLINFKCSLTWVSLRYGRK", "length": 440, "header": "tr|G3N106-1|G3N106_BOVIN Isoform 1 of Beclin 2 OS=Bos taurus OX=9913 GN=BECN2 PE=3 SV=4 CANONICAL=G3N106-1" }, "locus": { "chromosome": "16", "start_pos": 34910952, "end_pos": 34908879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018200.8", "url": "https://www.ensembl.org/id/ENSBTAT00000018200.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055528.4", "url": "https://www.ensembl.org/id/ENSBTAP00000055528.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": 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{ "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "G3N106", "url": "https://www.uniprot.org/uniprotkb/G3N106" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "G3N106", "url": "https://www.uniprot.org/uniprotkb/G3N106" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class III, type I", "id": "GO:0034271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034271", "evidence": [ { "database": "UniProtKB", "id": "G3N106", "url": "https://www.uniprot.org/uniprotkb/G3N106" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class III, type II", "id": "GO:0034272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034272", "evidence": [ { 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N116-1", "uniprot_ac": "G3N116", "uniprot_id": "G3N116_BOVIN", "mass": { "chemical_mass": 39332.0, "monoisotopic_mass": 39332.0 }, "refseq": { "ac": "XP_003586565", "name": "GRAM domain-containing protein 2A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586565" }, "gene_names": [ { "name": "GRAMD2A", "type": "recommended", "evidence": [ { "id": "G3N116", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N116" } ] }, { "name": "GRAMD2A", "type": "synonym", "evidence": [ { "id": "XP_003586565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586565" } ] } ], "protein_names": [ { "name": "GRAM domain containing 2A", "type": "synonym", "evidence": [ { "id": "G3N116", "database": "UniProtKB", "url": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "HIXYKEP", "url": "https://omabrowser.org/oma/group/HIXYKEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N121", "url": "https://www.orthodb.org/?gene=G3N121", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12756", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12756", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12756:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12756:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001341651", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001341651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "60004", "url": "https://www.rhea-db.org/rhea/60004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N121-1", "url": "https://www.uniprot.org/uniprotkb/G3N121-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEDSEKEDYSDRTISDEDESDEDNFMKFVNEDIHQCALLTADSISDPFFPRTTQILLEYQLGRWVPRLRKPRDLYGVSSSGPLSPTRWPYHCEVIDEKIEHIDWTPSNPEPMYIPTGLEVEPLYANSKEETVVYLAEDAYKEPCFVYSRVGGNRTPLKQPVDNCDDTLMFEARFESGNLQKVVKVGEYEYQLTVRPDLFTNKHTQWYYFQVTNTQAGIVYRFTITNFTKPASLYNRGMRPLFYSEKEASAHNIGWQRIGDQIKYYRNNQGQDRHHHFSLTWTFQFPHSKDTCYFAHCYPYTYTNLQEYLSGINNDPVRSKFCKIRVLCHTIARNMVYILTITTPLKNSESRKRKAVILTARVHPGETNSSWIMKGFLDYILGNSSDAKLLRDTFVFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLLKESFPSVWYTRNMIRRLMEKREVILYCDLHGHSKKENIFMYGCDGSDRCKALYLQQRIFPLMLSKNCPDKFSFSSCKFNIQKSKEGTGRVVMWKMGIRNSFTMEATFCGSTLGNKRGTHFNTKDLESMGYHFCDSLLDYCDPDRTKYYQCLKELDEMEKHINLEKVIDDSDTSLKEITLDLETSSHASDSSESNDSQTDLLKLNSQIKTKKKQLKTKKERNSTIERHQNIREEEQEVCDKGHLVQRHKESDSDVTDTRPSISDDCIFDYFRRQLPNQDLHHNLKSNMKECPSFQSKKADINWTDDEKRIYRDKNIAQTQEILQYLLPIMRSTKNVQTTQIKEVFNPRTSFQIQHQQKPSSNINIRKCSTSWTPPRNLPLISQRTLIVSTSKWLQPLDWKSSESSLPLGGPKKRRKYSRVKATKTKDMKAASSKWEMTPSSSEKDADKSLQAEGSSQQGTMQTAPHPTKTKGEQPKKKHGQPAFHLKLQRDT", "length": 921, "header": "tr|G3N121-1|G3N121_BOVIN Isoform 1 of AGBL carboxypeptidase 3 OS=Bos taurus OX=9913 GN=AGBL3 PE=3 SV=2 CANONICAL=G3N121-1" }, "isoforms": [ { "isoform_ac": "G3N121-1", "url": "https://www.uniprot.org/uniprotkb/G3N121/entry", "sequence": { "sequence": "MSEDSEKEDYSDRTISDEDESDEDNFMKFVNEDIHQCALLTADSISDPFFPRTTQILLEYQLGRWVPRLRKPRDLYGVSSSGPLSPTRWPYHCEVIDEKIEHIDWTPSNPEPMYIPTGLEVEPLYANSKEETVVYLAEDAYKEPCFVYSRVGGNRTPLKQPVDNCDDTLMFEARFESGNLQKVVKVGEYEYQLTVRPDLFTNKHTQWYYFQVTNTQAGIVYRFTITNFTKPASLYNRGMRPLFYSEKEASAHNIGWQRIGDQIKYYRNNQGQDRHHHFSLTWTFQFPHSKDTCYFAHCYPYTYTNLQEYLSGINNDPVRSKFCKIRVLCHTIARNMVYILTITTPLKNSESRKRKAVILTARVHPGETNSSWIMKGFLDYILGNSSDAKLLRDTFVFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLLKESFPSVWYTRNMIRRLMEKREVILYCDLHGHSKKENIFMYGCDGSDRCKALYLQQRIFPLMLSKNCPDKFSFSSCKFNIQKSKEGTGRVVMWKMGIRNSFTMEATFCGSTLGNKRGTHFNTKDLESMGYHFCDSLLDYCDPDRTKYYQCLKELDEMEKHINLEKVIDDSDTSLKEITLDLETSSHASDSSESNDSQTDLLKLNSQIKTKKKQLKTKKERNSTIERHQNIREEEQEVCDKGHLVQRHKESDSDVTDTRPSISDDCIFDYFRRQLPNQDLHHNLKSNMKECPSFQSKKADINWTDDEKRIYRDKNIAQTQEILQYLLPIMRSTKNVQTTQIKEVFNPRTSFQIQHQQKPSSNINIRKCSTSWTPPRNLPLISQRTLIVSTSKWLQPLDWKSSESSLPLGGPKKRRKYSRVKATKTKDMKAASSKWEMTPSSSEKDADKSLQAEGSSQQGTMQTAPHPTKTKGEQPKKKHGQPAFHLKLQRDT", "length": 921, "header": "tr|G3N121-1|G3N121_BOVIN Isoform 1 of AGBL carboxypeptidase 3 OS=Bos taurus OX=9913 GN=AGBL3 PE=3 SV=2 CANONICAL=G3N121-1" }, "locus": { "chromosome": "4", "start_pos": 98789406, "end_pos": 98691288, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065165.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065165.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055543.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055543.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:527479", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527479", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8CDP0-1", "protein_name": "Cytosolic carboxypeptidase 3", "gene_name": "Agbl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEDSEEEDYSDRSISDDDDLDEDSFMKFVSDDIHPCTLLAADSIGDPFFPRTTQILLEYQLGRWVPRLRGPRDLYGVSSSGPLSPTRWPYHCEVIDEKVQHIEWTPFVPEPVYVPTGLEIEPVYPNSKEDTVVYLAEDDHLCKAYKEPCFVYSRVGGNRTSLKQPVDNCDNTLVFEARFESGNLQKVVKVADHEYELTVRPDLFTNKHTQWYYFQVTNTQAEIVYRFTIVNFTKPASLYNRGMKPLFYSEKEAKTHNIGWQRIGDQIKYYKNNLGQDGRHFFSLTWTFQFPHSQDTCYFAHCYPYTYSNLQEYLSGINSDPVRSKFCKIRVLCHTLARNMVYVLTITTPLKTSDSKRKAVILTARVHPGETNSSWIMKGFLDYILGDSSDARLLRDTFIFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLLKESFPSVWYTRNMINRLMEKREVILYCDLHGHSRKQNIFMYGCDGSSRSKTKGLYLQQRIFPLMLSKNCPNIFSFSACKFNVQKSKEGTGRVVMWKMGIRNSFTLEATFCGSTLGNKRGTHFGTKDLESMGYHFCDSLLDYCDPDRSKYYQCLKELEEMEKHLSSERVSDNTDTSLVEISLDVESSSRGSDSSESNDTQTYLLKVTSQARNKKKYLKTKRERNAILANCQNNMQEVYGKEHLLQRHDESNSDGNDPRIDAPDVYVAHCFRRPLPNQGVVKIPGQRFYPGKTWSSSQRMIKSLNKDHRTCILETCKNPIQEVQSRGINIHESCFKMAKCPMNKRPSHWIEKTRIPTESHHQLKSKAKRCSSFQSKRTGTNWTDDEKRIYRDKRIAQTQEILKYLLPIVESSQNRKSTQMNNLINPIANLQQHQLIPTACINRRRYSIPWTPTRNLPFKAQRNLMTDTSEWLQSVPLGSFESLLPLCNLQKKTKHFELWGKKAKDVQLATSQWEAVPLSSNMDASIIRGNSVLQPKEFTMRSSKQRIPYLTKTSKKPSESDGLLTFQLKIHRNS", "length": 1006 }, "evidence": [ { "id": "G3N121", "url": "https://omabrowser.org/oma/group/G3N121/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NEM8-1", "protein_name": "Cytosolic carboxypeptidase 3", "gene_name": "AGBL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEDSEKEDYSDRTISDEDESDEDMFMKFVSEDLHRCALLTADSFGDPFFPRTTQILLEYQLGRWVPRLREPRDLYGVSSSGPLSPTRWPYHCEVIDEKVQHIDWTPSCPEPVYIPTGLETEPLYPDSKEATVVYLAEDAYKEPCFVYSRVGGNRTPLKQPVDYRDNTLMFEARFESGNLQKVVKVAEYEYQLTVRPDLFTNKHTQWYYFQVTNMRAGIVYRFTIVNFTKPASLYSRGMRPLFYSEKEAKAHHIGWQRIGDQIKYYRNNPGQDGRHYFSLTWTFQFPHNKDTCYFAHCYPYTYTNLQEYLSGINNDPVRSKFCKIRVLCHTLARNMVYILTITTPLKNSDSRKRKAVILTARVHPGETNSSWIMKGFLDYILGNSSDAQLLRDTFVFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLLKESFPSVWYTRNMVHRLMEKREVILYCDLHGHSRKENIFMYGCDGSDRSKTLYLQQRIFPLMLSKNCPDKFSFSACKFNVQKSKEGTGRVVMWKMGIRNSFTMEATFCGSTLGNKRGTHFSTKDLESMGYHFCDSLLDYCDPDRTKYYRCLKELEEMERHITLEKVFEDSDTPVIDITLDVESSSRGSDSSESIDSLTYLLKLTSQKKHLKTKKERNSTIASHQNARGQEVYDRGHLLQRHTQSNSDVKDTRPNEPDDYMVDYFRRQLPNQGLAHCKLRLPGSRHSPASASRVAGTTGTRHHTWLIFVFLVEMGKKIPLKGTDLYGNCFKVTSLQSPMGKQTSTWTEKTRIPTEDLHHNLKSKIKECISFQSKKTGINWTDDEKRSYKDKGIVQTQEILQYLLPIVHSTKNMQTTQIKQLFNPRTNFQIQHQLNPATCRNIKKYSTSWTAPRNHPFVIQGDVMANSSEWVQSKPHRSLESLSPLKGPKKNKHSQIWAIKNEDIKPLSSKWETASSSFGMDANVLKYKSLQAEETNQQSSKHTALHLTKNKDEQANKNDGQPTLYLKFQRES", "length": 1001 }, "evidence": [ { "id": "G3N121", "url": "https://omabrowser.org/oma/group/G3N121/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "G3N121", "url": "https://www.uniprot.org/uniprotkb/G3N121" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60004", "name": "", "equation": "(L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + H2O = (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + L-glutamate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9THU1-1", "Q58CX9-1", "E1B9D8-1", "A0A3Q1NNI7-1" ], "evidence": [ { "id": "60004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1NNI7", "gene_name": "AGBL1", "activity": [ { "ec_number": "3.4.17.24", "activity": "C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + L-glutamate.", "evidence": [ { "id": "A0A3Q1NNI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNI7" } ] }, { "ec_number": "3.4.17.24", "activity": "", "evidence": [ { "id": "A0A3Q1NNI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNI7" } ] } ] }, { "uniprot_ac": "A0AAA9THU1", "gene_name": "AGTPBP1", "activity": [ { "ec_number": "3.4.17.24", "activity": "C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + L-glutamate.", "evidence": [ { "id": "A0AAA9THU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THU1" } ] }, { "ec_number": "3.4.17.24", "activity": "", "evidence": [ { "id": "A0AAA9THU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THU1" } ] } ] }, { "uniprot_ac": "E1B9D8", "gene_name": "AGBL3", "activity": [ { "ec_number": "3.4.17.-", "activity": "", "evidence": [ { "id": "E1B9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D8" } ] } ] }, { "uniprot_ac": "Q58CX9", "gene_name": "AGBL5", "activity": [ { "ec_number": "3.4.17.-", "activity": "", "evidence": [ { "id": "Q58CX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CX9" } ] }, { "ec_number": "3.4.17.24", "activity": "C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + L-glutamate.", "evidence": [ { "id": "Q58CX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CX9" } ] }, { "ec_number": "3.4.17.24", "activity": "", "evidence": [ { "id": "Q58CX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58CX9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N121-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 921, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N121-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N121" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N121", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N121" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 299, "end_pos": 570, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 651, "end_pos": 653 }, { "start_pos": 731, "end_pos": 733 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 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"categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-351906", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-351906", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N156-1", "url": "https://www.uniprot.org/uniprotkb/G3N156-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADSYNNYGTSSRSSFYSKFQAGSGSWGYPIYNGTLKREADNRRFSSYSQMESWGRQYPRGGCTAPGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGGKGHKTTQNRYSFYSTCSGQKAVKKYPGRPPSCTSRQDPVCVPPTSCTKDLSFSHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKCQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGSTEIQKQLTGLLWNLSSTDELKEELIAEALPVLADRVIIPFSGWCDGNSNLSREPVDPEVFFNATGCLRNLSSADVGRQTMRNYTGLIDSLMAYVQNCVAANRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTDKSSTGCFSNKSDRMTNNNYDCPLPEEEPNPKGSSWLYHSDAVRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPHIARLLQSGNSDVVRSGASLLSNMSRHPALHRVMGTQVFPEVTRLLTSHTGNTSNSEDILASACYTVRNLMASLPGMAKQHFSSSMVNNIINLCRSSTSPKAAEAARLLLSDMWSSRELQGLLRQQGFDRSMLGTLAGANSLRNFTSRF", "length": 727, "header": "tr|G3N156-1|G3N156_BOVIN Isoform 1 of Plakophilin-1 OS=Bos taurus OX=9913 GN=PKP1 PE=3 SV=2 CANONICAL=G3N156-1" }, "isoforms": [ { "isoform_ac": "G3N156-1", "url": "https://www.uniprot.org/uniprotkb/G3N156/entry", "sequence": { "sequence": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADSYNNYGTSSRSSFYSKFQAGSGSWGYPIYNGTLKREADNRRFSSYSQMESWGRQYPRGGCTAPGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGGKGHKTTQNRYSFYSTCSGQKAVKKYPGRPPSCTSRQDPVCVPPTSCTKDLSFSHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKCQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGSTEIQKQLTGLLWNLSSTDELKEELIAEALPVLADRVIIPFSGWCDGNSNLSREPVDPEVFFNATGCLRNLSSADVGRQTMRNYTGLIDSLMAYVQNCVAANRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTDKSSTGCFSNKSDRMTNNNYDCPLPEEEPNPKGSSWLYHSDAVRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPHIARLLQSGNSDVVRSGASLLSNMSRHPALHRVMGTQVFPEVTRLLTSHTGNTSNSEDILASACYTVRNLMASLPGMAKQHFSSSMVNNIINLCRSSTSPKAAEAARLLLSDMWSSRELQGLLRQQGFDRSMLGTLAGANSLRNFTSRF", "length": 727, "header": "tr|G3N156-1|G3N156_BOVIN Isoform 1 of Plakophilin-1 OS=Bos taurus OX=9913 GN=PKP1 PE=3 SV=2 CANONICAL=G3N156-1" }, "locus": { "chromosome": "16", "start_pos": 79823331, "end_pos": 79787372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063780.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063780.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055583.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055583.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-351906", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-351906", "resource": "Reactome", "description": "Apoptotic cleavage of cell adhesion proteins" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-BTA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A511-1", "protein_name": "Plakophilin-1", "gene_name": "PKP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLHSPLKTALAYECFQDQASSTLALPSDHKLKTKGTGKQRVQEQVMMTVKRQKQKSSVSSSVGHSNRGSMYDCVADGYGYGTSRGSYYTKTQMGNSSWGYPLYNGTLKRDAENRRYSSYSQMEGWGSKHYSKAVCSPNRAGSDYCFVQNIKSSRSEPDLYCEPPRGTLRKSQVGGRAEHKATLNRQSIYSSCSTQQGTTRTSKKIPARALSCPSSNKPDVVYAQPVMSCKQDAVYGQAQSGSKICGDEIDGGTMTIQKAIQLLCSSDDKYQAMGAYYLQHTCFQDESAKQEVYRLGGIAKLVELLRSTNQNVQRAAAGALRNLVFRNPTNKIETRRQNGIRECVSLLRRTGNTEIQKQLTGLLWNLSSTDELKEELIQEALPVLTDCVIIPFSGWSDGGCNRTREIIDPEVFFNATGCLRNLSSADMGRQTMRNYPGLIDSVMTYAQNCVASNRPDDKSVENCICILHNLSYRLDAEVPNKYTQLNHMARSVYMDKTLTGCFNSRSGKMENDEYGVPLPEEDFKPKGPSWLYHSDAIRTYLSLMDHSKKDATLEACAGALQNLTASRGLMSNAMSQLIGVKEKGLPRIARLLQSNSSEVVRSGASLLSNMSRHPILHKTMAHQVLPDVSRLLSFQSGNTNSYGEIMTSACYTLRNLIMSNPHLGKCYLTSNMLNNVVSLCRNGSCPKAAEAARLLLTDLWSNRELQSVLKQQGFDKNMMGSLAGTTFRTLPSRF", "length": 734 }, "evidence": [ { "id": "G3N156", "url": "https://omabrowser.org/oma/group/G3N156/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZY51-1", "protein_name": "Plakophilin-1", "gene_name": "Pkp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLVDNYNNYGTTSRSSYFSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCATTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGGKGQKTTQNRYSFYSTCSGQKAVKKCPVRPPSCTSKQDPVCMPPISCNKDMSFGHSRASSKICSEDIECSGLTIPKAVQYLCSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRSGSTEIQKQLTGLLWNLSSTDELKEELVADALPVLTDRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCILHNLSYRLDAEVPTRYRQLEYNTRNAYTEKSSTGCFSNRGDKMMNNNYDCPLPEEETNPKGSSWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSNGMSQLIGIKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPVLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMTSQPQMAKQYFSNSMLNNVFNLCRNSASSPKAAEAARLLLSDMWASKELQSVLRQQGFDRNMMGNIAGANNFRNFTSRF", "length": 728 }, "evidence": [ { "id": "G3N156", "url": "https://omabrowser.org/oma/group/G3N156/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LGN8-1", "protein_name": "Plakophilin-1", "gene_name": "PKP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVRRQKSKSSQSSTLSHSNRGSLYDGLADNYNNYGTASRGSYYTKFQAGNGSWGYPIYNGTLKREADNRRFSSYSQMESWGRNYPRSGCHAPGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLSSKGHKTTQNRYSFYSTCSGQKAVKKYPVCPPSCTPKPDPVYIPPVSCSKDLSFNHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKCQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVELLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLGRTRSTEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWRDGNSNLSRDTVDPEVFFNATGCLRNLSSADAGRQTMRNYTGLIDSLMAYVQNCVAASRCDDKSVENCMCILHNLSYRLDAEVPTRYRQLDYNARNTYTEKSSTGCFSNKSDRMMNNNYDCPLPEEEPNPKGSSWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPVLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQMAKQYFSSNMINNVINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGAFPGANTFRNFTSRF", "length": 727 }, "evidence": [ { "id": "G3N156", "url": "https://omabrowser.org/oma/group/G3N156/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97350-1", "protein_name": "Plakophilin-1", "gene_name": "Pkp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYNNYGTTSRSSYFSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCATPGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGHKTTQNRCSFYSTCSGQKAVKKCPVRPPSCTSKQDPVYVPPISCNKDLSFGHSRASSKICSEDIECSGLTIPKAVQYLCSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTPNKLETRRQNGIREAVSLLRRSGSTEIQKQLTGLLWNLSSTDELKEELVADALPVLTDRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCILHNLSYRLDAEVPTRYRQLEYNTRNAYTEKSSTGCFSNRGDKMMNNNYDCPLPEEETNPKGSSWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSNGMSQLIGIKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPVLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMTSQPQMAKQYFSNSMLNNVFNLCRNTASSPKAAEAARLLLSDMWASKELQSVLRQQGFDRNMMGNIAGANNLRNFTSRF", "length": 728 }, "evidence": [ { "id": "G3N156", "url": "https://omabrowser.org/oma/group/G3N156/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13835-1", "protein_name": "Plakophilin-1", "gene_name": "PKP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF", "length": 747 }, "evidence": [ { "id": "G3N156", "url": "https://omabrowser.org/oma/group/G3N156/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cell-cell adhesion", "id": "GO:0022409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022409", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "positive regulation of protein localization to membrane", "id": "GO:1905477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905477", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "G3N156", "url": "https://www.uniprot.org/uniprotkb/G3N156" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N156-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 727, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N156-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N156" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 554, "end_pos": 556 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 722, "end_pos": 724 } ] }, "class_list": [], "section_stats": [ { "table_id": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047874", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100299693", "url": "https://www.ncbi.nlm.nih.gov/gene/100299693", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100299693", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299693", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERSHKHD", "url": "https://omabrowser.org/oma/group/ERSHKHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N166", "url": "https://www.orthodb.org/?gene=G3N166", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002686205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N166", "url": "https://www.uniprot.org/uniprotkb/G3N166", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N166-1", "url": "https://www.uniprot.org/uniprotkb/G3N166-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAAAQQQQQCGSGGTTKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGTEEIDRHAERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRHSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNDREKERSRERSKERRSRGEVEEKKHKEDKDDRRHRDDKKDSKKERKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNDSKEKSNKRSRSGSQGRTDSVEKRKREHSPSKEKSRKRSGSKERSHKRDHSDSKDQSDKRDRRRSQSIETESQEKQHKDKEETV", "length": 543, "header": "tr|G3N166-1|G3N166_BOVIN Isoform 1 of Pre-mRNA-splicing factor 38B OS=Bos taurus OX=9913 GN=PRPF38B PE=3 SV=1 CANONICAL=G3N166-1" }, "isoforms": [ { "isoform_ac": "G3N166-1", "url": "https://www.uniprot.org/uniprotkb/G3N166/entry", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAAAQQQQQCGSGGTTKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGTEEIDRHAERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRHSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNDREKERSRERSKERRSRGEVEEKKHKEDKDDRRHRDDKKDSKKERKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNDSKEKSNKRSRSGSQGRTDSVEKRKREHSPSKEKSRKRSGSKERSHKRDHSDSKDQSDKRDRRRSQSIETESQEKQHKDKEETV", "length": 543, "header": "tr|G3N166-1|G3N166_BOVIN Isoform 1 of Pre-mRNA-splicing factor 38B OS=Bos taurus OX=9913 GN=PRPF38B PE=3 SV=1 CANONICAL=G3N166-1" }, "locus": { "chromosome": "3", "start_pos": 34681037, "end_pos": 34673912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063261.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063261.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055594.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055594.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100299693", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299693", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BVP9-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "PRPF38B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANNSPAVGAGNCQGQQAAQHQPGAVPPAQQQLQSGAPKPAASGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKTIDQQIKSRPRKIKKDGKEGMEEIDRHPERRRSRSPRRSLSPRRSPRRSRSRSHHREAHGSSSFDRELERERERQRLEREAKEREKERRRSRSTDRALERRRSRSRERYRSRSRSRDRKGERRDRDREREKENERSRKKERDYDKDRGSEREKDSDRSRERSKERKSKGDTEERRHRDDKDDKKHRDDKRDSKKERKHSRSRSRERKHRSRSRSKNTGKRSRSRSKEKSSKHKSESKEKSNKRSRSRSRGRTDSVEKSRKRDHSPSKERSRKRSRSKERSHKHDHSDSKDHSDKHDRRRSQSTERESQEKQQKNKDETV", "length": 549 }, "evidence": [ { "id": "G3N166", "url": "https://omabrowser.org/oma/group/G3N166/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q54J00-1", "protein_name": "Pre-mRNA-splicing factor 38", "gene_name": "prpf38b", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSLETFGNEKSMNLDNVLLTNIQSSLYFKNLYPKRSYHEVIEEIKRNVEILAPYIPNTKTPSTTFCLLYKFFLMKLTVKQMKGLLGNNESPYIRAIGALYLRYCHPPANLWDWYVDYLDDQETVFISKNTEVTIQRFLLDLLKDNKFSGTVLPRIPTKIQQDLDKKIKDYEIENNLTYNNNNNNTKKDSYSRDNRDNRDNRDSRDSRDSRDSRDNYRYSRDSRDSRDSRDNHRDSYRDRDSYSRDRDRDNRDSYRDNYRDSYRNNSRYNNDDNGKDSYAEELERFKNERNKSSGSGGRNYSKRDDYDDYSKSRSNDRDRDRDYSSSSGGNGNGYKRDSYYSDDDDDSEDGRTYGGRKRSRSRSNSRDRDSKNNSTQKETTTTTTTATTTTEKQPKEESESLKKLRSLYGATSDQVSLD", "length": 418 }, "evidence": [ { "id": "G3N166", "url": "https://omabrowser.org/oma/group/G3N166/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5VTL8-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "PRPF38B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAAAQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV", "length": 546 }, "evidence": [ { "id": "G3N166", "url": "https://omabrowser.org/oma/group/G3N166/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AXY7-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "Prpf38b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAVVQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGVEEIDRHIERRRSRSPRRSLSPRRSPRRSRSRSHHRDGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSLDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKDRGNDRERDRERSRERSKEQRSRGEGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKDKASKHKNESKEKSNKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKRDHDSKDQSDRQDHQRSQSVEPESQEKEHKNKDETV", "length": 542 }, "evidence": [ { "id": "G3N166", "url": "https://omabrowser.org/oma/group/G3N166/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80SY5-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "Prpf38b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAVTQQQQQCGGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGIEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGSDRERDRERSRERSKEQRSRGDGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRNAGKRSRSRSKDKSSRHKNESKEKANKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKREHNDSKDQSDRQDHQSSQSGEPESQEKEHKSKDETV", "length": 542 }, "evidence": [ { "id": "G3N166", "url": "https://omabrowser.org/oma/group/G3N166/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "G3N166", "url": "https://www.uniprot.org/uniprotkb/G3N166" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "G3N166", "url": "https://www.uniprot.org/uniprotkb/G3N166" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N166-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 543, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N166-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N166" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 459, "end_pos": 461 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N168-1", "uniprot_ac": "G3N168", "uniprot_id": "G3N168_BOVIN", "mass": { "chemical_mass": 43577.0, "monoisotopic_mass": 43577.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3N168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N168/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N168", "url": "https://www.uniprot.org/uniprotkb/G3N168" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3N168", "locus": {} } ], "crossref": [ { "id": "G3N168", "url": "https://alphafold.ebi.ac.uk/entry/G3N168", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047904", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N168", "url": "https://www.orthodb.org/?gene=G3N168", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46048:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46048:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3296197", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3296197", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-373076", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-373076", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N168", "url": "https://www.uniprot.org/uniprotkb/G3N168", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N168-1", "url": "https://www.uniprot.org/uniprotkb/G3N168-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFFISCIRLTLLDMKCGSLCLFGRFHLRSEKNCCVFRDDFIAKVLPPVVGLEFVFGLLGNGLALWIFCFHLKSWKASRVFLFNLAVADFLLIICLPFLADNYVRRWDWKFGEIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAGIISCLLWGITIGLTVHLLHRTRLIENQGSKLCSSFSICDAFRWHDAMFLLEFFVPLGIILFCSVRIVWSLRQRQMNKHAKIRRAINFIMVVAIVFIICFLPSVAVRIHIFWLLRKAGTENCDIYRSVDLAFYITLSFTYMNSMLDPLVYYFSSPSFPNFFSTLINRCLKRKGPDESDNNRSTSVELTGDLSTTKNVPEALMANPSEPQSPSYLNPVSS", "length": 379, "header": "tr|G3N168-1|G3N168_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3N168-1" }, "isoforms": [ { "isoform_ac": "G3N168-1", "url": "https://www.uniprot.org/uniprotkb/G3N168/entry", "sequence": { "sequence": 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initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376981" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N185", "url": "https://www.uniprot.org/uniprotkb/G3N185#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N185", "url": "https://www.uniprot.org/uniprotkb/G3N185" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5P4", "url": "https://www.uniprot.org/uniprotkb/G3N185", "locus": { "chromosome": "15", "start_pos": 44957698, "end_pos": 44958636, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000065703", "url": "https://www.ensembl.org/id/ENSBTAG00000065703" } ] } } ], "crossref": [ { "id": "G3N185", "url": "https://alphafold.ebi.ac.uk/entry/G3N185", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000054054", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054054", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "523139", "url": "https://www.ncbi.nlm.nih.gov/gene/523139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523139", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523139", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NYSADQV", "url": "https://omabrowser.org/oma/group/NYSADQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N185", "url": "https://www.orthodb.org/?gene=G3N185", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376981", "database": "RefSeq", 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"evidence": [ { "id": "G3N185", "url": "https://omabrowser.org/oma/group/G3N185/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N185", "url": "https://www.uniprot.org/uniprotkb/G3N185" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N185", "url": "https://www.uniprot.org/uniprotkb/G3N185" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "G3N185", "url": "https://www.uniprot.org/uniprotkb/G3N185" } ], "pmid": "" } ] }, { "name": "Cellular 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"end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N185-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N185" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N185" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1C8-1", "uniprot_ac": "G3N1C8", "uniprot_id": "G3N1C8_BOVIN", "mass": { "chemical_mass": 487551.0, "monoisotopic_mass": 487551.0 }, "refseq": { "ac": "XP_024839013", "name": "dynein axonemal heavy chain 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839013" }, "gene_names": [ { "name": "DNAH1", "type": "recommended", "evidence": [ { "id": "G3N1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1C8" } ] }, { "name": "DNAH1", "type": "synonym", "evidence": [ { "id": "XP_024839013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839013" } ] } ], "protein_names": [ { "name": "Dynein axonemal heavy chain 1", "type": "recommended", "evidence": [ { "id": "G3N1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1C8/entry#names_and_taxonomy" } ] }, { "name": "Axonemal beta dynein heavy chain 1", "type": "synonym", "evidence": [ { "id": "G3N1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1C8/entry#names_and_taxonomy" } ] }, { "name": "Ciliary dynein heavy chain 1", "type": "synonym", "evidence": [ { "id": "G3N1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1C8/entry#names_and_taxonomy" } ] }, { "name": "dynein axonemal heavy chain 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024839013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839013" } ] } ], "function": [ { "annotation": "Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme.", "evidence": [ { "database": "UniProtKB", "id": "G3N1C8", "url": "https://www.uniprot.org/uniprotkb/G3N1C8#function" }, { "database": "UniProtKB", "id": "ARBA00055289", "url": "https://www.uniprot.org/uniprotkb/ARBA00055289#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1C8", "url": "https://www.uniprot.org/uniprotkb/G3N1C8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DNAH1", "url": "https://www.uniprot.org/uniprotkb/G3N1C8", "locus": { "chromosome": "22", "start_pos": 48488242, "end_pos": 48565274, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047794", "url": "https://www.ensembl.org/id/ENSBTAG00000047794" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047794", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047794", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540601", "url": "https://www.ncbi.nlm.nih.gov/gene/540601", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR004273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041589", "url": 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"id": "PF17857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024839013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839013", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N1C8", "url": "https://www.uniprot.org/uniprotkb/G3N1C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1C8-1", "url": "https://www.uniprot.org/uniprotkb/G3N1C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 4266, "header": "tr|G3N1C8-1|G3N1C8_BOVIN Isoform 1 of Dynein axonemal heavy chain 1 OS=Bos taurus OX=9913 GN=DNAH1 PE=1 SV=3 CANONICAL=G3N1C8-1" }, "isoforms": [ { "isoform_ac": "G3N1C8-1", "url": "https://www.uniprot.org/uniprotkb/G3N1C8/entry", "sequence": { "sequence": "MEQPNREGHSPGRASQGQECRWTSAGPECNLKDLERDPGRILQGPDSGSQKLPPSPDPKTPPLPLSVTPPMPSDLGQPRKLPLTGSDKKYPLMKQRGFYSDILSPGSLDKLGEVCHGPCTNLDLLWQANLDKFTPEVRTFEVSEDFEERLERERIGSTTKLLTQTDFPLQAYEPKVQVPYMVLPGQCPRKIEIERRKQLYLSLDIEQLLANEGIDSDKLMPRHPDPHNPQTIEQGHDPLFPIYLPLKVFDNEEFDCRTPTEWINMGLEPGSENRKPVPGKALLPTDDFLGHEDPKSQKLKYEWCSVGVLDYDKENKLYLVHKTSEDGLVRDETGKPILNGGVTPEGRSPLLICQYWVPRIQLLFCAEDPRVFTRRVVEANALRKNTEALLLYNLYVDCMPSEGQRLVSEQSLNKIKQWAMSTPRMRKGPAVLEHLSNLSREVNLDYERSMNKINFDKIVSSKPETFSYVTLPKKEEEKVPKQGLVSVPRYPFLEQKADFTFVSLLTRSEVITALSKVRAECNKVTTMSLFHSSLSKYSRLEEFEQIQSQTFSQVQMFLKDSWISTLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELLKYMLQDTLRFLVQDSLASFSQFISDACCSVLGCADDMVWGEDLINSPYRPRKNPLFIVDLMLDTSGVHYSTPLEQFETSLLTLFDKGILATHTVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRAVIANAVRKAMIPLQAYAKEFRKYLELNNNDVNTFLKAFQTQCPSAEEVREVVLTHLHEKEVLDSSLPSSIIIGPFYINVDNVKQSLSKKRKALATSMLDILAKNLHREVDNICEEFRSISRKIYEKPNSIEELAELREWMKGVPEKLVGLEERIVKIMGDYQVMDEFLYNLSTEDFNDKWAASNWPTKILGQIELVRQQHLEDEEKFRKIQLMDQNNFQEKLEGLQLVVAGFSTHVEILRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFGLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVIESFKTMHKCVKQFKDIPACQDVALDIRARIEEFKPYIPLIQGLRNPGMRNRHWDVLSSEININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVMPYKETDTYILKSPDEASQLLDDHIVMTQSMSFSPYKKPFEQRINSWETKLKLTQEVLEEWLNCQRAWLYLEPIFSSEDINRQLPVESKRYQTMERIWRKIMKNAYENREVINVCSDQRLLDSLRDCNKLLDMVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIAQLLFQEDLEITHMYSAEGEEVQLSFSIYPSSNVEDWLREVENSMKASVRDIIERAIKAYPRMLRTQWVLNWPGQVTIAGCQTYWTLEVEEALEAGNLSSRLFPQLARQLSDLVALVRGSLSRMQRAVLSALIVIEVHAKDVVHKLVQENVVSVHDFEWISQLRYYWMNNNLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMIAEISLYSFGFNEANVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMDEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEETDYGILDKAIRKACEKSNLKDVDGFLTKCIQLYETTVVRHGLMLVGPTGSGKSNCYRVLAAAMTSLKGQPSISGGVYEAVSYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSLIRMGAITSDTSKKWYMFDGPVDAVWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFVECWLRRIPALLRPFEEQFKSLFISFLEESLAFVRSSVKEVIASTNSNLTTSLLKLLDCFFKPFLPKEGLKKMPPEKLSRIPELIEPWFIFSLIWSVGATGDSTSRNNFSHWLRIKMKTENVALLFPEEGLVFDYRLEDGGISSTSDDDDEEEEGKQVAWVKWMDSSTTFTMMPDTNYCSIIVPTTDTIQMSYLLDMLLTNHKPVLCIGPTGTGKTLTISNKLLKNLPLEYISHFLTFSARTSANQTQDLIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKQLVDINFVCAMGPPGGGRNAITPRLTRHFNYLSFAEMDEVSKKRIFSTILGSWVDGLLGEKSYREPVPGAPNIAHFTDPLVEATIMVYSTITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDKVQLLRLWYHENCRVFRDRLVNDEDRGWFDKLLESHMDEWEVGFEEVCPFQPILYGDFMSPGSDVKSYELITNERKMMQVIEEYMDDYNQINTAKLRLVLFMDAMSHVCRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEFECFQIELSKNYGMTEWRDDVKKVLLKAGLHNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYNMDEQDQIMNTMRPYIQEQGLQPTKANLMAAYTGRVRSSIHLVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALESVAIMFLSEIPELDATPKVIEGLIQVCVYIHQSVAKKCVEYLAELARHNYVTPKSYLELLNIFSILVGQKKQELKTAKNRMKSGLDKLLRTAEDVAKMQEELEIMRPLLEEAARDTTLTMEQIKVDTAIAEETRNSVQAEEIKANEKARKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGSKVDDYWEPGKGLLQDPGRFLESLFKFDKDNIGEAVIKAIQPYIDNEEFQPAAIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALREAQDDLEVTQRILEEAKQRLHEVEDGIATMQAKYRECIAKKEELELKCEQCEQRLGRADKLINGLSDERVRWQETVESLEHMLDSIFGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQLVAHRVPHTAEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQGQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFKMYITTKLPNPHYTPEISTRLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIVSNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYVPVAVRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRIANINHYLTYNLYSNVCRSLFEKHKLMFAFLLCARIMMNQGKINQNEWRYLLSGGSVSVLSENPAPDWLTDRAWRDIQALSNLPAFSSFTHDFVKHLPEFQAIFDSHEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVAANLEPRFIEPQTANLSLVFKDSNPTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPVLERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVKANLLKSYSSLSDEFLNSCHKVMEFKCLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDHIPYKVLKYTAGEINYGGRVTDDWDRRCVMNILEDFYSPEVLFPEHSYSASGVYHQIQPTYDLNGYLSYVKSLPLNDMPEIFGLHDNANITFAQNETYTLLGTIVQLQPKSSTAGGQSREEIVEDVAQNILIKVPDPVNLQWVMTKYPVLYEESMNTVLAQEVIRYNRLLQVITQSLRDLLKALKGLVVMSSQLELMAASLYNNSVPELWKAKAYPSLKPLSSWVLDLLQRLDFLQTWISEGIPAVFWISGFFFPQAFLTGTLQNYARKSVISIDTISFDFKVMRESVSELKTRPKEGCFIHGLFLEGARWDPLAFQLAESRPKELYTEMAVIWLLPTPNRKVQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTDQPQRHWIKRGVALICALDY", "length": 4266, "header": "tr|G3N1C8-1|G3N1C8_BOVIN Isoform 1 of Dynein axonemal heavy chain 1 OS=Bos taurus OX=9913 GN=DNAH1 PE=1 SV=3 CANONICAL=G3N1C8-1" }, "locus": { "chromosome": "22", "start_pos": 48565239, "end_pos": 48488288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066095.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066095.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055667.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055667.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1865, "start_aa": "Thr", "end_pos": 1865, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1865", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2230, "start_aa": "Thr", "end_pos": 2230, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2230", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2355, "start_aa": "Thr", "end_pos": 2355, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2355", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2431, "start_aa": "Thr", "end_pos": 2431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2431", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2804, "start_aa": "Thr", "end_pos": 2804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2804", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "G3N1C8", "url": "https://www.uniprot.org/uniprotkb/G3N1C8" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [ { "id": "bta:540601", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540601", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3N1C8", "url": "https://www.uniprot.org/uniprotkb/G3N1C8" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "G3N1C8", "url": "https://www.uniprot.org/uniprotkb/G3N1C8" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "G3N1C8", "url": 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taurus OX=9913 GN=RHBDD2 PE=3 SV=1 CANONICAL=G3N1D6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NU88-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NU88/entry", "sequence": { "sequence": "MLGVNCVRSRMRRALVFGVVVPSLLVPWLLLCASWLIPQTSFLSNVCGLGIGLAYGLTYCFSFDVPEQVAVKLDQKFPFSLMRRISMFKYISGSSAERRAAQSRKPNPVPGSYPTQSGHPHLTPNHPAAQMQHASSQKLAAWPSCAPGHMPSLPPYQPASGLCYVQNHFGTTPNSSGVYPASAGASLGVQPPAPLNCPGTVYSGALATPAAAGSKECSRVLMS", "length": 223, "header": "tr|A0ABI0NU88-1|A0ABI0NU88_BOVIN Computationally mapped isoform of Rhomboid domain containing 2 OS=Bos taurus OX=9913 GN=RHBDD2 PE=4 SV=1 CANONICAL=G3N1D6-1" }, "locus": { "chromosome": "25", "start_pos": 34128917, "end_pos": 34124043, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142387.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142387.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107185.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107185.1" } ] } }, { "isoform_ac": "G3N1D6-1", "url": 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scrofa", "sequence": { "sequence": "MAVSEPGYRSWSLWPEVPSATFFTALLSLLVSGPRLFLLQPPLAPSGLSLRSEALRNWQVYRLVTYIFVYENPVSLLCGAIIIWRFAGNFERTVGTVRHCFFTVIFALCSAIIFLSFEAVSKLSKLGEVEDARGFTPVAFAMLGVNSVRARMRRALVFGMVVPSMLVPWLLLCASWLIPQTSFLSNVCGLGIGLAYGLTYCYSLDLPEHVALKLDQKFPFSLMRRISLFKYISGSSAERRAAHSRRLNPVPGSYPTQSGHPHLPPNHPVAQMQHASGQKLASWPACAPGHMPSLPPYQPASGLCYVQNHFGTTPNSSGVYPASAGASLGVQPPAPLNCPGTVYSGALATPAAAGSKECSRVLIP", "length": 364 }, "evidence": [ { "id": "G3N1D6", "url": "https://omabrowser.org/oma/group/G3N1D6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZQG3-1", "protein_name": "Rhomboid domain-containing protein 2", "gene_name": "Rhbdd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377447" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N1D7", "url": "https://www.uniprot.org/uniprotkb/G3N1D7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1D7", "url": "https://www.uniprot.org/uniprotkb/G3N1D7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2T13", "url": "https://www.uniprot.org/uniprotkb/G3N1D7", "locus": { "chromosome": "8", "start_pos": 58566, "end_pos": 59504, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000050937", "url": "https://www.ensembl.org/id/ENSBTAG00000050937" } ] } } ], "crossref": [ { "id": "G3N1D7", "url": "https://alphafold.ebi.ac.uk/entry/G3N1D7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787816", "url": "https://www.ncbi.nlm.nih.gov/gene/787816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"MENGSYTSYFILLGLFNHTRAHQVLFMMVLSIVLTSLFGNSLMILLIHWDHRLHTPMYFLLSQLSLMDVMLVSTTVPKMAADYLTGSKAISRAGCGAQIFFLPTLGGGECFLLAAMAYDRYAAVCHPLRYPTLMSWQLCLRMNLSCWLLGAADGLLQAVATLSFPYCGAHEIDHFFCETPVLVRLACADTSVFENAMYICCVLMLLVPFSLILSSYGLILAAVLHMRSTEARKKAFATCSSHVAVVGLFYGAAIFTYMRPKSHRSTNHDKVVSAFYTMFTPLLNPLIYSVKNSEVKGALTRCMGRCVALSRE", "length": 312 }, "evidence": [ { "id": "G3N1D7", "url": "https://omabrowser.org/oma/group/G3N1D7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N1D7", "url": "https://www.uniprot.org/uniprotkb/G3N1D7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N1D7", "url": "https://www.uniprot.org/uniprotkb/G3N1D7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N1D7", "url": "https://www.uniprot.org/uniprotkb/G3N1D7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G3N1D7", "url": "https://www.uniprot.org/uniprotkb/G3N1D7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"uniprot_ac": "G3N1M3", "uniprot_id": "G3N1M3_BOVIN", "mass": { "chemical_mass": 35512.0, "monoisotopic_mass": 35512.0 }, "refseq": { "ac": "NP_001376866", "name": "olfactory receptor family 8 subfamily K member 3B", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376866" }, "gene_names": [ { "name": "OR8K3B", "type": "recommended", "evidence": [ { "id": "G3N1M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1M3" } ] }, { "name": "OR8K3B", "type": "synonym", "evidence": [ { "id": "NP_001376866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376866" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3N1M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1M3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 8 subfamily K member 3B", "type": "synonym", "evidence": [ { "id": "NP_001376866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376866" } ] }, { "name": "olfactory receptor, family 8, subfamily K, member 3-like", "type": "synonym", "evidence": [ { "id": "NP_001376866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376866" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376866" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N1M3", "url": "https://www.uniprot.org/uniprotkb/G3N1M3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1M3", "url": "https://www.uniprot.org/uniprotkb/G3N1M3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8K3B", "url": "https://www.uniprot.org/uniprotkb/G3N1M3", "locus": { "chromosome": "15", "start_pos": 79151995, "end_pos": 79151054, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000058228", "url": "https://www.ensembl.org/id/ENSBTAG00000058228" } ] } } ], "crossref": [ { "id": "G3N1M3", "url": "https://alphafold.ebi.ac.uk/entry/G3N1M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048987", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048987", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15413", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15413", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514057", "url": "https://www.ncbi.nlm.nih.gov/gene/514057", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514057", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514057", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNNICNI", "url": "https://omabrowser.org/oma/group/WNNICNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N1M3", "url": "https://www.orthodb.org/?gene=G3N1M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376866", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N1M3", "url": "https://www.uniprot.org/uniprotkb/G3N1M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1M3-1", "url": "https://www.uniprot.org/uniprotkb/G3N1M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METHNGTVLSEFILMGITDRPELQAPLFGLFLIIYMISAVGNLGMVILTKVDSRLRTPMYFFLRHLALTDLGYSTSVGPQMLVNFVVDQNKISYHLCATQLAFFIVFIISELFILATMSYDRYVAICHPLLYTVIMSQRVCWALVAIPYLYSTLVSLLVTVNIFNSSFCGYNIISHFYCDSLPILSLLCSNTHEIELIILVLSGFNLIFSLLIVLVSYLLILAAIVRMNSTEGRRKAFSTCGSHLTVVTVFYGTLIFMYVQPESSHSFDTDKVASIFYTLVIPMLNPLIYSLRNKDVKYALQRTWKKLCNIFP", "length": 313, "header": "tr|G3N1M3-1|G3N1M3_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8K3B PE=3 SV=1 CANONICAL=G3N1M3-1" }, "isoforms": [ { "isoform_ac": "G3N1M3-1", "url": "https://www.uniprot.org/uniprotkb/G3N1M3/entry", "sequence": { "sequence": "METHNGTVLSEFILMGITDRPELQAPLFGLFLIIYMISAVGNLGMVILTKVDSRLRTPMYFFLRHLALTDLGYSTSVGPQMLVNFVVDQNKISYHLCATQLAFFIVFIISELFILATMSYDRYVAICHPLLYTVIMSQRVCWALVAIPYLYSTLVSLLVTVNIFNSSFCGYNIISHFYCDSLPILSLLCSNTHEIELIILVLSGFNLIFSLLIVLVSYLLILAAIVRMNSTEGRRKAFSTCGSHLTVVTVFYGTLIFMYVQPESSHSFDTDKVASIFYTLVIPMLNPLIYSLRNKDVKYALQRTWKKLCNIFP", "length": 313, "header": "tr|G3N1M3-1|G3N1M3_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR8K3B PE=3 SV=1 CANONICAL=G3N1M3-1" }, "locus": { "chromosome": "15", "start_pos": 79151992, "end_pos": 79151054, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063956.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063956.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055771.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055771.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514057", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514057", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K186-1", "protein_name": "Olfactory receptor family 8 subfamily K member 25", "gene_name": "Or8k25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTISNGEIQSQTLTEFILMGITYHAELQVPLFGLFLIIYLTSLVGNLGMIILTMMDCRLQTPMYFFLRHLATTDLGYSTAVGPKMLSNFLVDQNTISFQDCAIQSAFFSMFIVSEFFILSAMFYDHYVAICKPLLYTIIVSQKVCWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVINHFYCDALPLLSLACSNTHEIEVIILVFSAFNLLLSLLKVIGSYLLILKAILSINSAEGKRKAFSTCGSHLTVVIVFYGTLIFMYLQPASTHSIDSNKVTSIFYTQVIPMLNPLIYSLRNKDVKDALKKTMEKVHNLVS", "length": 317 }, "evidence": [ { "id": "G3N1M3", "url": "https://omabrowser.org/oma/group/G3N1M3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2LD79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100753427", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQTHNLTVVTEFILMGITDRPELQAPLFGVFLIIYLISLVGNFGMIILTLMDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNTISFYFCAIQLSFFNMFIVSEFFILSAMSYDRYVAICKPLQYTVIMSQRVCWILVTIPYLYGIIVSLLLTIKIFSVSFCGHNVISHFYCDGLPLLFLACSNTHEIEVIILILSAFNLLSSLLIVILSYLFILTAILRMNSAEGKRKAFSTCGSHLTVVIVFYGTLIFMYLQPMSIHSFDADKVTSIFYTQVIPMLNPLIYSLRNKDVKDAFKNSVDKLLNIVL", "length": 313 }, "evidence": [ { "id": "G3N1M3", "url": "https://omabrowser.org/oma/group/G3N1M3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2AK62-1", "protein_name": "Olfactory receptor family 8 subfamily K member 28", "gene_name": "Or8k28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTMVTEFILVGITYHPEFQVPLFGLFLIIYLTSLFGNLGMIILTMVDSGLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNTISFNACDIQSSFFSMFIVCEFFILSALSYDCYVAICKPLLYTVIMSQKVCWILVTIPYLYSIIVSLIINIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSTEGKWKAFSTCGSHLTVVIVFYGTLICMYLQPTSTHSIDTGKGTSIFYTQVIPMLNPLIYSLRNKDVTDVLKKTKEKVYNLVS", "length": 313 }, "evidence": [ { "id": "G3N1M3", "url": "https://omabrowser.org/oma/group/G3N1M3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N1M3", "url": "https://www.uniprot.org/uniprotkb/G3N1M3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N1M3", "url": "https://www.uniprot.org/uniprotkb/G3N1M3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N1M3", "url": "https://www.uniprot.org/uniprotkb/G3N1M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1M3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1M3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1M3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1M3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1P6-1", "uniprot_ac": "G3N1P6", "uniprot_id": "G3N1P6_BOVIN", "mass": { "chemical_mass": 100852.0, "monoisotopic_mass": 100852.0 }, "refseq": {}, "gene_names": [ { "name": "ANAPC2", "type": "recommended", "evidence": [ { "id": "G3N1P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1P6" } ] } ], "protein_names": [ { "name": "Anaphase-promoting complex subunit 2", "type": "recommended", "evidence": [ { "id": "G3N1P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1P6/entry#names_and_taxonomy" } ] }, { "name": "Cyclosome subunit 2", "type": "synonym", "evidence": [ { "id": "G3N1P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1P6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.", "evidence": [ { "database": "UniProtKB", "id": "G3N1P6", "url": "https://www.uniprot.org/uniprotkb/G3N1P6#function" }, { "database": "UniProtKB", "id": "ARBA00054244", "url": "https://www.uniprot.org/uniprotkb/ARBA00054244#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1P6", "url": "https://www.uniprot.org/uniprotkb/G3N1P6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANAPC2", "url": "https://www.uniprot.org/uniprotkb/G3N1P6", "locus": { "chromosome": "11", "start_pos": 106201443, "end_pos": 106211008, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046223", "url": "https://www.ensembl.org/id/ENSBTAG00000046223" } ] } } ], "crossref": [ { "id": "G3N1P6", "url": "https://alphafold.ebi.ac.uk/entry/G3N1P6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046223", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046223", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR014786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AAKWQES", "url": "https://omabrowser.org/oma/group/AAKWQES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45957:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45957:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174048", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176412", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N1P6", "url": "https://www.uniprot.org/uniprotkb/G3N1P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1P6-1", "url": "https://www.uniprot.org/uniprotkb/G3N1P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAVPRRPNRRCRPPRRLRTISARPAPSSVTAPAPLAAHRVRHRRACAPSPASSRRASPSGSEGWWSQMAAAAEAGRDAGPAQELLAAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQTDLQANISLEFWNAISQRENCADEPQCLLLLLDAFGLLESRLDPYLRSLELLEKWTRLGLLMGTGAQGLREKVHTTLRGVLFFSTPRAFQEMIQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQRCWCRQALEQFHRLSQVLHRLSLLERVSAEAVTSTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQDGPSRPASPEPGTTLRRWRCHVQRFFYRIYAGLRIEELFSIIRDFPDSRPAVEDLKYCLERTDQRPQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVVLEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIREALEVYCRKYEKLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVVLLYFQDQASWGLEELSEAVKMPAALLRRRLSVWLQQGVLREEPAGTFSVVEEERPQDRDNMVLVDSDDESDSGLASQADQKEEELLLFWTYIQAMLTNLESLSLERIYSMLRMFVVTGPALAEIDLQELQGFLQRKVRDQQLVYSAGVYRLPKSCG", "length": 888, "header": "tr|G3N1P6-1|G3N1P6_BOVIN Isoform 1 of Anaphase-promoting complex subunit 2 OS=Bos taurus OX=9913 GN=ANAPC2 PE=3 SV=2 CANONICAL=G3N1P6-1" }, "isoforms": [ { "isoform_ac": "G3N1P6-1", "url": "https://www.uniprot.org/uniprotkb/G3N1P6/entry", "sequence": { "sequence": "MVAAVPRRPNRRCRPPRRLRTISARPAPSSVTAPAPLAAHRVRHRRACAPSPASSRRASPSGSEGWWSQMAAAAEAGRDAGPAQELLAAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQTDLQANISLEFWNAISQRENCADEPQCLLLLLDAFGLLESRLDPYLRSLELLEKWTRLGLLMGTGAQGLREKVHTTLRGVLFFSTPRAFQEMIQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQRCWCRQALEQFHRLSQVLHRLSLLERVSAEAVTSTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQDGPSRPASPEPGTTLRRWRCHVQRFFYRIYAGLRIEELFSIIRDFPDSRPAVEDLKYCLERTDQRPQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVVLEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIREALEVYCRKYEKLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVVLLYFQDQASWGLEELSEAVKMPAALLRRRLSVWLQQGVLREEPAGTFSVVEEERPQDRDNMVLVDSDDESDSGLASQADQKEEELLLFWTYIQAMLTNLESLSLERIYSMLRMFVVTGPALAEIDLQELQGFLQRKVRDQQLVYSAGVYRLPKSCG", "length": 888, "header": "tr|G3N1P6-1|G3N1P6_BOVIN Isoform 1 of Anaphase-promoting complex subunit 2 OS=Bos taurus OX=9913 GN=ANAPC2 PE=3 SV=2 CANONICAL=G3N1P6-1" }, "locus": { "chromosome": "11", "start_pos": 106210989, "end_pos": 106201505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064659.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064659.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055798.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055798.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 261, "start_aa": "Thr", "end_pos": 261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr261", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 726, "start_aa": "Thr", "end_pos": 726, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr726", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-BTA-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-BTA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-BTA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-BTA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-BTA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-BTA-176407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176407", "resource": "Reactome", "description": "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" }, { "id": "R-BTA-176408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176408", "resource": "Reactome", "description": "Regulation of APC/C activators between G1/S and early anaphase" }, { "id": "R-BTA-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of mitotic proteins" }, { "id": "R-BTA-176412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176412", "resource": "Reactome", "description": "Phosphorylation of the APC/C" }, { "id": "R-BTA-179409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-179409", "resource": "Reactome", "description": "APC-Cdc20 mediated degradation of Nek2A" }, { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2559582", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559582", "resource": "Reactome", "description": "Senescence-Associated Secretory Phenotype (SASP)" }, { "id": "R-BTA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-BTA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4ISV4-1", "protein_name": "Anaphase-promoting complex subunit 2", "gene_name": "anapc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNEMQSVPQGLSVAWDTVTSSLVSPVQQNVSTAEALSDALSLLTEHGLGQYVEGWLLETLQVRLTTSVAPEFWTGLKQPEGDSQERDRAKALLDAFRNLLQQLEPFLGGLEKLGSWQEESCGDLCGPGPHGLIERAFSVIRAILLFSPPPVLQERMLEFYSRTFSVHMSQAGEAVEAEEGAVDTDEGGLCSGCATLPHLCWCQEALQQLQELSHILSRLQLLERVSSEAVTSILHQLIEQRMEQRYRGEYERSFLTDFNDWLGQVLGWLSRVFSSKADEVGSEITPIDGKMGQPANALLQRWHCHMHQFFCRIYVNMRIEELFSIIRDFPESTPAIEDLKFCLERTNQRQQLLASLKSAFETRLLHPGVHTSDIITVYISAIKALRELDPSMVILQVACQPIRKYLRTREDTVRQIVGSLTGDSEGCTDLANELSRADPVALETQDSEDEGSDPEDWTPDPTDALTDKTGSKRRSSDIISLLVSIYGSKEIFVNEYKTVLADRLLHQLNYNTAREIRNVELLKLRFGESHMHYCEVMLKDVADSRRINSNIHEEERRLPAEEQPTLPLSAMIISSEFWPQLKEEKMELPAVASKAMEDYTHRFEKLKAMRTLRWKPQLGSVTLDLELEDRTITDLTVSPIHAAIILHFQDKGTWTLEELSGVLGVPQEMVRRKLALWQQQGVLREEAGGRYTVQETSTCKERSERSVMLIDSDEEGDSNTATQSEQREEKLQLFWAYIQAMLTNLESMTLERIHSMLRMFVAAGPGVTEMDVNELQAFLQKKVRAHQLTVSTGVYRLPKITQ", "length": 802 }, "evidence": [ { "id": "G3N1P6", "url": "https://omabrowser.org/oma/group/G3N1P6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V1ADL6-1", "protein_name": "Anaphase-promoting complex subunit 2", "gene_name": "ANAPC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEISSVPLYRPHSPGLHQRGGNTFTVVPKRKPVASGLQGLTEAGGRPQREEEEEDEESKGRSKAVENADGPQVGPSHKKRYPTVNEIEVIGGYLSLERSCISKTGSRRKKAAARCDPVRPLQDAELRAALEVLRCYGLHAAVEEWFLEVLQTDLQAHIAPEFWNCVGQYENTAEEQQCSALLLDAFCLLKCRLEPYLSSMELLEGWTEAGLLLGTGAQTLREKVYTMFKAILFFSTTKPFQEMIQQFYSRTFRIYMRQWKKGEEGMNECESSMSEAEQESDTEEGGGESAVCAGCGSRREQCWCPTAMERFRQLNHILRRLNLLERVSADAVTTILHRMIKERMERRCRGEYEHSFLNEFQEWIEKVLGWLSRVFLQDGPLARPSAEASSTLRRWRCHVQRFFYRIYASMLIEELFSIIRDFPESKPAVEDLKFCLERTNLRQQLLSSLKSALEIRLLHPGVNTSDIITLYISAIKALRELDPSMVILEVACEPIRKYLRTREDTVRQIVAGLTGDAEGSGDLANELSKADPVTLENGQESDDDISEPGDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRTLLADRLLHQFNYSAEREIRNVELLKLRFGEAQMHYCEVMLKDMADSRRINANIRDEEEKLPEEERPPFSLVAVILSSEFWPPLKEEKLELPEQVKEAMEAYSKKYEKLKAMRTLNWKYHLGLVSLDVELADRTLSLSVSPVHAAIILHFQTKSTWTLAELSEVLKVPVTSLKRKMTLWLQQGVLREEPPGTFTVIEEEQKDQGEKVVLIDSDEEGDSAMASQADQKEEELQLFWTYIQAMLTNLESLSLERIHSMLKMFVMTGPVVTEIDIQELQGFLQKKVRDQQLIYSGGVYRLPKNCN", "length": 893 }, "evidence": [ { "id": "G3N1P6", "url": "https://omabrowser.org/oma/group/G3N1P6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4FQK7-1", "protein_name": "Anaphase-promoting complex subunit 2", "gene_name": "ANAPC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAEQQNDPGPAQELLVAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRSHGLHSVLEEWFVEVLQNDLQASIALEFWNTISQRENCADEPQCLLLLLDAFGLLESRLDPYLRSLELLEKWTRLGLLMGTGAQGLREKVHTTVRGVLFFSTPRPFQEMIQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQQCWCRQALEQFHHLSQVLHRLSLLERVSAEAVTSSLRQATRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQEGPSRPASAEAGSTLRRWRCHVQRFFYRIYAGLRIEELFSIIRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVSTCDIITLYISAIKALRALDPSMVVLDVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSSSRRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPPEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIREALEVYCRKYEKLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVVLLYFQDQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPAGTFSVVEEERPQDRDSMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLERIYSMLRMFVVTGPALAEIDLQELQGFLQKKVRDQQLVYAAGVYRLPKSCG", "length": 818 }, "evidence": [ { "id": "G3N1P6", "url": "https://omabrowser.org/oma/group/G3N1P6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7EWF8-1", "protein_name": "Anaphase-promoting complex subunit 2", "gene_name": "Anapc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BZQ7-1", "protein_name": "Anaphase-promoting complex subunit 2", "gene_name": "Anapc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005207245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207245", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1T8-1", "url": "https://www.uniprot.org/uniprotkb/G3N1T8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSEKSLTLAAPGEVHGPEGEQQDAGDFPEAGGGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGVDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNGGGVSPGSRGSQEEEEDEGDSYTFHPGIAPGGMVAGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQSATGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPAPDLKAADSGLGKPEFSEATRERRPSYLPTPHRGYAEKRMLTEV", "length": 528, "header": "tr|G3N1T8-1|G3N1T8_BOVIN Isoform 1 of Potassium voltage-gated channel subfamily A member 6 OS=Bos taurus OX=9913 GN=KCNA6 PE=4 SV=2 CANONICAL=G3N1T8-1" }, "isoforms": [ { "isoform_ac": "G3N1T8-1", "url": "https://www.uniprot.org/uniprotkb/G3N1T8/entry", "sequence": { "sequence": "MRSEKSLTLAAPGEVHGPEGEQQDAGDFPEAGGGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGVDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNGGGVSPGSRGSQEEEEDEGDSYTFHPGIAPGGMVAGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQSATGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPAPDLKAADSGLGKPEFSEATRERRPSYLPTPHRGYAEKRMLTEV", "length": 528, "header": "tr|G3N1T8-1|G3N1T8_BOVIN Isoform 1 of Potassium voltage-gated channel subfamily A member 6 OS=Bos taurus OX=9913 GN=KCNA6 PE=4 SV=2 CANONICAL=G3N1T8-1" }, "locus": { "chromosome": "5", "start_pos": 105369529, "end_pos": 105367946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065475.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065475.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055841.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055841.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 480, "start_aa": "Thr", "end_pos": 480, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr480", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZS40-1", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "gene_name": "KCNA6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRAEEPLALAAPQAGGGEAEATGEEQGGSGCCSSERLVINISGLRFETQLRTLSIFPDTLLGDPSRRVHYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVHVPLDIFLEEIRFYQLGQEAIETFREDEGFIQEEEKPLPEHHFQRQVWLLFEYPESSGPARAIAIVSVLVILISIVIFCLETLPEFRQEPKVTQPGFGELAVLDDDILLPPPPPSGTPQPPQPTAGAGPFFTDPFFLIETLCIIWFSFELLVRFFTCPSKPDFSRNIMNIIDIVAIIPYFITLGTELAQQQQQQSGSSSNNGGQQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAETDDPDSLFTSIPDAFWWAVVSMTTVGYGDMYPMTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDNEEQCQYTHVTCGQQQSLFSEPKKGNSNQSLSKSEFFEVEDLESMKYSNFIPPGNQGYKEKKMLTEV", "length": 513 }, "evidence": [ { "id": "G3N1T8", "url": "https://omabrowser.org/oma/group/G3N1T8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4FBH8-1", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "gene_name": "KCNA6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAAGGGGGGGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGVDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNGGGVGRGSPVSRGSQEEEEEEDDSYTFHPGITPGGMVAGGSSSLSTFGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQSASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPTPDLKAADNGLGKPEFPEATRERRPSYLPTPHRGYAEKRMLTEV", "length": 536 }, "evidence": [ { "id": "G3N1T8", "url": "https://omabrowser.org/oma/group/G3N1T8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GUK9-1", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "gene_name": "Kcna6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSEKSLTLAAPGEVRGPEGEQQDAGEFPEAAGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGEEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRMSPASRGSHEEEEEDEDSYAFPGGIPPGGVGTGGTSSFSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQSVSGGSGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPTPDLKATDNGLGKPDFSEASRERRPSYLPTPHRAYAEKRMLTEV", "length": 530 }, "evidence": [ { "id": "G3N1T8", "url": "https://omabrowser.org/oma/group/G3N1T8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P17658-1", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "gene_name": "KCNA6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV", "length": 529 }, "evidence": [ { "id": "G3N1T8", "url": "https://omabrowser.org/oma/group/G3N1T8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17659-1", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "gene_name": "Kcna6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSEKSLTLAAPGEVRGPEGEQQDAGEFQEAEGGGGCCSSERLVINISGLRYETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRMSPASRGSHEEEDEDEDSYAFPGSIPSGGLGTGGTSSFSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQPVSGGSGQNRQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPTPDLKATDNGLGKPDFAEASRERRSSYLPTPHRAYAEKRMLTEV", "length": 530 }, "evidence": [ { "id": "G3N1T8", "url": "https://omabrowser.org/oma/group/G3N1T8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61923-1", "protein_name": "Potassium voltage-gated channel subfamily A member 6", "gene_name": "Kcna6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSEKSLTLAAPGEVRGPEGEQQDAGEFQEAEGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGEEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRLSPASRSHEEEDEDEDSYAFPGSIPSGGLGTGGTSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRHEQQSVSGGSGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDVDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCGQPTPDLKATDNGLGKPDFAEASRERRPSYLPTPHRAYAEKRMLTEV", "length": 529 }, "evidence": [ { "id": "G3N1T8", "url": "https://omabrowser.org/oma/group/G3N1T8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "delayed rectifier potassium channel activity", "id": "GO:0005251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005251", "evidence": [ { "database": "UniProtKB", "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "G3N1T8", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1T8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 528, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1T8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1T8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T8" }, { "id": "SM00225", "database": "SMART", "url": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377565", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N1W8", "url": "https://www.uniprot.org/uniprotkb/G3N1W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1W8-1", "url": "https://www.uniprot.org/uniprotkb/G3N1W8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPHNHSSLAEFVLLGFPRVGHIRGWLFVLLLLAYLFTICGNMLIFLVIRLDAALHTPMYNFVSILSFLELWYTATTIPKMLANLLSDKKTISFSGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPAVMTPMLCVKMAAGCWTCGFLCPISEVILVSQLPFCSYNEIQHIFCDFPPLLSLACKDTSTNVLVDFAINAFIILITFLFIMVSYGRIMGTILQIKTIAGRKKAFSTCASHLIVVLIFFGSIIFMYVRLKESYSLTLDRTLAVVYSVLTPLVNPIIYSLRNKELIKAIKRTIFRKGERASPTQH", "length": 317, "header": "tr|G3N1W8-1|G3N1W8_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR6N2 PE=3 SV=2 CANONICAL=G3N1W8-1" }, "isoforms": [ { "isoform_ac": "G3N1W8-1", "url": "https://www.uniprot.org/uniprotkb/G3N1W8/entry", "sequence": { "sequence": "MEPHNHSSLAEFVLLGFPRVGHIRGWLFVLLLLAYLFTICGNMLIFLVIRLDAALHTPMYNFVSILSFLELWYTATTIPKMLANLLSDKKTISFSGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPAVMTPMLCVKMAAGCWTCGFLCPISEVILVSQLPFCSYNEIQHIFCDFPPLLSLACKDTSTNVLVDFAINAFIILITFLFIMVSYGRIMGTILQIKTIAGRKKAFSTCASHLIVVLIFFGSIIFMYVRLKESYSLTLDRTLAVVYSVLTPLVNPIIYSLRNKELIKAIKRTIFRKGERASPTQH", "length": 317, "header": "tr|G3N1W8-1|G3N1W8_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR6N2 PE=3 SV=2 CANONICAL=G3N1W8-1" }, "locus": { "chromosome": "3", "start_pos": 10888264, "end_pos": 10887314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003107.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003107.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055872.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055872.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:790121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790121", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QWK8-1", "protein_name": "Olfactory receptor", "gene_name": "OR6N2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPYNLSSLAEFVLLGFPKVGHVRGWLFVLLLLAYLFTICGNMLIFLVIRLDAALHTPMYHFVSILSFLELWYTATTIPKMLANLLSDKKTISFSGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPAIMTSALCAKMAAGCWTCGFLCPISEVILISQLPFCGYNEIQHIFCDFPPLLSLACKDTSINVLVDFAINAFIILITFLFIMVSYGRIIGAVLKIKTTAGRKKAFSTCASHLSVVLIFFGSIIFMYVRLKKSYSLTLDQTLAVVYSVLTPLINPIIYSLRNKELIKAIRRTIFQKGERASPTHH", "length": 317 }, "evidence": [ { "id": "G3N1W8", "url": "https://omabrowser.org/oma/group/G3N1W8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9Q5F1-1", "protein_name": "Olfactory receptor", "gene_name": "Or6n2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQHNFSSLTEFVLLGFPNVEHIRSCLFVLLLLVYLFTIGGNMLIFLVIRLDAALHKPMYHFVSVLSFLELWYTATTIPKMLANLLSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPSIMTTALCVKMAAGCWTCGFLCPISEVILVSQLPFCNYNEIPHIFCDFPPLLSLACKDTSTNVLVDFAVNAFIILITFLFIMASYGRIIGAVLKIKTAAGRRKAFSTCASHLIVVLIFFGSIIFMYVRLKKSYSLTLDRTLAVVYSVLTPLANPIIYSLRNKELIQAIKRTFFKKVEKASPTHH", "length": 317 }, "evidence": [ { "id": "G3N1W8", "url": "https://omabrowser.org/oma/group/G3N1W8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3H814-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100751255", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDQHNFSSLSEFVLLGFPNVGHIRGCLFVLLLLAYLFTIGGNMLIFLVIRLDSALHKPMYHFVSVLSFLELWYTATTIPKMLANLLSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPSIMTTSLCAKMAAGCWTCGFLCPISEVILVSQLPFCNYNEIPHIFCDFPPLLSLACKDTSTNVLVDFAVNAFIILITFLFIMTSYGRIIGAVLKIKTAAGRRKAFSTCASHLIVVLIFFGSIIFMYVRLKKSYSLTLDRTLAVVYSVLTPLANPIIYSLRNKELIQAIKRTIFKKGEKASPTHH", "length": 317 }, "evidence": [ { "id": "G3N1W8", "url": "https://omabrowser.org/oma/group/G3N1W8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8NGY6-1", "protein_name": "Olfactory receptor 6N2", "gene_name": "OR6N2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQYNHSSLAEFVFLGFASVGYVRGWLFVLLLLAYLFTICGNMLIFSVIRLDAALHTPMYHFVSVLSFLELWYTATTIPKMLSNILSEKKTISFAGCLLQTYFFHSLGASECYLLTAMAYDRYLAICRPLHYPIIMTTTLCAKMAAACWTCGFLCPISEVILASQLPFCAYNEIQHIFCDFPPLLSLACKDTSANILVDFAINAFIILITFFFIMISYARIIGAVLKIKTASGRKKAFSTCASHLAVVLIFFGSIIFMYVRLKKSYSLTLDRTLAIVYSVLTPMVNPIIYSLRNKEIIKAIKRTIFQKGDKASLAHL", "length": 317 }, "evidence": [ { "id": "G3N1W8", "url": "https://omabrowser.org/oma/group/G3N1W8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N1W8", "url": "https://www.uniprot.org/uniprotkb/G3N1W8" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N1W8", "url": "https://www.uniprot.org/uniprotkb/G3N1W8" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "G3N1W8", "url": "https://www.uniprot.org/uniprotkb/G3N1W8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N1W8", "url": "https://www.uniprot.org/uniprotkb/G3N1W8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N1W8", "url": "https://www.uniprot.org/uniprotkb/G3N1W8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G3N1W8", "url": "https://www.uniprot.org/uniprotkb/G3N1W8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1W8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1W8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1W8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1W8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1X6-1", "uniprot_ac": "G3N1X6", "uniprot_id": "G3N1X6_BOVIN", "mass": { "chemical_mass": 61383.0, "monoisotopic_mass": 61383.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Zinc finger protein 768", "type": "recommended", "evidence": [ { "id": "G3N1X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1X6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds to mammalian-wide interspersed repeat (MIRs) sequences in euchromatin and promoter regions of genes at the consensus sequence 5'-GCTGTGTG-[N20]-CCTCTCTG-3', consisting of two anchor regions connected by a linker region; the linker region probably does not contribute to the binding specificity. Required for cell homeostasis. May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "G3N1X6", "url": "https://www.uniprot.org/uniprotkb/G3N1X6#function" }, { "database": "UniProtKB", "id": "ARBA00054040", "url": "https://www.uniprot.org/uniprotkb/ARBA00054040#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1X6", "url": "https://www.uniprot.org/uniprotkb/G3N1X6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3N1X6", "locus": {} } ], "crossref": [ { "id": "G3N1X6", "url": "https://alphafold.ebi.ac.uk/entry/G3N1X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045531", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045531", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "REKTSWN", "url": "https://omabrowser.org/oma/group/REKTSWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N1X6", "url": "https://www.uniprot.org/uniprotkb/G3N1X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1X6-1", "url": "https://www.uniprot.org/uniprotkb/G3N1X6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DHREKTSWNFPEVLCAHQSPDEMGSPEGSLKGNMSENDEEEISQQEGTGDYEVEEIAFGLEPQSPGFGPQSPEFEPQSPRFEPESPGFESRSPGFVPPSPEFAPRSPESDSQSPDFEPQSPRYEPQSPGYEPKSPGYEPRSPGYEPKSPGYEPRSPGYESQSPRYGTQSPEYEPQNPEFKTQSPEFEAESSKFQEGAEMLLNPEEKNPLSIPLGVHPLDAFTQGFGEQPAGGMPLGPPFEMPTGALLAPPQFEMLQNPLGLTGTLRGPGRRGGRARGGQGPRPNICGICGKSFGRGSTLIQHQRIHTGEKPYKCEVCSKAFSQSSDLIKHQRTHTGERPYKCPRCGKAFRTHSGQKPYKCPHCGKAFGDSSYLLRHQRTHSHERPYSCPECGKCYSQNSSLRSHQRVHNGQRPFSCGICGKSFSQRSALIPHARSHAREKPFKCPECGKRFGQSSVLAIHARTHLPGRTYSCPDCGKTFNRSSTLIQHQRSHTGERPYRCAVCGKGFCRSSTLLQHHRVHSGERPYKCDDCGKAFSQSSDLIRHQRTHAAGRR", "length": 553, "header": "tr|G3N1X6-1|G3N1X6_BOVIN Isoform 1 of Zinc finger protein 768 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3N1X6-1" }, "isoforms": [ { "isoform_ac": "G3N1X6-1", "url": "https://www.uniprot.org/uniprotkb/G3N1X6/entry", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376724" }, "gene_names": [ { "name": "OR1B1", "type": "recommended", "evidence": [ { "id": "G3N1Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5" } ] }, { "name": "OR1B1", "type": "synonym", "evidence": [ { "id": "NP_001376724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376724" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3N1Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1B1", "type": "synonym", "evidence": [ { "id": "NP_001376724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376724" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376724", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376724" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N1Z5", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1Z5", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1B1", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5", "locus": { "chromosome": "11", "start_pos": 93760983, "end_pos": 93761936, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045528", "url": "https://www.ensembl.org/id/ENSBTAG00000045528" } ] } } ], "crossref": [ { "id": "G3N1Z5", "url": "https://alphafold.ebi.ac.uk/entry/G3N1Z5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045528", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045528", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507745", "url": "https://www.ncbi.nlm.nih.gov/gene/507745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507745", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507745", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELAIFFE", "url": "https://omabrowser.org/oma/group/ELAIFFE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N1Z5", "url": "https://www.orthodb.org/?gene=G3N1Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376724", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376724", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N1Z5", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1Z5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCAPNASHSPVFLLLMFSGAEVPPIVLFVLFLAIYLTTMMGNVTLVLLISRDSRLHSPMYYLLRGLSVIDMGLSTVILPQLLAHLVTHDPAIPVARCLAQLFFFYVFGVTDTLVISVMALDRYMAICDPLHYHSVMNRQCCARLLAFCWVVSVVHTMLHVGLLLPLSWAADAEGNVRLLHFFCDHRPLLQASCSDIHPNELAIFLEGGFLMMGPCALIVLSYIRIGATILRLPSAAGRHRAVSTCGSHLTMVGFFYGTIIWVYFQPPSQNSQDQDMVAAVMYTSITPLANPFVYSLRNKDVKSAFHRLLRGERVAS", "length": 317, "header": "tr|G3N1Z5-1|G3N1Z5_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1B1 PE=3 SV=2 CANONICAL=G3N1Z5-1" }, "isoforms": [ { "isoform_ac": "G3N1Z5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5/entry", "sequence": { "sequence": "MGCAPNASHSPVFLLLMFSGAEVPPIVLFVLFLAIYLTTMMGNVTLVLLISRDSRLHSPMYYLLRGLSVIDMGLSTVILPQLLAHLVTHDPAIPVARCLAQLFFFYVFGVTDTLVISVMALDRYMAICDPLHYHSVMNRQCCARLLAFCWVVSVVHTMLHVGLLLPLSWAADAEGNVRLLHFFCDHRPLLQASCSDIHPNELAIFLEGGFLMMGPCALIVLSYIRIGATILRLPSAAGRHRAVSTCGSHLTMVGFFYGTIIWVYFQPPSQNSQDQDMVAAVMYTSITPLANPFVYSLRNKDVKSAFHRLLRGERVAS", "length": 317, "header": "tr|G3N1Z5-1|G3N1Z5_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1B1 PE=3 SV=2 CANONICAL=G3N1Z5-1" }, "locus": { "chromosome": "11", "start_pos": 93761936, "end_pos": 93760986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063032.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063032.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055900.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055900.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507745", "name": "", "url": 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"MSCAPNASHSPIFLLLGFSRAGVPHTFLFLLFLFIYLTTILGNVTLVLLISWDSRLHSPMYYLLRGLSMIDLGLSTVTLPQLLVHLSSDSPAIPAARCLTQFFFFYAFGVTDTLVIAVMALDRYVAICDPLHYALVMNRQICARLLALSWVVSIVHTMLHVGLILPLCWAGDAGGNVKLPHFFCDHRPLLRASCSDTHSNELAIFLEGGFLMLGPCSLIVLSYARIGITILRLPSAAGRRRAVSTCGSHLTMVGFLYGTIIWVYFQPPSQNSRNQDMVASVMYTAITPLANPFVYSLRNKDVKGALHRLLRQGRVDS", "length": 317 }, "evidence": [ { "id": "G3N1Z5", "url": "https://omabrowser.org/oma/group/G3N1Z5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N1Z5", "url": "https://www.uniprot.org/uniprotkb/G3N1Z5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", 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"database": "UniProtKB", "id": "G3N1Z8", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8#function" }, { "database": "UniProtKB", "id": "ARBA00035627", "url": "https://www.uniprot.org/uniprotkb/ARBA00035627#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1Z8", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR152", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8", "locus": { "chromosome": "29", "start_pos": 45340103, "end_pos": 45341464, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046728", "url": "https://www.ensembl.org/id/ENSBTAG00000046728" } ] } } ], "crossref": [ { "id": "G3N1Z8", "url": "https://alphafold.ebi.ac.uk/entry/G3N1Z8", "database": "AlphaFoldDB", 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"IDTAMEASLGAPGRWPRTELDDEDYPQGGWDTVFLVALLLLGLPANGLMAWLAGSQARQGAGTRLALLLLSLALSDFLFLAAAAFQIMEIQHGGHWPLGTAACRFYYFLWGVSYSSGLFLLATLSLDRCLLALCPRWYPERRPARLPLWVCAGVWVLATLFSVPWLVFPEAAVWWYDLVICLDFWDSEELPLRMLEILGGFLPFLVLVVCHVLTQAAACRPCRRQPGAPACRGFARVAKTILSAYVVLRLPYQLAQLLYLAFLWDFYPGYLLWEALVYSDYLILLNSCLSPFLCLLASTDLRALLRAMLASFAAALCEERPGSFMPADPQTQVDSGDQTVPGPVAEAEPQVNPTAQPQVNPEAKQQVNPAAQPQEDDEGPPQPDSGAQSQASPKAQPPGPTTSSAPSACEEASSTPAMDSTLEAPMNPATPAASEGEGPSGAPREEAPGAGPT", "length": 453, "header": "tr|G3N1Z8-1|G3N1Z8_BOVIN Isoform 1 of Probable G-protein coupled receptor 152 OS=Bos taurus OX=9913 GN=GPR152 PE=4 SV=3 CANONICAL=G3N1Z8-1" }, "isoforms": [ { "isoform_ac": "G3N1Z8-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8/entry", "sequence": { "sequence": "IDTAMEASLGAPGRWPRTELDDEDYPQGGWDTVFLVALLLLGLPANGLMAWLAGSQARQGAGTRLALLLLSLALSDFLFLAAAAFQIMEIQHGGHWPLGTAACRFYYFLWGVSYSSGLFLLATLSLDRCLLALCPRWYPERRPARLPLWVCAGVWVLATLFSVPWLVFPEAAVWWYDLVICLDFWDSEELPLRMLEILGGFLPFLVLVVCHVLTQAAACRPCRRQPGAPACRGFARVAKTILSAYVVLRLPYQLAQLLYLAFLWDFYPGYLLWEALVYSDYLILLNSCLSPFLCLLASTDLRALLRAMLASFAAALCEERPGSFMPADPQTQVDSGDQTVPGPVAEAEPQVNPTAQPQVNPEAKQQVNPAAQPQEDDEGPPQPDSGAQSQASPKAQPPGPTTSSAPSACEEASSTPAMDSTLEAPMNPATPAASEGEGPSGAPREEAPGAGPT", "length": 453, "header": "tr|G3N1Z8-1|G3N1Z8_BOVIN Isoform 1 of Probable G-protein coupled receptor 152 OS=Bos taurus OX=9913 GN=GPR152 PE=4 SV=3 CANONICAL=G3N1Z8-1" }, "locus": { "chromosome": "29", "start_pos": 45341464, "end_pos": 45340106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066318.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066318.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055903.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055903.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 453, "start_aa": "Thr", "end_pos": 453, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr453", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N1Z8", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3N1Z8", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N1Z8", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "G3N1Z8", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1Z8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 453, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1Z8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1Z8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Z8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 294, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 401, 453 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N203-1", "uniprot_ac": "G3N203", "uniprot_id": "G3N203_BOVIN", "mass": { "chemical_mass": 58095.0, "monoisotopic_mass": 58095.0 }, "refseq": { "ac": "NP_001193447", "name": "cytidine and dCMP deaminase domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193447" }, "gene_names": [ { "name": "CDADC1", "type": "recommended", "evidence": [ { "id": "G3N203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ] }, { "name": "CDADC1", "type": "synonym", "evidence": [ { "id": "NP_001193447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193447" } ] } ], "protein_names": [ { "name": "Cytidine and dCMP deaminase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "G3N203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N203/entry#names_and_taxonomy" } ] }, { "name": "3.5.4.5", "type": "synonym", "evidence": [ { "id": "G3N203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N203/entry#names_and_taxonomy" } ] }, { "name": "Cytidine deaminase", "type": "synonym", "evidence": [ { "id": "G3N203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N203/entry#names_and_taxonomy" } ] }, { "name": "cytidine and dCMP deaminase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001193447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193447" } ] } ], "function": [ { "annotation": "Catalyzes the deamination of cytidine and deoxycytidine into uridine and deoxyuridine, respectively. May play an important role in testicular development and spermatogenesis.", "evidence": [ { "database": "UniProtKB", "id": "G5E525", "url": "https://www.uniprot.org/uniprotkb/G5E525#function" }, { "database": "UniProtKB", "id": "ARBA00056832", "url": "https://www.uniprot.org/uniprotkb/ARBA00056832#function" }, { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDADC1", "url": "https://www.uniprot.org/uniprotkb/G3N203", "locus": { "chromosome": "12", "start_pos": 18895609, "end_pos": 18867135, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002271", "url": "https://www.ensembl.org/id/ENSBTAG00000002271" } ] } } ], "crossref": [ { "id": "G3N203", "url": "https://alphafold.ebi.ac.uk/entry/G3N203", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002271", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002271", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512184", "url": "https://www.ncbi.nlm.nih.gov/gene/512184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016193", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016193", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512184", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512184", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITHIYTT", "url": "https://omabrowser.org/oma/group/ITHIYTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N203", "url": "https://www.orthodb.org/?gene=G3N203", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E525", "url": "https://www.orthodb.org/?gene=G5E525", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11086:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11086:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13433", "url": "https://www.rhea-db.org/rhea/13433", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16069", "url": "https://www.rhea-db.org/rhea/16069", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N203-1", "url": "https://www.uniprot.org/uniprotkb/G3N203-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E525", "url": "https://www.uniprot.org/uniprotkb/G5E525", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E525-1", "url": "https://www.uniprot.org/uniprotkb/G5E525-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREAGQMQNLESAGAGRSVSTQTGSMTGEIPRLSKVNLFTLLSLWMELFPAVKTQRQKSQEKEEGKHGPLGDNEEMARVSADKKQVKRTGLVVVKNMKIVGLHCSSEDLHAGKIALIKHGSKLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEISLLTEASGFEDAKLDAKAVERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKISKTLPDTNFDFYSECKQERIKEYEMIFLVSNEEMHKQILMTIGLENLCENPYFSNLRQNMKDLVLLLAAVASSVPNFKHYGFYCGNTEHSNEIHNQSLPQEIARHCMIQARLLAYRTEDHKTGVGAVIWAEGKSRSCDGTGAMYFIGCGYNAFPVGSEYADFPHMDDKQKDREIRKFRYIVHAEQNALTFRCQEIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMRFGEVEGVSKFTWQLNPSRTGVLEQNEPESRENGVLGSVALDEEPHQNKKLRLANH", "length": 515, "header": "tr|G3N203-1|G3N203_BOVIN Isoform 1 of Cytidine and dCMP deaminase domain-containing protein 1 OS=Bos taurus OX=9913 GN=CDADC1 PE=3 SV=2 CANONICAL=G3N203-1" }, "isoforms": [ { "isoform_ac": "G3N203-1", "url": "https://www.uniprot.org/uniprotkb/G3N203/entry", "sequence": { "sequence": "MREAGQMQNLESAGAGRSVSTQTGSMTGEIPRLSKVNLFTLLSLWMELFPAVKTQRQKSQEKEEGKHGPLGDNEEMARVSADKKQVKRTGLVVVKNMKIVGLHCSSEDLHAGKIALIKHGSKLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEISLLTEASGFEDAKLDAKAVERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKISKTLPDTNFDFYSECKQERIKEYEMIFLVSNEEMHKQILMTIGLENLCENPYFSNLRQNMKDLVLLLAAVASSVPNFKHYGFYCGNTEHSNEIHNQSLPQEIARHCMIQARLLAYRTEDHKTGVGAVIWAEGKSRSCDGTGAMYFIGCGYNAFPVGSEYADFPHMDDKQKDREIRKFRYIVHAEQNALTFRCQEIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMRFGEVEGVSKFTWQLNPSRTGVLEQNEPESRENGVLGSVALDEEPHQNKKLRLANH", "length": 515, "header": "tr|G3N203-1|G3N203_BOVIN Isoform 1 of Cytidine and dCMP deaminase domain-containing protein 1 OS=Bos taurus OX=9913 GN=CDADC1 PE=3 SV=2 CANONICAL=G3N203-1" }, "locus": { "chromosome": "12", "start_pos": 18895160, "end_pos": 18867334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063579.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063579.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055908.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055908.2" } ] } }, { "isoform_ac": "G5E525-1", "url": "https://www.uniprot.org/uniprotkb/G5E525/entry", "sequence": { "sequence": "MREAGQMQNLESAGAGRSVSTQTGSMTGEIPRLSKVNLFTLLSLWMELFPAVKTQRQKSQVKRTGLVVVKNMKIVGLHCSSEDLHAGKIALIKHGSKLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEISLLTEASGFEDAKLDAKAVERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKISKTLPDTNFDFYSECKQERIKEYEMIFLVSNEEMHKQILMTIGLENLCENPYFSNLRQNMKDLVLLLAAVASSVPNFKHYGFYCGNTEHSNEIHNQSLPQEIARHCMIQARLLAYRTEDHKTGVGAVIWAEGKSRSCDGTGAMYFIGCGYNAFPVGSEYADFPHMDDKQKDREIRKFRYIVHAEQNALTFRCQEIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMRFGEVEGVSKFTWQLNPSRTGVLEQNEPESRENGVLGSVALDEEPHQNKKLRLANH", "length": 490, "header": "tr|G5E525-1|G3N203_BOVIN Computationally mapped isoform of Cytidine and dCMP deaminase domain-containing protein 1 OS=Bos taurus OX=9913 GN=CDADC1 PE=3 SV=2 CANONICAL=G3N203-1" }, "locus": { "chromosome": "12", "start_pos": 18895160, "end_pos": 18867334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002932.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002932.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002932.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002932.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:512184", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512184", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NZE1-1", "protein_name": "Cytidine and dCMP deaminase domain-containing protein 1", "gene_name": "CDADC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHGADEEEEATAAVRGPRVSVASTQTDSMAGQIPRLSKVNLFTLFSLWMELFPSTEQRKKSQVKKSGLVVVKNMTIIGLHCSSTDLHAGQIALIKHGSKLKNCDLYFSRKPCSTCLKMIVNAGVNRISYWPADPEISLQNEASNPVTTGDAKLDAKAVERLKSNSRARVCVLLQPLVCYMVQFIEETSTKLDFIQKIAKSQPDFNTDFYTACRQERIKEYESLFLISNEETHKQILMTIGLENLCENPYFSNLRQNMKDLVLVLATVAASVPVFGCFGFYSSEPQPTNETCHQGLPQEIARHCMVQARLLAYRTEDHKTGVGAIIWAEEKSRGCDGTGAMYFVGCGYNAFPVGSEYADFPHMDDKQKDREIRKFRYIIHAEQNALTFRCREIKPDERSMIFVTKCPCDECVPLIKGAGIKQIYAGDIDAGKKKADISYMKFGELEGVSKFTWQLNPCHPNAVEFHDPTMRENGVQKTKSIDDQQHQHKKLCLGHY", "length": 495 }, "evidence": [ { "id": "G3N203", "url": "https://omabrowser.org/oma/group/G3N203/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8I6A0N0-1", "protein_name": "Cytidine and dCMP deaminase domain-containing protein 1", "gene_name": "Cdadc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKETDPMQSLEGSGAERSVGTQTGSMTGQIPRLSKVNLFTLLSLWMELFPGVEAQGQKSQKTEEETRGPLGDNEDLARVSTDKKQVKKTGLVVVKNMKIIGLHCSSEDLHTGQIALIKHGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPSDPEISLLTEASSSEDAKLDAKAAERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKTAKALPGADTDFYSECKQERIKEYEMLFLVSNEEMHKQILMTIGLENLCENPYFSNLRQNMKDLILLLATVASSVPNLKHFGFYCSNPEQINEIHNQSLPQEVARHCMVQARLLAYRTEDHKTGVGAVIWAEAKSRSCDGTGAMYFVGCGYNAFPVGSEYADFPHMDDKHKDREIRKFRYIIHAEQNALTFRCQDIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMKFGELEGVHKFTWQLNPSEAYSLDPDEPERRENGVLRRRSAKEEQRSNKRPRLETRSAGSTTAACF", "length": 525 }, "evidence": [ { "id": "G3N203", "url": "https://omabrowser.org/oma/group/G3N203/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H8S5-1", "protein_name": "Cytidine and dCMP deaminase domain-containing protein 1", "gene_name": "Cdadc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKEADQMQSVEGSGAGRSVGTQTGSMTGQIPRLSKVNLFTLLSLWMELFPGVEAQGQKSQKNEEENRGPLGDNEELARVSDKKQVKKTGLVVVKNMKIIGLHCSSEDLHTGQIALIKHGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPSDPEISLLTEASSSEDAKLDAKAAERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKTAKALSGADTDFYSECKQERIKEYEMLFLVSNEEMHKQILMTIGLENLCENPYFSDLRQNMKDLILLLATVASSVPSLKHFGFYCSNPEQINEIHHQSLPQEVARHCMVQARLLAYRTEDHKTGVGAVIWAEGKSRSCDGTGAMYFIGCGYNAFPVGSEYADFPHMDDKHKDREIRKFRYIIHAEQNALTFRCQDIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMKFGELEGVRKFTWQLNPSEAYSLDQNEPERRENGVLRRRSTKEEQHSSKRPRLETHSAGRATVQ", "length": 522 }, "evidence": [ { "id": "G3N203", "url": "https://omabrowser.org/oma/group/G3N203/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5U3U4-1", "protein_name": "dCTP deaminase", "gene_name": "cdadc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESNSWRSHRESDGNRSIPNGDDARNVRETGVQTDAKVQGQGPRLSKANLFTLLSLWMELFPKREACQQENDAAGVSGLVVVHECRVLGLHCSSAQLHAGQVAVVKHGPRLKSCELYFSRKPCSTCLKMLINAGVSRISYWPGDAELSLLSESLHHGSSSALQEAVLDATAAERLKSNSRPHISVLLQPLDCTVLQFLDETSQNADFLGKIVADNPALDTGDIYRREFWNNSDNFLEKFFISDEERHKYVLNKMGLENFCMEPNFSNLRQHMRNLIRILASVASSVPALLEDYGFFMREPVGMGSPGLPQGVIRHCVIQARLLACRTEDPKVGVGAVIWAEGKQSQCDGTGQLYLVGCGYNAYPVGSQYAEYPQMDHKQEERQNRKYRYILHAEQNALTFRSAEIKAEDNTMMFVTKCPCDECVPLIGCAGIKQIYTTDLDSNKVKHDISYLRFNKLNGVQKFIVSVREK", "length": 471 }, "evidence": [ { "id": "G3N203", "url": "https://omabrowser.org/oma/group/G3N203/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BMD5-1", "protein_name": "dCTP deaminase", "gene_name": "Cdadc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKETDQMQSLEGSGAERSVGTQTGSMTGQIPRLSKVNLFTLLSLWMELFPGVEAQGQKSQKTEEESRGPLGDNEELTRVSTEKKQVKKTGLVVVKNMKIIGLHCSSEDLHTGQIALIKHGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPSDPEISLLTEASSSEDAKLDAKAAERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKTAKALPGADTDFYSECKQERIKEYEMLFLVSNEERHKQILMTIGLESLCEDPYFSNLRQNMKDLILLLATVASSVPNLKHFGFYCSSPEQINEIHNQSLPQEVARHCMVQARLLAYRTEDHKTGVGAVIWAEAKSRSCDGTGAMYFIGCGYNAFPVGSEYADFPHMDDKHKDREIRKFRYIIHAEQNALTFRCQDIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMKFGELEGVRKFTWQLNPSEAYSLDPNEPERRENGVLRRRSAKDEQRSSKRPRLETRSAGRATLQ", "length": 523 }, "evidence": [ { "id": "G3N203", "url": "https://omabrowser.org/oma/group/G3N203/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWV3-1", "protein_name": "dCTP deaminase", "gene_name": "CDADC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEAGQMQNLESARAGRSVSTQTGSMTGQIPRLSKVNLFTLLSLWMELFPAEAQRQKSQKNEEGKHGPLGDNEERTRVSTDKRQVKRTGLVVVKNMKIVGLHCSSEDLHAGQIALIKHGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEISLLTEASSSEDAKLDAKAVERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKITKTLPDANTDFYYECKQERIKEYEMLFLVSNEEMHKQILMTIGLENLCENPYFSNLRQNMKDLILLLATVASSVPNFKHFGFYRSNPEQINEIHNQSLPQEIARHCMVQARLLAYRTEDHKTGVGAVIWAEGKSRSCDGTGAMYFVGCGYNAFPVGSEYADFPHMDDKQKDREIRKFRYIIHAEQNALTFRCQEIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMRFGELEGVSKFTWQLNPSGAYGLEQNEPERRENGVLRPVPQKEEQHQDKKLRLGIH", "length": 514 }, "evidence": [ { "id": "G3N203", "url": "https://omabrowser.org/oma/group/G3N203/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "importin-alpha family protein binding", "id": "GO:0061676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061676", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" }, { "name": "cytidine deaminase activity", "id": "GO:0004126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004126", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" }, { "name": "dCMP deaminase activity", "id": "GO:0004132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004132", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA cytosine deamination", "id": "GO:0070383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070383", "evidence": [ { "database": "UniProtKB", "id": "G3N203", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13433", "name": "", "equation": "2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TAP6-1", "G3N203-1" ], "evidence": [ { "id": "13433", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13433" } ] }, { "id": "16069", "name": "", "equation": "cytidine + H2O + H(+) = uridine + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TAP6-1", "G3N203-1" ], "evidence": [ { "id": "16069", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16069" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9TAP6", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0AAA9TAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAP6" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0AAA9TAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAP6" } ] } ] }, { "uniprot_ac": "G3N203", "gene_name": "CDADC1", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "G3N203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "G3N203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N203" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N203-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 515, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N203-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N203" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N203", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N203" }, { "id": "PS51747", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51747" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CMP/dCMP-type deaminase", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 169, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.4.5", "ec_name": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "3.5.4.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.5" }, { "id": "3.5.4.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.4.5" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N206-1", "uniprot_ac": "G3N206", "uniprot_id": "G3N206_BOVIN", "mass": { "chemical_mass": 14858.0, "monoisotopic_mass": 14858.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Small ribosomal subunit protein uS8", "type": "recommended", "evidence": [ { "id": "G3N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N206/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S15a", "type": "synonym", "evidence": [ { "id": "G3N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N206/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N206", "url": "https://www.uniprot.org/uniprotkb/G3N206" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3N206", "locus": {} } ], "crossref": [ { "id": "G3N206", "url": "https://alphafold.ebi.ac.uk/entry/G3N206", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046952", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046952", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RIFFRTH", "url": "https://omabrowser.org/oma/group/RIFFRTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N206", "url": "https://www.uniprot.org/uniprotkb/G3N206", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N206-1", "url": "https://www.uniprot.org/uniprotkb/G3N206-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLHPSHQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", 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"tr|G3N212-1|G3N212_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN=OR1J4 PE=3 SV=1 CANONICAL=G3N212-1" }, "locus": { "chromosome": "11", "start_pos": 93665286, "end_pos": 93664348, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063155.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063155.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055917.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZJM3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRMENQSSVSKFFLRGLPIPPEQQGVFFALFLGMYLTTVLGNLLIILLIRLDPHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSISYAGCITQTYFFLFFICLDDFLLTSMAYDRYVAICHPLHYTTIMRGGLCTLLVTVSWILSCAVALCHTLLLAQLSFCAHNIIPHYFCDLGALLKLSCSDTSVNELVIFTVGLAVITLPLMCILVSYGCIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFVPSSSTSSDKDIVASVMYTVVTPLLNPFIYSLRNRDMKGALGKLFHKAEVLSQ", "length": 313 }, "evidence": [ { "id": "G3N212", "url": "https://omabrowser.org/oma/group/G3N212/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N212", "url": "https://www.uniprot.org/uniprotkb/G3N212" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N212", "url": "https://www.uniprot.org/uniprotkb/G3N212" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N212", "url": "https://www.uniprot.org/uniprotkb/G3N212" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3N212", "url": "https://www.uniprot.org/uniprotkb/G3N212" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N212-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N212-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N212" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N212", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N212" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N226-1", "uniprot_ac": "G3N226", "uniprot_id": "G3N226_BOVIN", "mass": { "chemical_mass": 35152.0, "monoisotopic_mass": 35152.0 }, "refseq": { "ac": "NP_001377577", "name": "olfactory receptor family 4 subfamily G member 18", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377577" }, "gene_names": [ { "name": "OR4G18", "type": "recommended", "evidence": [ { "id": "G3N226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N226" } ] }, { "name": "OR4G18", "type": "synonym", "evidence": [ { "id": "NP_001377577", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377577" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3N226", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N226/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily G member 18", "type": "synonym", "evidence": [ { "id": "NP_001377577", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377577" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377577", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377577" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N226", "url": "https://www.uniprot.org/uniprotkb/G3N226#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N226", "url": "https://www.uniprot.org/uniprotkb/G3N226" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4G18", "url": "https://www.uniprot.org/uniprotkb/G3N226", "locus": { "chromosome": "10", "start_pos": 27658123, "end_pos": 27657191, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046009", "url": "https://www.ensembl.org/id/ENSBTAG00000046009" } ] } } ], "crossref": [ { "id": "G3N226", "url": "https://alphafold.ebi.ac.uk/entry/G3N226", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100140382", "url": "https://www.ncbi.nlm.nih.gov/gene/100140382", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100140382", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140382", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLNIMNS", "url": "https://omabrowser.org/oma/group/YLNIMNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N226", "url": "https://www.orthodb.org/?gene=G3N226", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377577", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377577", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N226", "url": "https://www.uniprot.org/uniprotkb/G3N226", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N226-1", "url": "https://www.uniprot.org/uniprotkb/G3N226-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGPNDSVVSEFVLLGLSGSYETKVFLTLIFSWIYLGIILGNLFILLLVIFNSHLHSPMYFLLANLSFIDMGVASTTVPKMITDLLNEYKIISFQGCMVQICFIHIMGGVEMVLLIAMAFDRYTAICKPLYYLNIMNPKICVSFVITGWVIGVTHAMSQFAFIINLPFCGPNKVDSFYCDFPRIIKLACTDGAKFEFIVAANSGFMSMGTFFLLILSYIFILVTVWKRSSGDLSKAFVTLSAHITVVVLFFTPCMFLYVWPFPRSSIDKYLFIADFALTPVLNPIIYTLRNKEIKVAIKRLIKRHYVKFC", "length": 310, "header": "tr|G3N226-1|G3N226_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4G18 PE=3 SV=2 CANONICAL=G3N226-1" }, "isoforms": [ { "isoform_ac": "G3N226-1", "url": "https://www.uniprot.org/uniprotkb/G3N226/entry", "sequence": { "sequence": "MDGPNDSVVSEFVLLGLSGSYETKVFLTLIFSWIYLGIILGNLFILLLVIFNSHLHSPMYFLLANLSFIDMGVASTTVPKMITDLLNEYKIISFQGCMVQICFIHIMGGVEMVLLIAMAFDRYTAICKPLYYLNIMNPKICVSFVITGWVIGVTHAMSQFAFIINLPFCGPNKVDSFYCDFPRIIKLACTDGAKFEFIVAANSGFMSMGTFFLLILSYIFILVTVWKRSSGDLSKAFVTLSAHITVVVLFFTPCMFLYVWPFPRSSIDKYLFIADFALTPVLNPIIYTLRNKEIKVAIKRLIKRHYVKFC", "length": 310, "header": "tr|G3N226-1|G3N226_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4G18 PE=3 SV=2 CANONICAL=G3N226-1" }, "locus": { "chromosome": "10", "start_pos": 27658120, "end_pos": 27657191, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065343.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065343.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055931.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055931.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100140382", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140382", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LS44-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100755034", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPMDQLNHSTVSEFVLLGLSSSWETKVFLMLTFSMLYLGIILGNLFIVILVMADSHLHSPMYFLLANLSLNDVWVSSTTVPKMISDLLKERKVISFHSCMTQICFIHIMGGVEMVLLIAMAFDRYTAICKPLRYLSIMSPKICISFVIAGWVTGVIHALSQFSFVINLPFCGPNKVDSFYCDFPRIIQLACTDRDKFEFIIAANSGFMSMGTFFLLLLSYVFILVTVWQRSSGDLSKALVTLSAHITVVVLFFTPCMFLYVWPFPTSSTDKYLFIADFAITPALNPVIYTLRNKDIRVSIQRLYKRAGYDRYC", "length": 313 }, "evidence": [ { "id": "G3N226", "url": "https://omabrowser.org/oma/group/G3N226/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZLF7-1", "protein_name": "Olfactory receptor", "gene_name": "Or4g16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQLNASRVSEFVLLGLSSSWEMKVFLMVTFSMLYIGIILGNLFIVILVIADSHLHSPMYFLLANLSLNDVWVSSTTVPKMISDLLKEHKVISFHNCMSQICFIHIMGGVEMVLLIAMAFDRYIAICKPLRYLSIMSPRICISFVIAGWVTGVIHALSQFSFVVNLPFCGPNKVDSFYCDFPRIIQLACTDGDKFEFVVAANSGFMSMGTFFLLLLSYVFILVTVWQRSSGDLSKALVTLSAHITVVVLFFTPCMFLYVWPFPTSSIDKYLFIADFAITPALNPVIYTLRNKDIRISIQRLCKRANCSRF", "length": 310 }, "evidence": [ { "id": "G3N226", "url": "https://omabrowser.org/oma/group/G3N226/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VF38-1", "protein_name": "Olfactory receptor", "gene_name": "Or4g16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPMDQLNDSRVSEFVLLGLSSSWETKVFLMVTFSMLYIGIILGNLFIVILVIADSHLHSPMYFLLANLSLNDVWVSSTTVPKMISDLLKEHKVISFHNCMTQICFIHIMGGVEMVLLIAMAFDRYTAICKPLRYLSIMSPRICISFVIAGWVTGVVHAMSQFSFVVSLPFCGPNKVDSFYCDFPRIIQLACTDGDKFEFVVAANSGFMSMGTFFLLLLSYVFILVTVWQRSSGDLSKALVTLSAHITVVVLFFTPCMFLYVWPFPTSSIDKYLFIADFAITPALNPVIYTFRNKDIRIAIGRLSKRAVCSRFC", "length": 313 }, "evidence": [ 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"https://www.ebi.ac.uk/interpro/entry/IPR001699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100299988", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299988", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EGKCNHA", "url": "https://omabrowser.org/oma/group/EGKCNHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N243", "url": "https://www.orthodb.org/?gene=G3N243", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267:SF116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267:SF116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002700004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002700004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N243-1", "url": "https://www.uniprot.org/uniprotkb/G3N243-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSSRAHAFSVEALVGRPSKRKLQDPREETQPELLEKEGGEEEDRRSSAAAGTKSEPPEKRTKTDPLATTFGFNSFGSLEEKDIIQVELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYYVAIDVVPVDSKRYRYIYHSSQWMIAGNTDHSCITPRVYIHPDSPCSGETWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVMKQDSRVDMSRIQSLPAEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLETYPWRPSLTLDFKTFSADTQSGSSSSSPVTSSGGAPSPLNSLLSPLCSPPTFHIPTSSLGMPRPEVYLHSINLPLCYKICPNNFWQQQPLVLSALESLASNNSSQSSAPLMMEVPMLSSLGVTNSKNGSSGDLNGQCLQAPKSSNQMYELQALENILSPNPIAQEAIACSFHPSYGFYRYNFSTPPRLVNAANRLKVNDNSQVSFIEGKYNHSHWYPKISHCL", "length": 513, "header": "tr|G3N243-1|G3N243_BOVIN Isoform 1 of T-box transcription factor 22 OS=Bos taurus OX=9913 GN=TBX22 PE=4 SV=1 CANONICAL=G3N243-1" }, "isoforms": [ { "isoform_ac": "G3N243-1", "url": "https://www.uniprot.org/uniprotkb/G3N243/entry", "sequence": { "sequence": "MALSSRAHAFSVEALVGRPSKRKLQDPREETQPELLEKEGGEEEDRRSSAAAGTKSEPPEKRTKTDPLATTFGFNSFGSLEEKDIIQVELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYYVAIDVVPVDSKRYRYIYHSSQWMIAGNTDHSCITPRVYIHPDSPCSGETWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVMKQDSRVDMSRIQSLPAEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLETYPWRPSLTLDFKTFSADTQSGSSSSSPVTSSGGAPSPLNSLLSPLCSPPTFHIPTSSLGMPRPEVYLHSINLPLCYKICPNNFWQQQPLVLSALESLASNNSSQSSAPLMMEVPMLSSLGVTNSKNGSSGDLNGQCLQAPKSSNQMYELQALENILSPNPIAQEAIACSFHPSYGFYRYNFSTPPRLVNAANRLKVNDNSQVSFIEGKYNHSHWYPKISHCL", "length": 513, "header": "tr|G3N243-1|G3N243_BOVIN Isoform 1 of T-box transcription factor 22 OS=Bos taurus OX=9913 GN=TBX22 PE=4 SV=1 CANONICAL=G3N243-1" }, "locus": { "chromosome": "X", "start_pos": 72521468, "end_pos": 72511787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066313.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066313.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055948.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055948.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100299988", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299988", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUM5-1", "protein_name": "T-box transcription factor 22", "gene_name": "Tbx22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTKIPPAASSLPGMALSSRAHAFSVEALMGRPSKRKAQDPREEMQPELQEEQFIEEGEEILSSPSGDSEQPAEKRPKAESSKTVFSCSDNESNSLESLLEESIIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVVEEDSRIDLSLIQSFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGFLETYPWRPSFTMDFKPFVPDTQNGSSGSSPVTSSGGAPSPLNSLLSPSCSPPTVYIPPSSIGMTHPETYLHNVNVPFCYRICPTNYWRPQPFVLPTPERLPSFNSSQSFPPLMMEVPLVSSRGFINSNSGLHEDCNGHCLQASHSTSQMLYGLQNPGNIFHPNPIAQEAICCPFHPPNGCYRYNVSMPPRLENVANHLSENGTNQISFTGGSCDHSHWYPAINHYF", "length": 533 }, "evidence": [ { "id": "G3N243", "url": "https://omabrowser.org/oma/group/G3N243/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YGY4-1", "protein_name": "T-box 22", "gene_name": "TBX22", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALSSRAHAFSVEALVGRSAKRKGPDGRDEESGAGCRQSRRASEPEKRPKAGAESREVGDEVQVELQGSELWKRFHEIGTEMIITKAGRRMFPSVRVKVKGLEPLQQYYIAIDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRLYIHPDSPCSGETWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVIAQDSRFDLAQIQSLPAEGVRTFSFQETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGLLEPFPWRPPLALDLKAFGADSQGSSSSSSPVTSSAGTPSPLNPLLSPPCSPPTFHLAVSGVGAPCPESHLPGLGVPLCYRLCPANVLRQQPLILPSHQKPGGPGPPILPHFVVDVPKLSSLGIASLKSAKSEDLSGPCLQVPNSASQMLYGLHASGNIFPSSPIAREALNCSLHPPYGLYGYSFSMPSRLTSAASHFGVSDSLPAAFRDSRCNHPSWHSAINHCL", "length": 489 }, "evidence": [ { "id": "G3N243", "url": "https://omabrowser.org/oma/group/G3N243/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8K402-1", "protein_name": "T-box transcription factor TBX22", "gene_name": "Tbx22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALSSRAHAFSVEALMGRPSKRKAQDPREEMQPELQEEQFVEEGEEILRSPSRDSQQPEKRLKAESSKTVFSCSDESNSQESLQEESVIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYNPRVHVVEQDSRIDLSLIESFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGFLETYPWMPSFSMDFKTFVTDTQSGSSGSSPVTSSGGAPSPLNSLLSPSCSPPMVYIPPSSFGMTYPDAYLHSVNIPFCYRICPTNNWRSQPFVLPTPERLPSFIIPQTLPPLMMEVPVVSSRGIINPNSGLHEDCNGQCLQASHSANQMLYGLQNPGNIFHPNAIAQEAISYPFHPPNGCYRYTISMPPRLENVASHLSENGTSQISFTEGSCDHSHWYPAINHYL", "length": 517 }, "evidence": [ { "id": "G3N243", "url": "https://omabrowser.org/oma/group/G3N243/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y458-1", "protein_name": "T-box transcription factor TBX22", "gene_name": "TBX22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL", "length": 520 }, "evidence": [ { "id": "G3N243", "url": "https://omabrowser.org/oma/group/G3N243/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3N243", "url": "https://www.uniprot.org/uniprotkb/G3N243" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N243-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 513, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N243-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N243" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N243" }, { "id": "PS50252", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50252" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-box", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 277, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 391, "end_pos": 393 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 501, "end_pos": 503 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N250-1", "uniprot_ac": "G3N250", "uniprot_id": "G3N250_BOVIN", "mass": { "chemical_mass": 18247.0, "monoisotopic_mass": 18247.0 }, "refseq": { "ac": "NP_001192385", "name": "F-box only protein 48", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192385" }, "gene_names": [ { "name": "FBXO48", "type": "recommended", "evidence": [ { "id": "G3N250", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N250" } ] }, { "name": "FBXO48", "type": "synonym", "evidence": [ { "id": "NP_001192385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192385" } ] } ], "protein_names": [ { "name": "F-box only protein", "type": "recommended", "evidence": [ { "id": "G3N250", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N250/entry#names_and_taxonomy" } ] }, { "name": "F-box only protein 48", "type": "synonym", "evidence": [ { "id": "NP_001192385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192385" } ] } ], "function": [ { "annotation": "Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.", "evidence": [ { "database": "UniProtKB", "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250#function" }, { "database": "UniProtKB", "id": "RU369085", "url": "https://www.uniprot.org/uniprotkb/RU369085#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FBXO48", "url": "https://www.uniprot.org/uniprotkb/G3N250", "locus": { "chromosome": "11", "start_pos": 66861021, "end_pos": 66864669, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047772", "url": "https://www.ensembl.org/id/ENSBTAG00000047772" } ] } } ], "crossref": [ { "id": "G3N250", "url": "https://alphafold.ebi.ac.uk/entry/G3N250", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047772", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047772", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22113", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22113", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "786890", "url": "https://www.ncbi.nlm.nih.gov/gene/786890", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:786890", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786890", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMCPMDA", "url": "https://omabrowser.org/oma/group/IMCPMDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N250", "url": "https://www.orthodb.org/?gene=G3N250", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12874", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12874", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12874:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12874:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192385", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192385", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N250-1", "url": "https://www.uniprot.org/uniprotkb/G3N250-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKNSKRNHASRVSDIEWNSVDAEREKKECPNNFVELLPPEVTFKIFSQLDIRSLCRASVTCRSWNHAIRHSDSLWKPHCLTVRAVCQREIDDDLESGYPWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER", "length": 155, "header": "tr|G3N250-1|G3N250_BOVIN Isoform 1 of F-box only protein OS=Bos taurus OX=9913 GN=FBXO48 PE=4 SV=1 CANONICAL=G3N250-1" }, "isoforms": [ { "isoform_ac": "G3N250-1", "url": "https://www.uniprot.org/uniprotkb/G3N250/entry", "sequence": { "sequence": "MKKNSKRNHASRVSDIEWNSVDAEREKKECPNNFVELLPPEVTFKIFSQLDIRSLCRASVTCRSWNHAIRHSDSLWKPHCLTVRAVCQREIDDDLESGYPWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER", "length": 155, "header": "tr|G3N250-1|G3N250_BOVIN Isoform 1 of F-box only protein OS=Bos taurus OX=9913 GN=FBXO48 PE=4 SV=1 CANONICAL=G3N250-1" }, "locus": { "chromosome": "11", "start_pos": 66863061, "end_pos": 66862025, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063569.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063569.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055955.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055955.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:786890", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786890", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C0I6-1", "protein_name": "F-box protein 48", "gene_name": "FBXO48", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMQKTPKRNKQPLTAGEPALLPPDKRRKGAPADFVALLPPEVSVQIFSSLDLRSLCSAAMTCRRWRLAIDGNDWLWRNHCLTVRAVCQREIDGDRGSGYSWKITLLRNYWKSKVKQEWLSGKYSNVHSQNNLPEKSMYPMDVDTWGEILEAELER", "length": 155 }, "evidence": [ { "id": "G3N250", "url": "https://omabrowser.org/oma/group/G3N250/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SJ08-1", "protein_name": "F-box only protein", "gene_name": "FBXO48", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKNSQRNHHSRELSSEDAEKEKKENQNNFVELLPPEVTFKIFSQLDIRSLCRASMTCRSWNQTIRHSDSLWKPHCLTVRAVCQREIDDDLESGYPWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER", "length": 151 }, "evidence": [ { "id": "G3N250", "url": "https://omabrowser.org/oma/group/G3N250/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5FWF7-1", "protein_name": "F-box only protein 48", "gene_name": "FBXO48", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHKNSKRNNNLRVSHTEANSVDAEKEKNESQNNFFELLPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSLWKPHCMTVRAVCRREIDDDLESGYSWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER", "length": 155 }, "evidence": [ { "id": "G3N250", "url": "https://omabrowser.org/oma/group/G3N250/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CAT8-1", "protein_name": "F-box only protein 48", "gene_name": "Fbxo48", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKTSKKNNNFKIPGTELNSADAERGKEESQRNFVELLPLEVTYKIFSQLDIQSLCRASRTCTGWNCAIRNNDSLWKPHCLTIRAVCQREIDDDIKSGYTWRVILLRNYQKSKVKYEWLSGRYSNIRSPVNLPEKAMCPMDADTWGEILDAELEREVEKLQ", "length": 161 }, "evidence": [ { "id": "G3N250", "url": "https://omabrowser.org/oma/group/G3N250/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "R4GEA9-1", "protein_name": "F-box only protein 48 isoform a", "gene_name": "fbxo48", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVEGAAAPSAGQKLTRWCCSGLQDPLQIERDFSEALPAEMSVRIFGELDVRSLCRASVTCKHWNDIIEGSDHLWRSHCLTGLAVCRREVNGDRLDGCSWKVTLVRNYRKGCVKRRWLKGRYSNIRSADELPANSMCPLDVETWGEILEAELER", "length": 154 }, "evidence": [ { "id": "G3N250", "url": "https://omabrowser.org/oma/group/G3N250/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "G3N250", "url": "https://www.uniprot.org/uniprotkb/G3N250" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N250-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 155, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N250-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N250" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N250", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N250" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 79, "start_aa": "Asn", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N262-1", "uniprot_ac": "G3N262", "uniprot_id": "G3N262_BOVIN", "mass": { "chemical_mass": 29930.0, "monoisotopic_mass": 29930.0 }, "refseq": {}, "gene_names": [ { "name": "RPS3A", "type": "recommended", "evidence": [ { "id": "G3N262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N262" } ] }, { "name": "LOC132344361", "type": "synonym", "evidence": [ { "id": "G3N262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N262" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein eS1", "type": "recommended", "evidence": [ { "id": "G3N262", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N262/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role during erythropoiesis through regulation of transcription factor DDIT3.", "evidence": [ { "database": "UniProtKB", "id": "G3N262", "url": "https://www.uniprot.org/uniprotkb/G3N262#function" }, { "database": "HAMAP", "id": "MF_03122", "url": "https://hamap.expasy.org/signature/MF_03122" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N262", "url": "https://www.uniprot.org/uniprotkb/G3N262" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPS3A", "url": "https://www.uniprot.org/uniprotkb/G3N262", "locus": { "chromosome": "17", "start_pos": 6717402, "end_pos": 6722090, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009908", "url": "https://www.ensembl.org/id/ENSBTAG00000009908" } ] } } ], "crossref": [ { "id": "G3N262", "url": "https://alphafold.ebi.ac.uk/entry/G3N262", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006383", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006383", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MCEIITR", "url": "https://omabrowser.org/oma/group/MCEIITR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N262", "url": "https://www.orthodb.org/?gene=G3N262", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N262", "url": "https://www.uniprot.org/uniprotkb/G3N262", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N262-1", "url": "https://www.uniprot.org/uniprotkb/G3N262-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVGKNKCLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTSVTRTQGTKITSDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPFHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV", "length": 264, "header": "tr|G3N262-1|G3N262_BOVIN Isoform 1 of Small ribosomal subunit protein eS1 OS=Bos taurus OX=9913 GN=RPS3A PE=3 SV=1 CANONICAL=G3N262-1" }, "isoforms": [ { "isoform_ac": "G3N262-1", "url": "https://www.uniprot.org/uniprotkb/G3N262/entry", "sequence": { "sequence": "MAVGKNKCLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTSVTRTQGTKITSDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPFHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV", "length": 264, "header": "tr|G3N262-1|G3N262_BOVIN Isoform 1 of Small ribosomal subunit protein eS1 OS=Bos taurus OX=9913 GN=RPS3A PE=3 SV=1 CANONICAL=G3N262-1" }, "locus": { "chromosome": "X", "start_pos": 119015358, "end_pos": 119014567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008373.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008373.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055969.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055969.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": 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"G3N267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N267/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N267", "url": "https://www.uniprot.org/uniprotkb/G3N267" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3N267", "locus": {} } ], "crossref": [ { "id": "G3N267", "url": "https://alphafold.ebi.ac.uk/entry/G3N267", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047647", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047647", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00165", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00165", "database": "CDD", "categories": [ 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"https://www.ebi.ac.uk/interpro/entry/IPR036986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WMLDELT", "url": "https://omabrowser.org/oma/group/WMLDELT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11581", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11581", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11581:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11581:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00900", "database": "Pfam", 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N267", "url": "https://www.uniprot.org/uniprotkb/G3N267", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N267-1", "url": "https://www.uniprot.org/uniprotkb/G3N267-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGPKKHLKYVAAPKHWMLDELTGVFAPRPSTGPHKLRECLPLFIFLRNRLKYALTGDEVKKICMQRFTKIDGKVCTDITYPAGFMDVISIDKTGENFHLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNGTIQIDLETGKITDFIKFDTGNLCMVTGGASLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVFGKGNKPWISLPRGKGICLTIAEERDKRLAAKQSSG", "length": 263, "header": "tr|G3N267-1|G3N267_BOVIN Isoform 1 of 40S ribosomal protein S4 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=G3N267-1" }, "isoforms": [ { "isoform_ac": "G3N267-1", "url": "https://www.uniprot.org/uniprotkb/G3N267/entry", "sequence": { "sequence": "MARGPKKHLKYVAAPKHWMLDELTGVFAPRPSTGPHKLRECLPLFIFLRNRLKYALTGDEVKKICMQRFTKIDGKVCTDITYPAGFMDVISIDKTGENFHLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNGTIQIDLETGKITDFIKFDTGNLCMVTGGASLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVFGKGNKPWISLPRGKGICLTIAEERDKRLAAKQSSG", "length": 263, "header": "tr|G3N267-1|G3N267_BOVIN Isoform 1 of 40S ribosomal protein S4 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=G3N267-1" }, "locus": { "chromosome": "8", "start_pos": 65713392, "end_pos": 65712604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063361.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063361.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055974.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055974.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-BTA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-BTA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-BTA-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-BTA-72695", "name": "", "url": 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"id": "R-BTA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-BTA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P22090-1", "protein_name": "Small ribosomal subunit protein eS4, Y isoform 1", "gene_name": "RPS4Y1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDEVKKICMQRFIKIDGKVRVDVTYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITVEEAKYKLCKVRKITVGVKGIPHLVTHDARTIRYPDPVIKVNDTVQIDLGTGKIINFIKFDTGNLCMVIGGANLGRVGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGNGNKPWISLPRGKGIRLTVAEERDKRLATKQSSG", "length": 263 }, "evidence": [ { "id": "G3N267", 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"MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDAARGKEESADKAHEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKEKYDDLEDDDDDDDEDGERDLAPSKPVTSSPLTGVEAPPLLSPPPEAAPRGGGGGKTPLGSRTSPGAPPAASKPKLWSLAEIATSDLKQPSLGPGCAPPGLPAAAAPASSGAPPGGSPYPASPLLGRHLYYTSPFYGSYTNYGNLNAALQGQGLLRYNSAAAAPGEALHAAPKAASDAGKAGAHPLPEPHYRPPGGGYEPKKDASEGCTVVGGGVQPYL", "length": 476, "header": "tr|G3N2B2-1|G3N2B2_BOVIN Isoform 1 of Iroquois homeobox 2 OS=Bos taurus OX=9913 GN=IRX2 PE=3 SV=2 CANONICAL=G3N2B2-1" }, "locus": { "chromosome": "20", "start_pos": 70042416, "end_pos": 70038568, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063219.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063219.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056023.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056023.2" } ] } } ], 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"https://omabrowser.org/oma/group/G3N2B2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LNN7-1", "protein_name": "Iroquois homeobox 2", "gene_name": "Irx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAAGFPSYMGSPYDTHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDASRSKEENPDKAQDGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDPLCESGSECKDKFEDLEDEEDDEDECERDLVPPKPVTSSPLTGVEAPLLSPAPEAAPRGGSGGKTPLGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASSGAPPGGSPYSASPLLGRHLYYTSPFYGNYTNYGNLNAALQGQGLLRYNTAASSPGETLHAIPKAASDAGKAGSHSLESHYRPPGGGYEPKKGRCHNCFGKKKSGGHSPFPSS", "length": 478 }, "evidence": [ { "id": "G3N2B2", "url": "https://omabrowser.org/oma/group/G3N2B2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81066-1", "protein_name": "Iroquois-class homeodomain protein IRX-2", "gene_name": "Irx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGSPLQYSADAAAAAAAGFPSYVGSPYDTHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEGDASRSKEESSDKAQDGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRAGDALCESGSECKDKFEDLEDEEDEEDECERDLAPPKPVTSSPLTGVEAPLLSPAPEAAPRGGSGGKTPLGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAPPGGSPYSASPLLGRHLYYTSPFYGNYTNYGNLNAALQGQGLLRYNTAASSPGETLHAMPKAASDTGKAGSHSLESHYRPPGGGYEPKKDTSEGCAVVGAGVQTYL", "length": 474 }, "evidence": [ { "id": "G3N2B2", "url": "https://omabrowser.org/oma/group/G3N2B2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZI1-1", "protein_name": "Iroquois-class homeodomain protein IRX-2", "gene_name": "IRX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"name": "proximal/distal pattern formation involved in metanephric nephron development", "id": "GO:0072272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072272", "evidence": [ { "database": "UniProtKB", "id": "G3N2B2", "url": "https://www.uniprot.org/uniprotkb/G3N2B2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3N2B2", "url": "https://www.uniprot.org/uniprotkb/G3N2B2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N2B2", "url": "https://www.uniprot.org/uniprotkb/G3N2B2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", 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"tr|G3N2C9-1|G3N2C9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR51F5 PE=3 SV=2 CANONICAL=G3N2C9-1" }, "isoforms": [ { "isoform_ac": "G3N2C9-1", "url": "https://www.uniprot.org/uniprotkb/G3N2C9/entry", "sequence": { "sequence": "MPSFNQSTFHPTVFFLTGIPGFETYHAWIFIPFCCLYVIAISGNGMILFIIITESSLHEPMYYFLSMLSFSDLGLCLSTLVTMVGIFWFNTREISFDACIGQMFFIHGFTLMESSVLLAMAFDRYIAICNPLRYATILTNSTIIKVGFAIVVRVTTVVVPLLLLLKRLSFCGSHVLHHSYCFHPDVMKLSCTDTRINSAFGLAIVISTAALDSVLILLSYVLIIRSVLNIASPEERKKAFGTCVSHTSAVAIFYIPTISLSLVHRFGKHAPPLVHTLIANMYLLIPPVMNPIIYSVKTKQIRKAMVKIFLSKLI", "length": 314, "header": "tr|G3N2C9-1|G3N2C9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR51F5 PE=3 SV=2 CANONICAL=G3N2C9-1" }, "locus": { "chromosome": "15", "start_pos": 48691714, "end_pos": 48690773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064832.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064832.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056041.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056041.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783707", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783707", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N2C9", "url": "https://www.uniprot.org/uniprotkb/G3N2C9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N2C9", "url": "https://www.uniprot.org/uniprotkb/G3N2C9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N2C9", "url": "https://www.uniprot.org/uniprotkb/G3N2C9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "G3N2C9", "url": "https://www.uniprot.org/uniprotkb/G3N2C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2C9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2C9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2C9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2C9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2F2-1", "uniprot_ac": "G3N2F2", "uniprot_id": "G3N2F2_BOVIN", "mass": { "chemical_mass": 60972.0, "monoisotopic_mass": 60972.0 }, "refseq": { "ac": "NP_001152881", "name": "prolyl 4-hydroxylase subunit alpha-2 isoform 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152881" }, "gene_names": [ { "name": "P4HA2", "type": "recommended", "evidence": [ { "id": "G3N2F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" } ] }, { "name": "P4HA2", "type": "synonym", "evidence": [ { "id": "NP_001152881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152881" } ] } ], "protein_names": [ { "name": "procollagen-proline 4-dioxygenase", "type": "recommended", "evidence": [ { "id": "G3N2F2", "database": "UniProtKB", "url": 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}, { "database": "UniProtKB", "id": "ARBA00002035", "url": "https://www.uniprot.org/uniprotkb/ARBA00002035#function" }, { "database": "UniProtKB", "id": "F1MJQ4", "url": "https://www.uniprot.org/uniprotkb/F1MJQ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2F2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "P4HA2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2", "locus": { "chromosome": "7", "start_pos": 22218084, "end_pos": 22185143, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001116", "url": "https://www.ensembl.org/id/ENSBTAG00000001116" } ] } } ], "crossref": [ { "id": "G3N2F2", "url": "https://alphafold.ebi.ac.uk/entry/G3N2F2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001116", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001116", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507327", "url": "https://www.ncbi.nlm.nih.gov/gene/507327", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MLLMAWF", "url": "https://omabrowser.org/oma/group/MLLMAWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MJQ4", "url": "https://www.orthodb.org/?gene=F1MJQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N2F2", "url": "https://www.orthodb.org/?gene=G3N2F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10869:SF244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10869:SF244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23558", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23558", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001152881", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001152881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1MJQ4", "url": "https://www.uniprot.org/uniprotkb/F1MJQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MJQ4-1", "url": "https://www.uniprot.org/uniprotkb/F1MJQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2F2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2F2-1", "url": "https://www.uniprot.org/uniprotkb/G3N2F2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPWESTLLVAWFGVLSCVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLSKIKSWADKMEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALEDLVLQNSAADFIANLSVQRQFFPTDEDETGAAKALMRLQDTYKLDPDTISKGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTSKAQVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLHYFERLLEEEREKMLSNHTEAELASQQGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNLRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRKDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD", "length": 535, "header": "tr|G3N2F2-1|G3N2F2_BOVIN Isoform 1 of procollagen-proline 4-dioxygenase OS=Bos taurus OX=9913 GN=P4HA2 PE=3 SV=1 CANONICAL=G3N2F2-1" }, "isoforms": [ { "isoform_ac": "F1MJQ4-1", "url": "https://www.uniprot.org/uniprotkb/F1MJQ4/entry", "sequence": { "sequence": "MKPWESTLLVAWFGVLSCVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLSKIKSWADKMEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALEDLVLQNSAAGNLLSSFSPLEDFIANLSVQRQFFPTDEDETGAAKALMRLQDTYKLDPDTISKGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTSKAQVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLHYFERLLEEEREKMLSNHTEAELASQQGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNLRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD", "length": 544, "header": "tr|F1MJQ4-1|F1MJQ4_BOVIN Computationally mapped isoform of procollagen-proline 4-dioxygenase OS=Bos taurus OX=9913 GN=P4HA2 PE=3 SV=3 CANONICAL=G3N2F2-1" }, "locus": { "chromosome": "7", "start_pos": 22217693, "end_pos": 22194280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001479.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001479.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001479.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001479.5" } ] } }, { "isoform_ac": "G3N2F2-1", "url": "https://www.uniprot.org/uniprotkb/G3N2F2/entry", "sequence": { "sequence": "MKPWESTLLVAWFGVLSCVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLSKIKSWADKMEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALEDLVLQNSAADFIANLSVQRQFFPTDEDETGAAKALMRLQDTYKLDPDTISKGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTSKAQVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLHYFERLLEEEREKMLSNHTEAELASQQGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNLRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRKDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD", "length": 535, "header": "tr|G3N2F2-1|G3N2F2_BOVIN Isoform 1 of procollagen-proline 4-dioxygenase OS=Bos taurus OX=9913 GN=P4HA2 PE=3 SV=1 CANONICAL=G3N2F2-1" }, "locus": { "chromosome": "7", "start_pos": 22217693, "end_pos": 22194280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064203.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064203.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056064.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ASK1-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "P4ha2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLQVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 535 }, "evidence": [ { "id": "G3N2F2", "url": "https://omabrowser.org/oma/group/G3N2F2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L769-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "P4HA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLQVSMLLVAWFGVLNCVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLSKIKSWASKMEALTSQSAADPEGYLAHPVNAYKLVKRLNTDWPVLEDLVLQDSAAGFIANLSVQRQFFPTDEDEAGAAKALMRLQDTYKLDPDTISRGDLPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTSKAQVLDYLSYAVFQLGDLHRALELTRRLLSLDPGHERAGGNLRYFERLLEEEREKMLSNHTEAGPSTPGGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRTPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRKDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD", "length": 535 }, "evidence": [ { "id": "G3N2F2", "url": "https://omabrowser.org/oma/group/G3N2F2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q60716-1", "protein_name": "Prolyl 4-hydroxylase subunit alpha-2", "gene_name": "P4ha2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLQVLVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 537 }, "evidence": [ { "id": "G3N2F2", "url": "https://omabrowser.org/oma/group/G3N2F2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "G3N2F2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "G3N2F2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "G3N2F2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "G3N2F2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "G3N2F2", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2F2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 535, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2F2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2F2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F2" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 412, "end_pos": 520, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.2", "ec_name": "L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2.", "evidence": [ { "id": "1.14.11.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.2" }, { "id": "1.14.11.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 264, "end_pos": 266 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2G4-1", "uniprot_ac": "G3N2G4", "uniprot_id": "G3N2G4_BOVIN", "mass": { "chemical_mass": 52524.0, "monoisotopic_mass": 52524.0 }, "refseq": {}, "gene_names": [ { "name": "GXYLT2", "type": "recommended", "evidence": [ { "id": "G3N2G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G4" } ] } ], "protein_names": [ { "name": "UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase", "type": "recommended", "evidence": [ { "id": "G3N2G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G4/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.42", "type": "synonym", "evidence": [ { "id": "G3N2G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.", "evidence": [ { "database": "UniProtKB", "id": "G3N2G4", "url": "https://www.uniprot.org/uniprotkb/G3N2G4#function" }, { "database": "UniProtKB", "id": "ARBA00037301", "url": "https://www.uniprot.org/uniprotkb/ARBA00037301#function" }, { "database": "UniProtKB", "id": "F1MPT0", "url": "https://www.uniprot.org/uniprotkb/F1MPT0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2G4", "url": "https://www.uniprot.org/uniprotkb/G3N2G4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GXYLT2", "url": "https://www.uniprot.org/uniprotkb/G3N2G4", "locus": { "chromosome": "22", "start_pos": 28727641, "end_pos": 28809023, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020481", "url": "https://www.ensembl.org/id/ENSBTAG00000020481" } ] } } ], "crossref": [ { "id": "G3N2G4", "url": "https://alphafold.ebi.ac.uk/entry/G3N2G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020481", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020481", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507299", "url": "https://www.ncbi.nlm.nih.gov/gene/507299", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507299", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507299", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46012:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46012:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "56064", "url": "https://www.rhea-db.org/rhea/56064", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MPT0", "url": "https://www.uniprot.org/uniprotkb/F1MPT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPT0-1", "url": "https://www.uniprot.org/uniprotkb/F1MPT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2G4", "url": "https://www.uniprot.org/uniprotkb/G3N2G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2G4-1", "url": "https://www.uniprot.org/uniprotkb/G3N2G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLRNKAAALLLLALAALLLALLSLRAGRAAPPAPLSRPASTPPRRAAPAPARLPGWSALPGAGLSARRRRPPRLRPRAGRRGAVSLRKSARRPGELRSFQAVLPPELWIHLAVVACGNRLEETLVMLKSAVLFSHRKMQFHIFTEESLKPEFDKQLRQWPDSYTKKFEHRIYPITFSAGNPQEWKKLFKPCAAQRLFLPVILRDVDSLLYVDTDVLFLRPVDDIWKLLRQFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSAQFKNSMISTGLAWEDMLYPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCREAEREGVSVLHGNRGVYHDEKQPTFKALYEAIRDPDRLLCPRDCPSKKTGVGCHFLFQGIPDPEIKPASASPALPASAVSLSRQSLSIHVLPSSAEVFGDCAHFMWTNSTSFSEAN", "length": 465, "header": "tr|G3N2G4-1|G3N2G4_BOVIN Isoform 1 of UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase OS=Bos taurus OX=9913 GN=GXYLT2 PE=3 SV=3 CANONICAL=G3N2G4-1" }, "isoforms": [ { "isoform_ac": "F1MPT0-1", "url": "https://www.uniprot.org/uniprotkb/F1MPT0/entry", "sequence": { "sequence": "MKLRNKAAALLLLALAALLLALLSLRAGRAAPPAPLSRPASTPPRRAAPAPARLPGWSALPGAGLSARRRRPPRLRPRAGRRGAVSLRKSARRPGELRSFQAVLPPELWIHLAVVACGNRLEETLVMLKSAVLFSHRKMQFHIFTEESLKPEFDKQLRQWPDSYTKKFEHRIYPITFSAGNPQEWKKLFKPCAAQRLFLPVILRDVDSLLYVDTDVLFLRPVDDIWKLLRQFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSAQFKNSMISTGLAWEDMLYPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCREAEREGVSVLHGNRGVYHDEKQPTFKALYEAIRDFPFQDNLFQSMYYPLQLKFLETVHTLCGRIPQVFLKQIEKTMKRAYEKHVIIHVGPNQMH", "length": 443, "header": "tr|F1MPT0-1|F1MPT0_BOVIN Computationally mapped isoform of UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase OS=Bos taurus OX=9913 GN=GXYLT2 PE=3 SV=4 CANONICAL=G3N2G4-1" }, "locus": { "chromosome": "22", "start_pos": 28808824, "end_pos": 28728645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027290.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027290.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027290.7", "url": "https://www.ensembl.org/id/ENSBTAP00000027290.7" } ] } }, { "isoform_ac": "G3N2G4-1", "url": "https://www.uniprot.org/uniprotkb/G3N2G4/entry", "sequence": { "sequence": "MKLRNKAAALLLLALAALLLALLSLRAGRAAPPAPLSRPASTPPRRAAPAPARLPGWSALPGAGLSARRRRPPRLRPRAGRRGAVSLRKSARRPGELRSFQAVLPPELWIHLAVVACGNRLEETLVMLKSAVLFSHRKMQFHIFTEESLKPEFDKQLRQWPDSYTKKFEHRIYPITFSAGNPQEWKKLFKPCAAQRLFLPVILRDVDSLLYVDTDVLFLRPVDDIWKLLRQFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSAQFKNSMISTGLAWEDMLYPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCREAEREGVSVLHGNRGVYHDEKQPTFKALYEAIRDPDRLLCPRDCPSKKTGVGCHFLFQGIPDPEIKPASASPALPASAVSLSRQSLSIHVLPSSAEVFGDCAHFMWTNSTSFSEAN", "length": 465, "header": "tr|G3N2G4-1|G3N2G4_BOVIN Isoform 1 of UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase OS=Bos taurus OX=9913 GN=GXYLT2 PE=3 SV=3 CANONICAL=G3N2G4-1" }, "locus": { "chromosome": "22", "start_pos": 28808824, "end_pos": 28728712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063772.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063772.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056076.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056076.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:507299", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507299", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N2G4", "url": "https://www.uniprot.org/uniprotkb/G3N2G4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { 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"name": "OTUD1", "type": "recommended", "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ] }, { "name": "OTUD1", "type": "synonym", "evidence": [ { "id": "XP_010809497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809497" } ] } ], "protein_names": [ { "name": "OTU domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1/entry#names_and_taxonomy" } ] }, { "name": "OTU domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_010809497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809497" } ] } ], "function": [ { "annotation": "Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin. Required for the stability and translation of a subset mRNAs with a high abundance of rare codons by mediating deubiquitination of 40S ribosomal protein RPS10/eS10, thereby antagonizing ZNF598-mediated 40S ubiquitination. The abundance of rare codons in mRNAs can limit the translation rate and can lead to ribosome collisions that trigger activation of ribosome quality control (RQC) pathway by ZNF598. OTUD1-mediated deubiquitination prevents activation of the RQC and subsequent dissociation of ribosomes and stimulates formation of polysomes and translation.", "evidence": [ { "database": "UniProtKB", "id": "G3N2I1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1#function" }, { "database": "UniProtKB", "id": "ARBA00057633", "url": "https://www.uniprot.org/uniprotkb/ARBA00057633#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2I1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OTUD1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1", "locus": { "chromosome": "13", "start_pos": 24543066, "end_pos": 24387492, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047752", "url": "https://www.ensembl.org/id/ENSBTAG00000047752" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047752", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047752", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "104968459", "url": "https://www.ncbi.nlm.nih.gov/gene/104968459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:104968459", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:104968459", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTHYPSG", "url": "https://omabrowser.org/oma/group/CTHYPSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N2I1", "url": "https://www.orthodb.org/?gene=G3N2I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5357786", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357786", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357905", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5357956", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010809497", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809497", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N2I1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2I1-1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLYSSVCTHYPAGGQGPTAATAAPPAAATATSFKVSLQPPGPAGGAPEPETGECQPAAAAEPREAAAAPAAKMPAFSSCFEMVSGAAAPASAAAAGPPGGSCKPPLPPHYTSTAQITVRALGADRLLLRGPEPGAAAPAAPRGRCLLLAPAAGAPIPPRRGSSAWLLEELLRPDGPEPAGLDATREGPDRNFRLSEHRQALAAAKHRGPAPPPGSPEPGPGPWAEERPAERNLRGWDRAGDRRDAPGAEEPGRPDPEAEAAPARSGEAAPGGATEAVIVSRSDPRDEKLALYLAEVERQDKYLRQRNKYRFHIIPDGNCLYRAVSKAVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDTWCRQTQVQRKRDEELAKSMAISLSKMYIEQNACS", "length": 481, "header": "tr|G3N2I1-1|G3N2I1_BOVIN Isoform 1 of OTU domain-containing protein 1 OS=Bos taurus OX=9913 GN=OTUD1 PE=4 SV=2 CANONICAL=G3N2I1-1" }, "isoforms": [ { "isoform_ac": "G3N2I1-1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1/entry", "sequence": { "sequence": "MQLYSSVCTHYPAGGQGPTAATAAPPAAATATSFKVSLQPPGPAGGAPEPETGECQPAAAAEPREAAAAPAAKMPAFSSCFEMVSGAAAPASAAAAGPPGGSCKPPLPPHYTSTAQITVRALGADRLLLRGPEPGAAAPAAPRGRCLLLAPAAGAPIPPRRGSSAWLLEELLRPDGPEPAGLDATREGPDRNFRLSEHRQALAAAKHRGPAPPPGSPEPGPGPWAEERPAERNLRGWDRAGDRRDAPGAEEPGRPDPEAEAAPARSGEAAPGGATEAVIVSRSDPRDEKLALYLAEVERQDKYLRQRNKYRFHIIPDGNCLYRAVSKAVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDTWCRQTQVQRKRDEELAKSMAISLSKMYIEQNACS", "length": 481, "header": "tr|G3N2I1-1|G3N2I1_BOVIN Isoform 1 of OTU domain-containing protein 1 OS=Bos taurus OX=9913 GN=OTUD1 PE=4 SV=2 CANONICAL=G3N2I1-1" }, "locus": { "chromosome": "13", "start_pos": 24533992, "end_pos": 24533656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065106.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065106.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056095.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056095.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:104968459", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:104968459", "resource": "KEGG Pathway" }, { "id": "R-BTA-5357786", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357786", "resource": "Reactome", "description": "TNFR1-induced proapoptotic signaling" }, { "id": "R-BTA-5357905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357905", "resource": "Reactome", "description": "Regulation of TNFR1 signaling" }, { "id": "R-BTA-5357956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357956", "resource": "Reactome", "description": "TNFR1-induced NF-kappa-B signaling pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZYB8-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQLYSSVCTHFPAGGPGPTAPAPPAAAAAAPFKVSLQPPGPASGAPEPETGECQSAAAAEPREAAVAAPASKMPAFSSCFEVVSGAAAPATAAAAGPPGGSCKPPLPPHYTSTAQITVRALGADRLLLRSPEPGAAAPTAPRGRCLLLAPASGAPVPPRRGSSAWLLEELLRPDCPEPAGLDAAREGPDRNFRLSEHRQALAAAKHRGPAPPPGSPEPGPWAEERPAERSLRGWDRAGDRGDSPGADEPRRPDPEAQATPARSGEAAPGGAAEAVIVSRSDPRDEKLALYLAEVERQDKYLRQRNKYRFHIIPDGNCLYRAVSKAVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDTWCRQTQVQRKRDEELAKSMAISLSKMYIEQNACS", "length": 478 }, "evidence": [ { "id": "G3N2I1", "url": "https://omabrowser.org/oma/group/G3N2I1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XN55-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQLYSSVITHYPAGGTAPPSAAAVFKVSIPPGPSSADSASDAAGPSPNPTAESPAKDGPSPGGPAAAMPAFSSCLEVMPSGPAAAVPQYSSCAQLTVSRRRPLERVVPIRLLPRPEPAPHGRAWLEGVVQSGAEEPSNRSLRLSEHCQALQAAASQPGPQPERGGEDEEGGGGGAAGARRAERSEKLALYLAEVEKQDRYLRQKGRFRFHIIPDGNCLYRAVCKAVYGDQRPHGELREQTVHYIADHLDHFGPIIEGDVGEFLIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRPESPTVSTMVHYLGPEDPTRPSIWLSWLSNGHYDAVLDRVCPNPEYEAWCRQTQVQRRRDEELAKSMAVSLSKMYIEQNACS", "length": 378 }, "evidence": [ { "id": "G3N2I1", "url": "https://omabrowser.org/oma/group/G3N2I1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZNC0-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "Otud1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLYSSVCTHYPAGTPGPTAAAPPATTAAFKVSLQSAGPAAAAPEPDTGERPPAAATEPREAAAAAAMPAFSACFERSGSATAAAPPGACCKPPLPPHFTSTAHIAVRALGAERLLLPPPSAPAPPRRGSSAWLLEELLRPDEPAAPNAARDAPDRNFRLSEHRQALAAAQHRAPAPAPVGPEPGAGPWSEERRTERSPRGWDRASGRSDASGADAHRRPDPEIEVHPVPAPAPAPARSSGDPTQNGEGEAVGAPRADPRDEKLALYLAEVERQDKYLRQRNKYRFHIIPDGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMVHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDNWCKQTQMQRKRDEELAKSMAISLSKMYIEQNACS", "length": 455 }, "evidence": [ { "id": "G3N2I1", "url": "https://omabrowser.org/oma/group/G3N2I1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQLYSSVCTHYPAGAPGPTAAAPAPPAAATPFKVSLQPPGAAGAAPEPETGECQPAAAAEHREAAAVPAAKMPAFSSCFEVVSGAAAPASAAAGPPGASCKPPLPPHYTSTAQITVRALGADRLLLHGPDPVPGAAGSAAAPRGRCLLLAPAPAAPVPPRRGSSAWLLEELLRPDCPEPAGLDATREGPDRNFRLSEHRQALAAAKHRGPAATPGSPDPGPGPWGEEHLAERGPRGWERGGDRCDAPGGDAARRPDPEAEAPPAGSIEAAPSSAAEPVIVSRSDPRDEKLALYLAEVEKQDKYLRQRNKYRFHIIPDGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDNWCKQTQVQRKRDEELAKSMAISLSKMYIEQNACS", "length": 481 }, "evidence": [ { "id": "G3N2I1", "url": "https://omabrowser.org/oma/group/G3N2I1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CUB6-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "Otud1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLYSSVCTHYPAGTPGPTAAAPPATAAAAFKVSLQSASPAAAAPEPDTGERPPAAATEPREAAAAAAMPAFSACFERSGSAAAPPGACSKPPLPPHFTSTAHIAVRALGAERLLLPPPSAPSPPRRGSSAWLLEELLRPDEPAAPNAVRDAPDRNFRLSEHRQALAASQHRAPAPAPVGPEPGAGPGSGPWGEERRAERSSRGWDRASGRSDASGSDALRRQDPEAEAHPVPAPARSSGEPAQNGEGEAVGTSRADPRDEKLALYLAEVERQDKYLRQRNKYRFHIIPDGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDNWCKQTQIQKKRDEELAKSMAISLSKMYIEQNACS", "length": 454 }, "evidence": [ { "id": "G3N2I1", "url": "https://omabrowser.org/oma/group/G3N2I1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3N2I1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "G3N2I1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "G3N2I1", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-140978", "name": "TRADD:TRAF2:RIP1 binds FADD", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-140978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-140978" } ] }, { "id": "R-BTA-5357776", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95KV1-1", "Q95KV0-1", "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "E1BMK3-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357776", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357776" } ] }, { "id": "R-BTA-5357845", "name": "K63polyUb-RIPK1 is deubiquitinated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357845" } ] }, { "id": "R-BTA-5357860", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "E1BMK3-1", "G3N2I1-1", "Q5E953-1", "A2VDU3-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357860" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NI58", "gene_name": "XIAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] } ] }, { "uniprot_ac": "A0ABI0NXY8", "gene_name": "OTUD7B", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0ABI0NXY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXY8" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0ABI0NXY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXY8" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A6QR55", "gene_name": "USP4", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A6QR55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR55" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A6QR55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR55" } ] } ] }, { "uniprot_ac": "E1B9D9", "gene_name": "TRAF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D9" } ] } ] }, { "uniprot_ac": "E1BMK3", "gene_name": "RNF31", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMK3" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMK3" } ] } ] }, { "uniprot_ac": "G3N2I1", "gene_name": "OTUD1", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" } ] } ] }, { "uniprot_ac": "Q1RMU2", "gene_name": "CYLD", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q1RMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMU2" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q1RMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMU2" } ] } ] }, { "uniprot_ac": "Q2KHV7", "gene_name": "USP2", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q2KHV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KHV7" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q2KHV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KHV7" } ] } ] }, { "uniprot_ac": "Q5E953", "gene_name": "UFC1", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q5E953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E953" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q5E953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E953" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q95KV1", "gene_name": "CHUK", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I1" }, { "id": "PS50802", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OTU", "eco_id": "ECO_0000259", "start_pos": 309, "end_pos": 438, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 19 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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taurus OX=9913 GN=OR2T6 PE=3 SV=3 CANONICAL=G3N2I4-1" }, "isoforms": [ { "isoform_ac": "G3N2I4-1", "url": "https://www.uniprot.org/uniprotkb/G3N2I4/entry", "sequence": { "sequence": "MNGNNKTFSSDFTLAGLFTNNKASGFLFSIICAIFFMAIIVNGVVIFLIYIDPHLHTPMYFLLSHLSFIDIMYISTIVPKMLADYLEGERTISFIACTAQYFLYMGFVGAEFFLLGLMAYDRYVAICNPLRYPVLMSHRVCWMILASSWFGGALDSFLLTPITMTLPFCASHKINHFFCEAPTMLRLACGDKAAYEMVMYICCVMMLLIPFSVVIASYAGVLITVHQMKSAEGKKKAFATCSSHMMVVILFYGAALYTYMLPQSYHTPTKDKVFSVFYTIITPLLNPLIYSLRNRDVAEAFKRVLARCL", "length": 309, "header": "tr|G3N2I4-1|G3N2I4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2T6 PE=3 SV=3 CANONICAL=G3N2I4-1" }, "locus": { "chromosome": "7", "start_pos": 42055346, "end_pos": 42054420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064439.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064439.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056099.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056099.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N2I4", "url": "https://www.uniprot.org/uniprotkb/G3N2I4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N2I4", "url": "https://www.uniprot.org/uniprotkb/G3N2I4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N2I4", "url": "https://www.uniprot.org/uniprotkb/G3N2I4" } ], 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"categories": [ "Gene Expression" ] }, { "id": "540117", "url": "https://www.ncbi.nlm.nih.gov/gene/540117", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540117", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540117", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DICKTRC", "url": "https://omabrowser.org/oma/group/DICKTRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N2N1", "url": "https://www.orthodb.org/?gene=G3N2N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005227636", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227636", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N2N1", "url": "https://www.uniprot.org/uniprotkb/G3N2N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2N1-1", "url": "https://www.uniprot.org/uniprotkb/G3N2N1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSGVWFLSVLTVAGILETESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKLMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSTGDSAQRGGHTDTHIPRLSPTLNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQMVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLFPAMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDGPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKRVPSVPRSANNLDVSSFQLQYGSYNTETQDKADGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEPATLAYTISATELLEKQAPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFTPSYESRRQNQDRINKTVLYGTPRKCFVGQSKADHPLLQAKPQSEPDYLEVLEKQTAISQL", "length": 844, "header": "tr|G3N2N1-1|G3N2N1_BOVIN Isoform 1 of SLIT and NTRK like family member 2 OS=Bos taurus OX=9913 GN=SLITRK2 PE=3 SV=1 CANONICAL=G3N2N1-1" }, "isoforms": [ { "isoform_ac": "G3N2N1-1", "url": "https://www.uniprot.org/uniprotkb/G3N2N1/entry", "sequence": { "sequence": "MLSGVWFLSVLTVAGILETESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKLMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSTGDSAQRGGHTDTHIPRLSPTLNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQMVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLFPAMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDGPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKRVPSVPRSANNLDVSSFQLQYGSYNTETQDKADGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEPATLAYTISATELLEKQAPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFTPSYESRRQNQDRINKTVLYGTPRKCFVGQSKADHPLLQAKPQSEPDYLEVLEKQTAISQL", "length": 844, "header": "tr|G3N2N1-1|G3N2N1_BOVIN Isoform 1 of SLIT and NTRK like family member 2 OS=Bos taurus OX=9913 GN=SLITRK2 PE=3 SV=1 CANONICAL=G3N2N1-1" }, "locus": { "chromosome": "NKLS02002203.1", "start_pos": 206541, "end_pos": 204408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072588.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072588.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057272.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057272.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540117", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540117", "resource": "KEGG Pathway" }, { "id": "R-BTA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1DP42-1", "protein_name": "SLIT and NTRK like family member 2", "gene_name": "SLITRK2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSGVWFLSVFTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSSSGSGGDSGQRGSHADTHVQRQSPTLNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPAMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTILSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRSANNLDVSSFQLQYGSYNTETQDKADGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEPATLAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPDHPLLQAKPQSEPDYLEVLEKQTAISQL", "length": 849 }, "evidence": [ { "id": "G3N2N1", "url": "https://omabrowser.org/oma/group/G3N2N1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZK41-1", "protein_name": "SLIT and NTRK-like family, member 2", "gene_name": "Slitrk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSGVWFLSVFTVAGILQIESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISTIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASGDSSQRSSHSDTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVALTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYTSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDNPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRSATNLDVSSFQLQYGSYNTETNDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQDFSYGNLEEKKEEPATLAYTISATELLEKQATPKEPELLYQNIAERAKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPDHPLLQAKPQSEPDYLEVLEKQTAISQL", "length": 846 }, "evidence": [ { "id": "G3N2N1", "url": "https://omabrowser.org/oma/group/G3N2N1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NEZ4-1", "protein_name": "SLIT and NTRK like family member 2", "gene_name": "LOC121106448", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLKGVWLLSLLTVAGILQIESRKPTKDICSKSRCPCEEKENVLNINCENKGFTTISLLLPPPSKIYQLFLNGNALTRLFPNEFVNYSNAVTLHLGNNDMQEIHTGAFSGLRTLKRLHLNNNKLEVLKEDTFLGLESLEYLQADYNYISAIEAGAFNKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKMMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSSSDSNQREKHPIISDPHVSKLLPTANSAINPTRAPKASRPPKARNRPTPRVTVSKDRQIFGPIMVYQTKSPVPITCPDGCICTSQSLDNGLNVNCQEKKISNISELHPKPTTPKKLYLTSNYLQVIYRTDLAEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEILYPSMFDGLQSLQYLYLEYNVIKEILPHTFDTLSNLHLLFLNNNLLRSLPDNVFGGTSLTRLNLRNNHFSHLPVRGVLDRLSALIQIDLQENPWDCTCDIMGLRNWIEQVTDQNSQQSNPPVVINEVICESPTKHSGEHLKFLSKEAICPENPSLSESSLLPMNQNTDMPHLLGISPSSYPEIHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVQSMPSSANNLDISSFQLQYGSYNTETHDKTEGHVYNYITPPVGQMCQNPIYMQKEGDPVAYYRNLHEFSYNSLDHKKEDPTSFAFTISEAELLEKQSSPREPELLYQNIAERVKELPTGGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKYFAEQCKPEHPLLQGKLQTEPDYLEVLEKQTAVSQL", "length": 857 }, "evidence": [ { "id": "G3N2N1", "url": "https://omabrowser.org/oma/group/G3N2N1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QE14-1", "protein_name": "SLIT and NTRK-like protein 2", "gene_name": "slitrk2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLNNILLLSVLTVTSFPSKTDSRKTSKDICKNRCSCEEKENALNINCENKAFTTVSLFQPPQNKISQLFLNGNFLTKISPNEFLNYGNVTSLHLGNNGLQEIKTGAFNGLKNLKRLHLNNNNLEIIREDTFSGLESLEYLQADYNYISAIEAGAFNKLNKLKVLILNDNLLLSLPNNIFRFVMLTHLDLRGNRLKTLPFAGVLEHIGGIMEIQLEENPWNCTCDLIPLKAWLDTISVYVGDIVCETPFRLHGKDVTQLIKQDLCPRRNPGDASHRAMQPPSDSQYQGLSPTLRPRVTPTRAPKASRPPKMRYRPTPRVTSSRDKHVFGPIMVYQTRSPVPMTCPGICVCTSQNPDSGLNINCQERKLQNISELQPKPSYPKKLHLTGNYLQIIYRTDLTEYSSLELLHLGNNRIAIIQDGAFENLTSLRRLYLNGNYIESLSQSLFAGLQSLQYLYLEYNIIKEILPHTFNSLHNLQLLFLNNNLLRSLPDNVFGGTMLTRLNLRNNHFSHLPVRGVLDQLSAFIQIDLQENPWDCTCNIVELKNWMELSSTSVVVNEITCDSPSKHAGRLLRSLRNDAICPETDEVSVTKPPTVVSSSTEATPPSSVTPTDRMPEMPPEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVENVPSGTNNHLDLNSFQVQYGSYNADVNADKSDNHVYNYIPPPVGQMCQNPIYMQKESEQVAYYRNLKELSFNTLDPKKEELDRSPTFTISTVEFIDKQPCANREPELLYQNIVERAKDLPQSGPLSYNFCTLPKKSFIPPYETSRRLNQDRLNKTVLYGTPRKYAAQSKNEHPLLSNKLKTEPDYLEVLEKQTAMSQL", "length": 854 }, "evidence": [ { "id": "G3N2N1", "url": "https://omabrowser.org/oma/group/G3N2N1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q810C0-1", "protein_name": "SLIT and NTRK-like protein 2", "gene_name": "Slitrk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISTIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASGDSSQRSSHSDTHVQRLTPTTNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVALTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPENPNLSDGTILSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPNVPRNATNLDVSSFQLQYGSYNTETNDKADGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQDFSYGNLEEKKEEPATLAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPDHPLLQAKPQSEPDYLEVLEKQTAISQL", "length": 846 }, "evidence": [ { "id": "G3N2N1", "url": "https://omabrowser.org/oma/group/G3N2N1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H156-1", "protein_name": "SLIT and NTRK-like protein 2", "gene_name": "SLITRK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGSHADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQTAISQL", "length": 845 }, "evidence": [ { "id": "G3N2N1", "url": "https://omabrowser.org/oma/group/G3N2N1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "G3N2N1", "url": "https://www.uniprot.org/uniprotkb/G3N2N1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N2N1", "url": "https://www.uniprot.org/uniprotkb/G3N2N1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "G3N2N1", "url": "https://www.uniprot.org/uniprotkb/G3N2N1" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "G3N2N1", "url": "https://www.uniprot.org/uniprotkb/G3N2N1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2N1" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 264, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N2N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2N1" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 64, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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"evidence": [ { "id": "G3N2N2", "url": "https://omabrowser.org/oma/group/G3N2N2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D818-1", "protein_name": "Suppressor APC domain-containing protein 2", "gene_name": "Sapcd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVAAMAERGRLSHAAPAPSTEGLPRAFLQSLRTLFDILDDRQRGYVHLREIESRWQGADARELPCGVLEGLRQVAPANGYLTFERFVAGLRTSLLKADGGQRDQARVAARPGDQSSLQQRLMFAPADEPRTVLERKPLPLSACPASGGPSGTSRNPELLCVPVEAASCPTETERPLSKALEQIPSADLGAAACKTLGKGTGEARQAPRARGERRRHTITNGVDCSLLKQMKELDQEQEVLLQGLEMMARGRDWYQQQLQRVQERQRRLSQSRAAADFGAEGSPRPLGRLLPKVQEVARCLGELLTAACSGRALPSSSLGPLGPPSPSTPVWQQQTILMLKEQNRLLTQEVTDKSERITQLEQEKSALIKQLFEARALSQQDSGPLDSTFI", "length": 391 }, "evidence": [ { "id": "G3N2N2", "url": "https://omabrowser.org/oma/group/G3N2N2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W115-1", "protein_name": "Suppressor APC 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"NP_001376781", "name": "olfactory receptor family 6 subfamily C member 4C", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376781" }, "gene_names": [ { "name": "OR6C4C", "type": "recommended", "evidence": [ { "id": "G3N2Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2Q4" } ] }, { "name": "OR6C4C", "type": "synonym", "evidence": [ { "id": "NP_001376781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376781" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3N2Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2Q4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C4", "type": "synonym", "evidence": [ { "id": "NP_001376781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376781" } ] }, { "name": "olfactory receptor family 6 subfamily C member 4C", "type": "synonym", "evidence": [ { "id": "NP_001376781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376781" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376781" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N2Q4", "url": "https://www.uniprot.org/uniprotkb/G3N2Q4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2Q4", "url": "https://www.uniprot.org/uniprotkb/G3N2Q4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR6C4C", "url": "https://www.uniprot.org/uniprotkb/G3N2Q4", "locus": { "chromosome": "5", "start_pos": 57855480, "end_pos": 57856406, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000057988", "url": "https://www.ensembl.org/id/ENSBTAG00000057988" } ] } } ], "crossref": [ { "id": "G3N2Q4", "url": "https://alphafold.ebi.ac.uk/entry/G3N2Q4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510046", "url": "https://www.ncbi.nlm.nih.gov/gene/510046", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"MKIFFRYQTFRFIWLTKPIGRRFHKSHQLGAPLTLADFEAINRCERSLPKNFNFAGDVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFGELGSLSRKAANVLTKPCGLERGDRVAVILPRIPEWWLINVACMRTGLVFMPGTTQLTAKDILYRLHASKAKCIVASEEVIPAVESIVSECPDLKTKLLVSPHSQDGWLSFPELFQTASAEHSCVETGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYTLCGRYWLDLKSTDIIWNMSDTGWIKAAIGSVFSSWLQGACVFVHRMAQFDTDTFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYKFKKLRHCLTGGEPLNPEVLEQWKVQTGLELYEGYGQTEVGIICANQKGQEIKPGSMGKGVLPYDVQIIDENGNILPPGKEGEIALRLTSTRPFCFFSEYVDNPEKTAATIRGNFYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPVRGEVVKAFVVLSAPFKSSNPEKLTLELQDHVKKSTAPYKYPRKVEFVKELPKTITGKIKRNVLRDHEWGRT", "length": 580, "header": "tr|G3N2S1-1|G3N2S1_BOVIN Isoform 1 of medium-chain acyl-CoA ligase OS=Bos taurus OX=9913 GN=ACSM4 PE=3 SV=1 CANONICAL=G3N2S1-1" }, "isoforms": [ { "isoform_ac": "G3N2S1-1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1/entry", "sequence": { "sequence": "MKIFFRYQTFRFIWLTKPIGRRFHKSHQLGAPLTLADFEAINRCERSLPKNFNFAGDVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFGELGSLSRKAANVLTKPCGLERGDRVAVILPRIPEWWLINVACMRTGLVFMPGTTQLTAKDILYRLHASKAKCIVASEEVIPAVESIVSECPDLKTKLLVSPHSQDGWLSFPELFQTASAEHSCVETGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYTLCGRYWLDLKSTDIIWNMSDTGWIKAAIGSVFSSWLQGACVFVHRMAQFDTDTFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYKFKKLRHCLTGGEPLNPEVLEQWKVQTGLELYEGYGQTEVGIICANQKGQEIKPGSMGKGVLPYDVQIIDENGNILPPGKEGEIALRLTSTRPFCFFSEYVDNPEKTAATIRGNFYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPVRGEVVKAFVVLSAPFKSSNPEKLTLELQDHVKKSTAPYKYPRKVEFVKELPKTITGKIKRNVLRDHEWGRT", "length": 580, "header": "tr|G3N2S1-1|G3N2S1_BOVIN Isoform 1 of medium-chain acyl-CoA ligase OS=Bos taurus OX=9913 GN=ACSM4 PE=3 SV=1 CANONICAL=G3N2S1-1" }, "locus": { "chromosome": "25", "start_pos": 18448492, "end_pos": 18426076, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064764.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064764.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056189.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056189.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100299006", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299006", "resource": "KEGG Pathway" }, { "id": "R-BTA-177128", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-177128", "resource": "Reactome", "description": "Conjugation of salicylate with glycine" }, { "id": "R-BTA-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FQV7-1", "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "LOC100755056", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKILLHYQRFRFIWLAKPAGRHFHKHPQLQTPLTLADFEAINRCEKPLPKNFNFAADVLDQWSQKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACIRTGLVFMPGTTQLTRKDILYRLQASKAKCIVASEEVAPAVDSIVSECPNLKTKLLVSPDRWDGWLNFQELLPLASEEHSCVETGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTPSDIMWNMSDTGWIKAAIGSVFSTWLQGACVFVHRMAQFDTDTFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYQFKRLRHCLTGGEPLNPEVLEQWKVQTGLELYEGYGQTEVGIICANCKGQEIKPGSMGKGVVPYDVQIIDESGNVLPPGKEGEIALRLESTRPFCFFSEYVDNPEKTAATIRRNFYVTGDRGVMDNDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLIAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580 }, "evidence": [ { "id": "G3N2S1", "url": "https://omabrowser.org/oma/group/G3N2S1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LSY0-1", "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "ACSM4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKIFSCYQTFRFIRLTKPPGRRFHKDYQLQVPLTLDDLEAIMLCERPLPKSFNFAADVLDQWSQKEKTGERPANPALWWVNSQGNEVKWSFRELGSLSRKAANVLTKSCGLERGDRVAMILPRIPEWWLLNVACMRTGLVFMPGTTQLTAKDLLYRLRASKAKCIVASDEVVPAVESAASECPDLKTKLLVSPHSRNGWLSFQELFQNASTEHSCVETGSQESMAIFFTSGTSGSPKMAQHSQSSLGIGSTHCGRHWFDLKSSDTMWNISDTGWIKASLGSLFSPWLMGSCVFVHRMAQFDTDTVLDVLATYPITTLCGPPTVYRMLVQKDLRRYKFKSLKHCLTGGEPLNPEVLEQWRAQTGLNLYEGYGQTEVGLICASYKGQEIKPGSMGIRAPPHDVQIIDENGDVLPPGKEGEISIRLTPTRHFSLFSKYVDNPEKTAATIRGGFYVTGDRGVMDSDGYFRFVGRADDVIISAGYRIGPFEVESALIEHPAVAESAVVSSPDPIRGEVVKAFVVLSAPFKSSNPEQLTLELQDHVKKSTAPYKYPRKVEFVQELPKTVTGKIKRNILRDREWGRA", "length": 580 }, "evidence": [ { "id": "G3N2S1", "url": "https://omabrowser.org/oma/group/G3N2S1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C7M7-1", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "gene_name": "ACSM4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIFFRYQTFRFIWLTKPPGRRLHKDHQLWTPLTLADFEAINRCNRPLPKNFNFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWRGR", "length": 580 }, "evidence": [ { "id": "G3N2S1", "url": "https://omabrowser.org/oma/group/G3N2S1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q42524-1", "protein_name": "4-coumarate--CoA ligase 1", "gene_name": "4CL1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPQEQAVSQVMEKQSNNNNSDVIFRSKLPDIYIPNHLSLHDYIFQNISEFATKPCLINGPTGHVYTYSDVHVISRQIAANFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGATATAANPFFTPAEIAKQAKASNTKLIITEARYVDKIKPLQNDDGVVIVCIDDNESVPIPEGCLRFTELTQSTTEASEVIDSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSSETEKYDLSSIRVVKSGAAPLGKELEDAVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDDVKQFVSKQVVFYKRINKVFFTESIPKAPSGKILRKDLRAKLANGL", "length": 561 }, "evidence": [ { "id": "G3N2S1", "url": "https://omabrowser.org/oma/group/G3N2S1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q7TN78-1", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "gene_name": "Acsm4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVLLRCQRLRFIWLAKPAGRHFHRDPQLWAPLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEHNCVQTGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFNTDTFLDTLTSYPITTLCSAPTVYRMLVQQDLKRYQFKRLRHCLTGGEPLNPEVLEQWKAQTGLELYEGYGQTEVGIICANRKGEEIKPGSMGKGVVPYDVQIIDEHGNILPSGKEGEIALRLGSDRPFCFFSEYVDNPEKTDATIRRNFYITGDRGVMDDDGYLWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580 }, "evidence": [ { "id": "G3N2S1", "url": "https://omabrowser.org/oma/group/G3N2S1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80W40-1", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "gene_name": "Acsm4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVLLHCQRLRFIWLAKPAGRHFHRDSQLWAPLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIVSECPSLKTKLLVSPHHWDGWLNFQELLQSASEEHNCVETGSQEPMAIYFTSGTTGSPKMAQHSQGSLGIGYTLCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFDTDIFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYQFKRLRHCLTGGEPLNPEVLEQWKMQTGLELYEGYGQTEVGIICANRKGEAIKPGSMGKGVVPYDVQIIDENGNILPSGKEGEIALRLKSDRPFCFFSEYVDNPEKTDATIRRNFYVTGDRGVMDDDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPYKCSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580 }, "evidence": [ { "id": "G3N2S1", "url": "https://omabrowser.org/oma/group/G3N2S1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" }, { "name": "fatty-acyl-CoA synthase activity", "id": "GO:0004321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004321", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" }, { "name": "fatty acid ligase activity", "id": "GO:0015645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015645", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" }, { "name": "medium-chain fatty acid-CoA ligase activity", "id": "GO:0031956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031956", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "G3N2S1", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48340", "name": "", "equation": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5R6-1", "E1BHV3-1", "G3N2S1-1", "F1MES1-1", "F1MPP7-1", "Q9BEA2-1", "Q17QJ1-1" ], "evidence": [ { "id": "48340", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48340" } ] }, { "id": "R-BTA-159567", "name": "ACSM2B-like proteins transform ST to ST-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-159559" ], "output_participant_list": [ "R-ALL-159557" ], "enzyme_list": [ "G3N2S1-1" ], "evidence": [ { "id": "R-BTA-159567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159567" } ] }, { "id": "R-BTA-9749971", "name": "ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-9750012" ], "output_participant_list": [], "enzyme_list": [ "G3N2S1-1" ], "evidence": [ { "id": "R-BTA-9749971", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9749971" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-159557", "participant_name": "ST-CoA [mitochondrial matrix]", "crossref": [ { "id": "32587", "database": "ChEBI", "url": "" }, { "id": "ZINC000096068394", "database": "ZINC", "url": "" }, { "id": "HMDB0011636", "database": "HMDB Metabolite", "url": "" }, { "id": "8147635", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-159559", "participant_name": "ST [mitochondrial matrix]", "crossref": [ { "id": "30762", "database": "ChEBI", "url": "" }, { "id": "ZINC000000001554", "database": "ZINC", "url": "" }, { "id": "C00805", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-9750012", "participant_name": "2,5-DHBA [mitochondrial matrix]", "crossref": [ { "id": "58044", "database": "ChEBI", "url": "" }, { "id": "ZINC000000001507", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9S5R6", "gene_name": "ACSM2B", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0AAA9S5R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5R6" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "A0AAA9S5R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5R6" } ] } ] }, { "uniprot_ac": "E1BHV3", "gene_name": "ACSM5", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "E1BHV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHV3" } ] } ] }, { "uniprot_ac": "F1MES1", "gene_name": "ACSM3", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MES1" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "F1MES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MES1" } ] } ] }, { "uniprot_ac": "F1MPP7", "gene_name": "ACSM1", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MPP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPP7" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "F1MPP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPP7" } ] } ] }, { "uniprot_ac": "G3N2S1", "gene_name": "ACSM4", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "G3N2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "G3N2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" } ] } ] }, { "uniprot_ac": "Q17QJ1", "gene_name": "ACSF2", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q17QJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ1" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "Q17QJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ1" } ] } ] }, { "uniprot_ac": "Q9BEA2", "gene_name": "ACSM1", "activity": [ { "ec_number": "6.2.1.2", "activity": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q9BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BEA2" } ] }, { "ec_number": "6.2.1.25", "activity": "benzoate + ATP + CoA = benzoyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q9BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BEA2" } ] }, { "ec_number": "6.2.1.2", "activity": "", "evidence": [ { "id": "Q9BEA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9BEA2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2S1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 580, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2S1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2S1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" }, { "id": "PF13193", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-binding enzyme C-terminal", "eco_id": "ECO_0000259", "start_pos": 486, "end_pos": 566, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N2S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2S1" }, { "id": "PF00501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-dependent synthetase/ligase", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 422, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.2.1.2", "ec_name": "a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "6.2.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.2" }, { "id": "6.2.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.2.1.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13392:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192810", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N319-1", "url": "https://www.uniprot.org/uniprotkb/G3N319-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQAGARVSLGGDGAEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPIHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATSHLPHFVPYASLLAEGATPPPASSPAHSFSKAPSASSPPGQLPHHSSTQPLDLAPGRMPIYYQMSRLPAGYTLHETAPAGASPVLTPQEGQPALEAAAANGQRPRDRNLVRRESEALDSPSNKGEGQGLAPVVECMVDGQLFSGSQSARVEVAVPAHRGTPDTDLEVQRVVGALASQDYRAVAAQRKDEPSPLNLSHHNPDHQGGGRGPARSAAEMAEKNQARGVSPHSHQEPLKHRPFPKAVVVANGNLVPAGTDPGLLPVGSEILVASSLDIQARATFPDKESTLPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQSSCAPPGQLGPPRERPERTVLGPREQCDSDGKSQPSGEGSRSVEPSQPEPGAQACWSAPSFQRYSTQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 687, "header": "tr|G3N319-1|G3N319_BOVIN Isoform 1 of Ataxin 1 like OS=Bos taurus OX=9913 GN=ATXN1L PE=3 SV=1 CANONICAL=G3N319-1" }, "isoforms": [ { "isoform_ac": "G3N319-1", "url": "https://www.uniprot.org/uniprotkb/G3N319/entry", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQAGARVSLGGDGAEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPIHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATSHLPHFVPYASLLAEGATPPPASSPAHSFSKAPSASSPPGQLPHHSSTQPLDLAPGRMPIYYQMSRLPAGYTLHETAPAGASPVLTPQEGQPALEAAAANGQRPRDRNLVRRESEALDSPSNKGEGQGLAPVVECMVDGQLFSGSQSARVEVAVPAHRGTPDTDLEVQRVVGALASQDYRAVAAQRKDEPSPLNLSHHNPDHQGGGRGPARSAAEMAEKNQARGVSPHSHQEPLKHRPFPKAVVVANGNLVPAGTDPGLLPVGSEILVASSLDIQARATFPDKESTLPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQSSCAPPGQLGPPRERPERTVLGPREQCDSDGKSQPSGEGSRSVEPSQPEPGAQACWSAPSFQRYSTQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 687, "header": "tr|G3N319-1|G3N319_BOVIN Isoform 1 of Ataxin 1 like OS=Bos taurus OX=9913 GN=ATXN1L PE=3 SV=1 CANONICAL=G3N319-1" }, "locus": { "chromosome": "18", "start_pos": 39242616, "end_pos": 39240556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063114.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063114.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056291.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056291.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 186, "start_aa": "Thr", "end_pos": 186, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr186", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:521025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521025", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBC4-1", "protein_name": "Ataxin 1 like", "gene_name": "Atxn1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPNPLLSPSANLATTHLPHFVPYASLLAEEAAPPPQAASPAQSFTKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQTSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERSVRRESEPLDSTSSKGESQGLVPVVECMVDGQLFSGSQTPRVEVAAPTHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHTLDHQGEGRGSARNPTEVVEKNQTRVFYPQSHQEPVKHRPLPKAVVVANGNLVPTGTDPSLLPVGSEILVASSLDMQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTILGPRDLCDSEGKNQTSGEGSRVGEPSQPEPSAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 679 }, "evidence": [ { "id": "G3N319", "url": "https://omabrowser.org/oma/group/G3N319/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FB74-1", "protein_name": "Ataxin-1-like", "gene_name": "atxn1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKPVHERNQECLPPKKRDLPVNNNNNNTSINTNSNSSSSISGGAGGSGIGPGGAGGGGEDAPSSQSSGANAESQSSEWVRAQTGVHYGVESAEGLVGLPVDQYSMLYKVALPTGTYSPTSLHPVLTHAYTVPSPMLQHTSVPYPPTFPHSSLQFVNPPYPTAVPYAVPPGFVPSSLIPPQSGISQPHLVPYPSVIQEGVVSSQPQPQVSSHAYTKMLAPLVLSSEQAATQVPIGTVGMLPTGELSPRGVPVFYHPAVRGVQSHSSSLEQDREVNGGDRDHGGRESHQDAVYSARSVRLMQTTVLEPQQDKSLKSRRPEGRMSPGQSSTPDTDLEVQQVVGRLASPVHGSSRKDASHVPLNLSQSSQRSRETQGEIRTAYALNPAESRAHQQQIVQQGHAVILANGQPVLVPLDYHHHHQQQQQPQQHHYQPNDVASAAIVASPATYTKAMDAAACLPERAVAEPPPQQGQQVISAPAPGAFPQAPLLAPTGPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEMSGGLKIDSSMVVDIRASQQRPGLVALHFNVGEQQSKVTIDVPPEHPFFVYGQGWSSCSPERTAQLYGLTCHHLQVGDVCVSVTLQQQAASQQKPPQQVQARTPTKANSTSGATPQPMGPPAPQHTPRPQSHLKIHREREHNKEEPMQIGGSRHIDMPPRPNRTSAEHTHSQSNYYLHTEGHAPGVGAASQRRWSAPGFQRYSIKNEDGRLVSAATSGSSRPSFIPQEVKLSIEGRSNAGK", "length": 765 }, "evidence": [ { "id": "G3N319", "url": "https://omabrowser.org/oma/group/G3N319/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HAG9-1", "protein_name": "Ataxin-1-like isoform X1", "gene_name": "Atxn1l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWPRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANIATSHLPHFVPYASLLAEEATPPPQAASPAQPFNKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQMSRLPAGYTLHEAPTAGTSPVLTPQEGQSALEATAANGQRQRERNVVRRESEALDSTSSKSEGQGMVPVVECLVDGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGTLASQDYRVVAAQRKDEPSPLNLSHHTLDHQGEGRGSARNPTELVEKNQARVFYPQSHQEPVKHRPLPKAVVVANGNLVPTGTDPSLLPVGSEILVASSLDMQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTVLGPRDLCDSEGKIQSSGEGSRVGEPSQPEPGAQACWPAPSFQRYSMQGEEARAVLLRPSFIPQEVKLSIEGRSNAGK", "length": 688 }, "evidence": [ { "id": "G3N319", "url": "https://omabrowser.org/oma/group/G3N319/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0C7T5-1", "protein_name": "Ataxin-1-like", "gene_name": "ATXN1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQAGARVSLGGDGAEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPLHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATSHLPHFVPYASLLAEGATPPPQAPSPAHSFNKAPSATSPSGQLPHHSSTQPLDLAPGRMPIYYQMSRLPAGYTLHETPPAGASPVLTPQESQSALEAAAANGGQRPRERNLVRRESEALDSPNSKGEGQGLVPVVECVVDGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKEEPSPLNLSHHTPDHQGEGRGSARNPAELAEKSQARGFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDSGLLPVGSEILVASSLDVQARATFPDKEPTPPPITSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTTQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPSQLGPPRERPERTVLGSRELCDSEGKSQPAGEGSRVVEPSQPESGAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 689 }, "evidence": [ { "id": "G3N319", "url": "https://omabrowser.org/oma/group/G3N319/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0C7T6-1", "protein_name": "Ataxin-1-like", "gene_name": "Atxn1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATTHLPHFVPYASLLAEEATPPPQAASPAQSFNKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQMSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERNVRRESEALDSASSKGESQGLVPVVECMADGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHNLDHQGEGRGSARNPTELVEKSQARVFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDPSLLPVGSEILVASSLDLQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTVLGPRDLCDSEGKNQPSGEGSRVGEPSQPEPGAQACWPAPSFQRFSMQGEEARAAMLRPSFIPQEVKLSIEGRSNAGK", "length": 687 }, "evidence": [ { "id": "G3N319", "url": "https://omabrowser.org/oma/group/G3N319/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "R4GIP3-1", "protein_name": "Ataxin 1 like", "gene_name": "ATXN1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRAGHERSQECLPPKKRDLPAASAGTEAGRAGGAPASTEGPEWARTVGSSAVALRYGPGEAAEAVAGLTVDQYGMLYKVAMPPATFSPTGLHPVVNVSPLTPTFNVTSPIIQHPGVPYPPIHYAQIPPTSLQFIGSHYTVPYAVPPGFLPSPLLSPSSNLTASHVPHFVPYASLFTEEAAPSPQTTSPTHSFNKSSAVSPGQMQHHAGTQPLDTAPGRIPVYYQMSRLPSGYSGYETPTAGGNPDSSQQDSQLSSEVAAANGEQRHLEHNVVRRTSEAADSASSKAEDCLPGSAVRCVVDGQFLSGYQTFRTEVSVPAHRSTPDADLEVQRVVGALASQDYHVLSAQRKDDPSPLNLCHNIPNQQGESKDILRNAVERGAAEKNQSRSPYVVSPEEMVRQKQLTKGMVIANGKPVLVPAGSEPIRSSISEALVRQSPIVQAQGGMLEKDLAQLQPPGSSRLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQDSQWPGLVTLHFVVGEQQSKVSIDVPPEHPFFVYGQGWSSCSPGRTAQVFALTCHRLQVGDVCISISLQSMNGNFASQANYPFTDQLISTRERSEITAQGSREPSDRAAERKTQTERENAAQSSREEPSQPETGSQHSWTAPGFQRYSVQAEEPRHSLLRPSFIPQEVKLSIEGRSNAGK", "length": 690 }, "evidence": [ { "id": "G3N319", "url": "https://omabrowser.org/oma/group/G3N319/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "POZ domain binding", "id": "GO:0031208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031208", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3N319", "url": "https://www.uniprot.org/uniprotkb/G3N319" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N319", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N319" }, { "id": "PS51148", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51148" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AXH", "eco_id": "ECO_0000259", "start_pos": 455, "end_pos": 586, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 186 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 362, "end_pos": 364 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"MSGNNLDVNDKFDEQLRVQEWYRDTKDNGTEKDPGAETDSFRQQPTDTPYEWDLDKKAWFPKITEDFIATYQANYGFSNDGASNSTASVQDVSARTAEEPPQRQPPDPSDLKKKGEKRKTESGWFHVEDDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTGDFKVKLYKDDQGNLKGDGLCCYLKRESVDLALKLLDEGEIRGYRLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSMQQKQLDWRPERQAGSSRMYHERVVIIKNMFHPVDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRSPEEADYCIQTLNGRWFGGRQITAQAWDGTTDCQVEETTSEREERLRGWEAFLNAPEANRGLQRSDSIRAPERAGSSRVRHFSEHPGTSQTNVQAAATEMAFEEPIDEKKFEKMEDGGEVEEAASEKDAKESGPEKEAEGSREESEESCLERESKAACPKREREEDFPERESGEGSPEKEHEEGNPNKESKETVPEKESKKKKLKTDPDKNGHEKESEEEGPGKESEGEASPQKVASEDDDSEQESKDCSEKQFENGSEKELEENGLEKGFEEDASDKEFNENILEKELEENESEKSEFEDDSSEKVFDEEGSEKEFDEESDEKEEEEDAYGKVFDDESEEEDEEDADKKECEDADEKDEEDEKVFEDSDGKEDEEDGDVKEDEDIDEKVFEDDSSEKFFDDDSSDKLSDERGTVGGLGDVKEEGPLSTGSSFVLGSNDDDENDTI", "length": 766, "header": "tr|G3N370-1|G3N370_BOVIN Isoform 1 of 17S U2 SnRNP complex component HTATSF1 OS=Bos taurus OX=9913 GN=HTATSF1 PE=3 SV=3 CANONICAL=G3N370-1" }, "isoforms": [ { "isoform_ac": "G3N370-1", "url": 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CANONICAL=G3N370-1" }, "locus": { "chromosome": "12", "start_pos": 61179015, "end_pos": 61176718, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025363.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025363.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056344.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056344.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3N370", "url": "https://www.uniprot.org/uniprotkb/G3N370" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "G3N370", "url": "https://www.uniprot.org/uniprotkb/G3N370" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N370", "url": "https://www.uniprot.org/uniprotkb/G3N370" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "G3N370", "url": "https://www.uniprot.org/uniprotkb/G3N370" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "G3N370", "url": "https://www.uniprot.org/uniprotkb/G3N370" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", 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Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:107131130", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MLINMHF", "url": "https://omabrowser.org/oma/group/MLINMHF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N388", "url": "https://www.orthodb.org/?gene=G3N388", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002691603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691603", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N388", "url": "https://www.uniprot.org/uniprotkb/G3N388", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N388-1", "url": "https://www.uniprot.org/uniprotkb/G3N388-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRENQSSMSEFLLLGLPIRPEQQGMFFALFLGVYLTTVLGNLLILLLIRLDARLYTPMYFFLSHLALTDISFSSVTVPKMLINMQTQGQSIPYAGCITQMYFFIFFTGLDDFLLTSMAYDRYMAICHPLHYTTVMGQGLCTLLVTVSWILSCANALCHTLLLTRLSFCADHSIPHFFCDLGALLKLSCSDTSLNELAIFTAGVADIILPLVCILISYGHIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFFPSSSTSRDKSTIASVMYTVVTPLLNPFIYSLRNRDMKRALERLLHRAKVLSQ", "length": 313, "header": "tr|G3N388-1|G3N388_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN=OR1J4C PE=3 SV=1 CANONICAL=G3N388-1" }, "isoforms": [ { "isoform_ac": "G3N388-1", "url": "https://www.uniprot.org/uniprotkb/G3N388/entry", "sequence": { "sequence": "MKRENQSSMSEFLLLGLPIRPEQQGMFFALFLGVYLTTVLGNLLILLLIRLDARLYTPMYFFLSHLALTDISFSSVTVPKMLINMQTQGQSIPYAGCITQMYFFIFFTGLDDFLLTSMAYDRYMAICHPLHYTTVMGQGLCTLLVTVSWILSCANALCHTLLLTRLSFCADHSIPHFFCDLGALLKLSCSDTSLNELAIFTAGVADIILPLVCILISYGHIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFFPSSSTSRDKSTIASVMYTVVTPLLNPFIYSLRNRDMKRALERLLHRAKVLSQ", "length": 313, "header": "tr|G3N388-1|G3N388_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN=OR1J4C PE=3 SV=1 CANONICAL=G3N388-1" }, "locus": { "chromosome": "11", "start_pos": 93650141, "end_pos": 93649203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064908.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064908.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056363.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056363.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:107131130", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131130", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AP80-1", "protein_name": "Olfactory receptor", "gene_name": "Or1j4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKDNQSTVSEFILLGLPIKPEEQGMYSALFLAMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLRNMHTQDSSIPYTECIAQMYFFILFTDLDNFLLTSMAYDRYVAICHPLHYTAIMREELCILLVAMSWILSCVSALSHTLLLARLSFCADNTIPHFFCDLAALLKLSCSDISLNELVIFTAGTIVITLPLICILISYGHIGATILKVSSNKGIYKALSTCGSHLSVVSLYYGAIIGLYLIPSSSTSSDKGVIASVMYTVVTPLLNPFIYSIRNRDMKEALKKLVNRAAIST", "length": 312 }, "evidence": [ { "id": "G3N388", "url": "https://omabrowser.org/oma/group/G3N388/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NGS1-1", "protein_name": "Olfactory receptor 1J4", "gene_name": "OR1J4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRENQSSVSEFLLLDLPIWPEQQAVFFTLFLGMYLITVLGNLLIILLIRLDSHLHTPMFFFLSHLALTDISLSSVTVPKMLLSMQTQDQSILYAGCVTQMYFFIFFTDLDNFLLTSMAYDRYVAICHPLRYTTIMKEGLCNLLVTVSWILSCTNALSHTLLLAQLSFCADNTIPHFFCDLVALLKLSCSDISLNELVIFTVGQAVITLPLICILISYGHIGVTILKAPSTKGIFKALSTCGSHLSVVSLYYGTIIGLYFLPSSSASSDKDVIASVMYTVITPLLNPFIYSLRNRDIKGALERLFNRATVLSQ", "length": 313 }, "evidence": [ { "id": "G3N388", "url": "https://omabrowser.org/oma/group/G3N388/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VFP8-1", "protein_name": "Olfactory receptor", "gene_name": "Or1j4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRDNQSMVSEFILLGLPIRPEEQGMYYALFLTMYLTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTVPKMLRNMHIHDPSIPYAECIAQMYFFILFTDLDNFLLTSMAYDRYVAICHPLHYTTIMREELCILLVAISWILSCVSALSHTLLLARLSFCADNTISHFFCDLAALLKLSCSDISLNELVIFTVGTTVITLPLICILISYGHIVATILKVSSNKGICKALSTCGSHLSVVSLYYGTIIGVYFIPSSFTSTDKGIVASVMYTVVTPLLNPFIYSIRNRDMKEALKKLFNRASIST", "length": 312 }, "evidence": [ { "id": "G3N388", "url": "https://omabrowser.org/oma/group/G3N388/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N388", "url": "https://www.uniprot.org/uniprotkb/G3N388" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N388", "url": "https://www.uniprot.org/uniprotkb/G3N388" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N388", "url": "https://www.uniprot.org/uniprotkb/G3N388" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3N388", "url": "https://www.uniprot.org/uniprotkb/G3N388" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N388-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N388-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N388" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N388" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3A7-1", "uniprot_ac": "G3N3A7", "uniprot_id": "G3N3A7_BOVIN", "mass": { "chemical_mass": 35614.0, "monoisotopic_mass": 35614.0 }, "refseq": { "ac": "NP_001377707", "name": "olfactory receptor family 2 subfamily AT member 2C", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377707" }, "gene_names": [ { "name": "OR2AT2C", "type": "recommended", "evidence": [ { "id": "G3N3A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3A7" } ] }, { "name": "OR2AT2C", "type": "synonym", "evidence": [ { "id": "NP_001377707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377707" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3N3A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3A7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily AT member 2C", "type": "synonym", "evidence": [ { "id": "NP_001377707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377707" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377707" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N3A7", "url": "https://www.uniprot.org/uniprotkb/G3N3A7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3A7", "url": "https://www.uniprot.org/uniprotkb/G3N3A7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2AT2C", "url": "https://www.uniprot.org/uniprotkb/G3N3A7", "locus": { "chromosome": "15", "start_pos": 54313650, "end_pos": 54314615, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047344", "url": "https://www.ensembl.org/id/ENSBTAG00000047344" } ] } } ], "crossref": [ { "id": "G3N3A7", "url": "https://alphafold.ebi.ac.uk/entry/G3N3A7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047344", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047344", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13954", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13954", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112441641", "url": "https://www.ncbi.nlm.nih.gov/gene/112441641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:112441641", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112441641", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITKFMIP", "url": "https://omabrowser.org/oma/group/ITKFMIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N3A7", "url": "https://www.orthodb.org/?gene=G3N3A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24242:SF253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24242:SF253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381753", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001377707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N3A7", "url": "https://www.uniprot.org/uniprotkb/G3N3A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3A7-1", "url": "https://www.uniprot.org/uniprotkb/G3N3A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METIACNESEESWTIFYLMGIPSLPKSLFLPIFFIFLLLYLLILVGNALILVAVVIEPSLHKPMYFFLINLSALDILFTTTTVPKMLSLFLHGDRYLSFSACFLQMYLFHSFSCSEAFILVVMAYDRYVAICRPLHYPVLMTPQTNAALAASAWLTALLLPIPAVVQTSHLAFDSTVYIYHCFCDHLAVVQASCSDASPQTLMGFCIAMVVSFLPLLLVLLSYAHILASVLHIGSREGRSKAFSTCSSHLLVVGTYYSSIAIACVAYRADLPLDFHIVGNVVYAILTPVLNPLIYTLRNKDVKTAITKMACPWNPNNSAKP", "length": 321, "header": "tr|G3N3A7-1|G3N3A7_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2AT2C PE=3 SV=2 CANONICAL=G3N3A7-1" }, "isoforms": [ { "isoform_ac": "G3N3A7-1", "url": "https://www.uniprot.org/uniprotkb/G3N3A7/entry", "sequence": { "sequence": "METIACNESEESWTIFYLMGIPSLPKSLFLPIFFIFLLLYLLILVGNALILVAVVIEPSLHKPMYFFLINLSALDILFTTTTVPKMLSLFLHGDRYLSFSACFLQMYLFHSFSCSEAFILVVMAYDRYVAICRPLHYPVLMTPQTNAALAASAWLTALLLPIPAVVQTSHLAFDSTVYIYHCFCDHLAVVQASCSDASPQTLMGFCIAMVVSFLPLLLVLLSYAHILASVLHIGSREGRSKAFSTCSSHLLVVGTYYSSIAIACVAYRADLPLDFHIVGNVVYAILTPVLNPLIYTLRNKDVKTAITKMACPWNPNNSAKP", "length": 321, "header": "tr|G3N3A7-1|G3N3A7_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2AT2C PE=3 SV=2 CANONICAL=G3N3A7-1" }, "locus": { "chromosome": "15", "start_pos": 54314615, "end_pos": 54313653, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065864.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065864.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056409.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056409.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:112441641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112441641", "resource": "KEGG Pathway" }, { "id": "R-BTA-381753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381753", "resource": "Reactome", "description": "Olfactory Signaling Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q519-1", "protein_name": "Olfactory receptor", "gene_name": "Or2at1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENIACNGSGNSQTSFYLTGIPSLQKSLFLPVFLIFLLLYLLILVGNALILVAVVTERSLHKPMYFFLINLSALDILFTTTTVPKMLSLLLLGDRFLSFPACFLQMYLFHSFSCSEAFILVVMAYDRYVAICRPLHYPVHMTPQTNTALAASAWITALLLPIPAVIQTSQMAFDNIAYIYHCFCDHLAVVQASCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYARILSSVLRINSKEGRSKAFSTCSSHLLVVGTYYSSIAIAYVAYRADLPLDFHIMGNVVYAILTPVLNPLIYTLRNKDVKSAITKMMCHQDPKSIGKP", "length": 321 }, "evidence": [ { "id": "G3N3A7", "url": "https://omabrowser.org/oma/group/G3N3A7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V8B7-1", "protein_name": "Olfactory receptor", "gene_name": "Or2at1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENIACNGSGDSQTSFYLIGIPSLQKSLFLPVFFIFLLLYLLILMGNTLILVAVVAEPSLHKPMYFFLINLSALDILFTTTTVPKMLSLLLLGDRLLSFPACFLQMYLFHSFSCSEAFILVVMAYDRYVAICRPLHYPVHMTPQTNTALAASAWITALLLPIPAVVQTSHMAFDNIAYIYHCFCDHLAVVQASCSDTSPQTLMGFCIAMVVSFLPLLLVLLSYVRILISVLRINSKEGRSKAFSTCSSHLLVVGTYYSSIAISYVAYRADLPVDFHIMGNVVYAILTPVLNPIIYTLRNKDVKAAITKIVCHQDPKSIGKP", "length": 321 }, "evidence": [ { "id": "G3N3A7", "url": "https://omabrowser.org/oma/group/G3N3A7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N3A7", "url": "https://www.uniprot.org/uniprotkb/G3N3A7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3N3A7", "url": "https://www.uniprot.org/uniprotkb/G3N3A7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N3A7", "url": "https://www.uniprot.org/uniprotkb/G3N3A7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3N3A7", "url": "https://www.uniprot.org/uniprotkb/G3N3A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3A7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 321, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3A7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3A7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3A7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 295, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 316, "end_pos": 318 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3B2-1", "uniprot_ac": "G3N3B2", "uniprot_id": "G3N3B2_BOVIN", "mass": { "chemical_mass": 42132.0, "monoisotopic_mass": 42132.0 }, "refseq": { "ac": "XP_005213234", "name": "alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213234" }, "gene_names": [ { "name": "ST6GALNAC4", "type": "recommended", "evidence": [ { "id": "G3N3B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ] }, { "name": "SIAT7B", "type": "synonym", "evidence": [ { "id": "XP_005213234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213234" } ] }, { "name": "ST6GALNAC2", "type": "synonym", "evidence": [ { "id": "XP_005213234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213234" } ] }, { "name": "ST6GALNAC4", "type": "synonym", "evidence": [ { "id": "XP_005213234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213234" } ] }, { "name": "st6GalNAc-IV", "type": "synonym", "evidence": [ { "id": "XP_005213234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213234" } ] } ], "protein_names": [ { "name": "alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetylgalactosaminide6-alpha-sialyltransferase", "type": "recommended", "evidence": [ { "id": "G3N3B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B2/entry#names_and_taxonomy" } ] }, { "name": "2.4.3.7", "type": "synonym", "evidence": [ { "id": "G3N3B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B2/entry#names_and_taxonomy" } ] }, { "name": "alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005213234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213234" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ST6GALNAC4", "url": "https://www.uniprot.org/uniprotkb/G3N3B2", "locus": { "chromosome": "11", "start_pos": 98573693, "end_pos": 98582940, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046548", "url": "https://www.ensembl.org/id/ENSBTAG00000046548" } ] } } ], "crossref": [ { "id": "G3N3B2", "url": "https://alphafold.ebi.ac.uk/entry/G3N3B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046548", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046548", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23977", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23977", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "404124", "url": "https://www.ncbi.nlm.nih.gov/gene/404124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N3B2", "url": "https://www.orthodb.org/?gene=G3N3B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45906", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45906", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45906:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45906:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-977068", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977068", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005213234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213234", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "41968", "url": "https://www.rhea-db.org/rhea/41968", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "65280", "url": "https://www.rhea-db.org/rhea/65280", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "65284", "url": "https://www.rhea-db.org/rhea/65284", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3B2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSRRIPACPPVSSEAWDPALSVWVLAGPWLPSLPSLIPGGSSHGLLSGSDSMKAPCRLLLIVLCSVGFSAVYILLCYWACLPFCPAFCLDPHLSIKSRPTVPGPLHFSGYSSVPDGKPLVRELCRSCAVVSSSGQMLGSGLGAEIDSAECVLRMNQAPTVGFEADVGQRSTLRVISHTSVPLLLRNYSHYFQQARDTLYVVWGQGKHMDRALGGRTYRALLQLTRMYPGLQVYTFTERMMAYCDQVFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREEHHPSVPYHYFEKGRLDECQMYLAHERAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTQWSHRHSTITRPLLQPHSAKNT", "length": 376, "header": "tr|G3N3B2-1|G3N3B2_BOVIN Isoform 1 of alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetylgalactosaminide6-alpha-sialyltransferase OS=Bos taurus OX=9913 GN=ST6GALNAC4 PE=3 SV=2 CANONICAL=G3N3B2-1" }, "isoforms": [ { "isoform_ac": "G3N3B2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3B2/entry", "sequence": { "sequence": "MGSSRRIPACPPVSSEAWDPALSVWVLAGPWLPSLPSLIPGGSSHGLLSGSDSMKAPCRLLLIVLCSVGFSAVYILLCYWACLPFCPAFCLDPHLSIKSRPTVPGPLHFSGYSSVPDGKPLVRELCRSCAVVSSSGQMLGSGLGAEIDSAECVLRMNQAPTVGFEADVGQRSTLRVISHTSVPLLLRNYSHYFQQARDTLYVVWGQGKHMDRALGGRTYRALLQLTRMYPGLQVYTFTERMMAYCDQVFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREEHHPSVPYHYFEKGRLDECQMYLAHERAPRSAHRFITEKAVFSRWAKKRPIVFAHPSWRTQWSHRHSTITRPLLQPHSAKNT", "length": 376, "header": "tr|G3N3B2-1|G3N3B2_BOVIN Isoform 1 of alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetylgalactosaminide6-alpha-sialyltransferase OS=Bos taurus OX=9913 GN=ST6GALNAC4 PE=3 SV=2 CANONICAL=G3N3B2-1" }, "locus": { "chromosome": "11", "start_pos": 98582765, "end_pos": 98574152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063122.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063122.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056414.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056414.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" }, { "id": "R-BTA-977068", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977068", "resource": "Reactome", "description": "Termination of O-glycan biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ], "pmid": "" }, { "name": "oligosaccharide metabolic process", "id": "GO:0009311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009311", "evidence": [ { "database": "UniProtKB", "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ], "pmid": "" }, { "name": "ganglioside biosynthetic process", "id": "GO:0001574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001574", "evidence": [ { "database": "UniProtKB", "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "id": "GO:0001665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001665", "evidence": [ { "database": "UniProtKB", "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ], "pmid": "" }, { "name": "alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity", "id": "GO:0047290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047290", "evidence": [ { "database": "UniProtKB", "id": "G3N3B2", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "41968", "name": "", "equation": "a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3N3B2-1", "Q08E15-1", "A0A3Q1N3L6-1" ], "evidence": [ { "id": "41968", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41968" } ] }, { "id": "65280", "name": "", "equation": "3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Ser-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-seryl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E15-1", "A0A3Q1N3L6-1", "G3N3B2-1" ], "evidence": [ { "id": "65280", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65280" } ] }, { "id": "65284", "name": "", "equation": "3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Thr-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E15-1", "A0A3Q1N3L6-1", "G3N3B2-1" ], "evidence": [ { "id": "65284", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65284" } ] }, { "id": "R-BTA-4084980", "name": "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-4086301" ], "output_participant_list": [ "R-ALL-4086341" ], "enzyme_list": [ "F1N6V7-1", "G3N3B2-1", "A0A3Q1LRX1-1" ], "evidence": [ { "id": "R-BTA-4084980", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4084980" } ] }, { "id": "R-BTA-981809", "name": "ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3N3B2-1" ], "evidence": [ { "id": "R-BTA-981809", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-981809" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-4086301", "participant_name": "GalNAc-R [Golgi lumen]", "crossref": [ { "id": "21507", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-4086341", "participant_name": "Neu5Ac-2,6-GalNAc-R [Golgi lumen]", "crossref": [ { "id": "62634", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LRX1", "gene_name": "ST6GALNAC2", "activity": [ { "ec_number": "2.4.3.3", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0A3Q1LRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRX1" } ] }, { "ec_number": "2.4.3.3", "activity": "", "evidence": [ { "id": "A0A3Q1LRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRX1" } ] } ] }, { "uniprot_ac": "A0A3Q1N3L6", "gene_name": "ST6GALNAC3", "activity": [ { "ec_number": "2.4.3.7", "activity": "an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc derivative + CMP + H(+).", "evidence": [ { "id": "A0A3Q1N3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3L6" } ] }, { "ec_number": "2.4.3.7", "activity": "", "evidence": [ { "id": "A0A3Q1N3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3L6" } ] } ] }, { "uniprot_ac": "F1N6V7", "gene_name": "ST6GALNAC1", "activity": [ { "ec_number": "2.4.3.3", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "F1N6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ] }, { "ec_number": "2.4.3.3", "activity": "", "evidence": [ { "id": "F1N6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6V7" } ] } ] }, { "uniprot_ac": "G3N3B2", "gene_name": "ST6GALNAC4", "activity": [ { "ec_number": "2.4.3.7", "activity": "an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc derivative + CMP + H(+).", "evidence": [ { "id": "G3N3B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ] }, { "ec_number": "2.4.3.7", "activity": "", "evidence": [ { "id": "G3N3B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B2" } ] } ] }, { "uniprot_ac": "Q08E15", "gene_name": "ST6GALNAC6", "activity": [ { "ec_number": "2.4.99.-", "activity": "", "evidence": [ { "id": "Q08E15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E15" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3B2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 376, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3B2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3B2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00041IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00063MO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00520NI", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00743WU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00745CN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00803TF", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01040ZV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01155GN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01203BZ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01287FH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01325OU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01376HR", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01445XB", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G01546PE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01614ZM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G01657UH", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G01665LU", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02244ID", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02387FV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02473HY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02860LZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G02915XR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03172PR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03325JN", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G03542TR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G03819IX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G03834RX", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03998SF", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04267XF", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04289KQ", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04483QG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G04513DL", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G04548YV", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G04706FE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G04743RS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G04895YD", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G05106AU", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05235KE", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G05374TU", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05412ZS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G05490PJ", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G05570RS", "type": 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}, { "glytoucan_ac": "G20435PF", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G20482JP", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G20826OM", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G20854YP", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G20857JS", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G21573GX", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G21927IY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G22222BH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G22629JM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G22803YZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G22927MQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G23355WV", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G23416CI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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[provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377152", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377152" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N3C4", "url": "https://www.uniprot.org/uniprotkb/G3N3C4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3C4", "url": "https://www.uniprot.org/uniprotkb/G3N3C4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2N1O", "url": "https://www.uniprot.org/uniprotkb/G3N3C4", "locus": { "chromosome": "23", "start_pos": 29771733, "end_pos": 29770795, "strand": "-", "evidence": 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"url": "https://omabrowser.org/oma/group/G3N3W7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "G3N3W7", "url": "https://www.uniprot.org/uniprotkb/G3N3W7" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "G3N3W7", "url": "https://www.uniprot.org/uniprotkb/G3N3W7" } ], "pmid": "" }, { "name": "striated muscle cell differentiation", "id": "GO:0051146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051146", "evidence": [ { "database": "UniProtKB", "id": "G3N3W7", "url": "https://www.uniprot.org/uniprotkb/G3N3W7" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377251" }, "gene_names": [ { "name": "OR6C202", "type": "recommended", "evidence": [ { "id": "G3N3Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y0" } ] }, { "name": "OR6C202", "type": "synonym", "evidence": [ { "id": "NP_001377251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377251" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3N3Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3Y0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6C2", "type": "synonym", "evidence": [ { "id": "NP_001377251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377251" } ] }, { "name": "olfactory receptor family 6 subfamily C member 202", "type": "synonym", "evidence": [ { "id": "NP_001377251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377251" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377251" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N3Y0", "url": "https://www.uniprot.org/uniprotkb/G3N3Y0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3Y0", "url": "https://www.uniprot.org/uniprotkb/G3N3Y0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR6C202", "url": "https://www.uniprot.org/uniprotkb/G3N3Y0", "locus": { "chromosome": "5", "start_pos": 58067915, "end_pos": 58068868, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047825", "url": "https://www.ensembl.org/id/ENSBTAG00000047825" } ] } } ], "crossref": [ { "id": "G3N3Y0", "url": "https://alphafold.ebi.ac.uk/entry/G3N3Y0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "782430", "url": "https://www.ncbi.nlm.nih.gov/gene/782430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:782430", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782430", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MENHTIT", "url": "https://omabrowser.org/oma/group/MENHTIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N3Y0", "url": "https://www.orthodb.org/?gene=G3N3Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26454:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26454:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377251", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N3Y0", "url": "https://www.uniprot.org/uniprotkb/G3N3Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3Y0-1", "url": "https://www.uniprot.org/uniprotkb/G3N3Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENHTITTFILVGLTDDPQLQIPIFMFLFLTYMFSITGNLTIIFLTLMDPHLKTPMYYFLQNFALLEVSFTTACIPRYLYNIATGDRSITYAICIIQVFFTDVFGVTEFFLLAIMSYDRYVAICKPLHYMTIMNSRVCQRLVLCCWISGLLIILPPLILFLNLKFCDSNIIDYFFCDASPILKISCSDTWLIEQLVIVSAVLTFILTLVCVALSYIYIIKTIVRLPSSQQRKRAFSTCSSHMIVVSITYGSCIFVYVKPSAKESVAINKGVAVLMTSIAPMLNPFIYTLRNKQVRQAFSDSFKKLVLVSKKQKTAQA", "length": 317, "header": "tr|G3N3Y0-1|G3N3Y0_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR6C202 PE=3 SV=1 CANONICAL=G3N3Y0-1" }, "isoforms": [ { "isoform_ac": "G3N3Y0-1", "url": 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X686-1", "uniprot_ac": "G3X686", "uniprot_id": "G3X686_BOVIN", "mass": { "chemical_mass": 73941.0, "monoisotopic_mass": 73941.0 }, "refseq": {}, "gene_names": [ { "name": "SELENOO", "type": "recommended", "evidence": [ { "id": "G3X686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X686" } ] } ], "protein_names": [ { "name": "Selenoprotein O", "type": "recommended", "evidence": [ { "id": "G3X686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X686/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X686", "url": "https://www.uniprot.org/uniprotkb/G3X686" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SELENOO", "url": 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"MAALRAALAASLTVARARPPPLGRRPPSACCSALAGAMEPAPRWLAGLRFDNRALRALPVETPPPGPEGAPSAPRPVPGACFSRARPEPLRRPRVVALSEPALALLGLGAPPAAAAAREAREAEAALFFSGNALLPGAEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTEAGERWELQLKGAGPTAFSRQADGRKVLRSSIREFLCSEAMFHLGVPTTRAGSCVSSQSTVVRDAFYDGNPRPEPCAVVLRLAPTFLRFGSFEIFKPRDEHTGRAGPSVGRDDIRLQMLDYVISTFYPEIQACHPGDHVQRHAAFFREVTRRTARLVAEWQCVGFCHGVLNTDNMSIVGLTIDYGPFGFLDRYDPDHVCNASDTAGRYSYSKQPEVCKWNLQKLAEALDPALPLELAEAILAEEFDAEFGRHYLQKMRRKLGLVQTEQEGDGALVAQLLETMHLTGADFTNSFYLLNSFPTAPESPDLDGFLAALTAQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLLALIGTRASLARELERVEQQSRLEQLSEAELHGKNRSRWAAWLHNYRARLEKDREASSDAVTWQAERTRVMRANNPKYVLRNYIAQGAIEAAESGDFSEVRRVLKLLETPYGGEAEAEAAEPAEASEAAEETGGAAGRRRSYSSKPPLWAAELCVT", "length": 677, "header": "tr|G3X686-1|G3X686_BOVIN Isoform 1 of Selenoprotein O OS=Bos taurus OX=9913 GN=SELENOO PE=3 SV=2 CANONICAL=G3X686-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NWY2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWY2/entry", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377149", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377149" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X6C2", "url": "https://www.uniprot.org/uniprotkb/G3X6C2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6C2", "url": "https://www.uniprot.org/uniprotkb/G3X6C2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1I1", "url": "https://www.uniprot.org/uniprotkb/G3X6C2", "locus": { "chromosome": "7", "start_pos": 8044506, "end_pos": 8045447, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000060716", "url": "https://www.ensembl.org/id/ENSBTAG00000060716" } ] } } ], "crossref": [ { "id": "G3X6C2", "url": "https://alphafold.ebi.ac.uk/entry/G3X6C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000053862", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053862", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616125", "url": "https://www.ncbi.nlm.nih.gov/gene/616125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616125", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616125", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAATLMC", "url": "https://omabrowser.org/oma/group/KAATLMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6C2", "url": "https://www.orthodb.org/?gene=G3X6C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377149", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377149", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X6C2", "url": "https://www.uniprot.org/uniprotkb/G3X6C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6C2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6C2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPENQTAVSKFLLLGLSEKPEHQIFLFGLFLPMYLVTIFGNLLIILAIITDSHLHTPMYFFLCNLSLVDIFFSSTTVPKMLVNLWTQSKAIPFAGCLAQMYAFHLFGTMDSFLLAVMAIDRFMAIVHPLHYLAIMSPRVCGLLVVGSWLITNLQSIVHTSLMAQLTFCAASEIPHFFCDLMPLLKLSCSDTHTNELVIFAFGIIMGISPLTCILLSYICIFCAVFKIPSAQGKWKAFSTCGSHLTMVTLFYGTIFAVYLQPASPTSLKKDKVAALMCGVVIPMLNPFIYSLRNKNMKAALRKLFSKAATSQS", "length": 313, "header": "tr|G3X6C2-1|G3X6C2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1I1 PE=3 SV=1 CANONICAL=G3X6C2-1" }, "isoforms": [ { "isoform_ac": "G3X6C2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6C2/entry", "sequence": { "sequence": "MEPENQTAVSKFLLLGLSEKPEHQIFLFGLFLPMYLVTIFGNLLIILAIITDSHLHTPMYFFLCNLSLVDIFFSSTTVPKMLVNLWTQSKAIPFAGCLAQMYAFHLFGTMDSFLLAVMAIDRFMAIVHPLHYLAIMSPRVCGLLVVGSWLITNLQSIVHTSLMAQLTFCAASEIPHFFCDLMPLLKLSCSDTHTNELVIFAFGIIMGISPLTCILLSYICIFCAVFKIPSAQGKWKAFSTCGSHLTMVTLFYGTIFAVYLQPASPTSLKKDKVAALMCGVVIPMLNPFIYSLRNKNMKAALRKLFSKAATSQS", "length": 313, "header": "tr|G3X6C2-1|G3X6C2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1I1 PE=3 SV=1 CANONICAL=G3X6C2-1" }, "locus": { "chromosome": "7", "start_pos": 8045447, "end_pos": 8044509, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003481.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003481.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003481.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003481.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616125", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616125", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SAN8-1", "protein_name": "Olfactory receptor", "gene_name": "OR1I1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPENLTTVSEFLLLGLSEKPEHQSFLFGLFLSIYLVTVFGNLLIILAIISDSHLHTPMYFFLSNLSLIDIFFSSTTIPKMLVNLWTQCQAIPFAGCLAQMYAFHLFGTMDSFLLAVMAIDRFMAIVHPLRYLVIMSACVCGLLVGGAWLITNLQSLVHTCLMAQLTFCAGSEIPHFFCDLMPLLKLSCSDTHTNKLAIFVFGIIMGISPLACILFSYACIFWAVFKIPSAQGKWKAFSTCSSHLTVVSLFYGTIFAVYLQPASPASTQKDKVAALMCGVVIPMLNPFIYSLRNKNMKEALRKLVGKVASSQS", "length": 313 }, "evidence": [ { "id": "G3X6C2", "url": "https://omabrowser.org/oma/group/G3X6C2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60431-1", "protein_name": "Olfactory receptor 1I1", "gene_name": "OR1I1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPEKQTEISEFFLQGLSEKPEHQTLLFTMFLSTYLVTIIGNALIILAIITDSHLHTPMYFFLFNLSLVDTLLSSTTVPKMLANIQAQSRAIPFVGCLTQMYAFHLFGTMDSFLLAVMAIDRFVAIVHPQRYLVLMCSPVCGLLLGASWMITNLQSLIHTCLMAQLTFCAGSEISHFFCDLMPLLKLSGSDTHTNELVIFAFGIVVGTSPFSCILLSYIRIFWTVFKIPSTRGKWKAFSTCGLHLTVVSLSYGTIFAVYLQPTSPSSSQKDKAAALMCGVFIPMLNPFIYSIRNKDMKAALGKLIGKVAVPCPRPEQLLDVYHVPGSLLAARDTEMHPIPYPGGVQSLAGNRDME", "length": 355 }, "evidence": [ { "id": "G3X6C2", "url": "https://omabrowser.org/oma/group/G3X6C2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TQU7-1", "protein_name": "Olfactory receptor family 1 subfamily I member 1", "gene_name": "Or1i2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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taurus OX=9913 GN=METRNL PE=3 SV=1 CANONICAL=G3X6G7-1" }, "isoforms": [ { "isoform_ac": "G3X6G7-1", "url": "https://www.uniprot.org/uniprotkb/G3X6G7/entry", "sequence": { "sequence": "MRGATRAAGGRAGQLWPRPPAPGPGPPPLLLLLAVLLGGAGAQYSSDLCSWKGSGLTHEAHRKEVEQVYLRCSAGTVEWMYPTGALIVNLRPNTFSPSRNLTLCIKPLRGSSGANIYLEKTGELKLLVRDGDLGPGQAPCFGFEQGGLFVEATPQQDISRRTTGFQYELTSRRTGPDLHALLAPCRPCSHTEVLLAVCTSDFVVRGSIQKVTHEPERQESAIHLNVSRLYRQKSRVFRPAPEGEGGGWRGRVSTLLECGVRPGHGEFLFTGHMHFGEAWLGCAPRFKDFQRMYRDAEERGLNPCEMGTE", "length": 309, "header": "tr|G3X6G7-1|G3X6G7_BOVIN Isoform 1 of Meteorin-like protein OS=Bos taurus OX=9913 GN=METRNL PE=3 SV=1 CANONICAL=G3X6G7-1" }, "locus": { "chromosome": "19", "start_pos": 49639511, "end_pos": 49624952, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006285.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006285.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006285.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006285.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534297", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534297", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AFP7-1", "protein_name": "Meteorin-like protein", "gene_name": "METRNL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPLFTSFLNSFGLLTIDASLIPANPLQGESVRGLTHESHKKDVEQVYLRCSEGSIEWMYPTGALIVNLRPNTSPASYKHLTVCIKPFKDSAGANIYLEKTGELKLLVRDGERSPSKVYCFGYDQGGLFVEATPQQDISRKITGFQYELMSRGIASDLHTVSAPCRPCSDTEVLLAVCTSDFVIRGSIQDVTNEAEEQESVIHVGVNKLYRQKSKVFQLTGESGNWRGQIKTLLECGVRPGDGDFLFTGRMHFGEARLGCAPRFKDFQRMYKEAKDKGLNPCEIGPD", "length": 286 }, "evidence": [ { "id": "G3X6G7", "url": "https://omabrowser.org/oma/group/G3X6G7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5RJL6-1", "protein_name": "Meteorin-like protein", "gene_name": 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"MRGAARAAWGRAGQPWPRPPAPGPPPPPLPLLLLLLAGLLGGAGAQYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDSAIHLRVSRLYRQKSRVFEPVPEGDGHWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD", "length": 311 }, "evidence": [ { "id": "G3X6G7", "url": "https://omabrowser.org/oma/group/G3X6G7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VE43-1", "protein_name": "Meteorin-like protein", "gene_name": "Metrnl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGAVWAARRRAGQQWPRSPGPGPGPPPPPPLLLLLLLLLGGASAQYSSDLCSWKGSGLTREARSKEVEQVYLRCSAGSVEWMYPTGALIVNLRPNTFSPAQNLTVCIKPFRDSSGANIYLEKTGELRLLVRDIRGEPGQVQCFSLEQGGLFVEATPQQDISRRTTGFQYELMSGQRGLDLHVLSAPCRPCSDTEVLLAICTSDFVVRGFIEDVTHVPEQQVSVIYLRVNRLHRQKSRVFQPAPEDSGHWLGHVTTLLQCGVRPGHGEFLFTGHVHFGEAQLGCAPRFSDFQRMYRKAEEMGINPCEINME", "length": 311 }, "evidence": [ { "id": "G3X6G7", "url": "https://omabrowser.org/oma/group/G3X6G7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3X6G7", "url": "https://www.uniprot.org/uniprotkb/G3X6G7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "response to cold", "id": "GO:0009409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009409", "evidence": [ { "database": "UniProtKB", "id": "G3X6G7", "url": "https://www.uniprot.org/uniprotkb/G3X6G7" } ], "pmid": "" }, { "name": "brown fat cell differentiation", "id": "GO:0050873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050873", "evidence": [ { "database": "UniProtKB", "id": "G3X6G7", "url": 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"url": "https://www.uniprot.org/uniprotkb/G3X6G8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LGR6", "url": "https://www.uniprot.org/uniprotkb/G3X6G8", "locus": { "chromosome": "16", "start_pos": 80312669, "end_pos": 80398994, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004789", "url": "https://www.ensembl.org/id/ENSBTAG00000004789" } ] } } ], "crossref": [ { "id": "G3X6G8", "url": "https://alphafold.ebi.ac.uk/entry/G3X6G8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004789", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004789", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100336662", "url": "https://www.ncbi.nlm.nih.gov/gene/100336662", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336662", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGVCAGF", "url": "https://omabrowser.org/oma/group/YGVCAGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6G8", "url": "https://www.orthodb.org/?gene=G3X6G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24372:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010811896", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010811896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X6G8", "url": "https://www.uniprot.org/uniprotkb/G3X6G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6G8-1", "url": "https://www.uniprot.org/uniprotkb/G3X6G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAPRLLPLWLCAAALCAPPAAPPPRPRPGCPVPCRCREAGILLWVDCSERGLSTVPAGLDPLTAYLDLSMNSLTELWPGVFHHLRFLEELRLSGNRLAHIPGQAFSGLSSLKILMLQNNRLGGIPAEALWELPGLQSLRLDANLISLVPDRSFEGLTSLRHLWLDDNALTEIPVRALSHLRALQAVTLALNRIGRVPDYAFWNLSSLVVLHLHNNRIRHLGAHSFEGLQNLETLDLNCNQLHEFPVAIQTLGRLQELGFHNNNIRAIPEKAFLGNPLLQTIHFYDNPIQFVGRSAFQHLPGLHTLSLNGATDIQEFPDLRGTTSLESLTLTRAGLQRLPPGMCQQLPRLRVLELSHNRIEGLPSLRGCQKLEEIGLQHNRIWEVRADTFRELTFLRSLDLSWNAIRSIHPEAFSTLRSLVKLDLTGNQLSVLPLAGLGGLVHLKLRGNRALSQAFPKDSFPRLRTLEVPYAYQCCAYSGCPGFFTASGLRGPQHPPPDAQDPPKRTLADRAESRYDLDPEELQLEMEEPRPQPAVQCSPAPGPFQPCEHLFESWGVRLAVWAVVLLALLCNALVLLSLSVAGPGPLPPAKFVVGALAGANALTGLSCGLLASVDALTFGQFAEFGARWEAGPGCRAAGFLAVLGSEASVLLLSLGAAHCSVAAACVRARGKAPAAGSVRAGALGCLALAGLLAALPLASVGEYGASPLCLPHAPPAGRPAALGFAVALVLLHAACLLAAALACIRLSCRLPAAGLEASWDCAAVRHVAWLTFADGLLYCPVAFLSLASALGLLPVTPEAVKAVLLLVLPLPACLNPLLYLLFSPHSREDLRRLRPCWGGPREPSSCDSTQALVAFPDVELTAEASETQGLPLGALVPRQQPGGLKLEGGHVAEPEGTRFGQQPPSRDGGRAQGTPEASLAGRGRAGGGGFQSSGLASGV", "length": 941, "header": "tr|G3X6G8-1|G3X6G8_BOVIN Isoform 1 of Leucine rich repeat containing G protein-coupled receptor 6 OS=Bos taurus OX=9913 GN=LGR6 PE=4 SV=2 CANONICAL=G3X6G8-1" }, "isoforms": [ { "isoform_ac": "G3X6G8-1", "url": "https://www.uniprot.org/uniprotkb/G3X6G8/entry", "sequence": { "sequence": "MPRAPRLLPLWLCAAALCAPPAAPPPRPRPGCPVPCRCREAGILLWVDCSERGLSTVPAGLDPLTAYLDLSMNSLTELWPGVFHHLRFLEELRLSGNRLAHIPGQAFSGLSSLKILMLQNNRLGGIPAEALWELPGLQSLRLDANLISLVPDRSFEGLTSLRHLWLDDNALTEIPVRALSHLRALQAVTLALNRIGRVPDYAFWNLSSLVVLHLHNNRIRHLGAHSFEGLQNLETLDLNCNQLHEFPVAIQTLGRLQELGFHNNNIRAIPEKAFLGNPLLQTIHFYDNPIQFVGRSAFQHLPGLHTLSLNGATDIQEFPDLRGTTSLESLTLTRAGLQRLPPGMCQQLPRLRVLELSHNRIEGLPSLRGCQKLEEIGLQHNRIWEVRADTFRELTFLRSLDLSWNAIRSIHPEAFSTLRSLVKLDLTGNQLSVLPLAGLGGLVHLKLRGNRALSQAFPKDSFPRLRTLEVPYAYQCCAYSGCPGFFTASGLRGPQHPPPDAQDPPKRTLADRAESRYDLDPEELQLEMEEPRPQPAVQCSPAPGPFQPCEHLFESWGVRLAVWAVVLLALLCNALVLLSLSVAGPGPLPPAKFVVGALAGANALTGLSCGLLASVDALTFGQFAEFGARWEAGPGCRAAGFLAVLGSEASVLLLSLGAAHCSVAAACVRARGKAPAAGSVRAGALGCLALAGLLAALPLASVGEYGASPLCLPHAPPAGRPAALGFAVALVLLHAACLLAAALACIRLSCRLPAAGLEASWDCAAVRHVAWLTFADGLLYCPVAFLSLASALGLLPVTPEAVKAVLLLVLPLPACLNPLLYLLFSPHSREDLRRLRPCWGGPREPSSCDSTQALVAFPDVELTAEASETQGLPLGALVPRQQPGGLKLEGGHVAEPEGTRFGQQPPSRDGGRAQGTPEASLAGRGRAGGGGFQSSGLASGV", "length": 941, "header": "tr|G3X6G8-1|G3X6G8_BOVIN Isoform 1 of Leucine rich repeat containing G protein-coupled receptor 6 OS=Bos taurus OX=9913 GN=LGR6 PE=4 SV=2 CANONICAL=G3X6G8-1" }, "locus": { "chromosome": "16", "start_pos": 80398795, "end_pos": 80312992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006288.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006288.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006288.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006288.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336662", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZJU9-1", "protein_name": "Leucine-rich repeat-containing G protein-coupled receptor 6", "gene_name": "Lgr6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSSPLLLALCLCVVLCALARAGSDPQPGPGRPACPAPCHCQEDGIMLSADCSELGLSEVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPRQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSLNGATDIQEFPDLKGTTSLEILTLTRAGIRLLPAGMCQQLPRLRILELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRAIHPEAFSTLRSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCAYGLCANFFKTSGQWQAEDFHAEEEEAPKRPLGLLAGQAENHYDLDLDELQMETEDSKPHPSVQCSPVPGPFKPCEHLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPSPLSPVKLVVGAIAGANALTGISCGLLASVDALTFGQFAEYGARWETGLGCQATGFLAVLGSEASVLLLTLAAVQCSVSVTCVRAYGKAPSPGSVRAGALGCLALAGLAAALPLASVGEYGASPLCLPYAPPEGRPAALGFAVALVMMNSLCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFREDLRRLWPSPRSPGPLAYTAAGELEKSSCDSTQALVAFSDVDLILEASEAGQPPGLETYGFPSVTLISRHQPGATRLEGNHFVEPDGTKLGNPQPPMNEELLLRAEGATLADCSAGGALWPSGPLFASHL", "length": 965 }, "evidence": [ { "id": "G3X6G8", "url": "https://omabrowser.org/oma/group/G3X6G8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UVD5-1", "protein_name": "Leucine-rich repeat-containing G protein-coupled receptor 6", "gene_name": "Lgr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSPPGLLALWLCAVLCASARAGSDPQPGPGRPACPAPCHCQEDGIMLSADCSELGLSVVPADLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLHSLKILMLQSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLHNLETLDLNYNELQEFPLAIRTLGRLQELGFHNNNIKAIPEKAFMGSPLLQTIHFYDNPIQFVGRSAFQYLSKLHTLSLNGATDIQEFPDLKGTTSLEILTLTRAGIRLLPPGVCQQLPRLRILELSHNQIEELPSLHRCQKLEEIGLRHNRIKEIGADTFSQLGSLQALDLSWNAIRAIHPEAFSTLRSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCAYGICASFFKTSGQWQAEDFHPEEEEAPKRPLGLLAGQAENHYDLDLDELQMGTEDSKPHPSVQCSPVPGPFKPCEHLFESWGIRLAVWAIVLLSVLCNGLVLLTVFASGPSPLSPVKLVVGAMAGANALSGISCGLLASVDALTYGQFAEYGARWESGLGCQATGFLAVLGSEASVLLLTLAAVQCSISVTCVRAYGKAPSPGSVRAGALGCLALAGLAAALPLASVGEYGASPLCLPYAPPEGRPAALGFAVALVMMNSLCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLWPSPRSPGPLAYAAAGELEKSSCDSTQALVAFSDVDLILEASEAGQPPGLETYGFPSVTLISRHQPGATRLEGNHFVESDGTKFGNPQPPMKGELLLKAEGATLAGCGSSVGGALWPSGSLFASHL", "length": 967 }, "evidence": [ { "id": "G3X6G8", "url": "https://omabrowser.org/oma/group/G3X6G8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-hormone receptor activity", "id": "GO:0016500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016500", "evidence": [ { "database": "UniProtKB", "id": "G3X6G8", "url": "https://www.uniprot.org/uniprotkb/G3X6G8" } ], "pmid": "" }, { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3X6G8", "url": "https://www.uniprot.org/uniprotkb/G3X6G8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X6G8", "url": "https://www.uniprot.org/uniprotkb/G3X6G8" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "G3X6G8", "url": "https://www.uniprot.org/uniprotkb/G3X6G8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "G3X6G8", "url": "https://www.uniprot.org/uniprotkb/G3X6G8" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "G3X6G8", "url": "https://www.uniprot.org/uniprotkb/G3X6G8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6G8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 941, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6G8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6G8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6G8" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 67, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6I9-1", "uniprot_ac": "G3X6I9", "uniprot_id": "G3X6I9_BOVIN", "mass": { "chemical_mass": 46701.0, "monoisotopic_mass": 46701.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Steroid 21-hydroxylase", "type": "recommended", "evidence": [ { "id": "G3X6I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6I9/entry#names_and_taxonomy" } ] }, { "name": "1.14.14.16", "type": "synonym", "evidence": [ { "id": "G3X6I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6I9/entry#names_and_taxonomy" } ] }, { "name": "21-OHase", "type": "synonym", "evidence": [ { "id": "G3X6I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6I9/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome P-450c21", "type": "synonym", "evidence": [ { "id": "G3X6I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6I9/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome P450 21", "type": "synonym", "evidence": [ { "id": "G3X6I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6I9/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome P450 XXI", "type": "synonym", "evidence": [ { "id": "G3X6I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6I9/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome P450-C21", "type": "synonym", "evidence": [ { "id": "G3X6I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6I9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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"IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QDLMNAW", "url": "https://omabrowser.org/oma/group/QDLMNAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24289:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24289:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X6I9", "url": "https://www.uniprot.org/uniprotkb/G3X6I9", "database": 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"pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glucocorticoid biosynthetic process", "id": "GO:0006704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006704", "evidence": [ { "database": "UniProtKB", "id": "G3X6I9", "url": "https://www.uniprot.org/uniprotkb/G3X6I9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6I9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 413, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6I9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6I9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.14.16", "ec_name": 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{ "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein lipoylation", "id": "GO:0009249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009249", "evidence": [ { "database": "UniProtKB", "id": "G3X6L0", "url": "https://www.uniprot.org/uniprotkb/G3X6L0" } ], "pmid": "" }, { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "G3X6L0", "url": "https://www.uniprot.org/uniprotkb/G3X6L0" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "G3X6L0", "url": "https://www.uniprot.org/uniprotkb/G3X6L0" } ], "pmid": "" }, { "name": "[2Fe-2S] cluster assembly", "id": "GO:0044571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044571", "evidence": [ { "database": "UniProtKB", "id": "G3X6L0", "url": "https://www.uniprot.org/uniprotkb/G3X6L0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6L0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 156, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6L0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6L0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6L0" }, { "id": "PS50075", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50075" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carrier", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 152, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6M4-1", "uniprot_ac": "G3X6M4", "uniprot_id": "G3X6M4_BOVIN", "mass": { "chemical_mass": 37965.0, "monoisotopic_mass": 37965.0 }, "refseq": { "ac": "XP_002698508", "name": "calcium homeostasis modulator protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698508" }, "gene_names": [ { "name": "CALHM1", "type": "recommended", "evidence": [ { "id": "G3X6M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ] }, { "name": "CALHM1", "type": "synonym", "evidence": [ { "id": "XP_002698508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698508" } ] } ], "protein_names": [ { "name": "Calcium homeostasis modulator 1", "type": "synonym", "evidence": [ { "id": "G3X6M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6M4/entry#names_and_taxonomy" } ] }, { "name": "calcium homeostasis modulator protein 1", "type": "synonym", "evidence": [ { "id": "XP_002698508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698508" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CALHM1", "url": "https://www.uniprot.org/uniprotkb/G3X6M4", "locus": { 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"https://omabrowser.org/oma/group/WHRCKPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6M4", "url": "https://www.orthodb.org/?gene=G3X6M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002698508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698508", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6M4-1", "url": "https://www.uniprot.org/uniprotkb/G3X6M4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNAAYSAGILLAPPLVLFLLGLVMNNNVSMLAEEWKRPQGHRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVSLLGNGSLVPGLPPPELARLLARVPCPEIYEGDWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHAHGALAAGPTGSAAPAATEGVDEEREKLHGITDQGTMNRLLTSWHECKPPLRLGQEEPLVGNGWAGGGPRPSRKEVATYFSKV", "length": 344, "header": "tr|G3X6M4-1|G3X6M4_BOVIN Isoform 1 of Calcium homeostasis modulator 1 OS=Bos taurus OX=9913 GN=CALHM1 PE=3 SV=2 CANONICAL=G3X6M4-1" }, "isoforms": [ { "isoform_ac": "G3X6M4-1", "url": "https://www.uniprot.org/uniprotkb/G3X6M4/entry", "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNAAYSAGILLAPPLVLFLLGLVMNNNVSMLAEEWKRPQGHRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVSLLGNGSLVPGLPPPELARLLARVPCPEIYEGDWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHAHGALAAGPTGSAAPAATEGVDEEREKLHGITDQGTMNRLLTSWHECKPPLRLGQEEPLVGNGWAGGGPRPSRKEVATYFSKV", "length": 344, "header": "tr|G3X6M4-1|G3X6M4_BOVIN Isoform 1 of Calcium homeostasis modulator 1 OS=Bos taurus OX=9913 GN=CALHM1 PE=3 SV=2 CANONICAL=G3X6M4-1" }, "locus": { "chromosome": "26", "start_pos": 24042806, "end_pos": 24039335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009263.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009263.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009263.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009263.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 271, "start_aa": "Thr", "end_pos": 271, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr271", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:532026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532026", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZGE7-1", "protein_name": "Calcium homeostasis modulator 1", "gene_name": "CALHM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNVVYSLGILLTPPLVLFLLGLVMNNNISMLAEEWKRPAGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVATLGNGSLVPGLPAPELARLLARVPCPEIYDGNWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQVAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHTHGVLATATATATATEAVQSPSDRTEEEREKLRGITDQGTMNRLLTSWHKCKPPLRLGQEAPLMSNGWAGGEPRPPRKEVATYFSKV", "length": 348 }, "evidence": [ { "id": "G3X6M4", "url": "https://omabrowser.org/oma/group/G3X6M4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AE44-1", "protein_name": "Calcium homeostasis modulator 1", "gene_name": "Calhm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNVVYSMGILLTPPLVLFLLGLVMNNNISMLAEEWKRPLGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVATLGNGSLVPGLPAPELARLLARVPCPEIYDGNWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQVAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHTHGVLATASARTTATEAIQSPSDRTEEEREKLRGITDQGSMNRLLTSWHKCKPPLRLGQEAPLMSNGWAGSEPRPPRKEVATYFSKV", "length": 348 }, "evidence": [ { "id": "G3X6M4", "url": "https://omabrowser.org/oma/group/G3X6M4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S840-1", "protein_name": "Calcium homeostasis modulator 1", "gene_name": "CALHM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNAAYSAGILLAPPLVLFLLGLVMNNNVSMLAEEWKRPPGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVTVLGNGSLVPGLSPPELSRLLARVPCPEIYDGDWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHGHGVLAAAPAGSPAAPATDRAEEEREKLRGITDQGTMNRLLTSWHKCKPPLRLGQKEPLVGNGWAGVGPRPSRKEVATYFSKV", "length": 344 }, "evidence": [ { "id": "G3X6M4", "url": "https://omabrowser.org/oma/group/G3X6M4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8IU99-1", "protein_name": "Calcium homeostasis modulator protein 1", "gene_name": "CALHM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNAAYSAGILLAPPLVLFLLGLVMNNNVSMLAEEWKRPLGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVSALGNGSLAPGLPAPELARLLARVPCPEIYDGDWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHTHGTLATAPASAAAPTTPDGAEEEREKLRGITDQGTMNRLLTSWHKCKPPLRLGQEEPPLMGNGWAGGGPRPPRKEVATYFSKV", "length": 346 }, "evidence": [ { "id": "G3X6M4", "url": "https://omabrowser.org/oma/group/G3X6M4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "plasma membrane raft", "id": "GO:0044853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044853", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "calcium-activated cation channel activity", "id": "GO:0005227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005227", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": 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of monoatomic ion transmembrane transport", "id": "GO:0034765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034765", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "sensory perception of bitter taste", "id": "GO:0050913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050913", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "sensory perception of sweet taste", "id": "GO:0050916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050916", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "sensory perception of umami taste", "id": "GO:0050917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050917", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "G3X6M4", "url": "https://www.uniprot.org/uniprotkb/G3X6M4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6M4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 344, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6M4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6M4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 271 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", 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"sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "G3X6N7", "uniprot_id": "G3X6N7_BOVIN", "mass": { "chemical_mass": 58049.0, "monoisotopic_mass": 58049.0 }, "refseq": { "ac": "NP_001179700", "name": "rab11 family-interacting protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179700" }, "gene_names": [ { "name": "RAB11FIP2", "type": "recommended", "evidence": [ { "id": "G3X6N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ] }, { "name": "RAB11FIP2", "type": "synonym", "evidence": [ { "id": "NP_001179700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179700" } ] } ], "protein_names": [ { "name": "Rab11 family-interacting protein 2", "type": "recommended", "evidence": [ { "id": "G3X6N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6N7/entry#names_and_taxonomy" } ] }, { "name": "rab11 family-interacting protein 2", "type": "synonym", "evidence": [ { "id": "NP_001179700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179700" } ] } ], "function": [ { "annotation": "A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7#function" }, { "database": "UniProtKB", "id": "ARBA00055128", "url": "https://www.uniprot.org/uniprotkb/ARBA00055128#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAB11FIP2", "url": "https://www.uniprot.org/uniprotkb/G3X6N7", "locus": { "chromosome": "26", "start_pos": 38279793, "end_pos": 38319933, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007460", "url": "https://www.ensembl.org/id/ENSBTAG00000007460" } ] } } ], "crossref": [ { "id": "G3X6N7", "url": "https://alphafold.ebi.ac.uk/entry/G3X6N7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007460", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007460", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08682", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08682", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540709", "url": "https://www.ncbi.nlm.nih.gov/gene/540709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540709", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GETHQES", "url": "https://omabrowser.org/oma/group/GETHQES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6N7", "url": "https://www.orthodb.org/?gene=G3X6N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-432040", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179700", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179700", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6N7-1", "url": "https://www.uniprot.org/uniprotkb/G3X6N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRAKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKTDGTFSDTSSAIIPSSHMPDAHTEFSSSEIQMKSKPKKPFLLGPQRLSSAHSMSDLTGAHVCSEKLKSGAVAQTHLLGRQIDSFGAVPESGSLKSPHRRTLSFDTSKMNQPDSSVDAGESAFGRQNDPFTNVTASLPQKFATLPRKKNPFEESSESWDSSVNLFSKSIEVRKENKREKREKVSLFERVTGKKDRRSDKLNNGGADSPCDLKSPNAFSEHRQDYFDYESTNPFTTKFRASNIMPSSSFHVNPTSHEDLRKIPESNPFDATAGYRSLTYEEVLQELVKHKELLRRKDSHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFSNT", "length": 511, "header": "tr|G3X6N7-1|G3X6N7_BOVIN Isoform 1 of Rab11 family-interacting protein 2 OS=Bos taurus OX=9913 GN=RAB11FIP2 PE=4 SV=1 CANONICAL=G3X6N7-1" }, "isoforms": [ { "isoform_ac": "G3X6N7-1", "url": "https://www.uniprot.org/uniprotkb/G3X6N7/entry", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRAKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKTDGTFSDTSSAIIPSSHMPDAHTEFSSSEIQMKSKPKKPFLLGPQRLSSAHSMSDLTGAHVCSEKLKSGAVAQTHLLGRQIDSFGAVPESGSLKSPHRRTLSFDTSKMNQPDSSVDAGESAFGRQNDPFTNVTASLPQKFATLPRKKNPFEESSESWDSSVNLFSKSIEVRKENKREKREKVSLFERVTGKKDRRSDKLNNGGADSPCDLKSPNAFSEHRQDYFDYESTNPFTTKFRASNIMPSSSFHVNPTSHEDLRKIPESNPFDATAGYRSLTYEEVLQELVKHKELLRRKDSHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFSNT", "length": 511, "header": "tr|G3X6N7-1|G3X6N7_BOVIN Isoform 1 of Rab11 family-interacting protein 2 OS=Bos taurus OX=9913 GN=RAB11FIP2 PE=4 SV=1 CANONICAL=G3X6N7-1" }, "locus": { "chromosome": "26", "start_pos": 38319638, "end_pos": 38280601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009814.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009814.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009814.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009814.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540709", "resource": "KEGG Pathway" }, { "id": "R-BTA-432040", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432040", "resource": "Reactome", "description": "Vasopressin regulates renal water homeostasis via Aquaporins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4ID81-1", "protein_name": "Rab11 family-interacting protein 2", "gene_name": "rab11fip2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLGEQSQKWFPTHVQATVLQATDLQPKGKNGTNDAYTIIQLGKEKYSTSVAEKTLNPAWREEASFELPGLLMESNPEVYELCLTVMHRSLVGLDKFLGQKLINLNEIFDNKERRKTDWYTLDSRPGKKRKDRGKIQVSIQFMRNNMTASMFDLSMRDKPRSPFSKLKEKMKGRKHDGAFSDTSSAILPRSGQSETDSLADQHPHSHPQAPTEPKPKRSLLTGTQKLSAAHSMSDLIGTHFRNKLDSMNSIEEKGGASSHRHSQSDGYGCPASDVQCDPFSDIGDNMPQKFATLPRNRNPFEGDQGTLWGADKKEKKEKVGLLGRVTGKKDGKKTGARIGSSGDLRSPNPFTSESTSETNPFLSHYRSSSDNMKNPTSNEDLTQRFKASPEKKQVMKNAREHDLEHLQTSVAAYSNLSFEEVVQELIKQKDVVKKKDAHIRELEDYIDNLLVRVMEETPSILRTPYEPKRKAGKISKK", "length": 478 }, "evidence": [ { "id": "G3X6N7", "url": "https://omabrowser.org/oma/group/G3X6N7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287BJL3-1", "protein_name": "Rab11 family-interacting protein 2", "gene_name": "RAB11FIP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRAKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTFSDTSSAIIPSSHMPDANTEFSSSEIQMKSKPKKPFLLGPQRLSSAHSMSDLTGAHISSEKLKSGAIAQTHLLGRQIEPFGAVPESGSLKSPHRRTLSFDTSKMNQPDSNVEEGESSFGRQSDPFTNVTASLPQKFATLPRKKNPFEESSESWDSSVNLFSKSVEVRKENKREKREKVSLFERVTGKKDSRRSDKLNNGGSDSPCDLKSPNAFSENRQDYFDYESTNPFTTKFRASNIMPSSSFHLNPTSSEDLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFANS", "length": 512 }, "evidence": [ { "id": "G3X6N7", "url": "https://omabrowser.org/oma/group/G3X6N7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A8W0-1", "protein_name": "Rab11 family-interacting protein 2", "gene_name": "Rab11fip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKSDGVFSDTSSAIVPSTHMPDANPEFSSGEMQMKSKPKKPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSTVGPTHLLSHQINSFGVVPESGSLKSPHRRTLSFDTSKLNQPGSIVDEGEHCFGRQSDPFTNVTASLPQKFATLPRKKNPFEESSEPWDSSTNLFSKPIEVRKESKREKREKVSLFERVTGKRDSRRSDKLNNGGSDSPCDLKSPSAFNENRQDYFEYESTNPFTAKFRASTIMPSSSFHMNPTSSDDLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGMDGKPYTRVFLQEVRSWQNPSRSQEQARNSEAHSPDSGMLIIHEDNLTTS", "length": 557 }, "evidence": [ { "id": "G3X6N7", "url": "https://omabrowser.org/oma/group/G3X6N7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BT89-1", "protein_name": "Rab11 family-interacting protein 2", "gene_name": "RAB11FIP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMLAEQAQKWFPTHVQVTVLQAKGLKPKGKSGTNDAYTIIQLGKEKYSTSVAEKTLDPVWKEEASFELPGLLMQENPDRYILYLIVMHRSLVGLDKFLGQVAISLNDVFEDKQRRKTEWFHLESRQGKRTKDRGEIKVNIQFMRNNMTASMFDLSMKDKTKSPFAKLKDKMKGRKNDGTFSDTSSAIIPSTHIPDANVEVCSGEVQMKSKPKKPFLLGPQRLSSAHSMSDLTGSHVSSEKLKSSTVGYSHLFKRQLESFGSVDEGGSLKSPHRRTLSVDTSKMNQQDSTADETGLEAQNDPFTNVSASLPQKFATLPRQKNPFEESSATWDQNINLFSKPVEMKKEIRKEKKEKVSLFERVTGKKDSRRSDKLSNGGSESSTDLKSPGAFGETHQESFDYESTNPFMTNFKPTSMLPSSSFNVNPSGTEDLRKTTDGNPFDTTAGYRNLTYEEVLQELLKHKEQLKKKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFSKS", "length": 510 }, "evidence": [ { "id": "G3X6N7", "url": "https://omabrowser.org/oma/group/G3X6N7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3XA57-1", "protein_name": "Rab11 family-interacting protein 2", "gene_name": "Rab11fip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKSDGVFSDTSSAIVPSTHMPDANPEFSSGEMQMKSKPKKPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSTVGPTHLLSRQIDSFGVVPESGSLKSPHRRTLSFDTSKLNQPGSIVDEGEHSFGRQSDPFTNVTASLPQKFATLPRKKNPFEESSEPWDSSMNLFSKPIEVRKESKREKREKVSLFERVTGKRDSRRPDKLNNGGSDSPCDLKSPSAFSENRQDYFEYESTNPFTAKFRASTIMPSSSFHVNPTSSEDLRKIPDNNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFTNS", "length": 512 }, "evidence": [ { "id": "G3X6N7", "url": "https://omabrowser.org/oma/group/G3X6N7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7L804-1", "protein_name": "Rab11 family-interacting protein 2", "gene_name": "RAB11FIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLIQGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTFSDTSSAIIPSTHMPDANSEFSSGEIQMKSKPKKPFLLGPQRLSSAHSMSDLSGSHMSSEKLKAGTIGQTHLLGHQLDSFGTVPESGSLKSPHRRTLSFDTSKMNQPDSIVDEGELCFGRQNDPFTNVTASLPQKFATLPRKKNPFEESSETWDSSMNLFSKPIEIRKENKREKREKVSLFERVTGKKDSRRSDKLNNGGSDSPCDLKSPNAFSENRQDYFDYESTNPFTAKFRASNIMPSSSFHMSPTSNEDLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFSNS", "length": 512 }, "evidence": [ { "id": "G3X6N7", "url": "https://omabrowser.org/oma/group/G3X6N7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "TRAM-dependent toll-like receptor 4 signaling pathway", "id": "GO:0035669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035669", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035773", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "G3X6N7", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6N7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 511, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6N7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6N7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 120, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X6N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6N7" }, { "id": "PS51511", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51511" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FIP-RBD", "eco_id": "ECO_0000259", "start_pos": 436, "end_pos": 498, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6P1-1", "uniprot_ac": "G3X6P1", "uniprot_id": "G3X6P1_BOVIN", "mass": { "chemical_mass": 54042.0, "monoisotopic_mass": 54042.0 }, "refseq": { "ac": "NP_001180132", "name": "carbohydrate sulfotransferase 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180132" }, "gene_names": [ { "name": "CHST7", "type": "recommended", "evidence": [ { "id": "G3X6P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ] }, { "name": "CHST7", "type": "synonym", "evidence": [ { "id": "NP_001180132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180132" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "G3X6P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6P1/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "G3X6P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6P1/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate sulfotransferase 7", "type": "synonym", "evidence": [ { "id": "NP_001180132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180132" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHST7", "url": "https://www.uniprot.org/uniprotkb/G3X6P1", "locus": { "chromosome": "X", "start_pos": 84990092, "end_pos": 84889050, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007654", "url": "https://www.ensembl.org/id/ENSBTAG00000007654" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007654", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007654", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540357", "url": "https://www.ncbi.nlm.nih.gov/gene/540357", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540357", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540357", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKMNKVI", "url": "https://omabrowser.org/oma/group/WKMNKVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6P1", "url": "https://www.orthodb.org/?gene=G3X6P1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10704:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10704:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001180132", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6P1-1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGRRRRRREYCKFALLLVLYTLVLLIIPSVLDGGRDGDKGARHCPGLQRSLGVWSLEAAAAGEREQGAEARPAAEGGAGGSPRSPGNLNSAIGEAASREKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLQLYAPPGDPAARPPDAANLTTASLFRWRTNKVICSPPLCPGGPRARAEVGLVEDAACERSCPPVALRALEAECHKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDRFHRVLLSHGVGARPGGASRALPAAPRADFFLTGALEVICEAWMRDLLFARGAPTWLRRRYLRLRYEDLVQQPRAQLRRLQRFAGLRALAALDAFALNMTRGAAYGADRPFHLSARDAREAVHAWRERLSREQVRQVEAACAPAMRLLAYPRSGEDGDVEPPEDEETQPETEADSAT", "length": 486, "header": "tr|G3X6P1-1|G3X6P1_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=CHST7 PE=3 SV=1 CANONICAL=G3X6P1-1" }, "isoforms": [ { "isoform_ac": "G3X6P1-1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1/entry", "sequence": { "sequence": "MKGRRRRRREYCKFALLLVLYTLVLLIIPSVLDGGRDGDKGARHCPGLQRSLGVWSLEAAAAGEREQGAEARPAAEGGAGGSPRSPGNLNSAIGEAASREKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLQLYAPPGDPAARPPDAANLTTASLFRWRTNKVICSPPLCPGGPRARAEVGLVEDAACERSCPPVALRALEAECHKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDRFHRVLLSHGVGARPGGASRALPAAPRADFFLTGALEVICEAWMRDLLFARGAPTWLRRRYLRLRYEDLVQQPRAQLRRLQRFAGLRALAALDAFALNMTRGAAYGADRPFHLSARDAREAVHAWRERLSREQVRQVEAACAPAMRLLAYPRSGEDGDVEPPEDEETQPETEADSAT", "length": 486, "header": "tr|G3X6P1-1|G3X6P1_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=CHST7 PE=3 SV=1 CANONICAL=G3X6P1-1" }, "locus": { "chromosome": "X", "start_pos": 84917928, "end_pos": 84917217, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092066.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092066.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086236.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:540357", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540357", "resource": "KEGG Pathway" }, { "id": "R-BTA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P3Q1-1", "protein_name": "Carbohydrate sulfotransferase 7", "gene_name": "CHST7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKGRRRWCWRGEHRRLALLLALYTLLLLLLVPYVLDYGARRARADEEPLLRRCPSLEEALSEWGWEQRPPPPGDDEEEEEAAAAAGNGSGAGKRHIYLHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDALSLQGALRDMLRALFRCDFSVLRLYAAPAGPRDPLGAAPPAANLTTAGIFGWRTNKVICSAPLCPAAPRPRREIGLVDGAACEQRCPPRALRELEAECRKYPVVVIKDVRLLELGALLPLLREPGLNLRVVQLFRDPRAVHNSRLKAKQALLRESIQVLRSRHRAEPRGPPRPQQPPLPPGLGLLGAGRAPGQHRAEFFLGGALEVICQAWLRDLLLARRNPAALRRRYTQLRYEDLVREPRAQLRRLLRFAGLPVPPAMEAFVVNMTRGAAYSSERPFLISARDAREAVHAWRERLSRQQVRQVEAACGEAMSLLAYPLSAGERR", "length": 464 }, "evidence": [ { "id": "G3X6P1", "url": "https://omabrowser.org/oma/group/G3X6P1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A480YBV2-1", "protein_name": "Sulfotransferase", "gene_name": "CHST7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKGRRRRRREYCKFALLLVLYTLVLLLVPSVLDGGRDGDKGAGHCPGLQRSLGVWSLEAAAAGEREQGAKARPAADGGAGVSPRSPLNLQGAVGEAVSREKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLQLYAPPGDPAARAPDAANLTTAALFGWRTNKVICSPPLCPGAPRARAEVGLVEDAACERSCPPVALQALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDRFHRVLLAHGVGARPGAPSRALPAAPRADFFLTGALEVICEAWLRDLLFARGAPAWLQRRYLWLRYEDLVRQPRAQLRRLQRFAGLRALSALDAFALNMTRGAAYGADRPFHLSARDAREAVHAWRERLSREQVRQVEAACAPAMRLLAYPRSGEDGDAEPSEDEETPLEMEADGAT", "length": 486 }, "evidence": [ { "id": "G3X6P1", "url": "https://omabrowser.org/oma/group/G3X6P1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QE68-1", "protein_name": "Sulfotransferase", "gene_name": "chst7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKRRLQKKYIILILGYSVALLLIPYVLDYRSKSPHIKDGYQQQKCPDLESTIALWSSIRSANSTEAEDSGNRSQSRTHIYLHATWRTGSSFLGELFNQHPDVFYLYEPMWNMWQALYPGDAGSLQGAVRDMMNSLFRCDFSVLKLYAGSSNVSTSFIFGWKTNKVICSEPLCNAYKKHEIGLVQGDVCSKCQPKDLRELEKECKKYPVMVIKDVRVLDLAVLVPLMRDPAINLQIVQLFRDPRAVHNSRLKSKLALVKESIQVLRSKKQSEKYKRLLVPSNRVHRAENYVSSAMELICDNWLNDMSLVLNAPPWVKRNYIRVKYEDLVLKPVDELQRLYRFANLTLSPAMEKFVMNMTRGRGYSSDKPFLISSRDAKEAIFAWRERLNVEQVKQVEAYCSEVMRQLDYQKRNMDKT", "length": 416 }, "evidence": [ { "id": "G3X6P1", "url": "https://omabrowser.org/oma/group/G3X6P1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6XQG8-1", "protein_name": "Carbohydrate sulfotransferase 7", "gene_name": "Chst7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGRRRRRREYCKFTLLLALYTLLLLLVPSVLDSGSEQDKGGRDCPGLQRSLGVWSLEAAAAGEREQGAEVRFQAEGNPDRSPRPQGNLSAIRESVTQEKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGNAESLQGALRDMLRSLFRCDFSVLRLYAQPGDPAERAPDSANLTTAMLFRWRTNKVICSPPLCPAAPRARADVGLVEDKACESTCPPVPLRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRHGLLRESIQVLRTRQRGDRFQRVLLAHGVGARPGGQSRALPSAPRADFFLTSALEVICEAWLRDLLFTRGAPTWLRRRYLRLRYEDLVWQPQVQLRRLLRFSGLRTLAALDAFAFNMTRGSAYGADRPFHLSARDAREAVHAWRERLSQEQVRQVEAACDPAMRLLAYPRSGDERDVKTVRKGETPLETNANWAT", "length": 485 }, "evidence": [ { "id": "G3X6P1", "url": "https://omabrowser.org/oma/group/G3X6P1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EP78-1", "protein_name": "Carbohydrate sulfotransferase 7", "gene_name": "Chst7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGRRRRRREYCKFTLLLALYTLLLLLVPSVLDSHSEQDKGRNCPGLQRSLGVWSLEAAAAGEREQGAEVRSLAEGNPDRSPGSPGNLSAVGEAVTQEKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLRLYAQPGDPGERAPDSANLTTAMLFRWRTNKVICSPPLCPAAPRARADVGLVEDKACESTCPPVSLRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDHFHRVLLAHGVDARPGGQARALPSAPRADFFLTSALEVICEAWLRDLLFTRGAPAWLRRRYLRLRYEDLVWQPQAQLRRLLRFSGLRTLAALDAFAFNMTRGSAYGADRPFHLSARDAREAVHAWRERLSQEQVRQVETACAPAMRLLAYPRSGDERDRKTVREGETPLETKANWAV", "length": 484 }, "evidence": [ { "id": "G3X6P1", "url": "https://omabrowser.org/oma/group/G3X6P1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NS84-1", "protein_name": "Carbohydrate sulfotransferase 7", "gene_name": "CHST7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGRRRRRREYCKFALLLVLYTLVLLLVPSVLDGGRDGDKGAEHCPGLQRSLGVWSLEAAAAGEREQGAEARAAEEGGANQSPRFPSNLSGAVGEAVSREKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLRLYAPPGDPAARAPDTANLTTAALFRWRTNKVICSPPLCPGAPRARAEVGLVEDTACERSCPPVAIRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDRFHRVLLAHGVGARPGGQSRALPAAPRADFFLTGALEVICEAWLRDLLFARGAPAWLRRRYLRLRYEDLVRQPRAQLRRLLRFSGLRALAALDAFALNMTRGAAYGADRPFHLSARDAREAVHAWRERLSREQVRQVEAACAPAMRLLAYPRSGEEGDAEQPREGETPLEMDADGAT", "length": 486 }, "evidence": [ { "id": "G3X6P1", "url": "https://omabrowser.org/oma/group/G3X6P1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetylglucosamine 6-O-sulfotransferase activity", "id": "GO:0001517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001517", "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "pmid": "" }, { "name": "chondroitin 6-sulfotransferase activity", "id": "GO:0008459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008459", "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "pmid": "" }, { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "G3X6P1", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-2018682", "name": "CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X6P1-1" ], "evidence": [ { "id": "R-BTA-2018682", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2018682" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "G3X6P1", "gene_name": "CHST7", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "G3X6P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6P1" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 270, "end_pos": 455, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6X0-1", "uniprot_ac": "G3X6X0", "uniprot_id": "G3X6X0_BOVIN", "mass": { "chemical_mass": 35218.0, "monoisotopic_mass": 35218.0 }, "refseq": { "ac": "NP_001376706", "name": "olfactory receptor family 1 subfamily I member 3", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376706" }, "gene_names": [ { "name": "OR1I3", "type": "recommended", "evidence": [ { "id": "G3X6X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6X0" } ] }, { "name": "OR1I3", "type": "synonym", "evidence": [ { "id": "NP_001376706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376706" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X6X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6X0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 1 subfamily I member 3", "type": "synonym", "evidence": [ { "id": "NP_001376706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376706" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376706" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X6X0", "url": "https://www.uniprot.org/uniprotkb/G3X6X0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6X0", "url": "https://www.uniprot.org/uniprotkb/G3X6X0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1I3", "url": "https://www.uniprot.org/uniprotkb/G3X6X0", "locus": { "chromosome": "7", "start_pos": 8056664, "end_pos": 8057614, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000067975", "url": "https://www.ensembl.org/id/ENSBTAG00000067975" } ] } } ], "crossref": [ { "id": "G3X6X0", "url": "https://alphafold.ebi.ac.uk/entry/G3X6X0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011496", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011496", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506533", "url": "https://www.ncbi.nlm.nih.gov/gene/506533", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506533", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506533", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376706", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X6X0", "url": "https://www.uniprot.org/uniprotkb/G3X6X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6X0-1", "url": "https://www.uniprot.org/uniprotkb/G3X6X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQENQTAVSEFLLLGLSEKPEHQIFLFGLFLPMYLVTIFGNLLIILAIITDLHLHTPMYFFLSNLSLIDIFFSSTTVPKMLVNLWTQSKAIPFAGCLAQMYAFHLFGTMDSFLLAVMAIDRFMAIVHPLHYLAIMSPRVCGLLVVGSWLITNLQSIVHTSLMAQLTFCAASETPHFFCDLMPLLKLSCSDTHTNELVIFAFGIVMGISPLVCKVFSYTCIFRTIFRIPSALGKWKAFSTCGSHLTVVTLFYGTIFAVYLQPASPTSSQKDKAAALMYAVIIPMLNPFIYSLRNKDMKAALRKLGGKVAPISPRAE", "length": 316, "header": "tr|G3X6X0-1|G3X6X0_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1I3 PE=3 SV=3 CANONICAL=G3X6X0-1" }, "isoforms": [ { "isoform_ac": "G3X6X0-1", "url": "https://www.uniprot.org/uniprotkb/G3X6X0/entry", "sequence": { "sequence": "MEQENQTAVSEFLLLGLSEKPEHQIFLFGLFLPMYLVTIFGNLLIILAIITDLHLHTPMYFFLSNLSLIDIFFSSTTVPKMLVNLWTQSKAIPFAGCLAQMYAFHLFGTMDSFLLAVMAIDRFMAIVHPLHYLAIMSPRVCGLLVVGSWLITNLQSIVHTSLMAQLTFCAASETPHFFCDLMPLLKLSCSDTHTNELVIFAFGIVMGISPLVCKVFSYTCIFRTIFRIPSALGKWKAFSTCGSHLTVVTLFYGTIFAVYLQPASPTSSQKDKAAALMYAVIIPMLNPFIYSLRNKDMKAALRKLGGKVAPISPRAE", "length": 316, "header": "tr|G3X6X0-1|G3X6X0_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1I3 PE=3 SV=3 CANONICAL=G3X6X0-1" }, "locus": { "chromosome": "7", "start_pos": 8057614, "end_pos": 8056667, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015278.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015278.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015278.7", "url": "https://www.ensembl.org/id/ENSBTAP00000015278.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:506533", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506533", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3X6X0", "url": "https://www.uniprot.org/uniprotkb/G3X6X0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3X6X0", "url": "https://www.uniprot.org/uniprotkb/G3X6X0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X6X0", "url": "https://www.uniprot.org/uniprotkb/G3X6X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3X6X0", "url": "https://www.uniprot.org/uniprotkb/G3X6X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6X0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6X0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6X0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6X0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6X4-1", "uniprot_ac": "G3X6X4", "uniprot_id": "G3X6X4_BOVIN", "mass": { "chemical_mass": 47339.0, "monoisotopic_mass": 47339.0 }, "refseq": {}, "gene_names": [ { "name": "AADAC", "type": "recommended", "evidence": [ { "id": "G3X6X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6X4" } ] } ], "protein_names": [ { "name": "Arylacetamide deacetylase (esterase)", "type": "synonym", "evidence": [ { "id": "G3X6X4", "database": "UniProtKB", "url": 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR017157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PKHMARW", "url": "https://omabrowser.org/oma/group/PKHMARW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6X4", "url": "https://www.orthodb.org/?gene=G3X6X4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X6X4", "url": "https://www.uniprot.org/uniprotkb/G3X6X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6X4-1", "url": "https://www.uniprot.org/uniprotkb/G3X6X4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSNTVLLKKQNSYNMRKKYFGFLILGVLLAGYIYVPLPDNVEEPWKIMLLNTFLKTSSYLALFGEILGLNHFMKSMALFSRIQGFPPTSDENIIVKDTTFNDIPVRIYVPQQKTKSLRRGLFYIHGGGWCFGSNDYYSYDLLSRWTAERLDAVVISTNYRLAPKYHFPVQFEDVYTALKWFLDPQNLESYGVDPGRIGISGDSAGGNLAAAVAQQLLEDPDVKIKLKVQTLIYPALQNFDFDLPSYRENAHYPVLSKSLMVRFWSEYFTTDRSLKKAMLSNQHIPLESSNLFKFVNWSSLLPEKFKKGHIYKTPTHGSSELAKKYPGILDVKASPLLADDSKLRGLPLTYVITCQYDVLRDDGLMYVTRLQKSGVQVIHNHVEGAFHGTLAFLFTKVGYRAANQYINWLHENL", "length": 414, "header": "tr|G3X6X4-1|G3X6X4_BOVIN Isoform 1 of Arylacetamide deacetylase (esterase) OS=Bos taurus OX=9913 GN=AADAC PE=3 SV=2 CANONICAL=G3X6X4-1" }, "isoforms": [ { "isoform_ac": "G3X6X4-1", "url": "https://www.uniprot.org/uniprotkb/G3X6X4/entry", "sequence": { "sequence": "MLSNTVLLKKQNSYNMRKKYFGFLILGVLLAGYIYVPLPDNVEEPWKIMLLNTFLKTSSYLALFGEILGLNHFMKSMALFSRIQGFPPTSDENIIVKDTTFNDIPVRIYVPQQKTKSLRRGLFYIHGGGWCFGSNDYYSYDLLSRWTAERLDAVVISTNYRLAPKYHFPVQFEDVYTALKWFLDPQNLESYGVDPGRIGISGDSAGGNLAAAVAQQLLEDPDVKIKLKVQTLIYPALQNFDFDLPSYRENAHYPVLSKSLMVRFWSEYFTTDRSLKKAMLSNQHIPLESSNLFKFVNWSSLLPEKFKKGHIYKTPTHGSSELAKKYPGILDVKASPLLADDSKLRGLPLTYVITCQYDVLRDDGLMYVTRLQKSGVQVIHNHVEGAFHGTLAFLFTKVGYRAANQYINWLHENL", "length": 414, "header": "tr|G3X6X4-1|G3X6X4_BOVIN Isoform 1 of Arylacetamide deacetylase (esterase) OS=Bos taurus OX=9913 GN=AADAC PE=3 SV=2 CANONICAL=G3X6X4-1" }, "locus": { "chromosome": "1", "start_pos": 116050044, "end_pos": 116033675, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015373.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015373.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015373.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015373.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X9N3-1", "protein_name": "Arylacetamide deacetylase", "gene_name": "AADAC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAKLLCLCIAFTLVAYYIYSPIPENVEQPWKLMLVSTVFRTLGHVAEAAERLGLANYMDVLMLFSTAEHVAPTSDENVTVTDTELSGVAVRLFLPKKPADGLRRAVLYFHGGGWCVGDAGMKGYDFLARRTSSQLNAVVVSVNYRLAPKYHFPVQFEDVYSVSKFFLQSRVLSQYGVDPTRVCVAGDSAGGNLAAAVAQKLLEDSEVTTKLKAQALIYPALQTLDLNLPSYHQNADMPVLSKSLMVRFWSEYFTSDPSLREAITSNRHVPAQWGHLFQFVNWSTLLPDRMKKGHVYTGPVFGSPALAKKYPGFLDRRAAPLLAAEAQLRGLPPTYILTCEHDVLRDDGVMYATRLKAAGVPVTHEHAEDGFHWAAFHPFPLLCHSNGLVTACAIIFSHSCCLVSARSLPLVPGAPQAAEEQWAEPACVAVVESAHCIPAAWLRVSTARP", "length": 450 }, "evidence": [ { "id": "G3X6X4", "url": "https://omabrowser.org/oma/group/G3X6X4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P22760-1", "protein_name": "Arylacetamide deacetylase", "gene_name": "AADAC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL", "length": 399 }, "evidence": [ { "id": "G3X6X4", "url": "https://omabrowser.org/oma/group/G3X6X4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99PG0-1", "protein_name": "Arylacetamide deacetylase", "gene_name": "Aadac", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKTISLLISVVLVAYYLYIPLPDAIEEPWKVVWETAFVKIGTDLASFGELLGISHFMETIQLLMSFQEVPPTSDEHVTVMETAFDSVPVRIYIPKRKSMALRRGLFYIHGGGWCLGSAAHFSYDTLSRWTAHKLDAVVVSTDYGLAPKHHFPRQFEDVYRSLRWFLQEDVLEKYGVDPRRVGVSGDSAGGNLAAAVTQQLIQDPDVKIKLKVQALIYPALQALDTNVPSQQEGSHFPVLTRSLMVRFWSEYFTTDRGLEKAMLLNQHVPMESSHLLQFVNWSSLLPERYKKSPVYKNPTPGSSELAQKYPGFIDVKACPLLANDNILHHLPKTYIITCQYDVLRDDGLMYVKRLQNVGVHVTHHHVEDGFHGTFSFPGLKLSERMKNQYLSWLIKNL", "length": 398 }, "evidence": [ { "id": "G3X6X4", "url": "https://omabrowser.org/oma/group/G3X6X4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QZH8-1", "protein_name": "Arylacetamide deacetylase", "gene_name": "Aadac", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRTIFLLISVVLVAYYIYIPLPDDIEEPWKIILGNTLLKLGGDLASFGELLGLNHFMDTVQLFMRFQVVPPTSDENVTVMETDFNSVPVRIYIPKRKSTTLRRGLFFIHGGGWCLGSAAYFMYDTLSRRTAHRLDAVVVSTDYGLAPKYHFPKQFEDVYHSLRWFLQEDILEKYGVDPRRVGVSGDSAGGNLTAAVTQQILQDPDVKIKLKVQALIYPALQALDMNVPSQQENSQYPLLTRSLLIRFWSEYFTTDRDLEKAMLLNQHVPVEFSHLLQFVNWSSLLPQRYKKGYFYKTPTPGSLELAQKYPGFTDVKACPLLANDSILHHLPMTYIITCQYDVLRDDGLMYVKRLQNTGVHVTHHHIEDGFHGALTLPGLKITYRMQNQYLNWLHKNL", "length": 398 }, "evidence": [ { "id": "G3X6X4", "url": "https://omabrowser.org/oma/group/G3X6X4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of triglyceride catabolic process", "id": "GO:0010898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010898", "evidence": [ { "database": "UniProtKB", "id": "G3X6X4", "url": "https://www.uniprot.org/uniprotkb/G3X6X4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "G3X6X4", "url": "https://www.uniprot.org/uniprotkb/G3X6X4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "G3X6X4", "url": "https://www.uniprot.org/uniprotkb/G3X6X4" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "G3X6X4", "url": "https://www.uniprot.org/uniprotkb/G3X6X4" } ], "pmid": "" }, { "name": "deacetylase activity", "id": "GO:0019213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019213", "evidence": [ { "database": "UniProtKB", "id": "G3X6X4", "url": "https://www.uniprot.org/uniprotkb/G3X6X4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6X4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 414, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6X4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6X4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6X4" }, { "id": "PF07859", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha/beta hydrolase fold-3", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 280, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 297, "end_pos": 299 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6X9-1", "uniprot_ac": "G3X6X9", "uniprot_id": "G3X6X9_BOVIN", "mass": { "chemical_mass": 46357.0, "monoisotopic_mass": 46357.0 }, "refseq": { "ac": "NP_001179462", "name": "xaa-Arg dipeptidase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179462" }, "gene_names": [ { "name": "PM20D2", "type": "recommended", "evidence": [ { "id": "G3X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6X9" } ] }, { "name": "PM20D2", "type": "synonym", "evidence": [ { "id": "NP_001179462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179462" } ] } ], "protein_names": [ { "name": "Xaa-Arg dipeptidase", "type": "recommended", "evidence": [ { "id": "G3X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6X9/entry#names_and_taxonomy" } ] }, { "name": "xaa-Arg dipeptidase", "type": "synonym", "evidence": [ { "id": "NP_001179462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179462" } ] } ], "function": [ { "annotation": "Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus. Postulated to function in a metabolite repair mechanism by eliminating alternate dipeptide by-products formed during carnosine synthesis.", "evidence": [ { "database": "UniProtKB", "id": "G3X6X9", "url": "https://www.uniprot.org/uniprotkb/G3X6X9#function" }, { "database": "UniProtKB", "id": "ARBA00059388", "url": "https://www.uniprot.org/uniprotkb/ARBA00059388#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6X9", "url": "https://www.uniprot.org/uniprotkb/G3X6X9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PM20D2", "url": "https://www.uniprot.org/uniprotkb/G3X6X9", "locus": { "chromosome": "9", "start_pos": 60957093, "end_pos": 60971257, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011667", "url": "https://www.ensembl.org/id/ENSBTAG00000011667" } ] } } ], "crossref": [ { "id": "G3X6X9", "url": "https://alphafold.ebi.ac.uk/entry/G3X6X9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011667", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011667", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05672", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05672", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "521179", "url": "https://www.ncbi.nlm.nih.gov/gene/521179", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521179", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521179", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRSCAKT", "url": "https://omabrowser.org/oma/group/HRSCAKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6X9", "url": "https://www.orthodb.org/?gene=G3X6X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR30575", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR30575", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR30575:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR30575:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "59608", "url": "https://www.rhea-db.org/rhea/59608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59612", "url": "https://www.rhea-db.org/rhea/59612", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59620", "url": "https://www.rhea-db.org/rhea/59620", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59624", "url": "https://www.rhea-db.org/rhea/59624", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "59628", "url": "https://www.rhea-db.org/rhea/59628", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X6X9", "url": "https://www.uniprot.org/uniprotkb/G3X6X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6X9-1", "url": "https://www.uniprot.org/uniprotkb/G3X6X9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPGEERPVEGGACASVSDLELLKLRAAECVDAAAERLGALSRAIWSEPELAYEEHHAHGVLTRFFQSETPAGSWAVQPHYQLATAFRAEWGSPGGWAAPRPLHLGFLCEYDALPGIGHACGHNLIAEVGAAAALGVKGALESLAGLPLPVKVIVLGTPAEEDGGGKIDLIEAGAFKNLDVVFMAHPSQENAAYLPDVAEHDVTVKYYGKASHAAAYPWEGLNALDAAVLAYNNLSVLRQQLKPTWRVHGIIKNGGVKPNIIPSYSELIYYFRAPSMKELPVLTKKAEDCFRAAALATGCTVEINGGAHDYYNVLPNKSLWKAYVENGKKLGIDFISEDAMFSGPSGSTDFGNVSFVVPGIHPYFYIGSNALNHTEQYTEAAGSQEAQFYTLRTAKALAMTALDVIFKPELLARIREDFRLKLEEEKF", "length": 428, "header": "tr|G3X6X9-1|G3X6X9_BOVIN Isoform 1 of Xaa-Arg dipeptidase OS=Bos taurus OX=9913 GN=PM20D2 PE=3 SV=1 CANONICAL=G3X6X9-1" }, "isoforms": [ { "isoform_ac": "G3X6X9-1", "url": "https://www.uniprot.org/uniprotkb/G3X6X9/entry", "sequence": { "sequence": "MRPGEERPVEGGACASVSDLELLKLRAAECVDAAAERLGALSRAIWSEPELAYEEHHAHGVLTRFFQSETPAGSWAVQPHYQLATAFRAEWGSPGGWAAPRPLHLGFLCEYDALPGIGHACGHNLIAEVGAAAALGVKGALESLAGLPLPVKVIVLGTPAEEDGGGKIDLIEAGAFKNLDVVFMAHPSQENAAYLPDVAEHDVTVKYYGKASHAAAYPWEGLNALDAAVLAYNNLSVLRQQLKPTWRVHGIIKNGGVKPNIIPSYSELIYYFRAPSMKELPVLTKKAEDCFRAAALATGCTVEINGGAHDYYNVLPNKSLWKAYVENGKKLGIDFISEDAMFSGPSGSTDFGNVSFVVPGIHPYFYIGSNALNHTEQYTEAAGSQEAQFYTLRTAKALAMTALDVIFKPELLARIREDFRLKLEEEKF", "length": 428, "header": "tr|G3X6X9-1|G3X6X9_BOVIN Isoform 1 of Xaa-Arg dipeptidase OS=Bos taurus OX=9913 GN=PM20D2 PE=3 SV=1 CANONICAL=G3X6X9-1" }, "locus": { "chromosome": "9", "start_pos": 60971066, "end_pos": 60958097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015493.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015493.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015493.3", "url": "https://www.ensembl.org/id/ENSBTAP00000015493.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521179", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521179", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KG59-1", "protein_name": "Xaa-Arg dipeptidase", "gene_name": "Pm20d2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPVVERPAEPGTSSAAELELLKRRAAERIDEAAERLGALSRAIWSAPELAYEEHRAHGELTRFFECEPPAASWAVQPHFGLPTAFRAEWAPPESAAGPRALQVAFLCEYDALPALGHACGHNLIAEVGVAAALGLRAALESIAAPPPVKVIVLGTPAEEDGGGKIDLIEAGAFENLDVVFMAHPSQENAAYLPDVAEHDVTVKYYGKASHAAAYPWEGVNALDAAVLAYTNLSVLRQQMKPTWRVHGIIKNGGVKPNIIPSYSELVYYFRAPSMKELQVLTKKAEDCFRAAALATGCTVDIESEAHDYYNVIPNKTLCSAYTENGKKLGMEFISEDAVLNGPSGSTDFGNVSFVVPGIHPYFYIGTDALNHTEQYTEAAGSQAAQLYTLRTAKALAMTALDVIFKPALLEGVRKEFKCKLQEEQLLNTAA", "length": 431 }, "evidence": [ { "id": "G3X6X9", "url": "https://omabrowser.org/oma/group/G3X6X9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AAB5-1", "protein_name": "Xaa-Arg dipeptidase", "gene_name": "Pm20d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPVVERPAERCTSSATELELLKQRAAERIDEAAERLGALSRAIWSAPELAYEEHRAHGELTRFFEREPPAASWAVQPHFGLPTAFRAEWAPPEAAAGPGALQLAFLCEYDALPALGHACGHNLIAEVGAAAALGLRAALESIAAPPPVKVIVLGTPAEEEGGGKIDLIKAGAFENLDVVFMAHPSQENAAYLPDVAEHDVTVKYYGKASHAAAYPWEGVNALDAAVLAYNNLSALRQQMKPTWRVHGIIKNGGVKPNIIPSYSELLYYFRAPSMKELHVLTKKAEDSFRAAALATGCTVEIKSEAHDYYNVIPNKTLCSAYMENGKKLGVEFISEDAVLNGPSGSTDFGNVSFVVPGIHPYFYIGTDALNHTEEYTEAAGSQAAQWYTLRTAKALAMTALDVIFKPQLLEGIRKEFKSKLQEEQLLNTPA", "length": 431 }, "evidence": [ { "id": "G3X6X9", "url": "https://omabrowser.org/oma/group/G3X6X9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S0E1-1", "protein_name": "Xaa-Arg dipeptidase", "gene_name": "PM20D2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPRRGLSEPDVFLGSGFLLAAEGAEHVSGDTLEAGPAAWERVSRELWRQPERTPSACAGAVGREEGGIQPAVPRSADRLAAVGTMRPEEERPVEGGACVGVSQLELLKLRAADCIDEAAERLGALSRAIWNKPELAYEEHHAHGVLTRFFESEPPAGSWAVQPHYQLATAFRAEWGPPPRGLAATRPLHLGFLCEYDALPDIGHACGHNLIAEVGAAAALGVKGCLESLPGPPLPVKVVVLGTPAEEDGGGKIDLIEAGAFTNLDVVFMAHPSQENAAYLPDAAEHDLIVKYYGKASHAAAYPWEGLNALDAAVLAYNNLSVLRQQMKPTWRVHGIIKNGGVKPNIIPSYSELIYYLRAPSVKELPVLTKKAEDCFRAAALATGCTVEIKAGAHDYYNVLPNKSLWKAYVENGKKLGIDFISEDAVFNGPSGSTDFGNVTFVVPGIHPYFYIGSQALNHTEQYTEAAGSQEAQFYTLRTAKALAMTALDVIFKPELLEKIREDFKLKLREEEFLNTVE", "length": 519 }, "evidence": [ { "id": "G3X6X9", "url": "https://omabrowser.org/oma/group/G3X6X9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8IYS1-1", "protein_name": "Xaa-Arg dipeptidase", "gene_name": "PM20D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPGGERPVEGGACNGRSELELLKLRSAECIDEAAERLGALSRAIWSQPELAYEEHHAHRVLTHFFEREPPAASWAVQPHYQLPTAFRAEWEPPEARAPSATPRPLHLGFLCEYDALPGIGHACGHNLIAEVGAAAALGVRGALEGLPRPPPPVKVVVLGTPAEEDGGGKIDLIEAGAFTNLDVVFMAHPSQENAAYLPDMAEHDVTVKYYGKASHSASYPWEGLNALDAAVLAYNNLSVFRQQMKPTWRVHGIIKNGGVKPNIIPSYSELIYYFRAPSMKELQVLTKKAEDCFRAAALASGCTVEIKGGAHDYYNVLPNKSLWKAYMENGRKLGIEFISEDTMLNGPSGSTDFGNVSFVVPGIHPYFHIGSNALNHTEQYTEAAGSQEAQFYTLRTAKALAMTALDVIFKPELLEGIREDFKLKLQEEQFVNAVE", "length": 436 }, "evidence": [ { "id": "G3X6X9", "url": "https://omabrowser.org/oma/group/G3X6X9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X6X9", "url": "https://www.uniprot.org/uniprotkb/G3X6X9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { 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This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Required for ribosome biogenesis and telomere maintenance. 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"https://www.ensembl.org/id/ENSBTAG00000013045" } ] } } ], "crossref": [ { "id": "G3X717", "url": "https://alphafold.ebi.ac.uk/entry/G3X717", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02572", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02572", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004521", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004521", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23127:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23127:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01472", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01472", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01509", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01509", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "47036", "url": "https://www.rhea-db.org/rhea/47036", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X717", "url": "https://www.uniprot.org/uniprotkb/G3X717", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X717-1", "url": "https://www.uniprot.org/uniprotkb/G3X717-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VLILPKKHKKKKERKSLPEEAVAEIQHAEEFLIKPESRVAQLDTSQWPLLLKNFDKLNVRTTHYTPLPCGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWMQEYVDYSNSAKKDVPPKAVKATPVVAEVVKTPKRKRESESEDTSPAAPQVVKKEKKKKKKEKAKAAAEKPGAGDSDSTKKKKKKKIKAEMVSE", "length": 501, "header": "tr|G3X717-1|G3X717_BOVIN Isoform 1 of H/ACA ribonucleoprotein complex subunit DKC1 OS=Bos taurus OX=9913 GN=DKC1 PE=1 SV=1 CANONICAL=G3X717-1" }, "isoforms": [ { "isoform_ac": "G3X717-1", "url": "https://www.uniprot.org/uniprotkb/G3X717/entry", "sequence": { "sequence": "VLILPKKHKKKKERKSLPEEAVAEIQHAEEFLIKPESRVAQLDTSQWPLLLKNFDKLNVRTTHYTPLPCGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWMQEYVDYSNSAKKDVPPKAVKATPVVAEVVKTPKRKRESESEDTSPAAPQVVKKEKKKKKKEKAKAAAEKPGAGDSDSTKKKKKKKIKAEMVSE", "length": 501, "header": "tr|G3X717-1|G3X717_BOVIN Isoform 1 of H/ACA ribonucleoprotein complex subunit DKC1 OS=Bos taurus OX=9913 GN=DKC1 PE=1 SV=1 CANONICAL=G3X717-1" }, "locus": { "chromosome": "X", "start_pos": 36222159, "end_pos": 36211778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017339.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017339.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017339.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017339.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 403, "start_aa": "Thr", "end_pos": 403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr403", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3X717", "url": "https://www.uniprot.org/uniprotkb/G3X717" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "G3X717", "url": "https://www.uniprot.org/uniprotkb/G3X717" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G3X717", "url": "https://www.uniprot.org/uniprotkb/G3X717" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "G3X717", "url": "https://www.uniprot.org/uniprotkb/G3X717" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA pseudouridine synthesis", "id": "GO:0031118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031118", "evidence": [ { "database": "UniProtKB", "id": "G3X717", "url": "https://www.uniprot.org/uniprotkb/G3X717" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "47036", "name": "", "equation": "uridine in 5S rRNA = pseudouridine in 5S rRNA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5E9Z1-1" ], "evidence": [ { "id": "47036", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47036" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q5E9Z1", "gene_name": "RPUSD4", "activity": [ { "ec_number": "5.4.99.-", "activity": "", "evidence": [ { "id": "Q5E9Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Z1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X717", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X717" }, { "id": "SM01136", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01136" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dyskerin-like", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 101, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X717", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X717" }, { "id": "SM00359", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00359" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PUA", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 366, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 403 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X743-1", "uniprot_ac": "G3X743", "uniprot_id": "G3X743_BOVIN", "mass": { "chemical_mass": 72212.0, "monoisotopic_mass": 72212.0 }, "refseq": {}, "gene_names": [ { "name": "RNPEP", "type": "recommended", "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743" } ] } ], "protein_names": [ { "name": "Aminopeptidase B", "type": "recommended", "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743/entry#names_and_taxonomy" } ] }, { "name": "3.4.11.6", "type": "synonym", "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743/entry#names_and_taxonomy" } ] }, { "name": "Arginine aminopeptidase", "type": "synonym", "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743/entry#names_and_taxonomy" } ] }, { "name": "Arginyl aminopeptidase", "type": "synonym", "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4).", "evidence": [ { "database": "UniProtKB", "id": "G3X743", "url": "https://www.uniprot.org/uniprotkb/G3X743#function" }, { "database": "UniProtKB", "id": "ARBA00058544", "url": "https://www.uniprot.org/uniprotkb/ARBA00058544#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X743", "url": "https://www.uniprot.org/uniprotkb/G3X743" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RNPEP", "url": "https://www.uniprot.org/uniprotkb/G3X743", "locus": { "chromosome": "16", "start_pos": 80509632, "end_pos": 80522913, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013726", "url": "https://www.ensembl.org/id/ENSBTAG00000013726" } ] } } ], "crossref": [ { "id": "G3X743", "url": "https://alphafold.ebi.ac.uk/entry/G3X743", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013726", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013726", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09599", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09599", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45726", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45726", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45726:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45726:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09127", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09127", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X743", "url": "https://www.uniprot.org/uniprotkb/G3X743", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X743-1", "url": "https://www.uniprot.org/uniprotkb/G3X743-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGEPKAGGRALRAAQVDDVASASNFRAFELLHLHLDLRAEFGPPGPGPGSRGLSGSAVLDLRCRAPGGATELRLDSHPCVDVTAAALRRGRPEPGRPEPEPEPLPVCTQPFSHYGQALCLRFSQPCAAGECLQVRITYRVGEGPGVCWLAPEQTAGRKKPFVYTQGQAVLNRAFFPCFDTPAVKCRYSALLEVPDGFTAVMSADAWEERGPNKFFFRMSQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYDGVIEEFLATGEKLFGPYVWGRYDVLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEIAHSWFGNLVTNANWGEFWLNEGFTMYAQRRISSVLFGPAYTCLEAATGRALLRQHMDVTGEDHPLNKLRVRIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQGQFDDFLKAYVDEFKFQSILADDFLDFFLDSFPELKKQRVDSIPAGLEFDRWLDTPGWPPYLPDLSPGDSLMRPAEELAQLWAAEELDPRAINAMPTSAWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIVLKNDHQEDFWKVKEFLHSQGKQKYTLPLYHAMMAGSKAAQTLAKETFAATAPQLHSNVVHYVQQIVEPLGR", "length": 649, "header": "tr|G3X743-1|G3X743_BOVIN Isoform 1 of Aminopeptidase B OS=Bos taurus OX=9913 GN=RNPEP PE=3 SV=3 CANONICAL=G3X743-1" }, "isoforms": [ { "isoform_ac": "G3X743-1", "url": "https://www.uniprot.org/uniprotkb/G3X743/entry", "sequence": { "sequence": "MAAGEPKAGGRALRAAQVDDVASASNFRAFELLHLHLDLRAEFGPPGPGPGSRGLSGSAVLDLRCRAPGGATELRLDSHPCVDVTAAALRRGRPEPGRPEPEPEPLPVCTQPFSHYGQALCLRFSQPCAAGECLQVRITYRVGEGPGVCWLAPEQTAGRKKPFVYTQGQAVLNRAFFPCFDTPAVKCRYSALLEVPDGFTAVMSADAWEERGPNKFFFRMSQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYDGVIEEFLATGEKLFGPYVWGRYDVLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEIAHSWFGNLVTNANWGEFWLNEGFTMYAQRRISSVLFGPAYTCLEAATGRALLRQHMDVTGEDHPLNKLRVRIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQGQFDDFLKAYVDEFKFQSILADDFLDFFLDSFPELKKQRVDSIPAGLEFDRWLDTPGWPPYLPDLSPGDSLMRPAEELAQLWAAEELDPRAINAMPTSAWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIVLKNDHQEDFWKVKEFLHSQGKQKYTLPLYHAMMAGSKAAQTLAKETFAATAPQLHSNVVHYVQQIVEPLGR", "length": 649, "header": "tr|G3X743-1|G3X743_BOVIN Isoform 1 of Aminopeptidase B OS=Bos taurus OX=9913 GN=RNPEP PE=3 SV=3 CANONICAL=G3X743-1" }, "locus": { "chromosome": "16", "start_pos": 80522875, "end_pos": 80509966, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018242.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018242.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018242.7", "url": "https://www.ensembl.org/id/ENSBTAP00000018242.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3X743", "url": "https://www.uniprot.org/uniprotkb/G3X743" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3X743", "url": "https://www.uniprot.org/uniprotkb/G3X743" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X743", "url": "https://www.uniprot.org/uniprotkb/G3X743" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "G3X743", "url": "https://www.uniprot.org/uniprotkb/G3X743" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X743-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 649, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X743-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X743" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743" }, { "id": "SM01263", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01263" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal", "eco_id": "ECO_0000259", "start_pos": 499, "end_pos": 644, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743" }, { "id": "PIRSR634015-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634015-3" } ], "binding_site_uniprot": 323, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 323, "end_pos": 323, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743" }, { "id": "PIRSR634015-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634015-3" } ], "binding_site_uniprot": 327, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 327, "end_pos": 327, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X743", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X743" }, { "id": "PIRSR634015-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634015-3" } ], "binding_site_uniprot": 346, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 346, "end_pos": 346, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.11.6", "ec_name": "Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys.", "evidence": [ { "id": "3.4.11.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.11.6" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X749-1", "uniprot_ac": "G3X749", "uniprot_id": "G3X749_BOVIN", "mass": { "chemical_mass": 62421.0, "monoisotopic_mass": 62421.0 }, "refseq": { "ac": "XP_024842680", "name": "LOW QUALITY PROTEIN: zinc finger protein 503", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842680" }, "gene_names": [ { "name": "ZNF503", "type": "recommended", "evidence": [ { "id": "G3X749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X749" } ] }, { "name": "ZNF503", "type": "synonym", "evidence": [ { "id": "XP_024842680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842680" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: zinc finger protein 503", "type": "synonym", "evidence": [ { "id": "XP_024842680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842680" } ] }, { "name": "Zinc finger protein 503", "type": "synonym", "evidence": [ { "id": "G3X749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X749/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X749", "url": "https://www.uniprot.org/uniprotkb/G3X749" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF503", "url": "https://www.uniprot.org/uniprotkb/G3X749", "locus": { "chromosome": "28", "start_pos": 31133122, "end_pos": 31135985, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014506", "url": "https://www.ensembl.org/id/ENSBTAG00000014506" } ] } } ], "crossref": [ { "id": "G3X749", "url": "https://alphafold.ebi.ac.uk/entry/G3X749", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014506", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014506", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "789846", "url": "https://www.ncbi.nlm.nih.gov/gene/789846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789846", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X749", "url": "https://www.orthodb.org/?gene=G3X749", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12522:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12522:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024842680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842680", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X749", "url": "https://www.uniprot.org/uniprotkb/G3X749", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X749-1", "url": "https://www.uniprot.org/uniprotkb/G3X749-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTAPSLSALRSSKHSGGGGGSADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGTGGAGGGAGGDKDAKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSAEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLPSAGGGPDGKDDKKDPEAGGGGGGTKGSGGSSAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSGSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ", "length": 644, "header": "tr|G3X749-1|G3X749_BOVIN Isoform 1 of Zinc finger protein 503 OS=Bos taurus OX=9913 GN=ZNF503 PE=3 SV=3 CANONICAL=G3X749-1" }, "isoforms": [ { "isoform_ac": "G3X749-1", "url": "https://www.uniprot.org/uniprotkb/G3X749/entry", "sequence": { "sequence": "MSTAPSLSALRSSKHSGGGGGSADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGTGGAGGGAGGDKDAKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSAEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLPSAGGGPDGKDDKKDPEAGGGGGGTKGSGGSSAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSGSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ", "length": 644, "header": "tr|G3X749-1|G3X749_BOVIN Isoform 1 of Zinc finger protein 503 OS=Bos taurus OX=9913 GN=ZNF503 PE=3 SV=3 CANONICAL=G3X749-1" }, "locus": { "chromosome": "28", "start_pos": 31135786, "end_pos": 31133125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019284.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019284.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019284.7", "url": "https://www.ensembl.org/id/ENSBTAP00000019284.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 489, "start_aa": "Thr", "end_pos": 489, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr489", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 610, "start_aa": "Thr", "end_pos": 610, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr610", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:789846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789846", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X749", "url": "https://www.uniprot.org/uniprotkb/G3X749" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3X749", "url": "https://www.uniprot.org/uniprotkb/G3X749" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "G3X749", "url": "https://www.uniprot.org/uniprotkb/G3X749" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "G3X749", "url": "https://www.uniprot.org/uniprotkb/G3X749" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "G3X749", "url": 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"Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X756", "url": "https://www.uniprot.org/uniprotkb/G3X756", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X756-1", "url": "https://www.uniprot.org/uniprotkb/G3X756-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRADLPSAVSSSSGGRKSPLRPPAGWNPGRSLTGRSSNPQLFLMRKLGTSVQRSAAPRNTGAAAPRVWFVPDALGIVCASATWVLTLSEGVLLLSAWLLPAQRPAYSAVHGSLFHLLASLALASHARTMFTDPGALPVGAPPAPGLAARCPLCGAVQTPGAHHCGVCQRCIRRAHHHCPWVNNCVGEDNRKFFVLFTLYTALGALHVLLLLSAPALRAYARGEWDLQTPVLLRPSLLFLFVVALNGFLFAGLMFTIQIRSILTDPQSQPGEPGQASAWTNLKAVLGPRPSPAWISPFASGGPRAASGPQAVV", "length": 314, "header": "tr|G3X756-1|G3X756_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3X756-1" }, "isoforms": [ { "isoform_ac": "G3X756-1", "url": "https://www.uniprot.org/uniprotkb/G3X756/entry", "sequence": { "sequence": 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"protein_name": "Palmitoyltransferase", "gene_name": "LOC100771150", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSWVQKRDTSENRTRLETPLQGPKQRCWFVWDPLGIIFAMATWALVLSAAWILVRDLLIPSNNIFYATANGVVFHLLASLALVSHLKSMLTDPGSVPLGNPPGPDTVLYCPLCLSAIPENADHCTVCRRCIRKNDHHCPWVNNCVGEDNQKYFLLFTLYIWLISTHVLLLLSIPVLRSHAQGEQNASSTVYPPKPIFFLLLVALMGFILALVMFCSQMCAIYRDKTTIEMLYQNKHSRGRRSMWANMKAICGPRVSLTWLSPFHAPERYKVSENHGMA", "length": 279 }, "evidence": [ { "id": "G3X756", "url": "https://omabrowser.org/oma/group/G3X756/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2TGI4-1", "protein_name": "Palmitoyltransferase", "gene_name": "Zdhhc25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3X756", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "G3X756", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "G3X756", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "G3X756", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "G3X756", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X756-1", "E1BPA5-1", "F1MVC6-1", "E1B987-1", "E1BJK1-1", "F6R785-1", "A0AAA9TDW4-1", "A0AAA9TVJ9-1", "A0AAA9TM40-1", "E1B6X9-1", "E1BKA0-1", "E1BK60-1", "Q58CU4-1", "A2VDT6-1", "A0AAF6ZH94-1", "A0AAA9RZ07-1", "Q0VC89-1", "E1BLT8-1", 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"url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] } ] }, { "uniprot_ac": "A0A3Q1M794", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] }, { "ec_number": "2.3.1.225", 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"MLRHSVCQFGQKLVRRRPLEPREKSESLLSRCLNTLDLVALGVGSTLGAGVYILAGDVAKDKAGPAIIICFLVASLSSMLSGICYAEFGARVPGSGSAYLYSYVTVGQLCAFITGWNLILSYVIGTASVSRAWSSTFDSLIGDHISQALQGAFSLHVPHFLAEYPDFFALGLVLLLTGILVVGAGESALVNKVFTGLNLLVLSFVIISGIIKGDPHNWKLTEEDYKPNISGSNDSSSSGPLGAGGFVPFGFDGIVQGAATCFYAFVGFDVIATTGEEARNPQRSIPLGIVISLLICFLAYFGVSASLTLMVPYYQIHTGSPLPQAFLHIGWGPASYVVAVGTLCALTSSLLGAMFPMPRVIYSMADDGLLFRGLARIHARTRTPVMATLASGILAGVMALLFELRDLVDLMSIGTLLAYSLVEFSVLVLRYQPDENLSKKKTEEETEMESVVEASPLNTASEVGNSKILKSLCHPASTIPTRTSGQIVYGCALLLVLLLTILSLILSRWPSQVFSGDPVLTTVAVLLLLLITGVSVIIWRQPQSLRPLHFKVPALPVLPLVSIFVNIYLMIQMTSRTWAQFGVWNVIGFIIYFGYGIRHSLENSEQHPAASAFQTLDKNIPGAESS", "length": 626, "header": "tr|G3X758-1|G3X758_BOVIN Isoform 1 of Cationic amino acid transporter C-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC504861 PE=3 SV=3 CANONICAL=G3X758-1" }, "isoforms": [ { "isoform_ac": "G3X758-1", "url": "https://www.uniprot.org/uniprotkb/G3X758/entry", "sequence": { "sequence": "MLRHSVCQFGQKLVRRRPLEPREKSESLLSRCLNTLDLVALGVGSTLGAGVYILAGDVAKDKAGPAIIICFLVASLSSMLSGICYAEFGARVPGSGSAYLYSYVTVGQLCAFITGWNLILSYVIGTASVSRAWSSTFDSLIGDHISQALQGAFSLHVPHFLAEYPDFFALGLVLLLTGILVVGAGESALVNKVFTGLNLLVLSFVIISGIIKGDPHNWKLTEEDYKPNISGSNDSSSSGPLGAGGFVPFGFDGIVQGAATCFYAFVGFDVIATTGEEARNPQRSIPLGIVISLLICFLAYFGVSASLTLMVPYYQIHTGSPLPQAFLHIGWGPASYVVAVGTLCALTSSLLGAMFPMPRVIYSMADDGLLFRGLARIHARTRTPVMATLASGILAGVMALLFELRDLVDLMSIGTLLAYSLVEFSVLVLRYQPDENLSKKKTEEETEMESVVEASPLNTASEVGNSKILKSLCHPASTIPTRTSGQIVYGCALLLVLLLTILSLILSRWPSQVFSGDPVLTTVAVLLLLLITGVSVIIWRQPQSLRPLHFKVPALPVLPLVSIFVNIYLMIQMTSRTWAQFGVWNVIGFIIYFGYGIRHSLENSEQHPAASAFQTLDKNIPGAESS", "length": 626, "header": "tr|G3X758-1|G3X758_BOVIN Isoform 1 of Cationic amino acid transporter C-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC504861 PE=3 SV=3 CANONICAL=G3X758-1" }, "locus": { "chromosome": "18", "start_pos": 60768024, "end_pos": 60762598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020054.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020054.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020054.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020054.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 105, "start_aa": "Thr", "end_pos": 105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr105", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:504861", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504861", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X758", "url": "https://www.uniprot.org/uniprotkb/G3X758" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "G3X758", "url": "https://www.uniprot.org/uniprotkb/G3X758" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32143", "name": "", "equation": "L-arginine(in) = L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32143" } ] }, { "id": "70935", "name": "", "equation": "L-lysine(in) = L-lysine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70935", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70935" } ] }, { "id": "71199", "name": "", "equation": "L-ornithine(in) = L-ornithine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71199", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71199" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X758-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 626, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X758-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X758" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X758" }, { "id": "PF13906", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13906" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cationic amino acid transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 550, "end_pos": 600, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 105 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 436, "end_pos": 438 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X775-1", "uniprot_ac": "G3X775", "uniprot_id": "G3X775_BOVIN", "mass": { "chemical_mass": 34360.0, "monoisotopic_mass": 34360.0 }, "refseq": { "ac": "NP_001376814", "name": "olfactory receptor family 2 subfamily D member 3G", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376814" }, "gene_names": [ { "name": "OR2D3G", "type": "recommended", "evidence": [ { "id": "G3X775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X775" } ] }, { "name": "OR2D3G", "type": "synonym", "evidence": [ { "id": "NP_001376814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376814" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X775", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X775/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2D3", "type": "synonym", "evidence": [ { "id": "NP_001376814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376814" } ] }, { "name": "olfactory receptor family 2 subfamily D member 3G", "type": "synonym", "evidence": [ { "id": "NP_001376814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376814" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376814" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X775", "url": "https://www.uniprot.org/uniprotkb/G3X775#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X775", "url": "https://www.uniprot.org/uniprotkb/G3X775" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2D3G", "url": "https://www.uniprot.org/uniprotkb/G3X775", "locus": { "chromosome": "15", "start_pos": 46015002, "end_pos": 46014079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000056029", "url": "https://www.ensembl.org/id/ENSBTAG00000056029" } ] } } ], "crossref": [ { "id": "G3X775", "url": "https://alphafold.ebi.ac.uk/entry/G3X775", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000055066", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000055066", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511622", "url": "https://www.ncbi.nlm.nih.gov/gene/511622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { 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"Protein" ] } ], "sequence": { "sequence": "MEEGNQTYVTEFVFLGLSQDPHTQVLLFFLFLIIYLLTVLGNLLIIALIHIDSRLHTPMYFFLRNLSFADLCFSTTTVPQVLVHFLVKRKTISFAGCSTQIVVLLLVGCTECALLAVMSYDRYVAVCKPLHYTTIMTHRVCAQLATGSWASGAFVSLVDTTFTLCLPYRENNIINHFFCEPPALLKLASADTYRTEMAIFAMGVAILLAPVSLILVSYWNIISTVIQMQSGEGRLKAFSTCGSHLTVVVLFYGSAIFAYMRPNSKIMNERDKVISVFYSAVTPMLNPIIYSLRNKDVKGALRRVTAK", "length": 307, "header": "tr|G3X775-1|G3X775_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2D3G PE=3 SV=3 CANONICAL=G3X775-1" }, "isoforms": [ { "isoform_ac": "G3X775-1", "url": "https://www.uniprot.org/uniprotkb/G3X775/entry", "sequence": { "sequence": "MEEGNQTYVTEFVFLGLSQDPHTQVLLFFLFLIIYLLTVLGNLLIIALIHIDSRLHTPMYFFLRNLSFADLCFSTTTVPQVLVHFLVKRKTISFAGCSTQIVVLLLVGCTECALLAVMSYDRYVAVCKPLHYTTIMTHRVCAQLATGSWASGAFVSLVDTTFTLCLPYRENNIINHFFCEPPALLKLASADTYRTEMAIFAMGVAILLAPVSLILVSYWNIISTVIQMQSGEGRLKAFSTCGSHLTVVVLFYGSAIFAYMRPNSKIMNERDKVISVFYSAVTPMLNPIIYSLRNKDVKGALRRVTAK", "length": 307, "header": "tr|G3X775-1|G3X775_BOVIN Isoform 1 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response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377581" }, "gene_names": [ { "name": "OR5W2B", "type": "recommended", "evidence": [ { "id": "G3X784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X784" } ] }, { "name": "OR5W2B", "type": "synonym", "evidence": [ { "id": "NP_001377581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377581" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X784/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5W2", "type": "synonym", "evidence": [ { "id": "NP_001377581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377581" } ] }, { "name": "olfactory receptor family 5 subfamily W member 2B", "type": "synonym", "evidence": [ { "id": "NP_001377581", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377581" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377581", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377581" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X784", "url": "https://www.uniprot.org/uniprotkb/G3X784#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X784", "url": "https://www.uniprot.org/uniprotkb/G3X784" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5W2B", "url": "https://www.uniprot.org/uniprotkb/G3X784", "locus": { "chromosome": "15", "start_pos": 78470776, "end_pos": 78471720, "strand": "+", "evidence": 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}, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100140748", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140748", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MERSNCS", "url": "https://omabrowser.org/oma/group/MERSNCS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X784", "url": "https://www.orthodb.org/?gene=G3X784", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377581", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377581", "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR042065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VHMRPYR", "url": "https://omabrowser.org/oma/group/VHMRPYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X796", "url": "https://www.uniprot.org/uniprotkb/G3X796", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X796-1", "url": "https://www.uniprot.org/uniprotkb/G3X796-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKASGGREVGKVVLQERAVAVDEAEGTERRQAHGSVLLRQLPRPAIQATDSCGNHGNSVMPQTYLPFQGLPELMKIPPDNSPTEGYRFHLQLSNVNKDNHQDHMQQDISSCYPLQPSCLYQMQENETDCTAIYSELLMQVRKSQADKKPYNKQKYIRPYVANTMPIRKAPQVTPDPVPERKRTTPINLAYTIRKSRVPYSVHARTYRDRVIHLLALKDYKKHELLVRLQRDGMTEEEMDSLGKILQEVAHLNTQNRSYSLKNCVFKELQKDWPGYSEVDRQTLELVLSRKVHPLLNVTGTDHPQFSTDSSTDEISFHSQEQLYNSADIDYSKNKKVRISHLTTKQQPASSDCLNNTSEISAMGHPPYSESTTNLSSPSLSNIHLPTSNYLQPVYSKCSYSSITEGPETQDPPVDRFSQSSRIFECQQSKHSLQKVTSISVTMKYPKHMEKQHSLTSEEFKYKFTEYKAKRKECSIKILEKQQTDSERQDEGAKPNSSEEVAKVCTPTGKTCSTSELPDFLTSYVTITSSEQRERYEKEFRVDYEEYKALHETLMPFSKIFVYLTSQKEKFPPDSREYEDINKKISLEYQKMKRMNHNYFKEKLRCQYLYNKLAHIRELINNYDQQ", "length": 625, "header": "tr|G3X796-1|G3X796_BOVIN Isoform 1 of OCEL domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3X796-1" }, "isoforms": [ { "isoform_ac": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X799-1", "uniprot_ac": "G3X799", "uniprot_id": "G3X799_BOVIN", "mass": { "chemical_mass": 21028.0, "monoisotopic_mass": 21028.0 }, "refseq": {}, "gene_names": [ { "name": "OBP", "type": "recommended", "evidence": [ { "id": "G3X799", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X799" } ] } ], "protein_names": [ { "name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3X799", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X799/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X799", "url": "https://www.uniprot.org/uniprotkb/G3X799" } ], "common_name": "Bovine", "glygen_name": "Bovine", 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVLFLTLLLGVVCAAQEEEAEQNLSELSGSWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTVDFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVAHNINVDKHGQKTELTGLFVKLNVEDEDLEKFWKLTEDKGIDKKNVVIPLLSSHIKLLFGWLIHPEQL", "length": 183, "header": "tr|G3X799-1|G3X799_BOVIN Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Bos taurus OX=9913 GN=OBP PE=3 SV=2 CANONICAL=G3X799-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2G6/entry", "sequence": { "sequence": "MKVLFLTLLLGVVCAAQEEEAEQNLSELSGSWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTVDFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVAHNINVDKHGQKTELTGLFVKLNVEDEDLEKFWKLTEDKGIDKKNVVNFLENEDHPHPE", "length": 174, "header": "tr|A0A3Q1M2G6-1|A0A3Q1M2G6_BOVIN Computationally mapped isoform of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Bos taurus OX=9913 GN=OBP PE=3 SV=1 CANONICAL=G3X799-1" }, "locus": { "chromosome": "X", "start_pos": 137467063, "end_pos": 137461119, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081223.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081223.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067608.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067608.1" } ] } }, { "isoform_ac": "G3X799-1", "url": "https://www.uniprot.org/uniprotkb/G3X799/entry", "sequence": { "sequence": "MKVLFLTLLLGVVCAAQEEEAEQNLSELSGSWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTVDFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVAHNINVDKHGQKTELTGLFVKLNVEDEDLEKFWKLTEDKGIDKKNVVIPLLSSHIKLLFGWLIHPEQL", "length": 183, "header": "tr|G3X799-1|G3X799_BOVIN Isoform 1 of Lipocalin/cytosolic fatty-acid binding domain-containing protein OS=Bos taurus OX=9913 GN=OBP PE=3 SV=2 CANONICAL=G3X799-1" }, "locus": { "chromosome": "X", "start_pos": 137467063, "end_pos": 137460875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022593.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022593.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022593.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022593.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:785083", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785083", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SG31-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKILLLSLILGLVWATEPQPDQDASQISGDWNTLYVASTNPEKTSENGTLKPYLRSITFENGKSKIIFTFFIKVNGKCRASSAEGRKIAPNVYEIDYSGKNEFHIDHVSKNSMIVYDINVDEEGKKSIITALNGKGKKAEEQDLKKFKELTRKKGIPEENIVNVIETDNCPTQ", "length": 173 }, "evidence": [ { "id": "G3X799", "url": "https://omabrowser.org/oma/group/G3X799/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3X799", "url": "https://www.uniprot.org/uniprotkb/G3X799" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3X799", "url": "https://www.uniprot.org/uniprotkb/G3X799" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "G3X799", "url": "https://www.uniprot.org/uniprotkb/G3X799" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "G3X799", "url": "https://www.uniprot.org/uniprotkb/G3X799" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X799-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 183, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X799-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X799" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X799", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X799" }, { "id": "PF00061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipocalin/cytosolic fatty-acid binding", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 164, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7D3-1", "uniprot_ac": "G3X7D3", "uniprot_id": "G3X7D3_BOVIN", "mass": { "chemical_mass": 24981.0, "monoisotopic_mass": 24981.0 }, "refseq": { "ac": "NP_001179759", "name": "ras-related protein Rab-39A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179759" }, "gene_names": [ { "name": "RAB39A", "type": "recommended", "evidence": [ { "id": "G3X7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D3" } ] }, { "name": "RAB39A", "type": "synonym", "evidence": [ { "id": "NP_001179759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179759" } ] }, { "name": "RAB39", "type": "synonym", "evidence": [ { "id": "NP_001179759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179759" } ] } ], "protein_names": [ { "name": "RAB39, member RAS oncogene family", "type": "synonym", "evidence": [ { "id": "NP_001179759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179759" } ] }, { "name": "RAB39A, member RAS onco family", "type": "synonym", "evidence": [ { "id": "G3X7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D3/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-39A", "type": "synonym", "evidence": [ { "id": "NP_001179759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179759" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7D3", "url": "https://www.uniprot.org/uniprotkb/G3X7D3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAB39A", "url": "https://www.uniprot.org/uniprotkb/G3X7D3", "locus": { "chromosome": "15", "start_pos": 17533945, "end_pos": 17499451, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018246", "url": "https://www.ensembl.org/id/ENSBTAG00000018246" } ] } } ], "crossref": [ { "id": "G3X7D3", "url": "https://alphafold.ebi.ac.uk/entry/G3X7D3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018246", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018246", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04111", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04111", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "541114", "url": "https://www.ncbi.nlm.nih.gov/gene/541114", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541114", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541114", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LGEQCPC", "url": "https://omabrowser.org/oma/group/LGEQCPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7D3", "url": "https://www.orthodb.org/?gene=G3X7D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8873719", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8873719", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X7D3", "url": "https://www.uniprot.org/uniprotkb/G3X7D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7D3-1", "url": "https://www.uniprot.org/uniprotkb/G3X7D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFQIVFLLVGHKCDLASQRQVTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKRGEICIQDGWEGVKSGFVPNTVHSSEEAVKPRKECFC", "length": 217, "header": "tr|G3X7D3-1|G3X7D3_BOVIN Isoform 1 of RAB39A, member RAS onco family OS=Bos taurus OX=9913 GN=RAB39A PE=3 SV=1 CANONICAL=G3X7D3-1" }, "isoforms": [ { "isoform_ac": "G3X7D3-1", "url": "https://www.uniprot.org/uniprotkb/G3X7D3/entry", "sequence": { "sequence": "METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFQIVFLLVGHKCDLASQRQVTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKRGEICIQDGWEGVKSGFVPNTVHSSEEAVKPRKECFC", "length": 217, "header": "tr|G3X7D3-1|G3X7D3_BOVIN Isoform 1 of RAB39A, member RAS onco family OS=Bos taurus OX=9913 GN=RAB39A PE=3 SV=1 CANONICAL=G3X7D3-1" }, "locus": { "chromosome": "15", "start_pos": 17533125, "end_pos": 17499582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024288.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024288.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024288.4", "url": "https://www.ensembl.org/id/ENSBTAP00000024288.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541114", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541114", "resource": "KEGG Pathway" }, { "id": "R-BTA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-BTA-8873719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8873719", "resource": "Reactome", "description": "RAB geranylgeranylation" }, { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5W5-1", "protein_name": "RAB39A, member RAS onco family", "gene_name": "RAB39A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFRIVFLLVGHKCDLASQRQVTREEAERLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKRGEICIQDGWEGVKSGFVPNTVHSSEEAVKPRKECFC", "length": 217 }, "evidence": [ { "id": "G3X7D3", "url": "https://omabrowser.org/oma/group/G3X7D3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7HNP4-1", "protein_name": "Ras-related protein Rab-39A", "gene_name": "Rab39a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFHIIFLLVGHKCDLASQRQVSREEAEKLSTDCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVKSGFVPNTVHSSEEAVKPRRECFC", "length": 217 }, "evidence": [ { "id": "G3X7D3", "url": "https://omabrowser.org/oma/group/G3X7D3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XQV4-1", "protein_name": "RAB39A, member RAS onco family", "gene_name": "RAB39A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPGVGAIGARCRHRPRRSPREKPEAKPGEAGAAMDAAIWIYQFRLIVLGDSTVGKSCLLHRFTEGRFPGPLHSDPTVGVDFFSRLVEIEPGKRVKLQLWDTAGQERFRSITRSYYRNSVGGLLVFDITNRRSFEHVKDWLEEAKMHVQPFQIVFLLVGHKCDLVSQREVTREEAEKLSSDCGMKYIETSAKDATNVEESFTILTRDIYELVKKGEITIQDGWEGVKSGFVPNVVHSSEEAVKPRRQCIC", "length": 249 }, "evidence": [ { "id": "G3X7D3", "url": "https://omabrowser.org/oma/group/G3X7D3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZZP2-1", "protein_name": "small monomeric GTPase", "gene_name": "Rab39a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFQIVFLLVGHKCDLASQRQVSREEAEKLSKDCGMKYIETSAKDATNVEESFTILARDIYELIKKGDICIQDGWEGVKSGFVPNTVHSSEEAVKPRKQCFC", "length": 217 }, "evidence": [ { "id": "G3X7D3", "url": "https://omabrowser.org/oma/group/G3X7D3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14964-1", "protein_name": "Ras-related protein Rab-39A", "gene_name": "RAB39A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMYVQPFRIVFLLVGHKCDLASQRQVTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVKSGFVPNTVHSSEEAVKPRKECFC", "length": 217 }, "evidence": [ { "id": "G3X7D3", "url": "https://omabrowser.org/oma/group/G3X7D3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHD0-1", "protein_name": "Ras-related protein Rab-39A", "gene_name": "Rab39a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLHSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMHVQPFQIVFLLVGHKCDLASQRQVSREEAERLSTDCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVKSGFVPNTVHSSEEAVKPRKECFC", "length": 217 }, "evidence": [ { "id": "G3X7D3", "url": "https://omabrowser.org/oma/group/G3X7D3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W3Q0-1", "protein_name": "Rab39, isoform B", "gene_name": "Rab39", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O00422-1", "protein_name": "Histone deacetylase complex subunit SAP18", "gene_name": "SAP18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFTDVKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPPPSGRMRPY", "length": 153 }, "evidence": [ { "id": "G3X7E1", "url": "https://omabrowser.org/oma/group/G3X7E1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O55128-1", "protein_name": "Histone deacetylase complex subunit SAP18", "gene_name": "Sap18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELTSLVKEVYPEARKKGTHFNFAIVFMDLKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPPNRAPPSSGRMRPY", "length": 153 }, "evidence": [ { "id": 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"Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.", "evidence": [ { "database": "UniProtKB", "id": "G3X7K2", "url": "https://www.uniprot.org/uniprotkb/G3X7K2#function" }, { "database": "UniProtKB", "id": "ARBA00037531", "url": "https://www.uniprot.org/uniprotkb/ARBA00037531#function" }, { "database": "UniProtKB", "id": "F1MS07", "url": "https://www.uniprot.org/uniprotkb/F1MS07#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7K2", "url": "https://www.uniprot.org/uniprotkb/G3X7K2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC788175", "url": "https://www.uniprot.org/uniprotkb/G3X7K2", "locus": {} } ], "crossref": [ { "id": "G3X7K2", "url": "https://alphafold.ebi.ac.uk/entry/G3X7K2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024960", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024960", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788175", "url": "https://www.ncbi.nlm.nih.gov/gene/788175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"G3X7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7L4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.", "evidence": [ { "database": "UniProtKB", "id": "G3X7L4", "url": "https://www.uniprot.org/uniprotkb/G3X7L4#function" }, { "database": "UniProtKB", "id": "RU364016", "url": "https://www.uniprot.org/uniprotkb/RU364016#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7L4", "url": "https://www.uniprot.org/uniprotkb/G3X7L4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "B4GALNT4", "url": "https://www.uniprot.org/uniprotkb/G3X7L4", "locus": { "chromosome": "29", "start_pos": 50896835, "end_pos": 50909430, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024814", "url": "https://www.ensembl.org/id/ENSBTAG00000024814" } ] } } ], "crossref": [ { "id": "G3X7L4", "url": "https://alphafold.ebi.ac.uk/entry/G3X7L4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024814", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024814", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR008428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "20493", "url": "https://www.rhea-db.org/rhea/20493", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X7L4", "url": "https://www.uniprot.org/uniprotkb/G3X7L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7L4-1", "url": "https://www.uniprot.org/uniprotkb/G3X7L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLRPAAAPGSLEPERPGGAGRGNRRQPLHRPPRALGQGQPGVAAAARGRGRWTKGHAGSGDAARSAQEWGAAATPLSSAPGGAGSAAMPWFPVKKIRKQIKLLLLLVLLTCAAWLTYVHLSLVRQGRALRQRLGYGRDGEKLSGVTDGRGVHAALATQRAEDSSESREEEPVSEGRDPGVLFPGGAGRPLVLNLTRQVPVWREEYKGQVNLHVFEDWCGGAVGQLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRLFGFIHPARDGDVQFSVASDDNSEFWLSPNESPAGAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVIGSAHISLYTDESALKMDHVAHVPQSPASHVAGQPLQEEPRADMLRPDPRDAFFLTPRVEPSDLESVLEPCAYAPTYVVKDFPIARYQGLQFVYLSFVYPNDHTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDREEGGEDREEVQRRAFLFLNPDDFLDDEDDGELLDAGLGPTEAPRRQGSRQLPAPAAPSEAPATPAAPTPRRSRALSWAARQLPLFLGRAPPPRPAARPSKVYVTRVRPGLRAPPGAPPLGARGPPRPPLPGVFLRPRPLPRVPLRAPPRPPRARGHRTSSPPATELRAPAPAPATREGREGRARAPGLAAPTADSNSSSEAQPVTSFLSLSQVSRPQLPGEDEEEEGDDDEEGAPGDENASEDSEEAAGLVRGRWREDAIDWQRTFSVGNVDFELLRSDWNDLRCNVSGNLQLPEAEAVDVVAQYMERLNMRHSGRYALLRIVNVEKRRDSARGSRFLLELELQERGGRRLRLSEYVFLRLPGARAGDTEEDRESPEPAAASARPDGRPELCRPLRLAWRQDVMVHFVVPVKNQARWVMQFLADMAALHARTGDSRFSVVLVDFESEDMDVEQALRAARLPRYQYLRRAGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPSILDGIRKHCVEGKLAFAPVVMRLSCGSSPGDPHGYWEVNGFGLFGIYKSDFDRIGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRIRNFYHHFHSKRGMWGARSRKAARKEAPQKEAP", "length": 1124, "header": "tr|G3X7L4-1|G3X7L4_BOVIN Isoform 1 of Beta-1,4-N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=B4GALNT4 PE=3 SV=3 CANONICAL=G3X7L4-1" }, "isoforms": [ { "isoform_ac": "G3X7L4-1", "url": "https://www.uniprot.org/uniprotkb/G3X7L4/entry", "sequence": { "sequence": "MLLRPAAAPGSLEPERPGGAGRGNRRQPLHRPPRALGQGQPGVAAAARGRGRWTKGHAGSGDAARSAQEWGAAATPLSSAPGGAGSAAMPWFPVKKIRKQIKLLLLLVLLTCAAWLTYVHLSLVRQGRALRQRLGYGRDGEKLSGVTDGRGVHAALATQRAEDSSESREEEPVSEGRDPGVLFPGGAGRPLVLNLTRQVPVWREEYKGQVNLHVFEDWCGGAVGQLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRLFGFIHPARDGDVQFSVASDDNSEFWLSPNESPAGAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVIGSAHISLYTDESALKMDHVAHVPQSPASHVAGQPLQEEPRADMLRPDPRDAFFLTPRVEPSDLESVLEPCAYAPTYVVKDFPIARYQGLQFVYLSFVYPNDHTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDREEGGEDREEVQRRAFLFLNPDDFLDDEDDGELLDAGLGPTEAPRRQGSRQLPAPAAPSEAPATPAAPTPRRSRALSWAARQLPLFLGRAPPPRPAARPSKVYVTRVRPGLRAPPGAPPLGARGPPRPPLPGVFLRPRPLPRVPLRAPPRPPRARGHRTSSPPATELRAPAPAPATREGREGRARAPGLAAPTADSNSSSEAQPVTSFLSLSQVSRPQLPGEDEEEEGDDDEEGAPGDENASEDSEEAAGLVRGRWREDAIDWQRTFSVGNVDFELLRSDWNDLRCNVSGNLQLPEAEAVDVVAQYMERLNMRHSGRYALLRIVNVEKRRDSARGSRFLLELELQERGGRRLRLSEYVFLRLPGARAGDTEEDRESPEPAAASARPDGRPELCRPLRLAWRQDVMVHFVVPVKNQARWVMQFLADMAALHARTGDSRFSVVLVDFESEDMDVEQALRAARLPRYQYLRRAGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPSILDGIRKHCVEGKLAFAPVVMRLSCGSSPGDPHGYWEVNGFGLFGIYKSDFDRIGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRIRNFYHHFHSKRGMWGARSRKAARKEAPQKEAP", "length": 1124, "header": "tr|G3X7L4-1|G3X7L4_BOVIN Isoform 1 of Beta-1,4-N-acetylgalactosaminyltransferase OS=Bos taurus OX=9913 GN=B4GALNT4 PE=3 SV=3 CANONICAL=G3X7L4-1" }, "locus": { "chromosome": "29", "start_pos": 50909231, "end_pos": 50897512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034550.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034550.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034440.6", "url": "https://www.ensembl.org/id/ENSBTAP00000034440.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 539, "start_aa": "Thr", "end_pos": 539, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr539", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 562, "start_aa": "Thr", "end_pos": 562, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr562", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 567, "start_aa": "Thr", "end_pos": 567, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr567", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "G3X7L4", "url": "https://www.uniprot.org/uniprotkb/G3X7L4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "acetylgalactosaminyltransferase activity", "id": "GO:0008376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008376", "evidence": [ { "database": "UniProtKB", "id": "G3X7L4", "url": "https://www.uniprot.org/uniprotkb/G3X7L4" } ], "pmid": "" }, { "name": "N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0033842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033842", "evidence": [ { "database": "UniProtKB", "id": "G3X7L4", "url": "https://www.uniprot.org/uniprotkb/G3X7L4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 785, "end_pos": 787, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20493", "name": "", "equation": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N0M7-1", "G3X7L4-1" ], "evidence": [ { "id": "20493", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20493" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1N0M7", "gene_name": "B4GALNT3", "activity": [ { "ec_number": "2.4.1.244", "activity": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "F1N0M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0M7" } ] }, { "ec_number": "2.4.1.244", "activity": "", "evidence": [ { "id": "F1N0M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0M7" } ] } ] }, { "uniprot_ac": "G3X7L4", "gene_name": "B4GALNT4", "activity": [ { "ec_number": "2.4.1.244", "activity": "an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+).", "evidence": [ { "id": "G3X7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7L4" } ] }, { "ec_number": "2.4.1.244", "activity": "", "evidence": [ { "id": "G3X7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7L4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7L4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1124, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7L4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7L4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7L4" }, { "id": "PS51820", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51820" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PA14", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 367, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00017IP", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G00193HL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00230CO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00279YF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00318OS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00372ZO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00470UO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00582VL", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00624KQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00636QL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00645SW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00740UU", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G00743WU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G00805TZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00915XC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00979HB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01158PQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01323LL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01414CL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G01510MQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G01522FD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02057LB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02310VX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02473HY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02670IJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G02872OI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G02915XR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03165SD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G03319HQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03834RX", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G03855LZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G03921DY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G03944IG", "type": "N-linked", "subtype": "Triantennary" }, { 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"MADIDNKEQSELDQDLDDVEEVEEEETGEETKIKAHQLTVQMMQNPQILAALQERLDGLVETPTGYAESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYSVLYQPLFDKRFEIINAIYEPTEEECEWKPGEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDTVQEHDEPILKYLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPQGSDDSDPFSFDGPEIMGCTGCQIDCKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPETGDLDDDSEAILAADFEIGHFLREHIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDCDPKKDQNPAECKQQ", "length": 394, "header": "tr|G3X7M5-1|G3X7M5_BOVIN Isoform 1 of Nucleosome assembly protein 1-like 1 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=G3X7M5-1" }, "isoforms": [ { "isoform_ac": "G3X7M5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7M5/entry", "sequence": { "sequence": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "G3X7M5", "url": "https://www.uniprot.org/uniprotkb/G3X7M5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7M5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 394, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7M5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7M5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 270, "end_pos": 272 }, { "start_pos": 297, "end_pos": 299 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7M6-1", "uniprot_ac": "G3X7M6", "uniprot_id": "G3X7M6_BOVIN", "mass": { "chemical_mass": 35334.0, "monoisotopic_mass": 35334.0 }, "refseq": { "ac": "XP_003587019", "name": "olfactory receptor 51F1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587019" }, "gene_names": [ { "name": "OR51F1", "type": "recommended", "evidence": [ { "id": "G3X7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7M6" } ] }, { "name": "OR51F1", "type": "synonym", "evidence": [ { "id": "XP_003587019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587019" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7M6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 51F1", "type": "synonym", "evidence": [ { "id": "XP_003587019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587019" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X7M6", "url": "https://www.uniprot.org/uniprotkb/G3X7M6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7M6", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507882", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLVIMHT", "url": "https://omabrowser.org/oma/group/FLVIMHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7M6", "url": "https://www.orthodb.org/?gene=G3X7M6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003587019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587019", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X7M6", "url": "https://www.uniprot.org/uniprotkb/G3X7M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7M6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPVQENMEILGNSTSKFPTFLLTGIPGLEFAHAWISIPFCCLYATALSGNSMILFVIITQQSLHKPMYYFLSMLSAADLGLTVSTMSTTLGILWFDANEISLDMCIIQMFFLHGFTCTESGVLVAMAFDRCVAICDPLRYTSILTNYRIIQMGLLMVIRTVVLTVLLLLLLKPLNFCGGNVLSHSYCYHPDVIKLACSDTQANSICGLIDLILTTGVDTPCIVLSYILIIHSVLSISSPQEQHIVFSTCVSHLGAVSIFYIPMISLSLVHRYGRSAPKVVHSMMANMYLLFPPVLNPIIYSVKTKQIRKAILSLLLMK", "length": 319, "header": "tr|G3X7M6-1|G3X7M6_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR51F1 PE=3 SV=1 CANONICAL=G3X7M6-1" }, "isoforms": [ { "isoform_ac": "G3X7M6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7M6/entry", "sequence": { "sequence": "MLPVQENMEILGNSTSKFPTFLLTGIPGLEFAHAWISIPFCCLYATALSGNSMILFVIITQQSLHKPMYYFLSMLSAADLGLTVSTMSTTLGILWFDANEISLDMCIIQMFFLHGFTCTESGVLVAMAFDRCVAICDPLRYTSILTNYRIIQMGLLMVIRTVVLTVLLLLLLKPLNFCGGNVLSHSYCYHPDVIKLACSDTQANSICGLIDLILTTGVDTPCIVLSYILIIHSVLSISSPQEQHIVFSTCVSHLGAVSIFYIPMISLSLVHRYGRSAPKVVHSMMANMYLLFPPVLNPIIYSVKTKQIRKAILSLLLMK", "length": 319, "header": "tr|G3X7M6-1|G3X7M6_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR51F1 PE=3 SV=1 CANONICAL=G3X7M6-1" }, "locus": { "chromosome": "15", "start_pos": 48719894, "end_pos": 48718938, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038666.4", "url": "https://www.ensembl.org/id/ENSBTAT00000038666.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038478.3", "url": 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"MSTGSVSDPEEMELQGLQRGYPVPVSKRPSLRGAERSYVSPSDNSSAEEDDPDGEEERCALGAAGGAGGCKRKRPRVAGGGGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA", "length": 197, "header": "tr|G3X7V5-1|G3X7V5_BOVIN Isoform 1 of Musculin OS=Bos taurus OX=9913 GN=MSC PE=4 SV=1 CANONICAL=G3X7V5-1" }, "isoforms": [ { "isoform_ac": "G3X7V5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7V5/entry", "sequence": { "sequence": "MSTGSVSDPEEMELQGLQRGYPVPVSKRPSLRGAERSYVSPSDNSSAEEDDPDGEEERCALGAAGGAGGCKRKRPRVAGGGGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA", "length": 197, "header": "tr|G3X7V5-1|G3X7V5_BOVIN Isoform 1 of Musculin OS=Bos taurus OX=9913 GN=MSC PE=4 SV=1 CANONICAL=G3X7V5-1" }, "locus": { "chromosome": "14", "start_pos": 35441608, "end_pos": 35440131, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046864.5", "url": "https://www.ensembl.org/id/ENSBTAT00000046864.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044112.3", "url": "https://www.ensembl.org/id/ENSBTAP00000044112.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507407", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507407", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZNI8-1", "protein_name": "Musculin", "gene_name": "Msc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTGSVSDPEDTEMRGLQRVYPAPASKRPPLLRPERSYASPSDNSSAEEEDPDGEEEPGTVGAAGGCKRKRPRGADASGAGGGAGSTGKKALPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLAKNGEPSVVQLFPDNNLADVAIRGLWTPRL", "length": 205 }, "evidence": [ { "id": "G3X7V5", "url": "https://omabrowser.org/oma/group/G3X7V5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RWI0-1", "protein_name": "Musculin", "gene_name": "MSC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTGSVSDPEEMELRGLQRGYPVPASKRLPLRGAERSYISPSDNSSAEEEDPDGEEERCALGAAGGAGGCKRKRPRVAGGGGGGGGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAASRLCGTTA", "length": 201 }, "evidence": [ { "id": "G3X7V5", "url": "https://omabrowser.org/oma/group/G3X7V5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60682-1", "protein_name": "Musculin", "gene_name": "MSC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA", "length": 206 }, "evidence": [ { "id": "G3X7V5", "url": "https://omabrowser.org/oma/group/G3X7V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88940-1", "protein_name": "Musculin", "gene_name": "Msc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTGSVSDPEDSEMRGLQRVYPAPASKRPPLLRMERGYGSPSDISSAEEEDGEEEPGSLGAAGGCKRKRLRGADAGGAGGRAGGAGKKPLPPKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEDSYVHPVNLTWPFVVSGRPDSDSKDVSAANRLCGTSA", "length": 201 }, "evidence": [ { "id": "G3X7V5", "url": "https://omabrowser.org/oma/group/G3X7V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": 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"skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" }, { "name": "branchiomeric skeletal muscle development", "id": "GO:0014707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014707", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" }, { "name": "diaphragm development", "id": "GO:0060539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060539", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3X7V5", "url": "https://www.uniprot.org/uniprotkb/G3X7V5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase 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"monoisotopic_mass": 35618.0 }, "refseq": { "ac": "XP_003586951", "name": "solute carrier family 25 member 32", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586951" }, "gene_names": [ { "name": "SLC25A32", "type": "recommended", "evidence": [ { "id": "G3X7X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7X2" } ] }, { "name": "SLC25A32", "type": "synonym", "evidence": [ { "id": "XP_003586951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586951" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 32", "type": "recommended", "evidence": [ { "id": "G3X7X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7X2/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial FAD transporter", "type": "synonym", "evidence": [ { "id": "G3X7X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7X2/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 25 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"https://www.genome.jp/dbget-bin/www_bget?bta:782162", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TTVWKHE", "url": "https://omabrowser.org/oma/group/TTVWKHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7X2", "url": "https://www.orthodb.org/?gene=G3X7X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196757", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196757", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003586951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586951", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "76535", "url": "https://www.rhea-db.org/rhea/76535", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X7X2", "url": "https://www.uniprot.org/uniprotkb/G3X7X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7X2-1", "url": "https://www.uniprot.org/uniprotkb/G3X7X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGQGQSASGLSAWSSTIFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYKGILHCLTTIWKLDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLISAAEAGAMTLCITNPLWVTKTRLMLQYDSVVNASQRQYKGMFDTLVKIYKYEGVRGLYKGFIPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVIRARLQDQHMFYNGVLDVMTKTWRKEGISGFYKGIAPNLIRVTPACCITFVVYENVSHFLLGLRKDDIN", "length": 317, "header": "tr|G3X7X2-1|G3X7X2_BOVIN Isoform 1 of Solute carrier family 25 member 32 OS=Bos taurus OX=9913 GN=SLC25A32 PE=3 SV=1 CANONICAL=G3X7X2-1" }, "isoforms": [ { "isoform_ac": "G3X7X2-1", "url": "https://www.uniprot.org/uniprotkb/G3X7X2/entry", "sequence": { "sequence": "MTGQGQSASGLSAWSSTIFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYKGILHCLTTIWKLDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLISAAEAGAMTLCITNPLWVTKTRLMLQYDSVVNASQRQYKGMFDTLVKIYKYEGVRGLYKGFIPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVIRARLQDQHMFYNGVLDVMTKTWRKEGISGFYKGIAPNLIRVTPACCITFVVYENVSHFLLGLRKDDIN", "length": 317, "header": "tr|G3X7X2-1|G3X7X2_BOVIN Isoform 1 of Solute carrier family 25 member 32 OS=Bos taurus OX=9913 GN=SLC25A32 PE=3 SV=1 CANONICAL=G3X7X2-1" }, "locus": { "chromosome": "14", "start_pos": 61107691, "end_pos": 61075338, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048106.4", "url": "https://www.ensembl.org/id/ENSBTAT00000048106.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045203.2", "url": "https://www.ensembl.org/id/ENSBTAP00000045203.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 291, "start_aa": "Thr", "end_pos": 291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr291", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:782162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782162", "resource": "KEGG Pathway" }, { "id": "R-BTA-196757", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196757", "resource": "Reactome", "description": "Metabolism of folate and pterines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PZX4-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAAPGAQGHACAVGPPASPVRSVLRHVQLENLAAGLSGGVVSTLVLHPLDLVKIRFAVSDGLELRPKYNGILHCMATVWKREGLRGLYQGVTPNMVGAGASWGLYFFFYNAIKAYKKEGKLESLTATEHLVSAAEAGAMTLCITNPIWVTKTRLVLQYDAGVDPSKRQYTGMSDALIKIYKTEGIRGLYKGFVPGLFGTSHGALQFMAYEDLKQRYNKYRNRVSDTKLNTAEYIMMAAVSKIFAVTATYPYQVVRARLQDQHNRYSGVLDVIRRTWRKEGIHGFYKGIVPNVIRVTPACCITFVVYENVSGFLLGFRKENN", "length": 322 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8D0MB03-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGQGQTASASSAWSSIFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYKGILHCLTTIWKLDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAERLEAAEYLISAAEAGAMTLCITNPLWVTKTRLMLQYEGVVTASQRQYKGMFDALVKIYKYEGVRGLYKGFIPGLFGTSHGALQFMTYELLKLKYNQHINRLPEAQLNTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVLDVITKTWRKEGISGFYKGIAPNLIRVTPACCITFVVYENVSHFLLGLKEKKK", "length": 315 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5Y115-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "Slc25a32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSQGQSAAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLEVRPKYKGILHCLATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQLEALEYLISAAEAGAMTLCITNPLWVTKTRLMLQYGGVVNPSQRQYKGMIDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYEVLKLKYNKHINKLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENCMCLKQQQTPLCLKHKARKSPAEQHSS", "length": 329 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1Z7S4-1", "protein_name": "Mitochondrial folate transporter/carrier", "gene_name": "anon-WO0242455.53", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNPIKAQSTGSPKKFNVFAHVKYEHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVPQYRGLSSAFTTIFRQEGFRGLYKGVTPNVWGSGSSWGLYFMFYNTIKTFIQGGNTTMPLGPTMNMLAAAESGILTLLLTNPIWVVKTRLCLQCDAASSAEYRGMIHALGQIYKEEGIRGLYRGFVPGMLGVSHGAIQFMTYEELKNAYNEYRKLPIDTKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQDHHHRYNGTWDCIKQTWRFEGYRGFYKGLKASLTRVVPACMVTFLVYENVSHFLLARRKRIETKEDASDV", "length": 322 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O22261-1", "protein_name": "Nicotinamide adenine dinucleotide transporter 1, chloroplastic", "gene_name": "NDT1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSANSHPPNSKNVLCNAAAGAAAGVVAATFVCPLDVIKTRFQVHGLPKLGDANIKGSLIVGSLEQIFKREGMRGLYRGLSPTVMALLSNWAIYFTMYDQLKSFLCSNDHKLSVGANVLAASGAGAATTIATNPLWVVKTRLQTQGMRVGIVPYKSTFSALRRIAYEEGIRGLYSGLVPALAGISHVAIQFPTYEMIKVYLAKKGDKSVDNLNARDVAVASSIAKIFASTLTYPHEVVRARLQEQGHHSEKRYSGVRDCIKKVFEKDGFPGFYRGCATNLLRTTPAAVITFTSFEMVHRFLVTHIPSEQSSIL", "length": 312 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P40464-1", "protein_name": "Mitochondrial FAD carrier protein FLX1", "gene_name": "FLX1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVDHQWTPLQKEVISGLSAGSVTTLVVHPLDLLKVRLQLSATSAQKAHYGPFMVIKEIIRSSANSGRSVTNELYRGLSINLFGNAIAWGVYFGLYGVTKELIYKSVAKPGETQLKGVGNDHKMNSLIYLSAGASSGLMTAILTNPIWVIKTRIMSTSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGLVPALFGVSQGALYFAVYDTLKQRKLRRKRENGLDIHLTNLETIEITSLGKMVSVTLVYPFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGLYKGLSANLVRAIPSTCITFCVYENLKHRL", "length": 311 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8BMG8-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "Slc25a32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGQGQSAAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLEVRPKYKGILHCLATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQLEPLEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNKHINRLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFLYDLREKKVS", "length": 316 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2D1-1", "protein_name": "Solute carrier family 25 member 32", "gene_name": "SLC25A32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLDLREKRK", "length": 315 }, "evidence": [ { "id": "G3X7X2", "url": "https://omabrowser.org/oma/group/G3X7X2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3X7X2", "url": "https://www.uniprot.org/uniprotkb/G3X7X2" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "G3X7X2", "url": "https://www.uniprot.org/uniprotkb/G3X7X2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "G3X7X2", "url": "https://www.uniprot.org/uniprotkb/G3X7X2" } ], "pmid": "" }, { "name": "mitochondrial FAD transmembrane transport", "id": "GO:1990548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990548", "evidence": [ { "database": "UniProtKB", "id": "G3X7X2", "url": "https://www.uniprot.org/uniprotkb/G3X7X2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "FAD transmembrane transporter activity", "id": "GO:0015230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015230", "evidence": [ { "database": "UniProtKB", "id": "G3X7X2", "url": "https://www.uniprot.org/uniprotkb/G3X7X2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "76535", "name": "", "equation": "FAD(in) = FAD(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "76535", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/76535" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7X2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 317, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7X2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7X2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 291 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X800-1", "uniprot_ac": "G3X800", "uniprot_id": "G3X800_BOVIN", "mass": { "chemical_mass": 85841.0, "monoisotopic_mass": 85841.0 }, "refseq": { "ac": "XP_059745315", "name": "disintegrin and metalloproteinase domain-containing protein 20-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745315" }, 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"ac": "NP_001376823", "name": "olfactory receptor family 5 subfamily L member 1C", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376823" }, "gene_names": [ { "name": "OR5L1C", "type": "recommended", "evidence": [ { "id": "G3X815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X815" } ] }, { "name": "OR5L1C", "type": "synonym", "evidence": [ { "id": "NP_001376823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376823" } ] }, { "name": "OR5L1", "type": "synonym", "evidence": [ { "id": "NP_001376823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376823" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X815", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X815/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 5 subfamily L member 1C", "type": "synonym", "evidence": [ { "id": "NP_001376823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376823" } ] }, { "name": "olfactory receptor, family 5, subfamily L, member 1", "type": "synonym", "evidence": [ { "id": "NP_001376823", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376823" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376823", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376823" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X815", "url": "https://www.uniprot.org/uniprotkb/G3X815#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X815", "url": "https://www.uniprot.org/uniprotkb/G3X815" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5L1C", "url": "https://www.uniprot.org/uniprotkb/G3X815", "locus": { "chromosome": "16", "start_pos": 504409, "end_pos": 503474, "strand": "-", "evidence": [ { 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"categories": [ "Protein Classification" ] }, { "id": "G3X823", "url": "https://www.orthodb.org/?gene=G3X823", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002697385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697385", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X823-1", "url": "https://www.uniprot.org/uniprotkb/G3X823-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDIRSISGGRPVCPLCKKPFKKENIRPVWQLASLVENIERLKVDRGRQPGEVAQEQADVRLCERHREKLHYYCEDDGKLLCVMCRESREHRPHSAVLVEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQRQCIVAEFEQGHQFLREREQHLLGQLAKLEQELTEGREKFKTRGVGELARLAQVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWIGKPIARVVKKKTGEFSDKLQSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYSGLYQGAYLYPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEDEGDEAEEGEEEEEEEEAGYRDGYDDWETDEDEESLGDEEEEAEEEEEEVLESCLVGVARDSVKRKGDLSLRPEDGVWALRLSSAGIWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLLPFLWLKWPGTRLLLRP", "length": 539, "header": "tr|G3X823-1|G3X823_BOVIN Isoform 1 of Tripartite motif-containing protein 26 OS=Bos taurus OX=9913 GN=LOC785873 PE=3 SV=2 CANONICAL=G3X823-1" }, "isoforms": [ { "isoform_ac": "G3X823-1", "url": "https://www.uniprot.org/uniprotkb/G3X823/entry", "sequence": { "sequence": "MAASAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDIRSISGGRPVCPLCKKPFKKENIRPVWQLASLVENIERLKVDRGRQPGEVAQEQADVRLCERHREKLHYYCEDDGKLLCVMCRESREHRPHSAVLVEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQRQCIVAEFEQGHQFLREREQHLLGQLAKLEQELTEGREKFKTRGVGELARLAQVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWIGKPIARVVKKKTGEFSDKLQSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYSGLYQGAYLYPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEDEGDEAEEGEEEEEEEEAGYRDGYDDWETDEDEESLGDEEEEAEEEEEEVLESCLVGVARDSVKRKGDLSLRPEDGVWALRLSSAGIWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLLPFLWLKWPGTRLLLRP", "length": 539, "header": "tr|G3X823-1|G3X823_BOVIN Isoform 1 of Tripartite motif-containing protein 26 OS=Bos taurus OX=9913 GN=LOC785873 PE=3 SV=2 CANONICAL=G3X823-1" }, "locus": { "chromosome": "23", "start_pos": 28786319, "end_pos": 28777820, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000050226.6", "url": "https://www.ensembl.org/id/ENSBTAT00000050226.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046960.4", "url": "https://www.ensembl.org/id/ENSBTAP00000046960.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:785873", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785873", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2Q9Z7-1", "protein_name": "Tripartite motif-containing protein 26", "gene_name": "TRIM26", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDIHPVSGGRPVCPLCKKPFTKENIRPVWQLASLVENIERLKVDTGRQPGEVAREQQDTRLCERHQEKLHYYCEDDGKLLCVMCRESREHRPHTAVLVEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAELKKLQDQRQRILAAFEQGHQFLWEREQHLLDQLAKLEQEVTEGREKYKTRGVGELARLAQVISELEGKAQQPAAELMQDTRDFLTRYPRKKFWIGKPIARVVKKRTGEFSDKLLSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYSGLYQSSYLHPQQFECEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGAGFGYGDGYDDGADEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTRPEAELFPAQRPRRVGIALDYEGGTVTFTNAESQELIYTFKATFTRRLLPFLWLRWPGTRLLLRP", "length": 544 }, "evidence": [ { "id": "G3X823", "url": "https://omabrowser.org/oma/group/G3X823/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LLS2-1", "protein_name": "Tripartite motif-containing protein 26", "gene_name": "Trim26", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAASAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTGDIRPVSGSRPVCPLCKKPFKKENIRPVWQLASLVENIERLKVDNGRQPGELAREPQDMKLCERHQEKLHYYCEDDGKLLCVMCRESREHRPHTAVLVEKAALPHREKILNHLNTLRRDREKIQGFQAKGEADITAALTKLQEQRQYIVAEFKQGHQFLKKREQHLLDQLATLEQLLTEGREKFKTRGVSELGRLTLVISELEGKARQPAAELMQDACSTQDTKDFANRYPRKKFWIGKAIPHMVKRKAGEFSDKLLSLQRGLRQFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVIYTSHYQSDCLHPQQFDCEPGVLGSKGFTWGKVYWEVELEREGWSEDEEEDGEEEEDGEEEEDDEEAGYGDGYEEWETDEDEESLGEEEEEEEEEEEEVLESCMVGVAKDSMKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAQLFPVLRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLLLRP", "length": 546 }, "evidence": [ { "id": "G3X823", "url": "https://omabrowser.org/oma/group/G3X823/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q12899-1", "protein_name": "Tripartite motif-containing protein 26", "gene_name": "TRIM26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLLLRP", "length": 539 }, "evidence": [ { "id": "G3X823", "url": "https://omabrowser.org/oma/group/G3X823/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99PN3-1", "protein_name": "Tripartite motif-containing protein 26", "gene_name": "Trim26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTSDIRPISGNRPVCPLCKKPFKKENIRPVWQLASLVENIERLKVDNGRQPGELAREPQDMKLCERHQEKLHYYCEDDGKLLCVMCRESREHRPHTAVLVEKAALPHREKILNHLNTLRRDRDKIQGFQAKGEADILAALTKLQEQRQYIVAEFKQGHQFLKKREQHLLDQLATLEQLLTEGREKFKTRGVSELDRLTLVISELEGKARQPAAELMQDVCTTQDTKDFANKYPRKKFWIGKAIPHMVKRKAGEFSDKLLSLQRGLRQFQGKLLRDLEYKTVSVTLDPQSASGYLHLSEDWKCVTYTGQYQSDCLLPQQFDCEPGVLGSKGFTWGKVYWEVELEREGWSEDEEEGEEEEEGEEEEEDEEVGYGDGYEDWETDEEDESLGEEEEEEEEEEEEVQESCMVGVAKDSVKRKGDLSLRPEDGVWALRLSPSGIWANTSPEAQLFPVLRPRRVGIALDYEGGTVTFTNAESQELIYTFTTTFTRRLVPFLWLKWPGARLLLRP", "length": 545 }, "evidence": [ { "id": "G3X823", "url": "https://omabrowser.org/oma/group/G3X823/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "suppression of viral release by host", "id": "GO:0044790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044790", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" }, { "name": "host-mediated suppression of symbiont invasion", "id": "GO:0046597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046597", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "G3X823", "url": "https://www.uniprot.org/uniprotkb/G3X823" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X823-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 539, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X823-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X823" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X823" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 138, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X823" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 539, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X823" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 57, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 473, "end_pos": 475 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X827-1", "uniprot_ac": "G3X827", "uniprot_id": "G3X827_BOVIN", "mass": { "chemical_mass": 35643.0, "monoisotopic_mass": 35643.0 }, "refseq": { "ac": "NP_001377562", "name": "olfactory receptor family 13 subfamily C member 2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377562" }, "gene_names": [ { "name": "OR13C2", "type": "recommended", "evidence": [ { "id": "G3X827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X827" } ] }, { "name": "OR13C2", "type": "synonym", "evidence": [ { "id": "NP_001377562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377562" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X827/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 13C2", "type": "synonym", "evidence": [ { "id": "NP_001377562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377562" } ] }, { "name": "olfactory receptor family 13 subfamily C member 2", "type": "synonym", "evidence": [ { "id": "NP_001377562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377562" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X827", "url": "https://www.uniprot.org/uniprotkb/G3X827#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377562" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X827", "url": "https://www.uniprot.org/uniprotkb/G3X827#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X827", "url": "https://www.uniprot.org/uniprotkb/G3X827" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR13C2", "url": "https://www.uniprot.org/uniprotkb/G3X827", "locus": { "chromosome": "8", "start_pos": 94262676, "end_pos": 94263632, "strand": "+", "evidence": 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receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377555" }, "gene_names": [ { "name": "OR13C8", "type": "recommended", "evidence": [ { "id": "G3X829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X829" } ] }, { "name": "OR13C8", "type": "synonym", "evidence": [ { "id": "NP_001377555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377555" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X829/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 13 subfamily C member 8", "type": "synonym", "evidence": [ { "id": "NP_001377555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377555" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X829", "url": "https://www.uniprot.org/uniprotkb/G3X829#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377555", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377555" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X829", "url": "https://www.uniprot.org/uniprotkb/G3X829#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X829", "url": "https://www.uniprot.org/uniprotkb/G3X829" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR13C8", "url": "https://www.uniprot.org/uniprotkb/G3X829", "locus": { "chromosome": "8", "start_pos": 94433685, "end_pos": 94432723, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000063885", "url": "https://www.ensembl.org/id/ENSBTAG00000063885" } ] } } ], "crossref": [ { "id": "G3X829", "url": "https://alphafold.ebi.ac.uk/entry/G3X829", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049056", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049056", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "789782", "url": "https://www.ncbi.nlm.nih.gov/gene/789782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789782", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789782", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVTGLVD", "url": "https://omabrowser.org/oma/group/WVTGLVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X829", "url": "https://www.orthodb.org/?gene=G3X829", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377555", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377555", "database": "RefSeq", 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"60324", "url": "https://www.rhea-db.org/rhea/60324", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60344", "url": "https://www.rhea-db.org/rhea/60344", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60348", "url": "https://www.rhea-db.org/rhea/60348", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X834-1", "url": "https://www.uniprot.org/uniprotkb/G3X834-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMSPNRSPENSTEGDAGRTEWKPKAKDAFKDISIYFTKEEWAEMGEWEKIRYRNVKRNYEALIAIGFRATQPGFMHHRRQVLKPQVDDTEDSDEEWTPRQQGKPSGMAFRGERSKHQKRLSRGPLNKVSSLKKLPGAAKLLKKSGSKQAQKPVPPPREARTPGKHPRHKVELRRKETKVKRYSVRERKGHVYQEVSEPQDDDYLYCEECQNFFIDSCAAHGPPTFVKDSAVEKGHANRSALTLPPGLSIRPSGIPEAGLGVWNEASDLPLGLHFGPYEGQIIYNEEDSHSGYCWLVTKGRNSYEYVDGKDTSLANWMRYVNCARDDEEQNLVALQYHGQIFYRTCRVVRPGCELLVWYGDEYGEELGIKQDKRGKSKLSAQREPKPKIYPCASCCLSFSSQKFLSQHVQRNHPSQILLRPSIGDHLQPEDPCPGSQNEQQRYSDPHSLSDKPEGREPKERPHPLLKGPKLCIRLKRISTASSYPPKGQMGGSEVHERMTEEPSTSQKLNPEDTGKLFMEAGVSGIVRVKYGEHEQDSKDKSSLITHEKIHTGEKPYVCTECGKSFNWKSDLTKHKRTHSEEKPYACGECGRSFSFKKNLIIHQRTHTGEKPYVCGECGRSFSEKSNLTKHKRTHTGEKPYACGECGQSFSFKKNLITHQRTHTGEKPYVCGECGRSFSEKSRLTTHKRTHTGEKPYVCGDCGQSFSLKSVLITHQRTHTGEKPYVCRECGRSFSVISNLIRHQRTHTGEKPYVCRECEQSFREKSNLVRHQRTHTGEKPYVCMECE", "length": 787, "header": "tr|G3X834-1|G3X834_BOVIN Isoform 1 of Histone-lysine N-methyltransferase PRDM9 OS=Bos taurus OX=9913 GN= PE=3 SV=4 CANONICAL=G3X834-1" }, "isoforms": [ { "isoform_ac": "G3X834-1", "url": "https://www.uniprot.org/uniprotkb/G3X834/entry", "sequence": { "sequence": "MAMSPNRSPENSTEGDAGRTEWKPKAKDAFKDISIYFTKEEWAEMGEWEKIRYRNVKRNYEALIAIGFRATQPGFMHHRRQVLKPQVDDTEDSDEEWTPRQQGKPSGMAFRGERSKHQKRLSRGPLNKVSSLKKLPGAAKLLKKSGSKQAQKPVPPPREARTPGKHPRHKVELRRKETKVKRYSVRERKGHVYQEVSEPQDDDYLYCEECQNFFIDSCAAHGPPTFVKDSAVEKGHANRSALTLPPGLSIRPSGIPEAGLGVWNEASDLPLGLHFGPYEGQIIYNEEDSHSGYCWLVTKGRNSYEYVDGKDTSLANWMRYVNCARDDEEQNLVALQYHGQIFYRTCRVVRPGCELLVWYGDEYGEELGIKQDKRGKSKLSAQREPKPKIYPCASCCLSFSSQKFLSQHVQRNHPSQILLRPSIGDHLQPEDPCPGSQNEQQRYSDPHSLSDKPEGREPKERPHPLLKGPKLCIRLKRISTASSYPPKGQMGGSEVHERMTEEPSTSQKLNPEDTGKLFMEAGVSGIVRVKYGEHEQDSKDKSSLITHEKIHTGEKPYVCTECGKSFNWKSDLTKHKRTHSEEKPYACGECGRSFSFKKNLIIHQRTHTGEKPYVCGECGRSFSEKSNLTKHKRTHTGEKPYACGECGQSFSFKKNLITHQRTHTGEKPYVCGECGRSFSEKSRLTTHKRTHTGEKPYVCGDCGQSFSLKSVLITHQRTHTGEKPYVCRECGRSFSVISNLIRHQRTHTGEKPYVCRECEQSFREKSNLVRHQRTHTGEKPYVCMECE", "length": 787, "header": "tr|G3X834-1|G3X834_BOVIN Isoform 1 of Histone-lysine N-methyltransferase PRDM9 OS=Bos taurus OX=9913 GN= PE=3 SV=4 CANONICAL=G3X834-1" }, "locus": { "chromosome": "X", "start_pos": 133093388, "end_pos": 133083356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056084.5", "url": "https://www.ensembl.org/id/ENSBTAT00000056084.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047652.5", "url": "https://www.ensembl.org/id/ENSBTAP00000047652.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" }, { "id": "R-BTA-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "resource": "Reactome", "description": "PKMTs methylate histone lysines" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" }, { "name": "recombination hotspot binding", "id": "GO:0010844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010844", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" }, { "name": "positive regulation of reciprocal meiotic recombination", "id": "GO:0010845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010845", "evidence": [ { "database": "UniProtKB", "id": "G3X834", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51736", "name": "", "equation": "L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2YDJ8-1", "Q0P585-1", "P0DPE2-1", "A4FV98-1", "E1BI64-1", "A5PK19-1", "A6QP81-1", "E1B906-1", "G3X834-1", "F1MDT8-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1", "A0ABI0NZS0-1" ], "evidence": [ { "id": "51736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51736" } ] }, { "id": "54196", "name": "", "equation": "N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P0DPE2-1", "A4FV98-1", "A5PK19-1", "A6QP81-1", "G3X834-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "54196", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54196" } ] }, { "id": "60260", "name": "", "equation": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MZS3-1", "A0AAA9TB51-1", "Q0P585-1", "G3X834-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "60260", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60260" } ] }, { "id": "60276", "name": "", "equation": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X834-1", "A0A3Q1LVN6-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "60276", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60276" } ] }, { "id": "60324", "name": "", "equation": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MDT8-1", "A0A3S5ZPV5-1", "E1BGA4-1", "G3X834-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "60324", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60324" } ] }, { "id": "60344", "name": "", "equation": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMB9-1", "Q2YDJ8-1", "Q29RP8-1", "A6QPM3-1", "E1B906-1", "G3X834-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "60344", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60344" } ] }, { "id": "60348", "name": "", "equation": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMB9-1", "A0A3Q1M6A7-1", "Q29RP8-1", "E1B906-1", "G3X834-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1" ], "evidence": [ { "id": "60348", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60348" } ] }, { "id": "R-BTA-5244692", "name": "Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BKN0-1", "F1N6Y5-1", "G3X834-1", "A0AAA9TQW6-1", "F1MHA1-1", "E1BLX2-1" ], "evidence": [ { "id": "R-BTA-5244692", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5244692" } ] }, { "id": "R-BTA-975040", "name": "KRAB-ZNF / KAP Interaction", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BJG5-1", "A0A3Q1MPX3-1", "G3X834-1" ], "evidence": [ { "id": "R-BTA-975040", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975040" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LMB9", "gene_name": "KMT5B", "activity": [ { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1LMB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB9" } ] } ] }, { "uniprot_ac": "A0A3Q1LVN6", "gene_name": "PRDM2", "activity": [ { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1LVN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVN6" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0A3Q1LVN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVN6" } ] } ] }, { "uniprot_ac": "A0A3Q1M6A7", "gene_name": "KMT5C", "activity": [ { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1M6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6A7" } ] } ] }, { "uniprot_ac": "A0A3Q1MPX3", "gene_name": "PRDM9", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] } ] }, { "uniprot_ac": "A0A3S5ZPV5", "gene_name": "SMYD5", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] }, { "ec_number": "2.1.1.372", "activity": "L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] }, { "ec_number": "2.1.1.372", "activity": "", "evidence": [ { "id": "A0A3S5ZPV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPV5" } ] } ] }, { "uniprot_ac": "A0AAA9SSU7", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] } ] }, { "uniprot_ac": "A0AAA9TB51", "gene_name": "SMYD3", "activity": [ { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9TB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB51" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0AAA9TB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB51" } ] } ] }, { "uniprot_ac": "A0AAA9TQW6", "gene_name": "KMT2C", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9TQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQW6" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0AAA9TQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQW6" } ] } ] }, { "uniprot_ac": "A0ABI0NZS0", "gene_name": "SETD7", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] } ] }, { "uniprot_ac": "A4FV98", "gene_name": "EEF1AKMT3", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A4FV98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV98" } ] } ] }, { "uniprot_ac": "A5PK19", "gene_name": "METTL13", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A5PK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK19" } ] } ] }, { "uniprot_ac": "A6QP81", "gene_name": "METTL21C", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A6QP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QP81" } ] } ] }, { "uniprot_ac": "A6QPM3", "gene_name": "PRDM6", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A6QPM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPM3" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A6QPM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPM3" } ] } ] }, { "uniprot_ac": "E1B906", "gene_name": "SETD4", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] } ] }, { "uniprot_ac": "E1BGA4", "gene_name": "ASH1L", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.367", "activity": "L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] }, { "ec_number": "2.1.1.367", "activity": "", "evidence": [ { "id": "E1BGA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGA4" } ] } ] }, { "uniprot_ac": "E1BI64", "gene_name": "SETD6", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "E1BI64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI64" } ] } ] }, { "uniprot_ac": "E1BJG5", "gene_name": "TRIM28", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJG5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJG5" } ] } ] }, { "uniprot_ac": "E1BKN0", "gene_name": "KMT2B", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BKN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1BKN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN0" } ] } ] }, { "uniprot_ac": "E1BLX2", "gene_name": "SETD1A", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1BLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ] } ] }, { "uniprot_ac": "F1MDT8", "gene_name": "SETD2", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "F1MDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDT8" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "F1MDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDT8" } ] } ] }, { "uniprot_ac": "F1MHA1", "gene_name": "KMT2A", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1MHA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHA1" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "F1MHA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHA1" } ] } ] }, { "uniprot_ac": "F1MZS3", "gene_name": "SMYD1", "activity": [ { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "F1MZS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZS3" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "F1MZS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZS3" } ] } ] }, { "uniprot_ac": "F1N6Y5", "gene_name": "SETD1B", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1N6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y5" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "F1N6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y5" } ] } ] }, { "uniprot_ac": "G3X834", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "G3X834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X834" } ] }, { "ec_number": "2.1.1.362", "activity": "", 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"MALHVPKALGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHVQEQEVGDGTNFVLVFAGALLELAEELLRLGLSVSEVIEGYEIACKKAPPDLVCCSAKNLQDVDEVLSLLHTSVMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGVHSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKSAEELMNFSKGEENLMDAQVKAIADTGANVIVTGGRVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGAIALPRLNPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEAEVPAVKDMLEAGVLDTYLGKHWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDEDQND", "length": 524, "header": "tr|G3X861-1|G3X861_BOVIN Isoform 1 of T-complex protein 1 subunit theta OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3X861-1" }, "isoforms": [ { "isoform_ac": "G3X861-1", "url": "https://www.uniprot.org/uniprotkb/G3X861/entry", "sequence": { "sequence": "MALHVPKALGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHVQEQEVGDGTNFVLVFAGALLELAEELLRLGLSVSEVIEGYEIACKKAPPDLVCCSAKNLQDVDEVLSLLHTSVMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGVHSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKSAEELMNFSKGEENLMDAQVKAIADTGANVIVTGGRVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGAIALPRLNPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEAEVPAVKDMLEAGVLDTYLGKHWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDEDQND", "length": 524, "header": "tr|G3X861-1|G3X861_BOVIN Isoform 1 of T-complex protein 1 subunit theta OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=G3X861-1" }, "locus": { "chromosome": "7", "start_pos": 13547340, "end_pos": 13545706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054111.4", "url": "https://www.ensembl.org/id/ENSBTAT00000054111.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049380.4", "url": "https://www.ensembl.org/id/ENSBTAP00000049380.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3X861", "url": "https://www.uniprot.org/uniprotkb/G3X861" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "G3X861", "url": "https://www.uniprot.org/uniprotkb/G3X861" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "G3X861", "url": "https://www.uniprot.org/uniprotkb/G3X861" } ], "pmid": "" }, { "name": "ATP-dependent protein folding chaperone", "id": "GO:0140662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140662", "evidence": [ { "database": "UniProtKB", "id": "G3X861", "url": "https://www.uniprot.org/uniprotkb/G3X861" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "G3X861", "url": "https://www.uniprot.org/uniprotkb/G3X861" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "chaperonin-containing T-complex", "id": "GO:0005832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005832", "evidence": [ { "database": "UniProtKB", "id": "G3X861", "url": "https://www.uniprot.org/uniprotkb/G3X861" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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{ "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] } ] }, { "uniprot_ac": "A0A3Q1MR43", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": 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"A0ABI0P204", "gene_name": "LOC112446470", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": 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{ "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": 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"5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + 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{ "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] } ] }, { "uniprot_ac": "Q2NKY8", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] }, { "ec_number": "3.6.4.13", "activity": 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"url": "https://www.uniprot.org/uniprotkb/Q3ZBT1" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q3ZBT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBT1" } ] } ] }, { "uniprot_ac": "Q3ZBV2", "gene_name": "DDX19A", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q3ZBV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBV2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q3ZBV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBV2" } ] } ] }, { "uniprot_ac": "Q3ZC07", "gene_name": "ACTC1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q3ZC07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC07" } ] } ] }, { "uniprot_ac": "Q3ZC91", "gene_name": "SMPDL3A", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "Q3ZC91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC91" } ] }, { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "Q3ZC91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC91" } ] } ] }, { "uniprot_ac": "Q3ZCH0", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q3ZCH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCH0" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q3ZCH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCH0" } ] } ] }, { "uniprot_ac": "Q3ZCI9", "gene_name": "CCT8", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q3ZCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCI9" } ] } ] }, { "uniprot_ac": "Q59HJ6", "gene_name": "LONP1", "activity": [ { "ec_number": "3.4.21.53", "activity": "Hydrolysis of proteins in presence of ATP.", "evidence": [ { "id": "Q59HJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q59HJ6" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q59HJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q59HJ6" } ] }, { "ec_number": "3.4.21.53", "activity": "", "evidence": [ { "id": "Q59HJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q59HJ6" } ] } ] }, { "uniprot_ac": "Q5E9B5", "gene_name": "ACTG2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q5E9B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B5" } ] } ] }, { "uniprot_ac": "Q5E9H5", "gene_name": "BCS1L", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5E9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9H5" } ] } ] }, { "uniprot_ac": "Q5E9M9", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5E9M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9M9" } ] } ] }, { "uniprot_ac": "Q5E9N5", "gene_name": "CLPB", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5E9N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9N5" } ] } ] }, { "uniprot_ac": "Q5W5U4", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5W5U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5W5U4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5W5U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5W5U4" } ] } ] }, { "uniprot_ac": "Q76LV2", "gene_name": "HSP90AA1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q76LV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76LV2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q76LV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76LV2" } ] } ] }, { "uniprot_ac": "Q95M18", "gene_name": "HSP90B1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q95M18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95M18" } ] } ] }, { "uniprot_ac": "Q9TTA5", "gene_name": "SMARCAL1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q9TTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TTA5" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "Q9TTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TTA5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X861-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 524, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X861-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X861" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X862-1", "uniprot_ac": "G3X862", "uniprot_id": "G3X862_BOVIN", "mass": { "chemical_mass": 60666.0, "monoisotopic_mass": 60666.0 }, "refseq": { "ac": "XP_005216983", "name": "putative dimethylaniline monooxygenase [N-oxide-forming] 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216983" }, "gene_names": [ { "name": "LOC517828", "type": "recommended", "evidence": [ { "id": "G3X862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ] }, { "name": "LOC517828", "type": "synonym", "evidence": [ { "id": "XP_005216983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216983" } ] } ], "protein_names": [ { "name": "Flavin-containing monooxygenase", "type": "recommended", "evidence": [ { "id": "G3X862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X862/entry#names_and_taxonomy" } ] }, { "name": "1.-.-.-", "type": "synonym", "evidence": [ { "id": "G3X862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X862/entry#names_and_taxonomy" } ] }, { "name": "putative dimethylaniline monooxygenase [N-oxide-forming] 6", "type": "synonym", "evidence": [ { "id": "XP_005216983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216983" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X862", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC517828", "url": "https://www.uniprot.org/uniprotkb/G3X862", "locus": {} } ], "crossref": [ { "id": "G3X862", "url": "https://alphafold.ebi.ac.uk/entry/G3X862", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047256", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047256", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517828", "url": "https://www.ncbi.nlm.nih.gov/gene/517828", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517828", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517828", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WFGQSHT", "url": "https://omabrowser.org/oma/group/WFGQSHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X862", "url": "https://www.orthodb.org/?gene=G3X862", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005216983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216983", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24468", "url": "https://www.rhea-db.org/rhea/24468", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X862", "url": "https://www.uniprot.org/uniprotkb/G3X862", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X862-1", "url": "https://www.uniprot.org/uniprotkb/G3X862-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKRVAIIGAGVSGLASIRCCLEEGLEPICFERSNEVGGLWEFSDHSEEGRASIYKSVFTNSSKEMMCFPDFPYPDDYPNYMHQSKVQDYIKTFAQKKNLLRYIQFETLVTSIKKCPNFLITGQWEVVSEKDEKQESTIFDAVMICSGHHVYPNLPTDSFPGLDRFQGHYLHSRDYKGPEVYKGKRVLVIGLGNSGCDIAVELSRLVTQVIISTRSGSWVMSRVWDDGYPWDMLYVTRFASFLQNALPSFVSDWLYVKKMNTWFKHENYGLMPLNSTLRKEPVFNDELPSRILCGTITIKPSVKEFTETSAMFEDGTVFEAIDYVIFATGYGYAYPFLEDSIIKSRNNEVTLYKGIFPPFLEKPTLAVIGLVQSLGATIPTADLQARWAVKVFANSCTLPTTNEMMDDIEEKMGKKLKWFGQSQTLQTDYITYMDELGSFIGAKPNIPWLFLTDPQLALEVFFGPCSPYQFRLMGPGKWDGARNAILTQWDRTLKPTRTRAVGEAKRPQPFYNLLKILLFPVLLLAVLLEFY", "length": 532, "header": "tr|G3X862-1|G3X862_BOVIN Isoform 1 of Flavin-containing monooxygenase OS=Bos taurus OX=9913 GN=LOC517828 PE=3 SV=2 CANONICAL=G3X862-1" }, "isoforms": [ { "isoform_ac": "G3X862-1", "url": "https://www.uniprot.org/uniprotkb/G3X862/entry", "sequence": { "sequence": "MVKRVAIIGAGVSGLASIRCCLEEGLEPICFERSNEVGGLWEFSDHSEEGRASIYKSVFTNSSKEMMCFPDFPYPDDYPNYMHQSKVQDYIKTFAQKKNLLRYIQFETLVTSIKKCPNFLITGQWEVVSEKDEKQESTIFDAVMICSGHHVYPNLPTDSFPGLDRFQGHYLHSRDYKGPEVYKGKRVLVIGLGNSGCDIAVELSRLVTQVIISTRSGSWVMSRVWDDGYPWDMLYVTRFASFLQNALPSFVSDWLYVKKMNTWFKHENYGLMPLNSTLRKEPVFNDELPSRILCGTITIKPSVKEFTETSAMFEDGTVFEAIDYVIFATGYGYAYPFLEDSIIKSRNNEVTLYKGIFPPFLEKPTLAVIGLVQSLGATIPTADLQARWAVKVFANSCTLPTTNEMMDDIEEKMGKKLKWFGQSQTLQTDYITYMDELGSFIGAKPNIPWLFLTDPQLALEVFFGPCSPYQFRLMGPGKWDGARNAILTQWDRTLKPTRTRAVGEAKRPQPFYNLLKILLFPVLLLAVLLEFY", "length": 532, "header": "tr|G3X862-1|G3X862_BOVIN Isoform 1 of Flavin-containing monooxygenase OS=Bos taurus OX=9913 GN=LOC517828 PE=3 SV=2 CANONICAL=G3X862-1" }, "locus": { "chromosome": "16", "start_pos": 38724601, "end_pos": 38696229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053708.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053708.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049387.3", "url": "https://www.ensembl.org/id/ENSBTAP00000049387.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:517828", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517828", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QPS5-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "LOC100751286", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKRVAIVGAGVSGLAAIRCCLEEGMEPTCFERSNDVGGLWKFSGHAEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYIKSFAQKKDLLRYIQFETLVSSIKKCSSFLATGQWVVVTEKDGKQDSLLFDAVMICSGHHVYPNMPTDSFPGLEHFQGKCLHSRDYKSPGDFQGKRILVIGLGNSASDIAVELSRLAAQVIISTRSGSWVMSRVWNDGYPWDMVYVTRFATFLRNVLPSFVSDWLYVKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPARILCGTVTIKPSVTKFTESSAVFEDGTVFEAVDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGATIPTADLQARWAAKVFANTCTLPATNEMMHDIDEKMGKKLKWFGQSHTLQTDYITYMDELSAFIGAKPNIPWLFLTDPQLALEVFFGPCSPYQFRLMGPGKWDGARNAILTQWKRTVKPTRTRAVGEAQRPAHLYDLLRMLFFPIILLAVLFTFY", "length": 532 }, "evidence": [ { "id": "G3X862", "url": "https://omabrowser.org/oma/group/G3X862/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LIW4-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLTCRILGLLFQLCVESETQICRKSKALPDIGKSYGGNKMHLQMTMVKKVAIIGAGVSGLASIRCCLEEGLEPICFERSNDVGGLWQFSDHAEEGRASIYQSVFTNSSKEMMCFPDFPYPDDYPNYMHQSKLQEYIKTFAQKKNLLRYIKFETLVSSIKKCPNFLVTGQWEVISEKDGKQESTIFDAVMICSGHHVYPNLPTDSFPGLDRFQGHYFHSRDYKGPEVFKGKRVLVIGLGNSGCDIAVELSRLATQVIISTRSGSWVMSRVWDDGYPWDMVYVTRFASFLRNALPSFVSDWLYVKKMNTWFKHENYGLMPLNGTLRKEPVFNDELPSRILCGTVSIKPSVKEFTETSAVFEDGTMFEAIDFVIFATGYGYAYPFLDDSIIKSRNNEVILFKGIFPPLMEKPTLAVIGLVQSLGAAIPTADLQARWVVKVFTNSCSLPTTDEMMDDTDEKMRKKLKWFGQSQTLQTDYITYMDELGSFIGAKPNIPWLFLTDPQLALEVYFGPCSPYQFRLMGPGKWNGARKAILTQWDRTIKPTRTRAVTEAKRPQPFYNLLKILLFPVLLLAVLLTFY", "length": 578 }, "evidence": [ { "id": "G3X862", "url": "https://omabrowser.org/oma/group/G3X862/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QMN6-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKKVAIVGAGVSGLAAIRCCLEEGLDPICFERSIDVGGLWKFSSHAEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYITSFAQKKGLLRYIQFETLVSSIKKCSSFLTTGQWVVVTEKEGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFRGKCLHSRDYKGPGAFQGKKVLVIGLGNSASDIAVELSRLATQVIISTRSGSWIMSRVWNDGYPWDMVYVTRFTSFLRNILPSFVSDWLYIKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPSRILCGMVTIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNTCVLPTTNEMMDDIDEKMGKKLKWFGQSHTLQTDYITYMDELSSFIGAKPNIPWLFLTDPQLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWKRTVKPTRTRAVGEAQRPRHLYDLLRMLFFPVFFLAVLLTFY", "length": 532 }, "evidence": [ { "id": "G3X862", "url": "https://omabrowser.org/oma/group/G3X862/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R553-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKKVAIVGAGVSGLAAIRCCLEEGLEPICFERSNDVGGLWKFSSHVEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYIKSFAQKKDLLRYIQFETLVSSIKKCSSFLTTGQWVVVTEKDGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFQGKCMHSRDYKGPGDFQGKKVLVIGLGNSASDIAVEVSRLATQVIISTRSGSWVMSRVWNDGYPWDMVYVTRFASFLRNILPSFVSDWLYVKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPARILCGTVSIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLEDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNACVLPTTNEMMDDIDEKMGKKLKWFGQSHTLQTDYITYMDELSSFIGAKPNIPWLFVTDPQLALEVYFGPCSPYQFRLMGPGKWDGARSAILTQWKRTVKPTRTRAVGEAQRPCHLYDLLQMLFFPVFFLAVLLTFY", "length": 532 }, "evidence": [ { "id": "G3X862", "url": "https://omabrowser.org/oma/group/G3X862/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9SXD5-1", "protein_name": "Flavin-containing monooxygenase FMO GS-OX-like 3", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPALSPTRSHHVAVIGAGPAGLVAARELRREGHSVVVFEKQKQVGGTWIYTDEVESDPLSVDPTRSVVHSSVYRSLRINGTRECTGYRDFPFVVRSGVSRDPRRFPSHGEVLAYLKDFAKEFGIEEMVRFETEVVKVSPAAEEGIGKWRIESTEKEKKVRRDEIYDAVVVCNGHYVEPRLAQIPGISSWPGKEMHSHNYRIPEPFRDKVVVLIGNSSSAEDISRDIARVAKEVHVACRSNPADTFIKQTGYNNLWTHSMIESVHEDGSVVYQNGKTISVDIIMHCTGYKYHFPFLDTNGIVTVDDNRVGPLYKDVFPPAFAPWLSFIGIPWQVLPFPMFELQSKWIAGVLSGRIPLPSKEDMMIEIKTFYSTLEVQGIPKRYTHRMGNTQFEYYNWLASQCGCSETEEWRKEMCLANGVRKEAHPETYRDEWDDHHLVSEAYQDFSLYS", "length": 450 }, "evidence": [ { "id": "G3X862", "url": "https://omabrowser.org/oma/group/G3X862/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "G3X862", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "G3X862", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ], "pmid": "" }, { "name": "N,N-dimethylaniline monooxygenase activity", "id": "GO:0004499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004499", "evidence": [ { "database": "UniProtKB", "id": "G3X862", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "G3X862", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "taurine biosynthetic process", "id": "GO:0042412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042412", "evidence": [ { "database": "UniProtKB", "id": "G3X862", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24468", "name": "", "equation": "N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1N427-1", "Q8HYJ9-1", "F1N007-1", "G3X862-1", "G5E5J8-1" ], "evidence": [ { "id": "24468", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24468" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1N427", "gene_name": "FMO1", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "A0A3Q1N427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N427" } ] }, { "ec_number": "1.14.13.148", "activity": "trimethylamine + NADPH + O2 = trimethylamine N-oxide + NADP(+) + H2O.", "evidence": [ { "id": "A0A3Q1N427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N427" } ] }, { "ec_number": "1.14.13.8", "activity": "N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O.", "evidence": [ { "id": "A0A3Q1N427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N427" } ] }, { "ec_number": "1.14.13.148", "activity": "", "evidence": [ { "id": "A0A3Q1N427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N427" } ] }, { "ec_number": "1.14.13.8", "activity": "", "evidence": [ { "id": "A0A3Q1N427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N427" } ] } ] }, { "uniprot_ac": "F1N007", "gene_name": "LOC100140223", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "F1N007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N007" } ] } ] }, { "uniprot_ac": "G3X862", "gene_name": "LOC517828", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "G3X862", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X862" } ] } ] }, { "uniprot_ac": "G5E5J8", "gene_name": "FMO4", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "G5E5J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5J8" } ] } ] }, { "uniprot_ac": "Q8HYJ9", "gene_name": "FMO3", "activity": [ { "ec_number": "1.14.13.148", "activity": "trimethylamine + NADPH + O2 = trimethylamine N-oxide + NADP(+) + H2O.", "evidence": [ { "id": "Q8HYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HYJ9" } ] }, { "ec_number": "1.14.13.8", "activity": "N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O.", "evidence": [ { "id": "Q8HYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HYJ9" } ] }, { "ec_number": "1.14.13.32", "activity": "albendazole + NADPH + O2 + H(+) = albendazole S-oxide + NADP(+) + H2O.", "evidence": [ { "id": "Q8HYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HYJ9" } ] }, { "ec_number": "1.14.13.8", "activity": "", "evidence": [ { "id": "Q8HYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HYJ9" } ] }, { "ec_number": "1.14.13.32", "activity": "", "evidence": [ { "id": "Q8HYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HYJ9" } ] }, { "ec_number": "1.14.13.148", "activity": "", "evidence": [ { "id": "Q8HYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8HYJ9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X862-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 532, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X862-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X862" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 275, "end_pos": 277 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376980" }, "gene_names": [ { "name": "OR51F4", "type": "recommended", "evidence": [ { "id": "G3X864", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X864" } ] }, { "name": "OR51F4", "type": "synonym", "evidence": [ { "id": "NP_001376980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376980" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G3X864", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X864/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 51F1", "type": "synonym", "evidence": [ { "id": "NP_001376980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376980" } ] }, { "name": "olfactory receptor family 51 subfamily F member 4", "type": "synonym", "evidence": [ { "id": "NP_001376980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376980" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376980", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376980" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3X864", "url": "https://www.uniprot.org/uniprotkb/G3X864#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X864", "url": "https://www.uniprot.org/uniprotkb/G3X864" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR51F4", "url": "https://www.uniprot.org/uniprotkb/G3X864", "locus": { "chromosome": "15", "start_pos": 48708761, "end_pos": 48709705, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040017", "url": "https://www.ensembl.org/id/ENSBTAG00000040017" } ] } } ], "crossref": [ { "id": "G3X864", "url": "https://alphafold.ebi.ac.uk/entry/G3X864", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "523090", "url": "https://www.ncbi.nlm.nih.gov/gene/523090", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523090", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523090", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVNAREI", "url": "https://omabrowser.org/oma/group/WVNAREI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X864", "url": "https://www.orthodb.org/?gene=G3X864", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376980", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376980", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X864", "url": "https://www.uniprot.org/uniprotkb/G3X864", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X864-1", "url": "https://www.uniprot.org/uniprotkb/G3X864-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPILHNSTLPTFLLTGIPGLEWAHTWISIPFCCLYLTALSGNTLILFIVLTEPSLHEPMYYFLSMLSTTDIGLCISTLVTVLGIFWVNAREISFNACLSQMFFIHLFTFMESSVLLAMAFDRFVAISNPLRYATILTHTRIAQIGLAVITKGTVILTPLVLLLKHLSFCHSHVLHHSYCFHPDVMKLSCSDTKINSVFGLTAIISTAGVDSVFILLSYVLIIRSVLNIASPEERKKVFSTCISHITAVAIFYIPLISLSFVHRFGKHAPSYVPTLIANVYLLIPPVMNPIIYSIKTKPIQKAMFKLLCFKGTHL", "length": 314, "header": "tr|G3X864-1|G3X864_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR51F4 PE=3 SV=1 CANONICAL=G3X864-1" }, "isoforms": [ { "isoform_ac": "G3X864-1", "url": 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"MTSNLSQPDTVQFCYENVNRSCIKSSYSPASRVILYTVFGFGSLLAIFGNFLVMISVLHFKQLHSPANFLIASLACADFLVGVTVMPFSMVRSVESCWYFGARFCALHSSCDVAFCYSSLFHLCFISIDRYVAVTDPLVYPTKFTVSVSGVCICISWILPIVYSGAVFYTGVSDDGMEELVSALNCIGGCQIVVNQEWVLISVLIFFIPSLIMVILYGKIFIVAKQQALKIENTGSKAESESYKLRVAKRERKAAKTLGVTVVAFMISWLPYTIDILIDAFMGFITPAYIYEICCWGAYYNSAMNPLIYALFYPWFRKAMKVVLTGGLFNDSSSTISLFSELMRALS", "length": 347, "header": "tr|G3X880-1|G3X880_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN=LOC516101 PE=3 SV=2 CANONICAL=G3X880-1" }, "isoforms": [ { "isoform_ac": "G3X880-1", "url": "https://www.uniprot.org/uniprotkb/G3X880/entry", "sequence": { "sequence": 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"MTSNFSQPALQLCYENTNGSCIKTPYSPGPRVILYMVFGFGAVLAVCGNLLVVISVLHFKQLHSPANFLIASLASADFLVGISVMPFSMVRSIESCWYFGDAFCSLHSCCDVAFCYSSALHLCFISVDRYIAVTDPLVYPTKFTVSVSGICISISWILPLVYSSAVFYTGISAKGIESLVSALNCVGGCQIVVNQDWVLIDFLLFFIPTLVMIILYSKIFLVAKQQAVKIETSVSDNRGESSSESHKARVAKRERKAAKTLGVTVVAFMVSWLPYTIDSLVDAFVGFITPAYVYEICCWSAYYNSAMNPLIYAFFYPWFRKAIKLILSGEILKSHSSTMSLFSE", "length": 344 }, "evidence": [ { "id": "G3X880", "url": "https://omabrowser.org/oma/group/G3X880/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923X9-1", "protein_name": "Trace amine-associated receptor 8a", "gene_name": "Taar8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE", "length": 342 }, "evidence": [ { "id": "G3X880", "url": "https://omabrowser.org/oma/group/G3X880/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X880", "url": "https://www.uniprot.org/uniprotkb/G3X880" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": 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"Protein" ] } ], "sequence": { "sequence": "MVNPTVFFNIAVDGEPLGRVSFELFADKVPKTAENVHALRTGEKGFGYKGSCFHRIIPGFMCQGGDSTCHNGTGGKSIYGEKFDDENFILKHTGPGILSTANAGPNTNGSQFFTCTAKTEWLDGKHVVFGKVKEGMDVVEAMERFGSRNGKTSKKITIADCGQI", "length": 164, "header": "tr|G3X8B1-1|G3X8B1_BOVIN Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Bos taurus OX=9913 GN=LOC613401 PE=3 SV=1 CANONICAL=G3X8B1-1" }, "isoforms": [ { "isoform_ac": "G3X8B1-1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1/entry", "sequence": { "sequence": "MVNPTVFFNIAVDGEPLGRVSFELFADKVPKTAENVHALRTGEKGFGYKGSCFHRIIPGFMCQGGDSTCHNGTGGKSIYGEKFDDENFILKHTGPGILSTANAGPNTNGSQFFTCTAKTEWLDGKHVVFGKVKEGMDVVEAMERFGSRNGKTSKKITIADCGQI", "length": 164, "header": "tr|G3X8B1-1|G3X8B1_BOVIN Isoform 1 of Peptidyl-prolyl cis-trans isomerase OS=Bos taurus OX=9913 GN=LOC613401 PE=3 SV=1 CANONICAL=G3X8B1-1" }, "locus": { "chromosome": "4", "start_pos": 31570744, "end_pos": 31570253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3X8B1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X8B1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X8B1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "G3X8B1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "G3X8B1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cyclosporin A binding", "id": "GO:0016018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016018", "evidence": [ { "database": "UniProtKB", "id": "G3X8B1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "G3X8B1", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LI03", "gene_name": "FKBP11", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI03" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI03" } ] } ] }, { "uniprot_ac": "A0A3Q1LJJ1", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LSB7" } ] } ] }, { "uniprot_ac": "A0A3Q1M4A4", "gene_name": "LOC112445968", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1M4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4A4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1M4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4A4" } ] } ] }, { "uniprot_ac": "A0AAA9RV00", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] } ] }, { "uniprot_ac": "A0AAA9TG77", "gene_name": "FKBP15", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9TG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG77" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9TG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG77" } ] } ] }, { "uniprot_ac": "A0AAA9U018", "gene_name": "AIP", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9U018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U018" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9U018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U018" } ] } ] }, { "uniprot_ac": "A0AAF6YJC8", "gene_name": 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[protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A4FV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV72" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A4FV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV72" } ] } ] }, { "uniprot_ac": "A6QPY8", "gene_name": "PIN4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A6QPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPY8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A6QPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPY8" } ] } ] }, { "uniprot_ac": "E1B9G4", "gene_name": "PPIL3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "E1B9G4", "database": 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"id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "late endosomal microautophagy", "id": "GO:0061738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061738", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "positive regulation of viral budding via host ESCRT complex", "id": "GO:1903774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903774", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "intracellular cholesterol transport", "id": "GO:0032367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032367", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "vesicle budding from membrane", "id": "GO:0006900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006900", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "protein targeting to lysosome", "id": "GO:0006622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "regulation of protein localization to plasma membrane", "id": "GO:1903076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903076", "evidence": [ { "database": 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[ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "vacuole organization", "id": "GO:0007033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007033", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "nucleus organization", "id": "GO:0006997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006997", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "vesicle uncoating", "id": "GO:0072319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072319", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0090611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090611", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "viral budding from plasma membrane", "id": "GO:0046761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046761", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": 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"id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "G3X8E2", "url": "https://www.uniprot.org/uniprotkb/G3X8E2" } 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"reactions": [ { "id": "R-BTA-917693", "name": "ESCRT Disassembly", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endosome membrane", "input_participant_list": [], "output_participant_list": [ "R-BTA-917703", "R-BTA-917722", "R-BTA-917736" ], "enzyme_list": [ "Q0VD48-1", "G3X8E2-1" ], "evidence": [ { "id": "R-BTA-917693", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-917693" } ] }, { "id": "R-BTA-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Zan Linsen", "evidence": [ { "database": "RefSeq", "id": "NP_001193598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193598" } ], "reference": [ { "type": "PubMed", "id": "27979739", "url": "https://glygen.org/publication/PubMed/27979739" } ] }, { "title": "Detection of Insertions/Deletions Within SIRT1, SIRT2 and SIRT3 Genes and Their Associations with Body Measurement Traits in Cattle.", "journal": "Biochemical genetics", "date": "2018-12", "authors": "Jin Yunyun, Yang Qing, Gao Jiayang, Tang Qi, Duan Bo, Yu Ting, Qi Xinglei, Liu Jiming, Wang Rongmin, Dang Ruihua, Lei Chuzhao, Chen Hong, Lan Xianyong", "evidence": [ { "database": "RefSeq", "id": "NP_001193598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193598" } ], "reference": [ { "type": "PubMed", "id": "29869077", "url": "https://glygen.org/publication/PubMed/29869077" } ] }, { "title": "Sirtuin 3 mitigates oxidative-stress-induced apoptosis in bovine mammary epithelial cells.", "journal": "Journal of dairy science", "date": "2023-10", "authors": "Liu Lei, Lu Ouyang, Li Dan, Tian Yuan, Liu Ziling, Wen Yanqiong, Peng Tao, Song Yuxiang, Du Xiliang, Wang Zhe, Liu Guowen, Li Xinwei", "evidence": [ { "database": "RefSeq", "id": "NP_001193598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193598" } ], "reference": [ { "type": "PubMed", "id": "37730176", "url": "https://glygen.org/publication/PubMed/37730176" } ] } ], "pathway": [ { "id": "bta:614027", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614027", "resource": "KEGG Pathway" }, { "id": "R-BTA-2151201", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2151201", "resource": "Reactome", "description": "Transcriptional activation of mitochondrial biogenesis" }, { "id": "R-BTA-9617629", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9617629", "resource": "Reactome", "description": "Regulation of FOXO transcriptional activity by acetylation" }, { "id": "R-BTA-9841251", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841251", "resource": "Reactome", "description": "Mitochondrial unfolded protein response (UPRmt)" }, { "id": "R-BTA-9854311", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9854311", "resource": "Reactome", "description": "Maturation of TCA enzymes and regulation of TCA cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QMP7-1", "protein_name": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1", "gene_name": "sirt3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLYLNTFLPSVCRRCFAENLLWRRGLTTTQNLSRTKLVHQKTLSHFPHAQKGAAFLSQFIYCPAAFIKCGGTRGLFGGGRDNVHQQTLEDIAEKIRERKFKRIVVMAGAGISTPSGIPDFRSPGSGLYDNLQQYNLPYAEAIFEINYFHHNPNPFFALAKELYPGNYQPNLTHYFIRMLHDKEQLLRMYTQNIDGLERMAGIPPKMLVEAHGTFATATCTVCRRDYKGEELRDDIMAGTVPKCPTCKGIIKPDIVFFGEELPQHFFTYLTDFPIADLLIVMGTSLEVEPFASLAGAVRGSVPRLLINRDLVGPFASGSQRHTDVAELGDVVNGVKKLVELLGWKQELEDLMNVGRDKV", "length": 358 }, "evidence": [ { "id": "G5E521", "url": "https://omabrowser.org/oma/group/G5E521/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7JE69-1", "protein_name": "NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X2", "gene_name": "Sirt3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALSGRLALAALRLWGPGDVPQQPEATQDNAQISEWTISQTKAGPDSRLQGGLYPRSITGGRRPISLSVGASGSFGCGGNSEKVKLSLKDVAELLRTRACRRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFTLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPVSKLVEAHGSFASATCTVCRRSFPGEDFRADVMADRVPCCPVCTGVVKPDIVFFGEPLPARFLLHVADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGSFAYSPRSTDVVQLGDVVQSVERLVDLLGWTQELQDLIQRETGKLDGQDR", "length": 362 }, "evidence": [ { "id": "G5E521", "url": "https://omabrowser.org/oma/group/G5E521/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8R104-1", "protein_name": "NAD-dependent protein deacetylase sirtuin-3", "gene_name": "Sirt3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALDPLGAVVLQSIMALSGRLALAALRLWGPGGGRRPISLCVGASGGFGGGGSSEKKFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDGQDR", "length": 334 }, "evidence": [ { "id": "G5E521", "url": "https://omabrowser.org/oma/group/G5E521/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "NAD+ binding", "id": "GO:0070403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070403", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "histone deacetylase activity, NAD-dependent", "id": "GO:0017136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017136", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "NAD-dependent protein lysine delactylase activity", "id": "GO:0141208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141208", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of oxidative phosphorylation", "id": "GO:1903862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903862", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "aerobic respiration", "id": "GO:0009060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009060", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "positive regulation of ceramide biosynthetic process", "id": "GO:2000304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000304", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial transcription", "id": "GO:1903109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903109", "evidence": [ { "database": "UniProtKB", "id": "G5E521", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "43636", "name": "", "equation": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E521-1", "Q1JQC6-1", "Q0P595-1", "A0AAA9SJA1-1" ], "evidence": [ { "id": "43636", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43636" } ] }, { "id": "83535", "name": "", "equation": "N(6)-benzoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-benzoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QK60-1", "G5E521-1" ], "evidence": [ { "id": "83535", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83535" } ] }, { "id": "R-BTA-5688289", "name": "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-5688337" ], "enzyme_list": [ "Q04467-1", "G5E521-1", "A0A140T871-1", "E1BHL1-1" ], "evidence": [ { "id": "R-BTA-5688289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5688289" } ] }, { "id": "R-BTA-9620532", "name": "SIRT1,SIRT3 deacetylate FOXO3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-9620514" ], "output_participant_list": [], "enzyme_list": [ "G5E521-1", "F1MQB8-1" ], "evidence": [ { "id": "R-BTA-9620532", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9620532" } ] }, { "id": "R-BTA-9841847", "name": "SIRT3 deacetylates Ac-K272,K290-FOXO3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-BTA-9841849" ], "output_participant_list": [ "R-BTA-9841824" ], "enzyme_list": [ "G5E521-1" ], "evidence": [ { "id": "R-BTA-9841847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841847" } ] }, { "id": "R-BTA-9854463", "name": "SIRT3 deacetylates AcK-IDH2 dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q04467-1", "G5E521-1" ], "evidence": [ { "id": "R-BTA-9854463", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9854463" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5688337", "participant_name": "2'-O-acetyl-ADP-ribose [mitochondrial matrix]", "crossref": [ { "id": "83767", "database": "ChEBI", "url": "" }, { "id": "ZINC000096095472", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-BTA-9620514", "participant_name": "FOXO3 [nucleoplasm]", "crossref": [ { "id": "F1N4K5", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000011234", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000014920", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000014920", "database": "ENSEMBL", "url": "" }, { "id": "NP_001193012.1", "database": "RefSeq", "url": "" }, { "id": "XP_005210861.1", "database": "RefSeq", "url": "" }, { "id": "29099", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9841824", "participant_name": "FOXO3 [mitochondrial matrix]", "crossref": [ { "id": "ENSBTAG00000011234", "database": "ENSEMBL", "url": "" }, { "id": "XP_005210861.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAT00000014920", "database": "ENSEMBL", "url": "" }, { "id": "F1N4K5", "database": "UniProt", "url": "" }, { "id": "NP_001193012.1", "database": "RefSeq", "url": "" }, { "id": "29099", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000014920", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-9841849", "participant_name": "FOXO3 [mitochondrial matrix]", "crossref": [ { "id": "F1N4K5", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000011234", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000014920", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000014920", "database": "ENSEMBL", "url": "" }, { "id": "NP_001193012.1", "database": "RefSeq", "url": "" }, { "id": "XP_005210861.1", "database": "RefSeq", "url": "" }, { "id": "29099", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T871", "gene_name": "GLUD1", "activity": [ { "ec_number": "1.4.1.3", "activity": "L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+).", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] }, { "ec_number": "1.4.1.3", "activity": "", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] } ] }, { "uniprot_ac": "A0AAA9SJA1", "gene_name": "SIRT6", "activity": [ { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "A0AAA9SJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA1" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "A0AAA9SJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA1" } ] } ] }, { "uniprot_ac": "E1BHL1", "gene_name": "SOD2", "activity": [ { "ec_number": "1.15.1.1", "activity": "2 superoxide + 2 H(+) = H2O2 + O2.", "evidence": [ { "id": "E1BHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ] }, { "ec_number": "1.15.1.1", "activity": "", "evidence": [ { "id": "E1BHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHL1" } ] } ] }, { "uniprot_ac": "F1MQB8", "gene_name": "SIRT1", "activity": [ { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "F1MQB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQB8" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "F1MQB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQB8" } ] } ] }, { "uniprot_ac": "F6QK60", "gene_name": "SIRT2", "activity": [ { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "F6QK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QK60" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "F6QK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QK60" } ] } ] }, { "uniprot_ac": "G5E521", "gene_name": "SIRT3", "activity": [ { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" } ] } ] }, { "uniprot_ac": "Q04467", "gene_name": "IDH2", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "Q04467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04467" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "Q04467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04467" } ] } ] }, { "uniprot_ac": "Q0P595", "gene_name": "SIRT7", "activity": [ { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q0P595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P595" } ] }, { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "Q0P595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P595" } ] }, { "ec_number": "2.3.1.286", "activity": "", "evidence": [ { "id": "Q0P595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P595" } ] } ] }, { "uniprot_ac": "Q1JQC6", "gene_name": "SIRT4", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "Q1JQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQC6" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q1JQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQC6" } ] }, { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "Q1JQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQC6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E521-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 333, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E521-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E521" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" }, { "id": "PS50305", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50305" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Deacetylase sirtuin-type", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 313, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 189, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 189, "end_pos": 189, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 192, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 192, "end_pos": 192, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 213, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 213, "end_pos": 213, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E521" }, { "id": "PRU00236", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00236" }, { "id": "PIRSR037938-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR037938-3" } ], "binding_site_uniprot": 216, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 216, "end_pos": 216, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.286", "ec_name": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "2.3.1.286", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.286" }, { "id": "2.3.1.286", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.286" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E527-1", "uniprot_ac": "G5E527", "uniprot_id": "G5E527_BOVIN", "mass": { "chemical_mass": 82276.0, "monoisotopic_mass": 82276.0 }, "refseq": { "ac": "XP_024850905", "name": "proprotein convertase subtilisin/kexin type 4 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850905" }, "gene_names": [ { "name": "PCSK4", "type": "recommended", "evidence": [ { "id": "G5E527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ] }, { "name": "PCSK4", "type": "synonym", "evidence": [ { "id": "XP_024850905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850905" } ] } ], "protein_names": [ { "name": "Proprotein convertase subtilisin/kexin type 4", "type": "synonym", "evidence": [ { "id": "G5E527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E527/entry#names_and_taxonomy" } ] }, { "name": "proprotein convertase subtilisin/kexin type 4 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_024850905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850905" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCSK4", "url": "https://www.uniprot.org/uniprotkb/G5E527", "locus": { "chromosome": "7", "start_pos": 43888435, "end_pos": 43894811, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002305", "url": "https://www.ensembl.org/id/ENSBTAG00000002305" } ] } } ], "crossref": [ { "id": "G5E527", "url": "https://alphafold.ebi.ac.uk/entry/G5E527", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002305", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002305", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00064", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00064", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508744", "url": "https://www.ncbi.nlm.nih.gov/gene/508744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508744", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508744", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDGTCQE", "url": "https://omabrowser.org/oma/group/RDGTCQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E527", "url": "https://www.orthodb.org/?gene=G5E527", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42884:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024850905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850905", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E527-1", "url": "https://www.uniprot.org/uniprotkb/G5E527-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPARTALCLRLTLALGLALVGPMAVGWASARAPIYVSSWAVRVSQGYQEVDRLARKFGFVNFGQIFPDGQYFHLRHRGVVQQSLTPHWGHRLRLKKDPKVQWFQQQTVQRRVKRSLVVPTDPWFSKQWYMNNEMQSDLNILQVWSQGLSGQGVVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSDENRHGTRCAGEVAAMANNRFCGAGVAYNTRIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGHVPWYSEACASTLTTTYSSGVATDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDMQHLVVRASRPAQLQAEDWRTNGAGRRVSHHYGYGLLDAALLVGLARSWLPTQPQKKCVIHIVHTRTPAGEALAPIPILPVMHVRKNVSACAGHANSIRSLEHVQVQLSLSYSRRGDLEISLTSPMGTRSTLVAIRPFDVSSQGYNNWIFMSTHFWDEDPRGLWILGLENKGYYFNTGTLYRYTLLLYGTAEDMTARPSGPQVTSNACVQRDTEGLCQECHSPAYILGHLCLAYCPPRYFNHTQQAVTAGPGHSAVPAMRVCSSCHSSCYTCRGSSPLDCTACPPQSMLDEQQGSCSGLHPAEGHSHSTATACPYPHGPAQAVVLSLLAMAFGTPPPLPCSPHGLPAAMDGTP", "length": 752, "header": "tr|G5E527-1|G5E527_BOVIN Isoform 1 of Proprotein convertase subtilisin/kexin type 4 OS=Bos taurus OX=9913 GN=PCSK4 PE=3 SV=2 CANONICAL=G5E527-1" }, "isoforms": [ { "isoform_ac": "G5E527-1", "url": "https://www.uniprot.org/uniprotkb/G5E527/entry", "sequence": { "sequence": "MRPARTALCLRLTLALGLALVGPMAVGWASARAPIYVSSWAVRVSQGYQEVDRLARKFGFVNFGQIFPDGQYFHLRHRGVVQQSLTPHWGHRLRLKKDPKVQWFQQQTVQRRVKRSLVVPTDPWFSKQWYMNNEMQSDLNILQVWSQGLSGQGVVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSDENRHGTRCAGEVAAMANNRFCGAGVAYNTRIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGHVPWYSEACASTLTTTYSSGVATDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDMQHLVVRASRPAQLQAEDWRTNGAGRRVSHHYGYGLLDAALLVGLARSWLPTQPQKKCVIHIVHTRTPAGEALAPIPILPVMHVRKNVSACAGHANSIRSLEHVQVQLSLSYSRRGDLEISLTSPMGTRSTLVAIRPFDVSSQGYNNWIFMSTHFWDEDPRGLWILGLENKGYYFNTGTLYRYTLLLYGTAEDMTARPSGPQVTSNACVQRDTEGLCQECHSPAYILGHLCLAYCPPRYFNHTQQAVTAGPGHSAVPAMRVCSSCHSSCYTCRGSSPLDCTACPPQSMLDEQQGSCSGLHPAEGHSHSTATACPYPHGPAQAVVLSLLAMAFGTPPPLPCSPHGLPAAMDGTP", "length": 752, "header": "tr|G5E527-1|G5E527_BOVIN Isoform 1 of Proprotein convertase subtilisin/kexin type 4 OS=Bos taurus OX=9913 GN=PCSK4 PE=3 SV=2 CANONICAL=G5E527-1" }, "locus": { "chromosome": "7", "start_pos": 43894710, "end_pos": 43888884, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002975.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002975.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002975.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002975.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 647, "start_aa": "Thr", "end_pos": 647, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr647", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:508744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508744", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P29121-1", "protein_name": "Proprotein convertase subtilisin/kexin type 4", "gene_name": "Pcsk4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPSQTELWLGLTLTLALLAVRWASAQAPIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKDPKVRWFEQQTLRRRVKRSLVVPTDPWFSKQWYMNKEIQQDLNILKAWNQGLTGRGVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCAIRVVHTPTPILPRMLVPKNVTACSDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYFNTGTLYYYTLLLYGTAEDMTARPQAPQVTSRARACVQRDTEGLCQESHSPLSILAGLCLISSQQWWWLYSHPQQPVTEGQASCHPPVTPAAAA", "length": 655 }, "evidence": [ { "id": "G5E527", "url": "https://omabrowser.org/oma/group/G5E527/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UW60-1", "protein_name": "Proprotein convertase subtilisin/kexin type 4", "gene_name": "PCSK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPAPIALWLRLVLALALVRPRAVGWAPVRAPIYVSSWAVQVSQGNREVERLARKFGFVNLGPIFPDGQYFHLRHRGVVQQSLTPHWGHRLHLKKNPKVQWFQQQTLQRRVKRSVVVPTDPWFSKQWYMNSEAQPDLSILQAWSQGLSGQGIVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMANNGFCGVGVAFNARIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRVPWYSEACASTLTTTYSSGVATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEANPFLTWRDMQHLVVRASKPAHLQAEDWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQPQRKCAVRVQSRPTPILPLIYIRENVSACAGLHNSIRSLEHVQAQLTLSYSRRGDLEISLTSPMGTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYRYTLLLYGTAEDMTARPTGPQVTSSACVQRDTEGLCQACDGPAYILGQLCLAYCPPRFFNHTRLVTAGPGHTAAPALRVCSSCHASCYTCRGGSPRDCTSCPPSSTLDQQQGSCMGPTTPDSRPRLRAAACPHHRCPASAMVLSLLAVTLGGPVLCGMSMDLPLYAWLSRARATPTKPQVWLPAGT", "length": 755 }, "evidence": [ { "id": "G5E527", "url": "https://omabrowser.org/oma/group/G5E527/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q78EH2-1", "protein_name": "Proprotein convertase subtilisin/kexin type 4", "gene_name": "Pcsk4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPSQTALWLGLVLSLALLAVGWASARPPIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKEPKVRWFEQQTLRRRVKRSLVVPTDPWFSKQWYMNKEIEQDLNILKVWNQGLTGRGVVVSILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCTIRVVHTPTPILPRMLVPKNVTVCCDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYYNTGTLYYCTLLLYGTAEDMTARPQTPQESHCPLSIVAELCLISSKQWWWLYSHTQQPVTKGQDSCHPPTTPARQLDQRLHCLFPAPHAGSASEPLQGLSPLAAILAISLGPWCCPC", "length": 678 }, "evidence": [ { "id": "G5E527", "url": "https://omabrowser.org/oma/group/G5E527/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "pmid": "" }, { "name": "acrosomal membrane", "id": "GO:0002080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002080", "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "pmid": "" }, { "name": "peptide hormone processing", "id": "GO:0016486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016486", "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "G5E527", "url": "https://www.uniprot.org/uniprotkb/G5E527" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E527", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E527" }, { "id": "PS51829", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "P/Homo B", "eco_id": "ECO_0000259", "start_pos": 451, "end_pos": 592, "start_aa": "Thr", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 647 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 486, "end_pos": 488 }, { "start_pos": 640, "end_pos": 642 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E534-1", "uniprot_ac": "G5E534", "uniprot_id": "G5E534_BOVIN", "mass": { "chemical_mass": 32841.0, "monoisotopic_mass": 32841.0 }, "refseq": { "ac": "NP_001030510", "name": "ribose-5-phosphate isomerase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030510" }, "gene_names": [ { "name": "RPIA", "type": "recommended", "evidence": [ { "id": "G5E534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ] }, { "name": "RPIA", "type": "synonym", "evidence": [ { "id": "NP_001030510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030510" } ] } ], "protein_names": [ { "name": "Ribose-5-phosphate isomerase", "type": "recommended", "evidence": [ { "id": "G5E534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E534/entry#names_and_taxonomy" } ] }, { "name": "5.3.1.6", "type": "synonym", "evidence": [ { "id": "G5E534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E534/entry#names_and_taxonomy" } ] }, { "name": "Phosphoriboisomerase", "type": "synonym", "evidence": [ { "id": "G5E534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E534/entry#names_and_taxonomy" } ] }, { "name": "phosphoriboisomerase", "type": "synonym", "evidence": [ { "id": "NP_001030510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030510" } ] }, { "name": "ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)", "type": "synonym", "evidence": [ { "id": "NP_001030510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030510" } ] }, { "name": "ribose-5-phosphate isomerase", "type": "synonym", "evidence": [ { "id": "NP_001030510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030510" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPIA", "url": "https://www.uniprot.org/uniprotkb/G5E534", "locus": { "chromosome": "11", "start_pos": 47351604, "end_pos": 47386164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002866", "url": "https://www.ensembl.org/id/ENSBTAG00000002866" } ] } } ], "crossref": [ { "id": "G5E534", "url": "https://alphafold.ebi.ac.uk/entry/G5E534", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002866", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002866", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01398", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01398", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613376", "url": "https://www.ncbi.nlm.nih.gov/gene/613376", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613376", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613376", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACHVQEK", "url": "https://omabrowser.org/oma/group/ACHVQEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E534", "url": "https://www.orthodb.org/?gene=G5E534", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11934:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11934:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-71336", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71336", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73843", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73843", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001030510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14657", "url": "https://www.rhea-db.org/rhea/14657", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E534-1", "url": "https://www.uniprot.org/uniprotkb/G5E534-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWGVPGSHVQLPGRSQFGAGSTSTGVRETNIVCPGPSAMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVEQENLKLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGNASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRTVTQKFGGVIELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNIAIKMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPF", "length": 306, "header": "tr|G5E534-1|G5E534_BOVIN Isoform 1 of Ribose-5-phosphate isomerase OS=Bos taurus OX=9913 GN=RPIA PE=3 SV=1 CANONICAL=G5E534-1" }, "isoforms": [ { "isoform_ac": "G5E534-1", "url": "https://www.uniprot.org/uniprotkb/G5E534/entry", "sequence": { "sequence": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWGVPGSHVQLPGRSQFGAGSTSTGVRETNIVCPGPSAMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVEQENLKLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGNASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRTVTQKFGGVIELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNIAIKMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPF", "length": 306, "header": "tr|G5E534-1|G5E534_BOVIN Isoform 1 of Ribose-5-phosphate isomerase OS=Bos taurus OX=9913 GN=RPIA PE=3 SV=1 CANONICAL=G5E534-1" }, "locus": { "chromosome": "11", "start_pos": 47386160, "end_pos": 47351879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003719.5", "url": "https://www.ensembl.org/id/ENSBTAT00000003719.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003719.3", "url": "https://www.ensembl.org/id/ENSBTAP00000003719.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:613376", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613376", "resource": "KEGG Pathway" }, { "id": "R-BTA-71336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71336", "resource": "Reactome", "description": "Pentose phosphate pathway" }, { "id": "R-BTA-73843", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73843", "resource": "Reactome", "description": "5-Phosphoribose 1-diphosphate biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A7L6-1", "protein_name": "Ribose-5-phosphate isomerase", "gene_name": "Rpia", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNNWGLSGSHVQLPGRTQSETRGDKGGSSAGGPAPSTMSKAEEAKKLASHTAVENHVKNNQVLGIGSGSTIVHAVQRIAERVKQENLDLICIPTSFQARQLILQYGLTLSDLDQHPEIDLAIDGADEVDAELNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNLGDRWHKGIPIEVIPMAYVPVSRAVTQKFGGEVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWGEVNTAIKMTPGVVDTGLFINMAERVYFGMQDGSVNVREKPF", "length": 303 }, "evidence": [ { "id": "G5E534", "url": "https://omabrowser.org/oma/group/G5E534/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1STC1-1", "protein_name": "Ribose-5-phosphate isomerase", "gene_name": "RPIA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWGVLGSHVQPPGRAQFGVGSTSTSSGDANSVCPAPSTMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVKQENLNLICIPTSFQARQLILQHGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGNASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRTVTQKFGGVIELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAITMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPF", "length": 306 }, "evidence": [ { "id": "G5E534", "url": "https://omabrowser.org/oma/group/G5E534/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P47968-1", "protein_name": "Ribose-5-phosphate isomerase", "gene_name": "Rpia", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNNWGLSGSHVQLPGRAHSETRGDKGGSSAGGPAPSTMSKAEEAKKLASHTAVENHVKNNQVLGIGSGSTIVHAVQRIAERVKQENLDLICIPTSFQARQLILQYGLTLSDLDQHPEIDLAIDGADEVDAELNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNLGDRWHKGIPIEVIPMAYVPVSRAVAQKFGGEVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAIKMTPGVVDTGLFINMAERVYFGMQDGSVNVREKPF", "length": 303 }, "evidence": [ { "id": "G5E534", "url": "https://omabrowser.org/oma/group/G5E534/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49247-1", "protein_name": "Ribose-5-phosphate isomerase", "gene_name": "RPIA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPAPSTMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVKQENLNLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRAVSQKFGGVVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPFC", "length": 311 }, "evidence": [ { "id": "G5E534", "url": "https://omabrowser.org/oma/group/G5E534/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12189-1", "protein_name": "Ribose-5-phosphate isomerase", "gene_name": "RKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAAGVPKIDALESLGNPLEDAKRAAAYRAVDENLKFDDHKIIGIGSGSTVVYVAERIGQYLHDPKFYEVASKFICIPTGFQSRNLILDNKLQLGSIEQYPRIDIAFDGADEVDENLQLIKGGGACLFQEKLVSTSAKTFIVVADSRKKSPKHLGKNWRQGVPIEIVPSSYVRVKNDLLEQLHAEKVDIRQGGSAKAGPVVTDNNNFIIDADFGEISDPRKLHREIKLLVGVVETGLFIDNASKAYFGNSDGSVEVTEK", "length": 258 }, "evidence": [ { "id": "G5E534", "url": "https://omabrowser.org/oma/group/G5E534/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8MLS2-1", "protein_name": "ribose-5-phosphate isomerase", "gene_name": "Rpi", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDDIALDAAKKTAARTAVDQWVTEDTKILGIGSGSTVVYAVQRIAERVWKEGELTDLICVPSSYQARHLILDYNLNLGDLDRNPNIDVAIDGADEVDRHMVLIKGGGGCLLQEKVVASCAKHFIVVADYTKNSIRLGEQWCRGVPIEVAPMAYVPIKLHIEALFGGEASLRMAKVKAGPIVTDNGNFLLDWKFIANREYDWDEVNRAITLIPGVLETGLFVNMAHKCYYGMANGSVKVQNK", "length": 241 }, "evidence": [ { "id": "G5E534", "url": "https://omabrowser.org/oma/group/G5E534/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9S726-1", "protein_name": "Probable ribose-5-phosphate isomerase 3, chloroplastic", "gene_name": "RPI3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLSFVSSSHLTLRTPSIALRSTGSSPRTSVSFSVKAQSVALSQDDLKKLAAEKAVEAIKPGMVLGLGTGSTAAFAVDQIGKLLSSGELYDIVGIPTSKRTEEQARSLGIPLVGLDTHPRIDLAIDGADEVDPNLDLVKGRGGALLREKMVEAVADKFIVVADDTKLVTGLGGSGLAMPVEVVQFCWNFNLIRLQDLFKEFGCESKLRVDGDGKPYVTDNSNYIIDLYFKTPLKDGFAAAKEIGKFQGVVEHGLFLGMATSVIIAGKNGVEVMTK", "length": 276 }, "evidence": [ { "id": "G5E534", "url": "https://omabrowser.org/oma/group/G5E534/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribose-5-phosphate isomerase activity", "id": "GO:0004751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004751", "evidence": [ { "database": "UniProtKB", "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "D-ribose metabolic process", "id": "GO:0006014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006014", "evidence": [ { "database": "UniProtKB", "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ], "pmid": "" }, { "name": "pentose-phosphate shunt, non-oxidative branch", "id": "GO:0009052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009052", "evidence": [ { "database": "UniProtKB", "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E534", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14657", "name": "", "equation": "aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T186-1", "G5E534-1" ], "evidence": [ { "id": "14657", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14657" } ] }, { "id": "R-BTA-177784", "name": "RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E534-1" ], "evidence": [ { "id": "R-BTA-177784", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-177784" } ] }, { "id": "R-BTA-71306", "name": "RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E534-1" ], "evidence": [ { "id": "R-BTA-71306", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71306" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "G5E534", "gene_name": "RPIA", "activity": [ { "ec_number": "5.3.1.6", "activity": "aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate.", "evidence": [ { "id": "G5E534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ] }, { "ec_number": "5.3.1.6", "activity": "", "evidence": [ { "id": "G5E534", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E534" } ] } ] }, { "uniprot_ac": "Q3T186", "gene_name": "RPIA", "activity": [ { "ec_number": "5.3.1.6", "activity": "aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate.", "evidence": [ { "id": "Q3T186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T186" } ] }, { "ec_number": "5.3.1.6", "activity": "", "evidence": [ { "id": "Q3T186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T186" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E534-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E534-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E534" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.3.1.6", "ec_name": "aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate.", "evidence": [ { "id": "5.3.1.6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.1.6" }, { "id": "5.3.1.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.3.1.6" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E538-1", "uniprot_ac": "G5E538", "uniprot_id": "G5E538_BOVIN", "mass": { "chemical_mass": 70667.0, "monoisotopic_mass": 70667.0 }, "refseq": { "ac": "XP_024850615", "name": "adhesion G protein-coupled receptor E3 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850615" }, "gene_names": [ { "name": "ADGRE3", "type": "recommended", "evidence": [ { "id": "G5E538", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E538" } ] }, { "name": "ADGRE3", "type": 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"https://www.uniprot.org/uniprotkb/G5E538", "locus": { "chromosome": "7", "start_pos": 11182196, "end_pos": 11118533, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002937", "url": "https://www.ensembl.org/id/ENSBTAG00000002937" } ] } } ], "crossref": [ { "id": "G5E538", "url": "https://alphafold.ebi.ac.uk/entry/G5E538", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002937", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "526347", "url": "https://www.ncbi.nlm.nih.gov/gene/526347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376892", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376892" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E544", "url": "https://www.uniprot.org/uniprotkb/G5E544#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E544", "url": "https://www.uniprot.org/uniprotkb/G5E544" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR6B3", "url": "https://www.uniprot.org/uniprotkb/G5E544", "locus": { "chromosome": "3", "start_pos": 118940486, "end_pos": 118941424, "strand": "+", "evidence": 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"OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0PK11-1", "protein_name": "Clarin-2", "gene_name": "CLRN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY", "length": 232 }, "evidence": [ { "id": "G5E553", "url": "https://omabrowser.org/oma/group/G5E553/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B2RVW2-1", "protein_name": "Clarin-2", "gene_name": "Clrn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"uniprot_canonical_ac": "D3ZL71-1", "protein_name": "Clarin 2", "gene_name": "Clrn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGWFKKVWYGLASLLSFSSFLLIIVALALPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHITILLLLFLALALALVSMGFAILNIIQVPYRAVNGPGGICLWNVLAGGVVALAISSFMAAVKFHDLTERIANFQERLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEVKTKMEEATVTPEDILY", "length": 232 }, "evidence": [ { "id": "G5E553", "url": "https://omabrowser.org/oma/group/G5E553/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HR09-1", "protein_name": "Clarin-2", "gene_name": "Clrn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPGWFKKVWYGLASLLSFSSFLLIIIALSVPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNASLHVTILLLLFLALALALVSMGFAILNIIQVPYRAVNGPGGICLWNILAGGVVALAIGSFMAAVKFHDLTERIANFQERLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKMEEATVTPEDILY", "length": 232 }, "evidence": [ { "id": "G5E553", "url": "https://omabrowser.org/oma/group/G5E553/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LUJ9-1", "protein_name": "Clarin 2", "gene_name": "CLRN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGWFKKVWYGLASLLSFSSFILIVIALVVPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRRSQFTIFPHLVRELNAGLHVMILLLLFLALALALVSTGFAILNMIQAPYRAVNGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFRFVVVEEQYEESFWICVASASAHATNLVVVAISQIPLPEMKTKIEEVTVTAEDILY", "length": 232 }, "evidence": [ { "id": "G5E553", "url": "https://omabrowser.org/oma/group/G5E553/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E553", "url": 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"uniprot_ac": "G5E561", "uniprot_id": "G5E561_BOVIN", "mass": { "chemical_mass": 68065.0, "monoisotopic_mass": 68065.0 }, "refseq": { "ac": "NP_001193713", "name": "proton channel OTOP1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193713" }, "gene_names": [ { "name": "OTOP1", "type": "recommended", "evidence": [ { "id": "G5E561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ] }, { "name": "OTOP1", "type": "synonym", "evidence": [ { "id": "NP_001193713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193713" } ] } ], "protein_names": [ { "name": "Otopetrin 1", "type": "synonym", "evidence": [ { "id": "G5E561", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E561/entry#names_and_taxonomy" } ] }, { "name": "proton channel OTOP1", "type": "synonym", "evidence": [ { "id": "NP_001193713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193713" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OTOP1", "url": "https://www.uniprot.org/uniprotkb/G5E561", "locus": { "chromosome": "6", "start_pos": 104932213, "end_pos": 104881314, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003651", "url": "https://www.ensembl.org/id/ENSBTAG00000003651" } ] } } ], "crossref": [ { "id": "G5E561", "url": "https://alphafold.ebi.ac.uk/entry/G5E561", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003651", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003651", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "525643", "url": "https://www.ncbi.nlm.nih.gov/gene/525643", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:525643", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525643", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HATTCWI", "url": "https://omabrowser.org/oma/group/HATTCWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E561", "url": "https://www.orthodb.org/?gene=G5E561", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193713", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E561-1", "url": "https://www.uniprot.org/uniprotkb/G5E561-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEGQGAPAAPLKAPSDSERGSSWPAARPPPLFLAPGFRGSPGSPAPRRGAVRESFPQKLAEALSSQYALNVFVAGLLFLLAWAVHASGVGKRDLLCFLTALMLLQLLWMLWYVRRSSAHRRLIRLKDTYAGARWLRGSITLFAVITIILGCLKIGYFIGFSGCLSATEGVFPVTHAVHTLLQVYFLWGHSKDIIQSFKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPPCNCTPPTLCLAISHGMYYLYPFNIEYQILASTMLYVLWKNIGRKVDSHQHQKMQFRSHGVLLGSVLGLTVLATTIGVVVVYLIQIGRSKTKSEAALIMFYLYASILLMLMGAAGLVGIRIYRLDEQSLDESKNPARKLDADLLVGTASGSWFISWGSILAILCAESRPPYTWYNLPYSILAVVEKYIQNLFIIESIHREPGKLSDDIRTLRVVTVYNGNAMSLPSSCLKNGPMAGDMAPQALEMPPAANGNTCLREVGGREKEDKSWERAQGSACHSCFLQDNAQRRVLRNIAAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI", "length": 612, "header": "tr|G5E561-1|G5E561_BOVIN Isoform 1 of Otopetrin 1 OS=Bos taurus OX=9913 GN=OTOP1 PE=3 SV=2 CANONICAL=G5E561-1" }, "isoforms": [ { "isoform_ac": "G5E561-1", "url": "https://www.uniprot.org/uniprotkb/G5E561/entry", "sequence": { "sequence": "MPEGQGAPAAPLKAPSDSERGSSWPAARPPPLFLAPGFRGSPGSPAPRRGAVRESFPQKLAEALSSQYALNVFVAGLLFLLAWAVHASGVGKRDLLCFLTALMLLQLLWMLWYVRRSSAHRRLIRLKDTYAGARWLRGSITLFAVITIILGCLKIGYFIGFSGCLSATEGVFPVTHAVHTLLQVYFLWGHSKDIIQSFKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPPCNCTPPTLCLAISHGMYYLYPFNIEYQILASTMLYVLWKNIGRKVDSHQHQKMQFRSHGVLLGSVLGLTVLATTIGVVVVYLIQIGRSKTKSEAALIMFYLYASILLMLMGAAGLVGIRIYRLDEQSLDESKNPARKLDADLLVGTASGSWFISWGSILAILCAESRPPYTWYNLPYSILAVVEKYIQNLFIIESIHREPGKLSDDIRTLRVVTVYNGNAMSLPSSCLKNGPMAGDMAPQALEMPPAANGNTCLREVGGREKEDKSWERAQGSACHSCFLQDNAQRRVLRNIAAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI", "length": 612, "header": "tr|G5E561-1|G5E561_BOVIN Isoform 1 of Otopetrin 1 OS=Bos taurus OX=9913 GN=OTOP1 PE=3 SV=2 CANONICAL=G5E561-1" }, "locus": { "chromosome": "6", "start_pos": 104931209, "end_pos": 104881314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004759.4", "url": "https://www.ensembl.org/id/ENSBTAT00000004759.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004759.3", "url": "https://www.ensembl.org/id/ENSBTAP00000004759.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:525643", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525643", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IM55-1", "protein_name": "Proton channel OTOP1", "gene_name": "Otop1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPGGPGAPSSPAAPPGSFSAAPSGSSACPPPPHPLARGSPPASGPRRGTSVPQKLAETLSSQYGLNVFVAGLLFLLAWAVHAAGVGKSDLLCVLTALMLLQLLWMLWYVGRSYVQRRLIRPKDTHAGARWLRGSITLFAFITVILGCLKVAYFIGFSECLSATEGVFPVTHAVHTLLQVYFLWGHAKDIILSFKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPQCNCTPPALCSALSHGIYYLYPFNIEYQILASTMLYVLWKNIGRRVDNSRHQKMQCRFDGVLVGAVLGLTVLAATIAVVVVYMIHIGRSKSKSESALILFYLYAITVLMLMGAAGLIGSWIYRVDEKSLDESKNPARKLDADLLVATASGSWLLSWGSILAIACAETRPPYTWYNLPYSVLVIVEKYVQNLFIIESVHREPEGVPEDVRTLRVVTVCSGEAATLAASSLGSQGLARDASAAVNGNLCLQQGRGKEDQEAGWEGAAGTARCPDFLQGGVKRRLLRNITAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAAALFEVYCKI", "length": 600 }, "evidence": [ { "id": "G5E561", "url": "https://omabrowser.org/oma/group/G5E561/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XZI6-1", "protein_name": "Otopetrin 1", "gene_name": "OTOP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKAGGWSSAGGSYPQKNAEILSSQYGINLFLAGLLLTFAWAVHAVGISKSHLLSYLITLMLVQLLWMLWYLCRSCTQRRLIRDKDTHAGARWLKCGITLFAVITLILDSFKIGYYIDFSNCLSPTEGIFPVTHAAHTILQVYFLWCHAKDIIQSFKTLERFGVIHSVFTNLLLWTNGVLTESKHQLNEHKERLITLGFGNITIVLDDHAPQCNCTTTTLCSIFSQGIYYLYPFNIEYHILASTMLYVLWKNIGRKVEHHQQHKTPFKFHGITVGMIFGLTVLTSTIAIVVVYLIQIGRSKIKSELALTMFYLHAIFVLALMCTAGVIALLIYRLEDRSLDNSKNPARKLDAELLVGTAAGSWLLSWGSILAIICAQAHPKYTWYNLPYSILVIIEKYIQNLFIIESIHREQEKVNDDVKTLRIVTVSRGSTLTLTPSYKEIYNGHAAQDTGELPCLFHGSICARERDESSGDSELTRQGNGSDMHFASEFSLCSRSSVADNKRRILKNIAAFLFLCNLSLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHSAASLFEVNCKT", "length": 576 }, "evidence": [ { "id": "G5E561", "url": "https://omabrowser.org/oma/group/G5E561/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7M734-1", "protein_name": "Proton channel OTOP1", "gene_name": "Otop1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGDRGALSSPAASSGSPSAAPSGIAACPPPPSPLARASPQASGPRRGASVPQKLAETLSSQYGLNVFVAGLLFLLAWAVHATGVGKSDLLCVLTALMLLQLLWMLWYVGRSYMQRRLIRPKDTHAGARWLRGSITLFAFITIVLGCLKVAYFIGFSECLSATEGVFPVTHAVHTLLQVYFLWGHAKDIIMSFKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPQCNCTPPALCSALSHGIYYLYPFNIEYQILASTMLYVLWKNIGRRVDSSRHQKMQCRFDGVLVGSVLGLTVLAATIAVVVVYMIHIGRSKSKSESALIMFYLYAITVLLLMGAAGLVGSWIYRVDEKSLDESKNPARKLDADLLVATASGSWLLSWGSILAIACAETRPPYTWYNLPYSVLVIVEKYVQNIFIIESVHLEPEGVPEDVRTLRVVTVCSGEAAALAASSLGSQGTAQDGSPAVNGNLHLQQRCEKEDQEADWEGATGTTRCLDFLQGGMKRRLLRNITAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAAALFEVYCKI", "length": 600 }, "evidence": [ { "id": "G5E561", "url": "https://omabrowser.org/oma/group/G5E561/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7RTM1-1", "protein_name": "Proton channel OTOP1", "gene_name": "OTOP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLEGLGSPASPRAAASASVAGSSGPAACSPPSSSAPRSPESPAPRRGGVRASVPQKLAEMLSSQYGLIVFVAGLLLLLAWAVHAAGVSKSDLLCFLTALMLLQLLWMLWYVGRSSAHRRLFRLKDTHAGAGWLRGSITLFAVITVILGCLKIGYFIGFSECLSATEGVFPVTHSVHTLLQVYFLWGHAKDIIQSFKTLERFGVIHSVFTNLLLWANGVLNESKHQLNEHKERLITLGFGNITTVLDDHTPQCNCTPPTLCTAISHGIYYLYPFNIEYQILASTMLYVLWKNIGRKVDSHQHQKMQFKSDGVMVGAVLGLTVLAATIAVVVVYLIHIGRSKTKSESALIMFYLYAITLLMLMGAAGLAGIRIYRIDEKSLDESKNPARKLDSDLLVGTASGSWLISWGSILAILCAEGHPRYTWYNLPYSILAIVEKYIQNLFIFESIHREPEKLSEDIQTLRVVTVCNGNTMPLASSCPKSGGVARDVAPQGKDMPPAANGNVCMRESHDKEEEKQEESSWGGSPSPVRLPRFLQGNAKRKVLRNIAAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI", "length": 612 }, "evidence": [ { "id": "G5E561", "url": "https://omabrowser.org/oma/group/G5E561/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80VM9-1", "protein_name": "Proton channel OTOP1", "gene_name": "Otop1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGGPGAPSSPAASSGSSRAAPSGIAACPLSPPPLARGSPQASGPRRGASVPQKLAETLSSQYGLNVFVAGLLFLLAWAVHATGVGKSDLLCVLTALMLLQLLWMLWYVGRSYMQRRLIRPKDTHAGARWLRGSITLFAFITVVLGCLKVAYFIGFSECLSATEGVFPVTHAVHTLLQVYFLWGHAKDIIMSFKTLERFGVIHSVFTNLLLWANSVLNESKHQLNEHKERLITLGFGNITIVLDDHTPQCNCTPPALCSALSHGIYYLYPFNIEYQILASTMLYVLWKNIGRRVDSSQHQKMQCRFDGVLVGSVLGLTVLAATIAVVVVYMIHIGRSKSKSESALIMFYLYAITVLLLMGAAGLVGSWIYRVDEKSLDESKNPARKLDVDLLVATGSGSWLLSWGSILAIACAETRPPYTWYNLPYSVLVIVEKYVQNIFIIESVHLEPEGVPEDVRTLRVVTVCSSEAAALAASTLGSQGMAQDGSPAVNGNLCLQQRCGKEDQESGWEGATGTTRCLDFLQGGMKRRLLRNITAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAAALFEVYCKI", "length": 600 }, "evidence": [ { "id": "G5E561", "url": "https://omabrowser.org/oma/group/G5E561/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" }, { "name": "negative regulation of type II interferon-mediated signaling pathway", "id": "GO:0060336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060336", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" }, { "name": "otolith formation", "id": "GO:0032475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032475", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" }, { "name": "otolith mineralization", "id": "GO:0045299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045299", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" }, { "name": "proton channel activity", "id": "GO:0015252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015252", "evidence": [ { "database": "UniProtKB", "id": "G5E561", "url": "https://www.uniprot.org/uniprotkb/G5E561" } ], "pmid": "" } ] } ] }, 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 554, "end_pos": 556 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX13-1", "uniprot_ac": "G3MX13", "uniprot_id": "G3MX13_BOVIN", "mass": { "chemical_mass": 83795.0, "monoisotopic_mass": 83795.0 }, "refseq": { "ac": "XP_005219111", "name": "low-density lipoprotein receptor-related protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219111" }, "gene_names": [ { "name": "LRP3", "type": "recommended", "evidence": [ { "id": "G3MX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX13" } ] }, { "name": "LRP3", "type": "synonym", "evidence": [ { "id": "XP_005219111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219111" } ] } ], "protein_names": [ { "name": "Low-density lipoprotein receptor-related protein 3", "type": "recommended", "evidence": [ { "id": "G3MX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX13/entry#names_and_taxonomy" } ] }, { "name": "105 kDa low-density lipoprotein receptor-related protein", "type": "synonym", "evidence": [ { "id": "G3MX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX13/entry#names_and_taxonomy" } ] }, { "name": "low-density lipoprotein receptor-related protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005219111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219111" } ] } ], "function": [ { "annotation": "Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. 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"MEKRAAAGPEGAPGARAQLAVVCLVNIVLTGRFSSAVPALGEASASQPPLLTAACSGQLERHTARRGVIYSPAWPLNYPPGTNCSWYIQGDRGDMITISFRNFDVEESHQCSLDWLMLGPAAPPRQEAFRLCGSAIPPAFISARDHVWIFFHSDTSSSGQAQGFRLSYIRGKLGQASCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARSTRCLPAERRCDGTQDCGDGSDEAGCPDLACGRRLGSFYGSFASPDLFGAARGPSDLHCTWLVDTQDPRRVLLQLELRLGYDDYVQVYEGLGERGDRLLQTLSYRSNHRPVSLEAAQGRLTVAYHARARSAGHGFNATYQVKGYCLPWEQPCGSSREGDAEDPGEQGCFSEPQRCDGWWHCASGRDEQGCPACPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKNCFSCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGCLAAVPRKVITAALIGSLVCGLLLVIALGCAFKLYSLRTQEYRAFETQMTRLEAEFVRREAPPSYGQLIAQGLIPPVEDFPVYSASQASVLQNLRTAMRRQMRRHASRRGPSRRRLGRLWNRLFHRPRAPRGQIPLLTAARTSQTVLGDGLLQPAPGAARDPPAPLTDTSSPGAAGEGSPGAPSHASEVGPPVPPPSGLRDPLESRPADKDRKAGRDPLVDSPAPVDVPQESCSGQDPHPPALTAGSTLGPHPSEPLGVCRSPPPPCSPTLEASDDEALLVC", "length": 782, "header": "tr|G3MX13-1|G3MX13_BOVIN Isoform 1 of Low-density lipoprotein receptor-related protein 3 OS=Bos taurus OX=9913 GN=LRP3 PE=3 SV=4 CANONICAL=G3MX13-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW6/entry", "sequence": { "sequence": "MVKALVPKPEKIQASPLPLNIVLTGRFSSAVPALGEASASQPPLLTAACSGQLERHTARRGVIYSPAWPLNYPPGTNCSWYIQGDRGDMITISFRNFDVEESHQCSLDWLMLGPAAPPRQEAFRLCGSAIPPAFISARDHVWIFFHSDTSSSGQAQGFRLSYIRGKLGQASCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARSTRCLPAERRCDGTQDCGDGSDEAGCPDLACGRRLGSFYGSFASPDLFGAARGPSDLHCTWLVDTQDPRRVLLQLELRLGYDDYVQVYEGLGERGDRLLQTLSYRSNHRPVSLEAAQGRLTVAYHARARSAGHGFNATYQVKGYCLPWEQPCGSSREGDAEDPGEQGCFSEPQRCDGWWHCASGRDEQGCPACPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKNCFSCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGCLAAVPRKVITAALIGSLVCGLLLVIALGCAFKLYSLRTQEYRAFETQMTRLEAEFVRREAPPSYGQLIAQGLIPPVEDFPVYSASQASVLQNLRTAMRRQMRRHASRRGPSRRRLGRLWNRLFHRPRAPRGQIPLLTAARTSQTVLGDGLLQPAPGAARDPPAPLTDTSSPGAAGEGSPGAPSHASEVGPPVPPPSGLRDPLESRPADKDRKAGRDPLVDSPAPVDVPQESCSGQDPHPPALTAGSTLGPHPSEPLGVCRSPPPPCSPTLEASDDEALLVC", "length": 776, "header": "tr|A0A3Q1LQW6-1|A0A3Q1LQW6_BOVIN Computationally mapped isoform of Low-density lipoprotein receptor-related protein 3 OS=Bos taurus OX=9913 GN=LRP3 PE=3 SV=2 CANONICAL=G3MX13-1" }, "locus": { "chromosome": "18", "start_pos": 43643569, "end_pos": 43633201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066838.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066838.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057413.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057413.2" } ] } }, { "isoform_ac": "G3MX13-1", "url": "https://www.uniprot.org/uniprotkb/G3MX13/entry", "sequence": { "sequence": "MEKRAAAGPEGAPGARAQLAVVCLVNIVLTGRFSSAVPALGEASASQPPLLTAACSGQLERHTARRGVIYSPAWPLNYPPGTNCSWYIQGDRGDMITISFRNFDVEESHQCSLDWLMLGPAAPPRQEAFRLCGSAIPPAFISARDHVWIFFHSDTSSSGQAQGFRLSYIRGKLGQASCQADEFRCDNGKCLPGPWQCNTVDECGDGSDEGNCSAPASEPPGSLCPGGTFPCSGARSTRCLPAERRCDGTQDCGDGSDEAGCPDLACGRRLGSFYGSFASPDLFGAARGPSDLHCTWLVDTQDPRRVLLQLELRLGYDDYVQVYEGLGERGDRLLQTLSYRSNHRPVSLEAAQGRLTVAYHARARSAGHGFNATYQVKGYCLPWEQPCGSSREGDAEDPGEQGCFSEPQRCDGWWHCASGRDEQGCPACPPDQYPCEGGSGLCYTPADRCNNQKSCPDGADEKNCFSCQPGTFHCGTNLCIFETWRCDGQEDCQDGSDEHGCLAAVPRKVITAALIGSLVCGLLLVIALGCAFKLYSLRTQEYRAFETQMTRLEAEFVRREAPPSYGQLIAQGLIPPVEDFPVYSASQASVLQNLRTAMRRQMRRHASRRGPSRRRLGRLWNRLFHRPRAPRGQIPLLTAARTSQTVLGDGLLQPAPGAARDPPAPLTDTSSPGAAGEGSPGAPSHASEVGPPVPPPSGLRDPLESRPADKDRKAGRDPLVDSPAPVDVPQESCSGQDPHPPALTAGSTLGPHPSEPLGVCRSPPPPCSPTLEASDDEALLVC", "length": 782, "header": "tr|G3MX13-1|G3MX13_BOVIN Isoform 1 of Low-density lipoprotein receptor-related protein 3 OS=Bos taurus OX=9913 GN=LRP3 PE=3 SV=4 CANONICAL=G3MX13-1" }, "locus": { "chromosome": "18", "start_pos": 43643569, "end_pos": 43631626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065603.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065603.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054071.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054071.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100301323", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301323", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "G3MX13", "url": "https://www.uniprot.org/uniprotkb/G3MX13" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": 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regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "G3MX13", "url": "https://www.uniprot.org/uniprotkb/G3MX13" } ], "pmid": "" }, { "name": "negative regulation of fat cell differentiation", "id": "GO:0045599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045599", "evidence": [ { "database": "UniProtKB", "id": "G3MX13", "url": "https://www.uniprot.org/uniprotkb/G3MX13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": 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"F6RY99", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RY99", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6RY99", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RY99", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "F6RY99", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ], "pmid": "" }, { "name": "alpha-beta T cell receptor complex", "id": "GO:0042105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042105", "evidence": [ { "database": "UniProtKB", "id": "F6RY99", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1ME76-1", "F1MRH9-1", "A0AAF6DLF7-1", "A0AAA9S9Q3-1", "E1BFE2-1", "E1BL76-1", "G3MXS7-1", "A0A3Q1LUB1-1", "A0AAA9THG9-1", "F1N339-1", "F6RY99-1", "A0AAF6YUC8-1", "A0AAA9RTM1-1", "A0AAA9SMJ6-1", "A0A3Q1LZA9-1", "A7MBD1-1", "A5D7P0-1", "Q58DB6-1", "A0AAA9SEK4-1", "E1BDH9-1", "F1MGK4-1", "E1BIH4-1", "A0A3Q1M6K1-1", "E1BIU8-1", "A7MBJ4-1", "A6H730-1", "A0A3Q1MFX2-1", "A0AAA9U0H6-1", "A2VDT1-1", "E1BPU9-1", "P0C591-1", "P11064-1", "Q0IID7-1", "Q2KJ36-1", "Q2T9S4-1", "E1BPA0-1", "A0AAA9TAZ9-1", "Q5BIP9-1", "A0A3Q1M5K4-1", "F1MM08-1", "E1BJR7-1", "Q17QJ3-1", "Q17QM8-1", "F1MD22-1", "F1MI99-1", "F1MP34-1", "F1MGK5-1", "F1MEZ2-1", "F1MQM7-1", "E1BEZ8-1", "A0A3Q1M0B4-1", "A0AAA9S7W5-1", "A0A3Q1N8V6-1", "A0AAA9TFV5-1", "A0A3Q1MBB1-1", "F1MTZ3-1", "A0AAF6Z8C2-1", "F1MDF1-1", "A0AAA9T5N9-1", "E1BKT4-1", "A0A3Q1MH98-1", "F1N6L3-1", "F1MW70-1", "F1MXF2-1", "A0AAA9TWD1-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-BTA-205306", "name": "Interaction of SHP1 and KIT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RY99-1", "P43481-1" ], "evidence": [ { "id": "R-BTA-205306", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-205306" } ] }, { "id": "R-BTA-210277", "name": "Interaction of PECAM-1 and SHP-1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RY99-1" ], "evidence": [ { "id": "R-BTA-210277", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210277" } ] }, { "id": "R-BTA-389758", "name": "Dephosphorylation of CD3-zeta by PD-1 bound phosphatases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VBZ0-1", "F1N339-1", "F6RY99-1" ], "evidence": [ { "id": "R-BTA-389758", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389758" } ] }, { "id": "R-BTA-389759", "name": "Interaction of SHP-1 or SHP-2 with phospho PD-1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VBZ0-1", "F1N339-1", "F6RY99-1" ], "evidence": [ { "id": "R-BTA-389759", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389759" } ] }, { "id": "R-BTA-453200", "name": "SYK autophosphorylates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N339-1", "F6RY99-1", "A0A3Q1MHG9-1", "A0JNB0-1", "F1N261-1" ], "evidence": [ { "id": "R-BTA-453200", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-453200" } ] }, { "id": "R-BTA-5684169", "name": "G6B binds PTPN6,PTPN11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N339-1", "F6RY99-1" ], "evidence": [ { "id": "R-BTA-5684169", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5684169" } ] }, { "id": "R-BTA-5684801", "name": "p-Y7-CLEC1B dimer:PDPN binds SYK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N339-1", "F6RY99-1", "A0A3Q1MHG9-1" ], "evidence": [ { "id": "R-BTA-5684801", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5684801" } ] }, { "id": "R-BTA-5690701", "name": "SHP1 binds p-CD22", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RY99-1" ], "evidence": [ { "id": "R-BTA-5690701", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690701" } ] }, { "id": "R-BTA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P24627-1", "Q3SZH7-1", "A0AAA9S4U4-1", "A0AAA9S9V5-1", "O46414-1", "P25326-1", "F1MMR6-1", "P80189-1", "P52176-1", "Q17QB3-1", "A7YWG4-1", "F1MJ59-1", "F6RY99-1", "A0A140T8A5-1" ], "evidence": [ { "id": "R-BTA-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798745" } ] }, { "id": "R-BTA-6798749", "name": "Exocytosis of specific granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, specific granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P24627-1", "A0AAA9S9V5-1", "F1N1G1-1", "Q0II59-1", "F1MMR6-1", "P05689-1", "P80189-1", "A7YWG4-1", "E1BPI3-1", "F1MJ59-1", "F6RY99-1", "A6BMK7-1", "Q2KJ64-1" ], "evidence": [ { "id": "R-BTA-6798749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798749" } ] }, { "id": "R-BTA-873918", "name": "Transphosphorylation of JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F6RY99-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873918", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873918" } ] }, { "id": "R-BTA-909738", "name": "SHP1 and SHP2 bind the common beta chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1N339-1", "F6RY99-1" ], "evidence": [ { "id": "R-BTA-909738", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909738" } ] }, { "id": "R-BTA-913424", "name": "The SHC1:SHIP1 complex is stabilized by GRB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "F6RY99-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-913424", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913424" } ] }, { "id": "R-BTA-914036", "name": "SHP1 and SHP2 dephosphorylate Y628 of IL3RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1N339-1", "F6RY99-1" ], "evidence": [ { "id": "R-BTA-914036", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-914036" } ] }, { "id": "R-BTA-9701507", "name": "PTPN6 dephosphorylates JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MKW9-1", "E1BEL4-1", "F6RY99-1" ], "evidence": [ { "id": "R-BTA-9701507", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9701507" } ] }, { "id": "R-BTA-983707", "name": "SYK autophosphorylates at the activated BCR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RY99-1", "A0A3Q1MHG9-1" ], "evidence": [ { "id": "R-BTA-983707", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983707" } ] }, { "id": "R-BTA-997314", "name": "Dephosphorylation of JAK1 by SHP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "F6RY99-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-997314", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-997314" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8A5", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] } ] }, { "uniprot_ac": "A0A3Q1LUB1", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] } ] }, { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B4", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] } ] }, { "uniprot_ac": "A0A3Q1M5K4", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1MBB1", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] } ] }, { "uniprot_ac": "A0A3Q1MFX2", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MHG9", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] } ] }, { "uniprot_ac": "A0A3Q1MKW9", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKW9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MKW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKW9" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S4U4", "gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] } ] }, { "uniprot_ac": "A0AAA9S7W5", "gene_name": "PTPRV", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] } ] }, { "uniprot_ac": "A0AAA9S9Q3", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] } ] }, { "uniprot_ac": "A0AAA9S9V5", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] } ] }, { "uniprot_ac": "A0AAA9SEK4", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] } ] }, { "uniprot_ac": "A0AAA9SMJ6", "gene_name": "PTPRH", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAA9TAZ9", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] } ] }, { "uniprot_ac": "A0AAA9TFV5", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] } ] }, { "uniprot_ac": "A0AAA9THG9", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] } ] }, { "uniprot_ac": "A0AAA9TWD1", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YUC8", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A2VDT1", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] } ] }, { "uniprot_ac": "A5D7P0", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] } ] }, { "uniprot_ac": "A6BMK7", "gene_name": "NEU1", "activity": [ { "ec_number": "3.2.1.18", "activity": "Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.", "evidence": [ { "id": "A6BMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6BMK7" } ] }, { "ec_number": "3.2.1.18", "activity": "", "evidence": [ { "id": "A6BMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6BMK7" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7MBJ4", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] } ] }, { "uniprot_ac": "A7YWG4", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A7YWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YWG4" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A7YWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YWG4" } ] } ] }, { "uniprot_ac": "E1BDH9", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BEZ8", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "E1BIH4", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] } ] }, { "uniprot_ac": "E1BIU8", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] } ] }, { "uniprot_ac": "E1BJR7", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] } ] }, { "uniprot_ac": "E1BKT4", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ] }, { "uniprot_ac": "E1BL76", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPU9", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MD22", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] } ] }, { "uniprot_ac": "F1MDF1", "gene_name": "PTPN18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MGK4", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] } ] }, { "uniprot_ac": "F1MGK5", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MJ59", "gene_name": "NIT2", "activity": [ { "ec_number": "3.5.1.3", "activity": "2-oxosuccinamate + H2O = oxaloacetate + NH4(+).", "evidence": [ { "id": "F1MJ59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ59" } ] }, { "ec_number": "3.5.1.3", "activity": "", "evidence": [ { "id": "F1MJ59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ59" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MMR6", "gene_name": "CTSD", "activity": [ { "ec_number": "3.4.23.5", "activity": "Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MRH9", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] } ] }, { "uniprot_ac": "F1MTZ3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1MXF2", "gene_name": "MDP1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXF2" } ] } ] }, { "uniprot_ac": "F1N1G1", "gene_name": "HPSE", "activity": [ { "ec_number": "3.2.1.166", "activity": "endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan.", "evidence": [ { "id": "F1N1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1G1" } ] }, { "ec_number": "3.2.1.166", "activity": "", "evidence": [ { "id": "F1N1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1G1" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N339", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] } ] }, { "uniprot_ac": "F1N6L3", "gene_name": "PTPN22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L3" } ] } ] }, { "uniprot_ac": "F6RY99", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] } ] }, { "uniprot_ac": "G3MXS7", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3MXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXS7" } ] } ] }, { "uniprot_ac": "O46414", "gene_name": "FTH1", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] } ] }, { "uniprot_ac": "P05689", "gene_name": "CTSZ", "activity": [ { "ec_number": "3.4.18.1", "activity": "Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] }, { "ec_number": "3.4.18.1", "activity": "", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P11064", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] } ] }, { "uniprot_ac": "P24627", "gene_name": "LTF", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "P24627", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P24627" } ] } ] }, { "uniprot_ac": "P25326", "gene_name": "CTSS", "activity": [ { "ec_number": "3.4.22.27", "activity": "Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] }, { "ec_number": "3.4.22.27", "activity": "", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": "P52176", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] } ] }, { "uniprot_ac": "P80189", "gene_name": "LYS", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P80189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80189" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P80189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80189" } ] } ] }, { "uniprot_ac": "Q0II59", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "Q0II59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II59" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "Q0II59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II59" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q17QB3", "gene_name": "ASAH1", "activity": [ { "ec_number": "3.5.1.23", "activity": "an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid.", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] }, { "ec_number": "3.5.1.23", "activity": "", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] }, { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] } ] }, { "uniprot_ac": "Q17QJ3", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] } ] }, { "uniprot_ac": "Q17QM8", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", 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"categories": [ "Protein Classification" ] }, { "id": "F1MIV9", "url": "https://www.orthodb.org/?gene=F1MIV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MY23", "url": "https://www.orthodb.org/?gene=G3MY23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYG1", "url": "https://www.orthodb.org/?gene=G3MYG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N0P4", "url": "https://www.orthodb.org/?gene=G3N0P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N0R1", "url": "https://www.orthodb.org/?gene=G3N0R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N2Z7", "url": "https://www.orthodb.org/?gene=G3N2Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11685", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11685", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5675482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5689877", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689877", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9646399", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9646399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024852460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852460", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TGG9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGG9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQT1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQT1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U024", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U024", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U024-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U024-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIV9", "url": "https://www.uniprot.org/uniprotkb/F1MIV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIV9-1", "url": "https://www.uniprot.org/uniprotkb/F1MIV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY23", "url": "https://www.uniprot.org/uniprotkb/G3MY23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY23-1", "url": "https://www.uniprot.org/uniprotkb/G3MY23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYG1", "url": "https://www.uniprot.org/uniprotkb/G3MYG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYG1-1", "url": "https://www.uniprot.org/uniprotkb/G3MYG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0P4", "url": "https://www.uniprot.org/uniprotkb/G3N0P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0P4-1", "url": "https://www.uniprot.org/uniprotkb/G3N0P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0R1", "url": "https://www.uniprot.org/uniprotkb/G3N0R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0R1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2Z7", "url": "https://www.uniprot.org/uniprotkb/G3N2Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2Z7-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGFVFCRDCKEPYHEGDCGAVIEASGTVTQAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPRCQFQWCWNCGCEWNRACMGDHWFDV", "length": 460, "header": "tr|G3N2Z7-1|G3N2Z7_BOVIN Isoform 1 of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=2 CANONICAL=G3N2Z7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TGG9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGG9/entry", "sequence": { "sequence": "MKVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPRCQFQWCWNCGCEWNRACMGDHWFDV", "length": 431, "header": "tr|A0AAA9TGG9-1|G3N2Z7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=2 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 98111833, "end_pos": 96960261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112248.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112248.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095968.2", "url": "https://www.ensembl.org/id/ENSBTAP00000095968.2" } ] } }, { "isoform_ac": "A0AAA9TQT1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQT1/entry", "sequence": { "sequence": "MIVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGFVFCRDCKEPYHEGDCGAVIEASGTVTQAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPRCQFQWCWNCGCEWNRACMGDHWFDV", "length": 316, "header": "tr|A0AAA9TQT1-1|G3N2Z7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=1 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 98192491, "end_pos": 96960261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103253.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103253.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099671.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099671.1" } ] } }, { "isoform_ac": "A0AAA9U024-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U024/entry", "sequence": { "sequence": "MIVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGFVFCRDCKEPYHEGDCGAVIEASGTVTQAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPRCQFQWCWNCGCEWNRACMGDHWFDV", "length": 432, "header": "tr|A0AAA9U024-1|G3N2Z7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=1 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 98192491, "end_pos": 96960261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091511.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091511.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102917.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102917.1" } ] } }, { "isoform_ac": "F1MIV9-1", "url": "https://www.uniprot.org/uniprotkb/F1MIV9/entry", "sequence": { "sequence": "VFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVVQPVPAVRGGRVRAAARGRALPRPGLRGGAASRTGPAEGLLRAGPWPGLRGEYQP", "length": 338, "header": "tr|F1MIV9-1|G3N2Z7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=5 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 97955040, "end_pos": 97155314, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025286.8", "url": "https://www.ensembl.org/id/ENSBTAT00000025286.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025286.8", "url": "https://www.ensembl.org/id/ENSBTAP00000025286.8" } ] } }, { "isoform_ac": "G3MY23-1", "url": "https://www.uniprot.org/uniprotkb/G3MY23/entry", "sequence": { "sequence": "VFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGDSPGSPVVKTPCSTAGGTGSIPGWGTKILLRCMFVFCRDCKEPYHEGDCGAVIEASGTVTQAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGESGLTEERGCGGLSSEGGREVGIYKGFLAGELSAGALGPSGQGLNLSTHVKLLNLLNRKSSSVK", "length": 519, "header": "tr|G3MY23-1|G3MY23_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=2 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 97955040, "end_pos": 96966930, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065043.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065043.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054449.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054449.2" } ] } }, { "isoform_ac": "G3MYG1-1", "url": "https://www.uniprot.org/uniprotkb/G3MYG1/entry", "sequence": { "sequence": "MKVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGFVFCRDCKEPYHEGDCGAVIEASGTVTQAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPRCQFQWCWNCGCEWNRACMGDHWFDV", "length": 460, "header": "tr|G3MYG1-1|G3N2Z7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=4 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 98111833, "end_pos": 96960261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064521.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064521.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054593.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054593.4" } ] } }, { "isoform_ac": "G3N0P4-1", "url": "https://www.uniprot.org/uniprotkb/G3N0P4/entry", "sequence": { "sequence": "MKVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGFVFCRDCKEPYHEGDCGAVIEASGTVTQAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGC", "length": 425, "header": "tr|G3N0P4-1|G3N0P4_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=3 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 98111833, "end_pos": 96952333, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000062978.4", "url": "https://www.ensembl.org/id/ENSBTAT00000062978.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055410.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055410.3" } ] } }, { "isoform_ac": "G3N0R1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0R1/entry", "sequence": { "sequence": "MKVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVDS", "length": 287, "header": "tr|G3N0R1-1|G3N2Z7_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=3 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 98111833, "end_pos": 97286450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064741.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064741.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055427.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055427.3" } ] } }, { "isoform_ac": "G3N2Z7-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Z7/entry", "sequence": { "sequence": "MIVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRRKGPEGHSPRPAWGRSDREPESLTRVDLSSSMLPADSVGLAVILQDGEESGASSARRPAGRPTYNSFYVYCKGPCQGVQPGKLRVRCSTCQQATLTLAQGPSCWEDVLIPNRMSGECQSPNCPGTRAEFFFKCGAHPTSDKETSVALNLITTNSRDISCITCTDIRSPVLVFQCTHRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQLGGVLCPGPGCGAGLLPEPGQRKVSCEPGHGLGCGFVFCRDCKEPYHEGDCGAVIEASGTVTQAYRVNEKAAEQARWEEASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPRCQFQWCWNCGCEWNRACMGDHWFDV", "length": 460, "header": "tr|G3N2Z7-1|G3N2Z7_BOVIN Isoform 1 of E3 ubiquitin-protein ligase parkin OS=Bos taurus OX=9913 GN=PRKN PE=3 SV=2 CANONICAL=G3N2Z7-1" }, "locus": { "chromosome": "9", "start_pos": 98192491, "end_pos": 96960261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063967.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063967.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056268.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056268.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-5205685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5205685", "resource": "Reactome", "description": "PINK1-PRKN Mediated Mitophagy" }, { "id": "R-BTA-5675482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675482", "resource": "Reactome", "description": "Regulation of necroptotic cell death" }, { "id": "R-BTA-5689877", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689877", "resource": "Reactome", "description": "Josephin domain DUBs" }, { "id": "R-BTA-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9646399", "resource": "Reactome", "description": "Aggrephagy" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 57, "go_terms": [ { "name": "positive regulation of metabolic process", "id": "GO:0009893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009893", "evidence": [ { "database": "UniProtKB", "id": "G3N2Z7", "url": "https://www.uniprot.org/uniprotkb/G3N2Z7" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "G3N2Z7", "url": "https://www.uniprot.org/uniprotkb/G3N2Z7" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "G3N2Z7", "url": "https://www.uniprot.org/uniprotkb/G3N2Z7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": 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{ "id": "F6QVU1", "url": "https://alphafold.ebi.ac.uk/entry/F6QVU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45679:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45679:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVU1-1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFRLLVPLGLLCALLPLHHGAPGPDGTAPDPAHYSFSLTLIDALDTLLILGNVSEFQRVVEVLQDNVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYTIWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPDNFIHNNGSTFDAVITPYGECVLGAGGYIFNTEAHPIDPAALHCCRRLKEEQWEVEDLMREFYSLKRKRSRFQKKTMSSGPWEPPTGPGTFSSPENHEQAREKKPAKQKIPLLSCPSQPFTSKLALLGQVFLDSS", "length": 541, "header": "tr|F6QVU1-1|F6QVU1_BOVIN Isoform 1 of alpha-1,2-Mannosidase OS=Bos taurus OX=9913 GN=EDEM2 PE=3 SV=1 CANONICAL=F6QVU1-1" }, "isoforms": [ { "isoform_ac": "F6QVU1-1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1/entry", "sequence": { "sequence": "MLFRLLVPLGLLCALLPLHHGAPGPDGTAPDPAHYSFSLTLIDALDTLLILGNVSEFQRVVEVLQDNVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYTIWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPDNFIHNNGSTFDAVITPYGECVLGAGGYIFNTEAHPIDPAALHCCRRLKEEQWEVEDLMREFYSLKRKRSRFQKKTMSSGPWEPPTGPGTFSSPENHEQAREKKPAKQKIPLLSCPSQPFTSKLALLGQVFLDSS", "length": 541, "header": "tr|F6QVU1-1|F6QVU1_BOVIN Isoform 1 of alpha-1,2-Mannosidase OS=Bos taurus OX=9913 GN=EDEM2 PE=3 SV=1 CANONICAL=F6QVU1-1" }, "locus": { "chromosome": "13", "start_pos": 64420773, "end_pos": 64393668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004969.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004969.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004969.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004969.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" }, { "name": "endoplasmic reticulum quality control compartment", "id": "GO:0044322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044322", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" }, { "name": "endoplasmic reticulum mannose trimming", "id": "GO:1904380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904380", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" }, { "name": "positive regulation of retrograde protein transport, ER to cytosol", "id": "GO:1904154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904154", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "id": "GO:0004571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004571", "evidence": [ { "database": "UniProtKB", "id": "F6QVU1", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "F6QVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVU1" }, { "id": "PIRSR601382-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601382-2" } ], "binding_site_uniprot": 438, "amino_acid": "Thr", "chebi_lig_id": "CHEBI:29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 438, "end_pos": 438, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RI62-1", "uniprot_ac": "F6RI62", "uniprot_id": "F6RI62_BOVIN", "mass": { "chemical_mass": 80040.0, "monoisotopic_mass": 80040.0 }, "refseq": { "ac": "XP_005212522", "name": "semaphorin-4F isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212522" }, "gene_names": [ { "name": "SEMA4F", "type": "recommended", "evidence": [ { "id": "F6RI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ] }, { "name": "SEMA4F", "type": "synonym", "evidence": [ { "id": "XP_005212522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212522" } ] } ], "protein_names": [ { "name": "Semaphorin-4F", "type": "recommended", "evidence": [ { "id": "F6RI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RI62/entry#names_and_taxonomy" } ] }, { "name": "Semaphorin-W", "type": "synonym", "evidence": [ { "id": "F6RI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RI62/entry#names_and_taxonomy" } ] }, { "name": "semaphorin-4F isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005212522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212522" } ] } ], "function": [ { "annotation": "Probable cell surface receptor that regulates oligodendroglial precursor cell migration. Might also regulate differentiation of oligodendroglial precursor cells. Has growth cone collapse activity against retinal ganglion-cell axons.", "evidence": [ { "database": "UniProtKB", "id": "E1BF41", "url": "https://www.uniprot.org/uniprotkb/E1BF41#function" }, { "database": "UniProtKB", "id": "ARBA00058150", "url": "https://www.uniprot.org/uniprotkb/ARBA00058150#function" }, { "database": "UniProtKB", "id": "A0AAA9ST99", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST99#function" }, { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SEMA4F", "url": "https://www.uniprot.org/uniprotkb/F6RI62", "locus": { "chromosome": "11", "start_pos": 9961644, "end_pos": 9986241, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006989", "url": "https://www.ensembl.org/id/ENSBTAG00000006989" } ] } } ], "crossref": [ { "id": "F6RI62", "url": "https://alphafold.ebi.ac.uk/entry/F6RI62", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006989", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006989", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11261", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11261", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "530018", "url": "https://www.ncbi.nlm.nih.gov/gene/530018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:530018", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "APLAKCE", "url": "https://omabrowser.org/oma/group/APLAKCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BF41", "url": "https://www.orthodb.org/?gene=E1BF41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RI62", "url": "https://www.orthodb.org/?gene=F6RI62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005212522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212522", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9ST99", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST99-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2H4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2H4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF41", "url": "https://www.uniprot.org/uniprotkb/E1BF41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF41-1", "url": "https://www.uniprot.org/uniprotkb/E1BF41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RI62-1", "url": "https://www.uniprot.org/uniprotkb/F6RI62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGSVARLLPRLRPSGTSPLFLLLLLALLRGPVCGRVPHSVPRTSLPISEADSYLTRFTIPQTYNYSVLLVDPASHMLYVGARDTIFATSLPFSGEKPRRIDWMVPEAHRQNCRKKGKKEDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGALYAATVKNYLGTEPIISRAVGRAEDWVRTETLPSWLNAPAFVAAMALSPAEWGDEDGDDEIYFFFTEIARAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAILRPEGGAGTPVFYGIFSSQWEGAAISAVCSFRPQDIRTVLNGPFRELKHDCNRGLPVMDNDVPQPRPGECITNNMKLQQFGSSLFLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVPSLSGKEYDVLYLGTEDGHLHRAVQIGAQLSVLEDLALFPEPQPVENMKLYQNWLLVGSRTEVTQVNTANCGRLQSCSECILARDPACAWSVRLAACVAHPGEHGGLVQDIESADVSSLCPEEPGEHPVVFEVPVAAAAHVVLPCSPSSAWASCVWRQPSGVTALTRRQEGLEVVISPGAMGAYACECQEGGAARVVAAYSLVWGTPRGPLSQAHTIGAGLAGFFLGVLAASLTLLLIGRHQQRQRQRELLARDKVGLDLGVPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFPPPFLLDPCPSPAHIRLTGAPLATCDETSI", "length": 738, "header": "tr|F6RI62-1|F6RI62_BOVIN Isoform 1 of Semaphorin-4F OS=Bos taurus OX=9913 GN=SEMA4F PE=4 SV=1 CANONICAL=F6RI62-1" }, "isoforms": [ { "isoform_ac": "A0AAA9ST99-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST99/entry", "sequence": { "sequence": "MVTEEARTEVHDDAEEATVARVQIDWMVPEAHRQNCRKKGKKEDECHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGALYAATVKNYLGTEPIISRAVGRAEDWVRTETLPSWLNAPAFVAAMALSPAEWGDEDGDDEIYFFFTEIARAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAILRPEGGAGTPVFYGIFSSQWEGAAISAVCSFRPQDIRTVLNGPFRELKHDCNRGLPVMDNDVPQPRPGECITNNMKLQQFGSSLFLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVPSLSGKEYDVLYLGTEDGHLHRAVQIGAQLSVLEDLALFPEPQPVENMKLYQNWLLVGSRTEVTQVNTANCGRLQSCSECILARDPACAWSVRLAACVAHPGEHGGLVQDIESADVSSLCPEEPGEHPVVFEVPVAAAAHVVLPCSPSSAWASCVWRQPSGVTALTRRQEGLEVVISPGAMGAYACECQEGGAARVVAAYSLVWGTPRGPLSQAHTIGAGLAGFFLGVLAASLTLLLIGRHQQRQRQRELLARDKVGLDLGVPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFPPPFLLDPCPSPAHIRLTGAPLATCDETSI", "length": 694, "header": "tr|A0AAA9ST99-1|F6RI62_BOVIN Computationally mapped isoform of Semaphorin-4F OS=Bos taurus OX=9913 GN=SEMA4F PE=4 SV=1 CANONICAL=F6RI62-1" }, "locus": { "chromosome": "11", "start_pos": 9982845, "end_pos": 9963345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117790.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117790.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086278.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086278.1" } ] } }, { "isoform_ac": "A0AAA9T2H4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2H4/entry", "sequence": { "sequence": "MPGSVARLLPRLRPSGTSPLFLLLLLALLRGPVCGRVPHSVPRTSLPISEADSYLTRFTIPQTYNYSVLLVDPASHMLYVGARDTIFATSLPFSGEKPRRIDWMVPEAHRQNCRKKGKKEGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAILRPEGGAGTPVFYGIFSSQWEGAAISAVCSFRPQDIRTVLNGPFRELKHDCNRGLPVMDNDVPQPRPGECITNNMKLQQFGSSLFLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVPSLSGKEYDVLYLGTEDGHLHRAVQIGAQLSVLEDLALFPEPQPVENMKLYQNWLLVGSRTEVTQVNTANCGRLQSCSECILARDPACAWSVRLAACVAHPGEHGGLVQDIESADVSSLCPEEPGEHPVVFEVPVAAAAHVVLPCSPSSAWASCVWRQPSGVTALTRRQEGLEVVISPGAMGAYACECQEGGAARVVAAYSLVWGTPRGPLSQAHTIGAGLAGFFLGVLAASLTLLLIGRHQQRQRQRELLARDKVGLDLGVPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFPPPFLLDPCPSPAHIRLTGAPLATCDETSI", "length": 616, "header": "tr|A0AAA9T2H4-1|F6RI62_BOVIN Computationally mapped isoform of Semaphorin-4F OS=Bos taurus OX=9913 GN=SEMA4F PE=4 SV=1 CANONICAL=F6RI62-1" }, "locus": { "chromosome": "11", "start_pos": 9986160, "end_pos": 9963345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132451.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132451.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091931.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091931.1" } ] } }, { "isoform_ac": "E1BF41-1", "url": "https://www.uniprot.org/uniprotkb/E1BF41/entry", "sequence": { "sequence": "MPGSVARLLPRLRPSGTSPLFLLLLLALLRGPVCGRVPHSVPRTSLPISEADSYLTRFTIPQTYNYSVLLVDPASHMLYVGARDTIFATSLPFSGEKPRRIDWMVPEAHRQNCRKKGKKEDECHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGALYAATVKNYLGTEPIISRAVGRAEDWVRTETLPSWLNAPAFVAAMALSPAEWGDEDGDDEIYFFFTEIARAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAILRPEGGAGTPVFYGIFSSQWEGAAISAVCSFRPQDIRTVLNGPFRELKHDCNRGLPVMDNDVPQPRPGECITNNMKLQQFGSSLFLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVPSLSGKEYDVLYLGTEDGHLHRAVQIGAQLSVLEDLALFPEPQPVENMKLYQNWLLVGSRTEVTQVNTANCGRLQSCSECILARDPACAWSVRLAACVAHPGEHGGLVQDIESADVSSLCPEEPGEHPVVFEVPVAAAAHVVLPCSPSSAWASCVWRQPSGVTALTRRQEGLEVVISPGAMGAYACECQEGGAARVVAAYSLVWGTPRGPLSQAHTIGAGLAGFFLGVLAASLTLLLIGRHQQRQRQRELLARDKVGLDLGVPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFPPPFLLDPCPSPAHIRLTGAPLATCDETSI", "length": 771, "header": "tr|E1BF41-1|E1BF41_BOVIN Computationally mapped isoform of Semaphorin-4F OS=Bos taurus OX=9913 GN=SEMA4F PE=4 SV=1 CANONICAL=F6RI62-1" }, "locus": { "chromosome": "11", "start_pos": 9986160, "end_pos": 9963345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009186.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009186.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009186.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009186.5" } ] } }, { "isoform_ac": "F6RI62-1", "url": "https://www.uniprot.org/uniprotkb/F6RI62/entry", "sequence": { "sequence": "MPGSVARLLPRLRPSGTSPLFLLLLLALLRGPVCGRVPHSVPRTSLPISEADSYLTRFTIPQTYNYSVLLVDPASHMLYVGARDTIFATSLPFSGEKPRRIDWMVPEAHRQNCRKKGKKEDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGALYAATVKNYLGTEPIISRAVGRAEDWVRTETLPSWLNAPAFVAAMALSPAEWGDEDGDDEIYFFFTEIARAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAILRPEGGAGTPVFYGIFSSQWEGAAISAVCSFRPQDIRTVLNGPFRELKHDCNRGLPVMDNDVPQPRPGECITNNMKLQQFGSSLFLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVPSLSGKEYDVLYLGTEDGHLHRAVQIGAQLSVLEDLALFPEPQPVENMKLYQNWLLVGSRTEVTQVNTANCGRLQSCSECILARDPACAWSVRLAACVAHPGEHGGLVQDIESADVSSLCPEEPGEHPVVFEVPVAAAAHVVLPCSPSSAWASCVWRQPSGVTALTRRQEGLEVVISPGAMGAYACECQEGGAARVVAAYSLVWGTPRGPLSQAHTIGAGLAGFFLGVLAASLTLLLIGRHQQRQRQRELLARDKVGLDLGVPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFPPPFLLDPCPSPAHIRLTGAPLATCDETSI", "length": 738, "header": "tr|F6RI62-1|F6RI62_BOVIN Isoform 1 of Semaphorin-4F OS=Bos taurus OX=9913 GN=SEMA4F PE=4 SV=1 CANONICAL=F6RI62-1" }, "locus": { "chromosome": "11", "start_pos": 9986160, "end_pos": 9963345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056323.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056323.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050173.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050173.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:530018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530018", "resource": "KEGG Pathway" }, { "id": "R-BTA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AF71-1", "protein_name": "Ssemaphorin 4F", "gene_name": "SEMA4F", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLASVARPRPGLGLPRVLPFPLLLLMAVLNSPVSGRVPHSVPRTSLPISEADSYLTRFTIPQTYNYSVLLVDPASHTLYVGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKEDVSSFQQVESLESGRGKCPFEPAQRSAAVMAGGVLYAATVKNYLGTEPIISRAVGRAEDWIRTETLPSWLNAPAFVAATALSPAEWGDDDGDDEVYFFFTEISRAFDSYERVKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDMAILRPEPGAGTPVFYGIFSSQWEGAAISAVCSFRPQDIRTVLNGPFRELKHDCNRGLPVMDNDVPQPRPGECIANNMKFQQFGSSLFLPDRVLTFIRDHPLMDRPVFPADGHPLLVTTDTAYVRVVAHRVPSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPEPQPVENMKLYQNWLLLGSGTEVTQVNTTNCGRLQSCSECILARDPVCAWSGRLAACVAHEGDRGGLVQDIESADVSSLCPKEPGEHPVVFEVPVAAAAHVVLPCSPSSAWASCVWHQPSGVTALTPRQNGLEVALSPGAMGAYACECQEGGTARVVAAYSLVWGSQRGPPSRAHTVGAGLAGFFLGVLAASLTLLLIGRRQQRQRQRELLARDKVGLDLGVPASGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFPPPFLLDPCPSPAHIRLTGAPLATCDETSI", "length": 738 }, "evidence": [ { "id": "F6RI62", "url": "https://omabrowser.org/oma/group/F6RI62/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95754-1", "protein_name": "Semaphorin-4F", "gene_name": "SEMA4F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPASAARPRPGPGQPTASPFPLLLLAVLSGPVSGRVPRSVPRTSLPISEADSCLTRFAVPHTYNYSVLLVDPASHTLYVGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKEDECHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYAATVKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPAFVAAVALSPAEWGDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRPQDIRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPEPQPVENMKLYHSWLLVGSRTEVTQVNTTNCGRLQSCSECILAQDPVCAWSFRLDECVAHAGEHRGLVQDIESADVSSLCPKEPGERPVVFEVPVATAAHVVLPCSPSSAWASCVWHQPSGVTALTPRRDGLEVVVTPGAMGAYACECQEGGAAHVVAAYSLVWGSQRDAPSRAHTVGAGLAGFFLGILAASLTLILIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFSPPFLLDPCPSPAHIRLTGAPLATCDETSI", "length": 770 }, "evidence": [ { "id": "F6RI62", "url": "https://omabrowser.org/oma/group/F6RI62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z123-1", "protein_name": "Semaphorin-4F", "gene_name": "Sema4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLARAERPRPGPRPPPVSLFPPPSSLLLLLLAMLSAPVCGRVPRSVPRTSLPISEADSYLTRFAAPHTYNYSALLVDPASHTLYVGARDSIFALTLPFSGEKPRRIDWMVPETHRQNCRKKGKKEDECHNFIQILAIANASHLLTCGTFAFDPKCGVIDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYTATVKNFLGTEPIISRAVGRAEDWIRTETLSSWLNAPAFVAAMVLSPAEWGDEDGDDEIFFFFTETSRVLDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASGVLQDMTELRPQPGAGTPLFYGIFSSQWEGAAISAVCAFRPQDIRAVLNGPFRELKHDCNRGLPVMDNEVPQPRPGECITNNMKFQQFGSSLSLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPETQPVESMKLYHDWLLVGSHTEVTQVNTSNCGRLQSCSECILAQDPVCAWSFRLDACVAHAGEHRGMVQDIESADVSSLCPKEPGEHPVVFEVPVATVGHVVLPCSPSSAWASCVWHQPSGVTSLTPRRDGLEVVVTPGAMGAYACECQEGGAARVVAAYSLVWGSQRGPANRAHTVVGAGLVGFFLGVLAASLTLLLIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALGKRGSGFGGFPPPFLLDSCPSPAHIRLTGAPLATCDETSI", "length": 777 }, "evidence": [ { "id": "F6RI62", "url": "https://omabrowser.org/oma/group/F6RI62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z143-1", "protein_name": "Semaphorin-4F", "gene_name": "Sema4f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLARAERPRPGPRPPPVFPFPPPLSLLLLLAILSAPVCGRVPRSVPRTSLPISEADSYLTRFAASHTYNYSALLVDPASHTLYVGARDSIFALTLPFSGERPRRIDWMVPETHRQNCRKKGKKEDECHNFIQILAIVNASHLLTCGTFAFDPKCGVIDVSSFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYTATVKNFLGTEPIISRAVGRAEDWIRTETLSSWLNAPAFVAAMVLSPAEWGDEDGDDEIFFFFTETSRVLDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASGVLQAMAELRPQPGAGTPIFYGIFSSQWEGAAISAVCAFRPQDIRAVLNGPFRELKHDCNRGLPVMDNEVPQPRPGECIANNMKLQQFGSSLSLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPEPQPVESMKLYHDWLLVGSHTEVTQVNTSNCGRLQSCSECILAQDPVCAWSFRLDACVAHAGEHRGMVQDIESADVSSLCPKEPGEHPVVFEVPVATVGHVVLPCSPSSAWASCVWHQPSGVTALTPRRDGLEVVVTPGAMGAYACECQEGGAARVVAAYSLVWGSQRGPSNRAHTVVGAGLVGFLLGVLAASLTLLLIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALGKRGSGFGGFPPPFLLDSCPSPAHIRLTGAPLATCDETSI", "length": 776 }, "evidence": [ { "id": "F6RI62", "url": "https://omabrowser.org/oma/group/F6RI62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "neuropilin binding", "id": "GO:0038191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038191", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "F6RI62", "url": "https://www.uniprot.org/uniprotkb/F6RI62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RI62" }, { "id": "PS51004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sema", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 478, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"locus": { "chromosome": "5", "start_pos": 84787619, "end_pos": 84753414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140564.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140564.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104756.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104756.1" } ] } }, { "isoform_ac": "E1BMX0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMX0/entry", "sequence": { "sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCIIM", "length": 188, "header": "tr|E1BMX0-1|A0A3Q1LMP2_BOVIN Computationally mapped isoform of small monomeric GTPase OS=Bos taurus OX=9913 GN=KRAS PE=3 SV=4 CANONICAL=A0A3Q1LMP2-1" }, "locus": { "chromosome": "5", "start_pos": 84787619, "end_pos": 84753414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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189 }, "evidence": [ { "id": "A0A3Q1LMP2", "url": "https://omabrowser.org/oma/group/A0A3Q1LMP2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P01116-1", "protein_name": "GTPase KRas", "gene_name": "KRAS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM", "length": 189 }, "evidence": [ { "id": "A0A3Q1LMP2", "url": "https://omabrowser.org/oma/group/A0A3Q1LMP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P03967-1", "protein_name": "Ras-like protein rasD", "gene_name": "rasD", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": 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"database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", "E1BJA0-1", "A0A3Q1N147-1", "A0AAF6YME1-1", "F1MX39-1", "Q1RMJ6-1", "Q2HJ68-1", "Q2HJG3-1", "Q17QI8-1", "Q3SZA1-1", "A0ABI0NZ89-1", "A0ABI0P4Y3-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-BTA-1168636", "name": "p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-1168636", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1168636" } ] }, { "id": "R-BTA-1250383", "name": "RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N758-1", "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-1250383", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1250383" } ] }, { "id": "R-BTA-1306972", "name": "RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N758-1", "A0A3Q1LMP2-1", "A0AAA9SBR4-1" ], "evidence": [ { "id": "R-BTA-1306972", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1306972" } ] }, { "id": "R-BTA-1433471", "name": "Activation of RAS by p-KIT bound SOS1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "P43481-1" ], "evidence": [ { "id": "R-BTA-1433471", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1433471" } ] }, { "id": "R-BTA-170986", "name": "Ral-GDS binds to Ras-GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-170986", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170986" } ] }, { "id": "R-BTA-177938", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0A3Q1MHB0-1" ], "evidence": [ { "id": "R-BTA-177938", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-177938" } ] }, { "id": "R-BTA-177945", "name": "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0A3Q1MHB0-1" ], "evidence": [ { "id": "R-BTA-177945", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-177945" } ] }, { "id": "R-BTA-186834", "name": "SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MX49-1", "F1N759-1" ], "evidence": [ { "id": "R-BTA-186834", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-186834" } ] }, { "id": "R-BTA-210977", "name": "Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "Q06807-1" ], "evidence": [ { "id": "R-BTA-210977", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210977" } ] }, { "id": "R-BTA-2179407", "name": "SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0A3Q1MHB0-1" ], "evidence": [ { "id": "R-BTA-2179407", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2179407" } ] }, { "id": "R-BTA-2424477", "name": "SOS mediated nucleotide exchange of RAS (SHC)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-2424477", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2424477" } ] }, { "id": "R-BTA-392054", "name": "NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "E1BPA0-1", "A0JNB0-1" ], "evidence": [ { "id": "R-BTA-392054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-392054" } ] }, { "id": "R-BTA-5218845", "name": "p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-BTA-186833" ], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-5218845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5218845" } ] }, { "id": "R-BTA-5654392", "name": "Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LUE0-1", "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-5654392", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654392" } ] }, { "id": "R-BTA-5654402", "name": "Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MNW2-1" ], "evidence": [ { "id": "R-BTA-5654402", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654402" } ] }, { "id": "R-BTA-5654413", "name": "Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0AAA9TAT1-1" ], "evidence": [ { "id": "R-BTA-5654413", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654413" } ] }, { "id": "R-BTA-5654426", "name": "Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MN51-1" ], "evidence": [ { "id": "R-BTA-5654426", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654426" } ] }, { "id": "R-BTA-5654600", "name": "Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LUE0-1", "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-5654600", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654600" } ] }, { "id": "R-BTA-5654618", "name": "Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MNW2-1" ], "evidence": [ { "id": "R-BTA-5654618", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654618" } ] }, { "id": "R-BTA-5654647", "name": "Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0AAA9TAT1-1" ], "evidence": [ { "id": "R-BTA-5654647", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654647" } ] }, { "id": "R-BTA-5654663", "name": "Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MN51-1" ], "evidence": [ { "id": "R-BTA-5654663", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654663" } ] }, { "id": "R-BTA-5672950", "name": "Activator\" RAF:YWHAB dimer binds RAS:GTP\"", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5672950", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672950" } ] }, { "id": "R-BTA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LUE0-1", "F1N758-1", "A0AAA9SXH6-1", "E1BEL4-1", "A0A3Q1LMP2-1", "A0AAA9SBR4-1", "F1MN51-1", "Q3MHJ9-1", "Z4YHD9-1", "F1MX49-1", "F1MRU0-1", "Q06807-1", "Q2HJF7-1", "E1BPA0-1", "A0A3Q1MHB0-1", "P43481-1", "A0JNB0-1", "F1MS00-1", "A0ABI0P1V8-1", "F1N759-1", "F1MNW2-1", "A0AAA9TAT1-1" ], "evidence": [ { "id": "R-BTA-5672965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672965" } ] }, { "id": "R-BTA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MC61-1", "F1MAZ8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5672966", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672966" } ] }, { "id": "R-BTA-5672969", "name": "Phosphorylation of RAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0A3Q1LMP2-1", "Q3MHJ9-1", "Q2HJF7-1", "F1MAZ8-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5672969", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672969" } ] }, { "id": "R-BTA-5672972", "name": "MAP2Ks and MAPKs bind to the activated RAF complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5672972", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672972" } ] }, { "id": "R-BTA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5672973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672973" } ] }, { "id": "R-BTA-5672978", "name": "RAF phosphorylates MAP2K dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5672978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672978" } ] }, { "id": "R-BTA-5672980", "name": "Dissociation of RAS:RAF complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5672980", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672980" } ] }, { "id": "R-BTA-5674018", "name": "BRAP binds RAS:GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-5674018", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5674018" } ] }, { "id": "R-BTA-5674022", "name": "BRAP autoubiquitinates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-5674022", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5674022" } ] }, { "id": "R-BTA-5675417", "name": "PEBP1 binds activated RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5675417", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675417" } ] }, { "id": "R-BTA-5675431", "name": "PP2A dephosphorylates RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P67774-1", "Q0P594-1", "A0A3Q1LMP2-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5675431", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675431" } ] }, { "id": "R-BTA-5675433", "name": "PP5 dephosphorylates RAF1 S338", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1N719-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-5675433", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675433" } ] }, { "id": "R-BTA-8851827", "name": "RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "Z4YHD9-1" ], "evidence": [ { "id": "R-BTA-8851827", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8851827" } ] }, { "id": "R-BTA-8851877", "name": "RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "Z4YHD9-1" ], "evidence": [ { "id": "R-BTA-8851877", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8851877" } ] }, { "id": "R-BTA-8851899", "name": "RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "Z4YHD9-1" ], "evidence": [ { "id": "R-BTA-8851899", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8851899" } ] }, { "id": "R-BTA-8941613", "name": "Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MN51-1", "F1N339-1" ], "evidence": [ { "id": "R-BTA-8941613", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941613" } ] }, { "id": "R-BTA-8941618", "name": "Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1N339-1", "F1MNW2-1" ], "evidence": [ { "id": "R-BTA-8941618", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941618" } ] }, { "id": "R-BTA-8941623", "name": "Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LUE0-1", "A0A3Q1LMP2-1", "F1N339-1" ], "evidence": [ { "id": "R-BTA-8941623", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941623" } ] }, { "id": "R-BTA-8941628", "name": "Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1N339-1", "A0AAA9TAT1-1" ], "evidence": [ { "id": "R-BTA-8941628", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941628" } ] }, { "id": "R-BTA-8981353", "name": "RASA1 stimulates RAS GTPase activity", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-8981353", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8981353" } ] }, { "id": "R-BTA-8981355", "name": "RASA1 binds RAS:GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-8981355", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8981355" } ] }, { "id": "R-BTA-9607304", "name": "SOS1-mediated nucleotide exchange of RAS downstream of FLT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MRU0-1" ], "evidence": [ { "id": "R-BTA-9607304", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9607304" } ] }, { "id": "R-BTA-9632906", "name": "PRKCZ recruits RAS in response to estrogen stimulation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0AAA9S663-1" ], "evidence": [ { "id": "R-BTA-9632906", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9632906" } ] }, { "id": "R-BTA-9632910", "name": "ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "P46196-1", "A0AAA9S663-1" ], "evidence": [ { "id": "R-BTA-9632910", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9632910" } ] }, { "id": "R-BTA-9632918", "name": "PRKCZ stimulates RAS nucleotide exchange in response to estrogen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0AAA9S663-1" ], "evidence": [ { "id": "R-BTA-9632918", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9632918" } ] }, { "id": "R-BTA-9647977", "name": "ICMT methylates S-Farn RAS proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9647977", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9647977" } ] }, { "id": "R-BTA-9647978", "name": "pro-RAS proteins are farnesylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A0AAA9S4G1-1", "P49355-1" ], "evidence": [ { "id": "R-BTA-9647978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9647978" } ] }, { "id": "R-BTA-9647980", "name": "mature RAS proteins translocate to plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9647980", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9647980" } ] }, { "id": "R-BTA-9647982", "name": "S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "Q58DA8-1" ], "evidence": [ { "id": "R-BTA-9647982", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9647982" } ] }, { "id": "R-BTA-9647994", "name": "RAS proteins are depalmitoylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-8848337" ], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MYM8-1", "A5PKD9-1", "A0A3Q1M5Z8-1" ], "evidence": [ { "id": "R-BTA-9647994", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9647994" } ] }, { "id": "R-BTA-9647999", "name": "RCE1 cleaves S-Farn proRAS proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "A6H7A0-1" ], "evidence": [ { "id": "R-BTA-9647999", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9647999" } ] }, { "id": "R-BTA-9649732", "name": "Mature S-Farn-Me KRAS4B translocates to plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane, plasma membrane", "input_participant_list": [ "R-BTA-9649690" ], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9649732", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9649732" } ] }, { "id": "R-BTA-9649733", "name": "mature p21 RAS binds GDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9649733", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9649733" } ] }, { "id": "R-BTA-9649735", "name": "Intrinsic nucleotide exchange on RAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9649735", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9649735" } ] }, { "id": "R-BTA-9649736", "name": "RAS intrinsic GTPase activity hydrolyzes GTP to GDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9649736", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9649736" } ] }, { "id": "R-BTA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1", "F1MAZ8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-9653108", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9653108" } ] }, { "id": "R-BTA-9653503", "name": "KRAS4B is phosphorylated on serine 181", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-BTA-9647815" ], "output_participant_list": [ "R-BTA-9653482" ], "enzyme_list": [ "A0A3Q1LMP2-1", "A0AAA9TU12-1", "A0AAA9SK35-1" ], "evidence": [ { "id": "R-BTA-9653503", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9653503" } ] }, { "id": "R-BTA-9653585", "name": "S-Farn-Me KRAS4B binds calmodulin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9653585", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9653585" } ] }, { "id": "R-BTA-9653592", "name": "pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial outer membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-BTA-9653578" ], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9653592", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9653592" } ] }, { "id": "R-BTA-9653595", "name": "pS181-S-Farn-Me KRAS4B binds BCL2L1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9653595", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9653595" } ] }, { "id": "R-BTA-9654521", "name": "Calmodulin dissociates KRAS4B from the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9654521", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9654521" } ] }, { "id": "R-BTA-9654523", "name": "ARL2:GTP bind PDE6D on KRAS4B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9654523", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9654523" } ] }, { "id": "R-BTA-9654525", "name": "PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9654525", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9654525" } ] }, { "id": "R-BTA-9654533", "name": "KRAS4B recycles to the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMP2-1" ], "evidence": [ { "id": "R-BTA-9654533", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9654533" } ] }, { "id": "R-BTA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-9657599", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9657599" } ] }, { "id": "R-BTA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-9657603", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9657603" } ] }, { "id": "R-BTA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-9657606", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9657606" } ] }, { "id": "R-BTA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P63258-1", "A0A3Q1LMP2-1", "Q0VBZ0-1", "P46196-1", "P60712-1", "P61223-1", "P62833-1", "F1MAZ8-1", "F1MF36-1", "E1B8P9-1", "E1BIM8-1", "A0A3Q1LQP3-1", "A0AAA9T2F0-1" ], "evidence": [ { "id": "R-BTA-9657608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9657608" } ] }, { "id": "R-BTA-9658253", "name": "RAS:GTP binds PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P32871-1", "A0A3Q1LMP2-1", "F1MYM3-1" ], "evidence": [ { "id": "R-BTA-9658253", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9658253" } ] }, { "id": "R-BTA-9674816", "name": "p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-BTA-9674821" ], "output_participant_list": [ "R-BTA-9647915" ], "enzyme_list": [ "A0AAA9SXH6-1", "A0A3Q1LMP2-1", "F1MCX4-1", "F1MWN2-1", "F1N339-1", "A0A3Q1MHG9-1", "A0ABI0P1V8-1", "F1N261-1" ], "evidence": [ { "id": "R-BTA-9674816", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9674816" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8848337", "participant_name": "PALM(-) [cytosol]", "crossref": [ { "id": "ZINC000006072466", "database": "ZINC", "url": "" }, { "id": "7896", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-BTA-186833", "participant_name": "RASA1 [cytosol]", "crossref": [ { "id": "ENSBTAG00000009565", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000012583", "database": "ENSEMBL", "url": "" }, { "id": "33735", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000012583", "database": "ENSEMBL", "url": "" }, { "id": "F1N7N8", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-BTA-9647815", "participant_name": "KRAS [plasma membrane]", "crossref": [ { "id": "E1BMX0", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9647915", "participant_name": "KRAS [plasma membrane]", "crossref": [ { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "E1BMX0", "database": "UniProt", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9649690", "participant_name": "KRAS [endoplasmic reticulum membrane]", "crossref": [ { "id": "E1BMX0", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9653482", "participant_name": "phospho-KRAS [plasma membrane]", "crossref": [ { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" }, { "id": "E1BMX0", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-BTA-9653578", "participant_name": "phospho-KRAS [mitochondrial outer membrane]", "crossref": [ { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "E1BMX0", "database": "UniProt", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-9674821", "participant_name": "phospho-KRAS [plasma membrane]", "crossref": [ { "id": "E1BMX0", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T898", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LUE0", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B9", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] } ] }, { "uniprot_ac": "A0A3Q1M5Z8", "gene_name": "LYPLA1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A3Q1M5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Z8" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A3Q1M5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Z8" } ] } ] }, { "uniprot_ac": "A0A3Q1MDX0", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1MHB0", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHB0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHB0" } ] } ] }, { "uniprot_ac": "A0A3Q1MHG9", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] } ] }, { "uniprot_ac": "A0A3Q1N147", "gene_name": "RAB1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] } ] }, { "uniprot_ac": "A0A3Q1NCE9", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] } ] }, { "uniprot_ac": "A0A3Q1NEF8", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] } ] }, { "uniprot_ac": "A0A3S5ZPA2", "gene_name": "RAB40B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] } ] }, { "uniprot_ac": "A0AAA9S306", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] } ] }, { "uniprot_ac": "A0AAA9S4G1", "gene_name": "FNTA", "activity": [ { "ec_number": "2.5.1.58", "activity": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "A0AAA9S4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4G1" } ] }, { "ec_number": "2.5.1.59", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "A0AAA9S4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4G1" } ] }, { "ec_number": "2.5.1.58", "activity": "", "evidence": [ { "id": "A0AAA9S4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4G1" } ] }, { "ec_number": "2.5.1.59", "activity": "", "evidence": [ { "id": "A0AAA9S4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4G1" } ] } ] }, { "uniprot_ac": "A0AAA9S5W8", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9SBR4", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] } ] }, { "uniprot_ac": "A0AAA9SGM6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SLN0", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] } ] }, { "uniprot_ac": "A0AAA9SV95", "gene_name": "RAB34", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV95" } ] } ] }, { "uniprot_ac": "A0AAA9SVR8", "gene_name": "LOC789148", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR8" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T9T1", "gene_name": "ERAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9T9T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9T1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9T9T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9T1" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TES1", "gene_name": "RAB5C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TES1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9TES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TES1" } ] } ] }, { "uniprot_ac": "A0AAA9TNQ2", "gene_name": "RIT1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TNQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNQ2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9TNQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNQ2" } ] } ] }, { "uniprot_ac": "A0AAA9TS74", "gene_name": "RAB36", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TS74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9TS74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TWE6", "gene_name": "RAB35", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TWE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9TWE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ] } ] }, { "uniprot_ac": "A0AAF6YME1", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0AAF6YME1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YME1" } ] } ] }, { "uniprot_ac": "A0AAF6YXF5", "gene_name": "RAB19", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6YXF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXF5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAF6YXF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXF5" } ] } ] }, { "uniprot_ac": "A0AAF6Z672", "gene_name": "TUFM", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z672", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z672" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "A0AAF6Z672", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z672" } ] } ] }, { "uniprot_ac": "A0ABI0NND0", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0ABI0NND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ] } ] }, { "uniprot_ac": "A0ABI0NZ89", "gene_name": "LOC616304", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NZ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ89" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0ABI0NZ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ89" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0ABI0P4Y3", "gene_name": "LOC132344468", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P4Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4Y3" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "A0ABI0P4Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4Y3" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A4FUD1", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A4FUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD1" } ] } ] }, { "uniprot_ac": "A4FV54", "gene_name": "RAB8A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A4FV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV54" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A4FV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV54" } ] } ] }, { "uniprot_ac": "A5D7J5", "gene_name": "RHOU", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A5D7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7J5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A5D7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7J5" } ] } ] }, { "uniprot_ac": "A5PKD9", "gene_name": "ABHD17C", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A5PKD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKD9" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A5PKD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKD9" } ] } ] }, { "uniprot_ac": "A6H7A0", "gene_name": "RCE1", "activity": [ { "ec_number": "3.4.26.1", "activity": "Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.", "evidence": [ { "id": "A6H7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H7A0" } ] }, { "ec_number": "3.4.26.1", "activity": "", "evidence": [ { "id": "A6H7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H7A0" } ] } ] }, { "uniprot_ac": "A6H7F2", "gene_name": "GPN2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A6H7F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H7F2" } ] } ] }, { "uniprot_ac": "A6H7I5", "gene_name": "DNM2", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A6H7I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H7I5" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A6H7I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H7I5" } ] } ] }, { "uniprot_ac": "A6QLJ3", "gene_name": "GUF1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A6QLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ3" } ] } ] }, { "uniprot_ac": "A6QNM2", "gene_name": "GFM2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A6QNM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QNM2" } ] } ] }, { "uniprot_ac": "A6QP66", "gene_name": "RERGL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A6QP66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QP66" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A6QP66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QP66" } ] } ] }, { "uniprot_ac": "A6QR46", "gene_name": "RAB6B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A6QR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR46" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A6QR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR46" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJA0", "gene_name": "RAB33A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "E1BJA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "E1BJA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MHP4", "gene_name": "RAB22A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1MHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHP4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1MHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHP4" } ] } ] }, { "uniprot_ac": "F1MM29", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1MM29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM29" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1MM29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM29" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNI4", "gene_name": "RAB5B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1MNI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNI4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1MNI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNI4" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MX39", "gene_name": "RAB42", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1MX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX39" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1MX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX39" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYM8", "gene_name": "ABHD17A", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "F1MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM8" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "F1MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM8" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N2J9", "gene_name": "RAB8B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1N2J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2J9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1N2J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2J9" } ] } ] }, { "uniprot_ac": "F1N339", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] } ] }, { "uniprot_ac": "F1N6Y7", "gene_name": "EIF5B", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1N6Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y7" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "F1N6Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y7" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N7V2", "gene_name": "RAB17", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1N7V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7V2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1N7V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7V2" } ] } ] }, { "uniprot_ac": "F2Z4D5", "gene_name": "RAB11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F2Z4D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4D5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F2Z4D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4D5" } ] } ] }, { "uniprot_ac": "F6Q1G9", "gene_name": "RAB24", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F6Q1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F6Q1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ] } ] }, { "uniprot_ac": "G3MYK6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "G3MYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYK6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "G3MYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYK6" } ] } ] }, { "uniprot_ac": "G3N1U2", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "G3N1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1U2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "G3N1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1U2" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P04695", "gene_name": "GNAT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P04695", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04695" } ] } ] }, { "uniprot_ac": "P04896", "gene_name": "GNAS", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P04896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04896" } ] } ] }, { "uniprot_ac": "P08239", "gene_name": "GNAO1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P08239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08239" } ] } ] }, { "uniprot_ac": "P10948", "gene_name": "RAB3B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P10948", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10948" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P10948", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10948" } ] } ] }, { "uniprot_ac": "P10949", "gene_name": "RAB3C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P10949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10949" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P10949", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10949" } ] } ] }, { "uniprot_ac": "P11023", "gene_name": "RAB3A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P11023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11023" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P11023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11023" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P49355", "gene_name": "FNTB", "activity": [ { "ec_number": "2.5.1.58", "activity": "L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "P49355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49355" } ] }, { "ec_number": "2.5.1.58", "activity": "", "evidence": [ { "id": "P49355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49355" } ] } ] }, { "uniprot_ac": "P49410", "gene_name": "TUFM", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P49410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49410" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "P49410", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49410" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": 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"activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P81947", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81947" } ] } ] }, { "uniprot_ac": "P81948", "gene_name": "TUBA4A", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P81948", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P81948" } ] } ] }, { "uniprot_ac": "P82922", "gene_name": "DAP3", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P82922", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82922" } ] } ] }, { "uniprot_ac": "P84080", "gene_name": "ARF1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P84080", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P84080" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P84080", "database": "UniProtKB", "url": 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}, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q08E00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E00" } ] } ] }, { "uniprot_ac": "Q0IIG7", "gene_name": "RAB5A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q0IIG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIG7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q0IIG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIG7" } ] } ] }, { "uniprot_ac": "Q0IIG8", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q0IIG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIG8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q0IIG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIG8" } ] } ] }, { "uniprot_ac": "Q0P594", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0P594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P594" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0P594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P594" } ] } ] }, { "uniprot_ac": "Q0P5E2", "gene_name": "GPN3", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q0P5E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5E2" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q0VCJ7", "gene_name": "RERG", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q0VCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCJ7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q0VCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCJ7" } ] } ] }, { "uniprot_ac": "Q17QB7", "gene_name": "RAB30", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q17QB7", "database": "UniProtKB", "url": 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{ "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q1RMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMJ6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q1RMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMJ6" } ] } ] }, { "uniprot_ac": "Q1RMR4", "gene_name": "RAB15", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q1RMR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q1RMR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMR4" } ] } ] }, { "uniprot_ac": "Q27957", "gene_name": "TPPP", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q27957", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27957" } ] } ] }, { "uniprot_ac": 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "K7DXW5-1", "uniprot_ac": "K7DXW5", "uniprot_id": "K7DXW5_BOVIN", "mass": { "chemical_mass": 119322.0, "monoisotopic_mass": 119322.0 }, "refseq": {}, "gene_names": [ { "name": "ZRANB3", "type": "recommended", "evidence": [ { "id": "K7DXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ] } ], "protein_names": [ { "name": "DNA annealing helicase and endonuclease ZRANB3", "type": "recommended", "evidence": [ { "id": "K7DXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/K7DXW5/entry#names_and_taxonomy" } ] }, { "name": "Annealing helicase 2", "type": "synonym", "evidence": [ { "id": "K7DXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/K7DXW5/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger Ran-binding domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "K7DXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/K7DXW5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LYC7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYC7#function" }, { "database": "UniProtKB", "id": "ARBA00056012", "url": "https://www.uniprot.org/uniprotkb/ARBA00056012#function" }, { "database": "UniProtKB", "id": "A0A3Q1MUB4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUB4#function" }, { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZRANB3", "url": "https://www.uniprot.org/uniprotkb/K7DXW5", "locus": { "chromosome": "2", "start_pos": 62108563, "end_pos": 61800423, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000026842", "url": "https://www.ensembl.org/id/ENSBTAG00000026842" } ] } } ], "crossref": [ { "id": "K7DXW5", "url": "https://alphafold.ebi.ac.uk/entry/K7DXW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000026842", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026842", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00085", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00085", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18010", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18010", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "K7DXW5", "url": "https://www.orthodb.org/?gene=K7DXW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45766:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45766:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01844", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01844", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYC7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUB4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "K7DXW5-1", "url": "https://www.uniprot.org/uniprotkb/K7DXW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRGHNIKKSLTPQISCSTSESYKQLDFLPDKLRAKLLPFQKDGITFALRRDGRCMVADEMGLGKTVQAIGIAYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELSPEEINVIQNKTDVGRISTSKVTVLGYGLLTTDAETLIDALNNQNFKVVIVDESHYMKSRSATRSRILLPIVQKAKRAILLTGTPALGRPEELFMQIEALFPQKFGTWTEYAKRYCNAHVRYFGRRSQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKIRQRIPFDLPSAAAKELNSSFEEWEKLMRDPYSGATETVMGLITRMFKQTAIAKAGAVKDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIENKTRYIRIDGSVPSSERIHLVNQFQKDPETRVAILSIQAAGQGLTFTAATHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGTLDTLMWGMLNRKAQVTGSTLNGRKEKLQAEEGDKEKWDFLQFAEAWTPNERSEELRDEMLFTHFEKEKQRDIRSFFLPNAKKRQLETSCDESRVSQEKNTIVPADPVKTATRGDESDLEPEAKKLKSVAIDDPCRPPEEQPCRPGQAEALLTFGICKAKAQATTPAFCGEGWQCAFCTYINNSVLPYCEMCENPRGGADSLNQTQNKNKNEKDDSQDTSKKIQTSSDGEKQVLAHSTPEPLAKSKEEISTTESEDRLTPQPGDEQLKNWPVYDTLMFCASKNTDRIHVYTKDGNQMNCNFIPLDIKLDLWEDLPASFQLKQNRSLILRFVREWSSLTAMKQKIIKKSGQLFRSPVLALEEIAKQQTKQNSTKRYITKEDVAAASMDKVKNDGGHVRLITKGPKPGDPSTKEFLEGGECVPFLNPCTAQGDLILKASTSKGYLQAVDNEGNPLCLRCQQPTCQTKQERKADAWDSRFCSLKCQEEFWIRSNNSYLRAKVFEIEHGVCQLCNLNAQELFLRLRDAPKSQRKSLLDATWTSKLPLEQLNEMIRSPGEGHFWQVDHIKPVSGGGGQCSLDNLQTLCTVCHRERTAQQAKERSQLSW", "length": 1052, "header": "tr|K7DXW5-1|K7DXW5_BOVIN Isoform 1 of DNA annealing helicase and endonuclease ZRANB3 OS=Bos taurus OX=9913 GN=ZRANB3 PE=3 SV=3 CANONICAL=K7DXW5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVH6/entry", "sequence": { "sequence": "MSRGHNIKKSLTPQISCSTSESYKQLDFLPDKLRAKLLPFQKDGITFALRRDGRCMVADEMGLGKTVQAIGIAYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELSPEEINVIQNKTDVGRISTSKVTVLGYGLLTTDAETLIDALNNQNFKVVIVDESHYMKSRSATRSRILLPIVQKAKRAILLTGTPALGRPEELFMQIEALFPQKFGTWTEYAKRYCNAHVRYFGRRSQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKIRQRIPFDLPSAAAKELNSSFEEWEKLMRDPYSGATETVMGLITRMFKQTAIAKTRYIRIDGSVPSSERIHLVNQFQKDPETRVAILSIQAAGQGLTFTAATHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGTLDTLMWGMLNRKAQVTGSTLNGRKEKLQAEEGDKEKWDFLQFAEAWTPNERSEELRDEMLFTHFEKEKQRDIRSFFLPNAKKRQLETSCDESRVSQEKNTIVPADPVKTATRGDESDLEPEAKKLKSVAIDDPCRPPEEQPCRPGQAEALLTFGICKAKAQATTPAFCGEGWQCAFCTYINNSVLPYCEMCENPRGGADSLNQTQNKNKNEKDDSQDTSKKIQTSSDGEKQVLAHSTPEPLAKSKEEISTTESEDRLTPQPGDEQLKNWPVYDTLMFCASKNTDRIHVYTKDGNQMNCNFIPLDIKLDLWEDLPASFQLKQNRSLILRFVREWSSLTAMKQKIIKKSGQLFRSPVLALEEIAKQQTKQNSTKRYITKEDVAAASMDKVKNDGGHVRLITKGPKPGDPSTKEFLEGGECVPFLNPCTAQGDLILKASTSKGYLQAVDNEGNPLCLRCQQPTCQTKQERKADAWDSRFCSLKCQEEFWIRSNNSYLRAKVFEIEHGVCQLCNLNAQELFLRLRDAPKSQRKSLLDATWTSKLPLEQLNEMIRSPGEGHFWQVDHIKPVSGGGGQCSLDNLQTLCTVCHRERTAQQAKERSQVRRQSLASNHGSDITRFLVKK", "length": 1030, "header": "tr|A0A3Q1LVH6-1|K7DXW5_BOVIN Computationally mapped isoform of DNA annealing helicase and endonuclease ZRANB3 OS=Bos taurus OX=9913 GN=ZRANB3 PE=3 SV=2 CANONICAL=K7DXW5-1" }, "locus": { "chromosome": "2", "start_pos": 62103604, "end_pos": 61831630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082650.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082650.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059308.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059308.2" } ] } }, { "isoform_ac": "A0A3Q1LYC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYC7/entry", "sequence": { "sequence": "MSRGHNIKKSLTPQISCSTSESYKQLDFLPDKLRAKLLPFQKDGITFALRRDGRCMVADEMGLGKTVQAIGIAYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELSPEEINVIQNKTDVGRISTSKVTVLGYGLLTTDAETLIDALNNQNFKVVIVDESHYMKSRSATRSRILLPIVQKAKRAILLTGTPALGRPEELFMQIEALFPQKFGTWTEYAKRYCNAHVRYFGRRSQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKIRQRIPFDLPSAAAKELNSSFEEWEKLMRDPYSGATETVMGLITRMFKQTAIAKAGAVKDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIENKTRYIRIDGSVPSSERIHLVNQFQKDPETRVAILSIQAAGQAQVTGSTLNGRKEKLQAEEGDKEKWDFLQFAEAWTPNERSEELRDEMLFTHFEKEKQRDIRSFFLPNAKKRQLETSCDESRVSQEKNTIVPADPVKTATRGDESDLEPEAKKLKSVAIDDPCRPPEEQPCRPGQAEALLTFGICKAKAQATTPAFCGEGWQCAFCTYINNSVLPYCEMCENPRGGADSLNQTQNKNKNEKDDSQDTSKKIQTSSDGEKQVLAHSTPEPLAKSKEEISTTESEDRLTPQPGDEQLKNWPVYDTLMFCASKNTDRIHVYTKDGNQMNCNFIPLDIKLDLWEDLPASFQLKQNRSLILRFVREWSSLTAMKQKIIKKSGQLFRSPVLALEEIAKQQTKQNSTKRYITKEDVAAASMDKVKNDGGHVRLITKGPKPGDPSTKEFLEGGECVPFLNPCTAQGDLILKASTSKGYLQAVDNEGNPLCLRCQQPTCQTKQERKADAWDSRFCSLKCQEEFWIRSNNSYLRAKVFEIEHGVCQLCNLNAQELFLRLRDAPKSQRKSLLDATWTSKLPLEQLNEMIRSPGEGHFWQVDHIKPVSGGGGQCSLDNLQTLCTVCHRERTAQQAKERSQVRRQSLASNHGSDITRFLVKK", "length": 1010, "header": "tr|A0A3Q1LYC7-1|A0A3Q1LYC7_BOVIN Computationally mapped isoform of DNA annealing helicase and endonuclease ZRANB3 OS=Bos taurus OX=9913 GN=ZRANB3 PE=3 SV=2 CANONICAL=K7DXW5-1" }, "locus": { "chromosome": "2", "start_pos": 62103604, "end_pos": 61831630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073311.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073311.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062570.3", "url": "https://www.ensembl.org/id/ENSBTAP00000062570.3" } ] } }, { "isoform_ac": "A0A3Q1MAW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAW7/entry", "sequence": { "sequence": "MSRGHNIKKSLTPQISCSTSESYKQLDFLPDKLRAKLLPFQKDGITFALRRDGRCMVADEMGLGKTVQAIGIAYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELSPEEINVIQNKTDVGRISTSKVTVLGYGLLTTDAETLIDALNNQNFKVVIVDESHYMKSRSATRSRILLPIVQKAKRAILLTGTPALGRPEELFMQIEALFPQKFGTWTEYAKRYCNAHVRYFGRRSQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKIRQRIPFDLPSAAAKELNSSFEEWEKLMRDPYSGATETVMGLITRMFKQTAIAKAGAVKDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIENKTRYIRIDGSVPSSERIHLVNQFQKDPETRVAILSIQAAGQAQVTGSTLNGRKEKLQAEEGDKEKWDFLQFAEAWTPNERSEELRDEMLFTHFEKEKQRDIRSFFLPNAKKRQLETSCDESRVSQEKNTIVPADPVKTATRGDESDLEPEAKKLKSVAIDDPCRPPEEQPCRPGQAKAQATTPAFCGEGWQCAFCTYINNSVLPYCEMCENPRGGADSLNQTQNKNKNEKDDSQDTSKKIQTSSDGEKQVLAHSTPEPLAKSKEEISTTESEDRLTPQPGDEQLKNWPVYDTLMFCASKNTDRIHVYTKDGNQMNCNFIPLDIKLDLWEDLPASFQLKQNRSLILRFVREWSSLTAMKQKIIKKSGQLFRSPVLALEEIAKQQTKQNSTKRYITKEDVAAASMDKVKNDGGHVRLITKGPKPGDPSTKEFLEGGECVPFLNPCTAQGDLILKASTSKGYLQAVDNEGNPLCLRCQQPTCQTKQERKADAWDSRFCSLKCQEEFWIRSNNSYLRAKVFEIEHGVCQLCNLNAQELFLRLRDAPKSQRKSLLDATWTSKLPLEQLNEMIRSPGEGHFWQVDHIKPVSGGGGQCSLDNLQTLCTVCHRERTAQQAKERSQVRRQSLASNHGSDITRFLVKK", "length": 999, "header": "tr|A0A3Q1MAW7-1|K7DXW5_BOVIN Computationally mapped isoform of DNA annealing helicase and endonuclease ZRANB3 OS=Bos taurus OX=9913 GN=ZRANB3 PE=3 SV=3 CANONICAL=K7DXW5-1" }, "locus": { "chromosome": "2", "start_pos": 62103604, "end_pos": 61831630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082407.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082407.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067396.3", "url": "https://www.ensembl.org/id/ENSBTAP00000067396.3" } ] } }, { "isoform_ac": "A0A3Q1MUB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUB4/entry", "sequence": { "sequence": "MSRGHNIKKSLTPQISCSTSESYKQLDFLPDKLRAKLLPFQKDGITFALRRDGRCMVADEMGLGKTVQAIGIAYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELSPEEINVIQNKTDVGRISTSKVTVLGYGLLTTDAETLIDALNNQNFKVVIVDESHYMKSRSATRSRILLPIVQKAKRAILLTGTPALGRPEELFMQIEALFPQKFGTWTEYAKRYCNAHVRYFGRRSQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKIRQRIPFDLPSAAAKELNSSFEEWEKLMRDPYSGATETVMGLITRMFKQTAIAKAGAVKDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIENKTRYIRIDGSVPSSERIHLVNQFQKDPETRVAILSIQAAGQGLTFTAATHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGTLDTLMWGMLNRKAQVTGSTLNGRKEKLQAEEGDKEKWDFLQFAEAWTPNERSEELRDEMLFTHFEKEKQRDIRSFFLPNAKKRQLETSCDESRVSQEKNTIVPADPVKTATRGDESDLEPEAKKLKSVAIDDPCRPPEEQPCRPGQAEALLTFGICKAKAQATTPAFCGEGWQCAFCTYINNSVLPYCEMCENPRGGAEQLKNWPVYDTLMFCASKNTDRIHVYTKDGNQMNCNFIPLDIKLDLWEDLPASFQLKQNRSLILRFVREWSSLTAMKQKIIKKSGQLFRSPVLALEEIAKQQTKQNSTKRYITKEDVAAASMDKVKNDGGHVRLITKGPKPGDPSTKEFLEGGECVPFLNPCTAQGDLILKASTSKGYLQAVDNEGNPLCLRCQQPTCQTKQERKADAWDSRFCSLKCQEEFWIRSNNSYLRAKVFEIEHGVCQLCNLNAQELFLRLRDAPKSQRKSLLDATWTSKLPLEQLNEMIRSPGEGHFWQVDHIKPVSGGGGQCSLDNLQTLCTVCHRERTAQQAKERSQVRRQSLASNHGSDITRFLVKK", "length": 1005, "header": "tr|A0A3Q1MUB4-1|K7DXW5_BOVIN Computationally mapped isoform of DNA annealing helicase and endonuclease ZRANB3 OS=Bos taurus OX=9913 GN=ZRANB3 PE=3 SV=2 CANONICAL=K7DXW5-1" }, "locus": { "chromosome": "2", "start_pos": 62103604, "end_pos": 61831630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072233.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072233.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074134.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074134.2" } ] } }, { "isoform_ac": "K7DXW5-1", "url": "https://www.uniprot.org/uniprotkb/K7DXW5/entry", "sequence": { "sequence": "MSRGHNIKKSLTPQISCSTSESYKQLDFLPDKLRAKLLPFQKDGITFALRRDGRCMVADEMGLGKTVQAIGIAYFYKEEWPLLIVVPSSLRYPWTEEIEKWIPELSPEEINVIQNKTDVGRISTSKVTVLGYGLLTTDAETLIDALNNQNFKVVIVDESHYMKSRSATRSRILLPIVQKAKRAILLTGTPALGRPEELFMQIEALFPQKFGTWTEYAKRYCNAHVRYFGRRSQWDCRGASNLNELHQLLSDIMIRRLKTEVLTQLPPKIRQRIPFDLPSAAAKELNSSFEEWEKLMRDPYSGATETVMGLITRMFKQTAIAKAGAVKDYIKMMLQNDSLKFLVFAHHLSMLQACTEAVIENKTRYIRIDGSVPSSERIHLVNQFQKDPETRVAILSIQAAGQGLTFTAATHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGTLDTLMWGMLNRKAQVTGSTLNGRKEKLQAEEGDKEKWDFLQFAEAWTPNERSEELRDEMLFTHFEKEKQRDIRSFFLPNAKKRQLETSCDESRVSQEKNTIVPADPVKTATRGDESDLEPEAKKLKSVAIDDPCRPPEEQPCRPGQAEALLTFGICKAKAQATTPAFCGEGWQCAFCTYINNSVLPYCEMCENPRGGADSLNQTQNKNKNEKDDSQDTSKKIQTSSDGEKQVLAHSTPEPLAKSKEEISTTESEDRLTPQPGDEQLKNWPVYDTLMFCASKNTDRIHVYTKDGNQMNCNFIPLDIKLDLWEDLPASFQLKQNRSLILRFVREWSSLTAMKQKIIKKSGQLFRSPVLALEEIAKQQTKQNSTKRYITKEDVAAASMDKVKNDGGHVRLITKGPKPGDPSTKEFLEGGECVPFLNPCTAQGDLILKASTSKGYLQAVDNEGNPLCLRCQQPTCQTKQERKADAWDSRFCSLKCQEEFWIRSNNSYLRAKVFEIEHGVCQLCNLNAQELFLRLRDAPKSQRKSLLDATWTSKLPLEQLNEMIRSPGEGHFWQVDHIKPVSGGGGQCSLDNLQTLCTVCHRERTAQQAKERSQLSW", "length": 1052, "header": "tr|K7DXW5-1|K7DXW5_BOVIN Isoform 1 of DNA annealing helicase and endonuclease ZRANB3 OS=Bos taurus OX=9913 GN=ZRANB3 PE=3 SV=3 CANONICAL=K7DXW5-1" }, "locus": { "chromosome": "2", "start_pos": 62108308, "end_pos": 61831630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038374.7", "url": "https://www.ensembl.org/id/ENSBTAT00000038374.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038188.6", "url": "https://www.ensembl.org/id/ENSBTAP00000038188.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "ATP-dependent DNA/DNA annealing activity", "id": "GO:0036310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036310", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" }, { "name": "replication fork reversal", "id": "GO:0071932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071932", "evidence": [ { "database": "UniProtKB", "id": "K7DXW5", "url": "https://www.uniprot.org/uniprotkb/K7DXW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], 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"Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", 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"id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": 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} ] } ] }, { "uniprot_ac": "A0A3Q1M7R9", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDD8", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": 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"activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] } ] }, { "uniprot_ac": "A0AAA9RUK3", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] } ] }, { "uniprot_ac": "A0AAA9RXI8", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] } ] }, { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9SPF3", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] } ] }, { "uniprot_ac": "A0AAA9STQ6", "gene_name": "G3BP1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": 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"activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6Z733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] } ] }, { "uniprot_ac": "A0ABI0NSA6", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ] } ] }, { "uniprot_ac": "A0ABI0NX25", "gene_name": "RIGI", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] } ] }, { "uniprot_ac": "A0ABI0NXS3", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ] } ] }, { "uniprot_ac": "A0ABI0P204", "gene_name": "LOC112446470", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] } ] }, { "uniprot_ac": "A4FUD9", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] } ] }, { "uniprot_ac": "A4K436", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A4K436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4K436" } ] } ] }, { "uniprot_ac": "A5D7C1", "gene_name": "DDX52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP 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"uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP 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"F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": 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"length": 1192, "header": "tr|A0A3Q1LK20-1|A0A3Q1LK20_BOVIN Isoform 1 of Metabotropic glutamate receptor 1 OS=Bos taurus OX=9913 GN=GRM1 PE=3 SV=1 CANONICAL=A0A3Q1LK20-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20/entry", "sequence": { "sequence": "MVRFLLVFFPTIFLEMTLLPRGPGRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDDRDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHILENPNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHQALCPGHVGLCDAMKPIDGSKLLEFLIKSTFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIVFSCLGILVTMFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVITLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTLLSIFRRKKPGAGNANSNGKSVSWSEPGGRQVPKGQHMWHRLSVHVKANETACNQTAVIKPLTKSYQGSGKSLTFSDTSTKTLYNVEEEDAQPVGFSPPSSPSRAAPRRVPTAASTPPLPPHLTAEETPLFLAEPAIPKGLPAPLQQPPLPQKSFLDQLQGVVNNFSAGIPDFSSVLAVPGAAGNGGRSLFPPPAPPQHLPLLPLPLSPFAEEPASPPGEDDDEDDSERFKLLQEYLSEREGNTEEDELEEEEEEGDLPAPSKPTPEASPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL", "length": 1192, "header": "tr|A0A3Q1LK20-1|A0A3Q1LK20_BOVIN Isoform 1 of Metabotropic glutamate receptor 1 OS=Bos taurus OX=9913 GN=GRM1 PE=3 SV=1 CANONICAL=A0A3Q1LK20-1" }, "locus": { "chromosome": "9", "start_pos": 83712961, "end_pos": 83289218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085376.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085376.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056935.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056935.1" } ] } }, { "isoform_ac": "F1MDE0-1", "url": "https://www.uniprot.org/uniprotkb/F1MDE0/entry", "sequence": { "sequence": "MVRFLLVFFPTIFLEMTLLPRGPGRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDDRDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHILENPNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHQALCPGHVGLCDAMKPIDGSKLLEFLIKSTFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIVFSCLGILVTMFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVITLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTLLSIFRRKKPGAGNAKKRQPEFSPTSQCPSAHVQL", "length": 906, "header": "tr|F1MDE0-1|A0A3Q1LK20_BOVIN Computationally mapped isoform of Metabotropic glutamate receptor 1 OS=Bos taurus OX=9913 GN=GRM1 PE=3 SV=4 CANONICAL=A0A3Q1LK20-1" }, "locus": { "chromosome": "9", "start_pos": 83704487, "end_pos": 83289218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061121.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061121.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053724.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053724.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540485", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540485", "resource": "KEGG Pathway" }, { "id": "R-BTA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-BTA-420499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-420499", "resource": "Reactome", "description": "Class C/3 (Metabotropic glutamate/pheromone receptors)" }, { "id": "R-BTA-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A3Q1LK20", "url": "https://omabrowser.org/oma/group/A0A3Q1LK20/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287AUS4-1", "protein_name": "Metabotropic glutamate receptor 1", "gene_name": "GRM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRLLLLFFPAVFLEMSLFPRGPGGKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHILENPNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSTFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGGRQVPKGQHMWHRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDTSTKTLYNLEEEDAQPVGFSPPSSPSMVMHRRVPTAASTPPLPPRLTAEETPLFLADPAIPKGLPPPLQQPPPLPQPQPQKALLDQLQGVVNNFSTGIPDFNAVLAVPGGPGNGVRSLFPPPAPPQHLQMLPLQLSTFGEEPASPPAEDDDEDDSERFKLLQEYVYEREGNTEEDELDEEEEDLQAASKPTLEDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL", "length": 1195 }, "evidence": [ { "id": "A0A3Q1LK20", "url": "https://omabrowser.org/oma/group/A0A3Q1LK20/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1NBM2-1", "protein_name": "Metabotropic glutamate receptor 1", "gene_name": "GRM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTAVLPLVLPALLLAGAALPPAAASAQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDDREGGGRCLSDSQPQPPGRLRKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGILIAMRRLGVLGEFLLIGSDGWADRDEVIEGYEQEANGGITIKLQSPEVLSFDDYYLKLRLDTNTRNPWFPEFWQHRFQCRIPGHPLENPNFQKNCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHSLCPGHVGLCDAMKPIDGSKLLEFLLKSTFIGVSGEEVWFDEKGDAPGRYDIMNLQYIEPNRYDYVLIGTWHEGVLNIDDYRIQMNKSGMVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEFVQDEFTCKACELGWWPNAELTGCEPIPVKYLQWSNIESIVAVVFSCLGILVTMFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTISCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIASILISVQLTLVVTLIILEPPMPILSYPSIKEVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKAPCKSNTFLNIFRRKKPGAGNPNSNGKSVSWSEPGGRQASKGEHMWHRLSVHVKNQETGCNQTAVIKPLTKSYHGQSKSLTFTDISSKTLYNVEEEEDREPVRLNQPSSPSMVVHRRVATTPPLQAAAEETRLFLPEQSPKDLPLQPRSLMEQLQGVVNKLATGIPDFSAVLPAPGSGNGTRPPQQSPLLPLQAADFSGEPLSPPAEEAESEKLKLIQGYVYEKSTEDEEEEEPATSKLTLEDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPDMTYASVILRDYKQSSSTL", "length": 1152 }, "evidence": [ { "id": "A0A3Q1LK20", "url": "https://omabrowser.org/oma/group/A0A3Q1LK20/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P23385-1", "protein_name": "Metabotropic glutamate receptor 1", "gene_name": "Grm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRLLLIFFPMIFLEMSILPRMPDRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGMVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEFVQDEFTCRACDLGWWPNAELTGCEPIPVRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGGRQAPKGQHVWQRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDASTKTLYNVEEEDNTPSAHFSPPSSPSMVVHRRGPPVATTPPLPPHLTAEETPLFLADSVIPKGLPPPLPQQQPQQPPPQQPPQQPKSLMDQLQGVVTNFGSGIPDFHAVLAGPGTPGNSLRSLYPPPPPPQHLQMLPLHLSTFQEESISPPGEDIDDDSERFKLLQEFVYEREGNTEEDELEEEEDLPTASKLTPEDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL", "length": 1199 }, "evidence": [ { "id": "A0A3Q1LK20", "url": "https://omabrowser.org/oma/group/A0A3Q1LK20/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97772-1", "protein_name": "Metabotropic glutamate receptor 1", "gene_name": "Grm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRLLLIFFPMIFLEMSILPRMPDRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGYVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGMVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEFVQDEFTCRACDLGWWPNAELTGCEPITIRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGGRQAPKGQHVWQRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDASTKTLYNVEEEDNTPSTHFSPPSSPSMVVHRRGPPVATTPPLPPHLSAEETPLFLADSVIPKGLPPPLPQQQQQPPPQPPPQQPKSLMDQLQGVVTNFGSGIPDFHAVLAGPGTPGNGLRSLYPPPPPPQHLQMLPLQLSTFREEPISPPGEDDDDDSSERFKLLQEFVYEREGNTEEDDLEEEEDLPAASKLTPEDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL", "length": 1199 }, "evidence": [ { "id": "A0A3Q1LK20", "url": "https://omabrowser.org/oma/group/A0A3Q1LK20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13255-1", "protein_name": "Metabotropic glutamate receptor 1", "gene_name": "GRM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGLLLFFFPAIFLEVSLLPRSPGRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKAGAGNANSNGKSVSWSEPGGGQVPKGQHMWHRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDTSTKTLYNVEEEEDAQPIRFSPPGSPSMVVHRRVPSAATTPPLPSHLTAEETPLFLAEPALPKGLPPPLQQQQQPPPQQKSLMDQLQGVVSNFSTAIPDFHAVLAGPGGPGNGLRSLYPPPPPPQHLQMLPLQLSTFGEELVSPPADDDDDSERFKLLQEYVYEHEREGNTEEDELEEEEEDLQAASKLTPDDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVSYASVILRDYKQSSSTL", "length": 1194 }, "evidence": [ { "id": "A0A3Q1LK20", "url": "https://omabrowser.org/oma/group/A0A3Q1LK20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "adenylate cyclase inhibiting G protein-coupled glutamate receptor activity", "id": "GO:0001640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001640", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { "name": "G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential", "id": "GO:0099530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099530", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { "name": "neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration", "id": "GO:0099583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099583", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { "name": "glutamate receptor activity", "id": "GO:0008066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008066", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { "name": "G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration", "id": "GO:0098872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "phospholipase C-activating G protein-coupled glutamate receptor signaling pathway", "id": "GO:0007206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007206", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, glutamatergic", "id": "GO:0051966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051966", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { "name": "G protein-coupled glutamate receptor signaling pathway", "id": "GO:0007216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007216", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK20" } ], "pmid": "" }, { 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"A0A3Q1MWZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWZ3/entry", "sequence": { "sequence": "MNWILCLSLTLLLVVQTAWGALHTKEPLADTKYGTLRGKQIHVGKTPINVFLGVPFSKPPVGAHRFAAPEPPEPWEGIRDATTYAPVCLQESWGQVTSMYFNTHKRYKWLHFSEDCLYLNVHAPVRARGDPLQPVMIWFPGGAFLVGSASTYDGSELAAREKVVVVVLQHRLGILGFLSTGDSQARGNWALLDQIAALRWVQKNIEAFGGDPGCVTLFGQSSGAMCISGLMTSSLARGLFHRAISQSGTAVFQNFITPDPLKVAKKIAQLAGCNHNSTKILVDCLRTLSGAEVMRVSQKMRFFKLHSQEDPQKVVWFMSPVVDGVVFQDNPIVLLTQGQVAPVPYLLGVNNLEFNWLLPFIMKFPMSHLRKETIAKLLWSTSTLLNVTKEQLPLVMEEYLRDVDDHDQKMLQKHVMDLAADATFVYSTLQAAHYHHNAGFPVYLYEFEHYAPGTIVKPRTDGADHGDEIGFIFGSPFSKGHSSNKEKALSLQMMKYWANFARTGNPNGGKLPYWPRYNKDEKYLQLDLTTRVNFKPLLMGSPPRLPLPRHCKQFAVRHSSCSTLCLFTLD", "length": 570, "header": "tr|A0A3Q1MWZ3-1|EST4A_BOVIN Computationally mapped isoform of Carboxylesterase 4A OS=Bos taurus OX=9913 GN=CES4A PE=2 SV=1 CANONICAL=P0C6R3-1" }, "locus": { "chromosome": "18", "start_pos": 34689727, "end_pos": 34675934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077292.1", "url": "https://www.ensembl.org/id/ENSBTAT00000077292.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060152.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060152.1" } ] } }, { "isoform_ac": "A0AAF6ZJS1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZJS1/entry", "sequence": { "sequence": "MLFNHLILCHPLLLLLLVFTSALHTKEPLADTKYGTLRGKQIHVGKTPINVFLGVPFSKPPVGAHRFAAPEPPEPWEGIRDATTYAPVCLQESWGQVTSMYFNTHKRYKWLHFSEDCLYLNVHAPVRARGDPLQPVMIWFPGGAFLVGSASTYDGSELAAREKVVVVVLQHRLGILGFLSTGDSQARGNWALLDQIAALRWVQKNIEAFGGDPGCVTLFGQSSGAMCISGLMTSSLARGLFHRAISQSGTAVFQNFITPDPLKVAKKIAQLAGCNHNSTKILVDCLRTLSGAEVMRVSQKMRFFKLHSQEDPQKVVWFMSPVVDGVVFQDNPIVLLTQGQVAPVPYLLGVNNLEFNWLLPFIMKFPMSHLRKETIAKLLWSTSTLLNVTKEQLPLVMEEYLRDVDDHDQKMLQKHVMDLAADATFVYSTLQAAHYHHNAGFPVYLYEFEHYAPGTIVKPRTDGADHGDEIGFIFGSPFSKGHSSNKEKALSLQMMKYWANFARTGNPNGGKLPYWPRYNKDEKYLQLDLTTRVGVMLREEKMAFWKRLHQN", "length": 551, "header": "tr|A0AAF6ZJS1-1|EST4A_BOVIN Computationally mapped isoform of Carboxylesterase 4A OS=Bos taurus OX=9913 GN=CES4A PE=2 SV=1 CANONICAL=P0C6R3-1" }, "locus": { "chromosome": "18", "start_pos": 34689727, "end_pos": 34678276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052032.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052032.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050404.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050404.3" } ] } }, { "isoform_ac": "P0C6R3-1", "url": "https://www.uniprot.org/uniprotkb/P0C6R3/entry#P0C6R3-1", "sequence": { "sequence": "MNWILCLSLTLLLVVQTAWGALHTKEPLADTKYGTLRGKQIHVGKTPINVFLGVPFSKPPVGAHRFAAPEPPEPWEGIRDATTYAPVCLQESWGQVTSMYFNTHKRYKWLHFSEDCLYLNVHAPVRARGDPLQPVMIWFPGGAFLVGSASTYDGSELAAREKVVVVVLQHRLGILGFLSTGDSQARGNWALLDQIAALRWVQKNIEAFGGDPGCVTLFGQSSGAMCISGLMTSSLARGLFHRAISQSGTAVFQNFITPDPLKVAKKIAQLAGCNHNSTKILVDCLRTLSGAEVMRVSQKMRFFKLHSQEDPQKVVWFMSPVVDGVVFQDNPIVLLTQGQVAPVPYLLGVNNLEFNWLLPFIMKFPMSHLRKETIAKLLWSTSTLLNVTKEQLPLVMEEYLRDVDDHDQKMLQKHVMDLAADATFVYSTLQAAHYHHNAGFPVYLYEFEHYAPGTIVKPRTDGADHGDEIGFIFGSPFSKGHSSNKEKALSLQMMKYWANFARTGNPNGGKLPYWPRYNKDEKYLQLDLTTRVGVMLREEKMAFWKRLHQN", "length": 550, "header": "sp|P0C6R3-1|EST4A_BOVIN Isoform 1 of Carboxylesterase 4A OS=Bos taurus OX=9913 GN=CES4A PE=2 SV=1 CANONICAL=P0C6R3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 276, "start_aa": "Asn", "end_pos": 276, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn276", "evidence": [ { "id": "P0C6R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C6R3#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 386, "start_aa": "Asn", "end_pos": 386, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn386", "evidence": [ { "id": "P0C6R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C6R3#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:529706", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529706", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AE76-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAGWSMKWTLDLSLTLWLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQITSMYLNTRKQYEWLHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQGLFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNSTKIMVKCLKALPAEKVMLVSKKMTFFRANSHKDPKDIVWFLSPVVDGLVFPEDPVVLLTRGQVKPVPYLLGVNSAEFEWSLPFLMKLQLNQRIMNKNYITKLLWSCSILLNITEEQIPLVAREYLSDAISHHDWKMFRNHLIDLVGDATFVYATLQAARYHRDAGSPVYLYEFKHHAPGIIVKPRSDGADHGDELSYLFGSPFSKGSSRGEEKEFSLQMMKYWANFAHTGDPNDRELPYWPRFDKEEKYLQLDFDTRVGVKLREKQMTFWRRLRQPQKP", "length": 563 }, "evidence": [ { "id": "P0C6R3", "url": "https://omabrowser.org/oma/group/P0C6R3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XG92-1", "protein_name": "Carboxylesterase 4A", "gene_name": "CES4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRDAGLPVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFATGLSMGKEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLYQSQRPEKQRQF", "length": 561 }, "evidence": [ { "id": "P0C6R3", "url": "https://omabrowser.org/oma/group/P0C6R3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0W5-1", "protein_name": "Carboxylesterase 4A", "gene_name": "Ces4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAGWNMKWILGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVVDGVVFPEDPVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNITKEQVPVVAREYLNDAISNHDWKMFRNRLIDLIGDATFVYATLQAARYHRDAGSPVYLYEFKHHASSGIIIKPYNGADHGDELSYLFGSPFSKGSSAGEEKEFSLQMMKYWANFAHTGNPNGEKLPYWPRFDKDEKYLQLDFDTRVGVKLKEKKMAFWSQLRQSQKP", "length": 563 }, "evidence": [ { "id": "P0C6R3", "url": "https://omabrowser.org/oma/group/P0C6R3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P0C6R3", "url": "https://www.uniprot.org/uniprotkb/P0C6R3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "P0C6R3", "url": "https://www.uniprot.org/uniprotkb/P0C6R3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "P0C6R3", "url": "https://www.uniprot.org/uniprotkb/P0C6R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P0C6R3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 550, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P0C6R3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P0C6R3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 276, 386 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 386, "end_pos": 388 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 2 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_n_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 2 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_n_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G8JKZ9-1", "uniprot_ac": "G8JKZ9", "uniprot_id": "G8JKZ9_BOVIN", "mass": { "chemical_mass": 20279.0, "monoisotopic_mass": 20279.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "G8JKZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9", "locus": {} } ], "crossref": [ { "id": "G8JKZ9", "url": "https://alphafold.ebi.ac.uk/entry/G8JKZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016153", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000039879", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CPNTENS", "url": "https://omabrowser.org/oma/group/CPNTENS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10206:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10206:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MZC7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MZC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G8JKZ9-1", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METQRASLSLGRWSLWLLLLGLVLPSASAQALSYREAMLRAVDQLNERSSEDMSWGGDRGRPVNFRVKETVCPRSNLQPPEQCDFKENGLVKQCVGTLSLYRSDDPFGLNCNELQSVRRLHPQHQRFPRERPWPKPLSLPLPRPGPRPWPKPLLALWPRPMPSPRPFLLTSLIPRCP", "length": 177, "header": "tr|G8JKZ9-1|G8JKZ9_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=4 CANONICAL=G8JKZ9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MZC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZC7/entry", "sequence": { "sequence": "MGHSERLLVYPLYQVQTDYREAMLRAVDQLNERSSEAHLYRLLELDPFPTLTVDQVEDLGARKPVNFRVKETVCPRSNLQPPEQCDFKENGCVGTLSLYRSDDPFGLNCNEVSGPFCVMQMLTRWVVEHA", "length": 130, "header": "tr|A0A3Q1MZC7-1|G8JKZ9_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G8JKZ9-1" }, "locus": { "chromosome": "22", "start_pos": 51608606, "end_pos": 51607300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074203.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074203.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061535.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061535.2" } ] } }, { "isoform_ac": "G8JKZ9-1", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9/entry", "sequence": { "sequence": "METQRASLSLGRWSLWLLLLGLVLPSASAQALSYREAMLRAVDQLNERSSEDMSWGGDRGRPVNFRVKETVCPRSNLQPPEQCDFKENGLVKQCVGTLSLYRSDDPFGLNCNELQSVRRLHPQHQRFPRERPWPKPLSLPLPRPGPRPWPKPLLALWPRPMPSPRPFLLTSLIPRCP", "length": 177, "header": "tr|G8JKZ9-1|G8JKZ9_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=4 CANONICAL=G8JKZ9-1" }, "locus": { "chromosome": "22", "start_pos": 51608515, "end_pos": 51606533, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044798.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044798.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042257.5", "url": "https://www.ensembl.org/id/ENSBTAP00000042257.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "G8JKZ9", "url": "https://www.uniprot.org/uniprotkb/G8JKZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G8JKZ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 177, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G8JKZ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G8JKZ9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LN60-1", "uniprot_ac": "A0A3Q1LN60", "uniprot_id": "A0A3Q1LN60_BOVIN", "mass": { "chemical_mass": 57597.0, "monoisotopic_mass": 57597.0 }, "refseq": {}, "gene_names": [ { "name": "ACVR2B", "type": "recommended", "evidence": [ { "id": "A0A3Q1LN60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LN60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.30", "type": "synonym", "evidence": [ { "id": "A0A3Q1LN60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACVR2B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60", "locus": { "chromosome": "22", "start_pos": 11855763, "end_pos": 11825975, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018105", "url": "https://www.ensembl.org/id/ENSBTAG00000018105" } ] } } ], "crossref": [ { "id": "A0A3Q1LN60", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LN60", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018105", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018105", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14140", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14140", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23632", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23632", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WLELCRI", "url": "https://omabrowser.org/oma/group/WLELCRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LN60", "url": "https://www.orthodb.org/?gene=A0A3Q1LN60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N4Z4", "url": "https://www.orthodb.org/?gene=A0A3Q1N4Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MH84", "url": "https://www.orthodb.org/?gene=F1MH84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23255:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23255:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "18673", "url": "https://www.rhea-db.org/rhea/18673", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44880", "url": "https://www.rhea-db.org/rhea/44880", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN60-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N4Z4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N4Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T664", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T664", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T664-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T664-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MH84", "url": "https://www.uniprot.org/uniprotkb/F1MH84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MH84-1", "url": "https://www.uniprot.org/uniprotkb/F1MH84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI", "length": 512, "header": "tr|A0A3Q1LN60-1|A0A3Q1LN60_BOVIN Isoform 1 of Serine/threonine-protein kinase receptor OS=Bos taurus OX=9913 GN=ACVR2B PE=3 SV=2 CANONICAL=A0A3Q1LN60-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LN60-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60/entry", "sequence": { "sequence": "MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI", "length": 512, "header": "tr|A0A3Q1LN60-1|A0A3Q1LN60_BOVIN Isoform 1 of Serine/threonine-protein kinase receptor OS=Bos taurus OX=9913 GN=ACVR2B PE=3 SV=2 CANONICAL=A0A3Q1LN60-1" }, "locus": { "chromosome": "22", "start_pos": 11855622, "end_pos": 11826133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084197.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084197.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058381.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058381.2" } ] } }, { "isoform_ac": "A0A3Q1N4Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4Z4/entry", "sequence": { "sequence": "MPSPASPAGGPAAEHPGEPPPPWAWGSEAVDTGARAPPLPKGSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI", "length": 536, "header": "tr|A0A3Q1N4Z4-1|A0A3Q1LN60_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase receptor OS=Bos taurus OX=9913 GN=ACVR2B PE=3 SV=2 CANONICAL=A0A3Q1LN60-1" }, "locus": { "chromosome": "22", "start_pos": 11855622, "end_pos": 11831248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068804.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068804.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065004.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065004.2" } ] } }, { "isoform_ac": "A0AAA9T664-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T664/entry", "sequence": { "sequence": "MGKVAKRGGQILYGGSGIVGAAAAGGRIARPSQPLRCSGAKRAASHSQRSLLHSTPPRLRGVPREARRWRQLPPAPAFPAAPRYARCGHSEELLCFGAPGRRGSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI", "length": 597, "header": "tr|A0AAA9T664-1|A0A3Q1LN60_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase receptor OS=Bos taurus OX=9913 GN=ACVR2B PE=3 SV=1 CANONICAL=A0A3Q1LN60-1" }, "locus": { "chromosome": "22", "start_pos": 11855622, "end_pos": 11826491, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094946.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094946.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091269.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091269.1" } ] } }, { "isoform_ac": "F1MH84-1", "url": "https://www.uniprot.org/uniprotkb/F1MH84/entry", "sequence": { "sequence": "MLCAAVGGRRVGLCPAPVCSPAWGSGPQVTRGPPLDLLPWMQWVLCALWIGGFAEYAAANAAAGRRGEGEVWASLAPAWALPQCFHPIPSAPPLASRAAETRQSHGQEAALLVSPKWSPSFARKPPGTKGVVKTQILPPLQLAGSGLGPGIGMSSITLPPHSSTHGDSDMPAVAGRHPELRVLAEPLPVHWLPVCARPSSSPGAWGGSAAAASWAQVRGAGRPRHGSASTTTPTGSWSAPTRAAWSAARASGTSGCTATPPGATARAPSSSSRKAAGWTTSTATTGAGTPEAGSLESTRAVAGSQPSRVLRSPVMLEGLSPPWICVPLLGSPTPTVPHRISVCGEGFGWAALGVCSSAELWMGNCASRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI", "length": 793, "header": "tr|F1MH84-1|F1MH84_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase receptor OS=Bos taurus OX=9913 GN=ACVR2B PE=3 SV=3 CANONICAL=A0A3Q1LN60-1" }, "locus": { "chromosome": "22", "start_pos": 11855622, "end_pos": 11848521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024095.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024095.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024095.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024095.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480RUT4-1", "protein_name": "Serine/threonine-protein kinase receptor", "gene_name": "ACVR2B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTAPWAALALLWGSLCVGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI", "length": 512 }, "evidence": [ { "id": "A0A3Q1LN60", "url": "https://omabrowser.org/oma/group/A0A3Q1LN60/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P27040-1", "protein_name": "Activin receptor type-2B", "gene_name": "Acvr2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEPGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEVRQCQRWAGRRDGCADSFKPLPFQDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLLPKESSI", "length": 536 }, "evidence": [ { "id": "A0A3Q1LN60", "url": "https://omabrowser.org/oma/group/A0A3Q1LN60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38445-1", "protein_name": "Activin receptor type-2B", "gene_name": "Acvr2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEPGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGCSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNSSTSDCLVSLVTSVTNVDLLPKESSI", "length": 513 }, "evidence": [ { "id": "A0A3Q1LN60", "url": "https://omabrowser.org/oma/group/A0A3Q1LN60/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13705-1", "protein_name": "Activin receptor type-2B", "gene_name": "ACVR2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAPWVALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI", "length": 512 }, "evidence": [ { "id": "A0A3Q1LN60", "url": "https://omabrowser.org/oma/group/A0A3Q1LN60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q24468-1", "protein_name": "Receptor protein serine/threonine kinase put", "gene_name": "put", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKYDLLYLTAQLTLVCCLIGIHGSILPGSHGIIECEHFDEKMCNTTQQCETRIEHCKMEADKFPSCYVLWSVNETTGILRIKMKGCFTDMHECNQTECVTSAEPRQGNIHFCCCKGSRCNSNQKYIKSTTEATTQVPKEKTQDGSNLIYIYIGTSVFSVLMVIVGMGLLLYRRRKQAHFNEIPTHEAEITNSSPLLSNRPIQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKHMDKPEYWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEVLEGAINFNRDAFLRIDVYACGLVLWEMVSRCDFAGPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPGLNVFCDTMEECWDHDAEARLSSSCVMERFAQLNKYPSTQLLIKNHTNIDDAKESTNCL", "length": 516 }, "evidence": [ { "id": "A0A3Q1LN60", "url": "https://omabrowser.org/oma/group/A0A3Q1LN60/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q90670-1", "protein_name": "Activin receptor type-2B", "gene_name": "ACVR2B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSASWLTLAVLCATLGAGPGHGEAETRECIYYNANWELEKTNQSGVERCEGEKDKRLHCYASWRNNSGSIELVKKGCWLDDFNCYDRQECVATEENPQVFFCCCEGNYCNEKFTHLPEVTGPEVIYEPPPPTPSLLNILVYSLLPIAVLSVAILLAFWMYRHRKPPYGHVDINEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDYVAVKIFPIQDKQSWQSEREIFNTPGMKHENLLQFIAAEKRGTNLETELWLITAFHDKGSLTDYLKGNIISWNELCHVAETMARGLSYLHEDVPWCKGEGHKPAIAHRDFKSKNVLLKNDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCRAVDGPVDEYMLPFEEEIGQHPSLEDLQEVVVHKKMRPVFKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERIAQIRKSVNGTTSDCLVSIVTSVTNVDLPPKESSI", "length": 512 }, "evidence": [ { "id": "A0A3Q1LN60", "url": "https://omabrowser.org/oma/group/A0A3Q1LN60/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ], "pmid": "" }, { "name": "transmembrane receptor protein serine/threonine kinase activity", "id": "GO:0004675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004675", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN60", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18673", "name": "", "equation": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MZV8-1", "O46680-1", "F6RIX5-1", "A0A3Q1LN60-1", "Q28041-1", "Q28043-1", "Q95126-1", "E1BHR7-1", "F1MIW7-1", "F1MMW7-1", "A0AAA9RZ76-1", "A0A3Q1LP90-1" ], "evidence": [ { "id": "18673", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18673" } ] }, { "id": "44880", "name": "", "equation": "L-threonyl-[receptor-protein] + ATP = O-phospho-L-threonyl-[receptor-protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLS3-1", "A0A3Q1LN60-1", "O46680-1", "F6RIX5-1", "E1BHR7-1", "G3MZV8-1", "Q28041-1", "Q28043-1", "Q95126-1", "F1MIW7-1", "F1MMW7-1", "A0AAA9RZ76-1", "A0A3Q1LP90-1" ], "evidence": [ { "id": "44880", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44880" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LN60", "gene_name": "ACVR2B", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "A0A3Q1LN60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" } ] } ] }, { "uniprot_ac": "A0A3Q1LP90", "gene_name": "BMPR2", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP90" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "A0A3Q1LP90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP90" } ] } ] }, { "uniprot_ac": "A0AAA9RZ76", "gene_name": "ACVR1B", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RZ76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ76" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "A0AAA9RZ76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ76" } ] } ] }, { "uniprot_ac": "A0AAF6DLS3", "gene_name": "BMPR1B", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLS3" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "A0AAF6DLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLS3" } ] } ] }, { "uniprot_ac": "E1BHR7", "gene_name": "AMHR2", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "E1BHR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHR7" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "E1BHR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHR7" } ] } ] }, { "uniprot_ac": "F1MIW7", "gene_name": "ACVRL1", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "F1MIW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIW7" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "F1MIW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIW7" } ] } ] }, { "uniprot_ac": "F1MMW7", "gene_name": "ACVR1C", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "F1MMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMW7" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "F1MMW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMW7" } ] } ] }, { "uniprot_ac": "F6RIX5", "gene_name": "ACVR1", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "F6RIX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RIX5" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "F6RIX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RIX5" } ] } ] }, { "uniprot_ac": "G3MZV8", "gene_name": "TGFBR2", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "G3MZV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZV8" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "G3MZV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZV8" } ] } ] }, { "uniprot_ac": "O46680", "gene_name": "TGFBR1", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "O46680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46680" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "O46680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46680" } ] } ] }, { "uniprot_ac": "Q28041", "gene_name": "ACVR1", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "Q28041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28041" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "Q28041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28041" } ] } ] }, { "uniprot_ac": "Q28043", "gene_name": "ACVR2A", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "Q28043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28043" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "Q28043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28043" } ] } ] }, { "uniprot_ac": "Q95126", "gene_name": "ACVR2B", "activity": [ { "ec_number": "2.7.11.30", "activity": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "Q95126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95126" } ] }, { "ec_number": "2.7.11.30", "activity": "", "evidence": [ { "id": "Q95126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95126" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LN60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN60" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 190, "end_pos": 480, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.30", "ec_name": "L-seryl-[receptor-protein] + ATP = O-phospho-L-seryl-[receptor-protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.30", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.30" }, { "id": "2.7.11.30", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.30" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 131 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LML0-1", "uniprot_ac": "A0A3Q1LML0", "uniprot_id": "A0A3Q1LML0_BOVIN", "mass": { "chemical_mass": 122788.0, "monoisotopic_mass": 122788.0 }, "refseq": {}, "gene_names": [ { "name": "LOC538674", "type": "recommended", "evidence": [ { "id": "A0A3Q1LML0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" } ] } ], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A3Q1LML0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Potential calcium-dependent cell-adhesion protein.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T1H2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1H2#function" }, { "database": "UniProtKB", "id": "ARBA00037723", "url": "https://www.uniprot.org/uniprotkb/ARBA00037723#function" }, { "database": "UniProtKB", "id": "A0AAA9S3D3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3D3#function" }, { "database": "UniProtKB", "id": "A0AAA9RTR3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTR3#function" }, { "database": "UniProtKB", "id": "A0AAA9T2M9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2M9#function" }, { "database": "UniProtKB", "id": "A0A3Q1N768", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N768#function" }, { "database": "UniProtKB", "id": "A0AAA9RVL0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVL0#function" }, { "database": "UniProtKB", "id": "A0AAA9SB71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB71#function" }, { "database": "UniProtKB", "id": "A0AAA9TZ17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ17#function" }, { "database": "UniProtKB", "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0#function" }, { "database": "UniProtKB", "id": "F1N446", "url": "https://www.uniprot.org/uniprotkb/F1N446#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC538674", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0", "locus": {} } ], "crossref": [ { "id": "A0A3Q1LML0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LML0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001911", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001911", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538674", "url": "https://www.ncbi.nlm.nih.gov/gene/538674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538674", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538674", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHTRQVM", "url": "https://omabrowser.org/oma/group/IHTRQVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LML0", "url": "https://www.orthodb.org/?gene=A0A3Q1LML0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N446", "url": "https://www.orthodb.org/?gene=F1N446", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LML0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N768", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N768", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N768-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N768-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTR3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVL0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3D3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3D3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB71-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1H2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1H2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2M9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZ17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZ17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N446", "url": "https://www.uniprot.org/uniprotkb/F1N446", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N446-1", "url": "https://www.uniprot.org/uniprotkb/F1N446-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQQKSKGKRTIKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESK", "length": 1112, "header": "tr|A0A3Q1LML0-1|A0A3Q1LML0_BOVIN Isoform 1 of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=2 CANONICAL=A0A3Q1LML0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LML0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQQKSKGKRTIKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESK", "length": 1112, "header": "tr|A0A3Q1LML0-1|A0A3Q1LML0_BOVIN Isoform 1 of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=2 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40550645, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076402.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076402.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057953.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057953.2" } ] } }, { "isoform_ac": "A0A3Q1N768-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N768/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQQKSKGKRTIKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESNYCQRASLVAQVYWSFSFNNSPSNEH", "length": 1137, "header": "tr|A0A3Q1N768-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=2 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40722945, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073687.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073687.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066456.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066456.2" } ] } }, { "isoform_ac": "A0AAA9RTR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTR3/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESTAEITIQPTVEEASDNCTQECLILGHSDACWMPASLTHSSPSQAQASALCHSPPPTQTTLHRRNPLVTQTVALCHSPPMTQAIALCHSSPPAQTSALHHSPPLAQALHHSPLPAQASALYYSPPLAQAASINCSPPLPQPAALHCSPVQPPVGLQQGWGQGVGPEGLLSLDQGAQGSTRSHFYAMSERLHPSDDSIKVIPLTTFTPGQQARPSRGDSPIMEEHPL", "length": 1326, "header": "tr|A0AAA9RTR3-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=1 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40835268, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129200.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129200.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076436.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076436.1" } ] } }, { "isoform_ac": "A0AAA9RVL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVL0/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLT", "length": 1009, "header": "tr|A0AAA9RVL0-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=1 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40098350, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113126.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113126.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076368.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076368.1" } ] } }, { "isoform_ac": "A0AAA9S3D3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3D3/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLTDSRTSTIEIYSEI", "length": 1022, "header": "tr|A0AAA9S3D3-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=1 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 39953541, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112950.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112950.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079612.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079612.1" } ] } }, { "isoform_ac": "A0AAA9SB71-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB71/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESTFIPGLKKAAEITIQPTVEEASDNCTQECLILGHSDACWMPASLTHSSPSQAQASALCHSPPPTQTTLHRRNPLVTQTVALCHSPPMTQAIALCHSSPPAQTSALHHSPPLAQALHHSPLPAQASALYYSPPLAQAASINCSPPLPQPAALHCSPVQPPVGLQQGWGQGVGPEGLLSLDQGAQGSTRSHFYAMSERLHPSDDSIKVIPLTTFTPGQQARPSRGDSPIMEEHPL", "length": 1307, "header": "tr|A0AAA9SB71-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=1 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40835268, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130825.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130825.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079435.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079435.1" } ] } }, { "isoform_ac": "A0AAA9T1H2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1H2/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQQKSKGKRTIKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESTFIPGLKKAAEITIQPTVEEASDNCTQECLILGHSDACWMPASLTHSSPSQAQASALCHSPPPTQTTLHRRNPLVTQTVALCHSPPMTQAIALCHSSPPAQTSALHHSPPLAQALHHSPLPAQASALYYSPPLAQAASINCSPPLPQPAALHCSPVQPPVGLQQGWGQGVGPEGLLSLDQGAQGSTRSHFYAMSERLHPSDDSIKVIPLTTFTPGQQARPSRGDSPIMEEHPL", "length": 1344, "header": "tr|A0AAA9T1H2-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=1 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40835268, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122868.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122868.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091559.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091559.1" } ] } }, { "isoform_ac": "A0AAA9T2M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2M9/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLTWGISSRMLQQSTATAPYIGHGLSPLGCRS", "length": 1038, "header": "tr|A0AAA9T2M9-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=1 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40011135, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101803.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101803.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090894.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090894.1" } ] } }, { "isoform_ac": "A0AAA9TZ17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ17/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQQKSKGKRTIKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESTAEITIQPTVEEASDNCTQECLILGHSDACWMPASLTHSSPSQAQASALCHSPPPTQTTLHRRNPLVTQTVALCHSPPMTQAIALCHSSPPAQTSALHHSPPLAQALHHSPLPAQASALYYSPPLAQAASINCSPPLPQPAALHCSPVQPPVGLQQGWGQGVGPEGLLSLDQGAQGSTRSHFYAMSERLHPSDDSIKVIPLTTFTPGQQARPSRGDSPIMEEHPL", "length": 1336, "header": "tr|A0AAA9TZ17-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=1 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40835268, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101849.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101849.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101957.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101957.1" } ] } }, { "isoform_ac": "F1N446-1", "url": "https://www.uniprot.org/uniprotkb/F1N446/entry", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIIVDTHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYQLIKGQNIFGLDIIETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPVFKEDEIEVSIPENAPVGSSVTQLHATDADIGENARIHFYFSSLVSSVAKRLFHLNSTTGLITVKEPLDREESPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPLIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLASDAGKPPLNQSSMLLIKLKDENDNAPVFTQPFISLSVPENNSPGTQLTKISATDADTGRNAEIHYLLGIDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPSLITNATVLVTILDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVTLSILDANDDFTIDPQSGVIQPNISFDREKQESYTFNVKAEDGGRVSHSSTAKVTINVVDVNDNKPVFVVPPSNYSFELVSPSANPGTVVFTVVAIDNDTGMNAELRYSILGGNTKGLFMIDQTTGNITLKEKCVLADLGLHKLIVKAKDLGQPDSLFSVINVNLFVNESMTNATLIYELVRKNIEIPVTQNVETTHTSSPSSDYVKIMVAIVAGTITVILVIFITAVVRCRQSPHLKAAQKNKQNSEWVTPNPENRQMMMMKKKKKHTPKNLLLNFVTIEEAKADDADNDRNTVTLDLPVELEEQTMVKYNWGTTPTTFKPDSPDLAQHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSISECSYPVTNIKTPVSVHTRLPMKEVVRSHTPMKGTTTVEIWTHPQPQSQRRVTFHLPEGSQESSSDGGLGDHDAGSLSSTSHALPLGYPQEEYFDHAANNNRTEGDGNSDPESTKDGDALNSLQNQDRDVTVVQIMNSLLPNSDLN", "length": 1134, "header": "tr|F1N446-1|A0A3Q1LML0_BOVIN Computationally mapped isoform of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC538674 PE=4 SV=4 CANONICAL=A0A3Q1LML0-1" }, "locus": { "chromosome": "X", "start_pos": 40626987, "end_pos": 39912853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002483.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002483.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002483.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002483.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538674", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QW78-1", "protein_name": "Protocadherin 11 X-linked", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLLSGTYIFAVLLACIVFQSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAAIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESPNHKLLVLASDGGLTPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGRVSCFTDHEVPFRLRPVFSNQFLLETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQPDSLFNVVNVNLFVNESVTNATLIYELVRKNIETPVTQNIETTDASSPSSDYVKIVVAIVAGTITVILVIFITAVVRCQQSPHLKAAQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHAPKNLLLNFVTIEEAKADDADNNRSSITLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPTFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEAIRSHTPMKETTTVEIWTHPQPQRKSEGKRAGKSQRRVTFHLPEGSQESSSDGGLGDHDTGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESAFIPGLKKGAEITVEPTVEEASDNCTQECLILGHSDACWMPASLTHSSPQQTQASGLCHSPPMTQTTLRHRSPPVTQTVALCHSPPVTQTITLCHSPPLAHTSALHHSPPLAKATPLRHSPPPAQASALHYSPTLAQAVAIQHSPPLPQAAALHRSPAQPQMGLQQGWGQGASPDGLNSLNQGLQGSARSQFYTMSERLHPSDDSIKVIPLTTFTPGQQARPSRGESPIMEEHPL", "length": 1350 }, "evidence": [ { "id": "A0A3Q1LML0", "url": "https://omabrowser.org/oma/group/A0A3Q1LML0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0L546-1", "protein_name": "Protocadherin 11 X-linked", "gene_name": "Pcdh11x", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQTPGGSDPCRRASENCAHSRAPRVGGIGLPGMLPFLPALGPSECGNVYRGLTNSTFGIETGMDLLSGTYIFAVLLACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQNVFGLDVVETPEGEKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNRPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNNAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPAKAMVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVTDKDSEHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGRNAEINYLLGFDAPPEFNLDRRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPENLPKHGTVGLITVTDPDYGENSAVTLSVLDVNDQFTIDPQSGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSTAKVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTDPGTVIFKVLAIDNDTGMNAELRYSIVGGNTKGLFMIEQISGNITLKEKCMVSDIGLHRVIVKAKDLGQPDSLFNVVNVNLFVNESVPNTTLIYEMVRKSIDSPANQNSETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQSPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVSIEEAKPDDADNERNSVTLDLPIELEDQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKTPVSVHTRPPMKEVVRSHTPMKEATTVEIWTHPHPQRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHDPGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESTAEITVQPTVEEASDTCTQECLILGHSDSCWMPASLTNPTPSQIKTSAICHSPPRTHSSVRRCSPPVTQTVAICHSPPVTQAIALCHSPPPVQATVLRHSSPPAQASAVCYSPTLVQAVVIHRSPPLPQAATLRHTQAQPPMGLQQGWVQGAGADGTHPIDQGVQGSTRAQFYTMAERLHPDDDSIKVIPLTTFTSGKQARASRGDSPIMEEHPL", "length": 1393 }, "evidence": [ { "id": "A0A3Q1LML0", "url": "https://omabrowser.org/oma/group/A0A3Q1LML0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6ZNL5-1", "protein_name": "Protocadherin 11 X-linked", "gene_name": "Pcdh11x", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFQSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAVTLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESVPNATLIYELVRRSIDAPANQNTETTSASSPTTDYVKIMVAIVAGTITVVLVIFITAVVRCRQPPHLKASQKNKQNSEWVTPNPENRQMIMMKKKKKKKKKHPPKNLLLNFVTIEEAKPDDGENERNSVTLDLPIELEEQTMGKYNWGTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVGCDSISKCSSSSSDPYSVSECSYPVTTFKAPVSVHIRPTMKEVVRSHTPMKEATTVEIWTHPHPQRRSDGKKAGKSQRRVTFHLPEGSQESISDGGLGDHDAGSLPSTSHALPLGYPQEEYFDHAAPNNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDTCTQECLILGHSDSCWMPATLTNPSPSQIKTSAICHSPPRPRLSVRRYSPPVTQTVTICHSPPVTQAIALCHSPPPVQVTVPRHSPPPAQASAVSYSPTLVQAVVIHHSPPLPQAATHHRTQAQPPMGLQQGWVQGAGADGLYPIDQGVQGSTRAQFYTMAERFHPDDDSIKVIPLTTFTSGQQARSSRGDSPIIEEHPL", "length": 1338 }, "evidence": [ { "id": "A0A3Q1LML0", "url": "https://omabrowser.org/oma/group/A0A3Q1LML0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZA7-1", "protein_name": "Protocadherin-11 X-linked", "gene_name": "PCDH11X", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPRQQARPSRGDSPIMEEHPL", "length": 1347 }, "evidence": [ { "id": "A0A3Q1LML0", "url": "https://omabrowser.org/oma/group/A0A3Q1LML0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LML0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1099, "end_pos": 1101, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LML0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML0" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 139, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1099, "end_pos": 1101 }, { "start_pos": 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"common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM134", "url": "https://www.uniprot.org/uniprotkb/Q05B54", "locus": { "chromosome": "29", "start_pos": 45352400, "end_pos": 45357297, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004786", "url": "https://www.ensembl.org/id/ENSBTAG00000004786" } ] } } ], "crossref": [ { "id": "Q05B54", "url": "https://alphafold.ebi.ac.uk/entry/Q05B54", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004786", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004786", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510129", "url": "https://www.ncbi.nlm.nih.gov/gene/510129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039714", "url": 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"Protein Classification", "Other" ] }, { "id": "NP_001073723", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DI15", "url": "https://www.uniprot.org/uniprotkb/A0A452DI15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DI15-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJ18", "url": "https://www.uniprot.org/uniprotkb/A0A452DJ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJ18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSF4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSF4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"MSASRPQFSIDDAFELSLEDTGPGLEPSGVARFGPLHFERRARFEVADEDKQSRLRYQNLENDEDGAQASPEPDGGVSSRDSGQTSIRSSQWSFSSISSSTQRSYNACCSWTQHPLIQKNHRVVLASFLLLLLGLGVSSAIFFVPGFLLLVPGVYHVIFIYCAVKGHRGLPVLLPALLREVSNWR", "length": 185, "header": "tr|A0AAA9SSF4-1|TM134_BOVIN Computationally mapped isoform of Transmembrane protein 134 OS=Bos taurus OX=9913 GN=TMEM134 PE=2 SV=1 CANONICAL=Q05B54-1" }, "locus": { "chromosome": "29", "start_pos": 45357252, "end_pos": 45352722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110455.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110455.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088262.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088262.1" } ] } }, { "isoform_ac": "A0AAA9TBZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBZ1/entry", "sequence": { "sequence": "MSASRPQFSIDDAFELSLEDTGPGLEPSGVARFGPLHFERRARFEVADEDKQSRLRYQNLENDEDGAQASPEPDGGVSSRDSGQTSIRSSQWSFSSISSSTQRSYNACCRPKPRGRSRVEVPTLPPASASCGASLTLAAPFVCSADPDRRGTGGGPLARCLQRHLLRAGLPVAGPRSLPRDLHLLRRQGSPGASSSSTCPTSRSEQLEVDGGIQRQRREAPVCAASSHP", "length": 229, "header": "tr|A0AAA9TBZ1-1|TM134_BOVIN Computationally mapped isoform of Transmembrane protein 134 OS=Bos taurus OX=9913 GN=TMEM134 PE=2 SV=1 CANONICAL=Q05B54-1" }, "locus": { "chromosome": "29", "start_pos": 45357252, "end_pos": 45352660, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103316.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103316.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095560.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095560.1" } ] } }, { "isoform_ac": "Q05B54-1", "url": "https://www.uniprot.org/uniprotkb/Q05B54/entry#Q05B54-1", "sequence": { "sequence": "MSASRPQFSIDDAFELSLEDTGPGLEPSGVARFGPLHFERRARFEVADEDKQSRLRYQNLENDEDGAQASPEPDGGVSSRDSGQTSIRSSQWSFSSISSSTQRSYNACCSWTQHPLIQKNHRVVLASFLLLLLGLVLILTGVGLEVAPSPGVSSAIFFVPGFLLLVPGVYHVIFIYCAVKGHRGFQFFYLPYFEK", "length": 195, "header": "sp|Q05B54-1|TM134_BOVIN Isoform 1 of Transmembrane protein 134 OS=Bos taurus OX=9913 GN=TMEM134 PE=2 SV=2 CANONICAL=Q05B54-1" }, "locus": {} }, { "isoform_ac": "Q05B54-2", "url": "https://www.uniprot.org/uniprotkb/Q05B54/entry#Q05B54-2", "sequence": { "sequence": "MSASRPQFSIDDAFELSLEDTGPGLEPSGVARFGPLHFERRARFEVADEDKQSRLRYQNLENDEDGAQASPEPDGGVSSRDSGQTSIRSSQWSFSSISSSTQRSYNACCSWTQHPLIQKNHRVVLASFLLLLLGLGVSSAIFFVPGFLLLVPGVYHVIFIYCAVKGHRGFQFFYLPYFEK", "length": 180, "header": "sp|Q05B54-2|TM134_BOVIN Isoform 2 of Transmembrane protein 134 OS=Bos taurus OX=9913 GN=TMEM134 PE=2 SV=2 CANONICAL=Q05B54-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 93, "end_pos": 93, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", 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"gene_name": "Tmem134", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAARPQFSIDDAFELTLEDAGPEPESSGVARFGPLHFERRARFEVADEDKQSRLRYQNLENDEDGAQASPEPDGGVSTRDSGHMSVRSSQWSFSTISSSTQRSYNACCSWTQHPLIQKNRRVVLASFLLLLLGLVLILVGVGLEVAPSPGVSSAIFFVPGILLLVPGVYHVIFIYCAVKGRRGFQFFYLPYFEK", "length": 195 }, "evidence": [ { "id": "Q05B54", "url": "https://omabrowser.org/oma/group/Q05B54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6X4-1", "protein_name": "Transmembrane protein 134", "gene_name": "TMEM134", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAARPQFSIDDAFELSLEDGGPGPESSGVARFGPLHFERRARFEVADEDKQSRLRYQNLENDEDGAQASPEPDGGVGTRDSSRTSIRSSQWSFSTISSSTQRSYNTCCSWTQHPLIQKNRRVVLASFLLLLLGLVLILVGVGLEATPSPGVSSAIFFVPGFLLLVPGVYHVIFIYCAVKGHRGFQFFYLPYFEK", "length": 195 }, "evidence": [ { "id": "Q05B54", "url": "https://omabrowser.org/oma/group/Q05B54/", "database": "OMA" } ], "glygen_name": "Human", 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZX4" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "Q3SZX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZX4" } ] } ] }, { "uniprot_ac": "Q95323", "gene_name": "CA4", "activity": [ { "ec_number": "4.2.1.1", "activity": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "Q95323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95323" } ] }, { "ec_number": "4.2.1.1", "activity": "", "evidence": [ { "id": "Q95323", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95323" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A0A0MP99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MP99" }, { "id": "PS51144", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51144" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-carbonic anhydrase", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 261, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.1", "ec_name": "hydrogencarbonate + H(+) = CO2 + H2O.", "evidence": [ { "id": "4.2.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.1" }, { "id": "4.2.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.1" } ] }, { "ec_number": "4.2.1.69", "ec_name": "urea = cyanamide + H2O.", "evidence": [ { "id": "4.2.1.69", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.69" }, { "id": "4.2.1.69", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.69" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5K2-1", "uniprot_ac": "G5E5K2", "uniprot_id": "G5E5K2_BOVIN", "mass": { "chemical_mass": 97844.0, "monoisotopic_mass": 97844.0 }, "refseq": { "ac": "XP_005214293", "name": "serine/threonine-protein kinase greatwall isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214293" }, "gene_names": [ { "name": "MASTL", "type": "recommended", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "name": "GWL", "type": "synonym", "evidence": [ { "id": "XP_005214293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214293" } ] }, { "name": "GW", "type": "synonym", "evidence": [ { "id": "XP_005214293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214293" } ] }, { "name": "MAST-L", "type": "synonym", "evidence": [ { "id": "XP_005214293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214293" } ] }, { "name": "MASTL", "type": "synonym", "evidence": [ { "id": "XP_005214293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214293" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase greatwall", "type": "recommended", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2/entry#names_and_taxonomy" } ] }, { "name": "Microtubule-associated serine/threonine-protein kinase-like", "type": "synonym", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase greatwall isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005214293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214293" } ] } ], "function": [ { "annotation": "Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TM22", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM22#function" }, { "database": "UniProtKB", "id": "ARBA00058869", "url": "https://www.uniprot.org/uniprotkb/ARBA00058869#function" }, { "database": "UniProtKB", "id": "A0AAA9TRD8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRD8#function" }, { "database": "UniProtKB", "id": "A0AAA9S9S4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S4#function" }, { "database": "UniProtKB", "id": "A0AAA9SJ54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ54#function" }, { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MASTL", "url": "https://www.uniprot.org/uniprotkb/G5E5K2", "locus": { "chromosome": "13", "start_pos": 17794080, "end_pos": 17750045, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017271", "url": "https://www.ensembl.org/id/ENSBTAG00000017271" } ] } } ], "crossref": [ { "id": "G5E5K2", "url": "https://alphafold.ebi.ac.uk/entry/G5E5K2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017271", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017271", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05610", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05610", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540206", "url": "https://www.ncbi.nlm.nih.gov/gene/540206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G5E5K2", "url": "https://www.orthodb.org/?gene=G5E5K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24356:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24356:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2465910", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2465910", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005214293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9S9S4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9S4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SII0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SII0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SII0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SII0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM22", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM22-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRD8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRD8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5K2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPTMGGEMESGGGAATGECVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGNRLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFHTPVAEGNHDTANVLSTQVSETSPLSQGLTCPMSVDQKDTTPYSSKLLKSCPEMVASHPRMPVKCLTSHLLQSRKRLATSSTSSPSHTFISSMESECHSSPRWEKDCQESDDAAGSTMMSWNTVEKPLCTKSVDAMETKSFNERDLELALSPIHNSSVVPATGNSYVNLAKKCSSGEVSWEARELDVNNINMTADTSQYCFHESNQRAVDSGGMTEEHLGKRSCKRIFELVDSSPRQGIIPNKKSCFEYECSNEMRDCYATQRTGFAFEVQDLKLLVYRDQQNDCVNKENVGSSFTDKHQTPEKSPVPMIEKNLMCELDDDCDKNSKKDYLSSSFLCSDGDRTPKSIHMDSDSSFPGISIMESPLGGQSLDPDKNIKESSLEESNIEDLLPVSPSCQESTLPKGVECPTIQDSNQKMLAPSSEVLKPLTSKRNAVAFRSFNSHINASNSSEPSKMSITSLDMMDVSCAYSGSYPTAITPTQRERSDMPYQQTPNQVKSETPYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLARAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVDILLTIDDTKRAGMKELKHHPLFSGVDWENLQHQKMPFIPQPDDETDTSYFEARNNAQHLTVSGFSL", "length": 881, "header": "tr|G5E5K2-1|G5E5K2_BOVIN Isoform 1 of Serine/threonine-protein kinase greatwall OS=Bos taurus OX=9913 GN=MASTL PE=3 SV=2 CANONICAL=G5E5K2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S9S4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S4/entry", "sequence": { "sequence": "MEPTMGGEMESGGGAATGECVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGNRLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFHTPVAEGNHDTANVLSTQVSETSPLSQGLTCPMSVDQKDTTPYSSKLLKSCPEMVASHPRMPVKCLTSHLLQSRKRLATSSTSSPSHTFISSMESECHSSPRWEKDCQESDDAAGSTMMSWNTVEKPLCTKSVDAMETKSFNERDLELALSPIHNSSVVPATGNSYVNLAKKCSSGEVSWEARELDVNNINMTADTSQYCFHESNQRAVDSGGMTEEHLGKRSCKRIFELVDSSPRQGIIPNKKSCFEYECSNEMRDCYATQRTGFAFEVQDLKLLVYRDQQNDCVNKENVGSSFTDKHQTPEKSPVPMIEKNLMCELDDDCDKNSKKDYLSSSFLCSDGDRTPKSIHMDSDSSFPGISIMESPLGGQSLDPDKNIKESSLEESNIEDLLPVSPSCQESTLPKGVECPTIQDSNQKMLAPSSEVLKPLTSKRNAVAFRSFNSHINASNSSEPSKMSITSLDMMDVSCAYSGSYPTAITPTQRERSDMPYQQTPNQVKSETPYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLARAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVDILLTIDDTKRAGMKGKKWDGDDSSMSKELRYLAMNCSH", "length": 853, "header": "tr|A0AAA9S9S4-1|G5E5K2_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase greatwall OS=Bos taurus OX=9913 GN=MASTL PE=3 SV=1 CANONICAL=G5E5K2-1" }, "locus": { "chromosome": "13", "start_pos": 17794079, "end_pos": 17750138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088336.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088336.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082836.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082836.1" } ] } }, { "isoform_ac": "A0AAA9SII0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SII0/entry", "sequence": { "sequence": "MEPTMGGEMESGGGAATGECVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGNRLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFHTPVAEGNHDTANVLSTQVSETSPLSQGLTCPMSVDQKDTTPYSSKLLKSCPEMVASHPRMPVKCLTSHLLQSRKRLATSSTSSPSHTFISSMESECHSSPRWEKDCQESDDAAGSTMMSWNTVEKPLCTKSVDAMETKSFNERDLELALSPIHNSSVVPATGNSYVNLAKKCSSGEVSWEARELDVNNINMTADTSQYCFHESNQRAVDSGGMTEEHLGKRSCKRIFELVDSSPRQGIIPNKKSCFEYECSNEMRDCYATQRTGFAFEVQDLKLLVYRDQQNDCVNKENVGSSFTDKHQTPEKSPVPMIEKNLMCELDDDCDKNSKKDYLSSSFLCSDGDRTPKSIHMDSDSSFPGISIMESPLGGQSLDPDKNIKESSLEESNIEDLLPVSPSCQESTLPKGVECPTIQDSNQKMLAPSSEVLKPLTSKRNAVAFRSFNSHINASNSSEPSKMSITSLDMMDVSCAYSGSYPTAITPTQRERSDMPYQQTPNQVKSETPYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLARAHDIPWPEGEEKLSDNAQSAVDILLTIDDTKRAGMKELKHHPLFSGVDWENLQHQKMPFIPQPDDETDTSYFEARNNAQHLTVSGFSL", "length": 843, "header": "tr|A0AAA9SII0-1|G5E5K2_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase greatwall OS=Bos taurus OX=9913 GN=MASTL PE=3 SV=1 CANONICAL=G5E5K2-1" }, "locus": { "chromosome": "13", "start_pos": 17772644, "end_pos": 17750138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129759.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129759.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083557.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083557.1" } ] } }, { "isoform_ac": "A0AAA9SJ54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ54/entry", "sequence": { "sequence": "MEPTMGGEMESGGGAATGECVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGNRLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFHTPVAEGNHDTANVLSTQVSETSPLSQGLTCPMSVDQKDTTPYSSKLLKSCPEMVASHPRMPVKCLTSHLLQSRKRLATSSTSSPSHTFISSMESECHSSPRWEKDCQESDDAAGSTMMSWNTVEKPLCTKSVDAMETKSFNERDLELALSPIHNSSVVPATGNSYVNLAKKCSSGEVSWEARELDVNNINMTADTSQYCFHESNQRAVDSGGMTEEHLGKRSCKRIFELVDSSPRQGIIPNKKSCFEYECSNEMRDCYATQRTGFAFEVQDLKLLVYRDQQNDCVNKENVGSSFTDKHQTPEKSPVPMIEKNLMCELDDDCDKNSKKDYLSSSFLCSDGDRTPKSIHMDSDSSFPGISIMESPLGGQSLDPDKNIKESSLEESNIEDLLPVSPSCQESTLPKGVECPTIQDSNQKMLAPSSEVLKPLTSKRNAVAFRSFNSHINASNSSEPSKMSITSLDMMDVSCAYSGSYPTAITPTQRERSDMPYQQTPNQVKSETPYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLARAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVDILLTIDDTKRAGMKGLE", "length": 832, "header": "tr|A0AAA9SJ54-1|G5E5K2_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase greatwall OS=Bos taurus OX=9913 GN=MASTL PE=3 SV=1 CANONICAL=G5E5K2-1" }, "locus": { "chromosome": "13", "start_pos": 17786468, "end_pos": 17750138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120725.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120725.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082603.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082603.1" } ] } }, { "isoform_ac": "A0AAA9TM22-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM22/entry", "sequence": { "sequence": "MEPTMGGEMESGGGAATGECVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGNRLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFHTPVAEGNHDTANVLSTQVSETSPLSQGLTCPMSVDQKDTTPYSSKLLKSCPEMVASHPRMPVKCLTSHLLQSRKRLATSSTSSPSHTFISSMESECHSSPRWEKDCQESDDAAGSTMMSWNTVEKPLCTKSVDAMETKSFNERDLELALSPIHNSSVVPATGNSYVNLAKKCSSGEVSWEARELDVNNINMTADTSQYCFHESNQRAVDSGGMTEEHLGKRSCKRIFELVDSSPRQGIIPNKKSCFEYECSNEMRDCYATQRTGFAFEVQDLKLLVYRDQQNDCVNKENVGSSFTDKHQTPEKSPVPMIEKNLMCELDDDCDKNSKKDYLSSSFLCSDGDRTPKSIHMDSDSSFPGISIMESPLGGQSLDPDKNIKESSLEESNIEDLLPVSPSCQESTLPKGVECPTIQDSNQKMLAPSSEVLKPLTSKRNAVAFRSFNSHINASNSSEPSKMSITSLDMMDVSCAYSGSYPTAITPTQRERSDMPYQQTPNQVKSETPYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLARAHGFLTSGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVDILLTIDDTKRAGMKELKHHPLFSGVDWENLQHQKMPFIPQPDDETDTSYFEARNNAQHLTVSGFSL", "length": 886, "header": "tr|A0AAA9TM22-1|G5E5K2_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase greatwall OS=Bos taurus OX=9913 GN=MASTL PE=3 SV=1 CANONICAL=G5E5K2-1" }, "locus": { "chromosome": "13", "start_pos": 17772644, "end_pos": 17750138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135088.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135088.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099512.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099512.1" } ] } }, { "isoform_ac": "A0AAA9TRD8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRD8/entry", "sequence": { "sequence": "MEPTMGGEMESGGGAATGECVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGNRLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFHTPVAEGNHDTANVLSTQVSETSPLSQGLTCPMSVDQKDTTPYSSKLLKSCPEMVASHPRMPVKCLTSHLLQSRKRLATSSTSSPSHTFISSMESECHSSPRWEKDCQESDDAAGSTMMSWNTVEKPLCTKSVDAMETKSFNERDLELALSPIHNSSVVPATGNSYVNLAKKCSSGEVSWEARELDVNNINMTADTSQYCFHESNQRAVDSGGMTEEHLGKRSCKRIFELVDSSPRQGIIPNKKSCFEYECSNEMRDCYATQRTGFAFEVQDLKLLVYRDQQNDCVNKENVGSSFTDKHQTPEKSPVPMIEKNLMCELDDDCDKNSKKDYLSSSFLCSDGDRTPKSIHMDSDSSFPGISIMESPLGGQSLDPDKNIKESSLEESNIEDLLPVSPSCQESTLPKGVECPTIQDSNQKMLAPSSEVLKPLTSKRNAVAFRSFNSHINASNSSEPSKMSITSLDMMDVSCAYSGSYPTAITPTQRERSDMPYQQTPNQVKSETPYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLARAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVDILLTIDDTKRAGMKGSTADKTRQMQKPTCDAASISSLWSLWRTFCMSSCRRMSTSAICSFRLPLEPLSEPQRSPSPPLPTCRPLLPSLKCCILCPILRDQNKLLFGSVVKNPPANARHTDLIPGSRGSPGAGNSNPLPYSCLGNSMDRGAWWATVHGVAKEGHDLAPKQQQQS", "length": 988, "header": "tr|A0AAA9TRD8-1|G5E5K2_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase greatwall OS=Bos taurus OX=9913 GN=MASTL PE=3 SV=1 CANONICAL=G5E5K2-1" }, "locus": { "chromosome": "13", "start_pos": 17792051, "end_pos": 17750138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127302.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127302.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101171.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101171.1" } ] } }, { "isoform_ac": "G5E5K2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5K2/entry", "sequence": { "sequence": "MEPTMGGEMESGGGAATGECVNRIPVPRPPSIEEFTIVKPISRGAFGKVYLGQKGNRLYAVKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFHTPVAEGNHDTANVLSTQVSETSPLSQGLTCPMSVDQKDTTPYSSKLLKSCPEMVASHPRMPVKCLTSHLLQSRKRLATSSTSSPSHTFISSMESECHSSPRWEKDCQESDDAAGSTMMSWNTVEKPLCTKSVDAMETKSFNERDLELALSPIHNSSVVPATGNSYVNLAKKCSSGEVSWEARELDVNNINMTADTSQYCFHESNQRAVDSGGMTEEHLGKRSCKRIFELVDSSPRQGIIPNKKSCFEYECSNEMRDCYATQRTGFAFEVQDLKLLVYRDQQNDCVNKENVGSSFTDKHQTPEKSPVPMIEKNLMCELDDDCDKNSKKDYLSSSFLCSDGDRTPKSIHMDSDSSFPGISIMESPLGGQSLDPDKNIKESSLEESNIEDLLPVSPSCQESTLPKGVECPTIQDSNQKMLAPSSEVLKPLTSKRNAVAFRSFNSHINASNSSEPSKMSITSLDMMDVSCAYSGSYPTAITPTQRERSDMPYQQTPNQVKSETPYRTPKSVRRGAAPVDDGRILGTPDYLAPELLLARAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVDILLTIDDTKRAGMKELKHHPLFSGVDWENLQHQKMPFIPQPDDETDTSYFEARNNAQHLTVSGFSL", "length": 881, "header": "tr|G5E5K2-1|G5E5K2_BOVIN Isoform 1 of Serine/threonine-protein kinase greatwall OS=Bos taurus OX=9913 GN=MASTL PE=3 SV=2 CANONICAL=G5E5K2-1" }, "locus": { "chromosome": "13", "start_pos": 17772644, "end_pos": 17750138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022950.8", "url": "https://www.ensembl.org/id/ENSBTAT00000022950.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022950.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022950.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-2465910", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2465910", "resource": "Reactome", "description": "MASTL Facilitates Mitotic Progression" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "G5E5K2", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-BTA-2168079", "name": "MASTL (GWL) phosphorylates ARPP19", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-2160959" ], "output_participant_list": [ "R-BTA-2168081" ], "enzyme_list": [ "G5E5K2-1" ], "evidence": [ { "id": "R-BTA-2168079", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2168079" } ] }, { "id": "R-BTA-2430535", "name": "MASTL phosphorylates ENSA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-2160964" ], "output_participant_list": [ "R-BTA-2430532" ], "enzyme_list": [ "G5E5K2-1" ], "evidence": [ { "id": "R-BTA-2430535", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2430535" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-2160959", "participant_name": "ARPP19 [nucleoplasm]", "crossref": [ { "id": "Q28055", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000011022", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000106792", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000147167", "database": "ENSEMBL", "url": "" }, { "id": "NP_777130.1", "database": "RefSeq", "url": "" }, { "id": "XP_010807630.1", "database": "RefSeq", "url": "" }, { "id": "XP_059746217.1", "database": "RefSeq", "url": "" }, { "id": "NP_001106726.1", "database": "RefSeq", "url": "" }, { "id": "26167", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-2160964", "participant_name": "ENSA [nucleoplasm]", "crossref": [ { "id": "A0A140T869", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000007123", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000009379", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000009379", "database": "ENSEMBL", "url": "" }, { "id": "NP_001300934.1", "database": "RefSeq", "url": "" }, { "id": "50171", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-2168081", "participant_name": "phospho-ARPP19 [nucleoplasm]", "crossref": [ { "id": "ENSBTAT00000147167", "database": "ENSEMBL", "url": "" }, { "id": "NP_001106726.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000011022", "database": "ENSEMBL", "url": "" }, { "id": "XP_010807630.1", "database": "RefSeq", "url": "" }, { "id": "26167", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000106792", "database": "ENSEMBL", "url": "" }, { "id": "XP_059746217.1", "database": "RefSeq", "url": "" }, { "id": "Q28055", "database": "UniProt", "url": "" }, { "id": "NP_777130.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-2430532", "participant_name": "phospho-ENSA [nucleoplasm]", "crossref": [ { "id": "ENSBTAT00000009379", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAG00000007123", "database": "ENSEMBL", "url": "" }, { "id": "50171", "database": "VGNC", "url": "" }, { "id": "A0A140T869", "database": "UniProt", "url": "" }, { "id": "NP_001300934.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAP00000009379", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": 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"A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": 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"id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511413", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511413", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HCEIEIA", "url": "https://omabrowser.org/oma/group/HCEIEIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LG39", "url": "https://www.orthodb.org/?gene=A0A3Q1LG39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MI64", "url": "https://www.orthodb.org/?gene=A0A3Q1MI64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q05B78", "url": "https://www.orthodb.org/?gene=Q05B78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39490:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39490:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16696", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001073055", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073055", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LG39", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LG39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MI64", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MI64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZFH0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZFH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZFH0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZFH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B78", "url": "https://www.uniprot.org/uniprotkb/Q05B78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B78-1", "url": "https://www.uniprot.org/uniprotkb/Q05B78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSEVAARRDAKKLVRSPSGLRMVPEHRAYGSPFGLEEPPWVPDKECPRCMQCDTKFDFLTRKHHCRRCGKCFCDKCCGQKVALRRMCFVDPVRQCAGCAPVSRREADFYDRQLKLLLSGATFLVTFENSEKPDTMVCRLSSNQRFLLLDGDGDGDGHREVEVARIAAVQMLTEGLPPGDTLSHTSLPASRPAAEGGNARAIGMTLQYTTPGAEGLTQLTLTAGEDADGSRRQATAWLAAMHKAAKLLYESRDQ", "length": 254, "header": "sp|Q05B78-1|ZFY21_BOVIN Isoform 1 of Zinc finger FYVE domain-containing protein 21 OS=Bos taurus OX=9913 GN=ZFYVE21 PE=2 SV=1 CANONICAL=Q05B78-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LG39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG39/entry", "sequence": { "sequence": "MRQSEEKRSPRRRLTGQSEVSVAPTGWGVLGRVLADHWWPAAGGRGRRSCVDWSTRRRGGSLAPIGPRSGPGVATGRERCQPCWRGGAGLPWGSGRAAGGGRRAAGGGRRAAGERSGGVMSSEVAARRDAKKLVRSPSGLRMVPEHRAYGSPFGLEEPPWVPDKECPRCMQCDTKFDFLTRKHHCRRCGKCFCDKCCGQKVALRRMCFVDPVRQCAGCAPVSRREADFYDRQLKLLLSGATFLVTFENSEKPDTMVCRLSSNQRFLLLDGDGDGDGHREVEVARIAAVQMLTEGLPPGDTLSHTSLPASRPAAEGGNARAIGMTLQYTTPGAEGLTQLTLTAGEDADGSRRQATAWLAAMHKAAKLLYESRDQ", "length": 373, "header": "tr|A0A3Q1LG39-1|ZFY21_BOVIN Computationally mapped isoform of Zinc finger FYVE domain-containing protein 21 OS=Bos taurus OX=9913 GN=ZFYVE21 PE=2 SV=2 CANONICAL=Q05B78-1" }, "locus": { "chromosome": "21", "start_pos": 68328158, "end_pos": 68317958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086234.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086234.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057309.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057309.2" } ] } }, { "isoform_ac": "A0A3Q1MI64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI64/entry", "sequence": { "sequence": "MRQSEEKRSPRRRLTGQSEVSVAPTGWGVLGRVLADHWWPAAGGRGRRSCVDWSTRRRGGSLAPIGPRSGPGVATGRERCQPCWRGGAGLPWGSGRAAGGGRRAAGGGRRAAGERSGGVMSSEVAARRDAKKLVRSPSGLRMVPEHRAYGSPFGLEEPPWVPDKECPRCMQCDTKFDFLTRKHHCRRCGKCFCDKCCGQKVALRRMCFVDPVRQCAGCAPVSRREADFYDRQLKLLLSGATFLVTFENSEKPDTMVCRLSSNQRFLLLDGDGDGDGHREVEVARIAAVQMLTEGLPPGGGNARAIGMTLQYTTPGAEGLTQLTLTAGEDADGSRRQATAWLAAMHKAAKLLYESRDQ", "length": 357, "header": "tr|A0A3Q1MI64-1|ZFY21_BOVIN Computationally mapped isoform of Zinc finger FYVE domain-containing protein 21 OS=Bos taurus OX=9913 GN=ZFYVE21 PE=2 SV=2 CANONICAL=Q05B78-1" }, "locus": { "chromosome": "21", "start_pos": 68328158, "end_pos": 68317958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073944.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073944.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073980.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073980.2" } ] } }, { "isoform_ac": "A0AAF6ZFH0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZFH0/entry", "sequence": { "sequence": "MSSEVAARRDAKKLVRSPSGLRMVPEHRAYGSPFGLEEPPWVPDKECPRCMQCDTKFDFLTRKHHCRRCGKCFCDKCCGQKVALRRMCFVDPVRQCAGCAPVSRREADFYDRQLKLLLSGATFLVTFENSEKPDTMVCRLSTSEGRGTDVEVARIAAVQMLTEGLPPGDTLSHTSLPASRPAAEGGNARAIGMTLQYTTPGAEGLTQLTLTAGEDADGSRRQATAWLAAMHKAAKLLYESRDQ", "length": 243, "header": "tr|A0AAF6ZFH0-1|ZFY21_BOVIN Computationally mapped isoform of Zinc finger FYVE domain-containing protein 21 OS=Bos taurus OX=9913 GN=ZFYVE21 PE=2 SV=1 CANONICAL=Q05B78-1" }, "locus": { "chromosome": "21", "start_pos": 68328158, "end_pos": 68318315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044457.6", "url": "https://www.ensembl.org/id/ENSBTAT00000044457.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041951.5", "url": "https://www.ensembl.org/id/ENSBTAP00000041951.5" } ] } }, { "isoform_ac": "Q05B78-1", "url": "https://www.uniprot.org/uniprotkb/Q05B78/entry#Q05B78-1", "sequence": { "sequence": "MSSEVAARRDAKKLVRSPSGLRMVPEHRAYGSPFGLEEPPWVPDKECPRCMQCDTKFDFLTRKHHCRRCGKCFCDKCCGQKVALRRMCFVDPVRQCAGCAPVSRREADFYDRQLKLLLSGATFLVTFENSEKPDTMVCRLSSNQRFLLLDGDGDGDGHREVEVARIAAVQMLTEGLPPGDTLSHTSLPASRPAAEGGNARAIGMTLQYTTPGAEGLTQLTLTAGEDADGSRRQATAWLAAMHKAAKLLYESRDQ", "length": 254, "header": "sp|Q05B78-1|ZFY21_BOVIN Isoform 1 of Zinc finger FYVE domain-containing protein 21 OS=Bos taurus OX=9913 GN=ZFYVE21 PE=2 SV=1 CANONICAL=Q05B78-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511413", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511413", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BE50-1", "protein_name": "Zinc finger FYVE-type containing 21", "gene_name": "ZFYVE21", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSEVAARRDAKKLVRSPSGLRMVPEHRAFGSPFGLEEPQWVPDKECPRCMQCGAKFDFLTRKHHCRRCGKCFCDKCCSQKVALRRMCFVDPVRQCAECALVSHREAEFFDKQLKVLLSGATFLVTFGHSEKPETMVCRLSNNQRFLLLDGSSRHEVEIARISAVQMLSEGFPPGGGNARATGMSLQYPAPGAEGVTQLKLTAGEDANGSRRQATAWLAAMHKAAKLLYESRDQ", "length": 234 }, "evidence": [ { "id": "Q05B78", "url": "https://omabrowser.org/oma/group/Q05B78/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YUS1-1", "protein_name": "Zinc finger FYVE-type containing 21", "gene_name": "ZFYVE21", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGCEARDAKKLVRSLSGLRMVPEHRSARSPFGLDEPPWVPDKECPRCMQCDTKFDFITRKHHCRRCGKCFCDKCCSKKVPLPRMCFVDPVRQCAECALISQKETEFYDKQLKVLMNGATFFVTLGTSDKSELMVCRLSNNQRYLVLDGNSHYEIEIVQISTVQILTEGFTPGEKDIHTYTSLLESQHITEGGNTRAIGMILHYKVPGSEELTQMKFTASEDFSSNKKLSASWLAAMHKATKLLYESRDQ", "length": 250 }, "evidence": [ { "id": "Q05B78", "url": "https://omabrowser.org/oma/group/Q05B78/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B8A6I2-1", "protein_name": "Zinc finger FYVE domain-containing protein 21 isoform X1", "gene_name": "zfyve21", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAVPDGKKLVRSPSGLRMVPENGAFNSPFTLDEPQWVPDKECPRCMQCDTKFDFITRKHHCRRCGRCFCDKCCSQKVALPRMCFVDPVRQCAECSLISQKEVEFYDKQLKVLTAGGTFVVKVGSSEKSETMVCRLSNNHRYLFLDGNSHFEVELSRISSMQVLTEGSTPGEKDICSYTSLLDNQISEGGTLRASGMVLQYKPPGSLDLQQLNMDTADDKRIASAWLAAMHKAAKLLYESKDQ", "length": 243 }, "evidence": [ { "id": "Q05B78", "url": "https://omabrowser.org/oma/group/Q05B78/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VCM3-1", "protein_name": "Zinc finger FYVE domain-containing protein 21", "gene_name": "Zfyve21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGVAARRDAKKLVRSPSGLRMVPEHRAFGSPFGLEEPQWVPDKECPRCMQCDAKFDFITRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCADCALVSHREAEFYDKQLKVLLSGATFLVTFGDSEKPETMVCRLSNNQRCLVLDGDSHREIEIAHVCTVQILTEGFTPGAGSTRATGMLLQYTVPGAEAAAQLRLMAGEDASGSKRQAAAWLAAMHKATKLLYESRDQ", "length": 234 }, "evidence": [ { "id": "Q05B78", "url": "https://omabrowser.org/oma/group/Q05B78/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQ24-1", "protein_name": "Zinc finger FYVE domain-containing protein 21", "gene_name": "ZFYVE21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSEVSARRDAKKLVRSPSGLRMVPEHRAFGSPFGLEEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAECALVSLKEAEFYDKQLKVLLSGATFLVTFGNSEKPETMTCRLSNNQRYLFLDGDSHYEIEIVHISTVQILTEGFPPGGGNARATGMFLQYTVPGTEGVTQLKLTVVEDVTVGRRQAVAWLVAMHKAAKLLYESRDQ", "length": 234 }, "evidence": [ { "id": "Q05B78", "url": "https://omabrowser.org/oma/group/Q05B78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q05B78", "url": "https://www.uniprot.org/uniprotkb/Q05B78" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "Q05B78", "url": "https://www.uniprot.org/uniprotkb/Q05B78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q05B78", "url": "https://www.uniprot.org/uniprotkb/Q05B78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q05B78-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 254, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q05B78-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q05B78" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "Q05B78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B78" }, { "id": "PRU00091", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00091" } ], "binding_site_uniprot": 50, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 50, "end_pos": 50, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q05B78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B78" }, { "id": "PRU00091", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00091" } ], "binding_site_uniprot": 53, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 53, "end_pos": 53, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q05B78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B78" }, { "id": "PRU00091", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00091" } ], "binding_site_uniprot": 66, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 66, "end_pos": 66, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q05B78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B78" }, { "id": "PRU00091", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00091" } ], "binding_site_uniprot": 69, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 69, "end_pos": 69, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q05B78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B78" }, { "id": "PRU00091", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00091" } ], "binding_site_uniprot": 74, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 74, "end_pos": 74, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q05B78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B78" }, { "id": "PRU00091", "database": 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"https://prosite.expasy.org/PRU00091" } ], "binding_site_uniprot": 99, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 99, "end_pos": 99, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"sequence": "MKGESLPRVFPLVSCMSSPSDESTVALGCLAQDFMPNSVSFSWKFNNSTVSSERFWTFPAVLRDGLWSASSQVVLPSSSTFQGPDDYLVCEVQHPKGGKTVGTVRVVTPKAEVLSPIVSVFVPPRNSLSGDGNSKSSLICQATDFSPKQISLSWFRDGKRIVSGISEGQVETVQSSPITFRAYSMLTITEKDWLSQNVYTCQVEHNKETFQKNVSSSCDAAPPSPIGVFTIPPSFADIFLTKSAKLSCLVTNLASYDGLNISWSRQNGKALETHTYFERHLNDTFSARGEASVCSEDWESGEEFTCTVAHSDLPFPEKNAVSKPKDVAMKPPSVYLLPPTREQLSLRESASVTCLVKGFAPADVFVQWLQRGEPVTKSKYVTSSPAPEPQDPSVYFVHSILTVAEEDWSKGETYTCVVGHEALPHMVTERTVDKSTEGEVSAEEEGFENLNTMASTFIVLFLLSLFYSTTVTLFKVGRLVPGRG", "length": 484, "header": "tr|A0A3Q1LPI6-1|G5E5T5_BOVIN Computationally mapped isoform of Ig mu chain C region OS=Bos taurus OX=9913 GN= PE=1 SV=3 CANONICAL=G5E5T5-1" }, "locus": { "chromosome": "21", "start_pos": 203458, "end_pos": 198681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079313.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079313.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061989.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061989.3" } ] } }, { "isoform_ac": "G5E5T5-1", "url": "https://www.uniprot.org/uniprotkb/G5E5T5/entry", "sequence": { "sequence": "MVSLWRLEMGWGPRRLEPRQAPEVFVGRGWRYHHCVYYGIDAWGRGLRVTVSSEGESLPRVFPLVSCMSSPSDESTVALGCLAQDFMPNSVSFSWKFNNSTVSSERFWTFPAVLRDGLWSASSQVVLPSSSTFQGPDDYLVCEVQHPKGGKTVGTVRVVTPKAEVLSPIVSVFVPPRNSLSGDGNSKSSLICQATDFSPKQISLSWFRDGKRIVSGISEGQVETVQSSPITFRAYSMLTITEKDWLSQNVYTCQVEHNKETFQKNVSSSCDAAPPSPIGVFTIPPSFADIFLTKSAKLSCLVTNLASYDGLNISWSRQNGKALETHTYFERHLNDTFSARGEASVCSEDWESGEEFTCTVAHSDLPFPEKNAVSKPKDVAMKPPSVYLLPPTREQLSLRESASVTCLVKGFAPADVFVQWLQRGEPVTKSKYVTSSPAPEPQDPSVYFVHSILTVAEEDWSKGETYTCVVGHEALPHMVTERTVDKSTEGEVSAEEEGFENLNTMASTFIVLFLLSLFYSTTVTLFKVK", "length": 529, "header": "tr|G5E5T5-1|G5E5T5_BOVIN Isoform 1 of Ig mu chain C region OS=Bos taurus OX=9913 GN= PE=1 SV=3 CANONICAL=G5E5T5-1" }, "locus": { "chromosome": "21", "start_pos": 206914, "end_pos": 198601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030542.7", "url": "https://www.ensembl.org/id/ENSBTAT00000030542.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030521.6", "url": "https://www.ensembl.org/id/ENSBTAP00000030521.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P01871-2", "protein_name": "Immunoglobulin heavy constant mu", "gene_name": "IGHM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "GSASAPTLFPLVSCENSPSDTSSVAVGCLAQDFLPDSITFSWKYKNNSDISSTRGFPSVLRGGKYAATSQVLLPSKDVMQGTDEHVVCKVQHPNGNKEKNVPLPVIAELPPKVSVFVPPRDGFFGNPRKSKLICQATGFSPRQIQVSWLREGKQVGSGVTTDQVQAEAKESGPTTYKVTSTLTIKESDWLGQSMFTCRVDHRGLTFQQNASSMCVPDQDTAIRVFAIPPSFASIFLTKSTKLTCLVTDLTTYDSVTISWTRQNGEAVKTHTNISESHPNATFSAVGEASICEDDWNSGERFTCTVTHTDLPSPLKQTISRPKGVALHRPDVYLLPPAREQLNLRESATITCLVTGFSPADVFVQWMQRGQPLSPEKYVTSAPMPEPQAPGRYFAHSILTVSEEEWNTGETYTCVVAHEALPNRVTERTVDKSTEGEVSADEEGFENLWATASTFIVLFLLSLFYSTTVTLFKVK", "length": 474 }, "evidence": [ { "id": "G5E5T5", "url": "https://omabrowser.org/oma/group/G5E5T5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P01872-1", "protein_name": "Immunoglobulin heavy constant mu", "gene_name": "Ighm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "SQSFPNVFPLVSCESPLSDKNLVAMGCLARDFLPSTISFTWNYQNNTEVIQGIRTFPTLRTGGKYLATSQVLLSPKSILEGSDEYLVCKIHYGGKNRDLHVPIPAVAEMNPNVNVFVPPRDGFSGPAPRKSKLICEATNFTPKPITVSWLKDGKLVESGFTTDPVTIENKGSTPQTYKVISTLTISEIDWLNLNVYTCRVDHRGLTFLKNVSSTCAASPSTDILTFTIPPSFADIFLSKSANLTCLVSNLATYETLNISWASQSGEPLETKIKIMESHPNGTFSAKGVASVCVEDWNNRKEFVCTVTHRDLPSPQKKFISKPNEVHKHPPAVYLLPPAREQLNLRESATVTCLVKGFSPADISVQWLQRGQLLPQEKYVTSAPMPEPGAPGFYFTHSILTVTEEEWNSGETYTCVVGHEALPHLVTERTVDKSTGKPTLYNVSLIMSDTGGTCY", "length": 454 }, "evidence": [ { "id": "G5E5T5", "url": "https://omabrowser.org/oma/group/G5E5T5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], 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"name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 98, "end_pos": 100 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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Classification" ] }, { "id": "PF14967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005227523", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227523", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T458", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T458", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T458-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T458-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZB9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZB9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5J9", "url": "https://www.uniprot.org/uniprotkb/G5E5J9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5J9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5J9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHQSLTQQRSSDMSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLVENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVPKTSQKEAEEVNCPHLSRGFCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNPTLPALNCSVENAHPTVSYYARPQVASYNTYYHSPPHLPPYSAYDFQHSSAFPSSPPSGLSDEPQSASPSPSYMWSSSAPPRYSPPYYPPFEKPPPYSP", "length": 325, "header": "tr|G5E5J9-1|G5E5J9_BOVIN Isoform 1 of Transmembrane protein 255A OS=Bos taurus OX=9913 GN=TMEM255A PE=3 SV=1 CANONICAL=G5E5J9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T458-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T458/entry", "sequence": { "sequence": "MVNCPHLSRGFCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNPTLPALNCSVENAHPTVSYYARPQVASYNTYYHSPPHLPPYSAYDFQHSSAFPSSPPSGLSDEPQSASPSPSYMWSSSAPPRYSPPYYPPFEKPPPYSP", "length": 185, "header": "tr|A0AAA9T458-1|G5E5J9_BOVIN Computationally mapped isoform of Transmembrane protein 255A OS=Bos taurus OX=9913 GN=TMEM255A PE=3 SV=1 CANONICAL=G5E5J9-1" }, "locus": { "chromosome": "X", "start_pos": 4851146, "end_pos": 4830046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096361.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096361.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091440.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091440.1" } ] } }, { "isoform_ac": "A0AAA9TZB9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZB9/entry", "sequence": { "sequence": "MHQSLTQQRSSDMSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLVENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVPKTSQKEAEENPTLPALNCSVENAHPTVSYYARPQVASYNTYYHSPPHLPPYSAYDFQHSSAFPSSPPSGLSDEPQSASPSPSYMWSSSAPPRYSPPYYPPFEKPPPYSP", "length": 241, "header": "tr|A0AAA9TZB9-1|G5E5J9_BOVIN Computationally mapped isoform of Transmembrane protein 255A OS=Bos taurus OX=9913 GN=TMEM255A PE=3 SV=1 CANONICAL=G5E5J9-1" }, "locus": { "chromosome": "X", "start_pos": 4875707, "end_pos": 4830046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134096.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134096.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103663.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103663.1" } ] } }, { "isoform_ac": "G5E5J9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5J9/entry", "sequence": { "sequence": "MHQSLTQQRSSDMSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLVENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVPKTSQKEAEEVNCPHLSRGFCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNPTLPALNCSVENAHPTVSYYARPQVASYNTYYHSPPHLPPYSAYDFQHSSAFPSSPPSGLSDEPQSASPSPSYMWSSSAPPRYSPPYYPPFEKPPPYSP", "length": 325, "header": "tr|G5E5J9-1|G5E5J9_BOVIN Isoform 1 of Transmembrane protein 255A OS=Bos taurus OX=9913 GN=TMEM255A PE=3 SV=1 CANONICAL=G5E5J9-1" }, "locus": { "chromosome": "X", "start_pos": 4875707, "end_pos": 4830046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022841.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022841.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022841.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022841.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E5J9", "url": "https://www.uniprot.org/uniprotkb/G5E5J9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], 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"total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. 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"Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LU10", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LU10-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M203", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M203", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M203-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M203-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI13", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNT7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNT7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAGRAARQRRRRGPDSSPVLPAPPTTGHVVTGAEAAAAAAAAELRLRLAARILPSCARGARLRRGARSPGRRARSRLRSEGCRLPAPPCTPPAQRFSDTMATSRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASTSERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAVKPETSDHCSLPEDLRVSEVPNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRVTSDASPGKLEHPKAVPSVLVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLVLALWFTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGPDQHLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFTGVTVGRGAQIVNGCVNNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEEQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVILEKLAEGLDIRLRSPVQSIDYSGDEVQVTTTSGAVCTAQKVLVTVPLALLQKGAIQFNPPLSDKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKQHSVLMSVIAGEAVAAVRSLEDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDILAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 921, "header": "tr|A0A3Q1LGR3-1|A0A3Q1LGR3_BOVIN Isoform 1 of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Bos taurus OX=9913 GN=KDM1B PE=3 SV=2 CANONICAL=A0A3Q1LGR3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3/entry", "sequence": { "sequence": "MARAGRAARQRRRRGPDSSPVLPAPPTTGHVVTGAEAAAAAAAAELRLRLAARILPSCARGARLRRGARSPGRRARSRLRSEGCRLPAPPCTPPAQRFSDTMATSRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASTSERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAVKPETSDHCSLPEDLRVSEVPNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRVTSDASPGKLEHPKAVPSVLVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLVLALWFTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGPDQHLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFTGVTVGRGAQIVNGCVNNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEEQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVILEKLAEGLDIRLRSPVQSIDYSGDEVQVTTTSGAVCTAQKVLVTVPLALLQKGAIQFNPPLSDKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKQHSVLMSVIAGEAVAAVRSLEDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDILAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 921, "header": "tr|A0A3Q1LGR3-1|A0A3Q1LGR3_BOVIN Isoform 1 of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Bos taurus OX=9913 GN=KDM1B PE=3 SV=2 CANONICAL=A0A3Q1LGR3-1" }, "locus": { "chromosome": "23", "start_pos": 39431766, "end_pos": 39389857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076721.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076721.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057718.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057718.2" } ] } }, { "isoform_ac": "A0A3Q1LU10-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU10/entry", "sequence": { "sequence": "MATSRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASTSERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAVKPETSDHCSLPEDLRVSEVPNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRVTSDASPGKLEHPKAVPSVLVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLVLALWFTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGPDQHLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFTGVTVGRGAQIVNGCVNNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEEQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVILEKLAEGLDIRLRSPQVQSIDYSGDEVQVTTTSGAVCTAQKVLVTVPLALLQKGAIQFNPPLSDKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKQHSVLMSVIAGEAVAAVRSLEDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDILAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 821, "header": "tr|A0A3Q1LU10-1|A0A3Q1LGR3_BOVIN Computationally mapped isoform of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Bos taurus OX=9913 GN=KDM1B PE=3 SV=1 CANONICAL=A0A3Q1LGR3-1" }, "locus": { "chromosome": "23", "start_pos": 39427264, "end_pos": 39389857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083629.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083629.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063988.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063988.2" } ] } }, { "isoform_ac": "A0A3Q1M203-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M203/entry", "sequence": { "sequence": "MATSRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASTSERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAVKPETSDHCSLPEDLEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGPDQHLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFTGVTVGRGAQIVNGCVNNPVALMCEQVSARSWDHNEFFAQFAGDHTLLTPGYSVILEKLAEGLDIRLRSPVQSIDYSGDEVQVTTTSGAVCTAQKVLVTVPLALLQKGAIQFNPPLSDKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKQHSVLMSVIAGEAVAAVRSLEDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDILAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 590, "header": "tr|A0A3Q1M203-1|A0A3Q1LGR3_BOVIN Computationally mapped isoform of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Bos taurus OX=9913 GN=KDM1B PE=3 SV=1 CANONICAL=A0A3Q1LGR3-1" }, "locus": { "chromosome": "23", "start_pos": 39427264, "end_pos": 39389857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074786.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074786.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064014.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064014.1" } ] } }, { "isoform_ac": "A0AAA9TI13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI13/entry", "sequence": { "sequence": "MLLFNVFWFVFCFVLCFFDRFSDTMATSRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASTSERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAVKPETSDHCSLPEDLRVSEVPNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRVTSDASPGKLEHPKAVPSVLVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLVLALWFTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGPDQHLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFTGVTVGRGAQIVNGCVNNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEEQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVILEKLAEGLDIRLRSPVQSIDYSGDEVQVTTTSGAVCTAQKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKQHSVLMSVIAGEAVAAVRSLEDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDILAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 805, "header": "tr|A0AAA9TI13-1|A0A3Q1LGR3_BOVIN Computationally mapped isoform of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Bos taurus OX=9913 GN=KDM1B PE=3 SV=2 CANONICAL=A0A3Q1LGR3-1" }, "locus": { "chromosome": "23", "start_pos": 39427336, "end_pos": 39389857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115190.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115190.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096555.2", "url": "https://www.ensembl.org/id/ENSBTAP00000096555.2" } ] } }, { "isoform_ac": "A0ABI0NNT7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNT7/entry", "sequence": { "sequence": "MATSRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASTSERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAVKPETSDHCSLPEDLRVSEVPNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRVTSDASPGKLEHPKAVPSVLVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLVLALWFTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGPDQHLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFTGVTVGRGAQIVNGCVNNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEEQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVILEKLAEGLDIRLRSPVQSIDYSGDEVQVTTTSGAVCTAQKVLVTVPLALLQKGAIQFNPPLSDKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKQHSVLMSVIAGEAVAAVRSLEDKQVLQQCMATLRELFKEQATNRHFPQTVTGAYLSGVREASKIAAF", "length": 769, "header": "tr|A0ABI0NNT7-1|A0ABI0NNT7_BOVIN Computationally mapped isoform of [histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase OS=Bos taurus OX=9913 GN=KDM1B PE=3 SV=1 CANONICAL=A0A3Q1LGR3-1" }, "locus": { "chromosome": "23", "start_pos": 39427264, "end_pos": 39389857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141528.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141528.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104461.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104461.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "FAD-dependent H3K4me/H3K4me3 demethylase activity", "id": "GO:0140682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140682", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60244", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MBS5-1", "A0A3Q1LGR3-1" ], "evidence": [ { "id": "60244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60244" } ] }, { "id": "60256", "name": "", "equation": "N(6)-methyl-L-lysyl(4)-[histone H3] + A + H2O = L-lysyl(4)-[histone H3] + formaldehyde + AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LGR3-1", "F1MBS5-1" ], "evidence": [ { "id": "60256", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60256" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGR3", "gene_name": "KDM1B", "activity": [ { "ec_number": "1.14.99.66", "activity": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2.", "evidence": [ { "id": "A0A3Q1LGR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ] }, { "ec_number": "1.14.99.66", "activity": "", "evidence": [ { "id": "A0A3Q1LGR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" } ] } ] }, { "uniprot_ac": "F1MBS5", "gene_name": "KDM1A", "activity": [ { "ec_number": "1.14.11.65", "activity": "N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "F1MBS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS5" } ] }, { "ec_number": "1.14.99.66", "activity": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2.", "evidence": [ { "id": "F1MBS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS5" } ] }, { "ec_number": "1.14.99.66", "activity": "", "evidence": [ { "id": "F1MBS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS5" } ] }, { "ec_number": "1.14.11.65", "activity": "", "evidence": [ { "id": "F1MBS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBS5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LGR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" }, { "id": "PS51050", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CW-type", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 294, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LGR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGR3" }, { "id": "PS50934", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50934" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SWIRM", "eco_id": "ECO_0000259", "start_pos": 374, "end_pos": 472, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.99.66", "ec_name": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2.", "evidence": [ { "id": "1.14.99.66", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.99.66" }, { "id": "1.14.99.66", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.99.66" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 481, "end_pos": 483 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LMM6-1", "uniprot_ac": "A0A3Q1LMM6", "uniprot_id": "A0A3Q1LMM6_BOVIN", "mass": { "chemical_mass": 50591.0, "monoisotopic_mass": 50591.0 }, "refseq": {}, "gene_names": [ { "name": "PARVA", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ] } ], "protein_names": [ { "name": "Parvin alpha", "type": "synonym", "evidence": [ { "id": "A0A3Q1LMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PARVA", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6", "locus": { "chromosome": "15", "start_pos": 40169482, "end_pos": 40347922, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000700", "url": "https://www.ensembl.org/id/ENSBTAG00000000700" } ] } } ], "crossref": [ { "id": "A0A3Q1LMM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000700", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000700", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21335", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21335", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VDLLIYW", "url": "https://omabrowser.org/oma/group/VDLLIYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-446343", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446343", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-446353", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446353", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-446388", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446388", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWL5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0Q4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJN2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRH7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4W6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4W6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB59", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB59-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QTA8", "url": "https://www.uniprot.org/uniprotkb/F6QTA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QTA8-1", "url": "https://www.uniprot.org/uniprotkb/F6QTA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGASSLLPAAAGAGPERSAPCRAEGGAREGEREGKGERELPRMLGIIPLPFGKPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEETLQMEVEDLQLDPHWNPPDDPG", "length": 453, "header": "tr|A0A3Q1LMM6-1|A0A3Q1LMM6_BOVIN Isoform 1 of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=2 CANONICAL=A0A3Q1LMM6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6/entry", "sequence": { "sequence": "MFGASSLLPAAAGAGPERSAPCRAEGGAREGEREGKGERELPRMLGIIPLPFGKPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEETLQMEVEDLQLDPHWNPPDDPG", "length": 453, "header": "tr|A0A3Q1LMM6-1|A0A3Q1LMM6_BOVIN Isoform 1 of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=2 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347320, "end_pos": 40190093, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081787.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081787.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061139.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061139.2" } ] } }, { "isoform_ac": "A0A3Q1LWL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWL5/entry", "sequence": { "sequence": "MFGASSLLPAAAGAGPERSAPCRAEGGAREGEREGKGERELPRMLGIIPLPFGKPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEVPQLLLSHV", "length": 439, "header": "tr|A0A3Q1LWL5-1|A0A3Q1LMM6_BOVIN Computationally mapped isoform of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=2 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347320, "end_pos": 40191502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067786.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067786.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061632.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061632.2" } ] } }, { "isoform_ac": "A0AAA9S0Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0Q4/entry", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKGLQWLNEGGRGDAQLSWEAATYRPLSIPPLHPRPLATPSCRGPQPSFIPPQR", "length": 375, "header": "tr|A0AAA9S0Q4-1|A0A3Q1LMM6_BOVIN Computationally mapped isoform of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=1 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347071, "end_pos": 40194605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104189.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104189.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075651.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075651.1" } ] } }, { "isoform_ac": "A0AAA9SJN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJN2/entry", "sequence": { "sequence": "MFGASSLLPAAAGAGPERSAPCRAEGGAREGEREGKGERELPRMLGIIPLPFGKPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 455, "header": "tr|A0AAA9SJN2-1|A0A3Q1LMM6_BOVIN Computationally mapped isoform of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=1 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347320, "end_pos": 40169974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087704.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087704.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086503.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086503.1" } ] } }, { "isoform_ac": "A0AAA9SRH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRH7/entry", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 338, "header": "tr|A0AAA9SRH7-1|A0A3Q1LMM6_BOVIN Computationally mapped isoform of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=2 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347071, "end_pos": 40169974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124855.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124855.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086678.2", "url": "https://www.ensembl.org/id/ENSBTAP00000086678.2" } ] } }, { "isoform_ac": "A0AAA9T4W6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4W6/entry", "sequence": { "sequence": "MFGASSLLPAAAGAGPERSAPCRAEGGAREGEREGKGERELPRMLGIIPLPFGKPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEGTLLFPGFVARGKTLPCTQAFTAESMIRV", "length": 459, "header": "tr|A0AAA9T4W6-1|A0A3Q1LMM6_BOVIN Computationally mapped isoform of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=1 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347320, "end_pos": 40193670, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097055.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097055.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091550.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091550.1" } ] } }, { "isoform_ac": "A0AAA9TB59-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB59/entry", "sequence": { "sequence": "MTFKLPTLEGVEEEVDSHDKSRTVGCAVRPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEVG", "length": 407, "header": "tr|A0AAA9TB59-1|A0A3Q1LMM6_BOVIN Computationally mapped isoform of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=1 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347723, "end_pos": 40186889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130922.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130922.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093908.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093908.1" } ] } }, { "isoform_ac": "F6QTA8-1", "url": "https://www.uniprot.org/uniprotkb/F6QTA8/entry", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEVTYMGKEVLKEWIYVY", "length": 363, "header": "tr|F6QTA8-1|A0A3Q1LMM6_BOVIN Computationally mapped isoform of Parvin alpha OS=Bos taurus OX=9913 GN=PARVA PE=3 SV=3 CANONICAL=A0A3Q1LMM6-1" }, "locus": { "chromosome": "15", "start_pos": 40347071, "end_pos": 40185450, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000935.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000935.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000935.7", "url": "https://www.ensembl.org/id/ENSBTAP00000000935.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-446343", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446343", "resource": "Reactome", "description": "Localization of the PINCH-ILK-PARVIN complex to focal adhesions" }, { "id": "R-BTA-446353", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446353", "resource": "Reactome", "description": "Cell-extracellular matrix interactions" }, { "id": "R-BTA-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B7K9-1", "protein_name": "Parvin alpha", "gene_name": "PARVA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "A0A3Q1LMM6", "url": "https://omabrowser.org/oma/group/A0A3Q1LMM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QGY3-1", "protein_name": "Alpha-parvin isoform X1", "gene_name": "Parva", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "A0A3Q1LMM6", "url": "https://omabrowser.org/oma/group/A0A3Q1LMM6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZN45-1", "protein_name": "Parvin alpha", "gene_name": "PARVA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASSPQKSPSSPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEAFSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "A0A3Q1LMM6", "url": "https://omabrowser.org/oma/group/A0A3Q1LMM6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9NVD7-1", "protein_name": "Alpha-parvin", "gene_name": "PARVA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "A0A3Q1LMM6", "url": "https://omabrowser.org/oma/group/A0A3Q1LMM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWD0-1", "protein_name": "Parvin, isoform A", "gene_name": "parvin", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTLNRPKSPHTPTAIKKGEKEDSFWDKFSTLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYALREHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKKLDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPVRLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRDFA", "length": 367 }, "evidence": [ { "id": "A0A3Q1LMM6", "url": "https://omabrowser.org/oma/group/A0A3Q1LMM6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity regulating cell shape", "id": "GO:0071963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071963", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMM6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMM6" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 285, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 248, "end_pos": 250 }, { "start_pos": 409, "end_pos": 411 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"Protein" ] }, { "id": "A0AAA9RUB4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUB4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G8JKV5", "url": "https://www.uniprot.org/uniprotkb/G8JKV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G8JKV5-1", "url": "https://www.uniprot.org/uniprotkb/G8JKV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINAKWAATRWAKKIEAREKKAKMTDFDRYKVMKARKMRNRLIKIEVKKLQKAALLKASPKKALAAKGAAAVAAAAAKVPAKKITTEGKKAPAQKAPAQKAAGQKAAPPPKTQKGQKAPSQKAPAPKASGKKA", "length": 213, "header": "tr|G8JKV5-1|G8JKV5_BOVIN Isoform 1 of Large ribosomal subunit protein eL14 OS=Bos taurus OX=9913 GN=RPL14 PE=3 SV=2 CANONICAL=G8JKV5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M8U2-1", 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"MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINAKWAATRWAKKIEAREKKAKMTDFDRYKVMKARKMRNRLIKIEVKKLQKAALLKASPKKALAAKGAAAVAAAAAKVPAKKITTEGKKAPAQKAAPPPKTQKGQKAPSQKAPAPKASGKKA", "length": 203, "header": "tr|A0AAA9RUB4-1|G8JKV5_BOVIN Computationally mapped isoform of Large ribosomal subunit protein eL14 OS=Bos taurus OX=9913 GN=RPL14 PE=3 SV=1 CANONICAL=G8JKV5-1" }, "locus": { "chromosome": "22", "start_pos": 13296054, "end_pos": 13292721, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096321.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096321.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076749.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076749.1" } ] } }, { "isoform_ac": "G8JKV5-1", "url": "https://www.uniprot.org/uniprotkb/G8JKV5/entry", "sequence": { "sequence": "AVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINAKWAATRWAKKIEAREKKAKMTDFDRYKVMKARKMRNRLIKIEVKKLQKAALLKASPKKALAAKGAAAVAAAAAKVPAKKITTEGKKAPAQKAPAQKAAGQKAAPPPKTQKGQKAPSQKAPAPKASGKKA", "length": 213, "header": "tr|G8JKV5-1|G8JKV5_BOVIN Isoform 1 of Large ribosomal subunit protein eL14 OS=Bos taurus OX=9913 GN=RPL14 PE=3 SV=2 CANONICAL=G8JKV5-1" }, "locus": { "chromosome": "22", "start_pos": 13296054, "end_pos": 13292832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002642.5", "url": "https://www.ensembl.org/id/ENSBTAT00000002642.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002642.4", "url": "https://www.ensembl.org/id/ENSBTAP00000002642.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156827", "resource": "Reactome", "description": 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Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74#function" }, { "database": "UniProtKB", "id": "ARBA00053613", "url": "https://www.uniprot.org/uniprotkb/ARBA00053613#function" }, { "database": "UniProtKB", "id": "A0A3Q1N960", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N960#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYTL4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74", "locus": { "chromosome": "X", "start_pos": 51477597, "end_pos": 51412034, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005724", "url": "https://www.ensembl.org/id/ENSBTAG00000005724" } ] } } ], "crossref": [ { "id": "A0A3Q1LN74", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LN74", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005724", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005724", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04020", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15764", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15764", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "515978", "url": "https://www.ncbi.nlm.nih.gov/gene/515978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515978", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIPSAKH", "url": "https://omabrowser.org/oma/group/YIPSAKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LN74", "url": "https://www.orthodb.org/?gene=A0A3Q1LN74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N960", "url": "https://www.orthodb.org/?gene=A0A3Q1N960", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02318", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02318", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN74-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N960", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N960", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N960-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N960-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEILDLSFLSEVERDLILSVLQRDEELRKADEKRIRRLKNDLLEIKRKGAKRGSQRYSNRTCARCQETLGRLTPKTNTCWSCNHLVCRDCRVQESNGTWRCKVCAKEIELKKATGDWFYDQKVNRFAYHTGSEIIRMSLRHKPAGTRPVGIWFLEVLDFSHRPSGVESKCILTGGVSSFIPWAQPICGQHKDYVAILSVSMLCSPSPTSPPSSPICHAFVCLEVNKRETVEQSLLHQSQLGDIWPGRKIIQEQQKEPSMSFEVPKLKSGRSVLEAESESLDSYTADSDTMSRRDSLDKSGLFPEWKKMSAPKPQVEKEAQLRGQNVVSVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVGHESGALGDRSKSVPGLSVDMEEEEEEEDIDHLVKLHRQKLARSSMRSGSSMSTIGSMMSIYSEAGDFGNIFVTGKIAFSLKYEQQTQALVIHVKECQQLAYADEAKKRSNPYVKAYLLPDKSRQGKRKTSIKQDTINPLYDEILRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEVQMDSWKLDKKLDHCLPLHGKISAESSTSLPAHKGELVVSLKYIPASKLPVGSDRKKSKGGEGGELQVWIKEAKNLTAAKLGGTSDSFVKGYLLPLRNKASKRKTPVVKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLSVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKLGL", "length": 750, "header": "tr|A0A3Q1LN74-1|A0A3Q1LN74_BOVIN Isoform 1 of Synaptotagmin-like protein 4 OS=Bos taurus OX=9913 GN=SYTL4 PE=4 SV=1 CANONICAL=A0A3Q1LN74-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LN74-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74/entry", "sequence": { "sequence": "MSEILDLSFLSEVERDLILSVLQRDEELRKADEKRIRRLKNDLLEIKRKGAKRGSQRYSNRTCARCQETLGRLTPKTNTCWSCNHLVCRDCRVQESNGTWRCKVCAKEIELKKATGDWFYDQKVNRFAYHTGSEIIRMSLRHKPAGTRPVGIWFLEVLDFSHRPSGVESKCILTGGVSSFIPWAQPICGQHKDYVAILSVSMLCSPSPTSPPSSPICHAFVCLEVNKRETVEQSLLHQSQLGDIWPGRKIIQEQQKEPSMSFEVPKLKSGRSVLEAESESLDSYTADSDTMSRRDSLDKSGLFPEWKKMSAPKPQVEKEAQLRGQNVVSVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVGHESGALGDRSKSVPGLSVDMEEEEEEEDIDHLVKLHRQKLARSSMRSGSSMSTIGSMMSIYSEAGDFGNIFVTGKIAFSLKYEQQTQALVIHVKECQQLAYADEAKKRSNPYVKAYLLPDKSRQGKRKTSIKQDTINPLYDEILRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEVQMDSWKLDKKLDHCLPLHGKISAESSTSLPAHKGELVVSLKYIPASKLPVGSDRKKSKGGEGGELQVWIKEAKNLTAAKLGGTSDSFVKGYLLPLRNKASKRKTPVVKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLSVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKLGL", "length": 750, "header": "tr|A0A3Q1LN74-1|A0A3Q1LN74_BOVIN Isoform 1 of Synaptotagmin-like protein 4 OS=Bos taurus OX=9913 GN=SYTL4 PE=4 SV=1 CANONICAL=A0A3Q1LN74-1" }, "locus": { "chromosome": "X", "start_pos": 51477435, "end_pos": 51443353, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074339.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074339.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058233.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058233.1" } ] } }, { "isoform_ac": "A0A3Q1N960-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N960/entry", "sequence": { "sequence": "MSEILDLSFLSEVERDLILSVLQRDEELRKADEKRIRRLKNDLLEIKRKGAKRGSQRYSNRTCARCQETLGRLTPKTNTCWSCNHLVCRDCRVQESNGTWRCKVCAKEIELKKATGDWFYDQKVNRFAYHTGSEIIRMSLRHKPAVNKRETVEQSLLHQSQLGDIWPGRKIIQEQQKEPSMSFEVPKLKSGRSVLEAESESLDSYTADSDTMSRRDSLDKSGLFPEWKKMSAPKPQVEKEAQLRGQNVVSVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVGHESGALGDRSKSVPGLSVDMEEEEEEEDIDHLVKLHRQKLARSSMRSGSSMSTIGSMMSIYSEAGDFGNIFVTGKIAFSLKYEQQTQALVIHVKECQQLAYADEAKKRSNPYVKAYLLPDKSRQGKRKTSIKQDTINPLYDEILRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEVQMDSWKLDKKLDHCLPLHGKISAESSTSLPAHKGELVVSLKYIPASKLPVGSDRKKSKGGEGGELQVWIKEAKNLTAAKLGGTSDSFVKGYLLPLRNKASKRKTPVVKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLSVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKLGL", "length": 671, "header": "tr|A0A3Q1N960-1|A0A3Q1LN74_BOVIN Computationally mapped isoform of Synaptotagmin-like protein 4 OS=Bos taurus OX=9913 GN=SYTL4 PE=4 SV=2 CANONICAL=A0A3Q1LN74-1" }, "locus": { "chromosome": "X", "start_pos": 51477435, "end_pos": 51443353, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078170.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078170.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067660.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067660.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515978", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9QP53-1", "protein_name": "Synaptotagmin-like protein 4", "gene_name": "sytl4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVQNMEINVSFLTDSEQEFILEVLRRDEDLRHLEDLRVKKLKAEFLDIRRKGAKRGSGKYSERSCGRCQEPLSLLSGSGSQCRSCKHQVCKKCQSVRPNGSWVCTVCAKEIDLKMSTGDWFFDERVNRFSSAPGHDLVRVSLRKRPLSKKHETAGEILLNKVELNPSQAAPVPKPRLKDIALANKSSLLEDEEGQQSDTESIEKASLDSDHAETKFSHSTPQMQRKEELRANSPEDCAVSILMSTVNSDSTATIETASLIHHMNACSDSLRDVDGLFKKSVRRVHKLSEIKPASTLDLREDASENTTPSMGDRSKSVPGLNADDEEEEEDIDNLVNIHRQKFGSSMGSLGGSRTTLGSMMSVYSEAGDYDHVEVSGEIVFSLSYDEPSQSLSVMVHECKGLAYADPAKKKCNPYVKAYLLPDKSKKKTSIKHNNINPSFKETLKYSISRTQLMTRTLQLSVWHYDRFGHNAFLGEVEVLMDSYDIDSAHEECMALRGKAVPQSLLSPFDQYKGELVISLKYVTPNAPNAEDSKGKGKKSKPADGSELHVLIKEAKNLTALKAGGTCDSFVKGYLLPSKSKSSSKKKTPVVKKTKSPNYNHTFVYNNLSLDELKDMCLELTVWDRETLSSNDFLGGVRLSLGAVTVKEGKEEWMADSTGEEILLWKKMMQYPDSWAEGTLPLRSSMGKGK", "length": 689 }, "evidence": [ { "id": "A0A3Q1LN74", "url": "https://omabrowser.org/oma/group/A0A3Q1LN74/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S1M2-1", "protein_name": "Synaptotagmin-like protein 4", "gene_name": "SYTL4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEILDLSFLSEVERDLILNVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQESLGRLTPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQKVNRFAYRTGSEIIRMSLRRKPAVNKRETVGQSLLHQSQLGDVWPGRKIIQEQQKEPSVPFDVPKLKSGKSALEAESESLDSYTADSDSMSRRDSLDKSGLFPEWKKMSAPKFQVEMETQPGGQNVVSIDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVGHESGSLGDRSKSVPGLSVDMEEEEEEEDIDHLVKLHRQKLARSSMRSGSSMSTIGSMMSIYSEAGDFGNIFVTGKVTFSLKYEQQTQTLVIHVKECQQLAYADEAKKHSNPYVKTYLLPDKSRQGKRKTSIKRDTVNPLYDEILTYEIPESVLSQRTLKFSVWHHGRFGRNTFLGEAEVQMDSWMLDKKLDHCLPLHGKISAEASTGLPSHKGELVVSLKYIPASKLPVGSDRKKSKVGEGGELQVWIKEAKNLMAAKSGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRASMAKQKLGL", "length": 671 }, "evidence": [ { "id": "A0A3Q1LN74", "url": "https://omabrowser.org/oma/group/A0A3Q1LN74/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VHQ7-1", "protein_name": "Synaptotagmin-like protein 4", "gene_name": "Sytl4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEILDLSFLSEMERDLILSVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQEGLGRLISKSNTCVGCNHLVCRECRVLESNGSWRCKVCSKEIELKKATGDWFYDQKVNRFAYRTGSDIIRMSLRRKPAVNKRETVGQSLLQQTQMGDIWPGRRIIQEQQKEQSVLFEVPKLKSGKSALEAESESLDSYTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKEIAPGNQNAVCGDEGDMIFKKNTRKVLRPSEYTKSVIDLRPEDVAQESGILGDRSKSVPGLSVDMEDEEEEEEDIDHLVKLHRQKLARGSMQSGSSMSTIGSMMSLYSEAGDFGNVSVTGKIAFSLKFEQKTQTLVIHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGRFGRNTFLGEAEVHMDSWKLDKKLDHCLPLHGKISTESSPGLPAHKGELVVSLKYIPASKLPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKSGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISSGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMVKQKLGV", "length": 672 }, "evidence": [ { "id": "A0A3Q1LN74", "url": "https://omabrowser.org/oma/group/A0A3Q1LN74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96C24-1", "protein_name": "Synaptotagmin-like protein 4", "gene_name": "SYTL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKLGL", "length": 671 }, "evidence": [ { "id": "A0A3Q1LN74", "url": "https://omabrowser.org/oma/group/A0A3Q1LN74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0Q1-1", "protein_name": "Synaptotagmin-like protein 4", "gene_name": "Sytl4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEILDLSFLSEMERDLILGVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQEGLGRLIPKSSTCVGCNHLVCRECRVLESNGSWRCKVCSKEIELKKATGDWFYDQKVNRFDYRTGSEIIRMSLRQKPAVNKRETAGQSLLQQTQMGDIWPGRRIIQEQQQREQSVLFEVPKTRSGKSALEAESESLDSYTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKEIPPGNQNAVCGDEGDMVFKKNTKKVLRPSEYTKSVIDLRPEDVAQESGILGDRSKSVPGLSVDMEEEEEEEEDIDHLVKLHRQKLARGSMQSGSSMSTLGSIMSIYSEAGDFGNISVTGKIAFSLKFEQKTQTLVIHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGRFGRNTFLGEAEVHMDSWKLDKKLDHCLPLHGKISTESSPGLPAHKGELVVSLKYIPASKLPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKSGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLSPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMVKQKLGV", "length": 673 }, "evidence": [ { "id": "A0A3Q1LN74", "url": "https://omabrowser.org/oma/group/A0A3Q1LN74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 435, "end_pos": 557, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN74" }, { "id": "PS50916", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RabBD", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 122, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 658, "end_pos": 660 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DW2-1", "uniprot_ac": "Q08DW2", "uniprot_id": "KPRA_BOVIN", "mass": { "chemical_mass": 39424.0, "monoisotopic_mass": 39424.0 }, "refseq": { "ac": "NP_001070325", "name": "phosphoribosyl pyrophosphate synthase-associated protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070325" }, "gene_names": [ { "name": "PRPSAP1", "type": "recommended", "evidence": [ { "id": "Q08DW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ] }, { "name": "PRPSAP1", "type": "synonym", "evidence": [ { "id": "NP_001070325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070325" } ] } ], "protein_names": [ { "name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "type": "recommended", "evidence": [ { "id": "Q08DW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DW2/entry#names_and_taxonomy" } ] }, { "name": "PRPP synthase-associated protein 1", "type": "synonym", "evidence": [ { "id": "NP_001070325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070325" }, { "id": "Q08DW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DW2/entry#names_and_taxonomy" } ] }, { "name": "PRPP synthetase-associated protein 1", "type": "synonym", "evidence": [ { "id": "NP_001070325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070325" } ] }, { "name": "phosphoribosyl pyrophosphate synthase-associated protein 1", "type": "synonym", "evidence": [ { "id": "NP_001070325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070325" } ] } ], "function": [ { "annotation": "Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2#function" }, { "database": "UniProtKB", "id": "A0AAF6ZDQ7", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZDQ7#function" }, { "database": "UniProtKB", "id": "ARBA00037514", "url": "https://www.uniprot.org/uniprotkb/ARBA00037514#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRPSAP1", "url": "https://www.uniprot.org/uniprotkb/Q08DW2", "locus": { "chromosome": "19", "start_pos": 55413082, "end_pos": 55387190, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030172", "url": "https://www.ensembl.org/id/ENSBTAG00000030172" } ] } } ], "crossref": [ { "id": "Q08DW2", "url": "https://alphafold.ebi.ac.uk/entry/Q08DW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030172", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "789409", "url": "https://www.ncbi.nlm.nih.gov/gene/789409", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789409", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIIACPG", "url": "https://omabrowser.org/oma/group/GIIACPG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NLT3", "url": "https://www.orthodb.org/?gene=A0A3Q1NLT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q08DW2", "url": "https://www.orthodb.org/?gene=Q08DW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10210:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10210:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070325", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070325", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLT3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZDQ7", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZDQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZDQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZDQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DW2-1", "url": "https://www.uniprot.org/uniprotkb/Q08DW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIQESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCAEMDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYRIYVMATHGILSAEAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356, "header": "sp|Q08DW2-1|KPRA_BOVIN Isoform 1 of Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Bos taurus OX=9913 GN=PRPSAP1 PE=2 SV=1 CANONICAL=Q08DW2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NLT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLT3/entry", "sequence": { "sequence": "MPRKLLLLPPLSVSSAFRAPRACPAARPAMNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIQESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEVRSTSKYPLVLKRDPMAQSYAERLRLGLAVIHGEAQCAEMDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYRIYVMATHGILSAEAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 382, "header": "tr|A0A3Q1NLT3-1|KPRA_BOVIN Computationally mapped isoform of Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Bos taurus OX=9913 GN=PRPSAP1 PE=2 SV=2 CANONICAL=Q08DW2-1" }, "locus": { "chromosome": "19", "start_pos": 55412498, "end_pos": 55387424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072671.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072671.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073412.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073412.2" } ] } }, { "isoform_ac": "A0AAF6ZDQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZDQ7/entry", "sequence": { "sequence": "MPRKLLLLPPLSVSSAFRAPRACPAARPAMNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIQESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCAEMDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYRIYVMATHGILSAEAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 385, "header": "tr|A0AAF6ZDQ7-1|KPRA_BOVIN Computationally mapped isoform of Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Bos taurus OX=9913 GN=PRPSAP1 PE=2 SV=1 CANONICAL=Q08DW2-1" }, "locus": { "chromosome": "19", "start_pos": 55412498, "end_pos": 55387424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042563.5", "url": "https://www.ensembl.org/id/ENSBTAT00000042563.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040198.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040198.3" } ] } }, { "isoform_ac": "Q08DW2-1", "url": "https://www.uniprot.org/uniprotkb/Q08DW2/entry#Q08DW2-1", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIQESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCAEMDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYRIYVMATHGILSAEAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356, "header": "sp|Q08DW2-1|KPRA_BOVIN Isoform 1 of Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Bos taurus OX=9913 GN=PRPSAP1 PE=2 SV=1 CANONICAL=Q08DW2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 177, "end_pos": 177, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "site_lbl": "Ser177" }, { "start_pos": 215, "end_pos": 215, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "site_lbl": "Ser215" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:789409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789409", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AKA5-1", "protein_name": "Phosphoribosyl pyrophosphate synthetase associated protein 1", "gene_name": "PRPSAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNAARSGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTSCARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLIQYIQEEIPDYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTEQDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIFVMATHGLLSADAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "Q08DW2", "url": "https://omabrowser.org/oma/group/Q08DW2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RWP0-1", "protein_name": "Phosphoribosyl pyrophosphate synthetase associated protein 1", "gene_name": "PRPSAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKKLLLLPPLSVSSAFRAPRACPASRPAMNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCAELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 385 }, "evidence": [ { "id": "Q08DW2", "url": "https://omabrowser.org/oma/group/Q08DW2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14558-1", "protein_name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "gene_name": "PRPSAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "Q08DW2", "url": "https://omabrowser.org/oma/group/Q08DW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54QU9-1", "protein_name": "Ribose-phosphate pyrophosphokinase C", "gene_name": "prsC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKTMESVRLISGSAHPQFAELLSKGMNIELSKCESKHFLNGETSVILGESVRSASVYIIQPTCSPNVNDNIMELLVLVDAVRRASSKHITAVIPFFGYGKQNKKEKSREPITGKLIANLIETSGVDRVISMDLEASQIQGFFNIPVDNLYAEPLIVKYIEKHYKHLGEKVVISPAVDGVKRAKLVSDKLNCDLAILDRQTKGDKEDMILVGDVSGKVAIIIGSIADTCETLALSAKILKSKGATNVFALVSHGELSGNAIETLNNSELEELVITNSIPQTEKSKQCPKLKIINVTPMFCEALKRIIHGESITAASSKFVIL", "length": 321 }, "evidence": [ { "id": "Q08DW2", "url": "https://omabrowser.org/oma/group/Q08DW2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q63468-1", "protein_name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "gene_name": "Prpsap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "Q08DW2", "url": "https://omabrowser.org/oma/group/Q08DW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D0M1-1", "protein_name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "gene_name": "Prpsap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "Q08DW2", "url": "https://omabrowser.org/oma/group/Q08DW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "5-phosphoribose 1-diphosphate biosynthetic process", "id": "GO:0006015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006015", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "pmid": "" }, { "name": "purine nucleotide biosynthetic process", "id": "GO:0006164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006164", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "pmid": "" }, { "name": "nucleotide biosynthetic process", "id": "GO:0009165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009165", "evidence": [ { "database": "UniProtKB", "id": "Q08DW2", "url": "https://www.uniprot.org/uniprotkb/Q08DW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DW2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 356, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DW2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DW2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 177, 215 ], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 351, "end_pos": 353 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "H7BWW1-1", "uniprot_ac": "H7BWW1", "uniprot_id": "H7BWW1_BOVIN", "mass": { "chemical_mass": 45532.0, "monoisotopic_mass": 45532.0 }, "refseq": { "ac": "XP_002689483", "name": "mitochondrial outer membrane protein SLC25A46 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689483" }, "gene_names": [ { "name": "SLC25A46", "type": "recommended", "evidence": [ { "id": "H7BWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ] }, { "name": "SLC25A46", "type": "synonym", "evidence": [ { "id": "XP_002689483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689483" } ] } ], "protein_names": [ { "name": "Mitochondrial outer membrane protein SLC25A46", "type": "recommended", "evidence": [ { "id": "H7BWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H7BWW1/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 25 member 46", "type": "synonym", "evidence": [ { "id": "H7BWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H7BWW1/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial outer membrane protein SLC25A46 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_002689483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689483" } ] } ], "function": [ { "annotation": "Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization. May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane. Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RV28", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV28#function" }, { "database": "UniProtKB", "id": "ARBA00056614", "url": "https://www.uniprot.org/uniprotkb/ARBA00056614#function" }, { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1#function" }, { "database": "UniProtKB", "id": "A0AAA9SRY9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRY9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC25A46", "url": "https://www.uniprot.org/uniprotkb/H7BWW1", "locus": { "chromosome": "7", "start_pos": 109761489, "end_pos": 109737357, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009667", "url": "https://www.ensembl.org/id/ENSBTAG00000009667" } ] } } ], "crossref": [ { "id": "H7BWW1", "url": "https://alphafold.ebi.ac.uk/entry/H7BWW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009667", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009667", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "531725", "url": "https://www.ncbi.nlm.nih.gov/gene/531725", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531725", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531725", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "H7BWW1", "url": "https://www.orthodb.org/?gene=H7BWW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21252:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21252:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002689483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689483", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RV28", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV28-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRY9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRY9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H7BWW1-1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHPRRPDGFDGLGYRGGARDEPGFGGAFPARSFSSASDLSRWVTSPPDIPGSRNLHWAEESPPRGAPAPCTPPEGPAEGPCPGGSGRSGGEGLGGGEQLNRFAGFGIGLASLFTENVLAHPCIVLRRQCQVNYHARHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGITLGAEGIISEFTPLPREISHKWNPKQIGEHLLLKSLTYIVAMPFYSASLIETVQSEIIRDGAGILECVKEGIGRAIGLGVPHSKRLLPLLSLVFPTVLHGVLHYVISSVVQKVVLLILKRKAYDGHLAEGASPVQSMLDAYFPELIANFAASLCSDVTLYPLETVLHRLHVQGTRTIIDNTDLGYEVLPINTQYEGVRDCVNTIRQEEGALGFYKGFGAVVVQYTLHAAVLQITKIIYSTLLQNSA", "length": 420, "header": "tr|H7BWW1-1|H7BWW1_BOVIN Isoform 1 of Mitochondrial outer membrane protein SLC25A46 OS=Bos taurus OX=9913 GN=SLC25A46 PE=3 SV=3 CANONICAL=H7BWW1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RV28-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV28/entry", "sequence": { "sequence": "MPFYSASLIETVQSEIIRDGAGILECVKEGIGRAIGLGVPHSKRLLPLLSLVFPTVLHGVLHYVISSVVQKVVLLILKRKAYDGHLAEGASPVQSMLDAYFPELIANFAASLCSDVTLYPLETVLHRLHVQGTRTIIDNTDLGYEVLPINTQYEGVRDCVNTIRQEEGALGFYKGFGAVVVQYTLHAAVLQITKIIYSTLLQNSA", "length": 205, "header": "tr|A0AAA9RV28-1|H7BWW1_BOVIN Computationally mapped isoform of Mitochondrial outer membrane protein SLC25A46 OS=Bos taurus OX=9913 GN=SLC25A46 PE=3 SV=2 CANONICAL=H7BWW1-1" }, "locus": { "chromosome": "7", "start_pos": 109760485, "end_pos": 109756016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100687.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100687.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077134.2", "url": "https://www.ensembl.org/id/ENSBTAP00000077134.2" } ] } }, { "isoform_ac": "A0AAA9SRY9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRY9/entry", "sequence": { "sequence": "MHPRRPDGFDGLGYRGGARDEPGFGGAFPARSFSSASDLSRWVTSPPDIPGSRNLHWAEESPPRGAPAPCTPPEGPAEGPCPGGSGRSGGEGLGGGEQLNRFAGFGIGLASSVAQSYPALCDPMNRSTPGLPVHYQLPEFTQTHVHRVNDAIQPSHPLSSPSPLAHNPSQHQSLFHLFTENVLAHPCIVLRRQCQVNYHARHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGITLGAEGIISEFTPLPREISHKWNPKQIGEHLLLKSLTYIVAMPFYSASLIETVQSEIIRDGAGILECVKEGIGRAIGLGVPHSKRLLPLLSLVFPTVLHGVLHYVISSVVQKVVLLILKRKAYDGHLAEGASPVQSMLDAYFPELIANFAASLCSDVTLYPLETVLHRLHVQGTRTIIDNTDLGYEVLPINTQYEGVRDCVNTIRQEEGALGFYKGFGAVVVQYTLHAAVLQITKIIYSTLLQNSA", "length": 485, "header": "tr|A0AAA9SRY9-1|H7BWW1_BOVIN Computationally mapped isoform of Mitochondrial outer membrane protein SLC25A46 OS=Bos taurus OX=9913 GN=SLC25A46 PE=3 SV=1 CANONICAL=H7BWW1-1" }, "locus": { "chromosome": "7", "start_pos": 109760485, "end_pos": 109738260, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102044.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102044.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086850.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086850.1" } ] } }, { "isoform_ac": "H7BWW1-1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1/entry", "sequence": { "sequence": "MHPRRPDGFDGLGYRGGARDEPGFGGAFPARSFSSASDLSRWVTSPPDIPGSRNLHWAEESPPRGAPAPCTPPEGPAEGPCPGGSGRSGGEGLGGGEQLNRFAGFGIGLASLFTENVLAHPCIVLRRQCQVNYHARHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGITLGAEGIISEFTPLPREISHKWNPKQIGEHLLLKSLTYIVAMPFYSASLIETVQSEIIRDGAGILECVKEGIGRAIGLGVPHSKRLLPLLSLVFPTVLHGVLHYVISSVVQKVVLLILKRKAYDGHLAEGASPVQSMLDAYFPELIANFAASLCSDVTLYPLETVLHRLHVQGTRTIIDNTDLGYEVLPINTQYEGVRDCVNTIRQEEGALGFYKGFGAVVVQYTLHAAVLQITKIIYSTLLQNSA", "length": 420, "header": "tr|H7BWW1-1|H7BWW1_BOVIN Isoform 1 of Mitochondrial outer membrane protein SLC25A46 OS=Bos taurus OX=9913 GN=SLC25A46 PE=3 SV=3 CANONICAL=H7BWW1-1" }, "locus": { "chromosome": "7", "start_pos": 109760485, "end_pos": 109738260, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042610.6", "url": "https://www.ensembl.org/id/ENSBTAT00000042610.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040246.5", "url": "https://www.ensembl.org/id/ENSBTAP00000040246.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531725", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531725", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "mitochondrial membrane fission", "id": "GO:0090149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090149", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "H7BWW1", "url": "https://www.uniprot.org/uniprotkb/H7BWW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317:SF81", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RWR6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWR6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYD1-1", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9C4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRZ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U046", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U046", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U046-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U046-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E580", "url": "https://www.uniprot.org/uniprotkb/G5E580", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E580-1", "url": "https://www.uniprot.org/uniprotkb/G5E580-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEM", "length": 2074, "header": "tr|G5E580-1|G5E580_BOVIN Isoform 1 of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=2 CANONICAL=G5E580-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWR6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWR6/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFESFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEI", "length": 2036, "header": "tr|A0AAA9RWR6-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2892002, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109755.2", "url": "https://www.ensembl.org/id/ENSBTAT00000109755.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075560.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075560.1" } ] } }, { "isoform_ac": "A0AAA9RYD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYD1/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDFFSFAVDRLTSVDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEI", "length": 2007, "header": "tr|A0AAA9RYD1-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2892002, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111145.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111145.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078576.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078576.1" } ] } }, { "isoform_ac": "A0AAA9S1T3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1T3/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEI", "length": 2042, "header": "tr|A0AAA9S1T3-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2892002, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123792.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123792.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076044.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076044.1" } ] } }, { "isoform_ac": "A0AAA9SFY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFY1/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDFFSFAVDRLTSVDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEI", "length": 2087, "header": "tr|A0AAA9SFY1-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2892002, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102800.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102800.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082547.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082547.1" } ] } }, { "isoform_ac": "A0AAA9SJD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJD9/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEI", "length": 2028, "header": "tr|A0AAA9SJD9-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2892002, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125687.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125687.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086385.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086385.1" } ] } }, { "isoform_ac": "A0AAA9T9C4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9C4/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFR", "length": 1988, "header": "tr|A0AAA9T9C4-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2891883, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111368.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111368.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093459.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093459.1" } ] } }, { "isoform_ac": "A0AAA9TRZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRZ1/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQ", "length": 1947, "header": "tr|A0AAA9TRZ1-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2886137, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117401.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117401.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099243.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099243.1" } ] } }, { "isoform_ac": "A0AAA9U046-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U046/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEI", "length": 2012, "header": "tr|A0AAA9U046-1|G5E580_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=1 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 2892002, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127460.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127460.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103247.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103247.1" } ] } }, { "isoform_ac": "G5E580-1", "url": "https://www.uniprot.org/uniprotkb/G5E580/entry", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEM", "length": 2074, "header": "tr|G5E580-1|G5E580_BOVIN Isoform 1 of Dedicator of cytokinesis 11 OS=Bos taurus OX=9913 GN=DOCK11 PE=3 SV=2 CANONICAL=G5E580-1" }, "locus": { "chromosome": "X", "start_pos": 3006904, "end_pos": 2680578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008444.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008444.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008444.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008444.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YI06-1", "protein_name": "Dedicator of cytokinesis 11", "gene_name": "DOCK11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSEVRKFTKRLSKPGTAAELRQSVSEAVRSSFALEKTKVVEPLDYENVILQRKVQIYSDPLRDLLIFPIEDVSLSVISRQRRTVQSTVPEDALKKAQSLFVKECIKTYSSDWHVVNYKYEEYSGDFRMLPCKSFRPDKIPSHVFEIDEDFEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMRVFKRRYFYLSQLTDGSYILNSYKDEKISKESKGCIFLDACNDVVQCPKMRRYAFELKTIDKYSHYLAAESEQEMEEWLVTLRKIIQSNTESSVQEKKDTVEAAQDDESSTQGKSENILESLERSMHPELMKYGRETDQLNKLSRNDGRQNLFSFDPEVQRLDFSGMEPDVKPFEEKSSRRFVVCCQDLSLNLLAQLSDQSEGGPTNVEPFFLSLALFDLKNNCKISADFHVDLNPPPVRDMLLDTSASKVEDVKGRSPGESLMHGIPESCLRYIKRGVFSVTDPHAEIFLVARVEKVLQGSITHCAEPYMKNSDPGKTAQKVHKVAKQVCSRLGLYRMPFGWAARPVFKDSQGTLDAEGKFSPLYKQDSGKLSNEDMLKLLAEYKKPEKTKLQIIPAQLNIVIKDIPLDFTNCVTASYIPIKPFEKSCENIAVEVEELVPEVAKYCYPFTVYKNHLYVYPLHLKYENQKVFAKARNIAVCIEFRDSDEADARPLKCIYGKPGGQLLTSNAYAAVLHHNQSPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKATSKKQDTVETQVGYAWVPLLKDGRIVTLERHLPVSSNLPPGYLGLGDTESRRQSSVDAKWVDGAKPLFKIRIHLDSTIYTQDMHLHKFFQYCQLVQAGVKEVPGELVKYLKCLHAMETQVMIQFLPVILMQLFRVLTNVTQEDEVAVNCTMVLLHIVSKCHEEGLDHYLRSFIKYVFRAEKPSVTQAKMTHEILVLSMATILKQSADFLAINKLLKYSWFFFEALAKSMAIYLLEENKIKLPRAQRFPDSYQHALHSLLLAIIPHVTIRYNEIPEESRNANFSLANFLKRCLTFMDRGFVFNLINDYISGFSPKDPKLLVEYKFEFLQTICNHEHYIPLNLPMTFSKPKLQRAQDVNLEYSLTDEYCRHHFLVGMLLRETSVALQDNYDIRCTAITVLKNLLIKHAFDNRYQHKNQQAKIVQLYLPLLGLLLENIQRVAGRDVLISCTAASSPASRDEFICNFASPSNRSSLIADKDSAALPNGHGMKREDSKGSLNSEGATGSPDQSENIRRSSTRSSVSHCSRLDQFEIRTLLMCYLYIVKMISEDTLLAYWNKFSPQELINVLVLLEVCLFHFRYVGKRNIARVHDAWVSKHGAADRKSQTMPALRSRAGGMQARLQHLGSLDTSFTLNHNAGTSEADIVHQALLEGNIATEVCLTVLDTISFFTQSFKTQLLSNDGHNPLMKKVFDIHLAFLKNGQSEAALKHVFASLRAFISKFPSAFFKGRVNMCAALCYEILKCCTSKVTSTRNEASALLYLLMRNNFEFTKRRTFLRTHLQIIIAVSQLIADVALSGGTRFQDSLLIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCTAFRKITPNIDEEGAMKEDGGMMDVHYSEEVLVELLEQCVDGLWKAERYETISEVSKLIIPIYEKRREFEKLTQLYRTLHGAYAKILEVMHTRKRLLGTFFRVAFYGQTFFEEEDGKEYIYKEPKLTGLSEISFRLLKLYGEKFGSETVKIIQDSNKVNIKDLDPRYAHIQVTYVKPYFEDKEISERKTEFERNHNINRFVFETPYTLSGKKHGSVEEQCKKRTILTTLNSFPYVKKRIPVNYEHQVNLKPIDVATDEIKDKTAELQKLCSASDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLSDSQSSKYPAKKVNELKEMFRKFIQACGIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQIYHEDPMHSPWMHDSLHVFCAISGTSSNGSYCSLRPTAEI", "length": 2068 }, "evidence": [ { "id": "G5E580", "url": "https://omabrowser.org/oma/group/G5E580/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AF47-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "Dock11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLIMLKKIIQINTDSLVQEKKDTVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFMVNCHDLTFNILGHIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGTSTQLSNDGNAKGFSPESLIHGIAESQLCYIKQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDVQGSLDLDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLSITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVITLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNGNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPSSASRDEFPCGFVSPTNRGSLASDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTSENTRQSSSRSSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKNQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQVNLKPIDVATDEIKDKTAELHKLCSSVDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYAEV", "length": 2073 }, "evidence": [ { "id": "G5E580", "url": "https://omabrowser.org/oma/group/G5E580/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0R034-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "dock11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEVRKFTKRLSKPGTAAELRQSVSEAVRTSIAVEQPKIIEPLDYENVVFQRKAQIHSDPQRDLLLWPADDVSEAHIDRHRRTINPSVPQNAENEAKSLFAKECIKMYNTNWHVINYNYEAYSGDFRMLPCKGMKTEKLPSQVFEVDEGEEDSSSLCSQRGGVMKQGWLQKANINSSLSVSMKVFKRRYFYLSQLPDGSYILNSYKDEKNYKESKGSIYLDSCIDVVPCPKMRRNGFELKMQERYSHYLAADSEAEMEDWVNTIKQALLSTMEDRRNGSETSEGSLDDDSSSQGKPESITESFGRSLHPELMKYARETDQLSKMSRNEGRQKIFSLDPEVQRLDFSGIEPDVKPFEERFGRRIMVSCHNLTFNLQGCVSEKNDGVLTNVEPFFISLALFDLSKGCKISADFHVDLNPPCVREMIQTGSAGTPTEAGEDENDPVKMNGHGLPLLQRVAESLLHFPTQGIFSVTNPHADIFLLARVEKVLQNGITHCADPYIKPSDISKTVQKVLKTAKQTCQRLGQYRMPFAWAAKQVFKDSQGTLDTDGKFSPLYRQDSSKISTEDLIKLLTDLKKPEKNKLQIIPGQINITVECVPPDLSNSVTSSYIPVKPFADQCDSVSVEVEEFVPEEARFNHPFTIYNNHLYIYPQQLKYDSQKAFDKARNIAVCVQFKDSDEEGSSPLKCIYGKPGDPLFTTSAFAAVLHHNQSPEFYDEIKIELPVHIHEKHHILFTFYHISCDLGTKTTSKKREGVETLVGYSWTPLLKDGRIKSSDLQLPVSANLLAGYLCDKSQDIKKVFPYIKWVDNAKPLFKVRAYVASTIYTQDLHLHNFFQHCQLMRSTSQGNPAELIKYLKCLHAVETQVVIKFLPTVLVQLFEVLSMASKEGQDVAVNSTRVIIHIVSQCHEEGLEHYLRSFLKYVFRINNATSENSVTTHEVLATAVTVILKQTADINTCNKLLKYSWFFFETMARSMAQYLMDGNRMKMPRAQRFPESFQQALQCLLLSIMPHITIRYVEIPEEARCVNFSLACFIKRCLTFMNRGFAFSLINDYMCGFSLKDPKVLTEMKFDFLMTVCNHEHYIPLNLPMAFGRTKLQRVQDFISYAAECFGVVDQSLEYSLTEDYCKNHFLVGLLLREVADGLQACPEIRQLAVAVLKNLMIKHAMDDRYNAFKNQQARICLLYLPLFELLYQNLSQMNSPRQMCRNGLGLMYRDDLSVDSRRSSTIVDKEPSGSVTQNGLSRRGESRGSMYGDPGTPDINELHRRGSTMSTVPAAGRLGQYEIRGLLLCYLHIVRTLSDDTLTAYWSKVNPQDIMNFLSLLEICIIQFRYVGRRNISRSQEPWVSKLFSPERKSQTMPVLRGRASLMQAKLQQFSTMDTSLTLNMAGGPTEAEINHQSLLEGNTSTEVCLTVLDVLSLFTQSFKNQLLDSDGHNALMTKIFDTYLTLLKVGQSETAIKHIFASLRAFIVKFQVPLFKGRVVLCGSLCYEVLKCCMSKLSVLRGEASALLYLLMRHNFDYTKRKSFLRVHLQIIIAVSQLIADVALTGSSRFQESLSIINNFANSDKIMKTTTFPSEVKGLTMRIRTVLMATAQMREHEKDPEMLLDLQYSLARSYASTPELRRTWLDSMARAHSKNGDFSEAAMCNVHVAALMAEYLHRKKLFPSGLAAFKRTTQNIDEEGAMKEDIGMQDVYYTEDVLVEQLEVCVESLWKAERFELITHIARLIIPVYEKRHEFEKLRRLYDTLQRAYAKILEVMQSGRRLLGTYFRVAFFGQGFFEEEDGKEYIYKEPKLTTLPEISHRLLKLYGEKFGSENVKIIQDSNKVNQKDLDSKFAYIQVTYVKPFFDEKEMAERKTDFEKCHNIQRFVFETPFTLTGKKQGGVEEQCKRRTVLTTANTFPYVKKRIEVVGEKHTELKPIDVAIDEMKEKSSELAKLCSNQEVNMITLQLKLQGCVSVQVNAGPMAYARAFLDESKSGQSNKKVKDLKEIFRQFVNACSMALDINERLIKEDQYEYHEGLKANFKSMVKELSEIIHEQIFQEDMMRSLLQNSLHVFRAISGTSTDLS", "length": 2067 }, "evidence": [ { "id": "G5E580", "url": "https://omabrowser.org/oma/group/G5E580/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LQ91-1", "protein_name": "Dedicator of cytokinesis 11", "gene_name": "Dock11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 2073 }, "evidence": [ { "id": "G5E580", "url": "https://omabrowser.org/oma/group/G5E580/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JSL3-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "DOCK11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV", "length": 2073 }, "evidence": [ { "id": "G5E580", "url": "https://omabrowser.org/oma/group/G5E580/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G5E580", "url": "https://www.uniprot.org/uniprotkb/G5E580" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "G5E580", "url": "https://www.uniprot.org/uniprotkb/G5E580" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "G5E580", "url": "https://www.uniprot.org/uniprotkb/G5E580" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "G5E580", "url": "https://www.uniprot.org/uniprotkb/G5E580" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1024, "end_pos": 1026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1358, "end_pos": 1360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1380, "end_pos": 1382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1968, "end_pos": 1970, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 881, "end_pos": 883, "annotation": "n_glycosylation_sequon" }, { "start_pos": 891, "end_pos": 893, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E580" }, { "id": "PS51650", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 DOCK-type", "eco_id": "ECO_0000259", "start_pos": 640, "end_pos": 818, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E580" }, { "id": "PS51651", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51651" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOCKER", "eco_id": "ECO_0000259", "start_pos": 1609, "end_pos": 2036, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E580" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 272, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1024, "end_pos": 1026 }, { "start_pos": 1358, "end_pos": 1360 }, { "start_pos": 1380, "end_pos": 1382 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 1968, "end_pos": 1970 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 617, "end_pos": 619 }, { "start_pos": 881, "end_pos": 883 }, { "start_pos": 891, "end_pos": 893 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"evidence": [ { "id": "A0A140T857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T857/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome c oxidase subunit VIIa-liver/heart", "type": "synonym", "evidence": [ { "id": "A0A140T857", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T857/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T857", "url": "https://www.uniprot.org/uniprotkb/A0A140T857" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "COX7A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T857", "locus": { "chromosome": "9", "start_pos": 14833566, "end_pos": 14838697, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005096", 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"MGQTAGNLGWRLSLLLLFLLLARAGVWGFPRPPGRPPLSLQELQREFKVSLHLARKLLSEVRVQAHHFAESHLPGVNLDLLPLAEQLPNVSTTFQAWRGLSALSRIDLVMEWMETGVVLGMGPREFWTSSERMQLQATRLDLRDLQQHLRFQVLAAGFNLPEEHENEEEKGLLPGALGAPLQISAQVSWSRFLYTYRLLHSLELLLSRTVRDLLLLSRAGNSVQALGFPTPSSQP", "length": 235, "header": "tr|A0AAA9S3K3-1|A0A3Q1LK84_BOVIN Computationally mapped isoform of Interleukin-27 subunit alpha OS=Bos taurus OX=9913 GN=IL27 PE=3 SV=1 CANONICAL=A0A3Q1LK84-1" }, "locus": { "chromosome": "25", "start_pos": 26066562, "end_pos": 26061511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118903.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118903.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080517.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080517.1" } ] } }, { "isoform_ac": "F6PU87-1", "url": "https://www.uniprot.org/uniprotkb/F6PU87/entry", "sequence": { "sequence": "QRWNQSYKQRSRWEAQGLSLLLLFLLLARAGVWGFPRPPGRPPLSLQELQREFKVSLHLARKLLSEVRVQAHHFAESHLPGVNLDLLPLAEQLPNVSTTFQAWRGLSDPERLCFLSLTLRPFHTLLGGLGKQEFWTSSERMQLQATRLDLRDLQQHLRFQVLAAGFNLPEEHENEEEKGLLPGALGAPLQISAQVSWSRFLYTYRLLHSLELLLSRTVRDLLLLSRAGNSVQALGFPTPSSQP", "length": 243, "header": "tr|F6PU87-1|A0A3Q1LK84_BOVIN Computationally mapped isoform of Interleukin-27 subunit alpha OS=Bos taurus OX=9913 GN=IL27 PE=3 SV=3 CANONICAL=A0A3Q1LK84-1" }, "locus": { "chromosome": "25", "start_pos": 26065929, "end_pos": 26061511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023979.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023979.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023979.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023979.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9020956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9020956", "resource": "Reactome", "description": "Interleukin-27 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4I8-1", "protein_name": "Interleukin-27 subunit alpha", "gene_name": "IL27", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQMADDLGWRLSLLLLSMLLARAGVWGFPRPPGRPPLSLQELQREFKVSLHLARKLLSEVRVQARHFAESHLPGVNLDLLPLGEQLPNVSLNFQAWRGLSDPERLCFLSMTLRPFHTLLGGLGSQGFWTSSERMQLWAIRLDLRDLQQHLRFQVLAAGFNLPGQEEEENEAGKEMLPGAPGGPSKPAAQVSWPRLLYTYQLLRSLELVLSRAMRDFLLLSRAGNPAPALGFPTPSSPP", "length": 239 }, "evidence": [ { "id": "A0A3Q1LK84", "url": "https://omabrowser.org/oma/group/A0A3Q1LK84/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LSP0-1", "protein_name": "Interleukin-27 subunit alpha", "gene_name": "Il27", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGQVTGGLGWRLSLLLLPLLLVQAGAWGFPTGPLSLQELRREFTVSLYLARKLLSEAQGYVHSFAESRLPGVNLDLLPLGHHLPNVSLTFQAWRHLSDPERLCFLSTTLRPFPALLEGLGNQGTWTSSERGQLWAMRLDLRDLHRHFRFQVLAAGFNCSAEEEEEEEEEEEEEEGKELLLGALDGPKQVSSQVSWPQLLYTYQLLHSLELVLSRAVRDLLLLTMSPHPDPALGS", "length": 234 }, "evidence": [ { "id": "A0A3Q1LK84", "url": "https://omabrowser.org/oma/group/A0A3Q1LK84/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZPW3-1", "protein_name": "Interleukin-27 subunit alpha", "gene_name": "Il27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQVTGGLGWRLSLLLLPLLMVQTGSWGFPADPLSLQELRREFTVSLYLARKLLSEVQGYVHSFAESRLPGVNLDLLPVGHHLPNVSLTFQAWRHLSDSDRLCFLATTLRPFPALLGGLETQRTWTSSEREQLWAMRLDLRDLHRHLRFQVLAVGFSCSEEEKEEEEEDEEEEEGKELLLGALGGPNQVSSQVSWPQLLYAYQLLHSLELVLSRAVRDLLLLSLPRRPDSACDP", "length": 234 }, "evidence": [ { "id": "A0A3Q1LK84", "url": "https://omabrowser.org/oma/group/A0A3Q1LK84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K3I6-1", "protein_name": "Interleukin-27 subunit alpha", "gene_name": "Il27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQVTGDLGWRLSLLLLPLLLVQAGSWGFPTDPLSLQELRREFTVSLYLARKLLSEVQGYVHSFAESRLPGVNLDLLPLGYHLPNVSLTFQAWHHLSDSERLCFLATTLRPFPAMLGGLGTQGTWTSSEREQLWAMRLDLRDLHRHLRFQVLAAGFKCSKEEEDKEEEEEEEEEEKKLPLGALGGPNQVSSQVSWPQLLYTYQLLHSLELVLSRAVRDLLLLSLPRRPGSAWDS", "length": 234 }, "evidence": [ { "id": "A0A3Q1LK84", "url": "https://omabrowser.org/oma/group/A0A3Q1LK84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NEV9-1", "protein_name": "Interleukin-27 subunit alpha", "gene_name": "IL27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQTAGDLGWRLSLLLLPLLLVQAGVWGFPRPPGRPQLSLQELRREFTVSLHLARKLLSEVRGQAHRFAESHLPGVNLYLLPLGEQLPDVSLTFQAWRRLSDPERLCFISTTLQPFHALLGGLGTQGRWTNMERMQLWAMRLDLRDLQRHLRFQVLAAGFNLPEEEEEEEEEEEEERKGLLPGALGSALQGPAQVSWPQLLSTYRLLHSLELVLSRAVRELLLLSKAGHSVWPLGFPTLSPQP", "length": 243 }, "evidence": [ { "id": "A0A3Q1LK84", "url": "https://omabrowser.org/oma/group/A0A3Q1LK84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "interleukin-27 receptor binding", "id": "GO:0045523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045523", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor receptor binding", "id": "GO:0005127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005127", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "regulation of T cell proliferation", "id": "GO:0042129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042129", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor-mediated signaling pathway", "id": "GO:0070120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070120", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "regulation of T-helper 1 cell differentiation", "id": "GO:0045625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045625", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A140T8B4-1", "uniprot_ac": "A0A140T8B4", "uniprot_id": "A0A140T8B4_BOVIN", "mass": { "chemical_mass": 38960.0, "monoisotopic_mass": 38960.0 }, "refseq": {}, "gene_names": [ { "name": "ZAR1L", "type": "recommended", "evidence": [ { "id": "A0A140T8B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ] } ], "protein_names": [ { "name": "Zygote arrest 1 like", "type": "synonym", "evidence": [ { "id": "A0A140T8B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation. Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs. Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TJ89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ89#function" }, { "database": "UniProtKB", "id": "ARBA00049576", "url": "https://www.uniprot.org/uniprotkb/ARBA00049576#function" }, { "database": "UniProtKB", "id": "A0AAA9SDG8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDG8#function" }, { "database": "UniProtKB", "id": "A0AAA9SI54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI54#function" }, { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZAR1L", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4", "locus": { "chromosome": "12", "start_pos": 28692389, "end_pos": 28670476, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000026384", "url": "https://www.ensembl.org/id/ENSBTAG00000026384" } ] } } ], "crossref": [ { "id": "A0A140T8B4", "url": "https://alphafold.ebi.ac.uk/entry/A0A140T8B4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000026384", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026384", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616037", "url": "https://www.ncbi.nlm.nih.gov/gene/616037", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616037", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616037", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KFSCGNI", "url": "https://omabrowser.org/oma/group/KFSCGNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T8B4", "url": "https://www.orthodb.org/?gene=A0A140T8B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31054", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31054", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31054:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31054:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001120912", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDG8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDG8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SI54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SI54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ89-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVEHKTRPETNCLGILRCAWAPGGRMERIFCVPYSLYPGYGNMLRLGQSGLSEPRQPHWRQTNVPPTFLARPRLLMPSNASDCCVDPYKRAQLMAVFSHMNPGLSLRLRKANTKDVGVQVSLRVGKSVQCSLGPRTLDSLSPWASAGHRAPASAWGVSSSVPGHWGEVRLREELSDPPEAGQPPPPLPPPSPPPRSEEDPPEELQPREELVEEDSSSPRERKSKPAPVDSSQPLGRPNFQFLEPKYGYFHCKDCKTRWESAYVWCISGTNKVYFKQLCCKCQKSFNPYRVEAIQCQTCSKSRCSCPQKKRHINLRRPHRQELCGRCKDKRFSCGSIYSFKYIM", "length": 344, "header": "tr|A0A140T8B4-1|A0A140T8B4_BOVIN Isoform 1 of Zygote arrest 1 like OS=Bos taurus OX=9913 GN=ZAR1L PE=3 SV=1 CANONICAL=A0A140T8B4-1" }, "isoforms": [ { "isoform_ac": "A0A140T8B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4/entry", "sequence": { "sequence": "MKVEHKTRPETNCLGILRCAWAPGGRMERIFCVPYSLYPGYGNMLRLGQSGLSEPRQPHWRQTNVPPTFLARPRLLMPSNASDCCVDPYKRAQLMAVFSHMNPGLSLRLRKANTKDVGVQVSLRVGKSVQCSLGPRTLDSLSPWASAGHRAPASAWGVSSSVPGHWGEVRLREELSDPPEAGQPPPPLPPPSPPPRSEEDPPEELQPREELVEEDSSSPRERKSKPAPVDSSQPLGRPNFQFLEPKYGYFHCKDCKTRWESAYVWCISGTNKVYFKQLCCKCQKSFNPYRVEAIQCQTCSKSRCSCPQKKRHINLRRPHRQELCGRCKDKRFSCGSIYSFKYIM", "length": 344, "header": "tr|A0A140T8B4-1|A0A140T8B4_BOVIN Isoform 1 of Zygote arrest 1 like OS=Bos taurus OX=9913 GN=ZAR1L PE=3 SV=1 CANONICAL=A0A140T8B4-1" }, "locus": { "chromosome": "12", "start_pos": 28679803, "end_pos": 28670825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037484.5", "url": "https://www.ensembl.org/id/ENSBTAT00000037484.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037315.4", "url": "https://www.ensembl.org/id/ENSBTAP00000037315.4" } ] } }, { "isoform_ac": "A0AAA9SDG8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDG8/entry", "sequence": { "sequence": "MKVEHKTRPETNCLGILRCAWAPGGRMERIFCVPYSLYPGYGNMLRLGQSGLSEPRQPHWRQTNVPPTFLARPRLLMPSNASDCCVDPYKRAQLMAVFSHMNPGLSLRLRKANTKDVGVQVSLRVGKSVQCSLGPRTLDSLSPWASAGHRAPASAWGVSSSVPGHWGEVRLREELSDPPEAGQPPPPLPPPSPPPRSEEDPPEELQPREELVEEDSSSPRERKSKPAPVDSSQPLGRPNFQVYFKQLCCKCQKSFNPYRVEAIQCQTCSKSRCSCPQKKRHINLRRPHRQELCGRCKDKRFSCGSIYSFKYIM", "length": 313, "header": "tr|A0AAA9SDG8-1|A0A140T8B4_BOVIN Computationally mapped isoform of Zygote arrest 1 like OS=Bos taurus OX=9913 GN=ZAR1L PE=3 SV=1 CANONICAL=A0A140T8B4-1" }, "locus": { "chromosome": "12", "start_pos": 28679803, "end_pos": 28670825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113433.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113433.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084182.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084182.1" } ] } }, { "isoform_ac": "A0AAA9SI54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI54/entry", "sequence": { "sequence": "MKVEHKTRPETNCLGILRCAWAPGGRMERIFCVPYSLYPGYGNMLRLGQSGLSEPRQPHWRQTNVPPTFLARPRLLMPSNASDCCVDPYKRAQLMAVFSHMNPGLSLRLRKANTKDVGVQVSLRVGKSVQCSLGPRTLDSLSPWASAGHRAPASAWGVSSSVPGHWGEVRLREELSDPPEAGQPPPPLPPPSPPPRSEEDPPEELQPREELVEEDSSSPRERKSKPAPVDSSQPLGRPNFQFLEPKYGYFHCKDCKTRWESAYVWCISGTNKVYFKQLCCKCQKSFNPYRVEAIQCQTSLVAQMVKCLPTMGKTQVQSLGWEYPLEKEMATHCSILAWEIPWMEEPGRLQSMGSQRVGHD", "length": 360, "header": "tr|A0AAA9SI54-1|A0A140T8B4_BOVIN Computationally mapped isoform of Zygote arrest 1 like OS=Bos taurus OX=9913 GN=ZAR1L PE=3 SV=1 CANONICAL=A0A140T8B4-1" }, "locus": { "chromosome": "12", "start_pos": 28676563, "end_pos": 28670825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099537.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099537.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085915.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085915.1" } ] } }, { "isoform_ac": "A0AAA9TJ89-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ89/entry", "sequence": { "sequence": "MKVEHKTRPETNCLGILRCAWAPGGRMERIFCVPYSLYPGYGNMLRLGQSGLSEPRQPHWRQTNVPPTFLARPRLLMPSNASDCCVDPYKRAQLMAVFSHMNPGLSLRLRKANTKDVGVQVSLRVGKSVQCSLGPRTLDSLSPWASAGHRAPASAWGVSSSVPGHWGEVRLREELSDPPEAGQPPPPLPPPSPPPRSEEDPPEELQPREELVEEDSSSPRERKSKPAPVDSSQPLGRPNFQFLEPKYGYFHCKDCKTRWESAYVWCISGTNKVYFKQLCCKCQKSFNPYRVEAIQCQPKMEKLYTVSKNKTGSWLWLIS", "length": 319, "header": "tr|A0AAA9TJ89-1|A0A140T8B4_BOVIN Computationally mapped isoform of Zygote arrest 1 like OS=Bos taurus OX=9913 GN=ZAR1L PE=3 SV=1 CANONICAL=A0A140T8B4-1" }, "locus": { "chromosome": "12", "start_pos": 28692323, "end_pos": 28670825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116415.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116415.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096982.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096982.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616037", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616037", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJA5-1", "protein_name": "Zygote arrest 1-like", "gene_name": "Zar1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRFLRVPRGYGITQPLTYPGPGSHSQQQNWPQNMGAPVFLARPRVPANVSQPCMDPYNRAQLQVVPTQMNPNVSLCLHKANTKDVGIQVSLQVDKSVQCSLGSQTLHSSSLSDRTSSRKPTEAWRAGQRGLIQLPQGGEDKKSPELTGPTEANQLVPPTRSQDDDKQDTLSQLKESGEAYAPSPQDRKSKQFLEPKYGYFHCKDCKTRWESAYVWCITGTNKVYFKQLCSKCQKSFNPYRVEAIQCQTCLSSCCSCSQKKRHINLRRPHRQELCGHCKDKKFPCSVFYSFK", "length": 292 }, "evidence": [ { "id": "A0A140T8B4", "url": "https://omabrowser.org/oma/group/A0A140T8B4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287AST9-1", "protein_name": "Zygote arrest 1 like", "gene_name": "ZAR1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLNQLVWRKRGRLKMEGKIRTQTNCPGILRCAWAPGGRMERFVRVPYSLYPGYGNTLPLGHPGLAEHKQPDWRQNNGPPAFLARPGLLVPSNAADYCVDPRRRAQLKAILSQMNPSLSLRLCKANTKEVGVQVSPPVDKSVQCSLGPRTLHSRSPWSGPGQQAPGSAWGVSSSVMDRKGVGLLRKDGEHEERKALSGLAEPGQQPPPPPPPTPSSEEDQREECHQHDASGEEDASSPEERQDKQAQGGGGAPFRPKPTFQFLEPKYGYFHCKDCKTRWESAYVWCISGTNKVYFKQLCCKCQKSFNPYRVEAIQCQTCSKSRCSCPQKKRHIDLRKPHRQELCGRCKDKRFSCGNIYNFKYIARQGVHLVQDT", "length": 374 }, "evidence": [ { "id": "A0A140T8B4", "url": "https://omabrowser.org/oma/group/A0A140T8B4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XTC9-1", "protein_name": "Zygote arrest 1-like", "gene_name": "ZAR1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESFVFPPFGSFQGFRGGLTPNRSGELTPKQPSWKQSKSSGLSPFPVGPPTPLSADYLDSCRRAQLKALLSQVSPGLTPRLRRANTKEVGVQVNPRADAAVQCSLGPRTLPASRPLTPAARARGRLALYSPLLNPRLFTLPEAAAHQEDEAAAAAAPEEHKAEGRSDEQRDGPAEAAAPTEAPREQGVAPGRRAAFQFLEQKYGYFHCKDCKTRWESAYVWCISGSNKVYFKQLCRKCQKGFNPYRVEAIQCQTCFKTRCSCPQKKRHIDLTRPHRQELCGRCKGKRLSCDNTYSFKYIV", "length": 300 }, "evidence": [ { "id": "A0A140T8B4", "url": "https://omabrowser.org/oma/group/A0A140T8B4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6NP61-1", "protein_name": "Protein ZAR1-like", "gene_name": "ZAR1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERFVRVPYGLYQGYGSTVPLGQPGLSGHKQPDWRQNMGPPTFLARPGLLVPANAPDYCIDPYKRAQLKAILSQMNPSLSPRLCKPNTKEVGVQVSPRVDKAVQCSLGPRTLSSCSPWDGRDPQEPLPACGVTSPATGRRGLIRLRRDGDEAESKALPGPAEASQPQPPSRRSGADRQEEPGQLEESGEKDAPCPQETKSKQVPGDAASEPLRRPNFQFLEPKYGYFHCKDCKTRWESAYVWCISGTNKVYFKQLCCKCQKSFNPYRVEAIQCQTCSKSHCSCPQKKRHIDLRRPHRQELCGRCKDKRFSCGNIYSFKYVM", "length": 321 }, "evidence": [ { "id": "A0A140T8B4", "url": "https://omabrowser.org/oma/group/A0A140T8B4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "C3VD30-1", "protein_name": "Protein ZAR1-like", "gene_name": "Zar1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERLFCVPCGYGTTDPLTYPGPWRHCQQQNWPQNMGAPIFLARLRVPANVSQSCMNPYNRAQLQAVSTQMDPNLSLWLRSVHTTEVGVQVSLRVDKSVQCSQGSQTLHSSSLSDRTSSRKPTEAWEVGRRALIRRPQDGEDEESQEELTGPTEASQLLLPTWSRDREEQFPRLKELGEEYAHSPQDRKGKQFLELKYGYFHCKDCKRRWESAYVWCISGTNKVYFKQLCNKCQKSFNPYRVEEIQCQTCLRVCCSCSPKKRHIDVRRPHRQELCGHCKDKKFSCSVFFSLK", "length": 291 }, "evidence": [ { "id": "A0A140T8B4", "url": "https://omabrowser.org/oma/group/A0A140T8B4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" }, { "name": "oocyte maturation", "id": "GO:0001556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001556", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8B4", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A140T8B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8B4" }, { "id": "SM01328", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01328" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "3CxxC-type", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 330, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5R6-1", "uniprot_ac": "G5E5R6", "uniprot_id": "G5E5R6_BOVIN", "mass": { "chemical_mass": 40819.0, "monoisotopic_mass": 40819.0 }, "refseq": {}, "gene_names": [ { "name": "PARD6B", "type": "recommended", "evidence": [ { "id": "G5E5R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ] } ], "protein_names": [ { "name": "Par-6 family cell polarity regulator beta", "type": "synonym", "evidence": [ { "id": "G5E5R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5R6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PARD6B", "url": "https://www.uniprot.org/uniprotkb/G5E5R6", "locus": { "chromosome": "13", "start_pos": 78722535, "end_pos": 78706562, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021601", "url": "https://www.ensembl.org/id/ENSBTAG00000021601" } ] } } ], "crossref": [ { "id": "G5E5R6", "url": "https://alphafold.ebi.ac.uk/entry/G5E5R6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021601", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021601", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06718", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06718", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PGYPQQI", "url": "https://omabrowser.org/oma/group/PGYPQQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LS90", "url": "https://www.orthodb.org/?gene=A0A3Q1LS90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E5R6", "url": "https://www.orthodb.org/?gene=G5E5R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14102:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14102:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-420029", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-420029", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LS90", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LS90-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFR8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCX8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5R6-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRGHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISLPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGASVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDTSLPSCAPPPEPSLEPGEDDSDDDEDIVIEDSGEPRQIPRAAPSAESLQSLTQVELSFESGQNGFIPANEVSLPPVASGAGTEFETRAPDQKLLEEDGTVITL", "length": 373, "header": "tr|G5E5R6-1|G5E5R6_BOVIN Isoform 1 of Par-6 family cell polarity regulator beta OS=Bos taurus OX=9913 GN=PARD6B PE=3 SV=1 CANONICAL=G5E5R6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LS90-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS90/entry", "sequence": { "sequence": "VRREDCCQHLDSRQDLFELTHSAGQSPFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISLPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGASVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDTSLPSCAPPPEPSLEPGEDDSDDDEDIVIEDSGEPRQIPRAAPSAESLQSLTQVELSFESGQNGFIPANEVSLPPVASGAGTEFETRAPDQKLLEEDGTVITL", "length": 378, "header": "tr|A0A3Q1LS90-1|A0A3Q1LS90_BOVIN Computationally mapped isoform of Par-6 family cell polarity regulator beta OS=Bos taurus OX=9913 GN=PARD6B PE=3 SV=2 CANONICAL=G5E5R6-1" }, "locus": { "chromosome": "13", "start_pos": 78721531, "end_pos": 78711336, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072490.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072490.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059888.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059888.2" } ] } }, { "isoform_ac": "A0AAA9SFR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFR8/entry", "sequence": { "sequence": "ARARAAAAARPEVRERARAGPAAESEAAARVPAAPPPSPPPPSRPPLRPGGRAPRPRPPRRQSDPRSRCVRSQPSGARRGDASRGRASAGACEEEPGPPPPPRPEPAGRALAPRAPEGRPGWRRPPRARPQDEPRPPARGGQRLPGHHGSEEQEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISLPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGASVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDTSLPSCAPPPEPSLEPGEDDSDDDEDIVIEDSGEPRQIPRAAPSAESLQSLTQVELSFESGQNGFIPANEVSLPPVASGAGTEFETRAPDQKLLEEDGTVITL", "length": 430, "header": "tr|A0AAA9SFR8-1|G5E5R6_BOVIN Computationally mapped isoform of Par-6 family cell polarity regulator beta OS=Bos taurus OX=9913 GN=PARD6B PE=3 SV=1 CANONICAL=G5E5R6-1" }, "locus": { "chromosome": "13", "start_pos": 78721531, "end_pos": 78706793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126589.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126589.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082720.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082720.1" } ] } }, { "isoform_ac": "A0AAA9TCX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCX8/entry", "sequence": { "sequence": "SHPSLAARDQSNGGRRAFRAGGPAPARREAGTDWLAPRAQVRASHWVGAERGPPKLRRRLQFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISLPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGASVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDTSLPSCAPPPEPSLEPGEDDSDDDEDIVIEDSGEPRQIPRAAPSAESLQSLTQVELSFESGQNGFIPANEVSLPPVASGAGTEFETRAPDQKLLEEDGTVITL", "length": 412, "header": "tr|A0AAA9TCX8-1|G5E5R6_BOVIN Computationally mapped isoform of Par-6 family cell polarity regulator beta OS=Bos taurus OX=9913 GN=PARD6B PE=3 SV=1 CANONICAL=G5E5R6-1" }, "locus": { "chromosome": "13", "start_pos": 78721531, "end_pos": 78706606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129461.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129461.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095934.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095934.1" } ] } }, { "isoform_ac": "G5E5R6-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R6/entry", "sequence": { "sequence": "MNRGHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISLPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGASVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDTSLPSCAPPPEPSLEPGEDDSDDDEDIVIEDSGEPRQIPRAAPSAESLQSLTQVELSFESGQNGFIPANEVSLPPVASGAGTEFETRAPDQKLLEEDGTVITL", "length": 373, "header": "tr|G5E5R6-1|G5E5R6_BOVIN Isoform 1 of Par-6 family cell polarity regulator beta OS=Bos taurus OX=9913 GN=PARD6B PE=3 SV=1 CANONICAL=G5E5R6-1" }, "locus": { "chromosome": "13", "start_pos": 78721531, "end_pos": 78707187, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028786.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028786.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028786.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028786.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-420029", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-420029", "resource": "Reactome", "description": "Tight junction interactions" }, { "id": "R-BTA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A5GHK8-1", "protein_name": "Par-6 family cell polarity regulator beta", "gene_name": "PARD6B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVIRNSRTSGSSGQSTDNSLLGYPQQVEPSFEPEDEDSDDDDIIIEDSGVPQQIPKAVRNTESLESLTQIELSFESGQNGFIPSNEVSLAPVASGTNTEFETRAPDQKLLEEDGTIITL", "length": 372 }, "evidence": [ { "id": "G5E5R6", "url": "https://omabrowser.org/oma/group/G5E5R6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9BYG5-1", "protein_name": "Partitioning defective 6 homolog beta", "gene_name": "PARD6B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL", "length": 372 }, "evidence": [ { "id": "G5E5R6", "url": "https://omabrowser.org/oma/group/G5E5R6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JK83-1", "protein_name": "Partitioning defective 6 homolog beta", "gene_name": "Pard6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRGHRHGASSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIRKKNMLSNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSSQSTDNSLLGFPQQVEASFEPEDQDSDEDDIIIEDSGEPQQIPKATPAQSLESLTQIELSFESGQNGFSPPQDTSLVPVPGSLDTELESRAPDQKLLEEDGTIITL", "length": 371 }, "evidence": [ { "id": "G5E5R6", "url": "https://omabrowser.org/oma/group/G5E5R6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "regulation of cellular localization", "id": "GO:0060341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060341", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "G5E5R6", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5R6" }, { "id": "PS51745", "database": "PROSITE", "url": 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{ "id": "P56982-1", "url": "https://www.uniprot.org/uniprotkb/P56982-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLIGFGYAALVTFGSILGYKRRGGVLSLIAGLFVGFLAGYGAYRVSNDKRDVKLSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSLLMILRLVLLLL", "length": 99, "header": "sp|P56982-1|TM14A_BOVIN Isoform 1 of Transmembrane protein 14A OS=Bos taurus OX=9913 GN=TMEM14A PE=3 SV=1 CANONICAL=P56982-1" }, "isoforms": [ { "isoform_ac": "A0AAF6YNK1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YNK1/entry", "sequence": { "sequence": "MDLIGFGYAALVTFGSILGYKRRGGVLSLIAGLFVGFLAGYGAYRVSNDKRDVKLSLFTAFFLATIMGVRFKRSKKIMPAGLVAGLSEHFLSGQFSHIWEVQVQGS", "length": 106, "header": "tr|A0AAF6YNK1-1|TM14A_BOVIN Computationally mapped isoform of Transmembrane protein 14A OS=Bos taurus OX=9913 GN=TMEM14A PE=3 SV=1 CANONICAL=P56982-1" }, "locus": { "chromosome": "23", "start_pos": 25065823, "end_pos": 25060274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"gene": [ { "name": "MTG1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3", "locus": { "chromosome": "26", "start_pos": 25587819, "end_pos": 25599880, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020304", "url": "https://www.ensembl.org/id/ENSBTAG00000020304" } ] } } ], "crossref": [ { "id": "A0A140T8A3", "url": "https://alphafold.ebi.ac.uk/entry/A0A140T8A3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020304", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020304", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509768", "url": "https://www.ncbi.nlm.nih.gov/gene/509768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GVLWPKF", "url": "https://omabrowser.org/oma/group/GVLWPKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T8A3", "url": "https://www.orthodb.org/?gene=A0A140T8A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45782:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45782:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059737800", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJC3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJC3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYU9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLSPRSLCAAVRAAWRESFPLEGRDVARWFPGHMAKGLKKMQSSLRLVDCIIEVHDARIPLSGRNPLFQETLGLKPHLLVLNKMDLADLKEQQKIIQHLEREGIKHVVFTNCVKDENVKQVIPTVTELVGSSYRYHRGEHVEYCIMVIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSRIQVCERPLMFLLDTPGVLAPRIPSVETGLKLALCGTVLDHLVGEETLADFLLYTLNRHQLSGYVQHYGLGEACDDIASVLKRVAVKLRKTQKVKVLTGTGNVNVIQPDYPAAARDFLRAFRSGLLGPVMLDRDLLQGRSAEES", "length": 332, "header": "tr|A0A140T8A3-1|A0A140T8A3_BOVIN Isoform 1 of Mitochondrial GTPase 1 OS=Bos taurus OX=9913 GN=MTG1 PE=3 SV=1 CANONICAL=A0A140T8A3-1" }, "isoforms": [ { "isoform_ac": "A0A140T8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3/entry", "sequence": { "sequence": "MRLSPRSLCAAVRAAWRESFPLEGRDVARWFPGHMAKGLKKMQSSLRLVDCIIEVHDARIPLSGRNPLFQETLGLKPHLLVLNKMDLADLKEQQKIIQHLEREGIKHVVFTNCVKDENVKQVIPTVTELVGSSYRYHRGEHVEYCIMVIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSRIQVCERPLMFLLDTPGVLAPRIPSVETGLKLALCGTVLDHLVGEETLADFLLYTLNRHQLSGYVQHYGLGEACDDIASVLKRVAVKLRKTQKVKVLTGTGNVNVIQPDYPAAARDFLRAFRSGLLGPVMLDRDLLQGRSAEES", "length": 332, "header": "tr|A0A140T8A3-1|A0A140T8A3_BOVIN Isoform 1 of Mitochondrial GTPase 1 OS=Bos taurus OX=9913 GN=MTG1 PE=3 SV=1 CANONICAL=A0A140T8A3-1" }, "locus": { "chromosome": "26", "start_pos": 25599868, "end_pos": 25588151, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027058.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027058.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027058.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027058.5" } ] } }, { "isoform_ac": "A0AAA9TJC3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJC3/entry", "sequence": { "sequence": "MRLSPRSLCAAVRAAWRESFPLEGRDVARWFPGHMAKGLKKMQSSLRLVDCIIEVHDARIPLSGRNPLFQETLGLKPHLLVLNKMDLADLKEQQKIIQHLEREGIKHVVFTNCVKDENVKQVIPTVTELVGSSYRYHRGEVCERPLMFLLDTPGVLAPRIPSVETGLKLALCGTVLDHLVGEETLADFLLYTLNRHQLSGYVQHYGLGEACDDIASVLKRVAVKLRKTQKVKVLTGTGNVNVIQPDYPAAARDFLRAFRSGLLGPVMLDRDLLQGRSAEES", "length": 281, "header": "tr|A0AAA9TJC3-1|A0A140T8A3_BOVIN Computationally mapped isoform of Mitochondrial GTPase 1 OS=Bos taurus OX=9913 GN=MTG1 PE=3 SV=1 CANONICAL=A0A140T8A3-1" }, "locus": { "chromosome": "26", "start_pos": 25599868, "end_pos": 25588151, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121005.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121005.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096344.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096344.1" } ] } }, { "isoform_ac": "A0AAA9TYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYU9/entry", "sequence": { "sequence": "MQMPRGGGGGMRYIDQDSWEALVLSDQIFWQLNSGLVTKPSVELCLFLPPSFLFEEPREGAALPLVRRRRRGPAEARWPSGGGPVCVTRQGKETLGLKPHLLVLNKMDLADLKEQQKIIQHLEREGIKHVVFTNCVKDENVKQVIPTVTELVGSSYRYHRGEHVEYCIMVIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSRIQVCERPLMFLLDTPGVLAPRIPSVETGLKLALCGTVLDHLVGEETLADFLLYTLNRHQLSGYVQHYGLGEACDDIASVLKRVAVKLRKTQKVKVLTGTGNVNVIQPDYPAAARDFLRAFRSGLLGPVMLDRDLLQGRSAEES", "length": 354, "header": "tr|A0AAA9TYU9-1|A0A140T8A3_BOVIN Computationally mapped isoform of Mitochondrial GTPase 1 OS=Bos taurus OX=9913 GN=MTG1 PE=3 SV=1 CANONICAL=A0A140T8A3-1" }, "locus": { "chromosome": "26", "start_pos": 25596443, "end_pos": 25588151, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100457.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100457.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102412.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102412.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MF45-1", "protein_name": "Mitochondrial GTPase 1", "gene_name": "Mtg1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLWPQAWGAVGAAWRECFPLQGHDVARWFPGHMAKGLKKMQSSLKLVDCVIEVHDARIPLSGRNSLFQELLGLKPHLLVLNKMDLADLTEQQKIVQHLEGKGLKNVIFTNCVKDENIKQIIPKLMELIKYSYRYNRAENMEYCVMVIGVPNVGKSSLINSLRRQHLRTGKATRVGGEPGITRAVTSRIQVCERPLTFLLDTPGVLAPRIESVETGLKLALCGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYGLASACDHIEWVLKNVAVKLGKTRKVKVLTGTGNVNVIQPDYAMAARDFLRTFRSGLLGQVMLDRDLIPVCG", "length": 327 }, "evidence": [ { "id": "A0A140T8A3", "url": "https://omabrowser.org/oma/group/A0A140T8A3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E9PTB3-1", "protein_name": "Mitochondrial GTPase 1", "gene_name": "Mtg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLWPQAWSAVGAAWRECFPLQGHDVARWFPGHMAKGLKKMQSSLKLVDCVIEVHDARYIPFSGRNPLFQELLGLKPHLLVLNKMDLADLTEQQKIVQHLEEKGLRNVIFTNCIKDENIKQIIPKVTELIGCSYRYHRAENPEYCIMVVGVPNVGKSSLINSLRRQHLRTGKAARVGGEPGITRAVTSRIQVCERPLMFLLDTPGVLAPRIQSVETGLKLALCAACLAGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALASASDHIEWVLKNVAIKLGKTRKVKVLTGTGNVNVIQPDYAIAARDFLRTFRSGRLGQVMLDRDIIPAC", "length": 332 }, "evidence": [ { "id": "A0A140T8A3", "url": "https://omabrowser.org/oma/group/A0A140T8A3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03151-1", "protein_name": "Mitochondrial GTPase 1", "gene_name": "MTG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHINVRGTRKIISNVSSFTPRYEFPKYSMPLTDFKGHQVKALKTFEKLLPQMNMIIELRDIRAPLSTRNVVFDRIARKEHDVMKLVVYTRKDLMPGNKPYIGKLKNWHEELGEKFILLDCRNKTDVRNLLKILEWQNYELETNGGYLPMGYRALITGMPNVGKSTLINSLRTIFHNQVNMGRKFKKVAKTGAEAGVTRATSEVIRVTSRNTESRNEIYLIDTPGIGVPGRVSDHNRMLGLALCGSVKNNLVDPIFQADYLLYLMNLQNLNDGRTELYPGSTNSPTNDIYDVLRRLQVNKSQNEKSTAIEWTNKWRLHGKGIIFDPEVLLNNDEFSYKNYVNDQLEKLGDLSYEGLSNKLKGNPNQVF", "length": 367 }, "evidence": [ { "id": "A0A140T8A3", "url": "https://omabrowser.org/oma/group/A0A140T8A3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8R2R6-1", "protein_name": "Mitochondrial ribosome-associated GTPase 1", "gene_name": "Mtg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLWPQAWGAVRGAWRECFPLQGHDVARWFPGHMAKGLKKMQSSLKSVDCVIEVHDARIPFSGRNPLFQELLGLKPHLLVLNKMDLADLTEQQKIVQRLEEKGLSNVLFTNCVKDENIKQIVPKVMELIRCSYRYHRAETPEYCIMVVGVPNVGKSSLINSLRRQHLRTGKAARVGGEPGITRAVTSRIQVCERPLVFLLDTPGVLAPRIESVETGLKLALCGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALASACDQIEWVLKNVAIKLRKTRKVKVLTGTGNVNVIQPDYAMAARDFLRTFRSGLLGQVMLDRDIIPAC", "length": 326 }, "evidence": [ { "id": "A0A140T8A3", "url": "https://omabrowser.org/oma/group/A0A140T8A3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BT17-1", "protein_name": "Mitochondrial ribosome-associated GTPase 1", "gene_name": "MTG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLTPRALCSAAQAAWRENFPLCGRDVARWFPGHMAKGLKKMQSSLKLVDCIIEVHDARIPLSGRNPLFQETLGLKPHLLVLNKMDLADLTEQQKIMQHLEGEGLKNVIFTNCVKDENVKQIIPMVTELIGRSHRYHRKENLEYCIMVIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSKIQVSERPLMFLLDTPGVLAPRIESVETGLKLALCGTVLDHLVGEETMADYLLYTLNKHQRFGYVQHYGLGSACDNVERVLKSVAVKLGKTQKVKVLTGTGNVNIIQPNYPAAARDFLQTFRRGLLGSVMLDLDVLRGHPPAETLP", "length": 334 }, "evidence": [ { "id": "A0A140T8A3", "url": "https://omabrowser.org/oma/group/A0A140T8A3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VCU5-1", "protein_name": "Mitochondrial ribosome-associated GTPase 1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAQLNPFRNAFRLPSKQRINWFPGHMTKGMRQIQQKLRNVDCIVEIHDARIPLAGRNSQFFDTITGSGVKPHILVLNKVDLLGAKQQKSVLQQLRRQQPELQHILFTNCKDQRNNGVLDILPLATRLVSESSRFNRTQAAEHNLMIIGVPNVGKSSVINVLRNVHLKKKSAARVGAEAGITRSVGERIKIQENPPVYMIDTPGILQPSIKDDEMGMKLALVGCLPDHIVGEDLIADYLLYWLNSHRKYDYVEMLKLSSGPSDDISAVLAEYAHREELFHKVKQYDGRVEVMTNLLAAARKFIHFFRSGQLGHMNLDEPSGFR", "length": 323 }, "evidence": [ { "id": "A0A140T8A3", "url": "https://omabrowser.org/oma/group/A0A140T8A3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" }, { "name": "mitochondrial ribosome", "id": "GO:0005761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005761", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of mitochondrial translation", "id": "GO:0070129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070129", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" }, { "name": "regulation of respiratory system process", "id": "GO:0044065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044065", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" }, { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A140T8A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A3" }, { "id": "PS51721", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51721" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CP-type G", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 209, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LKG0-1", "uniprot_ac": "A0A3Q1LKG0", "uniprot_id": "A0A3Q1LKG0_BOVIN", "mass": { "chemical_mass": 149718.0, "monoisotopic_mass": 149718.0 }, "refseq": { "ac": "XP_024835916", "name": "misshapen-like kinase 1 isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835916" }, "gene_names": [ { "name": "MINK1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "name": "MINK1", "type": "synonym", "evidence": [ { "id": "XP_024835916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835916" } ] }, { "name": "MINK", "type": "synonym", "evidence": [ { "id": "XP_024835916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835916" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0/entry#names_and_taxonomy" } ] }, { "name": "misshapen-like kinase 1 isoform X9", "type": "synonym", "evidence": [ { "id": "XP_024835916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835916" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MINK1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0", "locus": { "chromosome": "19", "start_pos": 26489835, "end_pos": 26536859, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004907", "url": "https://www.ensembl.org/id/ENSBTAG00000004907" } ] } } ], "crossref": [ { "id": "ENSBTAG00000004907", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06636", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06636", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519558", "url": "https://www.ncbi.nlm.nih.gov/gene/519558", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKG0", "url": "https://www.orthodb.org/?gene=A0A3Q1LKG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LTD6", "url": "https://www.orthodb.org/?gene=A0A3Q1LTD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6Q3P6", "url": "https://www.orthodb.org/?gene=F6Q3P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47096:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47096:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024835916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835916", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTD6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q3P6", "url": "https://www.uniprot.org/uniprotkb/F6Q3P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q3P6-1", "url": "https://www.uniprot.org/uniprotkb/F6Q3P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKAYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQILPGDRKPLYHYGRGINPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAVPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGSPKPPGPPAPPPGPPNACSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGASSKLDNSPVLSPGNKTKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEEVESSEDEEEESNGEPSEGSRDAPGARSDGDTDSVSTMVVHDVEEIAGPQTPYGGGTMVVQRTPEEERSLLHADSNGYTNLPDVVQPSHSPTESSKGQSPPLKDGGSDYQSRGLVKAPGKSSFTMFVDLGIYQPGGSGDTIPITALVGGEGSRLDQLQYDVRKGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "length": 1331, "header": "tr|A0A3Q1LKG0-1|A0A3Q1LKG0_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MINK1 PE=3 SV=2 CANONICAL=A0A3Q1LKG0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0/entry", "sequence": { "sequence": "MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKAYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQILPGDRKPLYHYGRGINPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAVPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGSPKPPGPPAPPPGPPNACSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGASSKLDNSPVLSPGNKTKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEEVESSEDEEEESNGEPSEGSRDAPGARSDGDTDSVSTMVVHDVEEIAGPQTPYGGGTMVVQRTPEEERSLLHADSNGYTNLPDVVQPSHSPTESSKGQSPPLKDGGSDYQSRGLVKAPGKSSFTMFVDLGIYQPGGSGDTIPITALVGGEGSRLDQLQYDVRKGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "length": 1331, "header": "tr|A0A3Q1LKG0-1|A0A3Q1LKG0_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MINK1 PE=3 SV=2 CANONICAL=A0A3Q1LKG0-1" }, "locus": { "chromosome": "19", "start_pos": 26536657, "end_pos": 26490593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077655.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077655.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057130.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057130.2" } ] } }, { "isoform_ac": "A0A3Q1LTD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTD6/entry", "sequence": { "sequence": "MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKAYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQILPGDRKPLYHYGRGINPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAVPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGASSKLDNSPVLSPGNKTKPDDHRSRPGRPASYKRAIGEDFVLLKERTLDEAPRPPKKAMDYSSSSEEVESSEDEEEESNGEPSEGSRDAPGARSDGDTDSVSTMVVHDVEEIAGPQTPYGGGTMVVQRTPEEERSLLHADSNGYTNLPDVVQPSHSPTESSKGQSPPLKDGGSDYQSRGLVKAPGKSSFTMFVDLGIYQPGGSGDTIPITALVGGEGSRLDQLQYDVRKGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHVSLAGLRAEWGPRPGPSLGASHPLSPPQIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "length": 1330, "header": "tr|A0A3Q1LTD6-1|A0A3Q1LTD6_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MINK1 PE=3 SV=2 CANONICAL=A0A3Q1LKG0-1" }, "locus": { "chromosome": "19", "start_pos": 26536657, "end_pos": 26490593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087237.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087237.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063719.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063719.2" } ] } }, { "isoform_ac": "F6Q3P6-1", "url": "https://www.uniprot.org/uniprotkb/F6Q3P6/entry", "sequence": { "sequence": "MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKAYLSRPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQILPGDRKPLYHYGRGINPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAVPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGSPKPPGPPAPPPGPPNACSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGASSKLDNSPVLSPGNKTKPDDHRSRPGRPASYKRAIGEDFVLLKERTLDEAPRPPKKAMDYSSSSEEVESSEDEEEESNGEPSEGSRDAPGARSDGDTDSVSTMVVHDVEEIAGPQTPYGGGTMVVQRTPEEERSLLHADSNGYTNLPDVVQPSHSPTESSKGQSPPLKDGGSDYQSRGLVKAPGKSSFTMFVDLGIYQPGGSGDTIPITALVGGEGSRLDQLQYDVRKGSVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKNSVEVYAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW", "length": 1339, "header": "tr|F6Q3P6-1|A0A3Q1LKG0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MINK1 PE=3 SV=3 CANONICAL=A0A3Q1LKG0-1" }, "locus": { "chromosome": "19", "start_pos": 26536657, "end_pos": 26490593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017318.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017318.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017318.7", "url": "https://www.ensembl.org/id/ENSBTAP00000017318.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 628, "start_aa": "Thr", "end_pos": 628, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr628", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "regulation of cell-cell adhesion", "id": "GO:0022407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022407", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "regulation of cell-matrix adhesion", "id": "GO:0001952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001952", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { 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"E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-BTA-3225851", "name": "ROS oxidize thioredoxin and activate MAP3K5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1250243" ], "output_participant_list": [ "R-BTA-167709" ], "enzyme_list": [ "F1MI60-1", "F1MXH6-1", "A0A3Q1LKG0-1" ], "evidence": [ { "id": "R-BTA-3225851", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3225851" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1250243", "participant_name": "ROS [cytosol]", "crossref": [ { "id": "26523", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-BTA-167709", "participant_name": "MAP3K5 [cytosol]", "crossref": [ { "id": "ENSBTAP00000011949", "database": "ENSEMBL", "url": "" }, { "id": "NP_001137553.2", "database": "RefSeq", "url": "" }, { "id": "F1MXH6", "database": "UniProt", "url": "" }, { "id": "ENSBTAT00000011949", "database": "ENSEMBL", "url": "" }, { "id": "31198", "database": "VGNC", "url": "" }, { "id": "ENSBTAG00000009065", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] } ] }, { "uniprot_ac": "A0A3Q1M1Z0", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] } ] }, { "uniprot_ac": "A0A3Q1M2U5", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] } ] }, { "uniprot_ac": "A0A3Q1M334", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] } ] }, { "uniprot_ac": "A0A3Q1M4N6", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] } ] }, { "uniprot_ac": "A0A3Q1M4X3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] } ] }, { "uniprot_ac": "A0A3Q1M5T5", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M5T5", "database": 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"https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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}, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": 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"https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": 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"uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 47", "type": "synonym", "evidence": [ { "id": "NP_001192963", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192963" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBM47", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5", "locus": { "chromosome": "6", "start_pos": 59387155, "end_pos": 59495126, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002356", "url": "https://www.ensembl.org/id/ENSBTAG00000002356" } ] } } ], "crossref": [ { "id": "A0A3Q1LLQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LLQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002356", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12485", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12485", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12491", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12491", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12497", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540831", "url": "https://www.ncbi.nlm.nih.gov/gene/540831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540831", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEHMINP", "url": "https://omabrowser.org/oma/group/VEHMINP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RYN2", "url": "https://www.orthodb.org/?gene=F6RYN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192963", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192963", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RYN2", "url": "https://www.uniprot.org/uniprotkb/F6RYN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RYN2-1", "url": "https://www.uniprot.org/uniprotkb/F6RYN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAEDSTAAMSSDSATGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFETVGRIYELRLMMDFDGKNRGYAFVMYCHKNEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFASREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAAKGGGAAEAAVVQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEISAVNPVAIKPGTVAIPAIGAQYSMFQAAPAPKMIEDGKIHTMEHMISPIAVQPDPASAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIHDVYQTY", "length": 591, "header": "tr|A0A3Q1LLQ5-1|A0A3Q1LLQ5_BOVIN Isoform 1 of RNA-binding protein 47 OS=Bos taurus OX=9913 GN=RBM47 PE=1 SV=1 CANONICAL=A0A3Q1LLQ5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5/entry", "sequence": { "sequence": "MTAEDSTAAMSSDSATGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFETVGRIYELRLMMDFDGKNRGYAFVMYCHKNEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFASREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAAKGGGAAEAAVVQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEISAVNPVAIKPGTVAIPAIGAQYSMFQAAPAPKMIEDGKIHTMEHMISPIAVQPDPASAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIHDVYQTY", "length": 591, "header": "tr|A0A3Q1LLQ5-1|A0A3Q1LLQ5_BOVIN Isoform 1 of RNA-binding protein 47 OS=Bos taurus OX=9913 GN=RBM47 PE=1 SV=1 CANONICAL=A0A3Q1LLQ5-1" }, "locus": { "chromosome": "6", "start_pos": 59400252, "end_pos": 59389719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073219.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073219.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057526.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057526.1" } ] } }, { "isoform_ac": "F6RYN2-1", "url": "https://www.uniprot.org/uniprotkb/F6RYN2/entry", "sequence": { "sequence": "MTAEDSTAAMSSDSATGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFETVGRIYELRLMMDFDGKNRGYAFVMYCHKNEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFASREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAAKGGGAAEAAVVQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKVAIPAIGAQYSMFQAAPAPKMIEDGKIHTMEHMISPIAVQPDPASAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIHDVYQTY", "length": 522, "header": "tr|F6RYN2-1|A0A3Q1LLQ5_BOVIN Computationally mapped isoform of RNA-binding protein 47 OS=Bos taurus OX=9913 GN=RBM47 PE=1 SV=2 CANONICAL=A0A3Q1LLQ5-1" }, "locus": { "chromosome": "6", "start_pos": 59400252, "end_pos": 59389719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003040.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003040.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003040.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003040.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540831", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NHK4-1", "protein_name": "RNA-binding protein 47", "gene_name": "rbm47", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTAEDSASAVAMSNPSPSSSSKSSSGHPQHHCTVPEGVAGAPNEAALVSLMERSGYGMVQENGQRKYGPPPGWQGTSPPRGCEIFVGKIPRDVYEDELVPVFESVGRIYEMRLMMDFDGKNRGYAFVMYTQKHEAKRAVRELNNFEIRPGRLLGVCSSVDNCRLFIGGIPKTKKREEILEEVSKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETSEEILRQTFGQFNPGCVERVKKIRDYAFVHFASRDDAVVAMDNLNGTEIEGSRIEVTLAKPVDKEQYTRYQKASKGTAAATTVESTQQSYVYQCDPYTLAYYGYPYNTLIGPNRDYFIKGTVRGRGRAGASSRGPGPRGSYLGGYSAGRGIYSRYHEGKTKLPDKPYEIMSNLELAAVNPVGIKPGTMALPALGAQYPTVFSAAPATKLMEEGKIHPVEHLINPLALQHDPTAASATAAVIPAVSTPPPFQGRPITPVYAMAHNIQRIPAAAASLYGAGYMPIAAHANTATLAALQKNAAVAAAYGGYAGYMPQAFPAATFQMPIHDVYQTY", "length": 600 }, "evidence": [ { "id": "A0A3Q1LLQ5", "url": "https://omabrowser.org/oma/group/A0A3Q1LLQ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AV96-1", "protein_name": "RNA-binding protein 47", "gene_name": "RBM47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEIPTVNPVAIKPGTVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQTY", "length": 593 }, "evidence": [ { "id": "A0A3Q1LLQ5", "url": "https://omabrowser.org/oma/group/A0A3Q1LLQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66H68-1", "protein_name": "RNA-binding protein 47", "gene_name": "Rbm47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAEDSTTAMNSDPTVGSSTKVPEGVAGAPNEAALLALMERTGYNMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFETVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRGEILEEIAKVTEGVLNVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMQTVKILYVRNLMIETTEETIKRSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAAKGGGGSAEAVAQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKTGSIRGRGRGAAGNRTPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEISAVNPVAIKPGTVAIPAIGAQYSMFQAAPAPKIIEDGKIHTMEHMISPIAVQPDPATAAAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTVAPNVPRIPTAGIYGASYVPFAAPATATIATLQKNAAAAVYGGYAGYIPQAFPAALQVPIHDVYQTY", "length": 590 }, "evidence": [ { "id": "A0A3Q1LLQ5", "url": "https://omabrowser.org/oma/group/A0A3Q1LLQ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WT8-1", "protein_name": "RNA-binding protein 47", "gene_name": "Rbm47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAEDSATAMNSDPTVGSSTKVPEGVAGAPNEAALLALIERTGYTMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFETVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRGEILEEIAKVTEGVLNVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMQTVKILYVRNLMIETTEETIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAAKGGGGSAEAVAQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKTGSIRGRGRGAAGNRTPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEISPVNPVAIKPGTVAIPAIGAQYSMFQAAPAPKIIEDGKIHTMEHMISPIAVQPDPATAAAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPATATIATLQKNAAAAVYGGYAGYIPQAFPAALQVPIHDVYQTY", "length": 590 }, "evidence": [ { "id": "A0A3Q1LLQ5", "url": "https://omabrowser.org/oma/group/A0A3Q1LLQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "apolipoprotein B mRNA editing enzyme complex", "id": "GO:0030895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030895", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "cytidine to uridine editing", "id": "GO:0016554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016554", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA stabilization", "id": "GO:0070935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070935", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "positive regulation of interleukin-10 production", "id": "GO:0032733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032733", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "positive regulation of type I interferon-mediated signaling pathway", "id": "GO:0060340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060340", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LLQ5", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class III", "id": "GO:0035032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035032", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLF0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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}, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LK41", "locus": { "chromosome": "22", "start_pos": 45518309, "end_pos": 44539432, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010029", "url": "https://www.ensembl.org/id/ENSBTAG00000010029" } ] } } ], "crossref": [ { "id": "A0A3Q1LK41", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LK41", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010029", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010029", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "537173", "url": "https://www.ncbi.nlm.nih.gov/gene/537173", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LK41", "url": "https://www.orthodb.org/?gene=A0A3Q1LK41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LZ99", "url": "https://www.orthodb.org/?gene=A0A3Q1LZ99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M235", "url": "https://www.orthodb.org/?gene=A0A3Q1M235", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1ME96", "url": "https://www.orthodb.org/?gene=A0A3Q1ME96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MTI4", "url": "https://www.orthodb.org/?gene=F1MTI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18861:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18861:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LK41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK41-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZ99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZ99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M235", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M235", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M235-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M235-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ME96", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ME96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1ME96-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ME96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYY1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T098", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T098", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T098-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T098-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTI4", "url": "https://www.uniprot.org/uniprotkb/F1MTI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTI4-1", "url": "https://www.uniprot.org/uniprotkb/F1MTI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 957, "header": "tr|A0A3Q1LK41-1|A0A3Q1LK41_BOVIN Isoform 1 of ELKS/RAB6-interacting/CAST family member 2 OS=Bos taurus OX=9913 GN=ERC2 PE=4 SV=3 CANONICAL=A0A3Q1LK41-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK41-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK41/entry", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 957, "header": "tr|A0A3Q1LK41-1|A0A3Q1LK41_BOVIN Isoform 1 of ELKS/RAB6-interacting/CAST family member 2 OS=Bos taurus OX=9913 GN=ERC2 PE=4 SV=3 CANONICAL=A0A3Q1LK41-1" }, "locus": { "chromosome": "22", "start_pos": 45336800, "end_pos": 44578810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083526.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083526.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056862.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056862.3" } ] } }, { "isoform_ac": "A0A3Q1LZ99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ99/entry", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKEAPSFNFDPDLVWQDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQLSEGLTKGQAQLCSNILIIYCSAAHISVHHHRERARRLKRSFHFHY", "length": 1005, "header": "tr|A0A3Q1LZ99-1|A0A3Q1LK41_BOVIN Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Bos taurus OX=9913 GN=ERC2 PE=4 SV=2 CANONICAL=A0A3Q1LK41-1" }, "locus": { "chromosome": "22", "start_pos": 45517305, "end_pos": 44578810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086838.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086838.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062639.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062639.2" } ] } }, { "isoform_ac": "A0A3Q1M235-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M235/entry", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQNARYTLCLNGGEITHCVPCAFQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQAYRPKKQPLTSNIPCSCDASYSPDITAKYHGSSYDAYMIQRSQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 1018, "header": "tr|A0A3Q1M235-1|A0A3Q1LK41_BOVIN Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Bos taurus OX=9913 GN=ERC2 PE=4 SV=2 CANONICAL=A0A3Q1LK41-1" }, "locus": { "chromosome": "22", "start_pos": 45336800, "end_pos": 44578810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085180.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085180.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067439.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067439.2" } ] } }, { "isoform_ac": "A0A3Q1ME96-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ME96/entry", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKEAPSFNFDPDLVWQDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 967, "header": "tr|A0A3Q1ME96-1|A0A3Q1LK41_BOVIN Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Bos taurus OX=9913 GN=ERC2 PE=4 SV=3 CANONICAL=A0A3Q1LK41-1" }, "locus": { "chromosome": "22", "start_pos": 45336800, "end_pos": 44578810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086823.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086823.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072479.3", "url": "https://www.ensembl.org/id/ENSBTAP00000072479.3" } ] } }, { "isoform_ac": "A0AAA9RYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYY1/entry", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQMIQLCRRHGGTVKSHAVH", "length": 963, "header": "tr|A0AAA9RYY1-1|A0A3Q1LK41_BOVIN Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Bos taurus OX=9913 GN=ERC2 PE=4 SV=1 CANONICAL=A0A3Q1LK41-1" }, "locus": { "chromosome": "22", "start_pos": 45416027, "end_pos": 44578810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092191.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092191.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076507.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076507.1" } ] } }, { "isoform_ac": "A0AAA9T098-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T098/entry", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKEAPSFNFDPDLVWQDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQAYRPKKQPLTSNIPCSCDASYSPDITAKYHGSSYDAYMIQRSQHHENALLDSRKD", "length": 969, "header": "tr|A0AAA9T098-1|A0A3Q1LK41_BOVIN Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 2 OS=Bos taurus OX=9913 GN=ERC2 PE=4 SV=1 CANONICAL=A0A3Q1LK41-1" }, "locus": { "chromosome": "22", "start_pos": 45290788, "end_pos": 44578810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101345.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101345.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089935.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089935.1" } ] } }, { "isoform_ac": "F1MTI4-1", "url": "https://www.uniprot.org/uniprotkb/F1MTI4/entry", "sequence": { "sequence": "MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTSSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESTLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRMKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRTERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDEDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA", "length": 965, "header": 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] } ], "protein_names": [ { "name": "Teneurin-1", "type": "recommended", "evidence": [ { "id": "G5E5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W9/entry#names_and_taxonomy" } ] }, { "name": "Protein Odd Oz/ten-m homolog 1", "type": "synonym", "evidence": [ { "id": "G5E5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W9/entry#names_and_taxonomy" } ] }, { "name": "Tenascin-M1", "type": "synonym", "evidence": [ { "id": "G5E5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W9/entry#names_and_taxonomy" } ] }, { "name": "Teneurin transmembrane protein 1", "type": "synonym", "evidence": [ { "id": "G5E5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W9/entry#names_and_taxonomy" } ] }, { "name": "teneurin-1 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_005227506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227506" } ] } ], "function": [ { "annotation": "Induces gene transcription activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRM3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM3#function" }, { "database": "UniProtKB", "id": "ARBA00057184", "url": "https://www.uniprot.org/uniprotkb/ARBA00057184#function" }, { "database": "UniProtKB", "id": "A0A3Q1M5M7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5M7#function" }, { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9#function" }, { "database": "UniProtKB", "id": "G5E661", "url": "https://www.uniprot.org/uniprotkb/G5E661#function" } ] }, { "annotation": "Involved in neural development, regulating the establishment of proper connectivity within the nervous system. 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Activates the mitogen-activated protein (MAP) kinase 2 (MEK2) and extracellular signal-regulated kinase (ERK) cascade. 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005227506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRM3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5M7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5W9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E661", "url": "https://www.uniprot.org/uniprotkb/G5E661", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E661-1", "url": "https://www.uniprot.org/uniprotkb/G5E661-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQSRTRKEVEKSTQEMEFCETPHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFSKPYRCCNWKCTALSATAVTVTLALLLAYVIAVHLFGLTWQLQPAEGQLYENGVSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSRSSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSGHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFLLETGTCSCDPKWTGADCSTELCTMECGSHGVCARGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYVSPLCQGSPDPLDLIQQSQSLLSQHTLRLFYDRIKFLIGKDSTHVIPPEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVMSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEILIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAVNLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPDFILWEKRTVILQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIATIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPMSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDASGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGDVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVSPDGSLRVTFASGMEISLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNISAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPVLWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDVFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSPGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVIAGRWTTPNHHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELENLELTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYGDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR", "length": 2732, "header": "tr|G5E5W9-1|G5E5W9_BOVIN Isoform 1 of Teneurin-1 OS=Bos taurus OX=9913 GN=TENM1 PE=3 SV=3 CANONICAL=G5E5W9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM3/entry", "sequence": { "sequence": "MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQSRTRKEVEKSTQEMEFCETPHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFSKPYRCCNWKCTALSATAVTVTLALLLAYVIAVHLFGLTWQLQPAEGQLYENGVSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSRSSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSGHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFLLETGTCSCDPKWTGADCSTELCTMECGSHGVCARGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYVSPLCQGSPDPLDLIQQSQSLLSQHTLRLFYDRIKFLIGKDSTHVIPPEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVMSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEILIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAVNLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPDFILWEKRTVILQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIATIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELSTSPAHKYYLAMDPMSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDASGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGDVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVSPDGSLRVTFASGMEISLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNISAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPVLWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDVFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSPGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVIAGRWTTPNHHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELENLELTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYGDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR", "length": 2717, "header": "tr|A0A3Q1LRM3-1|A0A3Q1LRM3_BOVIN Computationally mapped isoform of Teneurin-1 OS=Bos taurus OX=9913 GN=TENM1 PE=3 SV=2 CANONICAL=G5E5W9-1" }, "locus": { "chromosome": "X", "start_pos": 9308771, "end_pos": 8664885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081102.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081102.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062925.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062925.2" } ] } }, { "isoform_ac": "A0A3Q1M5M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5M7/entry", "sequence": { "sequence": "MEAQAGSTQVSEAGKSKIKKAAGPVSDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFSKPYRCCNWKCTALSATAVTVTLALLLAYVIAVHLFGLTWQLQPAEGQLYENGVSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSRSSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSGHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFLLETGTCSCDPKWTGADCSTELCTMECGSHGVCARGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYVSPLCQGSPDPLDLIQQSQSLLSQHTLRLFYDRIKFLIGKDSTHVIPPEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVMSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEILIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAVNLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPDFILWEKRTVILQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIATIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPMSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDASGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGDVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVSPDGSLRVTFASGMEISLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNISAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPVLWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDVFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSPGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVIAGRWTTPNHHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELENLELTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYGDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR", "length": 2572, "header": "tr|A0A3Q1M5M7-1|G5E5W9_BOVIN Computationally mapped isoform of Teneurin-1 OS=Bos taurus OX=9913 GN=TENM1 PE=3 SV=2 CANONICAL=G5E5W9-1" }, "locus": { "chromosome": "X", "start_pos": 9219985, "end_pos": 8664885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084087.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084087.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065229.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065229.2" } ] } }, { "isoform_ac": "G5E5W9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5W9/entry", "sequence": { "sequence": "MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQSRTRKEVEKSTQEMEFCETPHTLCSGYQTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAQAGSTQDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRSQPSPAAPAPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFSKPYRCCNWKCTALSATAVTVTLALLLAYVIAVHLFGLTWQLQPAEGQLYENGVSKGNRGTESMDTTYSPIGGKVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSRSSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSGHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFLLETGTCSCDPKWTGADCSTELCTMECGSHGVCARGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYVSPLCQGSPDPLDLIQQSQSLLSQHTLRLFYDRIKFLIGKDSTHVIPPEISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRVMSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEILIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPAAVNLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPDFILWEKRTVILQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIATIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPMSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTLNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDASGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGDVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVSPDGSLRVTFASGMEISLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNISAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPVLWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDVFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSPGQHLQFFYADLANPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVIAGRWTTPNHHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPELENLELTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYGDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR", "length": 2732, "header": "tr|G5E5W9-1|G5E5W9_BOVIN Isoform 1 of Teneurin-1 OS=Bos taurus OX=9913 GN=TENM1 PE=3 SV=3 CANONICAL=G5E5W9-1" }, "locus": { "chromosome": "X", "start_pos": 9308771, "end_pos": 8664885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036973.6", "url": "https://www.ensembl.org/id/ENSBTAT00000036973.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036821.6", "url": "https://www.ensembl.org/id/ENSBTAP00000036821.6" } ] } }, { "isoform_ac": "G5E661-1", "url": "https://www.uniprot.org/uniprotkb/G5E661/entry", "sequence": { "sequence": 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"length": 2725, "header": "tr|G5E661-1|G5E661_BOVIN Computationally mapped isoform of Teneurin-1 OS=Bos taurus OX=9913 GN=TENM1 PE=3 SV=3 CANONICAL=G5E5W9-1" }, "locus": { "chromosome": "X", "start_pos": 9308771, "end_pos": 8664885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057265.4", "url": "https://www.ensembl.org/id/ENSBTAT00000057265.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047682.4", "url": "https://www.ensembl.org/id/ENSBTAP00000047682.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 720, "start_aa": "Thr", "end_pos": 720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr720", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "G5E5W9", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1084, "end_pos": 1086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1557, "end_pos": 1559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1574, "end_pos": 1576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1670, "end_pos": 1672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1706, "end_pos": 1708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1764, "end_pos": 1766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1788, "end_pos": 1790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1849, "end_pos": 1851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2063, "end_pos": 2065, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2152, "end_pos": 2154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2292, "end_pos": 2294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2609, "end_pos": 2611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 624, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W9" }, { "id": "PS51361", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Teneurin N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 318, "start_aa": "Met", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 720 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1084, "end_pos": 1086 }, { "start_pos": 1557, "end_pos": 1559 }, { "start_pos": 1574, "end_pos": 1576 }, { "start_pos": 1670, "end_pos": 1672 }, { "start_pos": 1706, "end_pos": 1708 }, { "start_pos": 1764, "end_pos": 1766 }, { "start_pos": 1788, "end_pos": 1790 }, { "start_pos": 1849, "end_pos": 1851 }, { "start_pos": 2063, "end_pos": 2065 }, { "start_pos": 2152, "end_pos": 2154 }, { "start_pos": 2292, "end_pos": 2294 }, { "start_pos": 2609, "end_pos": 2611 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 905, "end_pos": 907 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G8JKV7-1", "uniprot_ac": "G8JKV7", "uniprot_id": "G8JKV7_BOVIN", "mass": { "chemical_mass": 83517.0, "monoisotopic_mass": 83517.0 }, "refseq": {}, "gene_names": [ { "name": "PLOD1", "type": "recommended", "evidence": [ { "id": "G8JKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ] } ], "protein_names": [ { "name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "type": "recommended", "evidence": [ { "id": "G8JKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKV7/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.4", "type": "synonym", "evidence": [ { "id": "G8JKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKV7/entry#names_and_taxonomy" } ] }, { "name": "Lysyl hydroxylase 1", "type": "synonym", "evidence": [ { "id": "G8JKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKV7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M7Y8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Y8#function" }, { "database": "UniProtKB", "id": "ARBA00045361", "url": "https://www.uniprot.org/uniprotkb/ARBA00045361#function" }, { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLOD1", "url": "https://www.uniprot.org/uniprotkb/G8JKV7", "locus": { "chromosome": "16", "start_pos": 41718717, "end_pos": 41748319, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002052", "url": "https://www.ensembl.org/id/ENSBTAG00000002052" } ] } } ], "crossref": [ { "id": "G8JKV7", "url": "https://alphafold.ebi.ac.uk/entry/G8JKV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002052", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002052", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23004", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23004", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TDVACNH", "url": "https://omabrowser.org/oma/group/TDVACNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7Y8", "url": "https://www.orthodb.org/?gene=A0A3Q1M7Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G8JKV7", "url": "https://www.orthodb.org/?gene=G8JKV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10730:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10730:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16569", "url": "https://www.rhea-db.org/rhea/16569", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M7Y8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G8JKV7-1", "url": "https://www.uniprot.org/uniprotkb/G8JKV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLLLLLAPLGWLLLAETKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWPGEAMLAGGGLKVRLLKKALEKHADKENLVILFTDSYDVVFASGPRELLKKFRQARSQVVFSAEELIYPDRRLEAKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGQVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCAVCDEGLRSLKGIGDEALPAVLVGVFIEQPTPFLSLFFQRLLRLHYPQKRLRLFIHNHEQHHKAQVEQFLAEHGDEYQSVKLVGPEVRVANADARNMGADLCRQDRGCTYYFSVDADVALTEPKTLRLLIEQNKNVITPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQETDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHSFGHLLSLDSYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAGKMVEMPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQINFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLVPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "length": 726, "header": "tr|G8JKV7-1|G8JKV7_BOVIN Isoform 1 of Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Bos taurus OX=9913 GN=PLOD1 PE=4 SV=2 CANONICAL=G8JKV7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Y8/entry", "sequence": { "sequence": "MSDSGQRGPPGVQHSERILSSAPKSRDPQCKVQTPLPWVLPAMLVNNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWPGEAMLAGGGLKVRLLKKALEKHADKENLVILFTDSYDVVFASGPRELLKKFRQARSQVVFSAEELIYPDRRLEAKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGQVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCAVCDEGLRSLKGIGDEALPAVLVGVFIEQPTPFLSLFFQRLLRLHYPQKRLRLFIHNHEQHHKAQVEQFLAEHGDEYQSVKLVGPEVRVANADARNMGADLCRQDRGCTYYFSVDADVALTEPKTLRLLIEQNKNVITPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQETDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHSFGHLLSLDSYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAGKMVEMPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQINFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLVPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "length": 746, "header": "tr|A0A3Q1M7Y8-1|G8JKV7_BOVIN Computationally mapped isoform of Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Bos taurus OX=9913 GN=PLOD1 PE=4 SV=2 CANONICAL=G8JKV7-1" }, "locus": { "chromosome": "16", "start_pos": 41739939, "end_pos": 41719458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074750.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074750.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069986.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069986.2" } ] } }, { "isoform_ac": "G8JKV7-1", "url": "https://www.uniprot.org/uniprotkb/G8JKV7/entry", "sequence": { "sequence": "MRLLLLLAPLGWLLLAETKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWPGEAMLAGGGLKVRLLKKALEKHADKENLVILFTDSYDVVFASGPRELLKKFRQARSQVVFSAEELIYPDRRLEAKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGQVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCAVCDEGLRSLKGIGDEALPAVLVGVFIEQPTPFLSLFFQRLLRLHYPQKRLRLFIHNHEQHHKAQVEQFLAEHGDEYQSVKLVGPEVRVANADARNMGADLCRQDRGCTYYFSVDADVALTEPKTLRLLIEQNKNVITPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQETDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHSFGHLLSLDSYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAGKMVEMPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQINFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLVPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "length": 726, "header": "tr|G8JKV7-1|G8JKV7_BOVIN Isoform 1 of Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Bos taurus OX=9913 GN=PLOD1 PE=4 SV=2 CANONICAL=G8JKV7-1" }, "locus": { "chromosome": "16", "start_pos": 41748136, "end_pos": 41719458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002658.5", "url": "https://www.ensembl.org/id/ENSBTAT00000002658.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002658.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002658.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480M584-1", "protein_name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "gene_name": "PLOD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLLLLLAPLGWLLLTETKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNEKEASSGGGLKVRLLKKALEKHADENLVILFTDSYDVVFASGPRELLKKFRQAKSQVVFSAEELIYPDRRLEAKYPAVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKRERINITLDHRCRIFQNLDGALDEVVLKFEMGQVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCSVCDEGLRSLKGIGDEALPTVLVGLFIEQPTPFLSLFFQRLLRLQYPRKRMRLFIHNHEQHHKALVEQFLAEHGDEYQSVKLVGPEVRVANADARNMGADLCRQDRSCTYYFSVDADVALTEPKTLRLLIEQNKNVLAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNVYLIKGSALRAELQQTDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHAFGHLLSLDSYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAGKLVETPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQISFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "length": 725 }, "evidence": [ { "id": "G8JKV7", "url": "https://omabrowser.org/oma/group/G8JKV7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8WIN7-1", "protein_name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "gene_name": "plod1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRGVLAFLACLFASFPPLHCNQQGSIPEGDLLVLTVATQETDGFRRFLRSAKHFNYTIKVLGRGETWRGGDYMTAPGGGQKVRLLKSALEDIQEEKKVILFVDSYDVIFSSGPKELLKKFQQAKHKVVFSAETLIWPDRHLEDKHPHVREGKRFLGAGGFIGYAANLKKMLSDWSGADGDSDQLFYTKIYINKEKRKSINITLDSKCRLFQNLHGALDEVVLKFEDGRVRARNVLYDTLPVIIHGNGPTKLQINYLGNYIPNLWTFETGCTMCNQDRRLLSGLQESEYPVVVIGIFIQQPTPFVTVFFERLFNLKYPKNRLKLFIYNQETHHEQHIHAFLDSHESEYQGVKLIGPEEDIDPVSSRNLGFDMCREDIDCEYFFSIDVDVVLKNEDTLRILIEHNKPFIAPMLTKPGRLWTNFWGALSADGFYARSEDYVDIVQGHRVGLWNVPYVSHIFLIKADTLRTDLKDPDLFKSTTLDPDMAFCEKIRNKGVFMFVTNMDTFGRVLSTDNYQTNHLHNDLWQIFENPVEWEERYIHPNYSRVLKDEFIETPCPDVYWFPIFSEVACDHLVEEMENFGQWSGGANVDNRIQGGYENVPTIDIHMNQVGYEKEWQKFLLDYIAPVTEKMFPGYYTRAQFDLAFVVRYKPDEQPSLRPHHDASTFTINIALNHVGIDFQGGGCRFLRYDCSIRSPRKGWAFMHPGRLTHYHEGLPTTEGVRYIAVSFVDP", "length": 730 }, "evidence": [ { "id": "G8JKV7", "url": "https://omabrowser.org/oma/group/G8JKV7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q02809-1", "protein_name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "gene_name": "PLOD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPLLLLALLGWLLLAEAKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNVEKGTSAGGGQKVRLLKKALEKHADKEDLVILFADSYDVLFASGPRELLKKFRQARSQVVFSAEELIYPDRRLETKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFVSLFFQRLLRLHYPQKHMRLFIHNHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANADARNMGADLCRQDRSCTYYFSVDADVALTEPNSLRLLIQQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHTLGHLLSLDSYRTTHLHNDLWEVFSNPEDWKEKYIHQNYTKALAGKLVETPCPDVYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHKFLLEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP", "length": 727 }, "evidence": [ { "id": "G8JKV7", "url": "https://omabrowser.org/oma/group/G8JKV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63321-1", "protein_name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "gene_name": "Plod1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSLLLLASLAWLLLAQAKDDAKLEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSAAGGPSAAGGGQKVRLLKKALKKYADKEDLVILFVDSYDVVFASGPRELLKKFQQAKSRVVFSAEELIYPDRRLEAKYPTVPDGKRFLGSGGFIGYAPSLSKLVAEWEGQDNDSDQLFYTKIFLDPEKREQINISLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVVIHGNGPTKLQVNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFRRLLHLRYPQKQMRLFIHNQEQHHKLQVEQFLAEHGGEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDADVALTEPNSLRLLIEQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELRHVDLFHYSKLDPDMSFCANVRQQEVFMFLTNRHTFGHLLSLDNYQTTHLHNDLWEVFSNPQDWKEKYIHENYTKALAGKLVETPCPDVYWFPIFTEVACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQITFEREWHKFLVEYIAPLTEKLYPGYYTKAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGEDYEGGGCRFLRYNCSVRAPRKGWALMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "length": 728 }, "evidence": [ { "id": "G8JKV7", "url": "https://omabrowser.org/oma/group/G8JKV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R0E2-1", "protein_name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "gene_name": "Plod1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSLLLLAPLAWLLLVQAKDDAKLEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSVDGGPAAAGGGQKVRLLKKALEKHADKEDLVILFVDSYDVVFASGPRELLKKFQQAKSQVVFSAEEHIYPDRRLEAKYPTVPDGKRFLGSGGFIGYAPSLSKLVAEWEGQDSDSDQLFYTKIFLNPEKREQINISLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVVVHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFLRLLRLRYPQKQMRLFIHNQERHHKLQVEQFLAEHGSEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDADVALTEPNSLRLLIEQNKNVIAPLMTRHGRLWSNFWGGLSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQNVDLFHYSKLDSDMSFCANVRQQEVFMFLTNRHTFGHLLSLDNYQTTHLHNDLWEVFSNPEDWKEKYIHENYTKALAGKLVETPCPDVYWFPIFTEAACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQITFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTVNIALNRVGEDYEGGGCRFLRYNCSVRAPRKGWALLHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "length": 728 }, "evidence": [ { "id": "G8JKV7", "url": "https://omabrowser.org/oma/group/G8JKV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTH0-1", "protein_name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase", "gene_name": "Plod", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRIQQSALLLLLLAVTSQGDAESNWNDKIKVFTVATEPTDGYTRYIRSARVYDIEVTTLGLGEEWKGGDMQKPGGGFKLNLLREAIAPYKNEPETIILFTDSYDVIITTTLDEIFEKFKESGAKILFSAEKYCWPDKSLANDYPEVEGKASRFLNSGAFIGYAPQVFALLVDPIEDTADDQLYFTKIFLDETKRAKLGLKLDVQSRLFQNLHGAKNDVKLKVDLESNQGVLQNVDFMTTPSIIHGNGLSKVDLNAYGNYLARTFNGVCLLCQENLLDLEETNLPVISLALMVTQPVPFFDQFLEGIESLNYPKEKLHLLIYSNVAFHDDDIKSFVNKHAKEYATAKFALSTDELDERQGRQLALDKARLHQSDYIFFVDADAHIDDGEVLRELLRLNKQFVAPIFSKHKELWSNFWGALSEGGYYARSHDYVDIVKRELIGMFNVPHVTSIYLVKKTAFDAISFKHKEFDPDMAMCESLRNAGIFMYASNLRIFGHLVNADDFNTTVTRPDFYTLFSNEIDWTEKYIHPNYSLQLNESNKIQQPCPDVYWFQIVSDAFCDDLVAIMEAHNGWSDGSNNDNRLEGGYEAVPTRDIHMKQVGLERLYLKFLQMFVRPLQERAFTGYFHNPPRALMNFMVRYRPDEQPSLRPHHDSSTYTINIAMNRAGIDYQGGGCRFIRYNCSVTDTKKGWMLMHPGRLTHYHEGLLVTNGTRYIMISFIDP", "length": 721 }, "evidence": [ { "id": "G8JKV7", "url": "https://omabrowser.org/oma/group/G8JKV7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "procollagen-lysine 5-dioxygenase activity", "id": "GO:0008475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008475", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "epidermis development", "id": "GO:0008544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008544", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "collagen biosynthetic process", "id": "GO:0032964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032964", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "hydroxylysine biosynthetic process", "id": "GO:0046947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046947", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "catalytic complex", "id": "GO:1902494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902494", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum membrane", "id": "GO:0030867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030867", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "G8JKV7", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16569", "name": "", "equation": "L-lysyl-[collagen] + 2-oxoglutarate + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G8JKV7-1", "F1MET0-1", "O77588-1" ], "evidence": [ { "id": "16569", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16569" } ] }, { "id": "R-BTA-1981104", "name": "Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MET0-1", "G8JKV7-1" ], "evidence": [ { "id": "R-BTA-1981104", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1981104" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MET0", "gene_name": "PLOD3", "activity": [ { "ec_number": "1.14.11.4", "activity": "L-lysyl-[collagen] + 2-oxoglutarate + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2.", "evidence": [ { "id": "F1MET0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MET0" } ] }, { "ec_number": "1.14.11.4", "activity": "", "evidence": [ { "id": "F1MET0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MET0" } ] } ] }, { "uniprot_ac": "G8JKV7", "gene_name": "PLOD1", "activity": [ { "ec_number": "1.14.11.4", "activity": "L-lysyl-[collagen] + 2-oxoglutarate + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2.", "evidence": [ { "id": "G8JKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ] }, { "ec_number": "1.14.11.4", "activity": "", "evidence": [ { "id": "G8JKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" } ] } ] }, { "uniprot_ac": "O77588", "gene_name": "PLOD1", "activity": [ { "ec_number": "1.14.11.4", "activity": "L-lysyl-[collagen] + 2-oxoglutarate + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2.", "evidence": [ { "id": "O77588", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77588" } ] }, { "ec_number": "1.14.11.4", "activity": "", "evidence": [ { "id": "O77588", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77588" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G8JKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G8JKV7" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 635, "end_pos": 726, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.4", "ec_name": "L-lysyl-[collagen] + 2-oxoglutarate + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2.", "evidence": [ { "id": "1.14.11.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.4" }, { "id": "1.14.11.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 685, "end_pos": 687 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DA7-1", "uniprot_ac": "Q08DA7", "uniprot_id": "QTMAN_BOVIN", "mass": { "chemical_mass": 42174.0, "monoisotopic_mass": 42174.0 }, "refseq": { "ac": "NP_001069503", "name": "tRNA-queuosine alpha-mannosyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069503" }, "gene_names": [ { "name": "GTDC1", "type": "recommended", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ] }, { "name": "QTMAN", "type": "recommended", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ] }, { "name": "GTDC1", "type": "synonym", "evidence": [ { "id": "NP_001069503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069503" }, { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ] }, { "name": "QTMAN", "type": "synonym", "evidence": [ { "id": "NP_001069503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069503" } ] } ], "protein_names": [ { "name": "tRNA-queuosine alpha-mannosyltransferase", "type": "recommended", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.110", "type": "synonym", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7/entry#names_and_taxonomy" } ] }, { "name": "Glycosyltransferase-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7/entry#names_and_taxonomy" } ] }, { "name": "QTMAN", "type": "synonym", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7/entry#names_and_taxonomy" } ] }, { "name": "glycosyltransferase-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001069503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069503" } ] }, { "name": "tRNA-queuosine alpha-mannosyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001069503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069503" } ] } ], "function": [ { "annotation": "Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation.", "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7#function" }, { "database": "UniProtKB", "id": "Q4AE62", "url": "https://www.uniprot.org/uniprotkb/Q4AE62#function" }, { "database": "UniProtKB", "id": "A0A3Q1M0M3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0M3#function" }, { "database": "UniProtKB", "id": "ARBA00045402", "url": "https://www.uniprot.org/uniprotkb/ARBA00045402#function" }, { "database": "UniProtKB", "id": "A0A3Q1MK35", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK35#function" }, { "database": "UniProtKB", "id": "A0A3Q1M812", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M812#function" }, { "database": "UniProtKB", "id": "A0AAA9TU65", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU65#function" }, { "database": "UniProtKB", "id": "A0A3Q1MIK2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIK2#function" }, { "database": "UniProtKB", "id": "A0A3Q1NNS7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNS7#function" }, { "database": "UniProtKB", "id": "A0AAA9SYL7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYL7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "QTMAN", "url": "https://www.uniprot.org/uniprotkb/Q08DA7", "locus": {} } ], "crossref": [ { "id": "Q08DA7", "url": "https://alphafold.ebi.ac.uk/entry/Q08DA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001132", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001132", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534677", "url": "https://www.ncbi.nlm.nih.gov/gene/534677", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534677", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534677", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRWEYDK", "url": "https://omabrowser.org/oma/group/HRWEYDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M0M3", "url": "https://www.orthodb.org/?gene=A0A3Q1M0M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MIK2", "url": "https://www.orthodb.org/?gene=A0A3Q1MIK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MK35", "url": "https://www.orthodb.org/?gene=A0A3Q1MK35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q08DA7", "url": "https://www.orthodb.org/?gene=Q08DA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13615:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13615:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069503", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12885", "url": "https://www.rhea-db.org/rhea/12885", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M0M3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M812", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M812-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M812-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIK2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK35", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK35-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NNS7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NNS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYL7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYL7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU65", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU65-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DA7-1", "url": "https://www.uniprot.org/uniprotkb/Q08DA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKGEMAPFSWAALHGKFRSLLTAEPREDL", "length": 366, "header": "sp|Q08DA7-1|QTMAN_BOVIN Isoform 1 of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0M3/entry", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSESRKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKSPEPSRTLCSLWCLQLSS", "length": 442, "header": "tr|A0A3Q1M0M3-1|A0A3Q1M0M3_BOVIN Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=GTDC1 PE=3 SV=2 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52805404, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084490.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084490.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063535.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063535.2" } ] } }, { "isoform_ac": "A0A3Q1M812-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M812/entry", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSREHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSESRKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKGEMAPFSWAALHGKFRSLLTAEPREDL", "length": 340, "header": "tr|A0A3Q1M812-1|QTMAN_BOVIN Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52796470, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070492.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070492.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070011.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070011.2" } ] } }, { "isoform_ac": "A0A3Q1MIK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIK2/entry", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSESRKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKGEMAPFSWAALHGKFRSLLTAEPREDL", "length": 451, "header": "tr|A0A3Q1MIK2-1|QTMAN_BOVIN Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52796470, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082637.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082637.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074138.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074138.1" } ] } }, { "isoform_ac": "A0A3Q1MK35-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK35/entry", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPGWKLCIVGVTHFVPKIWFILKYFQLSICILHLNSFQKGSRISARDQILQENISIRVKWLLFLGQPYMVNSGLCLQQNLGKICDRWG", "length": 407, "header": "tr|A0A3Q1MK35-1|QTMAN_BOVIN Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52796483, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083171.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083171.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071192.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071192.1" } ] } }, { "isoform_ac": "A0A3Q1NNS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNS7/entry", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSESRKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKGEMAPFSWAALHDFFTLLHH", "length": 444, "header": "tr|A0A3Q1NNS7-1|QTMAN_BOVIN Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52825451, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087284.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087284.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074584.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074584.2" } ] } }, { "isoform_ac": "A0AAA9SYL7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYL7/entry", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSESRKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKICSLWLAAAAAKLLQSCPTLCDPIDGSPPGSPIPGILQVR", "length": 464, "header": "tr|A0AAA9SYL7-1|QTMAN_BOVIN Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52814074, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103673.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103673.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089356.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089356.1" } ] } }, { "isoform_ac": "A0AAA9TU65-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU65/entry", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSESRKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKPQEAYKNEPGLM", "length": 436, "header": "tr|A0AAA9TU65-1|QTMAN_BOVIN Computationally mapped isoform of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52791685, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127978.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127978.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100925.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100925.1" } ] } }, { "isoform_ac": "Q08DA7-1", "url": "https://www.uniprot.org/uniprotkb/Q08DA7/entry#Q08DA7-1", "sequence": { "sequence": "MSILILEAFYGGSHKQLVDLLQEELEDSVLYTLPAKKWHWRARTSALYFSQNIPTSEHYRILFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSIGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKAAHLQKILSLKENGGNAPSTALPFQQQLRGSENLLKSFDSKSGPCDAAQQESLGCSVRQASYLKTFNSSDDSSTHHGEHKQNRCDVLAEADDQQRPLHIVWPHRWLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDITRKHLYKGEMAPFSWAALHGKFRSLLTAEPREDL", "length": 366, "header": "sp|Q08DA7-1|QTMAN_BOVIN Isoform 1 of tRNA-queuosine alpha-mannosyltransferase OS=Bos taurus OX=9913 GN=QTMAN PE=2 SV=1 CANONICAL=Q08DA7-1" }, "locus": { "chromosome": "2", "start_pos": 52796470, "end_pos": 52483953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001505.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001505.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001505.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001505.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity" ], "publication": [], "pathway": [ { "id": "bta:534677", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534677", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y209-1", "protein_name": "tRNA-queuosine alpha-mannosyltransferase", "gene_name": "GTDC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVLLIEAFYGGSHKQLMDLLQEELKEDCVLCTLPAKKWHWKARTAALYFMQTVPASANYRILFASSVLNLAELAALRPDLGKLKKVLYFHENQLAYPVQKCKERDFQYGYNQVLSCLVADTVVFNSAFNMESFLTSIGKFMKLIPDHRPKDLEKIIRPKCQVLYFPVRFPDVSRFMPEHKLAHLENVIGVKRNGDFYQREGLPGQQKSRALGGLMKNSNACRESGLCETQPGLCTTQHEGLHSPLTAAGRLNKSEASESTNPCQEEDKQHVTFNLCNIWSGMDYLQRPLHVVWPHRWEHDKDPETFFKVLLKLKEQELPFHVSVLGETFTDVPDIFAEAKKALGSSVLHWGYLPSKDDYFRALCMADVVISTAKHEFFGVAMVEAVHCGCYPLCPKALVYPEIFPAEYLYSTPEQLFKRLQNFCKRPDIVRKHLYKGEMAGFSWAALRGKFRSLLAAEPREDL", "length": 464 }, "evidence": [ { "id": "Q08DA7", "url": "https://omabrowser.org/oma/group/Q08DA7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q4AE62-1", "protein_name": "tRNA-queuosine alpha-mannosyltransferase", "gene_name": "QTMAN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSILIIEAFYGGSHKQLVDLLQEELGDCVVYTLPAKKWHWRARTSALYFSQTIPISEHYRTLFASSVLNLTELAALRPDLGKLKKILYFHENQLIYPVKKCQERDFQYGYNQILSCLVADVVVFNSVFNMESFLTSMGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKTTHLKKMLGLKGNGGAVLSMALPFQPEQRDSEDLLKNFNSECDTHCGLDTARQEYLGNSLRQESDLKKSTSSDNSSSHHGENKQNLTVDPCDILGGVDNQQRLLHIVWPHRWEHDKDPESFFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPSKDDYFQVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCKRPDIIRKHLYKGEIAPFSWAALHGKFRSLLTTEPREDL", "length": 458 }, "evidence": [ { "id": "Q08DA7", "url": "https://omabrowser.org/oma/group/Q08DA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q53E76-1", "protein_name": "tRNA-queuosine alpha-mannosyltransferase", "gene_name": "Qtman", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSILIIEAFYGGSHRQLVELLREEVDDCVLYTLPAKKWHWRARTAALYFSQSVPSSEHYSLVADVVVFNSNFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLIGNDAAALSVTLPPQPEQRLSKKSLENFESKSDEHPGLDTEQETLDTPTILKSVSLPVSEENPALGHSTFLCGAEDQQRPLHITWPHRWEHDKDPETFLKVLMHLKELRLNFYVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPSKEDYFRVLCTADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLKSFCERPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 389 }, "evidence": [ { "id": "Q08DA7", "url": "https://omabrowser.org/oma/group/Q08DA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BW56-1", "protein_name": "tRNA-queuosine alpha-mannosyltransferase", "gene_name": "Qtman", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSIVIIEAFYGGSHRQLVELLREELDDCVLYTLPAKKWHWRARTAALYFSQNIPSSEHYRTLFASSVLNLTELAALRPDLGKLKKILYFHENQLVYPVKKYQERDFQYGYNQILSCLVADVVVFNSSFNMESFLTSIGKFLKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHKIAHLRRMLSLIGDAAASQSVAPCPQPGQRVSEKSPENCESKSDEHPDLDAEQEALDNPSVHKSGSLPVSKENLPLDPSTLLCGAEDPQRPLHITWPHRWEHDKDPETFLKILMSLKQLNLNFHVSVLGETFTDTPDIFSEAKKALGSSVLHWGYLPRKEDYFRVLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKALVYPEIFPAEYLYSTPEQLSKRLKSFCKRPDIIRKHLYKGEVAPFSWAALHGKFRSLLTTEPREDL", "length": 445 }, "evidence": [ { "id": "Q08DA7", "url": "https://omabrowser.org/oma/group/Q08DA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ], "pmid": "" }, { "name": "tRNA wobble guanine modification", "id": "GO:0002099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002099", "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tRNA-queuosine(34) beta-mannosyltransferase activity", "id": "GO:0016438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016438", "evidence": [ { "database": "UniProtKB", "id": "Q08DA7", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12885", "name": "", "equation": "queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08DA7-1" ], "evidence": [ { "id": "12885", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12885" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q08DA7", "gene_name": "QTMAN", "activity": [ { "ec_number": "2.4.1.110", "activity": "queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+).", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ] }, { "ec_number": "2.4.1.110", "activity": "", "evidence": [ { "id": "Q08DA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DA7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 366, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DA7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DA7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.110", "ec_name": "queuosine(34) in tRNA(Asp) + GDP-alpha-D-mannose = O-4''-alpha-D-mannosylqueuosine(34) in tRNA(Asp) + GDP + H(+).", "evidence": [ { "id": "2.4.1.110", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.110" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 247, "end_pos": 249 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [ "glycogene", "glycosyltransferase" ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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protein-like 4 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193440" }, "gene_names": [ { "name": "CNTNAP4", "type": "recommended", "evidence": [ { "id": "G5E5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" } ] }, { "name": "CNTNAP4", "type": "synonym", "evidence": [ { "id": "NP_001193440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193440" } ] } ], "protein_names": [ { "name": "Contactin associated protein family member 4", "type": "synonym", "evidence": [ { "id": "G5E5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W4/entry#names_and_taxonomy" } ] }, { "name": "contactin associated protein like 4", "type": "synonym", "evidence": [ { "id": "NP_001193440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193440" } ] }, { "name": "contactin-associated protein-like 3B", "type": "synonym", "evidence": [ { "id": "NP_001193440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193440" } ] }, { "name": "contactin-associated protein-like 4 precursor", "type": "synonym", "evidence": [ { "id": "NP_001193440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193440" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5W4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CNTNAP4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4", "locus": { "chromosome": "18", "start_pos": 3704470, "end_pos": 3420676, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000026004", "url": "https://www.ensembl.org/id/ENSBTAG00000026004" } ] } } ], "crossref": [ { "id": "ENSBTAG00000026004", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026004", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536775", "url": "https://www.ncbi.nlm.nih.gov/gene/536775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536775", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536775", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CANTGYM", "url": "https://omabrowser.org/oma/group/CANTGYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LUC1", "url": "https://www.orthodb.org/?gene=A0A3Q1LUC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MUR4", "url": "https://www.orthodb.org/?gene=A0A3Q1MUR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E5W4", "url": "https://www.orthodb.org/?gene=G5E5W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193440", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUC1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUR4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5W4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5W4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSVTGAVLKTLLLLSTPNWNRVLAGNSYNCDDPLVSTLSQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEITAVATQGGYGSSNWVTSYLLMFSDSGRNWKQYRQEDSIWGFVGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSCLLYRFDQKSLSPIKDVISLKFKTMQSDGILLHREGQNGDHITLELRRGKLFLLINSGDAKPPSARAPVRLTLGSLLDDQHWHSVLIQRLGTQVNFTVDGHRRRFRAQGEFSSLHLDYEISFGGIPAPGKPVSFPHKHFHGCLENLFYDGVDIIDLAKRQDPQMIVMGNVSFSCSQPQSVPVTFLSPRSYLALPGSFGEDEISATFQFRTWNKAGLLLFTELQLVSGGLLLFLNDGKLKLHLYHPGKLPSDITAGVGLNDGQWHSVSLSAKRNYLSVVVDGQVASASPSQGPEQIYSGGIFYFGGCPDSSFGSKCKSPLGGFQGCMRLISIRHEVVDLISLQPGALGNFSDLQIDSCGITDRCLPNYCEHGGECSQSWDTFHCNCANTGYRGATCHNSIYEQSCEAYKHKGNTSGFYYIDADGSGPLEPFLLYCNMTETAWTIIQHNGSGVTRVRNTNPENPYTGFFEYVASMEQLQATINRAEHCEQELTYYCKKSRLVSKEDGAPLSWWVGRTNETQTYWGGSLPDPQKCTCGLEGNCVDSQYYCNCDADRNEWTNDTGFLSYKEHLPVTRIVITDTGRPHSEAAYKLGPLLCRGDKLFWNSASFNTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGITDFIRIELRSPAVVTFSFDVGNGPFEISVQSPTHFSDNQWHHVRVERNMKEASVRVDQLSPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGEALDLEERARVTPGVEPGCRGHCSSYGRLCHHGGMCMEKPSGFSCDCTSSAYAGPFCSDEISAYFGSGSSVIYNFQENYSLSKNSSSHAASFHGDTRLSRETIKFSFRTTRTPSLLLYLSSFYKEYLSVILAKNGSLQIRYKLNRYQEPDVVNFDFKNMADGQLHHVKINREEAVVFVEIDESMRRQVHLASGTELSAVRSLVLGRIIEHSDVDQETALAGAQGFLGCLSAVQVSHVAPLKAALQPSRPAPITVSGHVTESSCVAQAGTDATSRERTHSFADHSGTRDDREPLTKTIKSDSAVIGGLIAVVIFILLCIAAIAVRIYQQKRLYKRNEAKRSENVDNAEAVLKSELNIQNPVKENQKEYFF", "length": 1308, "header": "tr|G5E5W4-1|G5E5W4_BOVIN Isoform 1 of Contactin associated protein family member 4 OS=Bos taurus OX=9913 GN=CNTNAP4 PE=3 SV=2 CANONICAL=G5E5W4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUC1/entry", "sequence": { "sequence": "MGSVTGAVLKTLLLLSTPNWNRVLAGNSYNCDDPLVSTLSQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEITAVATQGGYGSSNWVTSYLLMFSDSGRNWKQYRQEDSIWGFVGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSCLLYRFDQKSLSPIKDVISLKFKTMQSDGILLHREGQNGDHITLELRRGKLFLLINSGDAKPPSARAPVRLTLGSLLDDQHWHSVLIQRLGTQVNFTVDGHRRRFRAQGEFSSLHLDYEISFGGIPAPGKPVSFPHKHFHGCLENLFYDGVDIIDLAKRQDPQMIVMGNVSFSCSQPQSVPVTFLSPRSYLALPGSFGEDEISATFQFRTWNKAGLLLFTELQLVSGGLLLFLNDGKLKLHLYHPGKLPSDITAGVGLNDGQWHSVSLSAKRNYLSVVVDGQVASASPSQGPEQIYSGGIFYFGGCPDSSFGSKCKSPLGGFQGCMRLISIRHEVVDLISLQPGALGNFSDLQIDSCGITDRCLPNYCEHGGECSQSWDTFHCNCANTGYRGATCHNSIYEQSCEAYKHKGNTSGFYYIDADGSGPLEPFLLYCNMTETAWTIIQHNGSGVTRVRNTNPENPYTGFFEYVASMEQLQATINRAEHCEQELTYYCKKSRLVSKEDGAPLSWWVGRTNETQTYWGGSLPDPQKCTCGLEGNCVDSQYYCNCDADRNEWTNDTGFLSYKEHLPVTRIVITDTGRPHSEAAYKLGPLLCRGDKLFWNSASFNTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGITDFIRIELRSPAVVTFSFDVGNGPFEISVQSPTHFSDNQWHHVRVERNMKEASVRVDQLSPKTQPAPADGHVLLQLNSQLFVEISAYFGSGSSVIYNFQENYSLSKNSSSHAASFHGDTRLSRETIKFSFRTTRTPSLLLYLSSFYKEYLSVILAKNGSLQIRYKLNRYQEPDVVNFDFKNMADGQLHHVKINREEAVVFVEIDESMRRQVHLASGTELSAVRSLVLGRIIEHSDVDQETALAGAQGFLGCLSAVQVSHVAPLKAALQPSRPAPITVSGHVTESSCVAQAGTDATSRERTHSFADHSGTRDDREPLTKTIKSDSAVIGGLIAVVIFILLCIAAIAVRIYQQKRLYKRNEAKRSENVDNAEAVLKSELNIQNPVKENQKEYFF", "length": 1228, "header": "tr|A0A3Q1LUC1-1|A0A3Q1LUC1_BOVIN Computationally mapped isoform of Contactin associated protein family member 4 OS=Bos taurus OX=9913 GN=CNTNAP4 PE=3 SV=2 CANONICAL=G5E5W4-1" }, "locus": { "chromosome": "18", "start_pos": 3703937, "end_pos": 3420875, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077031.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077031.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058816.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058816.2" } ] } }, { "isoform_ac": "A0A3Q1MUR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUR4/entry", "sequence": { "sequence": "MGSVTGAVLKTLLLLSTPNWNRVLAGNSYNCDDPLVSTLSQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEITAVATQGGYGSSNWVTSYLLMFSDSGRNWKQYRQEDSIWGFVGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSCLLYRFDQKSLSPIKDVISLKFKTMQSDGILLHREGQNGDHITLELRRGKLFLLINSGDAKPPSARAPVRLTLGSLLDDQHWHSVLIQRLGTQVNFTVDGHRRRFRAQGEFSSLHLDYEGNVSFSCSQPQSVPVTFLSPRSYLALPGSFGEDEISATFQFRTWNKAGLLLFTELQLVSGGLLLFLNDGKLKLHLYHPGKLPSDITAGVGLNDGQWHSVSLSAKRNYLSVVVDGQVASASPSQGPEQIYSGGIFYFGGCPDSSFGSKCKSPLGGFQGCMRLISIRHEVVDLISLQPGALGNFSDLQIDSCGITDRCLPNYCEHGGECSQSWDTFHCNCANTGYRGATCHNSIYEQSCEAYKHKGNTSGFYYIDADGSGPLEPFLLYCNMTETAWTIIQHNGSGVTRVRNTNPENPYTGFFEYVASMEQLQATINRAEHCEQELTYYCKKSRLVSKEDGAPLSWWVGRTNETQTYWGGSLPDPQKCTCGLEGNCVDSQYYCNCDADRNEWTNDTGFLSYKEHLPVTRIVITDTGRPHSEAAYKLGPLLCRGDKLFWNSASFNTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGITDFIRIELRSPAVVTFSFDVGNGPFEISVQSPTHFSDNQWHHVRVERNMKEASVRVDQLSPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGEALDLEERARVTPGVEPGCRGHCSSYGRLCHHGGMCMEKPSGFSCDCTSSAYAGPFCSDEISAYFGSGSSVIYNFQENYSLSKNSSSHAASFHGDTRLSRETIKFSFRTTRTPSLLLYLSSFYKEYLSVILAKNGDLQIRYKLNRYQEPDVVNFDFKNMADGQLHHVKINREEAVVFVEIDESMRRQVHLASGTELSAVRSLVLGRIIEHSDVDQETALAGAQGFLGCLSAVQVSHVAPLKAALQPSRPAPITVSGHVTESSCVAQAGTDATSRERTHSFADHSGTRDDREPLTKTIKSDSAVIGGLIAVVIFILLCIAAIAVRIYQQKRLYKRNEAKRSENVDNAEAVLKSELNIQNPVKENQKEYFF", "length": 1260, "header": "tr|A0A3Q1MUR4-1|G5E5W4_BOVIN Computationally mapped isoform of Contactin associated protein family member 4 OS=Bos taurus OX=9913 GN=CNTNAP4 PE=3 SV=2 CANONICAL=G5E5W4-1" }, "locus": { "chromosome": "18", "start_pos": 3703937, "end_pos": 3420875, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078139.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078139.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058666.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058666.2" } ] } }, { "isoform_ac": "G5E5W4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5W4/entry", "sequence": { "sequence": "MGSVTGAVLKTLLLLSTPNWNRVLAGNSYNCDDPLVSTLSQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEITAVATQGGYGSSNWVTSYLLMFSDSGRNWKQYRQEDSIWGFVGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSCLLYRFDQKSLSPIKDVISLKFKTMQSDGILLHREGQNGDHITLELRRGKLFLLINSGDAKPPSARAPVRLTLGSLLDDQHWHSVLIQRLGTQVNFTVDGHRRRFRAQGEFSSLHLDYEISFGGIPAPGKPVSFPHKHFHGCLENLFYDGVDIIDLAKRQDPQMIVMGNVSFSCSQPQSVPVTFLSPRSYLALPGSFGEDEISATFQFRTWNKAGLLLFTELQLVSGGLLLFLNDGKLKLHLYHPGKLPSDITAGVGLNDGQWHSVSLSAKRNYLSVVVDGQVASASPSQGPEQIYSGGIFYFGGCPDSSFGSKCKSPLGGFQGCMRLISIRHEVVDLISLQPGALGNFSDLQIDSCGITDRCLPNYCEHGGECSQSWDTFHCNCANTGYRGATCHNSIYEQSCEAYKHKGNTSGFYYIDADGSGPLEPFLLYCNMTETAWTIIQHNGSGVTRVRNTNPENPYTGFFEYVASMEQLQATINRAEHCEQELTYYCKKSRLVSKEDGAPLSWWVGRTNETQTYWGGSLPDPQKCTCGLEGNCVDSQYYCNCDADRNEWTNDTGFLSYKEHLPVTRIVITDTGRPHSEAAYKLGPLLCRGDKLFWNSASFNTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGITDFIRIELRSPAVVTFSFDVGNGPFEISVQSPTHFSDNQWHHVRVERNMKEASVRVDQLSPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGEALDLEERARVTPGVEPGCRGHCSSYGRLCHHGGMCMEKPSGFSCDCTSSAYAGPFCSDEISAYFGSGSSVIYNFQENYSLSKNSSSHAASFHGDTRLSRETIKFSFRTTRTPSLLLYLSSFYKEYLSVILAKNGSLQIRYKLNRYQEPDVVNFDFKNMADGQLHHVKINREEAVVFVEIDESMRRQVHLASGTELSAVRSLVLGRIIEHSDVDQETALAGAQGFLGCLSAVQVSHVAPLKAALQPSRPAPITVSGHVTESSCVAQAGTDATSRERTHSFADHSGTRDDREPLTKTIKSDSAVIGGLIAVVIFILLCIAAIAVRIYQQKRLYKRNEAKRSENVDNAEAVLKSELNIQNPVKENQKEYFF", "length": 1308, "header": "tr|G5E5W4-1|G5E5W4_BOVIN Isoform 1 of Contactin associated protein family member 4 OS=Bos taurus OX=9913 GN=CNTNAP4 PE=3 SV=2 CANONICAL=G5E5W4-1" }, "locus": { "chromosome": "18", "start_pos": 3703937, "end_pos": 3420875, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036878.7", "url": "https://www.ensembl.org/id/ENSBTAT00000036878.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036729.5", "url": "https://www.ensembl.org/id/ENSBTAP00000036729.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 951, "start_aa": "Thr", "end_pos": 951, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr951", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:536775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536775", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y841-1", "protein_name": "Contactin associated protein family member 4", "gene_name": "CNTNAP4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDSVTEIFLKLLFFMSVHNRSMVVTGNTYNCDDPLVSTLPQSSFSSSSELSSSHSPGFAKLNRREGAGGWSPLVSNKYQWLQIDLGERTEITAVATQGGYGSSDWVTNYLLMFSDSGRNWKQYRQEESILAISGNTNADSVVYYKLQHSIKARFLRFVPLDWNPNGRIGMRIEVYGCTYKSEVIGLDGKSCLIYTFKQEPMSALKDVISMKFKAMQSDGILLHREGKNGDHIILELVKGKLSLLINLGGYKTHSSSTQINISLGSLLDDQHWHSVLIEHFNNQVNFTVDKHTHHFHAKEVFNYLDLDYELSFGGIPVSEKSGTLSQRNFHGCFENIYYNGVNVIDLARRRKSQISFVGNMSFLCLEPKVVPVTFLSSRSYLALPGISGQEVAISFQFRTWNSEGFLVSSKVKQASGGFFLYLSDGKVKISIQKPGKLLTDLTAGVGLNNGLWHSVSFSAKRNRISLIVDNDMLSSAHASIPLQIYSGDTLYFGGCPNNGNYSECKSSFGGFQGCMQLISIGNEAVDMISVQQNIFGNFSDLQIDLCGIMDRCLPNYCEHGGKCSQSWNNFYCNCNNTGYKGATCHYPIYEKSCEAYKHRGKNSGFYNIDSDGSGPLGPFLVYCNMTDTTWTIIQHNNTNLTRIKSANRENPHAAFFKYSASLNQLQGTINHAEHCEQEISYHCKKSRLLDKPDGLPLSWWIGRTNEIQTYWGGSLPAVQKCACGLEGSCIDSQHYCNCNADRNEWTSDIGFLSYKEHLPVTEIVVTDTDRPNSEAAFKLGPLLCRGDRAFWNSASFNTETSYLHFPTLHGEFSTDVSFFFKTTASAGMFLENLGIQDFIRIELYSPYEVIFSFDVGNGPNEVKVQSLTFLNDNQWHYVKAERNIKEASLQVDKIPQKSHAAPPDGHFRLQLNSQLFVGGTASRQKGFLGCIRSLQLNGIALDLEERAKITPGVEPGCPGHCSSYGNLCDNGGKCREKYSGFTCDCTFSAYAGPFCKKEISAYFGTGTSVIYSFQENYTFAKNSSSHASAFYADMTLNRETITFAFRTTRTPSLLLYISSFYKEYLSVILSRNGSLQIRYKLDSHQDPDVCSINFKSMADGQLQHVKIDREREILFVEVNQNERMKFILSSGTEFNAIRSLILGKILENSDVDEETMKANSQGFIGCLSSVQFNHISPLKAALQHSSSAPIIVKGRVIESNCGTLTGLDSTLSETTHSFADHSGPIDEREPLANGISSDSAVIGGVIAVVIFILLCITAIAIHIYRKKSRYSKNEKKGSENEDSAESALKSELSIQNTASENQKEYFF", "length": 1307 }, "evidence": [ { "id": "G5E5W4", "url": "https://omabrowser.org/oma/group/G5E5W4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q99P47-1", "protein_name": "Contactin-associated protein-like 4", "gene_name": "Cntnap4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNMGSVAGAVLKMLLLLSTQNWNRVEAGNSYDCDEPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTSVATQGGYGSSNWVTSYLLMFSDSGRNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSVVIDLDGKSSLLYRFDQNSLSPIRDIISLKFKTMESDGILLHRAGPAGDHITLELRRGKLFLLINSGDARLTSSSTLINLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRRHFHAQGEFNYLDLDYEISFGGISAPAKSVSLPYKHFHGCLENLFYNGVDVIGLVKEHSPQIITMGNASFSCSQPQSMPLTFLSPRSYLVLPASTKEEAISASFQFRTWNKAGLLLFSELQLVSGSLLLLLSDGKLKLTLYQPGKSPSDITAGAGLGDGQWHSVSLSAKRNHLSVVVDGHISPASPWLGPEQVNSGGVFYFGGCPDKGFGSKCKSPLGGFQGCMRLISINNKMVDLIAVQQGALGNFSDLQIDSCGISDRCLPNSCEHGGECSQSWSTFHCNCTNTGYTGATCHSSVYEQSCEAYKHQGNASGFYYIDSDGSGPLQPFLLYCNMTETAWTVMQHNGSDLMRVRNTHSENAHTGVFEYTASMEQLQAAINRAEHCQQELVYYCKKSRLVNQQDGSPRSWWVGRTNETQTYWGGSLPVHQKCTCGLEGNCIDAQYHCNCDADLNEWTNDTGFLSYKEHLPVTKIVITDTGRPHSEAAYKLGPLLCRGDRPFWNAASFNTEASYLHFPTFHGELSADVSFFFKTTALSGVFLENLGITDFIRIELRSPTTVTFSFDVGNGPFELSVHSPTHFNDNQWHHVRVERNMKEASLRVDELPPKIQAAPTDGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMALDLEERATVTPGVQPGCRGHCGSYGKLCRHGGKCREKPSGFFCDCSSSAYAGPFCSKEISAYFGSGSSVIYNFQENYSLSKNSSFHAASFHGDMKLSREMIKFSFRTTRAPSLLLHMSSFYKEYLSIIIAKNGSLQIRYKLNKYHEPDVISFDLKSMADGQLHHIKINREEGMVFVEIDENTRRQTYLSSGTEFSAVKSLVLGRMLEYSDVDQETALAAAHGFTGCLSAVQFSHIAPLKAALQPGPPAPVTVTGHVTESSCVAPSGTDATSRERTHSFADHSGTMDDREPLTHAIKSDSAVIGGLIAVVIFILLCVSAIAVRIYQQKRLYKRNEAKRSENVDSAEAVLKSELHIQNAVGENQKEYFF", "length": 1310 }, "evidence": [ { "id": "G5E5W4", "url": "https://omabrowser.org/oma/group/G5E5W4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C0A0-1", "protein_name": "Contactin-associated protein-like 4", "gene_name": "CNTNAP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSENVDSAEAVLKSELNIQNAVNENQKEYFF", "length": 1308 }, "evidence": [ { "id": "G5E5W4", "url": "https://omabrowser.org/oma/group/G5E5W4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E5W4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E5W4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "G5E5W4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G5E5W4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "G5E5W4", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1023, "end_pos": 1025, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1073, "end_pos": 1075, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 549, "end_pos": 586, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 177, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 585, "end_pos": 640, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5W4" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 183, "end_pos": 364, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 951 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1017, "end_pos": 1019 }, { "start_pos": 1023, "end_pos": 1025 }, { "start_pos": 1073, "end_pos": 1075 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 602, "end_pos": 604 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 637, "end_pos": 639 }, { "start_pos": 706, "end_pos": 708 }, { "start_pos": 748, "end_pos": 750 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q05B89-1", "uniprot_ac": "Q05B89", "uniprot_id": "NIF3L_BOVIN", "mass": { "chemical_mass": 41906.0, "monoisotopic_mass": 41906.0 }, "refseq": { "ac": "NP_001073718", "name": "NIF3-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073718" }, "gene_names": [ { "name": "NIF3L1", "type": "recommended", "evidence": [ { "id": "Q05B89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ] }, { "name": "NIF3L1", "type": "synonym", "evidence": [ { "id": "NP_001073718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073718" } ] } ], "protein_names": [ { "name": "NIF3-like protein 1", "type": "recommended", "evidence": [ { "id": "Q05B89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B89/entry#names_and_taxonomy" } ] }, { "name": "GTP cyclohydrolase I", "type": "synonym", "evidence": [ { "id": "NP_001073718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073718" } ] }, { "name": "NIF3 NGG1 interacting factor 3-like 1", "type": "synonym", "evidence": [ { "id": "NP_001073718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073718" } ] }, { "name": "NIF3-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001073718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073718" } ] }, { "name": "putative GTP cyclohydrolase 1 type 2 NIF3L1", "type": "synonym", "evidence": [ { "id": "NP_001073718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073718" } ] } ], "function": [ { "annotation": "May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM63", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM63#function" }, { "database": "UniProtKB", "id": "ARBA00059551", "url": "https://www.uniprot.org/uniprotkb/ARBA00059551#function" }, { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89#function" }, { "database": "UniProtKB", "id": "Q9EQ80", "url": "https://www.uniprot.org/uniprotkb/Q9EQ80#function" }, { "database": "UniProtKB", "id": "A0AAA9SWN3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWN3#function" }, { "database": "UniProtKB", "id": "PIRNR037490", "url": "https://www.uniprot.org/uniprotkb/PIRNR037490#function" }, { "database": "UniProtKB", "id": "A0AAA9T3W1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W1#function" }, { "database": "UniProtKB", "id": "A0ABI0P0T3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0T3#function" }, { "database": "UniProtKB", "id": "A0ABI0NM48", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM48#function" }, { "database": "UniProtKB", "id": "A0A3Q1LG04", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG04#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NIF3L1", "url": "https://www.uniprot.org/uniprotkb/Q05B89", "locus": { "chromosome": "2", "start_pos": 89548724, "end_pos": 89531065, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018282", "url": "https://www.ensembl.org/id/ENSBTAG00000018282" } ] } } ], "crossref": [ { "id": "Q05B89", "url": "https://alphafold.ebi.ac.uk/entry/Q05B89", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018282", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018282", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509473", "url": "https://www.ncbi.nlm.nih.gov/gene/509473", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509473", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509473", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KYHEFFD", "url": "https://omabrowser.org/oma/group/KYHEFFD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LG04", "url": "https://www.orthodb.org/?gene=A0A3Q1LG04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LM63", "url": "https://www.orthodb.org/?gene=A0A3Q1LM63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q05B89", "url": "https://www.orthodb.org/?gene=Q05B89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13799:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13799:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001073718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LG04", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LG04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM63", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM63-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWN3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3W1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM48", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM48-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0T3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0T3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B89-1", "url": "https://www.uniprot.org/uniprotkb/Q05B89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLESPVKVVALCAGSGSSVLQGTDADLYLTGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI", "length": 377, "header": "sp|Q05B89-1|NIF3L_BOVIN Isoform 1 of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=2 SV=1 CANONICAL=Q05B89-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LG04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG04/entry", "sequence": { "sequence": "MLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI", "length": 349, "header": "tr|A0A3Q1LG04-1|NIF3L_BOVIN Computationally mapped isoform of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=2 SV=3 CANONICAL=Q05B89-1" }, "locus": { "chromosome": "2", "start_pos": 89547720, "end_pos": 89533433, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067436.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067436.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057237.3", "url": "https://www.ensembl.org/id/ENSBTAP00000057237.3" } ] } }, { "isoform_ac": "A0A3Q1LM63-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM63/entry", "sequence": { "sequence": "MFGFFLVYSVLPDFCMLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLESPVKVVALCAGSGSSVLQGTDADLYLTGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI", "length": 392, "header": "tr|A0A3Q1LM63-1|NIF3L_BOVIN Computationally mapped isoform of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=2 SV=2 CANONICAL=Q05B89-1" }, "locus": { "chromosome": "2", "start_pos": 89547720, "end_pos": 89533292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070059.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070059.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060946.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060946.2" } ] } }, { "isoform_ac": "A0AAA9SWN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWN3/entry", "sequence": { "sequence": "MGRARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLESPVKVVALCAGSGSSVLQGTDADLYLTGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI", "length": 368, "header": "tr|A0AAA9SWN3-1|NIF3L_BOVIN Computationally mapped isoform of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=2 SV=1 CANONICAL=Q05B89-1" }, "locus": { "chromosome": "2", "start_pos": 89547720, "end_pos": 89531273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130969.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130969.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088473.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088473.1" } ] } }, { "isoform_ac": "A0AAA9T3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3W1/entry", "sequence": { "sequence": "MIEPIFELRYSVLPDFCMLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLESPVKVVALCAGSGSSVLQGTDADLYLTGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI", "length": 394, "header": "tr|A0AAA9T3W1-1|NIF3L_BOVIN Computationally mapped isoform of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=2 SV=1 CANONICAL=Q05B89-1" }, "locus": { "chromosome": "2", "start_pos": 89547720, "end_pos": 89532847, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130626.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130626.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091338.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091338.1" } ] } }, { "isoform_ac": "A0ABI0NM48-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM48/entry", "sequence": { "sequence": "MAPRYSVLPDFCMLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLESPVKVVALCAGSGSSVLQGTDADLYLTGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI", "length": 389, "header": "tr|A0ABI0NM48-1|A0ABI0NM48_BOVIN Computationally mapped isoform of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=3 SV=1 CANONICAL=Q05B89-1" }, "locus": { "chromosome": "2", "start_pos": 89547720, "end_pos": 89531878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146930.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146930.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106475.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106475.1" } ] } }, { "isoform_ac": "A0ABI0P0T3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0T3/entry", "sequence": { "sequence": "MLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKSPQSKSWLCALVLGAASCRGQMPTFISQVRCPTMMFWMLLPKE", "length": 285, "header": "tr|A0ABI0P0T3-1|A0ABI0P0T3_BOVIN Computationally mapped isoform of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=3 SV=1 CANONICAL=Q05B89-1" }, "locus": { "chromosome": "2", "start_pos": 89547583, "end_pos": 89533433, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149783.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149783.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106251.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106251.1" } ] } }, { "isoform_ac": "Q05B89-1", "url": "https://www.uniprot.org/uniprotkb/Q05B89/entry#Q05B89-1", "sequence": { "sequence": "MLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLESPVKVVALCAGSGSSVLQGTDADLYLTGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI", "length": 377, "header": "sp|Q05B89-1|NIF3L_BOVIN Isoform 1 of NIF3-like protein 1 OS=Bos taurus OX=9913 GN=NIF3L1 PE=2 SV=1 CANONICAL=Q05B89-1" }, "locus": { "chromosome": "2", "start_pos": 89547720, "end_pos": 89533433, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116499.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116499.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083624.2", "url": "https://www.ensembl.org/id/ENSBTAP00000083624.2" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 255, "end_pos": 255, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "site_lbl": "Thr255" }, { "start_pos": 259, "end_pos": 259, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "site_lbl": "Ser259" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509473", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509473", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B238-1", "protein_name": "NIF3-like protein 1", "gene_name": "NIF3L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLLSRVRLASTTVRFVHSLICSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVSTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKSWKERLVIRALENRVGIYSPHTAYDAAPQGVNHWLAKGLGVCTSRPIHPSKAPDYPTEGTHKVEFSVTNDEDLDKVISAVKGIPGVSVTSFSARTDDEEQTQLNLNCTQQALMQVVAFLSQNRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLETMIERIKKHLKLSHVRLALGVGKTRESPVKVVALCAGSGSSVLQGTEADLYLTGEMSHHDVLDAASQGINVILCEHSNTERGFLSDLRDMLAAHLENKINIILSETDRDPLHVV", "length": 377 }, "evidence": [ { "id": "Q05B89", "url": "https://omabrowser.org/oma/group/Q05B89/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MGI3-1", "protein_name": "NIF3-like protein 1", "gene_name": "Nif3l1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSSAHLLPTSVRLAPSWICRSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRAMKHITWKTWKERLVIRALENRVAIYSPHTAYDAAPQGVNNWLAKGLGTCSTRPIHPSRAPNYPTEGAHRLEFSVNHTQDLDKVMSAVKGIGDVSVTSFAARCDDEEQTRISLNCTQKALMQVLAFLSQNRQLYQKTEILSLEKPLLLDTGMGRLCTLDESVSLATMIERVKGYLKLSHLRLALGVGKTLESPVKVVALCAGSGGSVLQGVEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSDLQQMLGVHLENKINIILSETDRDPLHVV", "length": 376 }, "evidence": [ { "id": "Q05B89", "url": "https://omabrowser.org/oma/group/Q05B89/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4V7D6-1", "protein_name": "NIF3-like protein 1", "gene_name": "Nif3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSSAHVVPTSVRRAPSWICSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWKTWKERLVIRALENRVAIYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSKAPNYPTEGTHRLEFSANHSQDLDKVMSAVKGVGGVSVTSFPARCDGEEQTRVSLNCTQKALMQVLAFLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIERIKRHLKLPHLRLALGVGRTLESPVKVVALCAGSGGSVLQGVEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSDLQEMLGVHLENKINIILSETDRDPLRVV", "length": 376 }, "evidence": [ { "id": "Q05B89", "url": "https://omabrowser.org/oma/group/Q05B89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQ80-1", "protein_name": "NIF3-like protein 1", "gene_name": "Nif3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSAHLVPTSVQRAQSWICRSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMDEALQKKADFILSYHPPIFRPMKHITWKTWKECLVIRALENRVAVYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSRAPDYPTEGAHRLEFSVNRSQDLDKVMSTLRGVGGVSVTSFPARCDGEEQTRISLNCTQKTLMQVLAFLSQDRQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLAIMIERIKTHLKLSHLRLALGVGRTLESQVKVVALCAGSGGSVLQGVEADLYLTGEMSHHDVLDAASKGINVILCEHSNTERGFLSELQEMLGVHFENKINIILSETDRDPLRVV", "length": 376 }, "evidence": [ { "id": "Q05B89", "url": "https://omabrowser.org/oma/group/Q05B89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZT8-1", "protein_name": "NIF3-like protein 1", "gene_name": "NIF3L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSCVRPVPTTVRFVDSLICNSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEVLQKKADLILSYHPPIFRPMKRITWNTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGACTSRPIHPSKAPNYPTEGNHRVEFNVNYTQDLDKVMSAVKGIDGVSVTSFSARTGNEEQTRINLNCTQKALMQVVDFLSRNKQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIDRIKRHLKLSHIRLALGVGRTLESQVKVVALCAGSGSSVLQGVEADLYLTGEMSHHDTLDAASQGINVILCEHSNTERGFLSDLRDMLDSHLENKINIILSETDRDPLQVV", "length": 377 }, "evidence": [ { "id": "Q05B89", "url": "https://omabrowser.org/oma/group/Q05B89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "Q05B89", "url": "https://www.uniprot.org/uniprotkb/Q05B89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q05B89-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 377, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q05B89-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q05B89" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 105, "amino_acid": "Trp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 105, "end_pos": 105, "start_aa": "Trp", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 108, "amino_acid": "Trp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 108, "end_pos": 108, "start_aa": "Trp", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 110, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 110, "end_pos": 110, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 122, "amino_acid": "Gly", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 122, "end_pos": 122, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 131, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 131, "end_pos": 131, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 143, "amino_acid": "Lys", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 143, "end_pos": 143, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 146, "amino_acid": "Gly", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 146, "end_pos": 146, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 148, "amino_acid": "Cys", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 148, "end_pos": 148, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 311, "amino_acid": "Ala", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 311, "end_pos": 311, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 315, "amino_acid": "Leu", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 315, "end_pos": 315, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 330, "amino_acid": "Gln", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 330, "end_pos": 330, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 334, "amino_acid": "Val", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 334, "end_pos": 334, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 351, "amino_acid": "Arg", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 351, "end_pos": 351, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 354, "amino_acid": "Leu", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 354, "end_pos": 354, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 355, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 355, "end_pos": 355, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 356, "amino_acid": "Ala", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 356, "end_pos": 356, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 358, "amino_acid": "Leu", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 358, "end_pos": 358, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 360, "amino_acid": "Asn", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 360, "end_pos": 360, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 84, "amino_acid": "Lys", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 84, "end_pos": 84, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR602678-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602678-1" } ], "binding_site_uniprot": 93, "amino_acid": "His", "chebi_lig_id": "CHEBI:60240", "ligand": "divalent metal cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 93, "end_pos": 93, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 255, 259 ], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "O97790-1", "uniprot_ac": "O97790", "uniprot_id": "TBCD1_BOVIN", "mass": { "chemical_mass": 132097.0, "monoisotopic_mass": 132097.0 }, "refseq": { "ac": "NP_001159996", "name": "TBC1 domain family member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159996" }, "gene_names": [ { "name": "TBC1D1", "type": "recommended", "evidence": [ { "id": "O97790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97790" } ] }, { "name": "LYN", "type": "synonym", "evidence": [ { "id": "O97790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97790" } ] }, { "name": "TBC1D1", "type": "synonym", "evidence": [ { "id": "NP_001159996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159996" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 1", "type": "recommended", "evidence": [ { "id": "O97790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97790/entry#names_and_taxonomy" } ] }, { "name": "Lyncein", "type": "synonym", "evidence": [ { "id": "O97790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97790/entry#names_and_taxonomy" } ] }, { "name": "TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1", "type": "synonym", "evidence": [ { "id": "NP_001159996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159996" } ] }, { "name": "TBC1 domain family member 1", "type": "synonym", "evidence": [ { "id": "NP_001159996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159996" } ] }, { "name": "lyncein", "type": "synonym", "evidence": [ { "id": "NP_001159996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159996" } ] } ], "function": [ { "annotation": "May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790#function" }, { "database": "UniProtKB", "id": "A0A3Q1M1P0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P0#function" }, { "database": "UniProtKB", "id": "ARBA00055418", "url": "https://www.uniprot.org/uniprotkb/ARBA00055418#function" }, { "database": "UniProtKB", "id": "A0A3Q1M087", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M087#function" }, { "database": "UniProtKB", "id": "A0A3Q1MAG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAG3#function" }, { "database": "UniProtKB", "id": "A0A3Q1MSW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSW4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TBC1D1", "url": "https://www.uniprot.org/uniprotkb/O97790", "locus": { "chromosome": "6", "start_pos": 57429961, "end_pos": 57203610, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013699", "url": "https://www.ensembl.org/id/ENSBTAG00000013699" } ] } } ], "crossref": [ { "id": "O97790", "url": "https://alphafold.ebi.ac.uk/entry/O97790", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013699", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00934", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00934", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "282704", "url": "https://www.ncbi.nlm.nih.gov/gene/282704", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:282704", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282704", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETPHEQK", "url": "https://omabrowser.org/oma/group/ETPHEQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M087", "url": "https://www.orthodb.org/?gene=A0A3Q1M087", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1P0", "url": "https://www.orthodb.org/?gene=A0A3Q1M1P0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAG3", "url": "https://www.orthodb.org/?gene=A0A3Q1MAG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MSW4", "url": "https://www.orthodb.org/?gene=A0A3Q1MSW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "O97790", "url": "https://www.orthodb.org/?gene=O97790", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11830", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11830", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001159996", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M087", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M087", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M087-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M087-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1P0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O97790-1", "url": "https://www.uniprot.org/uniprotkb/O97790-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQSSKKEPGTKPVRLCVSPSGLRCEPEPGKSQQWDPLICSSIFECKPQRVHKLIHNSHDPSYFACLIKNDAANQQSICYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVAVAHRKAPPALIDECIEGFSHVSGGFSSDQSRSALQPPGDGERGPRPMRKSFSQPGLRSLAFRKEFQDAGLRSSSFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALQKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKVHIHIGEIKQTSQIAAENIGSELPSSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSASLDLDSSVSSMFSNTSKEPSGYEKEALPISESCFRLLGSSDDLSSDSESQLTEEPALLSPKQGFRRRANTLSHVPVECQEPPQLVRGSPGVSQRKLVRYHSVSTETPHERKDFESKADHISDASRTPVKTRRHSWRQQIFLRVATPQKACESPKRYEDYSELGELPPRSPLEPVCEDGPFGPVPEEKKRTSHELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKILSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHPFPCKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFETDISKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATVEKLLTSESKLKQATLALELERSALLQTVEQLRRQTAELGSQESDPTLPKPSGD", "length": 1165, "header": "sp|O97790-1|TBCD1_BOVIN Isoform 1 of TBC1 domain family member 1 OS=Bos taurus OX=9913 GN=TBC1D1 PE=2 SV=2 CANONICAL=O97790-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M087-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M087/entry", "sequence": { "sequence": "MSHVAEISRLAGTEGSFSTAPSLVSTFEFSDYKKTTFDYIKVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVAVAHRKAPPALIDECIEGFSHVSGGFSSDQSRSALQPPGDGERGPRPMRKSFSQPGLRSLAFRKEFQDAGLRSSSFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALQKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKVHIHIGEIKQTSQIAAENIGSELPSSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSASLDLDSSVSSMFSNTSKEPSGYEKEALPISESCFRLLGSSDDLSSDSESQLTEEPALLSPKQGFRRRANTLSHVPVECQEPPQLVRGSPGVSQRKLVRYHSVSTETPHERKDFESKADHISDASRTPVKTRRHSWRQQIFLRVATPQKACESPKRYEDYSELGELPPRSPLEPVCEDGPFGPVPEEKKRTSHELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKILSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHPFPCKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFETDISKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATVEKLLTSESKLKQATLALELERSALLQTVEQLRRQTAELGSQESDPTLPKPSGD", "length": 1067, "header": "tr|A0A3Q1M087-1|TBCD1_BOVIN Computationally mapped isoform of TBC1 domain family member 1 OS=Bos taurus OX=9913 GN=TBC1D1 PE=2 SV=2 CANONICAL=O97790-1" }, "locus": { "chromosome": "6", "start_pos": 57428337, "end_pos": 57281784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076984.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076984.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061372.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061372.2" } ] } }, { "isoform_ac": "A0A3Q1M1P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P0/entry", "sequence": { "sequence": "MEPITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQSSKKEPGTKPVRLCVSPSGLRCEPEPGKSQQWDPLICSSIFECKPQRVHKLIHNSHDPSYFACLIKNDAANQQSICYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVAVAHRKAPPALIDECIEGFSHVSGGFSSDQSRSALQPPGDGERGPRPMRKSFSQPGLRSLAFRKEFQDAGLRSSSFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALQKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKVHIHIGEIKQTSQIAAENIGSELPSSATRFRLDMLKNKAKRSLTESLESILSRVMPCDTSDLLSVCYQEPSGYEKEALPISESCFRLLGSSDDLSSDSESQLTEEPALLSPKQGFRRRANTLSHVPVECQEPPQLVRGSPGVSQRKLVRYHSVSTETPHERKDFESKADHISDASRTPVKTRRHSWRQQIFLRVATPQKACESPKRYEDYSELGELPPRSPLEPVCEDGPFGPVPEEKKRTSHELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKILSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHPFPCKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFETDISKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATVEKLLTSESKLKQATLALELERSALLQTVEQLRRQTAELGSQESDPTLPKPSGD", "length": 1151, "header": "tr|A0A3Q1M1P0-1|TBCD1_BOVIN Computationally mapped isoform of TBC1 domain family member 1 OS=Bos taurus OX=9913 GN=TBC1D1 PE=2 SV=1 CANONICAL=O97790-1" }, "locus": { "chromosome": "6", "start_pos": 57428337, "end_pos": 57214173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068505.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068505.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067275.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067275.1" } ] } }, { "isoform_ac": "A0A3Q1MAG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAG3/entry", "sequence": { "sequence": "MKYAVHGCGEHDVAPVVAGPVHPNHCAVLGLVTQSCPTLCYPTYVCSLPGSSVQGILQVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVAVAHRKAPPALIDECIEGFSHVSGGFSSDQSRSALQPPGDGERGPRPMRKSFSQPGLRSLAFRKEFQDAGLRSSSFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALQKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKVHIHIGEIKQTSQIAAENIGSELPSSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSASLDLDSSVSSMFSNTSKEPSGYEKEALPISESCFRLLGSSDDLSSDSESQLTEEPALLSPKQGFRRRANTLSHVPVECQEPPQLVRGSPGVSQRKLVSGNCPPVGESQSPSGQSSAPAPPPRLNPSASSPNFFKYLKHNPSGEQSGNAVPKRDFESKADHISDASRTPVKTRRHSWRQQIFLRVATPQKACESPKRYEDYSELGELPPRSPLEPVCEDGPFGPVPEEKKRTSHELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKILSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHPFPCKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFETDISKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATVEKLLTSESKLKQATLALELERSALLQTVEQLRRQTAELGSQESDPTLPKPSGD", "length": 1125, "header": "tr|A0A3Q1MAG3-1|TBCD1_BOVIN Computationally mapped isoform of TBC1 domain family member 1 OS=Bos taurus OX=9913 GN=TBC1D1 PE=2 SV=2 CANONICAL=O97790-1" }, "locus": { "chromosome": "6", "start_pos": 57428337, "end_pos": 57316285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076798.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076798.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071005.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071005.2" } ] } }, { "isoform_ac": "A0A3Q1MSW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSW4/entry", "sequence": { "sequence": "MEPITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQSSKKEPGTKPVRLCVSPSGLRCEPEPGKSQQWDPLICSSIFECKPQRVHKLIHNSHDPSYFACLIKNDAANQQSICYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVAVAHRKAPPALIDECIEGFSHVSGGFSSDQSRSALQPPGDGERGPRPMRKSFSQPGLRSLAFRKEFQDAGLRSSSFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALQKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKVHIHIGEIKQTSQIAAENIGSELPSSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSASLDLDSSVSSMFSNTSKEPSGYEKEALPISESCFRLLGSSDDLSSDSESQLTEEPALLSPKQGFRRRANTLSHVPVECQEPPQLVRGSPGVSQRKLVRYHSVSTETPHERNGNCPPVGESQSPSGQSSAPAPPPRLNPSASSPNFFKYLKHNPSGEQSGNAVPKSISYRNALRKKLHSSSSVPNFLKFLAPVDENNTSDFMNTQRDFESKADHISDASRTPVKTRRHSWRQQIFLRVATPQKACESPKRYEDYSELGELPPRSPLEPVCEDGPFGPVPEEKKRTSHELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKILSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHPFPCKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFETDISKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATVEKLLTSESKLKQATLALELERSALLQTVEQLRRQTAELGSQESDPTLPKPSGD", "length": 1259, "header": "tr|A0A3Q1MSW4-1|TBCD1_BOVIN Computationally mapped isoform of TBC1 domain family member 1 OS=Bos taurus OX=9913 GN=TBC1D1 PE=2 SV=2 CANONICAL=O97790-1" }, "locus": { "chromosome": "6", "start_pos": 57428337, "end_pos": 57214173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083632.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083632.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073240.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073240.2" } ] } }, { "isoform_ac": "O97790-1", "url": "https://www.uniprot.org/uniprotkb/O97790/entry#O97790-1", "sequence": { "sequence": "MEPITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQSSKKEPGTKPVRLCVSPSGLRCEPEPGKSQQWDPLICSSIFECKPQRVHKLIHNSHDPSYFACLIKNDAANQQSICYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVAVAHRKAPPALIDECIEGFSHVSGGFSSDQSRSALQPPGDGERGPRPMRKSFSQPGLRSLAFRKEFQDAGLRSSSFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALQKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKVHIHIGEIKQTSQIAAENIGSELPSSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSASLDLDSSVSSMFSNTSKEPSGYEKEALPISESCFRLLGSSDDLSSDSESQLTEEPALLSPKQGFRRRANTLSHVPVECQEPPQLVRGSPGVSQRKLVRYHSVSTETPHERKDFESKADHISDASRTPVKTRRHSWRQQIFLRVATPQKACESPKRYEDYSELGELPPRSPLEPVCEDGPFGPVPEEKKRTSHELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKILSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHPFPCKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYYSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFETDISKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATVEKLLTSESKLKQATLALELERSALLQTVEQLRRQTAELGSQESDPTLPKPSGD", "length": 1165, "header": "sp|O97790-1|TBCD1_BOVIN Isoform 1 of TBC1 domain family member 1 OS=Bos taurus OX=9913 GN=TBC1D1 PE=2 SV=2 CANONICAL=O97790-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 146, "end_pos": 146, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser146" }, { "start_pos": 232, "end_pos": 232, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKB/AKT1", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser232" }, { "start_pos": 234, "end_pos": 234, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by AMPK", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser234" }, { "start_pos": 500, "end_pos": 500, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser500" }, { "start_pos": 502, "end_pos": 502, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by PKB/AKT1", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Thr502" }, { "start_pos": 504, "end_pos": 504, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser504" }, { "start_pos": 522, "end_pos": 522, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser522" }, { "start_pos": 524, "end_pos": 524, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser524" }, { "start_pos": 562, "end_pos": 562, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser562" }, { "start_pos": 563, "end_pos": 563, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser563" }, { "start_pos": 567, "end_pos": 567, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser567" }, { "start_pos": 568, "end_pos": 568, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser568" }, { "start_pos": 582, "end_pos": 582, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser582" }, { "start_pos": 593, "end_pos": 593, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Thr593" }, { "start_pos": 611, "end_pos": 611, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser611" }, { "start_pos": 624, "end_pos": 624, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKB/AKT1", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser624" }, { "start_pos": 692, "end_pos": 692, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser692" }, { "start_pos": 938, "end_pos": 938, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Ser938" }, { "start_pos": 949, "end_pos": 949, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "site_lbl": "Tyr949" } ], "glycation": [], "keywords": [], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] }, { "title": "Retinal targets for calmodulin include proteins implicated in synaptic transmission.", "journal": "J. Biol. Chem.", "date": "1998", "authors": "Xu X Z, Wes P D, Chen H, Li H S, Yu M, Morgan S, Liu Y, Montell C", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "reference": [ { "type": "PubMed", "id": "9813038", "url": "https://glygen.org/publication/PubMed/9813038" } ] } ], "pathway": [ { "id": "bta:282704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282704", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZMX5-1", "protein_name": "TBC1 domain family member 1", "gene_name": "Tbc1d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQCSKKEPGMKQVRLWVSPSGLRCEPDLRKSQPWDPLICSSIFECKPQRVHKLIHNSQDPSYFACLIKEDAAHQQSLCYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSCGRRIDWDAPTGQPSAPGARPMRKSFSQPGLRSLAFRKEFQDASLRSSTFSSFDNDIENHLIGGHNVVQPTDMEENRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRECSGGGGAGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQAMIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHSHTGEPKQTLQVAAENIGSELPPSASRFRLDSLKNRAKRSLTESLESILSRGNKARGLQDHSASVDLDSSTSSTLSNTSKELSMGDKEALPISESSFKLLGSSDDLSSDSESHIAEESALLSPQQAFRRRANTLSHFPVECPAPPEPAQTSPGVSQRKLMRYHSVSTETPHERNVDHLPGGESRCCPGQPSDPPPLPPRLNPSASSPNFFKYLKHNSSGEQSGNAVPKSVSYRNALRKKLHSSSSVPNFLKFLAPVDENNTCDFKNTNRDFESKANHLGDTDGTPVKARRHSWRQQIFLRVATPQKACDSPSRYEDYSELGELPPRSPLEPVCEDGPFGPVQEEKKKTSRELRELWKKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAEQFHLKHPFPSKQQPKDVPYKELLKKLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEYEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKNTLPNLGLVQMEKTISQVFEMDIAKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANARIQSLEVTVEKLLTSESKLKQAVLTLEMERSALLQMVEELRRQMAQPSTAEPDCTRLEPTGD", "length": 1257 }, "evidence": [ { "id": "O97790", "url": "https://omabrowser.org/oma/group/O97790/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YRV2-1", "protein_name": "TBC1 domain family member 1", "gene_name": "TBC1D1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPITFKAKKYQAPSDFSASFTLQLVGSLPVHSLTTMSMLPWIVAEIRALSNTKSSKEEIGISQIRLYISPSSLRCEPDTGKIQQWDPLICSGLFEYKPQHVHKLIHNSHDPSYFACLIKDGAANQQSICYVFKADDQTKVPEIISSIRQAGKIARQEEFQNNLSDIEDPFAKKFEVLFCGRVTVAHKNAPPALIDECIEKFNHASCTKKSDSDSSSQQHETADNSGGFSFSNKFRAVFQPLMGEEEEKRPIRKSFSQPGLRSLAFKKDFQEGSHRSNSFVRSFEEDAISLNLKSQLIYGHSVVQPTDIAENRTMLFTIGQSEVYLISPDTKKVAIEKSFKEISFCSQGIRHVDHFGFICRESSENGGFHFVCYVFQCTDEALVDEIMMTLKQAFTVAAVQQTSKAQPQLCETCPLQSLHKLCEKIEGLHPSKTKLELQKHLTTLNSQEQASVFEEVKKLRPRNDQKENELIISILRNMYEEKQKNHVHVGEGKQTSQPSAENAVNEVPSSAPRFRLDMLKNKAKRSLTESFESILSRGSKTRGPLDSSSGSVDLEASVSSNLSSTNKEQPLSERETDRVPTLPPENAVKSSGSVGDLSSDPDSYAIDHSVTLPQQSFRRRANTLSHLPSESRESLVPVETSPSVPQRKLMRYHSVSTETPHKRNSSGQLARSPTLARLNPSASSPNFFKYLRHNSSGEQSGHFAQKSISYRTALRKKLHSSSSVPNFLKFLAPVDENNTSDFRSTTSDYESKHSQQAAGADSPVRTRRHSWRQQIFLRVATPQKACDSPSRYDDYTELGELPPRSPLEPVCEDGPFGPVKEERKRTSRELRELWKKAIIQQILLLRMEKENQKLQASENNLQNRRLKLDYEEITPCLKEVTLIWEKMLSTPGRSKIKFDMEKIHSAVGQGVPRHHRGEIWKFLAEQYHLKHQFPNKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGVLLLHMSEEDAFKMLKFLMFDVGLRKQYRPDMTILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMLFLQGSEAIFKVALSLLGSHKPLILQHENLETIVDFIKNTLPNLGLVQMEKTISQVFEMDIAKQLQAYEVEYHVLQDELIDSSLNDNQRLDKLEKANSSLRKQNFELLEELQVANGKIQNLEATVELLLTNEGKLKESILTLEQERTALQKAVEEMRRKIGDTNEKPLLTRQEHLDAD", "length": 1278 }, "evidence": [ { "id": "O97790", "url": "https://omabrowser.org/oma/group/O97790/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LNR0-1", "protein_name": "TBC1 domain family member 1", "gene_name": "TBC1D1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPITFTARKHPFPNEASVGFSLQLVGSLRVHSLTTMPMLPWVVAEVRRLSGQSSKKEPGTKQVRLCVSPSGLRCEPEPGKSQQWDPLICSSIFECKPQRVHKLIHNSHDPSYFACLIKDDAANQQSICYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSELDDTFAKKFEVLFCGRVAVAHRKAPPALIDECIEGFSHVCGGFSPGSVLPPPPPPGEREPGPRPMRKSFSQPGLRSLAFRKEFQDAGLRSSSFFSSFEENDIENHLMSGHSLVQPTDIEGNRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRESSGAGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQSLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKVHVHIGEIKQASQIAAENIGSELPPSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSTSLDLDSSVSSTLSSTSKEPSVCEKEALPISESAFRLLGSSDDLSSDPEGQPAEELALPSPQQGFRRRANTLSHVPAECPEPPEPARASPGPSQRKLVRYHSVSTETPHERNGDRPPVGECKSPSGQSSAPAPPPRLNPSASSPNFFKYLKHNSSGEQSGDAVPKSISYRNALRKKLHSSSSVPNFLKFLAPVDENNTSDFMTAKRDFESKANHLSDSPGTPVKTRRHSWRQQIFLRVATPQKACDSSGRYEDYSDLGELPPRSPLEPVCEDGPFGPVPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQYHLKHQFPSKQQPKDTPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMGEEEAFNMLKFLMFDMGLRKQYRPDMIILQVQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTISQVFEMDISKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLTSERKLKQATLALELERSALLQTVEQLRRRTVEQGGPEPDLTLPGPAGD", "length": 1259 }, "evidence": [ { "id": "O97790", "url": "https://omabrowser.org/oma/group/O97790/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q60949-1", "protein_name": "TBC1 domain family member 1", "gene_name": "Tbc1d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSGQCSKKEPRTKQVRLWVSPSGLRCEPDLEKSQPWDPLICSSIFECKPQRVHKLIHNSHDPSYFACLIKEDAAHRQSLCYVFKADDQTKVPEIISSIRQAGKIARQEELRCPSEFDDTFAKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSCGRRTDWEAPTGQPSAPGPRPMRKSFSQPGLRSLAFRKEFQDASLRSSTFSSFDNDIENHLIGGHNVVQPTDMEENRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRECSGGGSGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHSHTGEPKQTLQVAAENIGSDLPPSASRFRLDSLKNRAKRSLTESLESILSRGNKARGLQDHSASVDLDSSTSSTLSNTSKELSMGDKEAFPVSETSFKLLGSSDDLSSDSEGHIAEESALLSPQQAFRRRANTLSHFPVECPAPPEPAQSSPGVSQRKLMRYHSVSTETPHERNVDHLPGGESQGCPGQPSAPPPPRLNPSASSPNFFKYLKHNSSGEQSGNAVPKSVSYRNALRKKLHSSSSVPNFLKFLAPVDENNTCDFKNTNRDFESKANHLGDTDGTPVKTRRHSWRQQIFLRVATPQKACDSPSRYEDYSELGELPPRSPLEPVCEDGPFGPVQEEKRKTSRELRELWKKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAEQFHLKHPFPSKQQPKDVPYKELLKKLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLLGSHKPLILQHENLETIVDFIKNTLPNLGLVQMEKTISQVFEMDIAKQLQAYEVEYHVLQEELIESSPLSDNQRMEKLEKTNSSLRKQNLDLLEQLQVANARIQSLEATVEKLLTSESKLKQAALTLEVERSALLQMVEELRRQSARPSTPEPDCTQLEPTGD", "length": 1255 }, "evidence": [ { "id": "O97790", "url": "https://omabrowser.org/oma/group/O97790/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86TI0-1", "protein_name": "TBC1 domain family member 1", "gene_name": "TBC1D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPITFTARKHLLSNEVSVDFGLQLVGSLPVHSLTTMPMLPWVVAEVRRLSRQSTRKEPVTKQVRLCVSPSGLRCEPEPGRSQQWDPLIYSSIFECKPQRVHKLIHNSHDPSYFACLIKEDAVHRQSICYVFKADDQTKVPEIISSIRQAGKIARQEELHCPSEFDDTFSKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSGSRGSESPRPNPPHAAPTGSQEPVRRPMRKSFSQPGLRSLAFRKELQDGGLRSSGFFSSFEESDIENHLISGHNIVQPTDIEENRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRESSGGGGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQSLHKLCERIEGMNSSKTKLELQKHLTTLTNQEQATIFEEVQKLRPRNEQRENELIISFLRCLYEEKQKEHIHIGEMKQTSQMAAENIGSELPPSATRFRLDMLKNKAKRSLTESLESILSRGNKARGLQEHSISVDLDSSLSSTLSNTSKEPSVCEKEALPISESSFKLLGSSEDLSSDSESHLPEEPAPLSPQQAFRRRANTLSHFPIECQEPPQPARGSPGVSQRKLMRYHSVSTETPHERKDFESKANHLGDSGGTPVKTRRHSWRQQIFLRVATPQKACDSSSRYEDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQMEKTINQVFEMDIAKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQAMLTLELERSALLQTVEELRRRSAEPSDREPECTQPEPTGD", "length": 1168 }, "evidence": [ { "id": "O97790", "url": "https://omabrowser.org/oma/group/O97790/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O97790", "url": "https://www.uniprot.org/uniprotkb/O97790" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1084, "end_pos": 1086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-O97790-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1165, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-O97790-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/O97790" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "O97790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97790" }, { "id": "PRU00148", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00148" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000255", "start_pos": 243, "end_pos": 401, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "O97790", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97790" }, { "id": "PRU00163", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00163" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000255", "start_pos": 797, "end_pos": 991, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 146, 232, 234, 500, 502, 504, 522, 524, 562, 563, 567, 568, 582, 593, 611, 624, 692, 938, 949 ], "sequon_annotation_sites": [ { "start_pos": 1084, "end_pos": 1086 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 19 }, { "field": "total_sites", "count": 19 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08D99-1", "uniprot_ac": "Q08D99", "uniprot_id": "TM41A_BOVIN", "mass": { "chemical_mass": 29577.0, "monoisotopic_mass": 29577.0 }, "refseq": { "ac": "NP_001068668", "name": "transmembrane protein 41A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068668" }, "gene_names": [ { "name": "TMEM41A", "type": "recommended", "evidence": [ { "id": "Q08D99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08D99" } ] }, { "name": "TMEM41A", "type": "synonym", "evidence": [ { "id": "NP_001068668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068668" } ] } ], "protein_names": [ { "name": "Transmembrane protein 41A", "type": "recommended", "evidence": [ { "id": "Q08D99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08D99/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 41A precursor", "type": "synonym", "evidence": [ { "id": "NP_001068668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068668" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08D99", "url": "https://www.uniprot.org/uniprotkb/Q08D99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM41A", "url": "https://www.uniprot.org/uniprotkb/Q08D99", "locus": { "chromosome": "1", "start_pos": 81705117, "end_pos": 81696424, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017115", "url": "https://www.ensembl.org/id/ENSBTAG00000017115" } ] } } ], "crossref": [ { "id": "Q08D99", "url": "https://alphafold.ebi.ac.uk/entry/Q08D99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017115", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017115", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505368", "url": "https://www.ncbi.nlm.nih.gov/gene/505368", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505368", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505368", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DNRDCLF", "url": "https://omabrowser.org/oma/group/DNRDCLF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1F1", "url": "https://www.orthodb.org/?gene=A0A3Q1M1F1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q08D99", "url": "https://www.orthodb.org/?gene=Q08D99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43220:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43220:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001068668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1F1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIQ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08D99", "url": "https://www.uniprot.org/uniprotkb/Q08D99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08D99-1", "url": "https://www.uniprot.org/uniprotkb/Q08D99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSLLGLLLVFAGSTFALYLLSTRLPRASTLVSAEESGDRSLWFPSDLAELRELSEVLREYRKEHQVYVFLLFCSAYLYKQSFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLLSSVFGKQLVVFYFPDKVALLQKKVEENRNGLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETAFKLLAIALVALVPGTLIKKFSQKDLRLKETSNTHSLNSRKVT", "length": 264, "header": "sp|Q08D99-1|TM41A_BOVIN Isoform 1 of Transmembrane protein 41A OS=Bos taurus OX=9913 GN=TMEM41A PE=2 SV=1 CANONICAL=Q08D99-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1F1/entry", "sequence": { "sequence": "SCWSTSAPPIGSPLGDVPVAFPGPGLTPICIPPSPRCGPRSRSLWFPSDLAELRELSEVLREYRKEHQVYVFLLFCSAYLYKQSFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLLSSVFGKQLVVFYFPDKVALLQKKVEENRNGLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETAFKLLAIALVALVPGTLIKKFSQKDLRLKETSNTHSLNSRKVT", "length": 266, "header": "tr|A0A3Q1M1F1-1|TM41A_BOVIN Computationally mapped isoform of Transmembrane protein 41A OS=Bos taurus OX=9913 GN=TMEM41A PE=2 SV=1 CANONICAL=Q08D99-1" }, "locus": { "chromosome": "1", "start_pos": 81704399, "end_pos": 81696932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080192.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080192.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061884.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061884.1" } ] } }, { "isoform_ac": "A0AAA9TQB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQB8/entry", "sequence": { "sequence": "MHSLLGLLLVFAGSTFALYLLSTRLPRASTLVSAEESGDRSLWFPSDLAELRELSEVLREYRKEHQVYVFLLFCSAYLYKQSFAIPGSSFLV", "length": 92, "header": "tr|A0AAA9TQB8-1|TM41A_BOVIN Computationally mapped isoform of Transmembrane protein 41A OS=Bos taurus OX=9913 GN=TMEM41A PE=2 SV=1 CANONICAL=Q08D99-1" }, "locus": { "chromosome": "1", "start_pos": 81704184, "end_pos": 81696499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104506.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104506.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098603.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098603.1" } ] } }, { "isoform_ac": "A0ABI0NIQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIQ0/entry", "sequence": { "sequence": "MRSGNRRFGFPDRGVGGRDLGFSPGTGDRAASTRSWAGRLNWNRALALAGICMLPAARECCLVPSGFFFFFLVAEGNAAPYFGLILLEHLCSPHWIAIGRCSRRLPRPRPDPYLHPTFAPMWTPQPNVLAGALFGPWLGLLLCCVLTSVGATGCYLLSSVFGKQLVVFYFPDKVALLQKKVEENRNGLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETAFKLLAIALVALVPGTLIKKFSQKDLRLKETSNTHSLNSRKVT", "length": 299, "header": "tr|A0ABI0NIQ0-1|A0ABI0NIQ0_BOVIN Computationally mapped isoform of Transmembrane protein 41A OS=Bos taurus OX=9913 GN=TMEM41A PE=3 SV=1 CANONICAL=Q08D99-1" }, "locus": { "chromosome": "1", "start_pos": 81704399, "end_pos": 81696679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148663.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148663.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104117.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104117.1" } ] } }, { "isoform_ac": "Q08D99-1", "url": "https://www.uniprot.org/uniprotkb/Q08D99/entry#Q08D99-1", "sequence": { "sequence": "MHSLLGLLLVFAGSTFALYLLSTRLPRASTLVSAEESGDRSLWFPSDLAELRELSEVLREYRKEHQVYVFLLFCSAYLYKQSFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLLSSVFGKQLVVFYFPDKVALLQKKVEENRNGLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETAFKLLAIALVALVPGTLIKKFSQKDLRLKETSNTHSLNSRKVT", "length": 264, "header": "sp|Q08D99-1|TM41A_BOVIN Isoform 1 of Transmembrane protein 41A OS=Bos taurus OX=9913 GN=TMEM41A PE=2 SV=1 CANONICAL=Q08D99-1" }, "locus": { "chromosome": "1", "start_pos": 81704399, "end_pos": 81696499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022752.8", "url": "https://www.ensembl.org/id/ENSBTAT00000022752.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022752.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022752.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505368", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505368", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LPS6-1", "protein_name": "Transmembrane protein 41A", "gene_name": "TMEM41A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPLLGLLLVFAGCTFALYLLSTRLPRGETLGSAEGAGDRSLWFPSDVAELRELSEVLREYRKEHQAYVFLLFCSAYLYKQGFAIPGSSFLNVLAGALFGPWLGLLLCCVLASVGATCCYLLSSVFGKQLVVSYFPDKVALLQRKVEENRNSLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDAIFSWETAFKLLAIALVALVPGTLIKKFSQKNLYLNETSNTHHVNSRKHT", "length": 264 }, "evidence": [ { "id": "Q08D99", "url": "https://omabrowser.org/oma/group/Q08D99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q502G2-1", "protein_name": "Transmembrane protein 41A-A", "gene_name": "tmem41aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRSLVGLVAVIVTATFYLYSLSVFLPPGPQLHKQSHEGETTDAKDGDEPSEMETASSRLKFPSDLDELKEMAELLQFYKTEHTGYVLLLFCSAYLYKQAFAIPGSSFLNILAGALFGTWFGLLLTCVLTTVGATLCFLLSQAFGKHHIVKLFPDKVAMLQKKVEENRSSLFFFLLFLRFFPMSPNWFLNMTSPILNIPVTLFFMAVFIGLMPYNFICVQTGSMLSQISSLDDLFSWSVVLKLLLTACVALLPGALIRKYSTRHLHLDGLETNGLSQNKKNR", "length": 281 }, "evidence": [ { "id": "Q08D99", "url": "https://omabrowser.org/oma/group/Q08D99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q08D99", "url": "https://www.uniprot.org/uniprotkb/Q08D99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08D99-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 264, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08D99-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08D99" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DA4-1", "uniprot_ac": "Q08DA4", "uniprot_id": "PHTF1_BOVIN", "mass": { "chemical_mass": 87159.0, "monoisotopic_mass": 87159.0 }, "refseq": { "ac": "NP_001069545", "name": "protein PHTF1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069545" }, "gene_names": [ { "name": "PHTF1", "type": "recommended", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ] }, { "name": "PHTF1", "type": "synonym", "evidence": [ { "id": "NP_001069545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069545" } ] } ], "protein_names": [ { "name": "Protein PHTF1", "type": "recommended", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4/entry#names_and_taxonomy" } ] }, { "name": "protein PHTF1", "type": "synonym", "evidence": [ { "id": "NP_001069545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069545" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PHTF1", "url": "https://www.uniprot.org/uniprotkb/Q08DA4", "locus": { "chromosome": "3", "start_pos": 29696827, "end_pos": 29624990, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019615", "url": "https://www.ensembl.org/id/ENSBTAG00000019615" } ] } } ], "crossref": [ { "id": "Q08DA4", "url": "https://alphafold.ebi.ac.uk/entry/Q08DA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019615", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019615", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536504", "url": "https://www.ncbi.nlm.nih.gov/gene/536504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536504", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536504", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMWQTRE", "url": "https://omabrowser.org/oma/group/KMWQTRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M3T0", "url": "https://www.orthodb.org/?gene=A0A3Q1M3T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MC62", "url": "https://www.orthodb.org/?gene=A0A3Q1MC62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N534", "url": "https://www.orthodb.org/?gene=A0A3Q1N534", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q08DA4", "url": "https://www.orthodb.org/?gene=Q08DA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12680:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12680:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3T0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MC62", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N534", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N534", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N534-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N534-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S701", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S701-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S701-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DA4-1", "url": "https://www.uniprot.org/uniprotkb/Q08DA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 762, "header": "sp|Q08DA4-1|PHTF1_BOVIN Isoform 1 of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M3T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3T0/entry", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 730, "header": "tr|A0A3Q1M3T0-1|PHTF1_BOVIN Computationally mapped isoform of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=2 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29696316, "end_pos": 29625360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087367.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087367.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064837.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064837.2" } ] } }, { "isoform_ac": "A0A3Q1MC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC62/entry", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 717, "header": "tr|A0A3Q1MC62-1|PHTF1_BOVIN Computationally mapped isoform of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29696316, "end_pos": 29625360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084866.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084866.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067902.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067902.1" } ] } }, { "isoform_ac": "A0A3Q1N534-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N534/entry", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 710, "header": "tr|A0A3Q1N534-1|PHTF1_BOVIN Computationally mapped isoform of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29696316, "end_pos": 29625360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079095.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079095.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065114.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065114.1" } ] } }, { "isoform_ac": "A0AAA9RVM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVM1/entry", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 709, "header": "tr|A0AAA9RVM1-1|PHTF1_BOVIN Computationally mapped isoform of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29696316, "end_pos": 29625360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114518.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114518.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076384.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076384.1" } ] } }, { "isoform_ac": "A0AAA9S701-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S701/entry", "sequence": { "sequence": "CTSKWESGIEKKDGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRVSEITTL", "length": 742, "header": "tr|A0AAA9S701-1|PHTF1_BOVIN Computationally mapped isoform of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29695766, "end_pos": 29653250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128829.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128829.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080972.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080972.1" } ] } }, { "isoform_ac": "A0AAA9SR73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR73/entry", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 689, "header": "tr|A0AAA9SR73-1|PHTF1_BOVIN Computationally mapped isoform of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29696316, "end_pos": 29625360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100479.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100479.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085470.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085470.1" } ] } }, { "isoform_ac": "A0AAA9TTQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTQ4/entry", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 718, "header": "tr|A0AAA9TTQ4-1|PHTF1_BOVIN Computationally mapped isoform of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29696316, "end_pos": 29625360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124693.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124693.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101736.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101736.1" } ] } }, { "isoform_ac": "Q08DA4-1", "url": "https://www.uniprot.org/uniprotkb/Q08DA4/entry#Q08DA4-1", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVIALVLYFMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKARGVETLESAPLNGSFWRTLFGNRMKRVKLICNRGTETDYDSGCLHPIIKKRQCRPEIRMWQTREKAKFSDGEKGRRESFRRLGNGISDDLSSDDDGEAQTQMMILRRSVEGASSDNGCEIKSRKSILSRHLNTQVKKTTSKWCSVVRDSDSLAESEFESAAFSQGSRSGMSGGSRSLNMLRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVSSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNIVTIGLAFFPFLHRLFREKNLDQLKSISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDAYNWEFLIWESALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 762, "header": "sp|Q08DA4-1|PHTF1_BOVIN Isoform 1 of Protein PHTF1 OS=Bos taurus OX=9913 GN=PHTF1 PE=2 SV=1 CANONICAL=Q08DA4-1" }, "locus": { "chromosome": "3", "start_pos": 29696316, "end_pos": 29625360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026132.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026132.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026132.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026132.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 179, "start_aa": "Asn", "end_pos": 179, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn179", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 180, "start_aa": "Asn", "end_pos": 180, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn180", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 197, "start_aa": "Asn", "end_pos": 197, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn197", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 431, "start_aa": "Asn", "end_pos": 431, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn431", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 674, "start_aa": "Asn", "end_pos": 674, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn674", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 733, "start_aa": "Asn", "end_pos": 733, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn733", "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [ { "start_pos": 272, "end_pos": 272, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "site_lbl": "Ser272" }, { "start_pos": 276, "end_pos": 276, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "site_lbl": "Ser276" }, { "start_pos": 277, "end_pos": 277, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "site_lbl": "Ser277" }, { "start_pos": 334, "end_pos": 334, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "site_lbl": "Ser334" }, { "start_pos": 336, "end_pos": 336, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "site_lbl": "Ser336" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:536504", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536504", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AUQ6-1", "protein_name": "Putative homeodomain transcription factor 1", "gene_name": "PHTF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKADLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVLFPFFSTWWIQVTSLRIFVWLLLLYLMQVIALVLYFLMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTANGDGSRENGNNSSDKARGIETLESAPFNGGFWGTLFGNRIKRVKLICNKGTETDNDSSCLHPVIKKRQCRPEFRMWQTREKAKFSDGEKGRRESFRHLGNGISDDLSSEEDGEARTQMMILRRSVEGASSDNGCEVKNRKSVLSRHLNTQVKKTTSKWCPIMRDSDSLAESEFESAAFSQGSRSGMSGGSRSLSMSRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGARVNSLHSGTKRDPKEDVFQQNHLFWLQNSSPASDRVSAIIWEGSECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNVVTIGLAFFPFLHRLFREKSLDQLKTISAEEILTLFCGAPPVTPIIILSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSFLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLRGHKTFLNDVYNWEFLIWESALLLFLLRLVSLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 762 }, "evidence": [ { "id": "Q08DA4", "url": "https://omabrowser.org/oma/group/Q08DA4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1M8G0-1", "protein_name": "Protein 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"glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HQI5-1", "protein_name": "Homeodomain transcription factor 1 isoform X1", "gene_name": "Phtf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKSDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVTAIVLYLMMPIVNVSEVLGPLCLMLLMGTVHCQIVSTQITKPSGNNGNRRRRKLRKTVNGDGSRDNGNNSSDKVRAVETLQSAPSVGGFWGTLFGNRIKRVKLVSNKGTETDNDSGCLHPIIKKRQGRPEIRMWQAREKAKVSDGEKCHREAYRHLGNGISDDLSSEEDGDARTQMILLRRSVEGASSDNGCEFKNRKSVFSRHLNSQVKKATTRWCHIVRDSDSLAESEFESTAFSQGSRSGVSAGSRSLNLSRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGTHVNTLHSGTKRDPKEDVFQQNHLFWLQNSSPASERVSAIIWEGNECKKMDMSVLEISGIIMSRVNEYQQGVGYQMLGNAVTIGLAFFPFLYRLFREKSLDQLKSISAEEVLTLFCGAPPVTPVVVLSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDVYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 762 }, "evidence": [ { "id": "Q08DA4", "url": "https://omabrowser.org/oma/group/Q08DA4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9QZ09-1", "protein_name": "Protein PHTF1", "gene_name": "Phtf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGFKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSSWWIQVTSLRIFVWLLLLYLMQVTAVVLYLLMPIVSASEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRDNGNNSPDKVRAVETLESASSVGGFWGTLFGNRIKRVKLVSNKGTETDNDSGCFHPILKKRQGRPEIRMWQAREKAKVSDGEKCRREAYRRLGNGISDDLSSEEDGEARTQMILLRRSVEGASSDNGYEVKNRRSILSRHLNSQVKKTTRWCHIVRDSDSLAESEFESAVFSQGSRSGMSGGSRSLNLSRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVNTIHSGTKRDPKEDVFQQNHLFWLQNSSPASERVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYEQGVGYQMLGNAVTVGLALFPFLYRLFREKSFDQLKSISAEEVLTLFCGAPPVTPVVILSIINFIERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 761 }, "evidence": [ { "id": "Q08DA4", "url": "https://omabrowser.org/oma/group/Q08DA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UMS5-1", "protein_name": "Protein PHTF1", "gene_name": "PHTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGLKNKPKKMGHIKPDLIDVDLIRGSTFAKAKPEIPWTSLTRKGLVRVVFFPLFSNWWIQVTSLRIFVWLLLLYFMQVIAIVLYLMMPIVNISEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNNSSDKVRGIETLESVPIIGGFWETIFGNRIKRVKLISNKGTETDNDPSCVHPIIKRRQCRPEIRMWQTREKAKFSDGEKCRREAFRRLGNGVSDDLSSEEDGEARTQMILLRRSVEGASSDNGCEVKNRKSILSRHLNSQVKKTTTRWCHIVRDSDSLAESEFESAAFSQGSRSGVSGGSRSLNMSRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVNTLHSGTKRDPKEDVFQQNHLFWLQNSSPSSDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNVVTIGLAFFPFLHRLFREKSLDQLKSISAEEILTLFCGAPPVTPIIVLSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS", "length": 762 }, "evidence": [ { "id": "Q08DA4", "url": "https://omabrowser.org/oma/group/Q08DA4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V9A8-1", "protein_name": "Protein phtf", "gene_name": "phtf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLDEIVAWYQKRIGTYDKQEWEKTVEQRILDGFNSVNLKNTKLKTELIDVDLVRGSTFPKAKPKQSLLTVIRLAILRYVLLPLYAQWWVKQTTPNAFGFILVLYLTQLTNWAIYVLHSSRIVPLDYEKPPNGTLLQAEADGDASDKDADKESEEHAALLSALLIPCALSLLISLIHSQIVATNTASGVSGGSSKNKLRRISASYLSDKAATRENRVRRRKKIVRVRQVEADLSQASSNISLPNRRTATSTIEVLPRPVTPLPSPTVTCATVPDPTTPTTPSPSVIRRSTNEETYLTTTAISPLTQPLAAIDACYDLSRKAGGAAPESPKKRNVNWHTPIQIYATYELGEEPCSSRKVAEESAPESVGERLCSVKPDYQTRRNIGEDDGFESLNGKSSSGEDNNHSPLPNAVAVAAPPAPVQTNQLRLRLNTTNGVTASASPTEKKPQSRGNESSTSCAESDECDDADIMSSPASGCNQECTTSATDWLGVTTNSEDCSYTSDLDHSDGGLKHTAFSDEDPGELDITPTTILNPHSSLDRISCTIWDQRDAKKAQLSVLEIASCIIERVDSMGEANDYIYIGVVFSFLLTLIPIFCRLCEVTLGSDAEKASEISYFNMPQLLWEKSSASLFTLLGLAFGDSQWERMVLALGFVQRLCLTLILFIIFAVAERTFKQRFLYAKLFSHLTSSRRARKSNLPHFRLNKVRNIKTWLSVRSYLKKRGPQRSVDIIVSAAFIVTLLLLAFLSVEWLKDSAHLHTHLTLEALIWSITIGIFLLRFMTLGQKIQHKYRSVSVLITEQINLYLQIEQKPKKKDELMVSNSVLKLAADLLKELETPFKLSGLSANPYLFTTIKVVILSALSGVLSEVLGFKLKLHKIKIK", "length": 880 }, "evidence": [ { "id": "Q08DA4", "url": "https://omabrowser.org/oma/group/Q08DA4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q08DA4", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DA4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 762, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DA4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DA4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q08DA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DA4" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHTF", "eco_id": "ECO_0000255", "start_pos": 6, "end_pos": 150, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 179, 180, 197, 431, 674, 733 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 272, 276, 277, 334, 336 ], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 733, "end_pos": 735 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 6 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_n_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ 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"https://www.ncbi.nlm.nih.gov/protein/XP_024848471" } ] } ], "function": [ { "annotation": "Acts as a guanine nucleotide exchange factor (GEF) for ARF1.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M506", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M506#function" }, { "database": "UniProtKB", "id": "ARBA00056967", "url": "https://www.uniprot.org/uniprotkb/ARBA00056967#function" }, { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IQSEC3", "url": "https://www.uniprot.org/uniprotkb/G5E5L9", "locus": { "chromosome": "5", "start_pos": 107137449, "end_pos": 107048490, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019058", "url": "https://www.ensembl.org/id/ENSBTAG00000019058" } ] } } ], "crossref": [ { "id": "G5E5L9", "url": "https://alphafold.ebi.ac.uk/entry/G5E5L9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019058", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019058", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13318", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13318", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "786925", "url": "https://www.ncbi.nlm.nih.gov/gene/786925", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024848471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848471", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M506", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M506", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M506-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M506-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5L9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5L9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESLLENPVRAVLYLKELTAIVQNQQSLIHTQRQRIDELERRLDELSAENRSLWEHQQLLQAQPPPGLVPPSPATAGAQEQLQDHGQLPPAAPQPAPEQPPLQHHGQLLAQPQPGPSGRAHAPQSPHQHPVAPGAVADKEKERPPSCCAAAGTLLQHKSPAALGKGVLSRRPENETVLHQFCCPAADAEQKPACSDLGPHSDGACAQAGGGTEDSVAAAAAGRPSAHARKAQAQQLQEEEERPGAGGASPRAGPHRAASPGRQQPALATALCSRAPAASDYEISLDLKNKQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKARAPTAESLAAERALLEGCSLAGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLQESGAYQIHRALRAGAGPPGLEGEAREPEGASPGAGAEPTEPPSPPQGHGSTLMMAFRDVTVQIASQNISVSSSTALSVANCLGAQTAPVPADSAVVKAEEGQARAQEAPEGPEAPSAGQGIAPAEDRSAEVEAGGALSASSPMAAGPAVEEEEEEETEEAAKETEAELEAGDNSEQLSSSSTSTKSAKSGSEASASASKEALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELRSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLLVILKLCPKKKSSSTYTFCRSVGLLGMQFHLFENEYYSHGITLVTPLLGSEKKQVLHFCALGLDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKAGGSQGDPQSKQGSPTAKREAAAAGEKAAESSVEVSIHNRLQVSPHSSGPGAERGAPLPDLQPSPSREQPPPPPPPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYAPASSDSCGSTPLGGPDSPLKVVHRPPLPPPPPPYNHPHQFCPPGSLLHQRRCSSGSRSLV", "length": 1181, "header": "tr|G5E5L9-1|G5E5L9_BOVIN Isoform 1 of IQ motif and SEC7 domain-containing protein 3 OS=Bos taurus OX=9913 GN=IQSEC3 PE=3 SV=3 CANONICAL=G5E5L9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M506-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M506/entry", "sequence": { "sequence": 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"5", "start_pos": 107133903, "end_pos": 107106145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072203.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072203.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063357.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063357.1" } ] } }, { "isoform_ac": "G5E5L9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5L9/entry", "sequence": { "sequence": "MESLLENPVRAVLYLKELTAIVQNQQSLIHTQRQRIDELERRLDELSAENRSLWEHQQLLQAQPPPGLVPPSPATAGAQEQLQDHGQLPPAAPQPAPEQPPLQHHGQLLAQPQPGPSGRAHAPQSPHQHPVAPGAVADKEKERPPSCCAAAGTLLQHKSPAALGKGVLSRRPENETVLHQFCCPAADAEQKPACSDLGPHSDGACAQAGGGTEDSVAAAAAGRPSAHARKAQAQQLQEEEERPGAGGASPRAGPHRAASPGRQQPALATALCSRAPAASDYEISLDLKNKQIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKARAPTAESLAAERALLEGCSLAGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTWSLKTMCSLQESGAYQIHRALRAGAGPPGLEGEAREPEGASPGAGAEPTEPPSPPQGHGSTLMMAFRDVTVQIASQNISVSSSTALSVANCLGAQTAPVPADSAVVKAEEGQARAQEAPEGPEAPSAGQGIAPAEDRSAEVEAGGALSASSPMAAGPAVEEEEEEETEEAAKETEAELEAGDNSEQLSSSSTSTKSAKSGSEASASASKEALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELRSNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFNDLLVILKLCPKKKSSSTYTFCRSVGLLGMQFHLFENEYYSHGITLVTPLLGSEKKQVLHFCALGLDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKAGGSQGDPQSKQGSPTAKREAAAAGEKAAESSVEVSIHNRLQVSPHSSGPGAERGAPLPDLQPSPSREQPPPPPPPPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYAPASSDSCGSTPLGGPDSPLKVVHRPPLPPPPPPYNHPHQFCPPGSLLHQRRCSSGSRSLV", "length": 1181, "header": "tr|G5E5L9-1|G5E5L9_BOVIN Isoform 1 of IQ motif and SEC7 domain-containing protein 3 OS=Bos taurus OX=9913 GN=IQSEC3 PE=3 SV=3 CANONICAL=G5E5L9-1" }, "locus": { "chromosome": "5", "start_pos": 107137446, "end_pos": 107048490, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025372.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025372.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025372.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025372.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1084, "start_aa": "Thr", "end_pos": 1084, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1084", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 458, "start_aa": "Thr", "end_pos": 458, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr458", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "G5E5L9", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5L9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1181, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5L9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5L9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5L9" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 643, "end_pos": 836, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 458, 1084 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P82924-1", "uniprot_ac": "P82924", "uniprot_id": "RT30_BOVIN", "mass": { "chemical_mass": 49356.0, "monoisotopic_mass": 49356.0 }, "refseq": { "ac": "NP_001073063", "name": "large ribosomal subunit protein mL65", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063" }, "gene_names": [ { "name": "MRPS30", "type": "recommended", "evidence": [ { "id": "P82924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82924" } ] }, { "name": "MRPS30", "type": "synonym", "evidence": [ { "id": "NP_001073063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein mL65", "type": "recommended", "evidence": [ { "id": "P82924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82924/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S30, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001073063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063" }, { "id": "P82924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82924/entry#names_and_taxonomy" } ] }, { "name": "MRP-S30", "type": "synonym", "evidence": [ { "id": "NP_001073063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063" }, { "id": "P82924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82924/entry#names_and_taxonomy" } ] }, { "name": "S30mt", "type": "synonym", "evidence": [ { "id": "NP_001073063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063" }, { "id": "P82924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82924/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein mL65", "type": "synonym", "evidence": [ { "id": "NP_001073063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063" } ] }, { "name": "programmed cell death 9", "type": "synonym", "evidence": [ { "id": "NP_001073063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P82924", "url": "https://www.uniprot.org/uniprotkb/P82924" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MRPS30", "url": "https://www.uniprot.org/uniprotkb/P82924", "locus": { "chromosome": "20", "start_pos": 30060705, "end_pos": 30070007, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000084", "url": "https://www.ensembl.org/id/ENSBTAG00000000084" } ] } } ], "crossref": [ { "id": "P82924", "url": "https://alphafold.ebi.ac.uk/entry/P82924", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000084", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000084", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "516084", "url": "https://www.ncbi.nlm.nih.gov/gene/516084", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "P82924", "url": "https://www.ebi.ac.uk/intact/interactors/id:P82924*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR010793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516084", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516084", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNMPRYY", "url": "https://omabrowser.org/oma/group/VNMPRYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M6Z3", "url": "https://www.orthodb.org/?gene=A0A3Q1M6Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P82924", "url": "https://www.orthodb.org/?gene=P82924", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13014", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13014", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13014:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13014:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001073063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073063", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P82924", "url": "https://www.uniprot.org/uniprotkb/P82924", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P82924-1", "url": "https://www.uniprot.org/uniprotkb/P82924-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATRCWRFVLRSPGLSLHTAAEATVTAPEVTGSDVKAAPVARYPPIVASLTADSKAARQRRVERWQATVHAAKSVDEKLRILTKMQFMKYVVYPQTFALNADRWYQSFTKTVFLSGLPPPQAQPDREPAQVVDLAALRAAVCDCLLQEHFFLRRKKRAPIYQERYAVASPFLDQLVPSLTGLLSAYNPVLAAAALDCNRPVHFYWLRGEEIIPGGHRKGRVDAVRYQINDKPHNQIRISRQLPEFVPLDYSVPVEVPVKNCKPDKLPLFKRQYENAIFIGTKTADPLCYGHTQFHLLPDKLKRERLLKQNCADQIEVIFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQGVITDGKYFSFFCYQLNTLALTAQADQNNPRKNICWGTQSMPLYETIEDNDVKGFNDDVLLQLVHFLLNRPEEDKAQLLVN", "length": 435, "header": "sp|P82924-1|RT30_BOVIN Isoform 1 of Large ribosomal subunit protein mL65 OS=Bos taurus OX=9913 GN=MRPS30 PE=1 SV=4 CANONICAL=P82924-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Z3/entry", "sequence": { "sequence": "MAATRCWRFVLRSPGLSLHTAAEATVTAPEVTGSDVKAAPVARYPPIVASLTADSKAARQRRVERWQATVHAAKSVDEKLRILTKMQFMKYVVYPQTFALNADRWYQSFTKTVFLSGLPPPQAQPDREPAQVVDLAALRAAVCDCLLQEHFFLRRKKRAPIYQERYAVASPFLDQLVPSLTGLLSAYNPVLAAAALGKPRAAFRGGGGGDSRGPWVRGCVPSRFSSVRLSAASWPVFVPLDYSVPVEVPVKNCKPDKLPLFKRQYENAIFIGTKTADPLCYGHTQFHLLPDKLKRERLLKQNCADQIEVIFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQGVITDGKYFSFFCYQLNTLALTAQADQNNPRKNICWGTQSMPLYETIEDNDVKGFNDDVLLQLVHFLLNRPEEDKAQLLVN", "length": 426, "header": "tr|A0A3Q1M6Z3-1|RT30_BOVIN Computationally mapped isoform of Large ribosomal subunit protein mL65 OS=Bos taurus OX=9913 GN=MRPS30 PE=1 SV=1 CANONICAL=P82924-1" }, "locus": { "chromosome": "20", "start_pos": 30070000, "end_pos": 30060775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082379.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082379.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065801.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065801.1" } ] } }, { "isoform_ac": "P82924-1", "url": "https://www.uniprot.org/uniprotkb/P82924/entry#P82924-1", "sequence": { "sequence": "MAATRCWRFVLRSPGLSLHTAAEATVTAPEVTGSDVKAAPVARYPPIVASLTADSKAARQRRVERWQATVHAAKSVDEKLRILTKMQFMKYVVYPQTFALNADRWYQSFTKTVFLSGLPPPQAQPDREPAQVVDLAALRAAVCDCLLQEHFFLRRKKRAPIYQERYAVASPFLDQLVPSLTGLLSAYNPVLAAAALDCNRPVHFYWLRGEEIIPGGHRKGRVDAVRYQINDKPHNQIRISRQLPEFVPLDYSVPVEVPVKNCKPDKLPLFKRQYENAIFIGTKTADPLCYGHTQFHLLPDKLKRERLLKQNCADQIEVIFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQGVITDGKYFSFFCYQLNTLALTAQADQNNPRKNICWGTQSMPLYETIEDNDVKGFNDDVLLQLVHFLLNRPEEDKAQLLVN", "length": 435, "header": "sp|P82924-1|RT30_BOVIN Isoform 1 of Large ribosomal subunit protein mL65 OS=Bos taurus OX=9913 GN=MRPS30 PE=1 SV=4 CANONICAL=P82924-1" }, "locus": { "chromosome": "20", "start_pos": 30070000, "end_pos": 30060775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000091.5", "url": "https://www.ensembl.org/id/ENSBTAT00000000091.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000091.4", "url": "https://www.ensembl.org/id/ENSBTAP00000000091.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Cavdar Koc E, Burkhart W, Blackburn K, Moseley A, Spremulli LL", "evidence": [ { "database": "UniProtKB", "id": "P82924", "url": "https://www.uniprot.org/uniprotkb/P82924" } ], "reference": [ { "type": "PubMed", "id": "11279123", "url": "https://glygen.org/publication/PubMed/11279123" } ] } ], "pathway": [ { "id": "bta:516084", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516084", "resource": "KEGG Pathway" }, { "id": "R-BTA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-BTA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-BTA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A833-1", "protein_name": "Mitochondrial ribosomal protein S30", "gene_name": "Mrps30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARYWKLVPRGRGFSQNAAAKASTSGTEVSDLEVVATPVARYPPIVASMTADSKAARQRRVQRWQATVHAAPSVDEKIRILTKVQFKKYVVHPQIPALNADRWYQGFTKTVFVSGLPPAPALSPPSFDLAGLRAAVCDCILQEHVYVRRRQPQSRFDRRQALASSLLDQVVGTLVNLLAPLNPVLTTAALDYKRPVDFYWLRGEERILAGHRKGHIDALRYQINDKPHNQIRISKQLPEFVPLDHSIPAEIPVMKYKPDKLPLFKRQYENRIFTGSKLADPRCYGHTQFHLLPDILNRERLIKQNQADQVEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQGVITDGKYFSFFCYQLNTLALTVQADQNNPRKNICWGTQSKPLYETVEDNEVKGFDDDVLLQIVHFLLNKPKEDRAQLLTNQEKELDPRP", "length": 440 }, "evidence": [ { "id": "P82924", "url": "https://omabrowser.org/oma/group/P82924/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D0G0-1", "protein_name": "Large ribosomal subunit protein mL65", "gene_name": "Mrps30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAARYWKLVPRGRGLSQNAAAKASATAPEVRDLEVVATPVARYPPIVASMTADSKAARQRRVQRWQATVHAAPSVDEKIRILTKMQFKKYVVHPQISALNADRWYQSFTKTVFVSGLPPAPALSPPPPSLDLAALRAAVCDCILQEQVYVRRRRPRSLFDRRQALASSILDQVVRTLVNLLAPLNPVLSTAALDCKRSVDFYWLRGEERIPAGHRKGHIDALRYQINDKPHNQIRISKQLPEFVPLDYSIPTEIPVMKCKPDKLPLFRRQYENSIFTGSKTADPCCYGHTQFHLIPDRLKRERLIRQNQAEQVEAVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYFSFFCYQLNTLALTVQADQNNPRKNLCWGSQSQPLYETVEDNDVKGFDDGTLLQIVHFLLNKPREDGAQLLASQEKELDLGP", "length": 442 }, "evidence": [ { "id": "P82924", "url": "https://omabrowser.org/oma/group/P82924/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP92-1", "protein_name": "Large ribosomal subunit protein mL65", "gene_name": "MRPS30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAARCWRPLLRGPRLSLHTAANAAATATETTCQDVAATPVARYPPIVASMTADSKAARLRRIERWQATVHAAESVDEKLRILTKMQFMKYMVYPQTFALNADRWYQYFTKTVFLSGLPPPPAEPEPEPEPEPEPALDLAALRAVACDCLLQEHFYLRRRRRVHRYEESEVISLPFLDQLVSTLVGLLSPHNPALAAAALDYRCPVHFYWVRGEEIIPRGHRRGRIDDLRYQIDDKPNNQIRISKQLAEFVPLDYSVPIEIPTIKCKPDKLPLFKRQYENHIFVGSKTADPCCYGHTQFHLLPDKLRRERLLRQNCADQIEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAVITDGKYFSFFCYQLNTLALTTQADQNNPRKNICWGTQSKPLYETIEDNDVKGFNDDVLLQIVHFLLNRPKEEKSQLLEN", "length": 439 }, "evidence": [ { "id": "P82924", "url": "https://omabrowser.org/oma/group/P82924/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXP3-1", "protein_name": "Mitochondrial ribosomal protein S30, isoform A", "gene_name": "mRpS30", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKLNRVRHLRTTYKRCLSGQSQLQLNSTDAEPAYPEIQDLSFKARKQKDAANWHEEIRQVPTVEEKMIKINMPRYYGFKVVDFNDSKIPYNALPLTQHYTRTVLEDLPSETDKKAQAKDSEQEQEQPSVDGLFKAARGDVIDALEFAHDYYKHLEKQHNSAESNPVERERILTQIIVEQLNRALLQSLSEEYKHLDELDVDYNPRHEAFWAVGGVDPPKNVQKSKKGREWQKDMANESVDRMVQYTGAPYLALRHRKQLTPWKTEAESENLELSKQLPRFKHDPRTLGYSTKHQHATNVPGYWPKGNENNFGLLSFQSRAHLQIRPKSFGEQDQLEALHSLAIKSSYAWLLAQANYNGFNTYNELTYPMNTQTVITNGREWSFYEYQLNTLLLHGTNVAENPRVNFCRGTKPLPLYAEISASGKCVDFNDNALRHLLNFYANAPSIQRSIGEQQPYVASDVSAYENAEQRDFINKTFKYLASNRPRHLELPEIYLWEKLYKIDNNNRAMEAKRRFFELDINPWQRTLDTHDKEYVPRAVRPDVPKNKNRFKKTYYP", "length": 557 }, "evidence": [ { "id": "P82924", "url": "https://omabrowser.org/oma/group/P82924/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "P82924", "url": "https://www.uniprot.org/uniprotkb/P82924" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P82924", "url": "https://www.uniprot.org/uniprotkb/P82924" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P82924", "url": "https://www.uniprot.org/uniprotkb/P82924" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "P82924", "url": "https://www.uniprot.org/uniprotkb/P82924" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "P82924", "url": 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"alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P82924-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P82924" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DC7-1", "uniprot_ac": "Q08DC7", "uniprot_id": "RGS19_BOVIN", "mass": { "chemical_mass": 25353.0, "monoisotopic_mass": 25353.0 }, "refseq": { "ac": "NP_001070383", "name": "regulator of G-protein signaling 19", "summary": "", 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], "function": [ { "annotation": "Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 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"https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539036", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EANQHMV", "url": "https://omabrowser.org/oma/group/EANQHMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MIQ4", "url": "https://www.orthodb.org/?gene=A0A3Q1MIQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q08DC7", "url": "https://www.orthodb.org/?gene=Q08DC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845:SF145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845:SF145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001070383", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070383", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTN4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTN4", "database": "UniProtKB", 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Isoform 1 of Regulator of G protein signaling 19 OS=Bos taurus OX=9913 GN=RGS19 PE=2 SV=1 CANONICAL=Q08DC7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MIQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIQ4/entry", "sequence": { "sequence": "MPLRAEGTPRLLPAREQDAPPPACGKAWGRSGFRSLGVGRGREAGRPGGASRRLGAERRLGAEPASGLKRRWCLAALSPLQPCLLHCPHLQDVLLQPQVLLPCSVPQAWSAPSAESLGADPQAVVTETGVLEQAPRSPGNLLHPSMPTPPEAEKQQTGPEEADQPPSMSSHDAAPPAPPRRNPCCLCWCCCCSCSWNEERRRAWRASRESRLQPLPSCEVCATPTPTPTPTPEEVRSWAQSFDKLMHSPAGRSVFREFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPAYRALLLQGASQSSSEA", "length": 368, "header": "tr|A0A3Q1MIQ4-1|RGS19_BOVIN Computationally mapped isoform of Regulator of G protein signaling 19 OS=Bos taurus OX=9913 GN=RGS19 PE=2 SV=1 CANONICAL=Q08DC7-1" }, "locus": { "chromosome": "13", "start_pos": 53803653, "end_pos": 53800571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073856.2", "url": 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"ENSBTAP00000076383.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076383.1" } ] } }, { "isoform_ac": "A0AAA9SWF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWF2/entry", "sequence": { "sequence": "MGTQAPRRSARSGGEGAGGARSRQSSGRGGPGRAPPRARKSRPRALGKCGRGACALKPAPSPRRSGRTSERAGRRLRRERLGSAADPQAVVTETGVLEQAPRSPGNLLHPSMPTPPEAEKQQTGPEEADQPPSMSSHDAAPPAPPRRNPCCLCWCCCCSCSWNEERRRAWRASRESRLQPLPSCEVCATPTPTPTPTPEEVRSWAQSFDKLMHSPAGRSVFREFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPAYRALLLQGASQSSSEA", "length": 334, "header": "tr|A0AAA9SWF2-1|RGS19_BOVIN Computationally mapped isoform of Regulator of G protein signaling 19 OS=Bos taurus OX=9913 GN=RGS19 PE=2 SV=1 CANONICAL=Q08DC7-1" }, "locus": { "chromosome": "13", "start_pos": 53803653, "end_pos": 53798036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110632.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110632.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087560.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087560.1" } ] } }, { "isoform_ac": "Q08DC7-1", "url": "https://www.uniprot.org/uniprotkb/Q08DC7/entry#Q08DC7-1", "sequence": { "sequence": "MPTPPEAEKQQTGPEEADQPPSMSSHDAAPPAPPRRNPCCLCWCCCCSCSWNEERRRAWRASRESRLQPLPSCEVCATPTPTPTPTPEEVRSWAQSFDKLMHSPAGRSVFREFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPAYRALLLQGASQSSSEA", "length": 223, "header": "sp|Q08DC7-1|RGS19_BOVIN Isoform 1 of Regulator of G protein signaling 19 OS=Bos taurus OX=9913 GN=RGS19 PE=2 SV=1 CANONICAL=Q08DC7-1" }, "locus": { "chromosome": "13", "start_pos": 53803653, "end_pos": 53801473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054910.4", "url": "https://www.ensembl.org/id/ENSBTAT00000054910.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050801.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050801.2" } ] } } ], "glycosylation": [ { 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"database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 82, "start_aa": "Thr", "end_pos": 82, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr82", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, 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[ { "database": "UniProtKB", "id": "Q08DC7", "url": "https://www.uniprot.org/uniprotkb/Q08DC7" } ], "site_lbl": "Ser103" }, { "start_pos": 157, "end_pos": 157, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by MAPK1 and MAPK3", "evidence": [ { "database": "UniProtKB", "id": "Q08DC7", "url": "https://www.uniprot.org/uniprotkb/Q08DC7" } ], "site_lbl": "Ser157" }, { "start_pos": 24, "end_pos": 24, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DC7", "url": "https://www.uniprot.org/uniprotkb/Q08DC7" } ], "site_lbl": "Ser24" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539036", "resource": "KEGG Pathway" }, { "id": "R-BTA-416476", "name": "", "url": 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}, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q08DC7", "url": "https://www.uniprot.org/uniprotkb/Q08DC7" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "Q08DC7", "url": "https://www.uniprot.org/uniprotkb/Q08DC7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "Q08DC7", "url": "https://www.uniprot.org/uniprotkb/Q08DC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { 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"length": 1598, "header": "tr|G5E699-1|G5E699_BOVIN Isoform 1 of Transmembrane protein 131-like OS=Bos taurus OX=9913 GN=TMEM131L PE=3 SV=2 CANONICAL=G5E699-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MMR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMR6/entry", "sequence": { "sequence": "MAGPRRPQPGCYRRTAAAVNLLLGVFHVLLPCGRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEDDTEEQSQEQSFSDKLFSGKGLHFQPSVLDFGVQFLGQPAAKILYAYNPSRESEVVVNSVFTAARHFHVPPVHCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSHGVLSYHVSGFGTRVMSAKGSAEQLPNAYFLLPQVQTVQLSQTQAETTNSSLLQVQLECSLHNKVCQRLKSCYVESDDVLRLQMSIIVTMENTSKEFEENTQDLLDHLSIIYVATDKSESSDDSAVNMYILHSGNSLIWIQDVRHFSQRDVLSLQFEPVLLPTSTTNFTKIASFTCKAPSCESGAREDGKKKDTPTLKACLSSPVVQGYFRMDPSATQFHIENHENTSGLWSLWYLNHFDHGVVLNDVFVSKETKHVLKILNFTGPLFLPPGCWKIFSLKLAVKDIAINVFTHVFLTTNIGAVFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAENPDWEGSLSLDPSTWDVDSELANTLYERWKKLKHGDVCKRTVLGVTRFAHSKKSKESEPFAVFLPRLVPEPGLVLNFSATALRNSMVKYFVVKNPSSWPVSLQLLPVSLYPKPEAAARLLHKWFGTDMQMINLTTSEFQLTKACPYLGVRSEGSRFGILHLHLQPLERKRVGVVFTPADYGKVSSLILIRNNLTVIDMIGVEGFGARELLKVGGRLPGTGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVTSLKINGYNCQGYGFEVLDCHQFSLGPNTSRDISIVFTPDFTSSWVIRELTLVTAADLEFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNASSSSQQSTAPVDVISAHSHKSNCKNFLDAYAPSDKGRGKSCLPVSSPQSRTQNATKRSPATCGHSQKKHKCSVYYGRHRGAAVASSAGAPSEDRPAPAKAGGCPAGAGEAWVGLRCAGGLSANLQKSLALPRSFLGKDENTLKSAVAASSPSSECHVKEGAQTCVFPKETDFQVSESVAELKEREVCPMKTPKKLPENHLPRSSPQCQSDLPDISRKNNGNNQQVPVKNEVDNCESLKKVDTKSSSEKKIHKAAKEDGCSEKQDIPSIEQEDPYRKKALQEKKEGNVQNLNWNKNRMCRKNKKRGAAQVLRPSDQSELKLVCSEFERSELSSDINVRNWRIQENPGEACKAGASSGSSLPATQGEAEGYFQKPGKKGAEKSCSDSGSDCGSSSGSVRASRGSWGSWSSASSSDGDRKPAVGPLRCLLPGDSVSQNDFSSEAPISLNLSRNISFINIGLPAPADAPCPSLPAGPAAAEEQGLCAPGDLWPAQPVCVTGGFGCALESGGPAALPPPAAVPSSSFIDWNATCEGQFPSVYCPLELNDYNAFPEEGMNYPSGFPCPAEVQTDFIDHSSPSAWGSPPSVPTAWGHASLISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCAINPTTEHSAHMENQAVMCKEYYPGFNPFRAYMDLDIWTSTANRNANFPLSRDSSYCGNV", "length": 1596, "header": "tr|A0A3Q1MMR6-1|G5E699_BOVIN Computationally mapped isoform of Transmembrane protein 131-like OS=Bos taurus OX=9913 GN=TMEM131L PE=3 SV=1 CANONICAL=G5E699-1" }, "locus": { "chromosome": "17", "start_pos": 4171058, "end_pos": 3995947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071745.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071745.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070747.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070747.1" } ] } }, { "isoform_ac": "A0ABI0NSV5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV5/entry", "sequence": { "sequence": "MGFSDKLFSGKGLHFQPSVLDFGVQFLGQPAAKILYAYNPSRESEVVVNSVFTAARHFHVPPVHCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSHGVLSYHVSGFGTRVMSAKGSAEQLPNAYFLLPQVQTVQLSQTQAETTNSSLLQVQLECSLHNKVCQRLKSCYVESDDVLRLQMSIIVTMENTSKEFEENTQDLLDHLSIIYVATDKSESSDDSAVNMYILHSGNSLIWIQDVRHFSQRDVLSLQFEPVLLPTSTTNFTKIASFTCKAPSCESGAREDGKKKDTPTLKACLSSPVVQGYFRMDPSATQFHIENHENTSGLWSLWYLNHFDHGVVLNDVFVSKETKHVLKILNFTGPLFLPPGCWKIFSLKLAVKDIAINVFTHVFLTTNIGAVFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAENPDWEGSLSLDPSTWDVDSELANTLYERWKKLKHGDVCKRTVLGVTRFAHSKKSKESEPFAVFLPRLVPEPGLVLNFSATALRNSMVKYFVVKNPSSWPVSLQLLPVSLYPKPEAAARLLHKWFGTDMQMINLTTSEFQLTKACPYLGVRSEGSRFGILHLHLQPLERKRVGVVFTPADYGKVSSLILIRNNLTVIDMIGVEGFGARELLKVGGRLPGTGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVTSLKINGYNCQGYGFEVLDCHQFSLGPNTSRDISIVFTPDFTSSWVIRELTLVTAADLEFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNASSSSQQSTAPVDVISAHSHKSNCKNFLDAYAPSDKGRGKSCLPVSSPQSRTQNATKRSPATCGHSQKKHKCSVYYGRHRGAAVASSAGAPSEDRPAPAKAGGCPAGAGEAWVGLRCAGGLSANLQKSLALPRSFLGKDENTLKSAVAASSPSSECHVKEGAQTCVFPKETDFQVSESVAELKEREVCPMKTPKKLPENHLPRSSPQCQSDLPDISRKNNGNNQQVPVKNEVDNCESLKKVDTKSSSEKKIHKAAKEDGCSEKQDIPSIEQEDPYRKKALQEKKEGNVQNLNWNKNRMCRKNKKRGAAQVLRPSDQSELKLVCSEFERSELSSDINVRNWRIQENPGEACKAGASSGSSLPATQGEAEGYFQKPGKKGAEKSCSDSGSDCGSSSGSVRASRGSWGSWSSASSSDGDRKPAVGPLRCLLPGDSVSQNDFSSEAPISLNLSRNICNPTDVSGLPAPADAPCPSLPAGPAAAEEQGLCAPGDLWPAQPVCVTGGFGCALESGGPAALPPPAAVPSSSFIDWNATCEGQFPSVYCPLELNDYNAFPEEGMNYPSGFPCPAEVQTDFIDHSSPSAWGSPPSVPTAWGHASLISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCAINPTTEHSAHMENQAVMCKEYYPGFNPFRAYMDLDIWTSTANRNANFPLSRDSSYCGNV", "length": 1520, "header": "tr|A0ABI0NSV5-1|A0ABI0NSV5_BOVIN Computationally mapped isoform of Transmembrane protein 131-like OS=Bos taurus OX=9913 GN=TMEM131L PE=3 SV=1 CANONICAL=G5E699-1" }, "locus": { "chromosome": "17", "start_pos": 4087231, "end_pos": 3995947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139893.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139893.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106144.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106144.1" } ] } }, { "isoform_ac": "G5E699-1", "url": "https://www.uniprot.org/uniprotkb/G5E699/entry", "sequence": { "sequence": "MAGPRRPQPGCYRRTAAAVNLLLGVFHVLLPCGRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEDDTEEQSQEQSFSDKLFSGKGLHFQPSVLDFGVQFLGQPAAKILYAYNPSRESEVVVNSVFTAARHFHVPPVHCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSHGVLSYHVSGFGTRVMSAKGSAEQLPNAYFLLPQVQTVQLSQTQAETTNSSLLQVQLECSLHNKVCQRLKSCYVESDDVLRLQMSIIVTMENTSKEFEENTQDLLDHLSIIYVATDKSESSDDSAVNMYILHSGNSLIWIQDVRHFSQRDVLSLQFEPVLLPTSTTNFTKIASFTCKAPSCESGAREDGKKKDTPTLKACLSSPVVQGYFRMDPSATQFHIENHENTSGLWSLWYLNHFDHGVVLNDVFVSKETKHVLKILNFTGPLFLPPGCWKIFSLKLAVKDIAINVFTHVFLTTNIGAVFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAENPDWEGSLSLDPSTWDVDSELANTLYERWKKLKHGDVCKRTVLGVTRFAHSKKSKESEPFAVFLPRLVPEPGLVLNFSATALRNSMVKYFVVKNPSSWPVSLQLLPVSLYPKPEAAARLLHKWFGTDMQMINLTTSEFQLTKACPYLGVRSEGSRFGILHLHLQPLERKRVGVVFTPADYGKVSSLILIRNNLTVIDMIGVEGFGARELLKVGGRLPGTGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVTSLKINGYNCQGYGFEVLDCHQFSLGPNTSRDISIVFTPDFTSSWVIRELTLVTAADLEFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNASSSSQQSTAPVDVISAHSHKSNCKNFLDAYAPSDKGRGKSCLPVSSPQSRTQNATKRSPATCGHSQKKHKCSVYYGRHRGAAVASSAGAPSEDRPAPAKAGGCPAGAGEAWVGLRCAGGLSANLQKSLALPRSFLGKDENTLKSAVAASSPSSECHVKEGAQTCVFPKETDFQVSESVAELKEREVCPMKTPKKLPENHLPRSSPQCQSDLPDISRKNNGNNQQVPVKNEVDNCESLKKVDTKSSSEKKIHKAAKEDGCSEKQDIPSIEQEDPYRKKALQEKKEGNVQNLNWNKNRMCRKNKKRGAAQVLRPSDQSELKLVCSEFERSELSSDINVRNWRIQENPGEACKAGASSGSSLPATQGEAEGYFQKPGKKGAEKSCSDSGSDCGSSSGSVRASRGSWGSWSSASSSDGDRKPAVGPLRCLLPGDSVSQNDFSSEAPISLNLSRNICNPTDVSGLPAPADAPCPSLPAGPAAAEEQGLCAPGDLWPAQPVCVTGGFGCALESGGPAALPPPAAVPSSSFIDWNATCEGQFPSVYCPLELNDYNAFPEEGMNYPSGFPCPAEVQTDFIDHSSPSAWGSPPSVPTAWGHASLISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCAINPTTEHSAHMENQAVMCKEYYPGFNPFRAYMDLDIWTSTANRNANFPLSRDSSYCGNV", "length": 1598, "header": "tr|G5E699-1|G5E699_BOVIN Isoform 1 of Transmembrane protein 131-like OS=Bos taurus OX=9913 GN=TMEM131L PE=3 SV=2 CANONICAL=G5E699-1" }, "locus": { "chromosome": "17", "start_pos": 4171058, "end_pos": 3995947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052841.3", "url": "https://www.ensembl.org/id/ENSBTAT00000052841.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049631.3", "url": "https://www.ensembl.org/id/ENSBTAP00000049631.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2VDJ0-1", "protein_name": "Transmembrane protein 131-like", "gene_name": "TMEM131L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGELLLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSRDSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVLSYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNKVCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDSAVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKATSCDSGIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRSVVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGAIFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELANKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATALRSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTEACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVEGFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADLEFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSRIQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKEDICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNGNNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWCIQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSLPQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPVHNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTWNTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHSTHMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV", "length": 1609 }, "evidence": [ { "id": "G5E699", "url": "https://omabrowser.org/oma/group/G5E699/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZRG1-1", "protein_name": "Transmembrane protein 131-like", "gene_name": "Tmem131l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAFEPLPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSDKLFIGKGLHFQPSVLDFGIQFLGYPAAKLLYAYNPSRDSEVVVNSVFTAARHFHVPPVHCRVIPAMGKTSFRIIFLPTEEGSFESSLFINTSSHGVFSYHVSGVGTRRASTEGSAEQLPNAHLLLPQVQSIQLSQTQAETTNTSLLRVQLECSLHNKVCQQLKSCYLGSDDTLHLEMNIIVAVENSSKQPEENTQALLDHLTIVYVATDESETSDESAVNMYVLHSGSSLIWIQDIHHFSQKNLLSLQFEPVLLSTSTTNFTKVASFTCRAGTSCDSGIVGIRRRKDTPTMKACLSSPVVQGYFRVDASTAQFHIESHKTATGVWSIWYQGHFDHSIVLKDVFVSKETKHILKVLSFRGPLFLPPGCWNIFSLKLAVKGVVLNLFTNVFLTTNTGAVFAIPLQIFSAPAKEGSLGFEVLAHCGMHYFMGKSKPETPDWERSLSLDRSTWDVDSELANKLYERWKKYKNGDVCRRNVLGMSQFAFAKKSKETEPFVSFLPRVVLEPGLVLNFSATALRNSVVKYFVVRNPSPWPVSLQLLPLSLYPRPEAAVRLLYKWFGTDMQMVNLSTGEFQLTKACPYQGEPSEESSLGALHVHLQPFDMRKVGVVFTPADYGKVTSLILIRNNLTVVDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCHRQLKDSKQILSITKNFKVENVGPLPITVTSLKINGYNCQGYGFEVLDCHPFSLSPNTSRDISIVFTPDFTSSWVIRELTLVTAAELEFHFTLNVTLPHHMLPLCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNGSSSPQQNGDPVDMISSHSHKSTCKNFLDTYSPSDKGRGKSCLPVGPPLSRLQNAAKRSPATYSHSQKKHKCSFYYSKQKPSASTASSANITTEEKQTVTLASSLSAAKEDLCTNILNENWASLRYASGVNGSLQRNLTLPKNVLNKEESSLKNTVVSNTSSECSMKEGIQTCMFPKETDSKISEHVAELKEQEPCPQKTSKKPPESTLPKTPPQYPQSDLPEVSRKHGNNQQVPVKNEVDSFETVKAVDTKLSSVKKTQRESPEDTCSEKQDSPSAEQDDPYRKRKLQEKREGNTQTLNWNKTRTCRKHKKRASVQAPSSPRPSEQSEQRLVCSDVRSWCAQDSTGETCKAGIEIVGDSPVRREEDSSYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSRDSWSSSSSDCDRKPVVDIQQFLPPGDGVSPRDSPSEASMPLSLPQHVCSSTDVNGLSGFTESCPGLPAAPADAGEEKGLYPPGGLWPSQPVCLTSSFNCPVENGAPGVSEEPTSIPDSSFIDWSTSCEGQFSSVYCPLELNGYNAFPEENMNYTNGFPCSSKVQTDFIGHGTSSTWNTPASMPAAWGHASLVNSPSYLTSTRSLSPMSGLFGSIWAPQSDAYENCCPVSPATEHSTHMENQVMCKEYYLGFNPFRAYMNLDIWTSTANRSANFPLSRDSGYCGNV", "length": 1596 }, "evidence": [ { "id": "G5E699", "url": "https://omabrowser.org/oma/group/G5E699/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U3D7-1", "protein_name": "Transmembrane protein 131-like", "gene_name": "Tmem131l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAFEPLPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSDKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYAYNPSRESEVVVNSVFTAARHFHVPPVHCRVIPAMGKASFRVIFLPTEEGSIESSLFINTSSHGVFSYHVSGVGTRRVSTEGSAEQLPNAYFLLPQVQSIQLSQTQAETTNTSLLRVQLECSLHNKVCQQLKSCSLGSDDALHLEMNIIVAVENSSKQPEENTQALLDHLSIVYVATDESDTSDESAVNMYVLHSGNSLIWIQDIHHFSQKNVLSLQFEPVLLSTSTTNFTKIASFTCKAGTSCDSGIMGLRKKKASPAMQACLSSPVVQGYFRTDASTAQFHIESHETATGVWSIWYRSHFDQSIVLKDVFVSKETKHILKVLSFRGPLFLPPGCWNIFSLKLAVKGIVLNLFTNVFLTTNTGAIFAIPLQIFSAPTKEGSLGFEVLAHCGMHYFMGKSKTENPNWERSLSLDRSTWDMDSELANKLYERWKKYKSGDACRRNVLGMSQFAFTKKSKETEPFVSFLPRVVPEPNLVLNFSATALRNSAVKYFVVRNPTPQPVSLQLLPLSLYPRPEAAVRLLHKWFGTDMQMVNLSTGEFQLTQACPYQGEPSEESSLGALHVHLQALETRRVGVVFTPADYGKVTSLILIRNNLTVVDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCHRQLKDSKQILSITKNFKVENIGPLPITVTSLKINGYNCQGYGFEVLDCHPFSLSPNTSRDISIVFTPDFTSSWVIRELTLVTAADLEFHFTLNVTLPHHMLPLCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNGSSSSQQNGDPVAMISSHPHKSTCKNFLDTYSPSDKGRGKSCLPVGPSLSRLQNAAKRSPATYGHSQKKHKCSFYYSKQKPSASAASSANVTTEEKQTVTLASSLSVAKEDICTNVLSENWVSLRYASGINGSLQKNLTLPKNVLHKEESSLKNTVVTNTPSECSMKEGVHTYMFPKETDSKISENVAELKEQEPCPQKTSKKPPESTLPKTPPQYLQSDLPEVSRKHGNKQQAPVRSEVDSFEPVRAADAEPSSVRKTQGASPEDTCSEKQDTPSAEQEDPSRKRKLQERREGSTQALNWNKTRPCRRNKKRASAQASSSPRPSEQSEQRLVCSDVRSWCAQDGAGEKCKAGTEVSGSSPERREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRRPVVDIQHFLPPGDGVSPQNFPSEASVPLSLPQHVCSSTDVSVLPEFTESPCPGLPATPAGAGEEKGLYPPGGLWPSQPVCLTSSFNCPVENGAPGVSQEPTSIPDSSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYTNGFPCSSKVQTDFIGHSTPSTWNTPASMPAAWGHASLVNSPSYLTSTRSLSPMSGLFGSIWAPQSEVYETCCPISPATEHATHMENQVMCKEYYLGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNM", "length": 1597 }, "evidence": [ { "id": "G5E699", "url": "https://omabrowser.org/oma/group/G5E699/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E699", "url": "https://www.uniprot.org/uniprotkb/G5E699" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E699", "url": "https://www.uniprot.org/uniprotkb/G5E699" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E699", "url": "https://www.uniprot.org/uniprotkb/G5E699" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "G5E699", "url": "https://www.uniprot.org/uniprotkb/G5E699" } ], "pmid": "" }, { "name": "negative regulation of immature T cell proliferation in thymus", "id": "GO:0033088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033088", "evidence": [ { "database": "UniProtKB", "id": "G5E699", "url": "https://www.uniprot.org/uniprotkb/G5E699" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1354, "end_pos": 1356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1436, "end_pos": 1438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 808, "end_pos": 810, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" }, { "start_pos": 907, "end_pos": 909, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E699" }, { "id": "PF24501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMEM131L fifth Ig-like", "eco_id": "ECO_0000259", "start_pos": 772, "end_pos": 836, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E699" }, { "id": "PF24499", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24499" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMEM131L fourth Ig-like", "eco_id": "ECO_0000259", "start_pos": 591, "end_pos": 722, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E699", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E699" }, { "id": "PF24498", "database": 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZFTRAF1", "url": "https://www.uniprot.org/uniprotkb/P0DW91", "locus": {} } ], "crossref": [ { "id": "P0DW91", "url": "https://alphafold.ebi.ac.uk/entry/P0DW91", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035254", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16505", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16505", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22861", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22861", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "125505915", "url": "https://www.ncbi.nlm.nih.gov/gene/125505915", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "282612", "url": "https://www.ncbi.nlm.nih.gov/gene/282612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:125505915", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:125505915", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HERPEHE", "url": "https://omabrowser.org/oma/group/HERPEHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DI73", "url": "https://www.orthodb.org/?gene=A0A452DI73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P0DW91", "url": "https://www.orthodb.org/?gene=P0DW91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23059", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23059", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23059:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23059:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23059:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23059:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23059:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23059:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21362", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21362", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28124", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28124", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A452DI73", "url": "https://www.uniprot.org/uniprotkb/A0A452DI73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DI73-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLI9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLI9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY39", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY39-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0DW91", "url": "https://www.uniprot.org/uniprotkb/P0DW91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0DW91-1", "url": "https://www.uniprot.org/uniprotkb/P0DW91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAEEAGGGGPAAGPAGSVPAGVGVGAGAGAGVGVGAGPGAAAGPAAAAALGEAAGPGLPDEAGLAGARQLQEAAGDPDAPPKKRLRAAEAAEAAAAAAAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLCQFPRSILERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVKISPVIYHFVFTNESNETDYVPLPIVDSVECNKLLAAKNINLRLFLFQIQK", "length": 410, "header": "sp|P0DW91-1|ZTRF1_BOVIN Isoform 1 of Zinc finger TRAF-type-containing protein 1 OS=Bos taurus OX=9913 GN=ZFTRAF1 PE=3 SV=1 CANONICAL=P0DW91-1" }, "isoforms": [ { "isoform_ac": "A0A452DI73-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI73/entry", "sequence": { "sequence": "MTPRPGGEWSSALSHLALGAVSLHAALSTAQANRGAAAGFLLQALATATMLASGLGTDEDCLAGAWVATVIGLPLLAFDFHWCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLCQFPRSILERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVKISPVIYHFVFTNESNETDYVPLPIVDSVECNKLLAAKNINLRLFLFQIQK", "length": 362, "header": "tr|A0A452DI73-1|ZTRF1_BOVIN Computationally mapped isoform of Zinc finger TRAF-type-containing protein 1 OS=Bos taurus OX=9913 GN=ZFTRAF1 PE=3 SV=1 CANONICAL=P0DW91-1" }, "locus": { "chromosome": "14", "start_pos": 492293, "end_pos": 479318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010192.5", "url": "https://www.ensembl.org/id/ENSBTAT00000010192.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010192.4", "url": "https://www.ensembl.org/id/ENSBTAP00000010192.4" } ] } }, { "isoform_ac": "A0AAA9SLI9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLI9/entry", "sequence": { "sequence": "MSGAEEAGGGGPAAGPAGSVPAGVGVGAGAGAGVGVGAGPGAAAGPAAAAALGEAAGPGLPDEAGLAGARQLQEAAGDPDAPPKKRLRAAEAAEAAAAAAAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLCQFPRSILERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTVVPPKLACAFVCPNGFDLPCDK", "length": 302, "header": "tr|A0AAA9SLI9-1|ZTRF1_BOVIN Computationally mapped isoform of Zinc finger TRAF-type-containing protein 1 OS=Bos taurus OX=9913 GN=ZFTRAF1 PE=3 SV=1 CANONICAL=P0DW91-1" }, "locus": { "chromosome": "14", "start_pos": 491778, "end_pos": 481386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134137.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134137.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086111.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086111.1" } ] } }, { "isoform_ac": "A0AAA9SY39-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY39/entry", "sequence": { "sequence": "MVVDPERGLVSNKPEGFSRNMDSASSLARLRSPAVNFLRLPGQQLVFLSKKGNVQDQLWGSLSTWPDGPVVRRAPGLRRYRSPCSPGTRWSYEYLCKCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLCQFPRSILERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVKISPVIYHFVFTNESNETDYVPLPIVDSVECNKLLAAKNINLRLFLFQIQK", "length": 377, "header": "tr|A0AAA9SY39-1|ZTRF1_BOVIN Computationally mapped isoform of Zinc finger TRAF-type-containing protein 1 OS=Bos taurus OX=9913 GN=ZFTRAF1 PE=3 SV=1 CANONICAL=P0DW91-1" }, "locus": { "chromosome": "14", "start_pos": 492293, "end_pos": 480254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101177.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101177.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090278.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090278.1" } ] } }, { "isoform_ac": "P0DW91-1", "url": "https://www.uniprot.org/uniprotkb/P0DW91/entry#P0DW91-1", "sequence": { "sequence": "MSGAEEAGGGGPAAGPAGSVPAGVGVGAGAGAGVGVGAGPGAAAGPAAAAALGEAAGPGLPDEAGLAGARQLQEAAGDPDAPPKKRLRAAEAAEAAAAAAAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLCQFPRSILERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVKISPVIYHFVFTNESNETDYVPLPIVDSVECNKLLAAKNINLRLFLFQIQK", "length": 410, "header": "sp|P0DW91-1|ZTRF1_BOVIN Isoform 1 of Zinc finger TRAF-type-containing protein 1 OS=Bos taurus OX=9913 GN=ZFTRAF1 PE=3 SV=1 CANONICAL=P0DW91-1" }, "locus": { "chromosome": "14", "start_pos": 492293, "end_pos": 481386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133298.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133298.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095950.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095950.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Assessment of the gene content of the chromosomal regions flanking bovine DGAT1.", "journal": "Genomics", "date": "2004", "authors": "Winter Andreas, Alzinger Ariane, Fries Ruedi", "evidence": [ { "database": "UniProtKB", "id": "P0DW91", "url": "https://www.uniprot.org/uniprotkb/P0DW91" } ], "reference": [ { "type": "PubMed", "id": "14667821", "url": "https://glygen.org/publication/PubMed/14667821" } ] } ], "pathway": [ { "id": "bta:125505915", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:125505915", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P0DTL6-5", "protein_name": "Zinc finger TRAF-type-containing protein 1", "gene_name": "ZFTRAF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGAEEAGGGGPAAGPAGSVPAGVGVGVGAGPGAAAGQAAAAALGEAAGPGLPDEAGLAGARQLQLQEAAGDPDAPPKKRLRAAEAAEAAAAAAAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVRISPVIYHFVFTNESNETDYVPLPIIDSVECNKLLAAKNINLRLFLFQIQK", "length": 404 }, "evidence": [ { "id": "P0DW91", "url": "https://omabrowser.org/oma/group/P0DW91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW87-1", "protein_name": "Zinc finger TRAF-type-containing protein 1", "gene_name": "Zftraf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGAEEAGGGGPAAGPAGAVPAGVGVGAGPGAAAGPAAAALGEAAGPGIPDEAALAGARQLQEAAGDPDAPPKKRLRAAEAAEAAAAAVAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVRISPVIYHFVFTNESNETDYVPLPIIDSVECNKLLAAKNINLRLFLFQIQK", "length": 399 }, "evidence": [ { "id": "P0DW91", "url": "https://omabrowser.org/oma/group/P0DW91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DW89-1", "protein_name": "Zinc finger TRAF-type-containing protein 1", "gene_name": "Zftraf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGAEEAGGGGPAAGPAGAVPAGVGVGVGPGAAAGPAAAALGEAAGPGIPDEAGLAGARQLQEAAGDPDAPPKKRLRAAEAAEAAAAAVAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVRISPVIYHFVFTNESNETDYVPLPIIDSVECNKLLAAKNINLRLFLFQIQK", "length": 399 }, "evidence": [ { "id": "P0DW91", "url": "https://omabrowser.org/oma/group/P0DW91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08CH8-1", "protein_name": "Zinc finger TRAF-type-containing protein 1", "gene_name": "zftraf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSMEERMELGVAAAPGSSSSGLGVGPVGGALDAGPGSAGLAGIQEESGVRRDGSVGEADPDAPPKKRVRLQEGEAGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADSRLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECSYCLKQFPRSGLDRHQTEECQDRVTQCKYKRIGCPWQGPFHELSAHEAECCHPSKTGMELMGILDEMDQSHRRELQLYNSIFSLLCFEKIGFTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLAFQLILKSKVNSALECSFLLLKGPYEDIKIKPVIQHHVFSNDANETEYAPLPICDSVECNKLLAAKNINLRLFIFQIQK", "length": 382 }, "evidence": [ { "id": "P0DW91", "url": "https://omabrowser.org/oma/group/P0DW91/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9VZV5-1", "protein_name": "Zinc finger TRAF-type-containing protein 1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVESSSSAVQQPPSSSNLPLLGDNQAVATTSSASSASSSSTSSSSSSVGGGNVVGVPLDTQGSGEPPAKKQLLDGGGGGATSSSGSSLLSSAAAASGMHEKLAHRISNALCCAVCLDLPKTAMYQCQMGHLMCAACFTHLLADGRLRDQIATCPNCRVEISKSTASRNLAVEKAASELPSECQFCNKEFPYKSLERHEQHECQERPTKCKYHRIGCQWRGPYHETNEHERNCLHPQKSGYEVMAALEAHDDRIKEEKKMFNTLIDLLSYEKIIFNDLQMKPYRTDEYVHKLFYETARFSAFNQQWVVKARINNSQRDPHQSNERTITYQLILKTKTSTPMSIHFFALKGPFSDMKVSTQIYKHEFTETSTESEYYVLPLPDGVGGSGSSECNRMLANKGINFRLLMFLLNK", "length": 412 }, "evidence": [ { "id": "P0DW91", "url": "https://omabrowser.org/oma/group/P0DW91/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P0DW91", "url": "https://www.uniprot.org/uniprotkb/P0DW91" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P0DW91", "url": "https://www.uniprot.org/uniprotkb/P0DW91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "P0DW91", "url": "https://www.uniprot.org/uniprotkb/P0DW91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 307, "end_pos": 309 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 375, "end_pos": 377 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5P9-1", "uniprot_ac": "G5E5P9", "uniprot_id": "G5E5P9_BOVIN", "mass": { "chemical_mass": 176313.0, "monoisotopic_mass": 176313.0 }, "refseq": {}, "gene_names": [ { "name": "ERCC6L2", "type": "recommended", "evidence": [ { "id": "G5E5P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ] } ], "protein_names": [ { "name": "DNA excision repair protein ERCC-6-like 2", "type": "recommended", "evidence": [ { "id": "G5E5P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5P9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Promotes double-strand break (DSB) end-joining and facilitates programmed recombination by controlling how DNA ends are joined in a spatially oriented manner during repair. Also plays a role in DNA repair by restricting DNA end resection in double strand break (DSB) repair. Facilitates replication of complex DNA regions and regulates the maintenance of chromatin structure.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RTD8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTD8#function" }, { "database": "UniProtKB", "id": "ARBA00093342", "url": "https://www.uniprot.org/uniprotkb/ARBA00093342#function" }, { "database": "UniProtKB", "id": "A0AAA9SQI4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQI4#function" }, { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ERCC6L2", "url": "https://www.uniprot.org/uniprotkb/G5E5P9", "locus": { "chromosome": "8", "start_pos": 82712671, "end_pos": 82558294, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020626", "url": "https://www.ensembl.org/id/ENSBTAG00000020626" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020626", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020626", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18005", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18005", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PDSEPCH", "url": "https://omabrowser.org/oma/group/PDSEPCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5P9", "url": "https://www.orthodb.org/?gene=G5E5P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RTD8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTD8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIU6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQI4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5P9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPGCQALPPGQMDQSTPKPHAETNSKDIWHPGERCLAPSPDNEKLCEASIKSITVDENGKSFAVILYSNFQERRVPLKRLQEVKSVKDCSRNFIFDDEDLEKPYFPDRKFPSSAVPFQLSENGDSIPYTINRYLRDYQREGAQFLYGHFIQGRGCILGDDMGLGKTVQVISFLAAVLGKKGTREDIENNMPEFLLRNMKKDPPSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTILHGNKKDSELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEIMKALRCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSRIHFKKQFSDPVEHGQRHTATKRELATGRKAMQRLARKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVSLILQSSEPCTCNSGQKRRNCCYKTNSQGETVKTLYFSYLAVLQKVANHVALLQTASTSRQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNKDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERIKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQVYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGVYNLFKLRSQGSCLTRDILEREGKVEAGIMTATTWLKEEPPVHKLETAREPDCREHRGPEQLAEAACDLCSDFSEDETASNSVTKTVKNKASDSSRASVSPGQFSLLQCGFSKLFETKCETVEDGDENIASDNESSDEQPTCFSTEAKNAGCQKSQDSLGTLKHQKLANVLNPNGKCVFEKSEKILKENIPSESDDEKNFKNTVDHHHILQNVTESEDSDIIFPTQYTTQRFLKKNIRFKPPVDGSEDSESENPVNIKNNGDDTKTNVRGNGLISKQLNLEIETLKSNTKRKGGSDISDESDDIEVFCKSRVRKQRATSSLRFKRKKENKRELYTFPKTMKKANQQCATDEDCNSQTIDDFSSSDDNLSVGHISFSKQNHRPKTIKDKISVSSKLTNHKRNSTFIPRKPMKFSNESIVNQNRICESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAARDVFELKQFSQLPANIAVCTSKTHKEKMKGDISTRTKECQPLSEGSISFPLYISHPVSQKKKKVCRIDQTTFIIGETPKGIRRKQFEEMASYFKLSSVKEFAKRVTNATSEERQKMLRDFYTSQYPEVREFFVDSPSECTKSASEKGERVENKSEKRQSLMKEQPSDSETLSFKNSTKKISPIFSPSICKKKSIKFQNHSSCKKKVLSNDVETKKLPISCTQETDGGERSQASEGTAASCSLNSKSGADELGKLENAGKGQQDLTSLGISRNGPIFQVENKTIENPVLEDTSVVGLLGDTSILDDLFKSHENSPTQLPKKVLSGSIEKAKQRPKDFWDILNDQNDDSLSKLTDLAVIETLCEKVPFAASSKRKEDLEASLWKSNEKFLWKKFNSSDTDESTANTQE", "length": 1558, "header": "tr|G5E5P9-1|G5E5P9_BOVIN Isoform 1 of DNA excision repair protein ERCC-6-like 2 OS=Bos taurus OX=9913 GN=ERCC6L2 PE=3 SV=2 CANONICAL=G5E5P9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RTD8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTD8/entry", "sequence": { "sequence": "MQPGCQALPPGQMDQSTPKPHAETNSKDIWHPGERCLAPSPDNEKLCEASIKSITVDENGKSFAVILYSNFQERRVPLKRLQEVKSVKDCSRNFIFDDEDLEKPYFPDRKFPSSAVPFQLSENGDSIPYTINRYLRDYQREGAQFLYGHFIQGRGCILGDDMGLGKTVQVISFLAAVLGKKGTREDIENNMPEFLLRNMKKDPPSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTILHGNKKDSELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEIMKALRCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSRIHFKKQFSDPVEHGQRHTATKRELATGRKAMQRLARKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVSLILQSSEPCTCNSGQKRRNCCYKTNSQGETVKTLYFSYLAVLQKVANHVALLQTASTSRQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNKDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERIKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQVYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGVYNLFKLRSQGSCLTRDILEREGKVEAGIMTATTWLKEEPPVHKLETAREPDCREHRGPEQLAEAACDLCSDFSEDETASNSVTKTVKNKASDSSRASVSPGQFSLLQCGFSKLFETKCETVEDGDENIASDNESSDEQPTCFSTEAKNAGCQKSQDSLGTLKHQKLANVLNPNGKCVFEKSEKILKENIPSESDDEKNFKNTVDHHHILQNVTESEDSDIIFPTQYTTQRFLKKNIRFKPPVDGSEDSESENPVNIKNNGDDTKTNVRGNGLISKQLNLEIETLKSNTKRKGGSDISDESDDIEVFCKSRVRKQRATSSLRFKRKKENKRELYTFPKTMKKANQQCATDEDCNSQTIDDFSSSDDNLSVGHISFSKQNHRPKTIKDKISVSSKLTNHKRNSTFIPRKPMKFSNESIVNQNRICESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAARDVFELKQFSQLPANIAVCTSKEYTISQAVL", "length": 1183, "header": "tr|A0AAA9RTD8-1|G5E5P9_BOVIN Computationally mapped isoform of DNA excision repair protein ERCC-6-like 2 OS=Bos taurus OX=9913 GN=ERCC6L2 PE=3 SV=2 CANONICAL=G5E5P9-1" }, "locus": { "chromosome": "8", "start_pos": 82681131, "end_pos": 82558299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116550.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116550.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076199.2", "url": "https://www.ensembl.org/id/ENSBTAP00000076199.2" } ] } }, { "isoform_ac": "A0AAA9SIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIU6/entry", "sequence": { "sequence": "MQPGCQALPPGQMDQSTPKPHAETNSKDIWHPGERCLAPSPDNEKLCEASIKSITVDENGKSFAVILYSNFQERRVPLKRLQEVKSVKDCSRNFIFDDEDLEKPYFPDRKFPSSAVPFQLSENGDSIPYTINRYLRDYQREGAQFLYGHFIQGRGCILGDDMGLGKTVQVFTYFIIIKSYILCHMYYIHEWIPSANFCLYPRTYYNYFVCLSHK", "length": 214, "header": "tr|A0AAA9SIU6-1|G5E5P9_BOVIN Computationally mapped isoform of DNA excision repair protein ERCC-6-like 2 OS=Bos taurus OX=9913 GN=ERCC6L2 PE=3 SV=2 CANONICAL=G5E5P9-1" }, "locus": { "chromosome": "8", "start_pos": 82563883, "end_pos": 82558299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092479.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092479.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085259.2", "url": "https://www.ensembl.org/id/ENSBTAP00000085259.2" } ] } }, { "isoform_ac": "A0AAA9SQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQI4/entry", "sequence": { "sequence": "MQPGCQALPPGQMDQSTPKPHAETNSKDIWHPGERCLAPSPDNEKLCEASIKSITVDENGKSFAVILYSNFQERRVPLKRLQEVKSVKDCSRNFIFDDEDLEKPYFPDRKFPSSAVPFQLSENGDSIPYTINRYLRDYQREGAQFLYGHFIQGRGCILGDDMGLGKTVQVISFLAAVLGKKGTREDIENNMPEFLLRNMKKDPPSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTILHGNKKDSELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEIMKALRCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSRIHFKKQFSDPVEHGQRHTATKRELATGRKAMQRLARKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVSLILQSSEPCTCNSGQKRRNCCYKTNSQGETVKTLYFSYLAVLQKVANHVALLQTASTSRQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNKDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERIKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQVYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGVYNLFKLRSQGSCLTRDILEREGKVEAGIMTATTWLKEEPPVHKLETAREPDCREHRGPEQLAEAACDLCSDFSEDETASNSVTKTVKNKASDSSRASVSPGQFSLLQCGFSKLFETKCETVEDGDENIASDNESSDEQPTCFSTEAKNAGCQKSQDSLGTLKHQKLANVLNPNGKCVFEKSEKILKENIPSESDDEKNFKNTVDHHHILQNVTESEDSDIIFPTQYTTQRFLKKNIRFKPPVDGSEDSESENPVNIKNNGDDTKTNVRGNGLISKQLNLEIETLKSNTKRKGGSDISDESDDIEVFCKSRVRKQRATSSLRFKRKKENKRELYTFPKTMKKANQQCATDEDCNSQTIDDFSSSDDNLSVGHISFSKQNHRPKTIKDKISVSSKLTNHKRNSTFIPRKPMKFSNESIVNQNRICESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAARDVFELKQFSQLPANIAVCTSKLLAMRSWGILPHSEVTRTAGVMS", "length": 1197, "header": "tr|A0AAA9SQI4-1|G5E5P9_BOVIN Computationally mapped isoform of DNA excision repair protein ERCC-6-like 2 OS=Bos taurus OX=9913 GN=ERCC6L2 PE=3 SV=2 CANONICAL=G5E5P9-1" }, "locus": { "chromosome": "8", "start_pos": 82686708, "end_pos": 82558299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113797.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113797.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088599.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088599.2" } ] } }, { "isoform_ac": "G5E5P9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P9/entry", "sequence": { "sequence": "MQPGCQALPPGQMDQSTPKPHAETNSKDIWHPGERCLAPSPDNEKLCEASIKSITVDENGKSFAVILYSNFQERRVPLKRLQEVKSVKDCSRNFIFDDEDLEKPYFPDRKFPSSAVPFQLSENGDSIPYTINRYLRDYQREGAQFLYGHFIQGRGCILGDDMGLGKTVQVISFLAAVLGKKGTREDIENNMPEFLLRNMKKDPPSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTILHGNKKDSELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEIMKALRCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSRIHFKKQFSDPVEHGQRHTATKRELATGRKAMQRLARKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVSLILQSSEPCTCNSGQKRRNCCYKTNSQGETVKTLYFSYLAVLQKVANHVALLQTASTSRQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNKDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERIKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQVYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGVYNLFKLRSQGSCLTRDILEREGKVEAGIMTATTWLKEEPPVHKLETAREPDCREHRGPEQLAEAACDLCSDFSEDETASNSVTKTVKNKASDSSRASVSPGQFSLLQCGFSKLFETKCETVEDGDENIASDNESSDEQPTCFSTEAKNAGCQKSQDSLGTLKHQKLANVLNPNGKCVFEKSEKILKENIPSESDDEKNFKNTVDHHHILQNVTESEDSDIIFPTQYTTQRFLKKNIRFKPPVDGSEDSESENPVNIKNNGDDTKTNVRGNGLISKQLNLEIETLKSNTKRKGGSDISDESDDIEVFCKSRVRKQRATSSLRFKRKKENKRELYTFPKTMKKANQQCATDEDCNSQTIDDFSSSDDNLSVGHISFSKQNHRPKTIKDKISVSSKLTNHKRNSTFIPRKPMKFSNESIVNQNRICESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAARDVFELKQFSQLPANIAVCTSKTHKEKMKGDISTRTKECQPLSEGSISFPLYISHPVSQKKKKVCRIDQTTFIIGETPKGIRRKQFEEMASYFKLSSVKEFAKRVTNATSEERQKMLRDFYTSQYPEVREFFVDSPSECTKSASEKGERVENKSEKRQSLMKEQPSDSETLSFKNSTKKISPIFSPSICKKKSIKFQNHSSCKKKVLSNDVETKKLPISCTQETDGGERSQASEGTAASCSLNSKSGADELGKLENAGKGQQDLTSLGISRNGPIFQVENKTIENPVLEDTSVVGLLGDTSILDDLFKSHENSPTQLPKKVLSGSIEKAKQRPKDFWDILNDQNDDSLSKLTDLAVIETLCEKVPFAASSKRKEDLEASLWKSNEKFLWKKFNSSDTDESTANTQE", "length": 1558, "header": "tr|G5E5P9-1|G5E5P9_BOVIN Isoform 1 of DNA excision repair protein ERCC-6-like 2 OS=Bos taurus OX=9913 GN=ERCC6L2 PE=3 SV=2 CANONICAL=G5E5P9-1" }, "locus": { "chromosome": "8", "start_pos": 82711563, "end_pos": 82558299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027486.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027486.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027486.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027486.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M9B1-1", "protein_name": "DNA excision repair protein ERCC-6-like 2", "gene_name": "Ercc6l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASAPHPRADSHKDRWCPGERCLAPSLDNKKLCEASIKSITVDENGEPFAVVLYPDFQEKKIPLQRLQEVKSTKDHSRSLIFDDEDLEKPYFPDQKIPSLVSAFQLSEDGDSIPYTINRYLRDYQREGAQFLYRHYIKGRGCILGDDMGLGKTIQVISFLAAVLHKKGTREDIENNMPEFLLKSMKKESSSTARKMFLIVAPLSVLYNWKDELDTWGYFRVTVLHGSKKDNELTRLKQRKCEIALTTYETLRLCLEELNSLEWSAIIVDEAHRIRNPNARVTEVMKAVKCKVRIGLTGTILQNNMKELWCVMDWAVPGLLGSRIHFKKQFSDPVEHGQRHTATKRELATGRKAMHRLAKKMSGYFLRRTKTLIKGQLPKKEDRMVYSSLTDFQKAVYQTVLETEDVALILTSSQPCTCGSGQKRRKCCYKTNSQGDTVRTLCLSYLTVLQKVANHVALLQAASTSKHQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLDQLLNHFRKHRDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERLKIVKEFNSSQDVNICLVSTMAGGLGLNFIGANVVILFDPTWNPANDLQAIDRAYRIGQCRDVKVFRLISLGTVEEIMYLRQVYKQQLHCVVVGSENAKRYFEAVQGSKEHRGELFGVHNLFKLRSQGSCLTRDILETRSQPGELQIISLGFWDFVVKCFIVLHLREGQVEAGIMTATTWLKGEASAQKLETPRDPDCQEPTNVCELYSDMSDEESVGKAVKHKVSGPSRTPGSSAQLTLLQCGFSKLFEAKCESVQDGDGNPVSSDGSSDEQPMCLSAKARQAACQKTWDSVCTSEHQKSDNIQTPDEKCVSDKSEKTLEQNVSSESDDETKCHSTAGHHCMGQGDTESEDSDVIFPTQDPTQRVPKNPICCKLLLGESEDSETEDPVKVNHDDGRQNSGRGNGPVSNFLYLENMTLKSVRKRKGTDDISDESDDIDMFPKSRIRKQRATASLKLKSKKENKRKHYNSPITAKDTNQVCEADGDCSSQVIEDFSSSDDSSSVSHVSFTKLNHRAETVKGKSNLRNKLPGPDKKNNSFIPRKPASFLNERVVSQEQICNSMDKILDGVQEVAYIHSNQNVIGSSRAENHMSRWATRDVFELKQFSQLPANVAVCSSETYKSKVNANAVIPTKKDQPPSDGHISSPLYISHPVSQKKKDVYRTNHTTFIIGETPRGIRRKQFEEMASFYKLSVKEFAEQVTSATSEEQQRMLRDFYSLQHPEVKEFFMDSASELMKSVHEKEERVRNKSKGKESLLKERPSNDSTLSCNDSTNKMSQVYNQKICEGKSVRFQNHGSHKEDTFSSGAEIKKSPVNFTQEIYSERNNHTPKDSMTLFCPDSKSEALETELEGSSGHQWDLTGAGSSRNRPCFKLRNKRVENPVSESTPTEGLLGDTSILNDLFKSHGEGPTQLPKNGPSGPVAKAKQRPKDFWDILNEQNDDSLSKLTDLAVIETLCTKAPRTTASKRKEELEASLWKANEKFLWKTFSSDVDDESISSRERE", "length": 1561 }, "evidence": [ { "id": "G5E5P9", "url": "https://omabrowser.org/oma/group/G5E5P9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T890-4", "protein_name": "DNA excision repair protein ERCC-6-like 2", "gene_name": "ERCC6L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPGSAPPPGRMDPSAPQPRAETSGKDIWHPGERCLAPSPDNGKLCEASIKSITVDENGKSFAVVLYADFQERKIPLKQLQEVKFVKDCPRNLIFDDEDLEKPYFPNRKFPSSSVAFKLSDNGDSIPYTINRYLRDYQREGTRFLYGHYIHGGGCILGDDMGLGKTVQVISFLAAVLHKKGTREDIENNMPEFLLRSMKKEPLSSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTVLHGNRKDNELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEVMKALKCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSGTYFKKQFSDPVEHGQRHTATKRELATGRKAMQRLAKKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVTLILQSSEPCTCRSGQKRRNCCYKTNSHGETVKTLYLSYLTVLQKVANHVALLQAASTSKQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNRDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERLKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQIYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGIHNLFKFRSQGSCLTKDILEREGQVEAGIMTATTWLKEGPPAHKLEMPRQPDCQECRGTEQAAEPLAKEACDLCSDFSDEEPVGATGIKTAKNKAPDSSKASSSPGQLTLLQCGFSKLLETKCKAVEDSDGNTASDDESSDEQPTCLSTEAKDAGCEKNQDSLGTSKHQKLDNILNPKEKHIFYKSEKILEQNISSKSDEKKIKNTDKHCILQNVTESEDSDVICPTQYTTERFPDNSIRFKPPLEGSEDSETEHTVKTRNNDNSRNTDDKRNGIISKKLSPENTTLKSILKRKGTSDISDESDDIEISSKSRVRKRASSLRFKRIKETKKELHNSPKTMNKTNQVYAANEDHNSQFIDDYSSSDESLSVSHFSFSKQSHRPRTIRDRTSFSSKLPSHNKKNSTFIPRKPMKCSNEKVVNQEQSYESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAAHDVFELKQFSQLPANIAVCSSKTYKEKVDADTLPHTKKGQQPSEGSISLPLYISNPVNQKKKKVYHTNQTTFIIGETPKGIRRKQFEEMASYFNSSSVNEFAKHITNATSEERQKMLRDFYASQYPEVKEFFVDSVSQFNNSSFEKGEQRTRKKSDKRESLIKPRLSDSETLSFKDSTNKISQVCSLKTYKRKSVKFQNHISYREEVFFNDAETKKSPVSSTQEIDSGKNSQASEDTVTSRSLNSESETRERRLENTMKDQQDLTRTGISRKEPLLKLENKKIENPVLENTSVISLLGDTSILDDLFKSHGNSPTQLPKKVLSGPMEKAKQRPKDFWDILNEQNDESLSKLTDLAVIETLCEKAPLAAPFKRREEPATSLWKSNEKFLWKKFSPSDTDENATNTQSTT", "length": 1561 }, "evidence": [ { "id": "G5E5P9", "url": "https://omabrowser.org/oma/group/G5E5P9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "double-strand break repair via classical nonhomologous end joining", "id": "GO:0097680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097680", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "cellular response to reactive oxygen species", "id": "GO:0034614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034614", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "G5E5P9", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1058, "end_pos": 1060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1092, "end_pos": 1094, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1105, "end_pos": 1107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1259, "end_pos": 1261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1304, "end_pos": 1306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1327, "end_pos": 1329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1350, "end_pos": 1352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1432, "end_pos": 1434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1545, "end_pos": 1547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 332, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5P9" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 523, "end_pos": 673, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1058, "end_pos": 1060 }, { "start_pos": 1092, "end_pos": 1094 }, { "start_pos": 1105, "end_pos": 1107 }, { "start_pos": 1259, "end_pos": 1261 }, { "start_pos": 1304, "end_pos": 1306 }, { "start_pos": 1327, "end_pos": 1329 }, { "start_pos": 1350, "end_pos": 1352 }, { "start_pos": 1432, "end_pos": 1434 }, { "start_pos": 1545, "end_pos": 1547 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 824, "end_pos": 826 }, { "start_pos": 903, "end_pos": 905 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P0C6R2-1", "uniprot_ac": "P0C6R2", "uniprot_id": "ARMC2_BOVIN", "mass": { "chemical_mass": 96936.0, "monoisotopic_mass": 96936.0 }, "refseq": { "ac": "NP_001069269", "name": "armadillo repeat-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069269" }, "gene_names": [ { "name": "ARMC2", "type": "recommended", "evidence": [ { "id": "P0C6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C6R2" } ] }, { "name": "ARMC2", "type": "synonym", "evidence": [ { "id": "NP_001069269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069269" } ] } ], "protein_names": [ { "name": "Armadillo repeat-containing protein 2", "type": "recommended", "evidence": [ { "id": "P0C6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C6R2/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001069269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069269" } ] } ], "function": [ { "annotation": "Required for sperm flagellum axoneme organization and function. Involved in axonemal central pair complex assembly and/or stability.", "evidence": [ { "database": "UniProtKB", "id": "P0C6R2", "url": "https://www.uniprot.org/uniprotkb/P0C6R2#function" }, { "database": "UniProtKB", "id": "Q3URY6", "url": "https://www.uniprot.org/uniprotkb/Q3URY6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P0C6R2", "url": "https://www.uniprot.org/uniprotkb/P0C6R2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARMC2", "url": "https://www.uniprot.org/uniprotkb/P0C6R2", "locus": { "chromosome": "9", "start_pos": 41119714, "end_pos": 41316372, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000036087", "url": "https://www.ensembl.org/id/ENSBTAG00000036087" } ] } } ], "crossref": [ { "id": "P0C6R2", "url": "https://alphafold.ebi.ac.uk/entry/P0C6R2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000036087", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000036087", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "520151", "url": "https://www.ncbi.nlm.nih.gov/gene/520151", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520151", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520151", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EACIYAY", "url": "https://omabrowser.org/oma/group/EACIYAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P0C6R2", "url": "https://www.orthodb.org/?gene=P0C6R2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21356:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21356:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001069269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069269", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S467", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S467", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S467-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S467-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8E5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8E5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFV2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0C6R2", "url": "https://www.uniprot.org/uniprotkb/P0C6R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0C6R2-1", "url": "https://www.uniprot.org/uniprotkb/P0C6R2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSPNDKKLEKLDPFYLPSLSKQKTSAEIVSEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSVHASSFEFSDSRPISGTRLSPLEFKPKAPASPDTVEDFCLSFPKPPVDPAKIRRISSARARLFRVASQGALLPARTLLPTQPTRVESEETVTTRDSVVKINGIYLTESKAIGHLKRHPLQLTYDGDFSKITEQEMFKGATSVPFHLRSGGDQGKRRPRASSSSRSPDQSRLDIRAGSKADLQEKNTEIEVDEVFWNTRIVPILHDLEKEENIEMVCATCTQLHHALEEGNMLGNKFKRRSVLLKTLYKLVDVGSDLLSLKLAKIILALKVSGKNLLNVCKLIFKISRSEKNDSLIRNDSILESLLEVLRSEDLQANTEAFLYCMGTIKFISGNPEFLHEMMGKGAVEILMSLIKQVNENTKKSGTCLPNSGHLLVQMTATLRNLVDSPLARSKLLSINALPQLCTVMEQHIGDKDVCTNIARIFSKLTSYHDCCVALASYSRCYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIPTLLSLFHTFYKLDLHSGKRWGEGDERPEARRPAQAEDVLIKLTRVLANLAIHPGVGPAIAAHSHIVGLLLATLESKSIDDCEELVINTTATINNLSYYKVKNSIIQDRKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDICDFIVQKNVHKFMIALLDAKHQDICFSACGVLLNLTVDRDKRLILKEGGGIKKLVDCLRDFGPTDWQLASLVCKTLWNFSENITNAASCFGDEAANTLLALLSSFLDEELALNGSFDQDLKNYHKLHWETEFRPVAQQLLNRIKNHHTFLEPLPIPSF", "length": 865, "header": "sp|P0C6R2-1|ARMC2_BOVIN Isoform 1 of Armadillo repeat-containing protein 2 OS=Bos taurus OX=9913 GN=ARMC2 PE=3 SV=1 CANONICAL=P0C6R2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S467-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S467/entry", "sequence": { "sequence": "MLSGLTIDQLPGAERKKKPKAPASPDTVEDFCLSFPKPPVDPAKIRRISSARARLFRVASQGALLPARTLLPTQPTRVESEETVTTRDSVVKINGIYLTESKAIGHLKRHPLQLTYDGDFSKITEQEMFKGATSVPFHLRSGGDQGKRRPRASSSSRSPDQSRLDIRAGSKADLQEKNTEIEVDEVFWNTRIVPILHDLEKEENIEMVCATCTQLHHALEEGNMLGNKFKRRSVLLKTLYKLVDVGSDLLSLKLAKIILALKVSGKNLLNVCKLIFKISRSEKNDSLIRNDSILESLLEVLRSEDLQANTEAFLYCMGTIKFISGNPEFLHEMMGKGAVEILMSLIKQVNENTKKSGTCLPNSGHLLVQMTATLRNLVDSPLARSKLLSINALPQLCTVMEQHIGDKDVCTNIARIFSKLTSYHDCCVALASYSRCYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIPTLLSLFHTFYKLDLHSGKRWGEGDERPEARRPAQAEDVLIKLTRVLANLAIHPGVGPAIAAHSHIVGLLLATLESKSIDDCEELVINTTATINNLSYYKVKNSIIQDRKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDICDFIVQKNVHKFMIALLDAKHQDICFSACGVLLNLTVDRDKRLILKEGGGIKKLVDCLRDFGPTDWQLASLVCKTLWNFSENITNAASCFGDEAANTLLALLSSFLDEELALNGSFDQDLKNYHKLHWETEFRPVAQQLLNRIKNHHTFLEPLPIPSF", "length": 785, "header": "tr|A0AAA9S467-1|ARMC2_BOVIN Computationally mapped isoform of Armadillo repeat-containing protein 2 OS=Bos taurus OX=9913 GN=ARMC2 PE=3 SV=1 CANONICAL=P0C6R2-1" }, "locus": { "chromosome": "9", "start_pos": 41307300, "end_pos": 41196821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088211.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088211.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079917.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079917.1" } ] } }, { "isoform_ac": "A0AAA9S8E5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8E5/entry", "sequence": { "sequence": "MLSPNDKKLEKLDPFYLPSLSKQKTSAEIVSEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSVHASSFEFSDSRPISGTRLSPLEFKPKAPASPDTVEDFCLSFPKPPVDPAKIRRISSARARLFRVASQGALLPARTLLPTQPTRVESEETVTTRDSVVKINGIYLTESKAIGHLKRHPLQLTYDGDFSKITEQEMFKGATSVPFHLRSGGDQGKRRPRASSSSRSPDQSRLDIRAGSKADLQEKNTEIEVDEVFWNTRIVPILHDLEKEENIEMVCATCTQLHHALEEGNMLGNKFKRRSVLLKTLYKLVDVGSDLLSLKLAKIILALKVSGKNLLNVCKLIFKISRSEKNDSLIRNDSILESLLEVLRSEDLQANTEAFLYCMGTIKFISGNPEFLHEMMGKGAVEILMSLIKQVNENTKKSGTCLPNSGHLLVQMTATLRNLVDSPLARSKLLSINALPQLCTVMEQHIGDKDVCTNIARIFSKLTSYHDCCVALASYSRCYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIPTLLSLFHTFYKLDLHSGKRWGEGDERPEARRPAQAEDVLIKLTRVLANLAIHPGVGPAIAAHSHIVGLLLATLESKSIDDCEELVINTTATINNLSYYKVKNSIIQDRKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDICDFIVQKNVHKFMIALLDAKHQDICFSACGVLLNLTVDRDKRLILKEGGGIKKLVDCLRDFGPTDWQLASLVCKTLWNFSENITNAASCFGDEAANTLLALLSSFLDIQPHILGCNNIPICEAENYKK", "length": 835, "header": "tr|A0AAA9S8E5-1|ARMC2_BOVIN Computationally mapped isoform of Armadillo repeat-containing protein 2 OS=Bos taurus OX=9913 GN=ARMC2 PE=3 SV=1 CANONICAL=P0C6R2-1" }, "locus": { "chromosome": "9", "start_pos": 41311116, "end_pos": 41126264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105079.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105079.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078425.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078425.1" } ] } }, { "isoform_ac": "A0AAA9TFV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV2/entry", "sequence": { "sequence": "MLSPNDKKLEKLDPFYLPSLSKQKTSAEIVSEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSVHASSFEFSDSRPISGTRLSPLEFKPKAPASPDTVEDFCLSFPKPPVDPAKIRRISSARARLFRVASQGALLPARTLLPTQPTRVESEETVTTRDSVVKINGIYLTESKAIGHLKRHPLQLTYDGDFSKITEQEMFKGATSVPFHLRSGGDQGKRRPRASSSSRSPDQSRLDIRAGSKADLQEKNTEIEVDEVFWNTRIVPILHDLEKEENIEMVCATCTQLHHALEEGNMLGNKFKRRSVLLKTLYKLVDVGSDLLSLKLAKIILALKVSGKNLLNVCKLIFKISRSEKNDSLIRNDSILESLLEVLRSEDLQANTEAFLYCMGTIKFISGNPEFLHEMMGKGAVEILMSLIKQVNENTKKSGTCLPNSGHLLVQMTATLRNLVDSPLARSKLLSINALPQLCTVMEQHIGDKDVCTNIARIFSKLTSYHDCCVALASYSRCYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIPTLLSLFHTFYKLDLHSGKRWGEGDERPEARRPAQAEDVLIKLTRVLANLAIHPGVGPAIAAHSHIVGLLLATLESKSIDDCEELVINTTATINNLSYYKVKNSIIQDRKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDICDFIVQKNVHKFMIALLDAKHQDICFSACGVLLNLTVDRDKRLILKEGGGIKKLVDCLRDFGPTDWQLASLVCKTLWNFSENITNAASCFGDEAANTLLALLSSFLGCHRTLG", "length": 820, "header": "tr|A0AAA9TFV2-1|ARMC2_BOVIN Computationally mapped isoform of Armadillo repeat-containing protein 2 OS=Bos taurus OX=9913 GN=ARMC2 PE=3 SV=1 CANONICAL=P0C6R2-1" }, "locus": { "chromosome": "9", "start_pos": 41311116, "end_pos": 41119778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096745.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096745.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095730.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095730.1" } ] } }, { "isoform_ac": "P0C6R2-1", "url": "https://www.uniprot.org/uniprotkb/P0C6R2/entry#P0C6R2-1", "sequence": { "sequence": "MLSPNDKKLEKLDPFYLPSLSKQKTSAEIVSEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSVHASSFEFSDSRPISGTRLSPLEFKPKAPASPDTVEDFCLSFPKPPVDPAKIRRISSARARLFRVASQGALLPARTLLPTQPTRVESEETVTTRDSVVKINGIYLTESKAIGHLKRHPLQLTYDGDFSKITEQEMFKGATSVPFHLRSGGDQGKRRPRASSSSRSPDQSRLDIRAGSKADLQEKNTEIEVDEVFWNTRIVPILHDLEKEENIEMVCATCTQLHHALEEGNMLGNKFKRRSVLLKTLYKLVDVGSDLLSLKLAKIILALKVSGKNLLNVCKLIFKISRSEKNDSLIRNDSILESLLEVLRSEDLQANTEAFLYCMGTIKFISGNPEFLHEMMGKGAVEILMSLIKQVNENTKKSGTCLPNSGHLLVQMTATLRNLVDSPLARSKLLSINALPQLCTVMEQHIGDKDVCTNIARIFSKLTSYHDCCVALASYSRCYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIPTLLSLFHTFYKLDLHSGKRWGEGDERPEARRPAQAEDVLIKLTRVLANLAIHPGVGPAIAAHSHIVGLLLATLESKSIDDCEELVINTTATINNLSYYKVKNSIIQDRKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDICDFIVQKNVHKFMIALLDAKHQDICFSACGVLLNLTVDRDKRLILKEGGGIKKLVDCLRDFGPTDWQLASLVCKTLWNFSENITNAASCFGDEAANTLLALLSSFLDEELALNGSFDQDLKNYHKLHWETEFRPVAQQLLNRIKNHHTFLEPLPIPSF", "length": 865, "header": "sp|P0C6R2-1|ARMC2_BOVIN Isoform 1 of Armadillo repeat-containing protein 2 OS=Bos taurus OX=9913 GN=ARMC2 PE=3 SV=1 CANONICAL=P0C6R2-1" }, "locus": { "chromosome": "9", "start_pos": 41311116, "end_pos": 41196821, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006360.6", "url": "https://www.ensembl.org/id/ENSBTAT00000006360.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006360.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006360.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520151", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520151", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YNF8-1", "protein_name": "Armadillo repeat containing 2", "gene_name": "ARMC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKPEPFYRLSVSKQKTSSEIINEARSVLRTLRTQRPFTPAEDQRKLFGSGSSRAPQNRPPSVFSLHASSFDLAESRPASGVRLSPLDYKPILVISSKDEDSSVSLPKPAVDAAEVRKVSDARAQLFRRTSQGDAFPAKMAPLDHHEEKLDCEEPAMMSSLHGTNDNCLAEQRAYTPFNDKSEQLICNEHSGKPEREDVLKGTAGKHLFQLKGESNQMKKHGIVASQPSSIGWKRRLTGLEDDMRTDESEEEKSFWHMKVLPILHELESEDNVESLCLACTKLYQVLNEGNMLGKRFKRRSMLLKTLYKLVEIDSDPLCLKLAKIILSMKVDGKNLLGACKLAFKVCRNGINDYLIQNDTLLDCLLEVLRTEDLQKNNEALLYCLGAIKFMSGNAVLLNEMVNKGAVEMLLQLMKQINSIKENDSHFSSLGHLLVQLTATLRNLADLPQTRCQLVCSGAVSELCVALEQRMNDKDVCTYIVRIFSKLSSYNDFCAALADCSRCYILFLALLNKHQKQQDLVIRIIFILGNLTAKNNQAREQFFKEEGSVNTLMSLFQTYHELDLKEEKWYHERGREEKKNPQHPSKAEDVLIKLIRVLANLSIHPSVGAALAAAHHVVELLVTVLEYKSIEVCEELVINAATTINNLSFYKVKSSAVQDKKLRIAEMLLKLLMSNNMDGVVEAVRVFGNLSQYHEICDFIIQKKIHKFVIALLDAKNQDVCFSACGVLLNLTVDKDRRALLMEEGGIGKLVDCLRDFGPADLQLACLICKTLWNYSENITSAASCFGEDTDTLLMLLTSLLDEELALGYGLDRGDHHKLYWEMEFKPVAEKLLERIQTHRSSVSAAIITAF", "length": 851 }, "evidence": [ { "id": "P0C6R2", "url": "https://omabrowser.org/oma/group/P0C6R2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AE64-1", "protein_name": "Armadillo repeat containing 2", "gene_name": "Armc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRRSALTWTGGEAGFAGSGRAAVRAGGCFYEDHSNLKGKMLSSSEQKLDKLDAFYRLPLAKQKTSAEIISEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSLHASSFELADPKPISGTRLRPLELKPKAPASPNTEEDANLSFPKAPVDPAKIRRISGARARFYRAASQGTLLPDRSPPAAHSKTPVESRDTVSVGSATAKRNGAHLTASSATRHLKNPPLLPCDQGFRETTEQEASLQPQLGSRGDPGKRRARASSCPSSSDLSRQETRTASRASLQEQEPELEVDETFWKTRIIPILHELEKEEDIEAMCAACTQLHRALEEARMLGKRFKRRSVLLKALYKLVDAGSDALSLKLAKLILALKVSGKNLLNICKLVFKISRSEKNDTLMQKDNILQSLLEVLRDEDLQSNTEAFLYCMGALKFISGSPGFLTEMVNKGTVEILVQLIKETTEDTEKHGACLPNSGHLLVQTTATLRNLVDSPLTRSKLLNIGAFPCLCTVMGQHMNDKDICTNIARVFSKLTSYRDCCAALVSYSRCYALFLSLLNKYQKNQDLVIRIVFILGNLTAKSNQARELFSGESGSVETLLTLFQNFYRLEESSPKLQRSGARPRAEAEDVLVKLTRVLANIAIHPCIGPVLAADPRVVGLLLTTLESKSLGDCEELVINTTAAINNLSFYQVKSSVLQHRKLYVAELLLKLLVSNNMDGILEAVRVFGNLSQDHDVCNFLMQKNVHKFLITLLEAKHQDICFSACGVLLNLTVDKDKRAVLKEGGGIKKLVDCLRDFGPGDWQLACLVCKTLWNFSENITNASECFGDDVTNTLLILLSTFLDEELALDSSFDQDLKSYHRLHWETEFKPVAQELLKRIQSHHTLLEPLPVPSF", "length": 895 }, "evidence": [ { "id": "P0C6R2", "url": "https://omabrowser.org/oma/group/P0C6R2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QBI9-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "armc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSIMELQQNKSDGVYMSTGHRRQTSAEIVSEARRSLRSLATQRPFTPQEKNRQLFGESSSRARDGRPPSAFSLHARHFEAPDSRPGSGTRLSPLEHKPRVSVSLDEDGGDDEAAHPKPPVERGGTRTGSGGSRARLLRATSVSKIPPMTPNAKNMSPEARIGGDQPDDGDNLHSADITEHKTKSSSETDLHKQRRPQIDVSSPSGSKPDADDSEDESVFWNTKVLPVLQEFESFAGGDAVSDEIVGQLCNSCNGLHDALAERGMLGRQCKKRSGILRILFRLIDVGSDRLNLTLAKLILALNVSGNNLLNICKLVFKISRNANNDALFLNGSILDSLVSLLQCEDVWSKGEAVLYCVGSLKLLSGNSALSRLLLDKGFIGVLMQLSKRLMHSPSATSANVNTHRSDGEGQQIITGHILVQVTAALRNIADQSESRPSFLSNKAFSTLCLILENHRNDLDVCINVARIFSKLSTYTECCHALAETPRCCSLFLELLGKHSRKQDLVVRLLFTLGNLTAKSTEAREQVYEEERGMDVLLDLFQAYQNTSSPPEQRLSPEREDVLVKLIRLLANLAIHPTVGTALAANTLCVQLLLEVLECRSVQESEELVINAVATINNLSFYPSQSSVIRSQHTHISQLLLKLLLGSSMDAVLEATRVFGNLSQIKDVRRFVMQHKVEQFVITLLDSKSPDVCFSACGVLINLSADPDNRAMLSAEGAVQKLVDCLRDFGPQDWHLAAVVCQTLWNCSLDGELQHAQELLEILRLYTDREALQWPSEDGVRQVQEARWELLFLPVAERLRQRLHIENTTGIIQ", "length": 812 }, "evidence": [ { "id": "P0C6R2", "url": "https://omabrowser.org/oma/group/P0C6R2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3URY6-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "Armc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSNDQKLEKLDSFYRPPVSKQRTSAEIISEARNALRTVRTQRPFTPREDQRKLFGPASSRSPENRPPSSFSLHASSFELSDSKPISGTRLRPLELKPKAPASPGTEDACLSFPKAPLDPAKIRKISGARARFYRAASQGMLLPDRSPPAAHSKTVDESSKPVSVGSSTARRNGTHLTASSATGQLKSPPLLTCDQGFQETTEQEVSLLSQLRRGGDPGKRRARASSCPSSSDLSRKETRAASRASSQEQETDTEVDEVFWKARIVPILHELENEEDIEEMCAACTQLHRTLEEARMLGKKFKRRTVLLKALYKLVDADSDPLSLKLAKLILALKVSGKNLLNVCKLIFKISRNEKNDTLMQEDNILESLLEVLRAEELQSNTEAFLYCMGALKFVSGSPGFLTEMVNKGAVEILAQLIKEMTEDTEKHGVCLPDSGHLLVQTTATLRNLVDSPLTRSKLLNMGAFPHLCTVMEQHADDKDICTNIARIFSKLTSYRDCCAALASYSRCYALFLSLLNKYQKNQDLVIRIVFILGNLTAKSNQARELFSRETGSVETLLTLFQSFYHHKENSPKLQLSEAKPQAEAEDVLVKLTRVLANIAIHPRIGPVLAANPRVVGLLLRTLESKSLGDCEELVINTIAAINNLSFYQVKSSVLQHRKLYVAELLLRLLVSNNMERILEAVRVFGNLSQDHDVCNFLMQKNVHKFMITLLEAKHQDICFSACGVLLNLTVDKEKRAILKEGGGIKKLVDCLRDFGPSDWQLACLVCKTLWNFSENITNASECFGDDVANTLLILLSTFLDEELALNGSFDQDLESYHRLHWETEFKPVAQQLLQRIQSHHSLLEPLPVPSF", "length": 854 }, "evidence": [ { "id": "P0C6R2", "url": "https://omabrowser.org/oma/group/P0C6R2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IR94-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "Dmel\\CG32668", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5694530", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5694530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9769735", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769735", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9769743", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769743", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005227696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SHY4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQG7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1E8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1E8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1E8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5W1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5W1-1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHIKLSTCFFLCLWPCSFSAIRRYYLGAVELSWDYMQSELLSELHVNTRFPPRVPKPFPFNTSVMYRKTVFVEFTDQLFNIAKPRPPWMGLLGPTIQAEVYDTVVITFKNMASHPVSLHAIGVSYWKSSEGAAYEDETSQREKEDDKVIPGKSHTYVWQILKENGPTASDPPCLTYSYLSHVDLVKDVNSGLIGALLICREGTLIKERTQTLHKFVLLFAVFDEGKSWHSGKNESLTRVMDSASALHTINGYINRSLPGLIGCHKKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTVLMDCGQFLLFCRISSHQHDGMEAYVKVDSCPEEPRLWMKNNQEEDYDDGLDDSDMDVVRFDGDSAPPFIQMRSVAKKHPKTWVHYIAAEEDDWDYAPSVLTTSDRSYKSLYLNHGPQRIGRKYRKVRFIAYTDGTFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHSGRFPKGVKHLKDMPILPGEVFKYKWTVTVEDGPTKSDPRCLTRYYSSFINLEKDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENKSWYLTENIQRFLPNGVQPQDPEFQVSNVMHSINGYVFDSLQLSVCLHEVAYWYILSVGAQIDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDFRNRGMTALLKVDSCDRNVGDYYDTYEDIPTLLSDDNVIEPRSFSKNSRYPSTRQKQFKPTMTPENDMEKIDPQSGEKMQLLTEQSVSSSDLLMLLGQNPTPHRLSLSDLQETRNEATDHLPGPTERIKGPSPSEVAHLRPELHHSGERVFTQEPELPVRLNENLGTTIMAELNKLNLKISSSSNNLMPLPTIPSDKLSAGTKKTGSFGPPNMPVNFNSQLGAIVFGKNLSHVIGSRVPLGLSKEDNNSKLLEAALMNSQESSLGENALSLESDRLFKEERVHGPVSLNKDDALFKVNISLVKTDKAPANSTTNRKTHIDDPTVLIENSTSVWQDIVIDSNTNFQEVTSLIHDELFMHKNTTSFGLSHMSNKTTSSKKREMIHQEKEGPKPLDTKYPDTPFFKTLFLPDSTNVIKRTHDKNSLSSGQRPSPKQLTSSVSENSVKDQNVLSEKNKAVAGEDEFSNNTSLKEMIFPNTKSIVLTNLANVQENDTDNQGKKSQEETEKKETLIPENTVLPQVYTVIGTKNFLKNLFSLSTKQNVRGLDEETYTPGLQDNRSLSDSAKRARIHAAHFSKGRVEANVEGLGNQTKQMVEKSPSTTKLSPIPSQQDAVPHRDKRGLKQSRLPREEVKLERGVTLNDTSTQWSKSMKHLTQGTFTQIEHNKMEKRTITQSFLPDCSLRSHRSIRPTDVTKIPPQHNSSHPPASTYGYNLGASHSGVQETSHFLHGAKKNNLSLAFLTLEVIGSQRKSSTPGKQATNPLMYKKLENMFLLKPGLSEASGKVVHQEDLPTKTSKVSPAHLDLREEIFLQKTQGLVKLNKVYRTGKVPSLKWTTESSEEIPSKLLGLLAWDNQSATLIPKEDWKSLERSHKLTSLKTKDITLPLDPSENYYSIAVTNEGEDKAQREAPWPKQGGTGRVCCQNPPILKRHQREITLTTFQPEPDKTDYDDTLSIETKREDFDIYGEDENQDPRSFQKRTRHYFIAAVERLWDYGMSRSPYALRNRSQNGGVPQFKKVVFEEFTDGSFTQAIYRGQLNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYNGDQRQGAEPRKKFVKPNETQSYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDLHSGLIGPILICRVDTLSAAHGRQVTIQEFALFFTIFDETKSWYFAENMARNCGAPCHVQPEDPTFQEKYRFHAINGYVMDTLPGLVMAQHQRIRWYLLSMGSNENIHSIHFSGHVFTVRKTEEYKMAVYNLYPGVFETVEMLPSKVGTWRIECLIGEHLQAGMSTLFLVYSKECQIPLGMASGRIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPSPWIKVDLLAPMIIHSILTQGARQKFSSLYISQFIIMYSLDGQRWQGYRGNSTGTLMVFFGNVDSSGVKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCNMPLGMENKAISDTQITASSHLRNMFATWSPSQARLNLQGRTNAWRPQVNNPKEWLQVDFQKTMRVTGITTQGVKSLLTSMYVKEFLISSSQDGHNWTPFLQNGKVKVFQGNQDSFTPVVNALDPPLFTRFLRIHPRSWAHHIALRLELLGCEAQQQY", "length": 2323, "header": "tr|G5E5W1-1|G5E5W1_BOVIN Isoform 1 of Coagulation factor VIII OS=Bos taurus OX=9913 GN=F8 PE=3 SV=1 CANONICAL=G5E5W1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SHY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHY4/entry", "sequence": { "sequence": "MHIKLSTCFFLCLWPCSFSAIRRYYLGAVELSWDYMQSELLSELHVNTRFPPRVPKPFPFNTSVMYRKTVFVEFTDQLFNIAKPRPPWMGAAYEDETSQREKEDDKVIPGKSHTYVWQILKENGPTASDPPCLTYSYLSHVDLVKDVNSGLIGALLICREGTLIKERTQTLHKFVLLFAVFDEGKSWHSGKNESLTRVMDSASALHTINGYINRSLPGLIGCHKKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTVLMDCGQFLLFCRISSHQHDGMEAYVKVDSCPEEPRLWMKNNQEEDYDDGLDDSDMDVVRFDGDSAPPFIQMRSVAKKHPKTWVHYIAAEEDDWDYAPSVLTTSDRSYKSLYLNHGPQRIGRKYRKVRFIAYTDGTFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHSGRFPKGVKHLKDMPILPGEVFKYKWTVTVEDGPTKSDPRCLTRYYSSFINLEKDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENKSWYLTENIQRFLPNGVQPQDPEFQVSNVMHSINGYVFDSLQLSVCLHEVAYWYILSVGAQIDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDFRNRGMTALLKVDSCDRNVGDYYDTYEDIPTLLSDDNVIEPRSFSKNSRYPSTRQKQFKPTMTPENDMEKIDPQSGEKMQLLTEQSVSSSDLLMLLGQNPTPHRLSLSDLQETRNEATDHLPGPTERIKGPSPSEVAHLRPELHHSGERVFTQEPELPVRLNENLGTTIMAELNKLNLKISSSSNNLMPLPTIPSDKLSAGTKKTGSFGPPNMPVNFNSQLGAIVFGKNLSHVIGSRVPLGLSKEDNNSKLLEAALMNSQESSLGENALSLESDRLFKEERVHGPVSLNKDDALFKVNISLVKTDKAPANSTTNRKTHIDDPTVLIENSTSVWQDIVIDSNTNFQEVTSLIHDELFMHKNTTSFGLSHMSNKTTSSKKREMIHQEKEGPKPLDTKYPDTPFFKTLFLPDSTNVIKRTHDKNSLSSGQRPSPKQLTSSVSENSVKDQNVLSEKNKAVAGEDEFSNNTSLKEMIFPNTKSIVLTNLANVQENDTDNQGKKSQEETEKKETLIPENTVLPQVYTVIGTKNFLKNLFSLSTKQNVRGLDEETYTPGLQDNRSLSDSAKRARIHAAHFSKGRVEANVEGLGNQTKQMVEKSPSTTKLSPIPSQQDAVPHRDKRGLKQSRLPREEVKLERGVTLNDTSTQWSKSMKHLTQGTFTQIEHNKMEKRTITQSFLPDCSLRSHRSIRPTDVTKIPPQHNSSHPPASTYGYNLGASHSGVQETSHFLHGAKKNNLSLAFLTLEVIGSQRKSSTPGKQATNPLMYKKLENMFLLKPGLSEASGKVVHQEDLPTKTSKVSPAHLDLREEIFLQKTQGLVKLNKVYRTGKVPSLKWTTESSEEIPSKLLGLLAWDNQSATLIPKEDWKSLERSHKLTSLKTKDITLPLDPSENYYSIAVTNEGEDKAQREAPWPKQGGTGRVCCQNPPILKRHQREITLTTFQPEPDKTDYDDTLSIETKREDFDIYGEDENQDPRSFQKRTRHYFIAAVERLWDYGMSRSPYALRNRSQNGGVPQFKKVVFEEFTDGSFTQAIYRGQLNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYNGDQRQGAEPRKKFVKPNETQSYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDLHSGLIGPILICRVDTLSAAHGRQVTIQEFALFFTIFDETKSWYFAENMARNCGAPCHVQPEDPTFQEKYRFHAINGYVMDTLPGLVMAQHQRIRWYLLSMGSNENIHSIHFSGHVFTVRKTEEYKMAVYNLYPGVFETVEMLPSKVGTWRIECLIGEHLQAGMSTLFLVYSKECQIPLGMASGRIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPSPWIKVDLLAPMIIHSILTQGARQKFSSLYISQFIIMYSLDGQRWQGYRGNSTGTLMVFFGNVDSSGVKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCNMPLGMENKAISDTQITASSHLRNMFATWSPSQARLNLQGRTNAWRPQVNNPKEWLQVDFQKTMRVTGITTQGVKSLLTSMYVKEFLISSSQDGHNWTPFLQNGKVKVFQGNQDSFTPVVNALDPPLFTRFLRIHPRSWAHHIALRLELLGCEAQQQY", "length": 2282, "header": "tr|A0AAA9SHY4-1|G5E5W1_BOVIN Computationally mapped isoform of Coagulation factor VIII OS=Bos taurus OX=9913 GN=F8 PE=3 SV=1 CANONICAL=G5E5W1-1" }, "locus": { "chromosome": "X", "start_pos": 36154902, "end_pos": 36017293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128102.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128102.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083506.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083506.1" } ] } }, { "isoform_ac": "A0AAA9SQG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQG7/entry", "sequence": { "sequence": "MHIKLSTCFFLCLWPCSFSAIRRYYLGAVELSWDYMQSELLSELHVNTRFPPRVPKPFPFNTSVMYRKTVFVEFTDQLFNIAKPRPPWMGLLGPTIQAEVYDTVVITFKNMASHPVSLHAIGVSYWKSSEGAAYEDETSQREKEDDKVIPGKSHTYVWQILKENGPTASDPPCLTYSYLSHVDLVKDVNSGLIGALLICREGTLIKERTQTLHKFVLLFAVFDEGKSWHSGKNESLTRVMDSASALHTINGYINRSLPGLIGCHKKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTVLMDCGQFLLFCRISSHQHDGMEAYVKVDSCPEEPRLWMKNNQEEDYDDGLDDSDMDVVRFDGDSAPPFIQMRSVAKKHPKTWVHYIAAEEDDWDYAPSVLTTSDRSYKSLYLNHGPQRIGRKYRKVRFIAYTDGTFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHSGRFPKGVKHLKDMPILPGEVFKYKWTVTVEDGPTKSDPRCLTRYYSSFINLEKDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENKSWYLTENIQRFLPNGVQPQDPEFQVSNVMHSLWVLGCHNSDFRNRGMTALLKVDSCDRNVGDYYDTYEDIPTLLSDDNVIEPRSFSKNSRYPSTRQKQFKPTMTPENDMEKIDPQSGEKMQLLTEQSVSSSDLLMLLGQNPTPHRLSLSDLQETRNEATDHLPGPTERIKGPSPSEVAHLRPELHHSGERVFTQEPELPVRLNENLGTTIMAELNKLNLKISSSSNNLMPLPTIPSDKLSAGTKKTGSFGPPNMPVNFNSQLGAIVFGKNLSHVIGSRVPLGLSKEDNNSKLLEAALMNSQESSLGENALSLESDRLFKEERVHGPVSLNKDDALFKVNISLVKTDKAPANSTTNRKTHIDDPTVLIENSTSVWQDIVIDSNTNFQEVTSLIHDELFMHKNTTSFGLSHMSNKTTSSKKREMIHQEKEGPKPLDTKYPDTPFFKTLFLPDSTNVIKRTHDKNSLSSGQRPSPKQLTSSVSENSVKDQNVLSEKNKAVAGEDEFSNNTSLKEMIFPNTKSIVLTNLANVQENDTDNQGKKSQEETEKKETLIPENTVLPQVYTVIGTKNFLKNLFSLSTKQNVRGLDEETYTPGLQDNRSLSDSAKRARIHAAHFSKGRVEANVEGLGNQTKQMVEKSPSTTKLSPIPSQQDAVPHRDKRGLKQSRLPREEVKLERGVTLNDTSTQWSKSMKHLTQGTFTQIEHNKMEKRTITQSFLPDCSLRSHRSIRPTDVTKIPPQHNSSHPPASTYGYNLGASHSGVQETSHFLHGAKKNNLSLAFLTLEVIGSQRKSSTPGKQATNPLMYKKLENMFLLKPGLSEASGKVVHQEDLPTKTSKVSPAHLDLREEIFLQKTQGLVKLNKVYRTGKVPSLKWTTESSEEIPSKLLGLLAWDNQSATLIPKEDWKSLERSHKLTSLKTKDITLPLDPSENYYSIAVTNEGEDKAQREAPWPKQGGTGRVCCQNPPILKRHQREITLTTFQPEPDKTDYDDTLSIETKREDFDIYGEDENQDPRSFQKRTRHYFIAAVERLWDYGMSRSPYALRNRSQNGGVPQFKKVVFEEFTDGSFTQAIYRGQLNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYNGDQRQGAEPRKKFVKPNETQSYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDLHSGLIGPILICRVDTLSAAHGRQVTIQEFALFFTIFDETKSWYFAENMARNCGAPCHVQPEDPTFQEKYRFHAINGYVMDTLPGLVMAQHQRIRWYLLSMGSNENIHSIHFSGHVFTVRKTEEYKMAVYNLYPGVFETVEMLPSKVGTWRIECLIGEHLQAGMSTLFLVYSKECQIPLGMASGRIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPSPWIKVDLLAPMIIHSILTQGARQKFSSLYISQFIIMYSLDGQRWQGYRGNSTGTLMVFFGNVDSSGVKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCNMPLGMENKAISDTQITASSHLRNMFATWSPSQARLNLQGRTNAWRPQVNNPKEWLQVDFQKTMRVTGITTQGVKSLLTSMYVKEFLISSSQDGHNWTPFLQNGKVKVFQGNQDSFTPVVNALDPPLFTRFLRIHPRSWAHHIALRLELLGCEAQQQY", "length": 2253, "header": "tr|A0AAA9SQG7-1|G5E5W1_BOVIN Computationally mapped isoform of Coagulation factor VIII OS=Bos taurus OX=9913 GN=F8 PE=3 SV=1 CANONICAL=G5E5W1-1" }, "locus": { "chromosome": "X", "start_pos": 36154902, "end_pos": 36017293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089546.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089546.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088583.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088583.1" } ] } }, { "isoform_ac": "A0AAA9T1E8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1E8/entry", "sequence": { "sequence": "MTPARLRRGRTRSGAPPPSARGGFRFPPRVPKPFPFNTSVMYRKTVFVEFTDQLFNIAKPRPPWMGLLGPTIQAEVYDTVVITFKNMASHPVSLHAIGVSYWKSSEGAAYEDETSQREKEDDKVIPGKSHTYVWQILKENGPTASDPPCLTYSYLSHVDLVKDVNSGLIGALLICREGTLIKERTQTLHKFVLLFAVFDEGKSWHSGKNESLTRVMDSASALHTINGYINRSLPGLIGCHKKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTVLMDCGQFLLFCRISSHQHDGMEAYVKVDSCPEEPRLWMKNNQEEDYDDGLDDSDMDVVRFDGDSAPPFIQMRSVAKKHPKTWVHYIAAEEDDWDYAPSVLTTSDRSYKSLYLNHGPQRIGRKYRKVRFIAYTDGTFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHSGRFPKGVKHLKDMPILPGEVFKYKWTVTVEDGPTKSDPRCLTRYYSSFINLEKDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENKSWYLTENIQRFLPNGVQPQDPEFQVSNVMHSINGYVFDSLQLSVCLHEVAYWYILSVGAQIDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDFRNRGMTALLKVDSCDRNVGDYYDTYEDIPTLLSDDNVIEPRSFSKNSRYPSTRQKQFKPTMTPENDMEKIDPQSGEKMQLLTEQSVSSSDLLMLLGQNPTPHRLSLSDLQETRNEATDHLPGPTERIKGPSPSEVAHLRPELHHSGERVFTQEPELPVRLNENLGTTIMAELNKLNLKISSSSNNLMPLPTIPSDKLSAGTKKTGSFGPPNMPVNFNSQLGAIVFGKNLSHVIGSRVPLGLSKEDNNSKLLEAALMNSQESSLGENALSLESDRLFKEERVHGPVSLNKDDALFKVNISLVKTDKAPANSTTNRKTHIDDPTVLIENSTSVWQDIVIDSNTNFQEVTSLIHDELFMHKNTTSFGLSHMSNKTTSSKKREMIHQEKEGPKPLDTKYPDTPFFKTLFLPDSTNVIKRTHDKNSLSSGQRPSPKQLTSSVSENSVKDQNVLSEKNKAVAGEDEFSNNTSLKEMIFPNTKSIVLTNLANVQENDTDNQGKKSQEETEKKETLIPENTVLPQVYTVIGTKNFLKNLFSLSTKQNVRGLDEETYTPGLQDNRSLSDSAKRARIHAAHFSKGRVEANVEGLGNQTKQMVEKSPSTTKLSPIPSQQDAVPHRDKRGLKQSRLPREEVKLERGVTLNDTSTQWSKSMKHLTQGTFTQIEHNKMEKRTITQSFLPDCSLRSHRSIRPTDVTKIPPQHNSSHPPASTYGYNLGASHSGVQETSHFLHGAKKNNLSLAFLTLEVIGSQRKSSTPGKQATNPLMYKKLENMFLLKPGLSEASGKVVHQEDLPTKTSKVSPAHLDLREEIFLQKTQGLVKLNKVYRTGKVPSLKWTTESSEEIPSKLLGLLAWDNQSATLIPKEDWKSLERSHKLTSLKTKDITLPLDPSENYYSIAVTNEGEDKAQREAPWPKQGGTGRVCCQNPPILKRHQREITLTTFQPEPDKTDYDDTLSIETKREDFDIYGEDENQDPRSFQKRTRHYFIAAVERLWDYGMSRSPYALRNRSQNGGVPQFKKVVFEEFTDGSFTQAIYRGQLNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYNGDQRQGAEPRKKFVKPNETQSYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDLHSGLIGPILICRVDTLSAAHGRQVTIQEFALFFTIFDETKSWYFAENMARNCGAPCHVQPEDPTFQEKYRFHAINGYVMDTLPGLVMAQHQRIRWYLLSMGSNENIHSIHFSGHVFTVRKTEEYKMAVYNLYPGVFETVEMLPSKVGTWRIECLIGEHLQAGMSTLFLVYSKECQIPLGMASGRIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPSPWIKVDLLAPMIIHSILTQGARQKFSSLYISQFIIMYSLDGQRWQGYRGNSTGTLMVFFGNVDSSGVKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCNMPLGMENKAISDTQITASSHLRNMFATWSPSQARLNLQGRTNAWRPQVNNPKEWLQVDFQKTMRVTGITTQGVKSLLTSMYVKEFLISSSQDGHNWTPFLQNGKVKVFQGNQDSFTPVVNALDPPLFTRFLRIHPRSWAHHIALRLELLGCEAQQQY", "length": 2299, "header": "tr|A0AAA9T1E8-1|G5E5W1_BOVIN Computationally mapped isoform of Coagulation factor VIII OS=Bos taurus OX=9913 GN=F8 PE=3 SV=1 CANONICAL=G5E5W1-1" }, "locus": { "chromosome": "X", "start_pos": 36154902, "end_pos": 36013610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116174.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116174.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090405.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090405.1" } ] } }, { "isoform_ac": "G5E5W1-1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1/entry", "sequence": { "sequence": "MHIKLSTCFFLCLWPCSFSAIRRYYLGAVELSWDYMQSELLSELHVNTRFPPRVPKPFPFNTSVMYRKTVFVEFTDQLFNIAKPRPPWMGLLGPTIQAEVYDTVVITFKNMASHPVSLHAIGVSYWKSSEGAAYEDETSQREKEDDKVIPGKSHTYVWQILKENGPTASDPPCLTYSYLSHVDLVKDVNSGLIGALLICREGTLIKERTQTLHKFVLLFAVFDEGKSWHSGKNESLTRVMDSASALHTINGYINRSLPGLIGCHKKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTVLMDCGQFLLFCRISSHQHDGMEAYVKVDSCPEEPRLWMKNNQEEDYDDGLDDSDMDVVRFDGDSAPPFIQMRSVAKKHPKTWVHYIAAEEDDWDYAPSVLTTSDRSYKSLYLNHGPQRIGRKYRKVRFIAYTDGTFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHSGRFPKGVKHLKDMPILPGEVFKYKWTVTVEDGPTKSDPRCLTRYYSSFINLEKDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENKSWYLTENIQRFLPNGVQPQDPEFQVSNVMHSINGYVFDSLQLSVCLHEVAYWYILSVGAQIDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDFRNRGMTALLKVDSCDRNVGDYYDTYEDIPTLLSDDNVIEPRSFSKNSRYPSTRQKQFKPTMTPENDMEKIDPQSGEKMQLLTEQSVSSSDLLMLLGQNPTPHRLSLSDLQETRNEATDHLPGPTERIKGPSPSEVAHLRPELHHSGERVFTQEPELPVRLNENLGTTIMAELNKLNLKISSSSNNLMPLPTIPSDKLSAGTKKTGSFGPPNMPVNFNSQLGAIVFGKNLSHVIGSRVPLGLSKEDNNSKLLEAALMNSQESSLGENALSLESDRLFKEERVHGPVSLNKDDALFKVNISLVKTDKAPANSTTNRKTHIDDPTVLIENSTSVWQDIVIDSNTNFQEVTSLIHDELFMHKNTTSFGLSHMSNKTTSSKKREMIHQEKEGPKPLDTKYPDTPFFKTLFLPDSTNVIKRTHDKNSLSSGQRPSPKQLTSSVSENSVKDQNVLSEKNKAVAGEDEFSNNTSLKEMIFPNTKSIVLTNLANVQENDTDNQGKKSQEETEKKETLIPENTVLPQVYTVIGTKNFLKNLFSLSTKQNVRGLDEETYTPGLQDNRSLSDSAKRARIHAAHFSKGRVEANVEGLGNQTKQMVEKSPSTTKLSPIPSQQDAVPHRDKRGLKQSRLPREEVKLERGVTLNDTSTQWSKSMKHLTQGTFTQIEHNKMEKRTITQSFLPDCSLRSHRSIRPTDVTKIPPQHNSSHPPASTYGYNLGASHSGVQETSHFLHGAKKNNLSLAFLTLEVIGSQRKSSTPGKQATNPLMYKKLENMFLLKPGLSEASGKVVHQEDLPTKTSKVSPAHLDLREEIFLQKTQGLVKLNKVYRTGKVPSLKWTTESSEEIPSKLLGLLAWDNQSATLIPKEDWKSLERSHKLTSLKTKDITLPLDPSENYYSIAVTNEGEDKAQREAPWPKQGGTGRVCCQNPPILKRHQREITLTTFQPEPDKTDYDDTLSIETKREDFDIYGEDENQDPRSFQKRTRHYFIAAVERLWDYGMSRSPYALRNRSQNGGVPQFKKVVFEEFTDGSFTQAIYRGQLNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYNGDQRQGAEPRKKFVKPNETQSYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDLHSGLIGPILICRVDTLSAAHGRQVTIQEFALFFTIFDETKSWYFAENMARNCGAPCHVQPEDPTFQEKYRFHAINGYVMDTLPGLVMAQHQRIRWYLLSMGSNENIHSIHFSGHVFTVRKTEEYKMAVYNLYPGVFETVEMLPSKVGTWRIECLIGEHLQAGMSTLFLVYSKECQIPLGMASGRIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPSPWIKVDLLAPMIIHSILTQGARQKFSSLYISQFIIMYSLDGQRWQGYRGNSTGTLMVFFGNVDSSGVKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCNMPLGMENKAISDTQITASSHLRNMFATWSPSQARLNLQGRTNAWRPQVNNPKEWLQVDFQKTMRVTGITTQGVKSLLTSMYVKEFLISSSQDGHNWTPFLQNGKVKVFQGNQDSFTPVVNALDPPLFTRFLRIHPRSWAHHIALRLELLGCEAQQQY", "length": 2323, "header": "tr|G5E5W1-1|G5E5W1_BOVIN Isoform 1 of Coagulation factor VIII OS=Bos taurus OX=9913 GN=F8 PE=3 SV=1 CANONICAL=G5E5W1-1" }, "locus": { "chromosome": "X", "start_pos": 36154902, "end_pos": 36017293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036726.5", "url": "https://www.ensembl.org/id/ENSBTAT00000036726.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036581.4", "url": "https://www.ensembl.org/id/ENSBTAP00000036581.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 167, "start_aa": "Thr", "end_pos": 167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr167", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-BTA-163841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163841", "resource": "Reactome", "description": "Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation" }, { "id": "R-BTA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-BTA-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" }, { "id": "R-BTA-9769735", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769735", "resource": "Reactome", "description": "Initiation of coagulation cascade" }, { "id": "R-BTA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" }, { "id": "R-BTA-9769743", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769743", "resource": "Reactome", "description": "Amplification and propagation of coagulation cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZEB1-1", "protein_name": "Coagulation factor VIII", "gene_name": "F8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAARGLCFFLSLCALCSCATRKYYLGAVELPWDYVSGGASGAQRSDSRFPPGTPAPSAHVVHTKTVFVEYMDRFFHTAKPRPLWMGLLGPTIWTEVHDTVVITLKNMASHPVSLHAVGMSFWKASEGAAYDDHSSPAEKDDDKVLPGESHTYAWQVLGESGPMASDPPCLTYAYLSHVDLVRDLNSGLVGALLVCKEGRLSADRTRMPPHFVLLFAVFDEGRSWHAATRDPASTEAQPTVHTVNGYTNRTLPGLTGCRGTSVYWHVMAVGTTPDIHSILLEGHTFSVRSHRQASLEISPMTLLTAQTWLMDLGRFLLFCHISSHRHGGMEAYVQVDNCPEAPQGQGKRDEDTEDYDDLDSEMDVFTWDPDAAPFVQVRSAAKRHPKTWVHYIAAEEGDWDYAPAAATLEDGSLRNRYLGRGPGRIGSKYKKVRFVAYTDGTFHTREATPREAGLLGPLLYGEVGDSLLIVFKNRASRAYNIHPHGIRDVGAVHAGRLPRGVKHVKDLPIRPGETFKYRWTLTAEDGPARSDARCVTRYYASAVDPERDLASGLIGPLLICCKESVDQRGNQMMSDERNVILFSVFDENRSWYISENMRRFLPDEAHVQLQDPEFEASNLMHSINGYVFDSLELRVCLHEVAAWHVLSVGAQTDFLSVFFSGHTFRHRAVYADTLTVFPHSGVTVFMSMDNPGVWVLGCHNPDFRESGMTALLKVSSCDEGVSDYYGETYEGVLAPLANDNAVDPRSFSQNSNHLHSRKKKSNTPMRFPLSHPTQHGSFWSDSQGDVHDAVHRAHSPAAAHSNEGPAEAAQLEPKPHPGEKMALPPSWLRAKRSLVTTMEAKRKKLDLQVQVSGLPDDRTTAVVAPDDPMAACKKAGSSGFPDESSPAALGKKMYPRIRPHGPLSIIEGNRDSNSSDSTLMYRLGSPPGDATSWTENRRGLGEKRSHRVAFLARGNTLLSDVDEKSHAPGPTSVGNSTAAVQDTILEICSEILEVTPPIHDRILSDKSATYLRPHRTPDRITSTERKDIRHKKDGDLVPQDADDTSAPFSEAPFLSESTDWLKEANGDNSAKPEQEPSPEQLVYLMYIKCMENQSFSSEKNKMIAGQGGFTKNTGLEDTVFPRKTSVFLTTVAKRQESGRHNQENIPQAVTEKEAPIEEKGALPQVHIATGSKNFPRDMFVLGTGQNINLHEETYVPVHKNVPWTRNPTDTRQIPMVHFFKKRKEEETNSGGLVNKTRETVRNYPSQKNSVARRREQASGRIKASARWLPDVNRSIQSLLKQIDHRKERKKFIIESRSADSSGTKSPTQTNHSPSHVVKMSAFPPRDIRRIESRDSSQVWVSSYAYDFETGSSRIRESSPFLNETETDNPSLAVPPRERFVRRGRFASPEKVNTHSAPCDKPENVVSSEPVSPGEAVTVALPPHVSTQEEEPLPAGSSCERRGHVDLFLEISLQRTRGPVERSRGRRSGGDTEGHTENPGKTPSPLPQMPKDQRGSEAGYPKICRWRDGTVLPPRPHNLSLGAKKKPNLPRREATRVEQGEAPSLVSPEPLVLRRRPREASTLLPGGEMREDDGDGVTAEYDDDDDVMAEYDDDAVTVDTPEDFDIYGEEAGQGPRGFQQKTRHYFIAAVEELWDYGVRVSPGALGDRAWSGDAARFRKVVFREFTDGSFTQRVHRGELDAHLGLLGPYIRAEVEDNIVVTFRNQASRPYSFYSSLVSYPEADGGAAPRSNFVRPNETKTYFWRVRPHMAPTDGEFDCKAWAYFSDVDLERDLHSGLIGPLLVCHASTLHPSHARPLAVQEFALLFAVFDETKSWYCAENLDRKCRPPRGTPAGDPAWREEYRFHAVNGYVADALLGLVMAEGRRTRWHLLSMGDPGHAQSVHFSAHSVTVRDGGEHRTAVCNLYPGVFTTVEMLPSRAGIWRVESLVGEHLQAGMSALFLVYSTRCQVPLGMASGYIRDSQITASGYHGLWTPQLARLHNAGSVNAWSAKEPFAWIKVDLLAPMILHGIETQGARHRLSSLYVSQFIIMYSLDGKQWLSYRGNSTGSLMVFFGNVDASTVRHNRFDPPIVARYIRVHPTHASIRTALRMELLGCDLNSCSAPLGMESGWISDTQVTASSHLSTTFSAWPPALARLHLRGGANAWRPQVNDPTQWLQVDLQRTVKVTGVVTQGARSLLTAMFVKKFLVSTSQDGRHWTHVLQDGKVKVFQGNRDASTPMVNSLHPPRFTRYLRIHPQVWERQIALRLEILGCEAQQLD", "length": 2258 }, "evidence": [ { "id": "G5E5W1", "url": "https://omabrowser.org/oma/group/G5E5W1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7GL28-1", "protein_name": "Coagulation factor VIII", "gene_name": "F8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQLELSTCVFLCLLPLGFSAIRRYYLGAVELSWDYRQSELLRELHVDTRFPATAPGALPLGPSVLYKKTVFVEFTDQLFSVARPRPPWMGLLGPTIQAEVYDTVVVTLKNMASHPVSLHAVGVSFWKSSEGAEYEDHTSQREKEDDKVLPGKSQTYVWQVLKENGPTASDPPCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLTRERTQNLHEFVLLFAVFDEGKSWHSARNDSWTRAMDPAPARAQPAMHTVNGYVNRSLPGLIGCHKKSVYWHVIGMGTSPEVHSIFLEGHTFLVRHHRQASLEISPLTFLTAQTFLMDLGQFLLFCHISSHHHGGMEAHVRVESCAEEPQLRRKADEEEDYDDNLYDSDMDVVRLDGDDVSPFIQIRSVAKKHPKTWVHYISAEEEDWDYAPAVPSPSDRSYKSLYLNSGPQRIGRKYKKARFVAYTDVTFKTRKAIPYESGILGPLLYGEVGDTLLIIFKNKASRPYNIYPHGITDVSALHPGRLLKGWKHLKDMPILPGETFKYKWTVTVEDGPTKSDPRCLTRYYSSSINLEKDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENQSWYLAENIQRFLPNPDGLQPQDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSVGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDLRNRGMTALLKVYSCDRDIGDYYDNYEDIPGFLLSGKNVIEPRSFAQNSRPPSASQKQFQTITSPEDDVELDPQSGERTQALEELSVPSGDGSMLLGQNPAPHGSSSSDLQEARNEADDYLPGARERNTAPSAAARLRPELHHSAERVLTPEPEKELKKLDSKMSSSSDLLKTSPTIPSDTLSAETERTHSLGPPHPQVNFRSQLGAIVLGKNSSHFIGAGVPLGSSEEDHESSLGENVSPVESDGIFEEERAHGPASLTKDDVLFKVNISLVKTNKARVYLKTNRKIHIDDAALLTENRASATFMDKNTTASGLNHVSNWIKGPLGKNPLSSERRPSPELLTSSGSGKSVKGQSFWAGENTVAVEEEELSKGKEMMLPNSELTFLTNSADVQGNDTHSQGKKSREEMERREKLVQEKVDLPQVYTATGTKNFLRNIFSPKSTEPSVEGFDGGSHAPVPQDSRSLNDSAERAGTHIAHFSAIREEAPLEAPGNRTGPGPRSAVPARVKRDLKQIRLPLEEIKPERGVVLNATSTRWSESSPILQGAKRNNLSLPFLTLEMAGGQGKISALGKSAAGPLASGKLEKAVLSSAGLSEASGKAEFLPKVRVHREDLLPQKTSNVSRAHGDLGQEIFLQKTRGPVNLNKVNRPGRTPSKLLGPPMPKEWESLEKSPKSTALRTKDIISLPLDRHESNHSIAAKNEGQAETQREAAWTKQGGPGRLCAPKPPVLRRHQRDISLPTFQPEEDKMDYDDIFSTETKGEDFDIYGEDENQDPRSFQKRTRHYFIAAVEQLWDYGMSESPRALRNRAQNGEVPRFKKVVFREFADGSFTQPSYRGELNKHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYPDDQEQGAEPRHNFVQPNETRTYFWKVQHHMAPTEDEFDCKAWAYFSDVDLEKDVHSGLIGPLLICRANTLNAAHGRQVTVQEFALFFTIFDETKSWYFTENVERNCRAPCHLQMEDPTLKENYRFHAINGYVMDTLPGLVMAQNQRIRWYLLSMGSNENIHSIHFSGHVFSVRKKEEYKMAVYNLYPGVFETVEMLPSKVGIWRIECLIGEHLQAGMSTTFLVYSKECQAPLGMASGRIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPHSWIKVDLLAPMIIHGIMTQGARQKFSSLYISQFIIMYSLDGRNWQSYRGNSTGTLMVFFGNVDASGIKHNIFNPPIVARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMQNKAISDSQITASSHLSNIFATWSPSQARLHLQGRTNAWRPRVSSAEEWLQVDLQKTVKVTGITTQGVKSLLSSMYVKEFLVSSSQDGRRWTLFLQDGHTKVFQGNQDSSTPVVNALDPPLFTRYLRIHPTSWAQHIALRLELLGCEAQQHV", "length": 2133 }, "evidence": [ { "id": "G5E5W1", "url": "https://omabrowser.org/oma/group/G5E5W1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P00451-1", "protein_name": "Coagulation factor VIII", "gene_name": "F8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQIELSTCFFLCLLRFCFSATRRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSFPFNTSVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNTGDYYEDSYEDISAYLLSKNNAIEPRSFSQNSRHPSTRQKQFNATTIPENDIEKTDPWFAHRTPMPKIQNVSSSDLLMLLRQSPTPHGLSLSDLQEAKYETFSDDPSPGAIDSNNSLSEMTHFRPQLHHSGDMVFTPESGLQLRLNEKLGTTAATELKKLDFKVSSTSNNLISTIPSDNLAAGTDNTSSLGPPSMPVHYDSQLDTTLFGKKSSPLTESGGPLSLSEENNDSKLLESGLMNSQESSWGKNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGPSLLIENSPSVWQNILESDTEFKKVTPLIHDRMLMDKNATALRLNHMSNKTTSSKNMEMVQQKKEGPIPPDAQNPDMSFFKMLFLPESARWIQRTHGKNSLNSGQGPSPKQLVSLGPEKSVEGQNFLSEKNKVVVGKGEFTKDVGLKEMVFPSSRNLFLTNLDNLHENNTHNQEKKIQEEIEKKETLIQENVVLPQIHTVTGTKNFMKNLFLLSTRQNVEGSYDGAYAPVLQDFRSLNDSTNRTKKHTAHFSKKGEEENLEGLGNQTKQIVEKYACTTRISPNTSQQNFVTQRSKRALKQFRLPLEETELEKRIIVDDTSTQWSKNMKHLTPSTLTQIDYNEKEKGAITQSPLSDCLTRSHSIPQANRSPLPIAKVSSFPSIRPIYLTRVLFQDNSSHLPAASYRKKDSGVQESSHFLQGAKKNNLSLAILTLEMTGDQREVGSLGTSATNSVTYKKVENTVLPKPDLPKTSGKVELLPKVHIYQKDLFPTETSNGSPGHLDLVEGSLLQGTEGAIKWNEANRPGKVPFLRVATESSAKTPSKLLDPLAWDNHYGTQIPKEEWKSQEKSPEKTAFKKKDTILSLNACESNHAIAAINEGQNKPEIEVTWAKQGRTERLCSQNPPVLKRHQREITRTTLQSDQEEIDYDDTISVEMKKEDFDIYDEDENQSPRSFQKKTRHYFIAAVERLWDYGMSSSPHVLRNRAQSGSVPQFKKVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKEPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY", 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"Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "G5E5W1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "G5E5W1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "G5E5W1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "G5E5W1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1" } ], "pmid": "" }, { "name": "blood coagulation, intrinsic pathway", "id": "GO:0007597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007597", "evidence": [ { "database": "UniProtKB", "id": "G5E5W1", "url": "https://www.uniprot.org/uniprotkb/G5E5W1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1006, "end_pos": 1008, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1018, "end_pos": 1020, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1036, "end_pos": 1038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1068, "end_pos": 1070, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1079, "end_pos": 1081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1172, "end_pos": 1174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1173, "end_pos": 1175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1198, "end_pos": 1200, "annotation": 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"https://www.ncbi.nlm.nih.gov/gene/519403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519403", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519403", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NWLEFKK", "url": "https://omabrowser.org/oma/group/NWLEFKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5R8", "url": "https://www.orthodb.org/?gene=G5E5R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15962", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15962", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15962:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15962:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18162", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18162", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21395", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21395", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193336", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193336", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SI88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SI88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5R8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELDHRTTGGLHAYPGPRSGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLAEVSKQVERELKGLHRSVGKLESNLDGYVPTSDSQRWKKSIKACLSRCQETIANLERWVKREMHVWREVFYRLERWADRLESGGGKYPVGSDPARHTVSVGVGGPEGYCQEADNYDYTVSPYAITSPPAAGQLPGQEEVEAQQYPPWGPGEDGQLSPGVDTQVFEDPREFLSHLEDYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKLKRFLRPPLPKTLEQLIQKGMEVQDGLEPAAEPTGPHPPAEEEAESLTPALTNESVASDRTQPE", "length": 396, "header": "tr|G5E5R8-1|G5E5R8_BOVIN Isoform 1 of Activity regulated cytoskeleton associated protein OS=Bos taurus OX=9913 GN=ARC PE=4 SV=1 CANONICAL=G5E5R8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SI88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI88/entry", "sequence": { "sequence": "MELDHRTTGGLHAYPGPRSGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLAEVSKQVERELKGLHRSVGKLESNLDGYVPTSDSQRWKKSIKACLSRCQETIANLERWVKREMHVWREVFYRLERWADRLESGGGKYPVGSDPARHTVSVGVGGPEGYCQEADNYDYTVSPYAITSPPAAGQLPGQEEVEAQQYPPWGPGEDGQLSPGVDTQVFEDPREFLSHLEDYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKLKRFLRPGNLCPWGSLRLPAKPCCGLARTPTAPATNTLVLAGHLCLQPKQAWLGAPRLRRPAPAGNSASPSVLRPASAASRPRFYFCI", "length": 420, "header": "tr|A0AAA9SI88-1|G5E5R8_BOVIN Computationally mapped isoform of Activity regulated cytoskeleton associated protein OS=Bos taurus OX=9913 GN=ARC PE=4 SV=1 CANONICAL=G5E5R8-1" }, "locus": { "chromosome": "14", "start_pos": 1744371, "end_pos": 1741364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130381.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130381.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085950.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085950.1" } ] } }, { "isoform_ac": "G5E5R8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R8/entry", "sequence": { "sequence": "MELDHRTTGGLHAYPGPRSGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLAEVSKQVERELKGLHRSVGKLESNLDGYVPTSDSQRWKKSIKACLSRCQETIANLERWVKREMHVWREVFYRLERWADRLESGGGKYPVGSDPARHTVSVGVGGPEGYCQEADNYDYTVSPYAITSPPAAGQLPGQEEVEAQQYPPWGPGEDGQLSPGVDTQVFEDPREFLSHLEDYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKLKRFLRPPLPKTLEQLIQKGMEVQDGLEPAAEPTGPHPPAEEEAESLTPALTNESVASDRTQPE", "length": 396, "header": "tr|G5E5R8-1|G5E5R8_BOVIN Isoform 1 of Activity regulated cytoskeleton associated protein OS=Bos taurus OX=9913 GN=ARC PE=4 SV=1 CANONICAL=G5E5R8-1" }, "locus": { "chromosome": "14", "start_pos": 1744556, "end_pos": 1744092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028836.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028836.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028836.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028836.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519403", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B294-1", "protein_name": "Activity regulated cytoskeleton associated protein", "gene_name": "ARC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELDHRTTGGLHAYPGPRGAPAAKPNVILQIGKCRAEMLEHVRRTHRHLLAEVSKQVERELKGLHRSVGKLESNLDGYVPTGDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESSGGKYPVGSDPARHTVSVGVGGPESYCPEADNYDYTVSPYAITPPPAAGELPGQEAVEAQQYPPWGPGEEGQSSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEYKQGSVKNWVEFKKEFLQYSEGALSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKLKRFLRPPLPKTLEQLIQKGMEVQDGLEQAAEPAGPRLPAEEEREALTPALTNESVASDRTQPE", "length": 396 }, "evidence": [ { "id": "G5E5R8", "url": "https://omabrowser.org/oma/group/G5E5R8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q63053-1", "protein_name": "Activity-regulated cytoskeleton-associated protein", "gene_name": "Arc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELDHMTTGGLHAYPAPRGGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLTEVSKQVERELKGLHRSVGKLENNLDGYVPTGDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESMGGKYPVGSEPARHTVSVGVGGPEPYCQEADGYDYTVSPYAITPPPAAGELPEQESVGAQQYQSWVPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKFKRFLRHPLPKTLEQLIQRGMEVQDGLEQAAEPSVTPLPTEDETEALTPALTSESVASDRTQPE", "length": 396 }, "evidence": [ { "id": "G5E5R8", "url": "https://omabrowser.org/oma/group/G5E5R8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7LC44-1", "protein_name": "Activity-regulated cytoskeleton-associated protein", "gene_name": "ARC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELDHRTSGGLHAYPGPRGGQVAKPNVILQIGKCRAEMLEHVRRTHRHLLAEVSKQVERELKGLHRSVGKLESNLDGYVPTSDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESTGGKYPVGSESARHTVSVGVGGPESYCHEADGYDYTVSPYAITPPPAAGELPGQEPAEAQQYQPWVPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELDLPQKQGEPLDQFLWRKRDLYQTLYVDADEEEIIQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEVQDDLEQAAEPAGPHLPVEDEAETLTPAPNSESVASDRTQPE", "length": 396 }, "evidence": [ { "id": "G5E5R8", "url": "https://omabrowser.org/oma/group/G5E5R8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8AWC3-1", "protein_name": "Activity-regulated cytoskeleton-associated protein", "gene_name": "ARC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQLDNVTNAGIHSFQGHRGVANKPNVILQIGKCRAEMLEHVRRTHRHLLSEVSKQVERELKGLQKSVGKLENNLEDHVPTDNQRWKKSIKACLARCQETIAHLERWVKREMNVWKEVFFRLEKWADRLESMGGKYCPGEHGKQTVSVGVGGPEIRPSEGEIYDYALDMSQMYALTPAPGEVPSIPQAHDSYQWVSVSEDAPASPVETQIFEDPHEFLSHLEEYLKQVGGTEEYWLSQIQNHMNGPAKKWWEYKQDSVKNWVEFKKEFLQYSEGTLTRDAIKRELDLPQKEGEPLDQFLWRKRDLYQTLYVDADEEEIIQYVVGTLQPKLKRFLSYPLPKTLEQLIQRGKEVQGNMDHSEEPSPQRTPEIQSGDSVESMPPSTTASPVPSNGTQPEPPSPPATVI", "length": 404 }, "evidence": [ { "id": "G5E5R8", "url": "https://omabrowser.org/oma/group/G5E5R8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9WV31-1", "protein_name": "Activity-regulated cytoskeleton-associated protein", "gene_name": "Arc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELDHMTTGGLHAYPAPRGGPAAKPNVILQIGKCRAEMLEHVRRTHRHLLTEVSKQVERELKGLHRSVGKLENNLDGYVPTGDSQRWKKSIKACLCRCQETIANLERWVKREMHVWREVFYRLERWADRLESMGGKYPVGSEPARHTVSVGVGGPEPYCQEADGYDYTVSPYAITPPPAAGELPEQESVEAQQYQSWGPGEDGQPSPGVDTQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRELELPQKQGEPLDQFLWRKRDLYQTLYVDAEEEEIIQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEVQDGLEQAAEPSGTPLPTEDETEALTPALTSESVASDRTQPE", "length": 396 }, "evidence": [ { "id": "G5E5R8", "url": "https://omabrowser.org/oma/group/G5E5R8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "neuronal ribonucleoprotein granule", "id": "GO:0071598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071598", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "virus-like capsid", "id": "GO:0170047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170047", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of long-term synaptic depression", "id": "GO:1900452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900452", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "regulation of long-term synaptic potentiation", "id": "GO:1900271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900271", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "regulation of neuronal synaptic plasticity", "id": "GO:0048168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048168", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "G5E5R8", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5R8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 396, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5R8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5R8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5R8" }, { "id": "PF18162", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Activity-regulated 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"Protein" ] }, { "id": "A0AAA9SUK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E657", "url": "https://www.uniprot.org/uniprotkb/G5E657", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E657-1", "url": "https://www.uniprot.org/uniprotkb/G5E657-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIGPVPWLGPLLLVSLWASSAPASLLRRLGEHILRFQESSALGLGLGPDSVTLPKEGWLEQPLDPFNASDRRSFLQRYWVNDQHWTSQDGPVFLHLGGEGSLGPGSVMRGHPANLAPIWGALVISLEHRFYGLSIPAEGLDMAQLRFLSSRHALADAASARLTLSRLFNVSSTSPWICFGGSYAGSLAAWARLKFPHLFFASIASSAPVRAILDFSKYNDVVSRSLMNTAIGGSLECRAAASAAFAEVERRLRASRGAWATLSVELGACGSLERAEDQAELLGALQALVGGAVQYDGQAGAPLSVRQLCRLLLGDRGNCKGNCSGSAPYRGLRRAVQVVTHSLGQRCLSIPRAETVAQLRVTELQVSSVGDRQWLYQTCTEFGYYVTCEVPGCPFSQLPALPSELELCEQVFGLSTSSVAQAVAQTNSYYGGQTPGATQVLFINGDTDPWHVLSVTQPLGSSEPALLIPSASHCLDMAPERPSDSPSLRLARQKVSQQLQTWLGLAKKSQVRGAV", "length": 516, "header": "tr|G5E657-1|G5E657_BOVIN Isoform 1 of Thymus-specific serine protease OS=Bos taurus OX=9913 GN=PRSS16 PE=3 SV=1 CANONICAL=G5E657-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SUK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUK3/entry", "sequence": { "sequence": "MDIGPVPWLGPLLLVSLWASSAPASLLRRLGEHILRFQESSALGLGLGPDSVTLPKEGWLEQPLDPFNASDRRSFLQVVTHSLGQRCLSIPRAETVAQLRVTELQVSSVGDRQWLYQTCTEFGYYVTCEVPGCPFSQLPALPSELELCEQVFGLSTSSVAQAVAQTNSYYGGQTPGATQVLFINGDTDPWHVLSVTQPLGSSEPALLIPSASHCLDMAPERPSDSPSLRLARQKVSQQLQTWLGLAKKSQVRGAV", "length": 255, "header": "tr|A0AAA9SUK3-1|G5E657_BOVIN Computationally mapped isoform of Thymus-specific serine protease OS=Bos taurus OX=9913 GN=PRSS16 PE=3 SV=1 CANONICAL=G5E657-1" }, "locus": { "chromosome": "23", "start_pos": 31315523, "end_pos": 31309241, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121851.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121851.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089028.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089028.1" } ] } }, { "isoform_ac": "G5E657-1", "url": "https://www.uniprot.org/uniprotkb/G5E657/entry", "sequence": { "sequence": "MDIGPVPWLGPLLLVSLWASSAPASLLRRLGEHILRFQESSALGLGLGPDSVTLPKEGWLEQPLDPFNASDRRSFLQRYWVNDQHWTSQDGPVFLHLGGEGSLGPGSVMRGHPANLAPIWGALVISLEHRFYGLSIPAEGLDMAQLRFLSSRHALADAASARLTLSRLFNVSSTSPWICFGGSYAGSLAAWARLKFPHLFFASIASSAPVRAILDFSKYNDVVSRSLMNTAIGGSLECRAAASAAFAEVERRLRASRGAWATLSVELGACGSLERAEDQAELLGALQALVGGAVQYDGQAGAPLSVRQLCRLLLGDRGNCKGNCSGSAPYRGLRRAVQVVTHSLGQRCLSIPRAETVAQLRVTELQVSSVGDRQWLYQTCTEFGYYVTCEVPGCPFSQLPALPSELELCEQVFGLSTSSVAQAVAQTNSYYGGQTPGATQVLFINGDTDPWHVLSVTQPLGSSEPALLIPSASHCLDMAPERPSDSPSLRLARQKVSQQLQTWLGLAKKSQVRGAV", "length": 516, "header": "tr|G5E657-1|G5E657_BOVIN Isoform 1 of Thymus-specific serine protease OS=Bos taurus OX=9913 GN=PRSS16 PE=3 SV=1 CANONICAL=G5E657-1" }, "locus": { "chromosome": "23", "start_pos": 31315523, "end_pos": 31309241, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054181.4", "url": "https://www.ensembl.org/id/ENSBTAT00000054181.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047551.2", "url": "https://www.ensembl.org/id/ENSBTAP00000047551.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614489", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZRF9-1", "protein_name": "Thymus-specific serine protease", "gene_name": "PRSS16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAARPVPWLGSLFLVSLWGASAPASLLRRLSEHIQLFQESAGLGPSLSLGSGAVAPPKEGWLEQPLDPFNASDRQSFLQRYWVNDQYWTSQDGPVFLHLGGEGSLGPGSVMRGHPAALAPVWGALVIGLEHRFYGLSIPAEGLDMAKLRFLSSRHALADVVSARLALTRLFNVSSSSPWICFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSKSLMNTAIGGSPECRAAVSSAFAEVERRLRAGGAALAALQAELGACGSLRRAADREELLGTLQALVGGAVQYDGQVGAPLSVRQLCGLFLGDRDNSSSPAPYLGLHRAVQVVTHSLGQKCLSFSRAETVAQLRVTEPQVSGLGERQWLYQTCTEFGYFVTCEDPGCPFSQLPALPSHLELCEQVFGLSTSSIAQAVARTNSYYGGQTPGATQVLFVNGDMDPWHVLSVTQALGPSESAILIPGASHCLDMAPEKPSDSPSLRLARQNIFLQLQTWLQLAKESQVKGEV", "length": 514 }, "evidence": [ { "id": "G5E657", "url": "https://omabrowser.org/oma/group/G5E657/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54GI7-1", "protein_name": "Peptidase S28 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIKIIVIFTIIVNVINGLAYPKYNAEELILDGSGSFPAQWFTQTLDHFNFQNNQTFQQKYYVNDQYYNYKNGGPIILYINGEGPVSSPPYSSDDGVVIYAQALNCMIVTLEHRFYGESSPFSELTIENLQYLSHQQALEDLATFVVDFQSKLVGAGHIVTIGGSYSGALSAWFRIKYPHITVGSIASSGVVHSILDFTAFDAYVSYAVGPECTKALQAVTSAAEDEYFAGGIREQQMKQILQAESLVDIGDFFYWLADSMMEGDQYGYIDELCSPLVDAINSGTSGIDLITVYSNYTINTWGKVLGTPDEYSTAWQQNVTYDPSKSADRAWWYQTCSSLGWMQAAPSENSIRSSLVNMTYFQTHCQQLFGQAIWPPNVNAVNTQYGGDQSNPLLNAAGTNILFTNGHADPWSQASIVNSNYPNVEPSAMTTCRKCGHCVDLRGCPGGCDLPNNLDQVRSLSLKSIAQWLNLNN", "length": 476 }, "evidence": [ { "id": "G5E657", "url": "https://omabrowser.org/oma/group/G5E657/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NQE7-1", "protein_name": "Thymus-specific serine protease", "gene_name": "PRSS16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVWLAQWLGPLLLVSLWGLLAPASLLRRLGEHIQQFQESSAQGLGLSLGPGAAALPKVGWLEQLLDPFNVSDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGALVISLEHRFYGLSIPAGGLEMAQLRFLSSRLALADVVSARLALSRLFNISSSSPWICFGGSYAGSLAAWARLKFPHLIFASVASSAPVRAVLDFSEYNDVVSRSLMSTAIGGSLECRAAVSVAFAEVERRLRSGGAAQAALRTELSACGPLGRAENQAELLGALQALVGGVVQYDGQTGAPLSVRQLCGLLLGGGGNRSHSTPYCGLRRAVQIVLHSLGQKCLSFSRAETVAQLRSTEPQLSGVGDRQWLYQTCTEFGFYVTCENPRCPFSQLPALPSQLDLCEQVFGLSALSVAQAVAQTNSYYGGQTPGANKVLFVNGDTDPWHVLSVTQALGSSESTLLIRTGSHCLDMAPERPSDSPSLRLGRQNIFQQLQTWLKLAKESQIKGEV", "length": 514 }, "evidence": [ { "id": "G5E657", "url": "https://omabrowser.org/oma/group/G5E657/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXE5-1", "protein_name": "Thymus-specific serine protease", "gene_name": "Prss16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVKAPWLGFLLLVSLWGLSTPALLLRRLREHIQKFQESSSLHPGFGLGHGPGAVPKQGWLEQPLDPFNASDRRTFLQRYWVNDQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEHRFYGLSMPAGGLDLALLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLATWARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQVAIGGSLECLAAASTAFTEVERLLRAGPAAQAVLREELGACGSLDLTEDQAELLGALQALVGGTVQYDGQAGAPLSVRQLCGLLLGKWGNRSRSTPYLGLRRAVQIVLRSMGQKCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQLELCEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKSQS", "length": 509 }, "evidence": [ { "id": "G5E657", "url": "https://omabrowser.org/oma/group/G5E657/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G5E657", "url": "https://www.uniprot.org/uniprotkb/G5E657" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type exopeptidase activity", "id": "GO:0070008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070008", "evidence": [ { "database": "UniProtKB", "id": "G5E657", "url": "https://www.uniprot.org/uniprotkb/G5E657" } ], "pmid": "" }, { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "G5E657", "url": "https://www.uniprot.org/uniprotkb/G5E657" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "G5E657", "url": "https://www.uniprot.org/uniprotkb/G5E657" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "G5E657", "url": "https://www.uniprot.org/uniprotkb/G5E657" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E657-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 516, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E657-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E657" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LFZ9-1", "uniprot_ac": "A0A3Q1LFZ9", "uniprot_id": "A0A3Q1LFZ9_BOVIN", "mass": { "chemical_mass": 70918.0, "monoisotopic_mass": 70918.0 }, "refseq": {}, "gene_names": [ { "name": "SLC28A1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ] } ], "protein_names": [ { "name": "Sodium/nucleoside cotransporter", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC28A1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9", "locus": { "chromosome": "21", "start_pos": 22586295, "end_pos": 22524624, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020250", "url": "https://www.ensembl.org/id/ENSBTAG00000020250" } ] } } ], "crossref": [ { "id": "A0A3Q1LFZ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LFZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020250", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020250", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IVWHTVI", "url": "https://omabrowser.org/oma/group/IVWHTVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFZ9", "url": "https://www.orthodb.org/?gene=A0A3Q1LFZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N108", "url": "https://www.orthodb.org/?gene=F1N108", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10590:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10590:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-83936", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-83936", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZT8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N108", "url": "https://www.uniprot.org/uniprotkb/F1N108", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N108-1", "url": "https://www.uniprot.org/uniprotkb/F1N108-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDNTPRGRESISLTSVAIGLDNRGADLLESLEEGRDPAGNSSPSEVGDSWSKAGPEPFSGWRRRLQPALRVRHFCREHAQLFRWICIGLLCTAYTAFLLAACILNFQRALALFVLTCVVLVFLAHSLLKRLLGPKLLRCVKPLGHPCLKLWFKRGLALAAFLGLVLWLALDTSQRPEQLVSFGGICVFVGFLFAVSKHHRAVSWRAVFWGLGLQFVLGLVVIRTEPGFIAFQWLGDQIQIFLSYTESGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVIMKISWLMQITMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLLEAASSGAALSVKVVTNIAANLIAFLAVLDFINAALSWLGNMVDIQGLSFQLICSYILRPVAFLMGVAWEDCSVVAELLGMKLFLNEFVAYQGLSEYKQRRLAGTEEWVGSKKQWISVRAEILTTFALCGFANFSSIGIMLGGLTSMAPQRKSDFSQIVLRALCTGACVSLVNACVAGILYMPRGPAVDCVSLLNTTLNSSSFEVYQCCHQAFQSTGPEFSLEALDNCCRFYNHTICA", "length": 649, "header": "tr|A0A3Q1LFZ9-1|A0A3Q1LFZ9_BOVIN Isoform 1 of Sodium/nucleoside cotransporter OS=Bos taurus OX=9913 GN=SLC28A1 PE=3 SV=2 CANONICAL=A0A3Q1LFZ9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9/entry", "sequence": { "sequence": "MEDNTPRGRESISLTSVAIGLDNRGADLLESLEEGRDPAGNSSPSEVGDSWSKAGPEPFSGWRRRLQPALRVRHFCREHAQLFRWICIGLLCTAYTAFLLAACILNFQRALALFVLTCVVLVFLAHSLLKRLLGPKLLRCVKPLGHPCLKLWFKRGLALAAFLGLVLWLALDTSQRPEQLVSFGGICVFVGFLFAVSKHHRAVSWRAVFWGLGLQFVLGLVVIRTEPGFIAFQWLGDQIQIFLSYTESGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVIMKISWLMQITMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLLEAASSGAALSVKVVTNIAANLIAFLAVLDFINAALSWLGNMVDIQGLSFQLICSYILRPVAFLMGVAWEDCSVVAELLGMKLFLNEFVAYQGLSEYKQRRLAGTEEWVGSKKQWISVRAEILTTFALCGFANFSSIGIMLGGLTSMAPQRKSDFSQIVLRALCTGACVSLVNACVAGILYMPRGPAVDCVSLLNTTLNSSSFEVYQCCHQAFQSTGPEFSLEALDNCCRFYNHTICA", "length": 649, "header": "tr|A0A3Q1LFZ9-1|A0A3Q1LFZ9_BOVIN Isoform 1 of Sodium/nucleoside cotransporter OS=Bos taurus OX=9913 GN=SLC28A1 PE=3 SV=2 CANONICAL=A0A3Q1LFZ9-1" }, "locus": { "chromosome": "21", "start_pos": 22585722, "end_pos": 22525806, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075356.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075356.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057227.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057227.2" } ] } }, { "isoform_ac": "A0AAA9SZT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZT8/entry", "sequence": { "sequence": "MSLAQSTGLSRRKAETLPATQALRKLGTAGARLARSPSRDAYTAFLLAACILNFQRALALFVLTCVVLVFLAHSLLKRLLGPKLLRCVKPLGHPCLKLWFKRGLALAAFLGLVLWLALDTSQRPEQLVSFGGICVFVGFLFAVSKHHRAVSWRAVFWGLGLQFVLGLVVIRTEPGFIAFQWLGDQIQIFLSYTESGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVIMKISWLMQITMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLLEAASSGAALSVKVVTNIAANLIAFLAVLDFINAALSWLGNMVDIQGLSFQLICSYILRPVAFLMGVAWEDCSVVAELLGMKLFLNEFVAYQGLSEYKQRRLAGTEEWVGSKKQWISVRAEILTTFALCGFANFSSIGIMLGGLTSMAPQRKSDFSQIVLRALCTGACVSLVNACVAGILYMPRGPAVDCVSLLNTTLNSSSFEVYQCCHQAFQSTGPEFSLEALDNCCRFYNHTICA", "length": 596, "header": "tr|A0AAA9SZT8-1|A0A3Q1LFZ9_BOVIN Computationally mapped isoform of Sodium/nucleoside cotransporter OS=Bos taurus OX=9913 GN=SLC28A1 PE=3 SV=1 CANONICAL=A0A3Q1LFZ9-1" }, "locus": { "chromosome": "21", "start_pos": 22585722, "end_pos": 22527067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107525.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107525.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091992.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091992.1" } ] } }, { "isoform_ac": "F1N108-1", "url": "https://www.uniprot.org/uniprotkb/F1N108/entry", "sequence": { "sequence": "MGPTCPISSSLREGRVPAPAVAQDSGVGAGPSQVGGPASFNSGLCPGISSEMRRPAKAQAGWIQPIPVETRTSVCPPERLVDHKYEEGRDPAGNSSPSEVGDSWSKAGPEPFSGWRRRLQPALRVRHFCREHAQLFRWICIGLLCTAYTAFLLAACILNFQRALALFVLTCVVLVFLAHSLLKRLLGPKLLRCVKPLGHPCLKLWFKRGLALAAFLGLVLWLALDTSQRPEQLVSFGGICVFVGFLFAVSKHHRAVSWRAVFWGLGLQFVLGLVVIRTEPGFIAFQWLGDQIQIFLSYTESGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVIMKISWLMQITMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLLEAASSGAALSVKVVTNIAANLIAFLAVLDFINAALSWLGNMVDIQGLSFQLICSYILRPVAFLMGVAWEDCSVVAELLGMKLFLNEFVAYQGLSEYKQRRLAGTEEWVGSKKQWISVRAEILTTFALCGFANFSSIGIMLGGLTSMAPQRKSDFSQIVLRALCTGACVSLVNACVAGILYMPRGPAVDCVSLLNTTLNSSSFEVYQCCHQAFQSTGPEFSLEALDNCCRFYNHTICA", "length": 702, "header": "tr|F1N108-1|A0A3Q1LFZ9_BOVIN Computationally mapped isoform of Sodium/nucleoside cotransporter OS=Bos taurus OX=9913 GN=SLC28A1 PE=3 SV=2 CANONICAL=A0A3Q1LFZ9-1" }, "locus": { "chromosome": "21", "start_pos": 22585722, "end_pos": 22524697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026974.5", "url": "https://www.ensembl.org/id/ENSBTAT00000026974.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026974.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026974.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-83936", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-83936", "resource": "Reactome", "description": "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZNF3-1", "protein_name": "Sodium/nucleoside cotransporter", "gene_name": "SLC28A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDNTPRQRDPISLTSVANGLENMGAELLESLEEGRTPGSDSSPAEVGGSWSKAGPEHLGRRSLQPALRVRRFCREHTQLFRWICTGLLCTAFAAFLLIACLLDFQRALALFVLFCVVLFFLAHSLLKRLLGPKLLRCVKPLRHPCLNLWFKRGLALAAFLGLVLWLVLDTAQRPEQLVSFGGICVFILLLFAGSKHHRAVSWRAVSWGLGLQFALGLFVIRTEPGFIAFQWLGDQIQIFLSYTEAGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVILKISWLMQATMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFKREEGVKLTYGDAQNLLEAASSGAAMSVRVVTNIAANLIAFLAVLAFINAALSWLGDMVDVQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGMKLFLNEFVAYQELSGYKQRRLAGAEEWVGSRKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSMVPQRKGDFSQIVLRALCTGACVSLVNACVAGILYVPRGAEVDCVSFLNTTLSSSSFEVYQCCRQFFQSTSLEFSPEALDNCCRFYNHTICVQ", "length": 648 }, "evidence": [ { "id": "A0A3Q1LFZ9", "url": "https://omabrowser.org/oma/group/A0A3Q1LFZ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZMH5-1", "protein_name": "Sodium/nucleoside cotransporter", "gene_name": "SLC28A2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARLEMEGNQITLDSLEKGIDNPAFSSLGEEELCEERGGPRGGNEKRREGNGRVALYCRKALRPASKAKRFCKAHAKALRRVFWGLLGAAYLCYFIAACWLNFQRALALVVITAVVIFFVCWSLFKKYCGAKVLTLLSPLWKCLQKSWPWLKWLLYVLLLGGLVTWLALDTAKNPEQLISLAGFCVLVLFLFAFSKHHSAVSWRAVFWGLGLEFLIGLFILRTTPGIQAFQWLGDQIQVFLGYTKAGSGFVFGNTLIEDVFAFQSLPIIVFFSCVMSILYYLGVMQWLILKISWLLQVSLGTTPTETLSVAGNIFVGQTEAPLLIRPYLADMTHSEIHAVMAGGFSTIAGSVMGAYISFGIDAASLIAASVMAAPCALAMSKLVYPEVEESKFKGKESVRIASGEERNILEAASNGAAASVGLVANIAANLIAFLAVLEFINAALRWFGEMVEIENLSFEMICSYVLMPVAFLMGADWADSPLVAELLGIKIFLNEFVAYQQLATYKKNRLSGLEEWSEGRKQWISERAESITTFALCGFANLSSIGIMLGGLTSMVPQRKSELASIVLRALLTGICVSMLNSCLAGLLYVPTEMGNCVTILSTANFTSTNYAIYTCCKQLFASTVLENGTLSFTGAWASVAESVPCLTQCCGYYNHTSCTV", "length": 662 }, "evidence": [ { "id": "A0A3Q1LFZ9", "url": "https://omabrowser.org/oma/group/A0A3Q1LFZ9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PXX9-1", "protein_name": "Sodium/nucleoside cotransporter 1", "gene_name": "Slc28a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADDTPRQRESISLTPVAHGLENMGAEFLEIMEEGQLPHRHSSLPEGGGSRSKAVWKPFSRWRSLQPTVQARSLCREHWQLFEWISKGLLSTAYIGFLIVACLLDFPRALALFVITCVVLVFLAYNLLKRLLGSKLKKCVKFQGHSCLSLWLKRGLALAAGLGVILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFVAFQWLGDQIRVFLSYTEAGSSFVFGEALVKDVFAFQVLPIIVFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDASSLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLVEAASAGAAISVKVVANIAANLIAFLAVLAFINAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSMVPQRRSDFSQIVLRALITGAFVSLVNACVAGILYVPRGVEVDCMSLLNQTVSSSSFEVYLCCRQVFQNTSLEFGQEALHNCCRFYNHTVCT", "length": 648 }, "evidence": [ { "id": "A0A3Q1LFZ9", "url": "https://omabrowser.org/oma/group/A0A3Q1LFZ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O00337-1", "protein_name": "Sodium/nucleoside cotransporter 1", "gene_name": "SLC28A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENDPSRRRESISLTPVAKGLENMGADFLESLEEGQLPRSDLSPAEIRSSWSEAAPKPFSRWRNLQPALRARSFCREHMQLFRWIGTGLLCTGLSAFLLVACLLDFQRALALFVLTCVVLTFLGHRLLKRLLGPKLRRFLKPQGHPRLLLWFKRGLALAAFLGLVLWLSLDTSQRPEQLVSFAGICVFVALLFACSKHHCAVSWRAVSWGLGLQFVLGLLVIRTEPGFIAFEWLGEQIRIFLSYTKAGSSFVFGEALVKDVFAFQVLPIIVFFSCVISVLYHVGLMQWVILKIAWLMQVTMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDATSLIAASVMAAPCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAISVKVVANIAANLIAFLAVLDFINAALSWLGDMVDIQGLSFQLICSYILRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQDLSKYKQRRLAGAEEWVGDRKQWISVRAEVLTTFALCGFANFSSIGIMLGGLTSMVPQRKSDFSQIVLRALFTGACVSLVNACMAGILYMPRGAEVDCMSLLNTTLSSSSFEIYQCCREAFQSVNPEFSPEALDNCCRFYNHTICAQ", "length": 649 }, "evidence": [ { "id": "A0A3Q1LFZ9", "url": "https://omabrowser.org/oma/group/A0A3Q1LFZ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62674-1", "protein_name": "Sodium/nucleoside cotransporter 1", "gene_name": "Slc28a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADNTQRQRESISLTPMAHGLENMGAEFLESMEEGRLPHSHSSLPEGEGGLNKAERKAFSRWRSLQPTVQARSFCREHRQLFGWICKGLLSTACLGFLMVACLLDLQRALALLIITCVVLVFLAYDLLKRLLGSKLRRCVKFQGHSCLSLWLKRGLALAAGVGLILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFIAFQWLGDQIQVFLSYTEAGSSFVFGEALVKDVFAFQVLPIIIFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSENGVKLTYGDAQNLLEAASAGAAISVKVVANIAANLIAFLAVLAFVNAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKFFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSLVPQRRSDFSQIVLRALITGAFVSLLNACVAGILYVPRGVEVDCVSLLNQTVSSSSFEVYLCCRQVFQSTSSEFSQVALDNCCRFYNHTVCT", "length": 648 }, "evidence": [ { "id": "A0A3Q1LFZ9", "url": "https://omabrowser.org/oma/group/A0A3Q1LFZ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "nucleoside transmembrane transporter activity", "id": "GO:0005337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005337", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "uridine transmembrane transporter activity", "id": "GO:0015213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015213", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "pyrimidine- and adenosine-specific:sodium symporter activity", "id": "GO:0015389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015389", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "azole transmembrane transporter activity", "id": "GO:1901474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901474", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cytidine transport", "id": "GO:0015861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015861", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "uridine transmembrane transport", "id": "GO:0015862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015862", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "pyrimidine nucleobase transport", "id": "GO:0015855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015855", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" }, { "name": "nucleoside import across plasma membrane", "id": "GO:0180015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180015", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LFZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" }, { "id": "PF07662", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07662" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Concentrative nucleoside transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 368, "end_pos": 589, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LFZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" }, { "id": "PF01773", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01773" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Concentrative nucleoside transporter N-terminal", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 256, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LFZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFZ9" }, { "id": "PF07670", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07670" } ], "ann_type": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AWNKSTE", "url": "https://omabrowser.org/oma/group/AWNKSTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TKG8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKG8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5A0-1", "url": "https://www.uniprot.org/uniprotkb/G5E5A0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPLEKPGSGGSSPAVASGSGRAGRGLSTPRRPPPPTQARGLLTEIRTAVRTEHFQDAYTLTPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIVHEIAVLELAQDNPWVINLHEVYETPSEMILVLEYAAGGEIFDQCVADRDEAFTEKDVQRLMRQILEGVCFLHAHDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRIMKKSEELREIMGTPEYVAPEVLSYDPISTATDMWSIGVLAYVMLTGISPFLGDDKQETFLNISQMNLSYSEEEFDVVSESAVDFIKTLLVKKPDVNCVSLSRDRATAEECLKHPWLTQSGVQEPAFKVKGALEEAHALQEADPVSESNSDTQKPETEESIVTEELILVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQDIPGDFIY", "length": 422, "header": "tr|G5E5A0-1|G5E5A0_BOVIN Isoform 1 of Serine/threonine-protein kinase 17A OS=Bos taurus OX=9913 GN=STK17A PE=3 SV=3 CANONICAL=G5E5A0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TKG8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKG8/entry", "sequence": { "sequence": "MDGGAWWAAVHWVTKSRTRLSYFTLYVLEGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIVHEIAVLELAQDNPWVINLHEVYETPSEMILVLEYAAGGEIFDQCVADRDEAFTEKDVQRLMRQILEGVCFLHAHDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRIMKKSEELREIMGTPEYVAPEVLSYDPISTATDMWSIGVLAYVMLTGISPFLGDDKQETFLNISQMNLSYSEEEFDVVSESAVDFIKTLLVKKPEDRATAEECLKHPWLTQSGVQEPAFKVKGALEEAHALQEADPVSESNSDTQKPETEESIVTEELILVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQDIPGDFIY", "length": 374, "header": "tr|A0AAA9TKG8-1|G5E5A0_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase 17A OS=Bos taurus OX=9913 GN=STK17A PE=3 SV=1 CANONICAL=G5E5A0-1" }, "locus": { "chromosome": "4", "start_pos": 77512349, "end_pos": 77479194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093446.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093446.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097438.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097438.1" } ] } }, { "isoform_ac": "G5E5A0-1", "url": "https://www.uniprot.org/uniprotkb/G5E5A0/entry", "sequence": { "sequence": "MIPLEKPGSGGSSPAVASGSGRAGRGLSTPRRPPPPTQARGLLTEIRTAVRTEHFQDAYTLTPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIVHEIAVLELAQDNPWVINLHEVYETPSEMILVLEYAAGGEIFDQCVADRDEAFTEKDVQRLMRQILEGVCFLHAHDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRIMKKSEELREIMGTPEYVAPEVLSYDPISTATDMWSIGVLAYVMLTGISPFLGDDKQETFLNISQMNLSYSEEEFDVVSESAVDFIKTLLVKKPDVNCVSLSRDRATAEECLKHPWLTQSGVQEPAFKVKGALEEAHALQEADPVSESNSDTQKPETEESIVTEELILVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQDIPGDFIY", "length": 422, "header": "tr|G5E5A0-1|G5E5A0_BOVIN Isoform 1 of Serine/threonine-protein kinase 17A OS=Bos taurus OX=9913 GN=STK17A PE=3 SV=3 CANONICAL=G5E5A0-1" }, "locus": { "chromosome": "4", "start_pos": 77515073, "end_pos": 77479194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010704.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010704.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010704.6", "url": "https://www.ensembl.org/id/ENSBTAP00000010704.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PV76-1", "protein_name": "Serine/threonine-protein kinase 17A", "gene_name": "STK17A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSPEEKPPPGRSHDECSPQPAAGRGRRRGGLLTEIRTPIRTEPFQQRYSLSPGRELGRGKFAVVKKCIQKDTEREFAAKFMRKRRKGQDCRMEIIHEIAVLELAQCNLWVINLHEVYETATEMILVLEYAAGGEIFDQCVAEREEAFKEKDVKRLMKQILEGVSFLHRNNVVHLDLKPQNILLTSKSPLGDIKIVDFGLSRIVKSSEELREIMGTPEYVAPEILSYDPISTATDMWSIGVLAYIMLTGISPFLGDDKQETFLNISQMNVCYTGEDFDLISESAVDFMKTLLVKKPEERATAEECLQHPWLEQSDEPTCRAWSKSARRENSDVIQKNADSASEKPVDVEKAEEEESVITEELIVVASYTLGQCRQSEKEKATEQKAISKRFKFEEPLLQEIPGEFIY", "length": 406 }, "evidence": [ { "id": "G5E5A0", "url": "https://omabrowser.org/oma/group/G5E5A0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SSF3-1", "protein_name": "Serine/threonine-protein kinase 17A", "gene_name": "STK17A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIPLEKPGSGDSSPAAASGSGRASRGPSTPRRPPPPARGLLTEIRTAVRTEPFQDSYSLSPGRELGRGKFAVVRKCIKKDSGREFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETPSEMILVLEYAAGGEIFDQCVADREEAFTEKDVQRLMRQILEGVRFLHAHDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRIMKKSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGVSPFLGDSKQETFLNISRMNLNYSEEEFDVVSESAVDFIKALLVKEPEDRATAEECLKHPWLAQGSAQEPSCKLKGAPEEAQALQEGDSVPESNSDPQTPETQEPVLTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGDFIY", "length": 412 }, "evidence": [ { "id": "G5E5A0", "url": "https://omabrowser.org/oma/group/G5E5A0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9UEE5-1", "protein_name": "Serine/threonine-protein kinase 17A", "gene_name": "STK17A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY", "length": 414 }, "evidence": [ { "id": "G5E5A0", "url": "https://omabrowser.org/oma/group/G5E5A0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" }, { "name": "regulation of reactive oxygen species metabolic process", "id": "GO:2000377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000377", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" }, { "name": "positive regulation of fibroblast apoptotic process", "id": "GO:2000271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000271", "evidence": [ { "database": "UniProtKB", "id": "G5E5A0", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": 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{ "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] } ] }, { "uniprot_ac": "A0A3Q1M1Z0", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] } ] }, { "uniprot_ac": "A0A3Q1M2U5", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { 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}, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { 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"https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22796:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059731100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731100", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TMQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6A5", "url": "https://www.uniprot.org/uniprotkb/G5E6A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6A5-1", "url": "https://www.uniprot.org/uniprotkb/G5E6A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDTERQLNIKGELSHRKSLTDRELVRHASGGLALEGIYKTSDQRSLIKKKEELLCVPKDFVLRGPEQGTRMEMKEFTSSQEESKFTQIVEKLGFSVSALAKCGGWGISLKAGMDQSMHSESKKTQQSHSTHSYFCSIKFIYIPLASFYFPVDQLQLSNAALEELKYIENLLSQSEDSDELCLLRHRTEAFFQRYGSHANQGPLHLGGIYWWKAISEGFQKEQLAEVKQQAAEALNIYIKGGYSGFGVNIGTGLDMSDSHLKKASQKTTFQNLQTEVQLSVAQTGGPPEANGFFDWKAGLVANNQTWCVIDRGLQLVPVWDIVLSSHRSDFKDPHKLANCLKAHYTVLNELTAQIQERELLSIEKEARIFLEDVKSWKVFDPEEQLKRLINFMQRLSQKTGSYTTWTNICLKDRGLQNFLVNMVNFCKKSSIYGTTFIKFQLSHLLDPHIYIVTNFPQAHSIMEWIFQSEPKEDNVPITQFSELIEIFKKAQKGLREVKANSESTELVEEAQRKLTYEVSLSLGCFLKYLRETGKPDTHILLLLIASGAGYHVVDNIFQYLLGHDELDFLLEKTQTAPNKYQELKNICNYRAQAFLVLTGLTATAGIKAVSQEEKTQRLALIKHHMGQSLTKEVVHVLTNHGDHDWQNLDKDLRLLIDGKYEDAVSSLQVEEVIKELQSVFHEKKEPHEPHDNEKKKKEVIENGAFQDLLQRLGLEHYYPRKMSRANFQLIHKTSVYNTQPCSERELPFYFLQKLLMLDYGLRYLIIKHEDYTENQVYSSTSNQEKEAFDPYEDLPEESAHPTKPSAATNARLYVHPMDVQMAILHCADDFGRQYILDKLSICQFALPLLIPNPCNAQIEFSLWSLRQIRRSWQQVGKSIKEEKDNYTNQQMCRVSAPIVSFIRVGTGFSASKSQIMNCLLSERKHDVFFHRHCNGSSRDCLLMGGVVEVAWFCPGGEEQDRFDNCLTFTNLHGDAKEYEKQLAFLKEVSSIIVVLMSTSDDNKGNRKIVRDMCQSSKPLIFLLDDKGKITVNDSGSRVRIGIRNRNEAELIGELTTTIRRLLELCNTALSLENCAQVARKQGMLIDEDQRDCKEAKEKAEAIITLLREMEISQVKENLLPLQGKLWQLWCKKDKELYHLREKGNRSIEQHKSETETEKQMIRLEQLRKAFPLNALMCSVLEILQNHSETHTKLYFLQWLNVALDNLTARHLENLNEKKKALVQKEKQEAPKSSSLKDWQNEIEAISREINDCTLGIEHILREAGQIYEALEEASPMKDTLFLSLPHIAADLMISGVPIELMDGDVSYVPLKWVAAVFDKLSEKLGNKRLFVLSVLGLQSSGKSTLLNALFGLQFTLSAGRCTRGAYMQLLKVEETFTAELGFDFVLVVDTEGLRAPELSNKSQNHDNELATFVIGLGNLTLINIMGGNPSEMQDIRQIVIQAFLRMKQVKISPSCLFVHQNVREVTAKDQTMEGRRQLEERLDELAAIAAAEEQCSNVTCFSDVIKFDVNTHIYYFAHLWDGNPPMAPPNPRYSHNVQELKSRILVTAQQESRGSIMKISDVKSRVQDLWRALRNENFIFSFRNTQEVMVMSKLETMYNSWTWELRSDVQRLQDELISQIQNGKIQTLETYTLEAPVTEIYEAIKQKLEKYFNEDPDSEVLVQWKGNFENKLITLKQALILDGQRKAKELISFKKNQEKPGNKKSGYEKELLEKSRKLALSLSGTELSEEELHEEFNPLWEKWVYDVSSSLPLAVEPEIEVDYENILLDYFKKEKDIVSILKNYSGEKFEINYDKHVKMNRNFWGLTTMTIETQDIHSINMTTDCIISKVNETVNKISQQKHDYNPTYFHEILRIIHEEMKSAPTQKRYTFTRKYEIDLSLCLFQRASVKFKEMHKAFKRANDPVHYLQSKKDDFFMSFKISCQGATSIKTFVDFLWKKLTPAVSSTIRKNTALKIAGDIRTTCRAFNENRANLEKHILISLAEEENFDNYCQYLHNPESFFKNYIENHVKRYLSDTGSKKIKTFLQMSLHDIKNATLSAIHASTAIAKDKSSTVSGWLDLFCDHLGSTLTFPRKDLISIEHQEIKDIEFIKEAMSKALDPEMKKVEQNCLSKLVEEMIPEIQKMLFEHLCGCWKQCPFCKAICTNTIPTHEGDHSVPFHRPKALSGWGWYQTDHFVIEHCTSLVASDCDFVLNDGRRIPYKTYRQAGGEYATWSITPDTSTQPYWKWFVCHFRSKLEEKYHKRLFNEGEIPDAWNKITKQDVLDDLKKN", "length": 2271, "header": "tr|G5E6A5-1|G5E6A5_BOVIN Isoform 1 of VLIG-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC101903126 PE=3 SV=2 CANONICAL=G5E6A5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TMQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMQ4/entry", "sequence": { "sequence": "MEDTERQLNIKGELSHRKSLTDRELVRHASGGLALEGIYKTSDQRSLIKKKEELLCVPKDFVLRGPEQGTRMEMKEFTSSQEESKFTQIVEKLGFSVSALAKCGGWGISLKAGMDQSMHSESKKTQQSHSTHSYFCSIKFIYIPLASFYFPVDQLQLSNAALEELKYIENLLSQSEDSDELCLLRHRTEAFFQRYGSHANQGPLHLGGIYWWKAISEGFQKEQLAEVKQQAAEALNIYIKGGYSGFGVNIGTGLDMSDSHLKKASQKTTFQNLQTEVQLSVAQTGGPPEANGFFDWKAGLVANNQTWCVIDRGLQLVPVWDIVLSSHRSDFKDPHKLANCLKAHYTVLNELTAQIQERELLSIEKEARIFLEDVKSWKVFDPEEQLKRLINFMQRLSQKTGSYTTWTNICLKDRGLQNFLVNMVNFCKKSSIYGTTFIKFQLSHLLDPHIYIVTNFPQAHSIMEWIFQSEPKEDNVPITQFSELIEIFKKAQKGLREVKANSESTELVEEAQRKLTYEVSLSLGSFLKNLQEMGKPDTRILLLLIASGAGYHVGDNKFQYPLGHDELDFLLDKMQTAQNKYQELKNICNYRAQAFLVLTGLTATVRIKAISPEEKTQHLALIKQYMGRSLTKEVVYVLTNHGDHDWENLEKDLRLLIDGKYEAAVSSLQVEEMIKELQSVFHEKKEPHEPHDNEKKKEEVIENGAFQDLLQRLGLEHYYPRKMSRANFQLIHKTVYNTQPCSERELHFYFLQKLLVLDYGLRYLIIKHEEYTENQVYSSTSNQEKEAFDPYEDLPEESAHPTEPSAATNVRPYVHPMDIQMAILHCADDFGRQYILDKLSTCQFALPLLIPNPCNAQIEFSLWSLSQIRRSWQQVGKSIKGEKDNYMNQQMCHVSAPIVSFIRVGTGFSASKSQIMNCLLSERKHDVFFHRHCKGSSRDCLLMGGVVEVAWFCPGGEEQDRFDNCLTFMNLHGDAKEYEKQLAFLQEVSSIIVVLMSTSEDNKGNQKLVHDMCQSSKPLIFLLDDKGKITVNDSGSRVRIGIRNRNEAELIGELTTTIKRLLELSNTALSLENCAQVAHKQGMLIDANQRHCKEAKEKAEAIITLLREMEMPQVKENLLPLQGKLWQLWCKKDKELYHLREKGNRSIEQHKSETETEKQMIRHAQFRKAFPLNALMRSVLEILQNHSETHTKLYFLQWLNVALDNLTAGHLENLNEKKKELIQKENQEAPKSSSLKDWQNDIEAISREINDCTLGIEHILREAGQIYEALEEASPMKDTLFFSLPHIAADLMISGVPIELLDGDVSYVPLRWVAAVFDKLSEKLGNKRLFVLSVLGLQSSGKSTLLNALFGLQFTVSAGRCTRGAYMQLLKVEETFTAELGFDFVLVVDTEGLRAPELSNKSQNHDNELATFVIGLANLTLINIMGENPSEMQDILQIVVQAFLRMKQVKISPTCLFVHQNVGEVTAKDQNMEGRRRLKQTLDKMAAIAAEEEQCSNVSCFSDVIKFDVNTHVYYFAHLWDGNPPMAPPNPRYSHNVQELKSRILVTAQQESRGSIMKISDVKFRVQDLWRALLNENFIFSFRNTQEVMAMSKLETMYNSWTWELRSHVQRLQDQLINQIQNGKIQTLKTYTLEAPVREIYEAIKQKLEKYFYEDPDSEVLVQWKGNFENKLITLKEELILDVQRKAKELISLKKNQEKLDNKKSSYEKELLEKSRNLALSLNGTELSEEELHEKFNSVWKKWVYDVSSSLPPATDPEIKVDSENILLEYFKKEKDIVSILKNSSGEKFEINYDNHVKMNRKSGELSTMTIENQDIHSINTTTDCLISKVNETVNKICQQKHDYNLTYFHEILRIIEEEVKSEPTQKRYTFTRKYEIDLSLYLFQRASVKFKEMHKAFKRANDPVHYLQCKKDDFFMSFKISCQGATSIKMFVDFLWKKLTPAVSSTIRKNMALKIAGDIRTTCRAFNENRANLEKHILISLAEEENFDNYCQYLHNPESFFKNYIENHVKRYLSDTGSEKIKTFLQMSLDDIKIAILSAIHASTAIAKDKSSTVSGWLDLFCDHLGSTLIFPRKDLVSIEHQEIKDIEFIKEAMSKALDSAMNSEEQNCLSRLVEEMIPEIQKMLFEHLCGCWKQCPFCKAICTNTIPTHEGDHSVPFHRPKALSGWGWYQTDHFVIEHCTSLVASDCDFVLNDGRTILYKTYRQAGGEYATWSITPDTSTQPYWKWFVCHFRSKLEEKHHKRFINKGEIPDAWNKITKQDVLDDLKKN", "length": 2270, "header": "tr|A0AAA9TMQ4-1|G5E6A5_BOVIN Computationally mapped isoform of VLIG-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC101903126 PE=3 SV=1 CANONICAL=G5E6A5-1" }, "locus": { "chromosome": "15", "start_pos": 46362503, "end_pos": 46229081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128101.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128101.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099783.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099783.1" } ] } }, { "isoform_ac": "G5E6A5-1", "url": "https://www.uniprot.org/uniprotkb/G5E6A5/entry", "sequence": { "sequence": "MEDTERQLNIKGELSHRKSLTDRELVRHASGGLALEGIYKTSDQRSLIKKKEELLCVPKDFVLRGPEQGTRMEMKEFTSSQEESKFTQIVEKLGFSVSALAKCGGWGISLKAGMDQSMHSESKKTQQSHSTHSYFCSIKFIYIPLASFYFPVDQLQLSNAALEELKYIENLLSQSEDSDELCLLRHRTEAFFQRYGSHANQGPLHLGGIYWWKAISEGFQKEQLAEVKQQAAEALNIYIKGGYSGFGVNIGTGLDMSDSHLKKASQKTTFQNLQTEVQLSVAQTGGPPEANGFFDWKAGLVANNQTWCVIDRGLQLVPVWDIVLSSHRSDFKDPHKLANCLKAHYTVLNELTAQIQERELLSIEKEARIFLEDVKSWKVFDPEEQLKRLINFMQRLSQKTGSYTTWTNICLKDRGLQNFLVNMVNFCKKSSIYGTTFIKFQLSHLLDPHIYIVTNFPQAHSIMEWIFQSEPKEDNVPITQFSELIEIFKKAQKGLREVKANSESTELVEEAQRKLTYEVSLSLGCFLKYLRETGKPDTHILLLLIASGAGYHVVDNIFQYLLGHDELDFLLEKTQTAPNKYQELKNICNYRAQAFLVLTGLTATAGIKAVSQEEKTQRLALIKHHMGQSLTKEVVHVLTNHGDHDWQNLDKDLRLLIDGKYEDAVSSLQVEEVIKELQSVFHEKKEPHEPHDNEKKKKEVIENGAFQDLLQRLGLEHYYPRKMSRANFQLIHKTSVYNTQPCSERELPFYFLQKLLMLDYGLRYLIIKHEDYTENQVYSSTSNQEKEAFDPYEDLPEESAHPTKPSAATNARLYVHPMDVQMAILHCADDFGRQYILDKLSICQFALPLLIPNPCNAQIEFSLWSLRQIRRSWQQVGKSIKEEKDNYTNQQMCRVSAPIVSFIRVGTGFSASKSQIMNCLLSERKHDVFFHRHCNGSSRDCLLMGGVVEVAWFCPGGEEQDRFDNCLTFTNLHGDAKEYEKQLAFLKEVSSIIVVLMSTSDDNKGNRKIVRDMCQSSKPLIFLLDDKGKITVNDSGSRVRIGIRNRNEAELIGELTTTIRRLLELCNTALSLENCAQVARKQGMLIDEDQRDCKEAKEKAEAIITLLREMEISQVKENLLPLQGKLWQLWCKKDKELYHLREKGNRSIEQHKSETETEKQMIRLEQLRKAFPLNALMCSVLEILQNHSETHTKLYFLQWLNVALDNLTARHLENLNEKKKALVQKEKQEAPKSSSLKDWQNEIEAISREINDCTLGIEHILREAGQIYEALEEASPMKDTLFLSLPHIAADLMISGVPIELMDGDVSYVPLKWVAAVFDKLSEKLGNKRLFVLSVLGLQSSGKSTLLNALFGLQFTLSAGRCTRGAYMQLLKVEETFTAELGFDFVLVVDTEGLRAPELSNKSQNHDNELATFVIGLGNLTLINIMGGNPSEMQDIRQIVIQAFLRMKQVKISPSCLFVHQNVREVTAKDQTMEGRRQLEERLDELAAIAAAEEQCSNVTCFSDVIKFDVNTHIYYFAHLWDGNPPMAPPNPRYSHNVQELKSRILVTAQQESRGSIMKISDVKSRVQDLWRALRNENFIFSFRNTQEVMVMSKLETMYNSWTWELRSDVQRLQDELISQIQNGKIQTLETYTLEAPVTEIYEAIKQKLEKYFNEDPDSEVLVQWKGNFENKLITLKQALILDGQRKAKELISFKKNQEKPGNKKSGYEKELLEKSRKLALSLSGTELSEEELHEEFNPLWEKWVYDVSSSLPLAVEPEIEVDYENILLDYFKKEKDIVSILKNYSGEKFEINYDKHVKMNRNFWGLTTMTIETQDIHSINMTTDCIISKVNETVNKISQQKHDYNPTYFHEILRIIHEEMKSAPTQKRYTFTRKYEIDLSLCLFQRASVKFKEMHKAFKRANDPVHYLQSKKDDFFMSFKISCQGATSIKTFVDFLWKKLTPAVSSTIRKNTALKIAGDIRTTCRAFNENRANLEKHILISLAEEENFDNYCQYLHNPESFFKNYIENHVKRYLSDTGSKKIKTFLQMSLHDIKNATLSAIHASTAIAKDKSSTVSGWLDLFCDHLGSTLTFPRKDLISIEHQEIKDIEFIKEAMSKALDPEMKKVEQNCLSKLVEEMIPEIQKMLFEHLCGCWKQCPFCKAICTNTIPTHEGDHSVPFHRPKALSGWGWYQTDHFVIEHCTSLVASDCDFVLNDGRRIPYKTYRQAGGEYATWSITPDTSTQPYWKWFVCHFRSKLEEKYHKRLFNEGEIPDAWNKITKQDVLDDLKKN", "length": 2271, "header": "tr|G5E6A5-1|G5E6A5_BOVIN Isoform 1 of VLIG-type G domain-containing protein OS=Bos taurus OX=9913 GN=LOC101903126 PE=3 SV=2 CANONICAL=G5E6A5-1" }, "locus": { "chromosome": "15", "start_pos": 46235893, "end_pos": 46229081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110646.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110646.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088434.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088434.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101903126", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101903126", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTA4-1", "protein_name": "GTPase, very large interferon inducible 1", "gene_name": "Gvin1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASAKYIPDETQLRSRRRHDLQEMLTEVGLSVDYWLPKHQEELGVTSAQALHYLDKRDLQTQQTWEKRALERLLDLSHPNSVAELHETPEEMIKTRQRQAGQALHALKALQSEGKCREEEAVRRREAELRQAMEIPEECWPVAEVSLKDITEIMEKHLSHMEQTLALSQNLSDGDLVRWASGGLALQGIYKSSHQKSLIQKREELLSVPKQFSLVGPERGMWIETKEFSSFQEQATFTHTIEMLGFSPNSLVKGEGWGLSLEAGMGQNKQTETDDTHKSHSEQSYFCSAKFSYVPLATCHFHINHLQLSKAALQELKSIEELLEQTTHPDGFPLLRHRTENFFHRFGSHANQGPLHLGGIYCWKAISEGFKSEQLDDVKKQAEESLNMYIKGSYSGFGVKVGASVNMSDSHSKTASQSTTHENLKTKVQLSVAQTGGPAEANGIAQWTAGLVASNQTWSVIDRGLQLVPIWDIILSSHRTDFKDALQVANCLKDNYTALTGLAAQIQEGEEFLTAREEARLFLEDVKCWEVSDPEEQLNTLIHFMQTLSQKIKSYTIWINTCLTDWNLQNFLISIVNFCKNVPTNIIQFIKSQLCSLLEPHVYKVTNFPGAQYIIEWTNQSESKEEDIKITSFSEFIRTLKKTHTTLMEVNFKSESPETVEEAKRTATYEVTTALSSFMKYLRETEQPDMQLLVLTIAAGAGYQLVNSIFQHLLGCNELNFLVDQMQSNQHKYQELKNICNYRAQAFLVLTALRTTVEITDISTDDKEQRLTLIKQHMGKLLSEEVAHILTKHGAHHDWENLENDLRLLIDGDYKATTPPLEMDEVKKQLQSLCHEKKQTYKQQSNDNNTKEMIENGPFLDLLQRLGLDHYYPKRMSRADFHLLYKTSVYNSQPRSEKELPFYFLQKLLMLDYGLRHLVFKNDENIKKQISIGSDDYENEDFDPYEDVIKDNDSLSYPSATESWPHIHPMDIQMAIFHCADDLTKQYILSKLSICQYALPLVVPNPNNSQIEFYLWSLRQIRKSWQESSESLQDQSYSHKNQQICRVSTPIVSFIRVGNGLSASKSQIMNSLLSKRKHDVFFHRHCRGSNKNCLMMEGVVEICWFCPAGQGEDIFDKCLTFTNLHGDAKEHCQQLTFLQDVSSLIVILMSASDNNKENQNFVRHLCQSPRPLICLIDDKEKVIANNSGKRMRIGIKNRNEAELTEELTNAIKHFLELSNTALSLEDCSQIARKQGFLIDEDQRDCKEAKEKAQIMMALLEECKLSQTKENLLPLQGQLWHLWCKKDKEFYHLREKGNRSIEQHKSEIETDKRTIRHQQLEKAFPLNDLMRSVLQLLQEYSETHNNLYFLQWLTLFFDNLTTEHLEKLHEKQRSLWLMVQREKQRAQKNSSLTLWQDQIETISTEIHDCTLGTEHLLREVGQIYEALEETSSSIENLSVCLPQIAADLMIAGVPIELMDGDASYVPLKWVAAVFDKISEKVGDKRLFVLSVLGLQSSGKSTLLNALFGLQFTVSAGRCTKGAYMQLLKVEETFTEELGFDFVLVVDTEGLRAPELNNKSKNWDHELATFVIGLGNLTLINIFGENPSEIQDILQISVQAFLRMKQVKISPSCLFVHQNVGEVTVKDQTMEGRRRLEQKLDEMTALAAKLEECSNVTQFSDVIKFDANTHVYYFAHLWDGNPPMAPPNLRYSYNVQELRNAILSTAQQESRGRILKISNVKFRVQDLWKALVTENFIFSFRNTQELLAMSKLETMYNHWTWELRSHVLDLQNQLNNQIQNGKISTLTFSLLEDPLSKKYKTIKQEFDKYFEEDPDSETLVQWKANFEHKLLILKDALISDTRRKGDEFISLKRSQETLNNQKSQYENELLERSRKLALSVNGKELTDEELYEKFNQLWTNWIHNVSSNVPHVTEPNIDLDSENILLEYFNKDKNIGERLKIKSGENFEIIYAKHIQMKKIYGVLPESLETYHKESINEITNNIDLKVTEALKNIWKQKRDYSQNYFHEILRIIENELKSEHCVKDYTFTRDYNIDLSLCLFQRASKEFKEIHEAFKSANDPVNYLERKKDDFFMSFKISCQGATSITSFVDFLWLKLTPAISVTIWEIIGPKVAGDMQATFPEFNGNRANLERHILYSLAEEENFDKYWQYLHHPEAFFRNYIRDHIRRYCLEKKGKKIKTFLKISLGDIKTAILSAIHESTAVAKDKGSTASGWLDLFCDHLGSNLVFPRRDLVSIEHQEITDTEFLKEAMSTALDPAMRKVEEDCSSKQMDEIIPDIEKILSEHLCGCWKQCPFCKAICTNTIPQHEGDHSVQFHRPQAVSGWHKHKTDYFVIDCCTSSVASNHSFILHDLQKFPYKKYREAGGDFAMWSITPDSSTQPYWKWFVCHFKSELENKYGKKFINLGSIPDLWTKITKQDVLDDLRNNTCHKYDTRWAADFSL", "length": 2440 }, "evidence": [ { "id": "G5E6A5", "url": "https://omabrowser.org/oma/group/G5E6A5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Y6R0-1", "protein_name": "GTPase, very large interferon inducible pseudo 1", "gene_name": "GVINP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESQEERAEDLEKANLAKQLLAETFQREGLDEEYWLPKLLKVLGVKSKEALKHLQYEDYLKLECEVQYPWEKMALRKLLQITDNKATVEELQKQRLEMMKQRQEEAKRALQELKEMHHSHSHSKEMIRQKEEALWQAMDIPREYWAPPEKALEDVLASIQKQLEQQEMSLGRSENVSDKEVLRRASGGLALQGIYQTSGLADMLAKREQLIRVPSGFKLAGPEQGSLLERKEFSSSAAEANFTKSMEQLGFSLSISAKARFWGFSVEGGEDYSSSSHKEDTHHSRSEQTYICTTKYHYIPTASCYFQKDQLRLSDGALRELQYTEDLLSVTQEADRLNMLKSRCARFFSRFGSHVNQGPLHFGGIFWWKASSKGFRAEQREEMKQRASEALNCFVRASFAGSVGGNVDVSKSSLQASLGRSDKGSSHTVIQLSVTNTGGPSETDSLAQWKCGLVASNTTWFVIDRGFQLIPVWDIILSNHSSDFKSAHQMSSSLRAAYEALTNHCVGTVFGEELGSAVEEARAFLERMKTWEVTADERKLLMLIDLKQDLSEKTKNPSVWINVCLSDKALQEFLVKTVLFCQKSPPENITYIKSLLQVLLDPHIYSVKDFPRASFIMQWIFKTDETDVKFPEIPHIPEIQDLIKTLLQMKEHIQEVTYSPATPVSAIHEAKIKATQTISLAVYTLLQYLQERAEKDMELLVLLVTTTIGYQVESSTFQYLLGCPEINFMAKEMQTAYDEYQSLKEQDDYRAEAFLLLTGLTITSESNEVSPERKSDRLAFMEDKMKNSWSAEIENLLKKQNVLKDWEVLERDLRSYISGQMEDTSVDLKKHSIIKDMEETLQDIPPPSPAIPKSVDSKSKTNQASANPEFLNLLKRLGLQSYYPRKMGSEDFHIIHKTSVHDSLPSKESELPFYFLQKLLSVDYSVRYLTCKDKSKPEITPAPKATEEEPSDSFDDFFSVLDERAPESATRESHVHPMDLQMAIFHCANDFMRQYISSKLAFCQFALPLLVPNPCTSQIEFPLWSLSQIKKSWKGAAKSGEQTTGSSYTNKLIYQAETPIVSFIRIGSSPSSSKSQLLNALLSKQKHNTFFHRNCKGSTKDCLLMKGVVEISWYCPHGSDDDSFDSCVAFCNLHGDARDHEPQLSFLQEISAVNVVLISESDQSDKKGRKILQDLWQSQRPLVCLFTEKENIAAGRSSQNIRIGIKNRNEAELIGELTETIQDLLEGSCTRSSLDMCLGTARQHGFLVDEDVEECVIAKEKANKLVKLLKGEKLSEIKSKLLPLQGKLWYNWCKRDRELTRLQEKGNKSIEHHRSQIERDKAAIRRKQLQKAFPLNQLMKSVLGFLRSQPASTKKYFLQWMRVFMDDLSSDRLDELKREYHQLWSQILAIKKNEEGNKAKTVMTKRLDSLSNEINDSSVGLEHILREVGQIYEALESTNSKDECILKLPEIAADLMVSGYPIELMDGDASYVPLQWVAAIFDRLIERLGDKRVFVLSVLGIQSTGKSTLLNAMFGLQFNVSAGRCTRGAFMQLIKVDENLQREVNFDYMLVVDTEGLRAIEMANKHSLNHDNELATFVIGIGNMTLINIFGENPSEMQDILQIAVQAFLRMKQVKLSPSCLFVHQNVGEITAKEQNMEGQRRLQEKLDEMTVTAAQQEFCDITCFSDVIRFDVNTHIHYFAHLWEGNPPMAPPNPTYSRNVQELKSKILQAAKKESPGSVLSLSSLKVRISDLWNALRNENFIFSFKNSVEIAAYKKLETSFSQWTWKLRRHILDLQMHLDNKVRNGELEKITTKEIENLVRETSDAITKEVQKFFSEDRDCEILIQWKSSTELKLKELKASLLDETRRKCEKLLEVKRNQSRLDERKSEYEKELLKKSRELALSLKGQELSEKELRRSFNSLWVTWVTEVSSNAPPLEKVDIDVEIESVLIEHFKEPNVAERIIKFPKRTTFTLDEKKHLSIKKLWNKLFSKISESDVSNLQHITDSIIRRVKENIDQKEKDKMDYSRTFIHEILNEVQEGMETVPSSEKYTFTTDYRIDLSVYLCRTAAARFKDMHAAFRKANNPAIYLESKREDFFQCFQISCQGATSITTFADFLCSKIAPGLRLAVYDKTALVIAERMKSEIPDFRGSRANLEACILKYLAQEEKFEKFTHYIRFPADFLESYIQTHVKTYCLDQNGRLVMFLNETLTQYYGTILKAVVASTTVVKDRRDSNKIISLWLDEFCRELGGVLTLPRSDLVGLEHLEITDIEFLNKAMMEALSPLRDHLKEEFARAGLSSFEKQPHKILVEQFAGCKEQCPFCGAVCTNTIPNHDGDHQLVFHRPEFLGGCIWYETDHLVIDICSSSVASDCSFRVGLGKWIPFLNYRDAGHPYSTWKILPDSSMQKYWKWFVSHFRTQLEEFYKGKFRGKGEIPPPWHKITKQEALDELR", "length": 2433 }, "evidence": [ { "id": "G5E6A5", "url": "https://omabrowser.org/oma/group/G5E6A5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RMQ6-1", "protein_name": "VLIG-type G domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDIIESTTDEPLLRGKKGKSLQEMLREAGLAVEYWLPKLQEHLGVTSAQALQHLEEQDLQKLKSQAQHPWEKRALDKLLNLSHSNRLSEFWESQVETRTKRQKQAEQALQELRGLLSEGRQRNAEAVRKKEAELRQAMEIPKEFWPPPENSLKEVIENMQRQLHLVEGRMAHRQNLPERELVRHASGGLALQGIYKTSDENGLIEKREELLSVPKEFSLCGPQQGTRMETKEFTSSQAESMFTETMEKLGFSVTASAKGGAWGWSLESSTDHRKHSESKETQHSQAELSYFCSTKFSYIPLASYHFPIDQLHFSKAALQELKCIEDLLGQPEDPDRLPLLRRRTEDFFRRFGSHADQGPLHLGGIYWWKAVSEGFQREQLQEVKQQSAEALDAYVTGSYSGFGVNVAAGVDVSDAHSKTGSQRANVQNLQTKVQLSVAHTGGPPEANSLLEWKAGLVASNQTWCVIDRGLQLVPIWDMILFNHRSDFKDPLQVANCLKDSYAALTGLTAQVQEGEELLSAQEEARVFLEDVRSWEVSDPEEQLKKLRNFRQTLSHKTKSHDTWTNICLTDSGLQNFLVNTVNFCRKSSISETKFIKSQLRSLLDPHVYRGSNFPQVHSIMQWIYQPEPEQEHVTITQFSELIETFKKTQDDLLEVKATSESTESVEEAQRKATYEVSMSLGCFFNHLQEMGQADTYILLLSIAAGAGYHVVNNTFQCLLGYDDIDFLLHTMQTAQDKYQELKTICDYRAQAFLVLTGLTATAGIKAVSPEEKKQRLALIRHHMGQSFSKEVIHVLTKAGTGPNWEILEKDLRLLVDGDYEATVPSLQMEEVRKQLQSLLHEDKEPRELHDDENNRPEVMENGAFLELLQRLGLEHSYPKKMSRSNFHLIHKTSVYNTQPCSERELPFYFLQKLMMLDYGLRYLVIRDEEYTEEQVCSSNTGQENADFDPYEDLVEDKDGPTRPSATAVKPHVHPMDIQMAILHCADDFARQYILAKLAICQFALPLLIPHPCNAQIQFSLWSLRQIRRSWQQAGKPTEQEKDNYKNQQMCRVSTPIVSFIRVGKGFSASKSQIMNSLLSQRKHDVFFHRHCKGSSRDCLLMAGVVEVTWFCPGAGDEDRFDNCLTFTNLHGDAKEHKQQLTFLQEVSSLIVVLMSTSDDNQESRKVVRALCQSPKPLICLLDDKEKAMSSTSGPRVRIGIRNRNEAEFIEELATTIRGLLKASDTALSLENCAQVARKQGMLIDEDQEDCKEAKTKAEVLMALLEDMEIAQMKENLLPLQGELWQLWCKKDKELYHLREKGNRSIEQHKSDIETDKQMIRLRQLRKAFPLNDLMHSVLGILQKHSETHTKLYFLQWLSVFLDNLTAGHLEKLNEKKKQLWSRVQKEKREAQKSSSLKGLQNELEAISRKISDCTLGVEQILRELGQIYEALEEGFSTKDVSFLSLPHMAADLMLSGVPIELMDGDASYVPLRWVAAVFDKVSEKLGDKRLFVLSILGLQSSGKSTLLNAMFGLQFTVSAGRCTRGAYMQLLKVEETFTDELGFDFLLVVDTEGLRAPELSNKSQNHDNELATFVIGLGNLTVINIFGENPSEMQDILQIAVQAFLRMKQVKISPSCLFVHQNVGEVTAKDQTMEGRRRLEQRLDEMAATAAEEEQCSDVGRFSDVIKFDVNTHVYYFAHLWDGNPPMAPPNPRYSHNAQELKSRILATAKQEARGSIMKISDVKFRVQDLWKALLNENFVFNFRNTREVTAMSKLETMYNKWTWELRSHVLSLQDQLINQIQNGKIHTLEAHTLAAPVTDKYEAIKQELEKYFSEDPDSEVLVQWKGNFENKLMILKESLISDSQRKAKELLRFKKNQEKLDNKKSGYEKELLEKSRNLALTVKGTEWSEEELREKFNPLWKKWVYNVSSTLPPVTEPAIEVDAENILLDYFKKERKMVDKLKKDWGKEFMIKYDKHVQMKTKYWNLFKMTLEAQDEASIHMTTDCILSKFNEMINNICRQKHDYDPIYFHEILKIIDEEVKSAPTQERYTFTRNYEIDLSLCLFQRASVKFKEMHKAFKRANDPVNYLESKKDDFFMSFKISCQGATSIKTFVDFLWNKLTPAVSNTIRKKMAPQIAGDMRATCPAFSGNRSNLEKHILISLAQEENFNNYWQYLHNPQSFVKNYIENQIKSYCSDKGSEKMKTFLKMSLDAIKNDILSAIHEATEIAKDKRSTASGWLDLFCDKLRSDLIFPRKDLISIEHQEIKDMEFLKEAMCKALDPEMNRVEQNCLYMPVEEMVPEIQKMLSEHLSGCWKQCPCCRAICTNTIPTHDGDHSVPFHRPQAVSGISWYKTNNFVLDYCTSLVASDCFLVFDDGRQIPYKNYRQAGGDYATWSITPDTSAQPYWKWFVCHFRSKLEEKYQKRFIDKGKIPDAWEKITKQNVLDDLK", "length": 2429 }, "evidence": [ { "id": "G5E6A5", "url": "https://omabrowser.org/oma/group/G5E6A5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80SU7-1", "protein_name": "Interferon-induced very large GTPase 1", "gene_name": "Gvin1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATAKCFTDEPQLQSRRKHNLQEMLTEVGLSVDYWLPKLQEDLGVTSAQALQYLDRNDLQKLKSQTTHTWEKRALEKLLDFSQPNSVAELQETPREMKKNRQRQAGQALQALKALQSEGKHREEEAVRRKEAELRQAMEIPEECWPTAEVSLKDITEIMERHLSHMERTLAHSPNLSDGDLVRWASGGLALQGIYKTNHPRSLIQKREELLSVPKQFSLVGPEHGTEIKTMEFSSFHEQAMFTETIKMMGFSSTSLVKGEGWGFSLEAGIDQNEQTASENTHQSHSEQTYFCSARFSYIPLATCHFHINDLELSNAALQELKTIEELLEQTTDHRDGLPLLRHRAENFFHRFGSHANQGPLQLGGIYCWKAISEGFKSEHLADVKQQTRESLNIYIMGSYSGFGVKVGASVNIANSNSETASFSTTHLHSQTKVQLSVAQIGGPAEADGIAQWTAGLVVSNQTWSVIDRELQLVPIWDIILSSHRTDFKNALQVANCLKDNYTALTELDAQIQEGEEFLTARKEAKLFIEDVKCWEVSDPEEQLTKLLDFMQTLSQKIKSYNIWINTCLTDWDLQNFLINTVKFCKTSPTYKTQFIKSQLCILLEPHVYKVTNFPEAHSIIQWINQSEYGEEQVKITSFSEFIKTLKKTHKYLMEVNFKNEAPETVEEAERTATYEVTTALSSFLKYLKETEQPDMQLLLLSIAAGAGYQLVNSIFQHLLGCDELNFLLDQMQSNQHKYQELKNICNYRAQAFLVLTALRTTVEITDISTEEKRQRLALIKQHMGTLLSEEVAHVLTKHGEHHDWESLENDLRLLIEGDYKATTHYLQMDEVKKQLQSLCHGKKQTYKQKSNENITKGMIENGPFLKLLQRLGLDNYYPKRMSRADFHLIYKTSVYNSQPRSEKELPFYFLQKLLMLDYGFRHLIVKDDENIKKQISIGSSNHENEDIDPYDDVIIDNDSPGYPSATESWPHIHPLDIQMTILHCADDLTRQYIFSKLSICHYALPLVVPNPNTSQIEFYLWSLRQIRKSWQDASKSPQDKSYSHRNQQMCRVSTPIVSFIRVGNDLSASKSQIMNSLLSKRKHDVFFHRHCKGSNKHCLLMQGVVEICWFCPAGQGEDTFENCLTFTSLHGDAKEHTQQLSFLQHVSSIIVVLMSVSDNNKENQKLVRHLWQSSTPLICLIDDKEKAIANTSGKRMRIGIKNRNEAELTEELTNAIKHFLELSNTVLSLEDCSQTARELGFIIDEDQRDCKEAKEKAQTVMALLEEYKLSQTKENLLPLQGQLWHLWCKKDKEFYHLREKGNRSIEQHKSEIETHKRKIRRQQLEKAFPLNDLMRSVLELLQDYSETHNKLYVLQWLTLFFDNLTIDHLDKLHERQRSLWLRIQTEKQRAQKSNSVQNQIEAISTEIHNCTLGIEHLLREVGQIYEALEETSSSRDSLFLCLPQIAADLMIAGVPIELMDGDASYVPLKWVAAIFDKITEKVGDKRLFVLSVLGLQSSGKSTLLNALFGLQFTVSAGRCTKGAYMQLLKVEETFTEELGFNYVLVIDTEGLRAPELNNKSQNWDHELATLVIGLGNLTLINIFGENPSDIQDILQISVQAFLRMKQVKISPSCLFVHQNVGEVTAKDQTMEGRKRLEQKLDEMTALAAELEECSNITRFSDVIKFDANRHVYYFAHLWDGNPPMAPPNPRYSYNVQELRNEILSTAQQESRGRILKISDFKFRVQDLWKALVSENFIFSFRNTQEVIAMSKLETKYNEWTWELRSHVLDLQNQLDNQIQNGKILTLTSNLLEEPLSRKLKTIKEEFDKYFEEDPDCEILVQWKANFEHKLLILKDSLISDTRQKCNEHISLKNSQEILDNQKSQYENQLLERSRKLALNLKGKELSDEELHEKFRQLWTSWIYDVSSNVPHVTEPNIDLDSENILLEYFKKDKNIVERLKIKSQGKFEIMYDKHIQMKKKYLLLRKSLETCHVESIKKTTNNIQLKFTETLTNIWKQKRDYSQNYFHEILRIIENELKSEPCEGDYTFTKDYIIDLSLYLFQRASKDFKKMHAAFKTANDPVNYLERKKDDFFMSFKISCQGATSITSFVDFLWLKLTPAISVSIWKIMVQKIAGDMRATCPEFNGNRANLEIHILYSLAEEEKFDKYWKYIQKPEEFFRDYIRDHIKRYCSEKESEKIKTFLNISLGDIKNTILSAIHNSTKVAKAKGSTASHWLDLFCDHLGSNLVFPRKDLVSIEHQELMDTEFLKEAMSKALDPAMREVEEDCSSKHIDEIVPDIEKILSEHLCGCWKQCPFCKAICTNTIPQHEGDHSVPFHRPQAVSGWHWHKTDQFHINVCTSSVASNISFILDGFREFPFKKYREAGGDYATWSITPDSSTQPYWKWFVCHFRSNLEENYGKKFTGKGSLPDLWTKITKQEVLNDLKK", "length": 2427 }, "evidence": [ { "id": "G5E6A5", "url": "https://omabrowser.org/oma/group/G5E6A5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "G5E6A5", "url": "https://www.uniprot.org/uniprotkb/G5E6A5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E6A5", "url": "https://www.uniprot.org/uniprotkb/G5E6A5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E6A5", "url": "https://www.uniprot.org/uniprotkb/G5E6A5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1145, "end_pos": 1147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1186, "end_pos": 1188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1206, "end_pos": 1208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1401, "end_pos": 1403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1419, "end_pos": 1421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1498, "end_pos": 1500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1784, "end_pos": 1786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1821, "end_pos": 1823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1832, "end_pos": 1834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2036, "end_pos": 2038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6A5" }, { "id": "PS51717", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51717" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VLIG-type G", "eco_id": "ECO_0000259", "start_pos": 1327, "end_pos": 1568, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1033, "end_pos": 1035 }, { "start_pos": 1145, "end_pos": 1147 }, { "start_pos": 1186, "end_pos": 1188 }, { "start_pos": 1206, "end_pos": 1208 }, { "start_pos": 1401, "end_pos": 1403 }, { "start_pos": 1419, "end_pos": 1421 }, { "start_pos": 1498, "end_pos": 1500 }, { "start_pos": 1784, "end_pos": 1786 }, { "start_pos": 1821, "end_pos": 1823 }, { "start_pos": 1832, "end_pos": 1834 }, { "start_pos": 2036, "end_pos": 2038 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 886, "end_pos": 888 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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homeostasis protein cutC homolog OS=Bos taurus OX=9913 GN=CUTC PE=3 SV=2 CANONICAL=H7BWV5-1" }, "locus": { "chromosome": "26", "start_pos": 20714320, "end_pos": 20681638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090971.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090971.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101789.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101789.2" } ] } }, { "isoform_ac": "H7BWV5-1", "url": "https://www.uniprot.org/uniprotkb/H7BWV5/entry", "sequence": { "sequence": "MRASGRTRLSGCARWNPDSLSGNRRSTRDERVEHEEAGGLLRAEAGADTIREGAANGFLMEVCVDSVESAVNAERGGAGRIELCSGLLEGGTTPSMGVLQVVKQYVQIPVFVMIRPRGGDFLYSDREVEVMKADIRLAKLYGADGLVFGALTEDGHIDKELCMSLVALCRPLPVTFHRAFDMVHDPVAALETLLTLGFERVLTSGCDSSALEGLPLIKRLIDQAKGRIVVMPGGGITDRNLQRILEGSGATEFHCSARSARDSGMKFRNSSVAMGASLSNSEYSLKVTDVTQVRTLNAIAKNILV", "length": 305, "header": "tr|H7BWV5-1|H7BWV5_BOVIN Isoform 1 of Copper homeostasis protein cutC homolog OS=Bos taurus OX=9913 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"MSARCCAGQLACCCGNAGCSYCCGPKVRQSRSTRFMYALYFILVVIICCIMMSNTVANEMREHIPYFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLNINNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAVGGFLFIVIQLLLLVEFAHKWNKNWTAGTATNKLWYASLSLVTLITYSITTGGLIWMAVFYTQKDGCMENKILLGVNGGLCLLMSVVSISPSVRDRQPHSGILQSGLISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPNFGQDLYRDKTLVAGLGTAILCVCILYSCLTSTTRSSSDALQGRYTAPELEVARCCFCFGSGGEDAEEKRNMKEGPRVIYDEKKSTVYSYAYFHFMFFLASLYVMMTVTNWFNYESANIETFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQYSV", "length": 459, "header": "tr|A0A3Q1LF32-1|A0A3Q1LF32_BOVIN Isoform 1 of Serine incorporator 5 OS=Bos taurus OX=9913 GN=SERINC5 PE=3 SV=1 CANONICAL=A0A3Q1LF32-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LF32-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32/entry", "sequence": { "sequence": "MSARCCAGQLACCCGNAGCSYCCGPKVRQSRSTRFMYALYFILVVIICCIMMSNTVANEMREHIPYFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLNINNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAVGGFLFIVIQLLLLVEFAHKWNKNWTAGTATNKLWYASLSLVTLITYSITTGGLIWMAVFYTQKDGCMENKILLGVNGGLCLLMSVVSISPSVRDRQPHSGILQSGLISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPNFGQDLYRDKTLVAGLGTAILCVCILYSCLTSTTRSSSDALQGRYTAPELEVARCCFCFGSGGEDAEEKRNMKEGPRVIYDEKKSTVYSYAYFHFMFFLASLYVMMTVTNWFNYESANIETFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQYSV", "length": 459, "header": "tr|A0A3Q1LF32-1|A0A3Q1LF32_BOVIN Isoform 1 of Serine incorporator 5 OS=Bos taurus OX=9913 GN=SERINC5 PE=3 SV=1 CANONICAL=A0A3Q1LF32-1" }, "locus": { "chromosome": "10", "start_pos": 11216646, "end_pos": 11112660, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072137.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072137.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056665.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056665.1" } ] } }, { "isoform_ac": "A0ABI0NW40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW40/entry", "sequence": { "sequence": "MSARCCAGQIPYFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLNINNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAVGGFLFIVIQLLLLVEFAHKWNKNWTAGTATNKLWYASLSLVTLITYSITTGGLIWMAVFYTQKDGCMENKILLGVNGGLCLLMSVVSISPSVRDRQPHSGILQSGLISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPNFGQDLYRDKTLVAGLGTAILCVCILYSCLTSTTRSSSDALQGRYTAPELEVARCCFCFGSGGEDAEEKRNMKEGPRVIYDEKKSTVYSYAYFHFMFFLASLYVMMTVTNWFNYESANIETFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQYSV", "length": 405, "header": "tr|A0ABI0NW40-1|A0ABI0NW40_BOVIN Computationally mapped isoform of Serine incorporator 5 OS=Bos taurus OX=9913 GN=SERINC5 PE=3 SV=1 CANONICAL=A0A3Q1LF32-1" }, "locus": { "chromosome": "10", "start_pos": 11216646, "end_pos": 11112660, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136220.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136220.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105809.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105809.1" } ] } }, { "isoform_ac": "F1N5T9-1", "url": "https://www.uniprot.org/uniprotkb/F1N5T9/entry", "sequence": { "sequence": "MSARCCAGQLACCCGNAGCSYCCGPKVRQSRSTRFMYALYFILVVIICCIMMSNTVANEMREHIPYFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLNINNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAVGGFLFIVIQLLLLVEFAHKWNKNWTAGTATNKLWYASLSLVTLITYSITTGGLIWMAVFYTQKDGCMENKILLGVNGGLCLLMSVVSISPSVRDRQPHSGILQSGLISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPNFGQDLYRDKTLVAGLGTAILCVCILYSCLTSTTRSSSDALQGRYTAPELEVARCCFCFGSGGEDAEEKRNMKEGPRVIYDEKKSTVYSYAYFHFMFFLASLYVMMTVTNWFNYESANIETFFSGSWSIFWVKMASCWICVLLYLEFNSTGVLNHQINWNLRDDGLPRWHSGKESACQCRRH", "length": 480, "header": "tr|F1N5T9-1|A0A3Q1LF32_BOVIN Computationally mapped isoform of Serine incorporator 5 OS=Bos taurus OX=9913 GN=SERINC5 PE=3 SV=4 CANONICAL=A0A3Q1LF32-1" }, "locus": { "chromosome": "10", "start_pos": 11216646, "end_pos": 11106851, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002123.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002123.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002123.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002123.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504658", "resource": "KEGG Pathway" }, { "id": "R-BTA-977347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977347", "resource": "Reactome", "description": "Serine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1P8B1A7-1", "protein_name": "Serinc-domain containing serine and sphingolipid biosynthesis protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNGSAEATRTRPLQISPGDLEAAHLDELIMEIEQRSLYYYQEKNKSLRARYTYGTIFLIINLCAWFIRDYAQKALALLPYVSSCGPEGSRCFHTLGVLRVSLGCFIFYFVMFLSTWNTMKLHEAQNSWHSDNWIFKFFLLVIVMVASFFIPQLYIQIYGEIARVGAGIFLGLQLVSVIEFITWWNNYWMPQNQSKQSCSFGLVMSIVFYIGSVCGIAVMYYFYGASTACGLNIFFISWTVILLIVMMVISLHSKVKNRGLLSSGIMASYIVFLCWSAIRSEPSHTKCNAHTQNSHTDWTTILSFLIAIGAIVMATFSTGIDSESFRFEFRKDEAKEEDDIPYSYGFFHLVFSLGAMYFAMLFISWNLSHSTEKWSIDVGWTSTWVKIVNEWFAAAIYLWKLIAPIVRQHRVHEQPQPTAAEVHR", "length": 424 }, "evidence": [ { "id": "A0A3Q1LF32", "url": "https://omabrowser.org/oma/group/A0A3Q1LF32/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A4X1T661-1", "protein_name": "Serine incorporator 5", "gene_name": "SERINC5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAQCCAGQLACCCGNAGCSFCCGCCPKIRQSRSTRFMYALYFILVVILCCIMMSNTVANEMRERIPFFEDICKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNAWRYVGAIGGFLFIGIQLLLIVEFAHKWNKNWTAGTATNKLWYACLSLVTLIMYSIATGGLILMAVFYTQKDGCMENKILLGVNGGLCLLISVVAISPCVQDRQPHSGLLQSGLISCYVTYLTFSALSSKPVEVVLDEHGKNVTICVPDFGQDLYRDKNLVAGLGTSLLCACILYSCLTSTTRSSSDALQGRYGAPELEVARCCFCFSSGGEDTEEQQNVKEGPRVIYDEKKSTVYTYSYFHFVFFLASLYVMMTITNWFNYESANIESFFSGSWSIFWVKMASCWICVLLYLGTLIAPLCRPSPQFSV", "length": 461 }, "evidence": [ { "id": "A0A3Q1LF32", "url": "https://omabrowser.org/oma/group/A0A3Q1LF32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q63175-1", "protein_name": "Serine incorporator 5", "gene_name": "Serinc5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSARCCAGQLACCCGSAGCALCCGCCPKFRQSRSTRFMYLFYFTLVIIPCCVMMSPSVMKQMTEHIPFFEDFCKGIKAGDTCENLVGYSAVYRVCFGMACFFFVFCVLTFKVNNSKSCRASIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNVWRYVGAVGSFFFICIQLLLIVEFAHKWNKNWTAGTVRNKLWYASLSLALIMYSIAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLAAISPCVQNRQPHSGLLQPGLISCYVTYLTFSALTSKPEKVVKDEHGKNVTICVPDFGQDFRRDESMVTWLGTLLLVVCISYSCLTSTTRSSSDALQRRYGAPELEVARCCFCFGPDGEDTEEQQNVKEGPRVIYDEKKGTVYSYSYFHFVLLLASLYVMMTLTSWFHYENATIETFFVGSWSIFWVKMASCWMCVLLYLWTLVAPLCCPSRQFSV", "length": 460 }, "evidence": [ { "id": "A0A3Q1LF32", "url": "https://omabrowser.org/oma/group/A0A3Q1LF32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q803X0-1", "protein_name": "Serine incorporator 5", "gene_name": "serinc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCTPCCVSQLACCCGSAACSLCCGCCPKIKQSTSTRFMYALFFMLVTVTCVIMMSPTVEMAMREHIPFYSQMCQQLNAGENCSTLVGYSAVYKVCFGMACFFFFFAVFTIRVQNSTGCRAAVHNGFWFFKFVALLACCAGGFFLPNQDQFLEVWRYVGAAGGFLFIIIQLMLLVQFAHRWNQNWSSGATYNKLWYAALALVTLVLFSVAVGGMVFMFMYYTHPEACFLNKIFLGVNGGLCFIVSLLAISPCIQTFQPTSGLLQPAVITLYVMYLTFSALASKPIEMVEDEIKGNITVCVFPFKSGLKSDTNIVTGVGTAILFCCILYSCLISTTKRSSAALQVYRNDMPENERARCCFCWVDDTEDYDDEKTSGGQNVKYDERDGTVYSYCFFHFVFFLGSLYVMMTVTNWFHYDNAKIERLLEGSWSVFWIKMASSWVCLFFYMWTLVVPMLFPQRFQA", "length": 460 }, "evidence": [ { "id": "A0A3Q1LF32", "url": "https://omabrowser.org/oma/group/A0A3Q1LF32/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86VE9-1", "protein_name": "Serine incorporator 5", "gene_name": "SERINC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAQCCAGQLACCCGSAGCSLCCDCCPRIRQSLSTRFMYALYFILVVVLCCIMMSTTVAHKMKEHIPFFEDMCKGIKAGDTCEKLVGYSAVYRVCFGMACFFFIFCLLTLKINNSKSCRAHIHNGFWFFKLLLLGAMCSGAFFIPDQDTFLNAWRYVGAVGGFLFIGIQLLLLVEFAHKWNKNWTAGTASNKLWYASLALVTLIMYSIATGGLVLMAVFYTQKDSCMENKILLGVNGGLCLLISLVAISPWVQNRQPHSGLLQSGVISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPDFGQDLYRDENLVTILGTSLLIGCILYSCLTSTTRSSSDALQGRYAAPELEIARCCFCFSPGGEDTEEQQPGKEGPRVIYDEKKGTVYIYSYFHFVFFLASLYVMMTVTNWFNHVRSAFHLLP", "length": 423 }, "evidence": [ { "id": "A0A3Q1LF32", "url": "https://omabrowser.org/oma/group/A0A3Q1LF32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHJ6-1", "protein_name": "Serine incorporator 5", "gene_name": "Serinc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSARCCAGQLACCCGSAGCSLCCGCCPKFRQSRTTRFMYLFYFILVIALCCVMMTPSVMKQVKDHIPFFEEFCKKTQAGGDACENLVGYSAVYRVCFGMACFFALFCLLTLKVNNSKSCRAYIHNGFWFFKLLLLGAMCSGAFFIPDQETFLKVWRYVGAGGSFLFICIQLLLIVQFAHKWNKNWTAGTVRNKLWYASLSLVTLIMYSVAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLVAISPCVQNRQPHSGLLQSGLISCYVTYLTFSALTSKPEKKVLDEHGKNVTICAPDFGQDLHRDENMVTWLGTLLLIVCISYSCLTSTTRSSSDALQSRYGAPELEVARCCFCFGPDGEDTEEQQNVKKGPRVIYDEKKGTVYSYSYFHFVFFLASLYVMMTLTSWFHYENATIKTFFSGWSVFWVKMASCWMCVLLYLQTLVAPLCCPSRQFSV", "length": 461 }, "evidence": [ { "id": "A0A3Q1LF32", "url": "https://omabrowser.org/oma/group/A0A3Q1LF32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" }, { "name": "myelin sheath", "id": "GO:0043209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043209", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF32", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "38571", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38571", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38571" } ] }, { "id": "38663", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MUP9-1" ], "evidence": [ { "id": "38663", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38663" } ] }, { "id": "38895", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38895", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38895" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MUP9", "gene_name": "VAT1", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "F1MUP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUP9" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "F1MUP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUP9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 292, "end_pos": 294 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"common_name": "Mouse" }, { "uniprot_canonical_ac": "P18421-1", "protein_name": "Proteasome subunit beta type-1", "gene_name": "Psmb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSTAAYRDPDRELVMGPQGSAGPVQMRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVPLRKD", "length": 240 }, "evidence": [ { "id": "G5E589", "url": "https://omabrowser.org/oma/group/G5E589/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20618-1", "protein_name": "Proteasome subunit beta type-1", "gene_name": "PSMB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD", "length": 241 }, "evidence": [ { "id": "G5E589", "url": "https://omabrowser.org/oma/group/G5E589/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23724-1", "protein_name": "Proteasome subunit beta type-6", "gene_name": "PRE7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MATIASEYSSEASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD", "length": 241 }, "evidence": [ { "id": "G5E589", "url": "https://omabrowser.org/oma/group/G5E589/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40304-1", "protein_name": "Proteasome subunit beta type-1", "gene_name": "Prosbeta6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRLGFEQFPDYQVPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDTFISAAERDIYTGDSVLINIITKDGIEVRTLTLRQD", "length": 235 }, "evidence": [ { "id": "G5E589", "url": "https://omabrowser.org/oma/group/G5E589/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P42742-1", "protein_name": "Proteasome subunit beta type-1", "gene_name": "PBF1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTKQHANWSPYDNNGGTCVAIAGSDYCVIAADTRMSTGYSILSRDYSKIHKLADRAVLSSSGFQADVKALQKVLKSRHLIYQHQHNKQMSCPAMAQLLSNTLYFKRFFPYYAFNVLGGLDEEGKGCVFTYDAVGSYERVGYGAQGSGSTLIMPFLDNQLKSPSPLLLPKQDSNTPLSEAEAVDLVKTVFASATERDIYTGDKLEIMILKADGIKTELMDLRKD", "length": 223 }, "evidence": [ { "id": "G5E589", "url": "https://omabrowser.org/oma/group/G5E589/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6DRF3-1", "protein_name": "Proteasome subunit beta type-1", "gene_name": "psmb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MISAQAYGENGKMKEYHYTGPVEHKFSPYAFNGGTVLAVAGEDFAIVASDTRLSEGYSIHSRDSPKCYKLTDTTVLGCSGFHGDCLTLTKIIEARLKMYKHSNNKSMTSGAIAAMLSTILYGRRFFPYYVYNIIGGLDEEGRGAVYSFDPVGSYQRDTYKAGGSASAMLQPLLDNQIGFKNMENVEHVPLTQEKAVQLVKDVFISAAERDVYTGDALKVCIVSKEGIKEEIVPLRKD", "length": 237 }, "evidence": [ { "id": "G5E589", "url": "https://omabrowser.org/oma/group/G5E589/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86A21-1", "protein_name": "Proteasome subunit beta type-1", "gene_name": "psmB1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METLKLSALPEKDKQQPISHGRFEAYVDNGGTVLAVAGKDYCVIAGDTRMSDGGYGIQTRKYTKIFQLTKKCVLATSGMQADTIALQKRLKSMLESFEKEHGKPMSTPAIAQFLSNTLYYKRFFPYYTFNLVAGVDEQGEGWIWTYDAVGSHERVKYSSQGSGNQLVIPLLDNQVAKFNQQIVEGNKDVSCEQVVSFVKDSITSAGERDIYTGDFADIVVVDKNGVHWEKFELKLD", "length": 236 }, "evidence": [ { "id": "G5E589", "url": "https://omabrowser.org/oma/group/G5E589/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" }, { "name": "proteasome core complex", "id": "GO:0005839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005839", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" }, { "name": "regulation of proteasomal protein catabolic process", "id": "GO:0061136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061136", "evidence": [ { "database": "UniProtKB", "id": "G5E589", "url": "https://www.uniprot.org/uniprotkb/G5E589" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E589-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 241, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E589-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E589" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5B8-1", "uniprot_ac": "G5E5B8", "uniprot_id": "G5E5B8_BOVIN", "mass": { "chemical_mass": 71549.0, "monoisotopic_mass": 71549.0 }, "refseq": { "ac": "NP_001179816", "name": "junctophilin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179816" }, "gene_names": [ { "name": "JPH1", "type": "recommended", "evidence": [ { "id": "G5E5B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ] }, { "name": "JPH1", "type": "synonym", "evidence": [ { "id": "NP_001179816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179816" } ] } ], "protein_names": [ { "name": "Junctophilin", "type": "recommended", "evidence": [ { "id": "G5E5B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5B8/entry#names_and_taxonomy" } ] }, { "name": "junctophilin-1", "type": "synonym", "evidence": [ { "id": "NP_001179816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179816" } ] } ], "function": [ { "annotation": "Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8#function" }, { "database": "UniProtKB", "id": "PIRNR037387", "url": "https://www.uniprot.org/uniprotkb/PIRNR037387#function" }, { "database": "UniProtKB", "id": "A0A3Q1LYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYZ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "JPH1", "url": "https://www.uniprot.org/uniprotkb/G5E5B8", "locus": { "chromosome": "14", "start_pos": 37502881, "end_pos": 37595397, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008842", "url": "https://www.ensembl.org/id/ENSBTAG00000008842" } ] } } ], "crossref": [ { "id": "G5E5B8", "url": "https://alphafold.ebi.ac.uk/entry/G5E5B8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008842", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008842", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536811", "url": "https://www.ncbi.nlm.nih.gov/gene/536811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536811", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQDKRSA", "url": "https://omabrowser.org/oma/group/NQDKRSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5B8", "url": "https://www.orthodb.org/?gene=G5E5B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23085", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23085", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23085:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23085:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179816", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5B8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGTRGGFVLNFHADAELSGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTEIYMGEWKNDKRTGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYIKQRFQEGVDAKENPEDKVPEKPPTPKESPHFYRKGTTPPESPEPSPRQGRSPSPKPARKQNPSSGARFNQDRRSAAEEKVTAAVNKPLTSKAPPKEVGAVVPSSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHPPEDTEEEGSSQSSSALVHKPSPNKWSPPKSVTKPVAKESKAEPKAKKSELAIPKNPASSDARPALEKEANSGPNSIMIILVMLLNIGLAILFVHFLT", "length": 658, "header": "tr|G5E5B8-1|G5E5B8_BOVIN Isoform 1 of Junctophilin OS=Bos taurus OX=9913 GN=JPH1 PE=3 SV=1 CANONICAL=G5E5B8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LYZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYZ5/entry", "sequence": { "sequence": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGTRGGFVLNFHADAELSGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTEIYMGEWKNDKRTGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYIKQRFQEGVDAKENPEDKVPEKPPTPKESPHFYRKGTTPPESPEPSPRQGRSPSPKPARKQNPSSGARFNQDRRSAAEEKVTAAVNKPLTSKAPPKEVGAVVPSSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHPPEDTEEEGSSQSSSALVHKPSPNKWSPPKSVTKPVAKESKAEPKAKKSELAIPKNPASSDARPALEKEANSERMVSKKKTRKKKSQRTSS", "length": 651, "header": "tr|A0A3Q1LYZ5-1|A0A3Q1LYZ5_BOVIN Computationally mapped isoform of Junctophilin OS=Bos taurus OX=9913 GN=JPH1 PE=3 SV=1 CANONICAL=G5E5B8-1" }, "locus": { "chromosome": "14", "start_pos": 37595198, "end_pos": 37506357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076976.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076976.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060889.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060889.2" } ] } }, { "isoform_ac": "G5E5B8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5B8/entry", "sequence": { "sequence": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGTRGGFVLNFHADAELSGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTEIYMGEWKNDKRTGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYIKQRFQEGVDAKENPEDKVPEKPPTPKESPHFYRKGTTPPESPEPSPRQGRSPSPKPARKQNPSSGARFNQDRRSAAEEKVTAAVNKPLTSKAPPKEVGAVVPSSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHPPEDTEEEGSSQSSSALVHKPSPNKWSPPKSVTKPVAKESKAEPKAKKSELAIPKNPASSDARPALEKEANSGPNSIMIILVMLLNIGLAILFVHFLT", "length": 658, "header": "tr|G5E5B8-1|G5E5B8_BOVIN Isoform 1 of Junctophilin OS=Bos taurus OX=9913 GN=JPH1 PE=3 SV=1 CANONICAL=G5E5B8-1" }, "locus": { "chromosome": "14", "start_pos": 37595198, "end_pos": 37505354, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011643.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011643.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011643.4", "url": "https://www.ensembl.org/id/ENSBTAP00000011643.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536811", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQ55-1", "protein_name": "Junctophilin", "gene_name": "Jph1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADNPAGTRGGFVLNFHADTELGKKKSGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAAVAARQECDIARAVARELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSPKESPHFYRKGTTPPRSPEASPKQSHSPQPSSPKSMKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATVSKYSGRHYVPNPSNGELHSQYHGYYVKLNTPQHPPEDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTASNDTCPPLEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "length": 660 }, "evidence": [ { "id": "G5E5B8", "url": "https://omabrowser.org/oma/group/G5E5B8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ET80-1", "protein_name": "Junctophilin-1", "gene_name": "Jph1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHEAAAAAADSPAGTRGGFVLNFHADTELGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRNTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYIKQRCQEGGDIKENPEEKVLEKPPSPKESPHFYRKGTTPPRSPESSPKQSHSPQPSSPEPSKKQNPSPGARLSQDKQSLAEEQVTAFVNKPSMSKAPAKELGASVSKYSGRHHVPNPSNGELHSQYHGYYVKLNTPQHPPEDREDDRGVSQSSSALVPRPSPNKWGPPKSVTKPVAKESKTEPKAKKSELAIPKNPASNDTCPSLEKEANSGPNSIMIVLVMLLNIGLAILFVHFLT", "length": 660 }, "evidence": [ { "id": "G5E5B8", "url": "https://omabrowser.org/oma/group/G5E5B8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" }, { "name": "junctional sarcoplasmic reticulum membrane", "id": "GO:0014701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014701", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" }, { "name": "junctional membrane complex", "id": "GO:0030314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030314", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "G5E5B8", "url": "https://www.uniprot.org/uniprotkb/G5E5B8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5B8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 658, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5B8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5B8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 254, "end_pos": 256 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5C4-1", "uniprot_ac": "G5E5C4", "uniprot_id": "G5E5C4_BOVIN", "mass": { "chemical_mass": 208571.0, "monoisotopic_mass": 208571.0 }, "refseq": { "ac": "XP_024841416", "name": "protein RRP5 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841416" }, "gene_names": [ { "name": "PDCD11", "type": "recommended", "evidence": [ { "id": "G5E5C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" } ] }, { "name": "PDCD11", "type": "synonym", "evidence": [ { "id": "XP_024841416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841416" } ] } ], "protein_names": [ { "name": "Protein RRP5 homolog", "type": "recommended", "evidence": [ { "id": "G5E5C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C4/entry#names_and_taxonomy" } ] }, { "name": "Programmed cell death protein 11", "type": "synonym", "evidence": [ { "id": "G5E5C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C4/entry#names_and_taxonomy" } ] }, { "name": "protein RRP5 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024841416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841416" } ] } ], "function": [ { "annotation": "Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. 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"https://bgee.org/?page=gene&gene_id=ENSBTAG00000009715", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05693", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05693", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05694", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05694", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05695", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05695", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05696", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05696", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05697", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR048059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GQYLRAY", "url": "https://omabrowser.org/oma/group/GQYLRAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5C4", "url": "https://www.orthodb.org/?gene=G5E5C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23270", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23270", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23270:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23270:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024841416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841416", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5C4", "url": "https://www.uniprot.org/uniprotkb/G5E5C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5C4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5C4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAMEESFPRGGTRKTHKSEKAFQQSVEQDNLFDISTEEESTKRKKIQKGPAKTKKLKVETRQSSKFVREKFEILNVESLCEGMRILGCVKEVNELELAISLPNGLQGYVQVTEICDAYTEKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLDTTKGSKKNVMLSLNPKNVNRVLSAETLKPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNKGAKLKVGQYLNCLIEEVKGSRGVVTLSIGHSEVSAAIATEEQSWTLNSLLPGLVVKAQVQKVTPLGLTLKFLSFFSGLVDFMHLDPKKAGTYFSNQQVRACVLCVHPRTRAVRLSLRPVFLQPGRPLTRLLCQQLGAVLDDVPVQGFFGSAGATFKLKDGTLAYARRNHLSNSKKTFKPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYHDIKPGALVKGKVLTIKPHGMVVKMGKQIRGLVPTMHLADILIKNPEKKYHVGDEVKCRVLLCDPKAKKLMMTLKKTLVESKLPAITCYDDAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPRHELSAEYVPDPESVFYTGQVVKVVVLNCEPSKERMLLSFRLLSDPKQEGEGQSQKKKKAVSAGQLVDVKVLEKTKDGLKVAVLPHNIPGFLPTAHLSDHVTNGPLLYHWLQTGDTLHRVLCLSVSEERVLLCRKPALVSAVEGGQNPKSFSEIHPGMLLIGFVKNIKDYGVFVQFPSGLSGLAPKAILSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSLRLSDCTLGDLATTSLLLLSQCLEERQGVRSLMSNRDSVLIQTLAEMTPGMALDLEVQEVLEDGSVLFSEGPVPGLVLRASKYHRAGQELEPGQKKKAVILNVDMLKLEVHVSLCHDLVNRKAKKLKKGSDLQAIVQHLEESFAVASLVETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLQTTEPGVTGLLLAIEGPAAKRTMRQTRKDSETVDEDEEVDPALVVGTVKKHTLSIGDVVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKKVTARVIGGRDMKTFKFLPISHPRFIRTIPELSVRPSELKEDGHTTLNTHSVSPLEKIKQYQPGQTVTCFLKKYNMVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFQIGQALKATVVGPAESSKAFLCLSLIGPHKLKKGEVAMGRVVKVTPKEGLTVSFPFGRVGRVSMFHVSDSYSETHLEDFVPQQVVRCYVLSAATPVLTLSLRSSRTNPETKSKITDPEINSIEDLEEGQLLRGFVKSVQPSGVLVGLGPSVTGLARHPHVSQHNQSKNAPYDRHLPEGKLLTAKVLRLNHQESLVELSLLPDATGKQDVLSAPLGQPPPKQEGRETEAVERNHEGKAKEKKKQKQKEKRTGKGQEGAQPPSKDKKEPQKPQAKKLGKRPHPESSSEQEIGNKKQKKAALSEEDDSGVEVYYREGEEAEEMSMLPKEKLTRPAEAPRLQLSSGFVWDVGLDTLTPALPPHGDSSDSEEDEKPEQATQKKKSKKERELEKQKAEKELSRIEEALMDPGRQPESAEDFDRLVLSSPSSSLLWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRFRQEKAVWVKYGAFLLRRGKAEASHRVMQRALECLPKKEHVDVIAKFAQLEFQLGDAERARAIFESTLSIYPKRTDVWSVYIDMIIKHGSQKEARAIFERVIHLSLAPKRMKFFFKRYLDYEKQHGSEKDVQAVKAKALEYVEAKSSMMDD", "length": 1874, "header": "tr|G5E5C4-1|G5E5C4_BOVIN Isoform 1 of Protein RRP5 homolog OS=Bos taurus OX=9913 GN=PDCD11 PE=4 SV=2 CANONICAL=G5E5C4-1" }, "isoforms": [ { "isoform_ac": "G5E5C4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5C4/entry", "sequence": { "sequence": "MAAMEESFPRGGTRKTHKSEKAFQQSVEQDNLFDISTEEESTKRKKIQKGPAKTKKLKVETRQSSKFVREKFEILNVESLCEGMRILGCVKEVNELELAISLPNGLQGYVQVTEICDAYTEKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLDTTKGSKKNVMLSLNPKNVNRVLSAETLKPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNKGAKLKVGQYLNCLIEEVKGSRGVVTLSIGHSEVSAAIATEEQSWTLNSLLPGLVVKAQVQKVTPLGLTLKFLSFFSGLVDFMHLDPKKAGTYFSNQQVRACVLCVHPRTRAVRLSLRPVFLQPGRPLTRLLCQQLGAVLDDVPVQGFFGSAGATFKLKDGTLAYARRNHLSNSKKTFKPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYHDIKPGALVKGKVLTIKPHGMVVKMGKQIRGLVPTMHLADILIKNPEKKYHVGDEVKCRVLLCDPKAKKLMMTLKKTLVESKLPAITCYDDAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPRHELSAEYVPDPESVFYTGQVVKVVVLNCEPSKERMLLSFRLLSDPKQEGEGQSQKKKKAVSAGQLVDVKVLEKTKDGLKVAVLPHNIPGFLPTAHLSDHVTNGPLLYHWLQTGDTLHRVLCLSVSEERVLLCRKPALVSAVEGGQNPKSFSEIHPGMLLIGFVKNIKDYGVFVQFPSGLSGLAPKAILSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSLRLSDCTLGDLATTSLLLLSQCLEERQGVRSLMSNRDSVLIQTLAEMTPGMALDLEVQEVLEDGSVLFSEGPVPGLVLRASKYHRAGQELEPGQKKKAVILNVDMLKLEVHVSLCHDLVNRKAKKLKKGSDLQAIVQHLEESFAVASLVETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLQTTEPGVTGLLLAIEGPAAKRTMRQTRKDSETVDEDEEVDPALVVGTVKKHTLSIGDVVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKKVTARVIGGRDMKTFKFLPISHPRFIRTIPELSVRPSELKEDGHTTLNTHSVSPLEKIKQYQPGQTVTCFLKKYNMVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFQIGQALKATVVGPAESSKAFLCLSLIGPHKLKKGEVAMGRVVKVTPKEGLTVSFPFGRVGRVSMFHVSDSYSETHLEDFVPQQVVRCYVLSAATPVLTLSLRSSRTNPETKSKITDPEINSIEDLEEGQLLRGFVKSVQPSGVLVGLGPSVTGLARHPHVSQHNQSKNAPYDRHLPEGKLLTAKVLRLNHQESLVELSLLPDATGKQDVLSAPLGQPPPKQEGRETEAVERNHEGKAKEKKKQKQKEKRTGKGQEGAQPPSKDKKEPQKPQAKKLGKRPHPESSSEQEIGNKKQKKAALSEEDDSGVEVYYREGEEAEEMSMLPKEKLTRPAEAPRLQLSSGFVWDVGLDTLTPALPPHGDSSDSEEDEKPEQATQKKKSKKERELEKQKAEKELSRIEEALMDPGRQPESAEDFDRLVLSSPSSSLLWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRFRQEKAVWVKYGAFLLRRGKAEASHRVMQRALECLPKKEHVDVIAKFAQLEFQLGDAERARAIFESTLSIYPKRTDVWSVYIDMIIKHGSQKEARAIFERVIHLSLAPKRMKFFFKRYLDYEKQHGSEKDVQAVKAKALEYVEAKSSMMDD", "length": 1874, "header": "tr|G5E5C4-1|G5E5C4_BOVIN Isoform 1 of Protein RRP5 homolog OS=Bos taurus OX=9913 GN=PDCD11 PE=4 SV=2 CANONICAL=G5E5C4-1" }, "locus": { "chromosome": "26", "start_pos": 24028737, "end_pos": 23989791, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012818.8", "url": "https://www.ensembl.org/id/ENSBTAT00000012818.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012818.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012818.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZNI3-1", "protein_name": "Protein RRP5 homolog", "gene_name": "Pdcd11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANLEESFPRGGTRKPHKSEKSSQPVVEQDNLFDISTEEGSVKRKKSQKGPAKTKKLKIEKRKSNKSMKEKFEILSLESLCEGMRILGCVKEVNELELVVSLPNGLQGFVQVTEICDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLSVNPKRVNKVLSAEALRPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLSLQKAQEYIRQKNKGAKFKVGQYLTCVVEELKSNGGVVSLSVEHSQVSSAFATEEQSWNLNNLLPGLVVRAQVQKVTQFGLQLNFLTFFTGLVDFMHLEPKKMGSYSSKQTVKACILCVHPRTRVVRLSLRPIFLHPGRPLTRISYQQLGTVLDDASVEGFFEKAGAIFRLRDGVLAYARLSHLSDSKKAFSAEAFKLGSTHRCRIIDYSQMDELALLSLRKSIIAAPFLRYQDIKTGTIVKGKVLALKPFGMLVKVGEQMRGLVPSMHLADIMMKNPEKKFNTGDEVKCRVLLCDPEAKKLIMTLKKTLVTSKLPAITCYEDAKPGLQTHGVIIRVKDYGCLVKFYNDVQGLVPKHELSAQHIPDPERVFYTGQVVKVAVLNCEPSKERMLLSFKLLSGSEPKDESVKNSKKKGSTVNTGQQLVDVKVLEKTKNGLEVAILPHNIPAFLPTPHLSDHVANGPLLHHWLQTGDTLHRVLCLSQSEKHILLCRKPALVSTVEGGQDPKSLSEIQPGMLLIGFVKSIKDYGVFVQFPSGLSGLSPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLLCQCLEELQGIRSLMSNQDSVLIQTLADMTPGMVLDAMVQEVLENGSVVFGGGPVPDLILRASRYHRAGQELEPGQKKKVVVLHVDALKLEVHVSLHQDLVNRKARKLRKNSRHQGIVQHLEESFAVASLVETGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVTGLILAVEGPASKRIRMPAQRDSETVDDKGEEEEEEEEEDLTVRSKKSHSLAIGDKVTGTIKSVKATHAVVTLDDGFIGCIHVSRILDDVPEGVSPTTTLKAGKKVTARVIGGRDVKTSKFLPISHPRFVLTILELSVRPSELKGDYRALNTHSVSPMEKIRQYQAGQTVTCFLKKYNVMKKWLEVDIEPDIRGRIPLLLTSLSFKVLKHPDKKFQIGQAIKATVVGPDIPRAFLCLSLIGPYKLEEGDVAMGRVLKVLPNKGLTVSFPFGRIGKVSVFHLSDSYSEEPLTDFCPQKIVRCYILSTAHRMLALSLRSSRTNKETKSKIEDPEVNSIEDIQAGQLLRGYVKSILPSSVVIGLGPSVMGLVKHSHVSQCVSREKELYDKCLPEGKLVTARVLCVNPKKNLIELSLLPSDTGKPDVFSASPEPPLPKQEGREGGTEKGLKGESKRSQRRREKNQKMREESGLYSQEKKEPRKSQRGGQSKRERQESESEQELVNKRPKKSGAPEDDDSGVEVYYREGEDEVEEPKVPPGGKQSKPTEVPRLQLSKGFIWDVGLDSLTPALPLRGESSDSEEDEQPHQAKKKKGKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLAKVFERAVQYNEPLKVFLHLADIYTKSEKFKEAGELYNRMLKRFRQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPTKEHVDVIVKFAQLEFQLGDVERAKAIFENTLTTYPKRTDVWSVYIDMTIKHGSQKEVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSALEDQ", "length": 1877 }, "evidence": [ { "id": "G5E5C4", "url": "https://omabrowser.org/oma/group/G5E5C4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4J8K6-1", "protein_name": "rRNA biogenesis protein RRP5", "gene_name": "RRP5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVVPQKKFANGKRNDSTKSFKPMKKPFKKTKDDVAARSEAMALQLEDVPDFPRGGGTSLSKKEREKLYEEVDAEFDADERVSKKSKGGKSKKRIPSDLDDLGLLFGGGLHGKRPRYANKITTKNISPGMKLLGVVTEVNQKDIVISLPGGLRGLVRASEVSDFTDRGIEDDENELLGDIFSVGQLVPCIVLELDDDKKEAGKRKIWLSLRLSLLHKGFSFDSFQLGMVFSANVKSIEDHGSILHFGLPSITGFIEISDDGNQESGMKTGQLIQGVVTKIDRDRKIVHLSSDPDSVAKCLTKDLSGMSFDLLIPGMMVNARVQSVLENGILFDFLTYFNGTVDLFHLKNPLSNKSWKDEYNQNKTVNARILFIDPSSRAVGLTLSPHVVCNKAPPLHVFSGDIFDEAKVVRIDKSGLLLELPSKPTPTPAYVSTYDAAGDEVTKLEKKFKEGNHIRVRVLGLKQMEGLAVGTLKESAFEGPVFTHSDVKPGMVTKAKVISVDTFGAIVQFSGGLKAMCPLRHMSEFEVTKPRKKFKVGAELVFRVLGCKSKRITVTYKKTLVKSKLPILSSYTDATEGLVTHGWITKIEKHGCFVRFYNGVQGFVPRFELGLEPGSDPDSVFHVGEVVKCRVTSAVHGTQRITLSFMIKPSSVSEDDSIKLGSIVSGIIDTITSQAVIVRVKSKSVVKGTISAEHLADHHEQAKLIMSLLRPGYELDKLLVLDIEGNNMALSSKYSLIKLAEELPSDFNQLQPNSVVHGYVCNLIENGCFVRFLGRLTGFAPRSKAIDDPKADVSESFFVGQSVRANIVDVNQEKSRITLSLKQSSCASVDASFVQEYFLMDEKISDLQSSDITKSDCSWVEKFSIGSLIKGTIQEQNDLGVVVNFDNINNVLGFIPQHHMGGATLVPGSVVNAVVLDISRAERLVDLSLRPELLNNLTKEVSNSSKKKRKRGISKELEVHQRVSAVVEIVKEQHLVLSIPEHGYTIGYASVSDYNTQKLPVKQFSTGQSVVASVKAVQNPLTSGRLLLLLDSVSGTSETSRSKRAKKKSSCEVGSVVHAEITEIKPFELRVNFGNSFRGRIHITEVNDASTSDEPFAKFRVGQSISARVVAKPCHTDIKKTQLWELSVKPAMLKDSSEFNDTQESEQLEFAAGQCVIGYVYKVDKEWVWLAVSRNVTARIFILDTSCKAHELEEFERRFPIGKAVSGYVLTYNKEKKTLRLVQRPLLFIHKSIANGGGSKTDKPDSSIPGDDDTLFIHEGDILGGRISKILPGVGGLRVQLGPYVFGRVHFTEINDSWVPDPLDGFREGQFVKCKVLEISSSSKGTWQIELSLRTSLDGMSSADHLSEDLKNNDNVCKRFERIEDLSPDMGVQGYVKNTMSKGCFIILSRTVEAKVRLSNLCDTFVKEPEKEFPVGKLVTGRVLNVEPLSKRIEVTLKTVNAGGRPKSESYDLKKLHVGDMISGRIRRVEPFGLFIDIDQTGMVGLCHISQLSDDRMENVQARYKAGESVRAKILKLDEEKKRISLGMKSSYLMNGDDDKAQPLSEDNTSMECDPINDPKSEVLAAVDDFGFQETSGGTSLVLAQVESRASIPPLEVDLDDIEETDFDSSQNQEKLLGANKDEKSKRREKQKDKEEREKKIQAAEGRLLEHHAPENADEFEKLVRSSPNSSFVWIKYMAFMLSLADIEKARSIAERALRTINIREEEEKLNIWVAYFNLENEHGNPPEESVKKVFERARQYCDPKKVYLALLGVYERTEQYKLADKLLDEMIKKFKQSCKIWLRKIQSSLKQNEEAIQSVVNRALLCLPRHKHIKFISQTAILEFKCGVADRGRSLFEGVLREYPKRTDLWSVYLDQEIRLGEDDVIRSLFERAISLSLPPKKMKFLFKKFLEYEKSVGDEERVEYVKQRAMEYANSTLA", "length": 1920 }, "evidence": [ { "id": "G5E5C4", "url": "https://omabrowser.org/oma/group/G5E5C4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q05022-1", "protein_name": "rRNA biogenesis protein RRP5", "gene_name": "RRP5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVASTKRKRDEDFPLSREDSTKQPSTSSLVRNTEEVSFPRGGASALTPLELKQVANEAASDVLFGNESVKASEPASRPLKKKKTTKKSTSKDSEASSANSDEARAGLIEHVNFKTLKNGSSLLGQISAITKQDLCITFTDGISGYVNLTHISEEFTSILEDLDEDMDSDTDAADEKKSKVEDAEYESSDDEDEKLDKSNELPNLRRYFHIGQWLRCSVIKNTSLEPSTKKSKKKRIELTIEPSSVNIYADEDLVKSTSIQCAVKSIEDHGATLDVGLPGFTGFIAKKDFGNFEKLLPGAVFLGNITKKSDRSIVVNTDFSDKKNKITQISSIDAIIPGQIVDLLCESITKNGIAGKVFGLVSGVVNVSHLRTFSEEDLKHKFVIGSSIRCRIIACLENKSGDKVLILSNLPHILKLEDALRSTEGLDAFPIGYTFESCSIKGRDSEYLYLALDDDRLGKVHSSRVGEIENSENLSSRVLGYSPVDDIYQLSTDPKYLKLKYLRTNDIPIGELLPSCEITSVSSSGIELKIFNGQFKASVPPLHISDTRLVYPERKFKIGSKVKGRVISVNSRGNVHVTLKKSLVNIEDNELPLVSTYENAKNIKEKNEKTLATIQVFKPNGCIISFFGGLSGFLPNSEISEVFVKRPEEHLRLGQTVIVKLLDVDADRRRIIATCKVSNEQAAQQKDTIENIVPGRTIITVHVIEKTKDSVIVEIPDVGLRGVIYVGHLSDSRIEQNRAQLKKLRIGTELTGLVIDKDTRTRVFNMSLKSSLIKDAKKETLPLTYDDVKDLNKDVPMHAYIKSISDKGLFVAFNGKFIGLVLPSYAVDSRDIDISKAFYINQSVTVYLLRTDDKNQKFLLSLKAPKVKEEKKKVESNIEDPVDSSIKSWDDLSIGSIVKAKIKSVKKNQLNVILAANLHGRVDIAEVFDTYEEITDKKQPLSNYKKDDVIKVKIIGNHDVKSHKFLPITHKISKASVLELSMKPSELKSKEVHTKSLEEINIGQELTGFVNNSSGNHLWLTISPVLKARISLLDLADNDSNFSENIESVFPLGSALQVKVASIDREHGFVNAIGKSHVDINMSTIKVGDELPGRVLKIAEKYVLLDLGNKVTGISFITDALNDFSLTLKEAFEDKINNVIPTTVLSVDEQNKKIELSLRPATAKTRSIKSHEDLKQGEIVDGIVKNVNDKGIFVYLSRKVEAFVPVSKLSDSYLKEWKKFYKPMQYVLGKVVTCDEDSRISLTLRESEINGDLKVLKTYSDIKAGDVFEGTIKSVTDFGVFVKLDNTVNVTGLAHITEIADKKPEDLSALFGVGDRVKAIVLKTNPEKKQISLSLKASHFSKEAELASTTTTTTTVDQLEKEDEDEVMADAGFNDSDSESDIGDQNTEVADRKPETSSDGLSLSAGFDWTASILDQAQEEEESDQDQEDFTENKKHKHKRRKENVVQDKTIDINTRAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKGDPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAKDKKKVEDLFERIITKKITRKQAKFFFNKWLQFEESEGDEKTIEYVKAKATEYVASHESQKADE", "length": 1729 }, "evidence": [ { "id": "G5E5C4", "url": "https://omabrowser.org/oma/group/G5E5C4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14690-1", "protein_name": "Protein RRP5 homolog", "gene_name": "PDCD11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANLEESFPRGGTRKIHKPEKAFQQSVEQDNLFDISTEEGSTKRKKSQKGPAKTKKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGFVQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPERVFYTGQVVKVVVLNCEPSKERMLLSFKLSSDPEPKKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVLCLSQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSLRLSDCGLGDLAITSLLLLNQCLEELQGVRSLMSNRDSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDLVLKASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRKARKLRKGSEHQAIVQHLEKSFAIASLVETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVTGLLLAVEGPAAKRTMRPTQKDSETVDEDEEVDPALTVGTIKKHTLSIGDMVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRDMKTFKYLPISHPRFVRTIPELSVRPSELEDGHTALNTHSVSPMEKIKQYQAGQTVTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFRVGQALRATVVGPDSSKTLLCLSLTGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSYSETPLEDFVPQKVVRCYILSTADNVLTLSLRSSRTNPETKSKVEDPEINSIQDIKEGQLLRGYVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSVLED", "length": 1871 }, "evidence": [ { "id": "G5E5C4", "url": "https://omabrowser.org/oma/group/G5E5C4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NS46-1", "protein_name": "Protein RRP5 homolog", "gene_name": "Pdcd11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANLEESFPRGGTRKLHKSEKSSQQVVEQDNLFDVSTEEGPIKRKKSQKGPAKTKKLKIEKRKSIKSIKEKFEILSLESLCEGMRILGCVKEVSELELVVSLPNGLQGFVQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLSVNPKRVNKVLSADALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNKGAKFKVGQYLTCVVEEVKSNGGVVSLSVEHSEVSSAFATEEQSWNLNNLLPGLLVKAQVQKVTQFGLQLNFLTFFKGLVDFMHLEPKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIFLHPGRPLTRISYQQLGAVLDDVPVQGFFKNAGAIFRLKDGVLAYARVSHLSDSKKAFNAEAFKPGSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKIGTVVKGTVLAIKPFGILVKVGEQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLKKTLVTSKLSLITCYEGAKPGLQTHGVIIRVKDYGCIVKFYNDVQGLVPKHELSTQHIPDPETVFYTGQVVKVAVLSCEPSKERMLLSFRLLSDSRPKDPGVESSQKKTGAVRIGQLVDVKVLEKTKTGLEVAILPHNTPAFLPTPHLSDHAANGPLLHHWLQTGDTLHRVLCLSQSERHILLCRKPALVSTVEGGQDPKSLSEIQPGMLLIGFVKCIKEYGVFVQFPSGLSGLSPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLLCQCLEELQGIRSLMSNQDSVLIQTLADMTPGMVLDAVVHEVLEDGSVVFSSDPVPDLVLRASRYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLVNRKTRKLRKSSRHQGIVQHLEESFAVASLVETGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVTGLILAVEGPASKRTRMPVQRDSETVDDKGEEKEEEEEEEEKEEENLTVKSKKRHSLAIGDKVTGTIKAVKATHVVVTLADGFVGCIHASRILDDVPVGTSPTTTLKAGKKVTARVIGGRDVKTSKFLPISHPRFVLTILELSVRPSELKGSYSALNTHSESPVEKIRQYQAGQTVTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDKKFQVGQAIEATVVDPDVPRAFLCLSLIGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKIGKVSMFHLSDSYSEAPLEDFCPQKIVRCYILSTAHRVLALSLRSSRTNRETKNRIEDPEINSIEDVKEGQLLRGYVKCVLPSSVIIGLGPSVLGLAKYSHVSECVPPEKELYNGCLPEGKLVTAKVLRVNPMKNLIELSLLPSDTGRPDVFSPAPEPKQEERSGGAEEGQKRKEKNQKRREEKEEPQKSQRGGRGKRERQESESEQELVNKRPKKSGAAEEDDSGVEVYYREGEDEVGEPKLPPRGKQTKSTEVPRLHLSSGFLWDVGLDSLTPALPLREESSDSEDEQPHQAKKKKGKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKYKEAGELYNRMLKRFRQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAKEHVDVIVKFAQLEFQLGDVERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQTAVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSALED", "length": 1862 }, "evidence": [ { "id": "G5E5C4", "url": "https://omabrowser.org/oma/group/G5E5C4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G5E5C4", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" } ], "pmid": "" }, { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "G5E5C4", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "G5E5C4", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E5C4", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "G5E5C4", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "G5E5C4", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1360, "end_pos": 1362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C4" }, { "id": "PS50126", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50126" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S1 motif", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 171, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1360, "end_pos": 1362 }, { "start_pos": 958, "end_pos": 960 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5C8-1", "uniprot_ac": "G5E5C8", "uniprot_id": "G5E5C8_BOVIN", "mass": { "chemical_mass": 37681.0, "monoisotopic_mass": 37681.0 }, "refseq": {}, "gene_names": [ { "name": "TALDO1", "type": "recommended", "evidence": [ { "id": "G5E5C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ] } ], "protein_names": [ { "name": "Transaldolase", "type": "recommended", "evidence": [ { "id": "G5E5C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C8/entry#names_and_taxonomy" } ] }, { "name": "2.2.1.2", "type": "synonym", "evidence": [ { "id": "G5E5C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.", "evidence": [ { "database": "UniProtKB", "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8#function" }, { "database": "UniProtKB", "id": "RU000501", "url": "https://www.uniprot.org/uniprotkb/RU000501#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TALDO1", "url": "https://www.uniprot.org/uniprotkb/G5E5C8", "locus": { "chromosome": "29", "start_pos": 50591286, "end_pos": 50598649, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010336", "url": "https://www.ensembl.org/id/ENSBTAG00000010336" } ] } } ], "crossref": [ { "id": "G5E5C8", "url": "https://alphafold.ebi.ac.uk/entry/G5E5C8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010336", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010336", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00957", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00957", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513453", "url": "https://www.ncbi.nlm.nih.gov/gene/513453", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513453", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513453", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THAEFLW", "url": "https://omabrowser.org/oma/group/THAEFLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5C8", "url": "https://www.orthodb.org/?gene=G5E5C8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10683:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10683:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-163754", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163754", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-71336", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71336", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001030360", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030360", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17053", "url": "https://www.rhea-db.org/rhea/17053", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5C8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSPVKRQRMENALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPTYQELVEEAIAYGRKLGGSQEEQITNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKERILIKLSSTWEGIQAGKELEEHHGIRCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPQLLGELLKDHSKLTPVLSAKAAQASDLEKIQLDEKAFRWLHNEDRMAVEKLSDGIRRFAADAVKLERMLRERMFSAENGK", "length": 337, "header": "tr|G5E5C8-1|G5E5C8_BOVIN Isoform 1 of Transaldolase OS=Bos taurus OX=9913 GN=TALDO1 PE=1 SV=1 CANONICAL=G5E5C8-1" }, "isoforms": [ { "isoform_ac": "G5E5C8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5C8/entry", "sequence": { "sequence": "MSGSPVKRQRMENALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPTYQELVEEAIAYGRKLGGSQEEQITNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKERILIKLSSTWEGIQAGKELEEHHGIRCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPQLLGELLKDHSKLTPVLSAKAAQASDLEKIQLDEKAFRWLHNEDRMAVEKLSDGIRRFAADAVKLERMLRERMFSAENGK", "length": 337, "header": "tr|G5E5C8-1|G5E5C8_BOVIN Isoform 1 of Transaldolase OS=Bos taurus OX=9913 GN=TALDO1 PE=1 SV=1 CANONICAL=G5E5C8-1" }, "locus": { "chromosome": "29", "start_pos": 50598593, "end_pos": 50591456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013650.5", "url": "https://www.ensembl.org/id/ENSBTAT00000013650.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013650.3", "url": "https://www.ensembl.org/id/ENSBTAP00000013650.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:513453", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513453", "resource": "KEGG Pathway" }, { "id": "R-BTA-163754", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163754", "resource": "Reactome", "description": "Insulin effects increased synthesis of Xylulose-5-Phosphate" }, { "id": "R-BTA-71336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71336", "resource": "Reactome", "description": "Pentose phosphate pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PC23-1", "protein_name": "Transaldolase", "gene_name": "TALDO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVSPVKRQKMESALEQLKHHTTVVADTGDFNAIDEYKPLDATTNPSLILAAAQMPAYQKLVDDAVAYGKKLGGSEDEQIQNACDKLFVLFGAEILKRIPGRVSTEVDARLSFDKEGMIQRARRLIDLYKEVGIGKDRILIKLSSTWEGIQAGKVLEAEYGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANGDKKTYEPSEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALTGCDYLTISPKLLAELSKEHVKLTPTLSVKEAQACDLEKIHLDEKAFRWHHNEDQMAVEKLSDGIRKFAADAIKLERMLKERMFGTENGK", "length": 337 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I3G8-1", "protein_name": "Transaldolase", "gene_name": "Taldo1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARAKRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNTKLAPVLSIKAAQTSDLEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK", "length": 337 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P37837-1", "protein_name": "Transaldolase", "gene_name": "TALDO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSPVKRQRMESALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIHLDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK", "length": 337 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q29593-1", "protein_name": "Transaldolase", "gene_name": "TALDO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEALAYGKRLGGSQEEQVTNAVDKLFVLFGAEILKKIPGRVSTEVDARLSFDRDAMVARARRLIELYKEAGVSKDRVLIKLASTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDQKSYEPLEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPQLLGELLKDTSKLVPMLSAKAAQASPLEKVHLDEKAFRWLHNEDRMAVEKLSDGIRKFAADAVKLERMLTERMFSTENGK", "length": 337 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54UP4-1", "protein_name": "Probable transaldolase", "gene_name": "tal", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNALEELKKYTTVVADTADFDVLSKYGSQDSTTNPSLVFQAASDPKYKSLIDDAIKYVNAKSGLSEKEKLSLAIDKLFVNFGVEILKIVPGRVSTEVDARLSYDIDANVKKGRELIALYKEAGIDKERVLIKLASTWEGIEAAKILEKEGIHCNLTLLFSLIQAAACAEAQVTLISPFVGRITDFYKSKQGVAGFEASKDPGVISVQQIYSYFKKHGYKTSVMGASFRNKEQTIELAGCDLLTISPNLLEELKNADASLVTKKLDSTKLPSDIPNKLDVSHSNFLWELNDNEMAYFKTGEGIRKFAEDLVKLENQIKKLL", "length": 321 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q93092-1", "protein_name": "Transaldolase", "gene_name": "Taldo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGVGKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNSKLAPALSVKAAQTSDSEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK", "length": 337 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EQS0-1", "protein_name": "Transaldolase", "gene_name": "Taldo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRIIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDSSKLAPTLSVKAAQTSDLEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK", "length": 337 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9FWX0-1", "protein_name": "transaldolase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPLSLQSPPCATLSASIRKGRWKTLAAGFSVTPLPAVNFSLRRSIPRILASASSSSSPASSSLEAGENNELNAVSAFSEIVPDTVVFDDFERFPPTAATVSSALLLGICGLPDTIFRNAVDMALADSSCAGLETTESRLSCFFNKAIVNVGGDLVKLVPGRVSTEVDARLAYDTNGIIRKVHDLLRLYNEIDVPHDRLLFKIPATWQGIEAARLLESEGIQTHMTFVYSFAQAAAASQAGASVIQIFVGRLRDWARNHSGDTEIESAIKSGEDPGLALVKRSYNYIHKYGYKSKLMAAAVRNKQDLFSLLGVDYVIAPLKVLQSLKDSPAIPDDEKYSFVRKLTPETATHYHFTNKELVKWDQLSLASSMGPASVELLSAGVEGYANQAKRVEELFGKIWPPPNV", "length": 405 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W1G0-1", "protein_name": "Probable transaldolase", "gene_name": "Taldo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGSDRTLKKQKMSVLQELKKITTIVADTGDFEAINIYKPTDATTNPSLILSASSMERYQPLVQKAVEYAKGKKGSVSEQVAEAMDYLCVLFGTEILKVVPGRVSTEIDARLSFDTKKSVEKALKLIALYKSLGVDKERILIKLASTWEGIKAAEILENEHGVHCNLTLLFSFAQAVACAEAGVTLISPFVGRILDWYVANTDTKKFEALKDPGVISVTNIYNYYKKFGYKTLVMGASFRNVGEIKALAGCDLLTISPALLKELENETESVVTYLSVSNAKLQDIEKITVDESRFRWLLNEDAMATDKLSEGIRKFAVDTVKLENLIKTYLK", "length": 331 }, "evidence": [ { "id": "G5E5C8", "url": "https://omabrowser.org/oma/group/G5E5C8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "pentose-phosphate shunt, non-oxidative branch", "id": "GO:0009052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009052", "evidence": [ { "database": "UniProtKB", "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transaldolase activity", "id": "GO:0004801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004801", "evidence": [ { "database": "UniProtKB", "id": "G5E5C8", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17053", "name": "", "equation": "D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5C8-1", "Q2TBL6-1" ], "evidence": [ { "id": "17053", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17053" } ] }, { "id": "R-BTA-163764", "name": "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5C8-1" ], "evidence": [ { "id": "R-BTA-163764", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163764" } ] }, { "id": "R-BTA-71334", "name": "sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29882" ], "output_participant_list": [ "R-ALL-29878" ], "enzyme_list": [ "G5E5C8-1" ], "evidence": [ { "id": "R-BTA-71334", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71334" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29878", "participant_name": "E4P [cytosol]", "crossref": [ { "id": "8143600", "database": "PubChem Substance", "url": "" }, { "id": "16897", "database": "ChEBI", "url": "" }, { "id": "ZINC000032786787", "database": "ZINC", "url": "" }, { "id": "C00279", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-29882", "participant_name": "SH7P [cytosol]", "crossref": [ { "id": "57483", "database": "ChEBI", "url": "" }, { "id": "ZINC000005132038", "database": "ZINC", "url": "" }, { "id": "C00281", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "G5E5C8", "gene_name": "TALDO1", "activity": [ { "ec_number": "2.2.1.2", "activity": "D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate.", "evidence": [ { "id": "G5E5C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ] }, { "ec_number": "2.2.1.2", "activity": "", "evidence": [ { "id": "G5E5C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5C8" } ] } ] }, { "uniprot_ac": "Q2TBL6", "gene_name": "TALDO1", "activity": [ { "ec_number": "2.2.1.2", "activity": "D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate.", "evidence": [ { "id": "Q2TBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL6" } ] }, { "ec_number": "2.2.1.2", "activity": "", "evidence": [ { "id": "Q2TBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5C8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 337, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5C8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5C8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.2.1.2", "ec_name": "D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate.", "evidence": [ { "id": "2.2.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.2.1.2" }, { "id": "2.2.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.2.1.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RJX5-1", "protein_name": "NFKB activating protein", "gene_name": "NKAP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPVSGSRSPEWEASGSGGKRRSSSKSPKPCSKSSRSPRGRRSRSHSCSRSGDRNGLSHQSSGPSQGSRNQSYRSRSRSRSRERPSAPRGAPFASASSAYYGGYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKRKKKSGHSKERSKKRRKKKSSKRKHKKYSDDSDSDSDSDTDSSDEDTKRRAKKSKKKEKKKKRRSKKYKKKKSKKSRKDSSDSSSKESQEELLENPWKDRSKPEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKEDK", "length": 417 }, "evidence": [ { "id": "G5E5D9", "url": "https://omabrowser.org/oma/group/G5E5D9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, 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"monoisotopic_mass": 34835.0 }, "refseq": { "ac": "NP_001377391", "name": "olfactory receptor family 4 subfamily C member 180", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377391" }, "gene_names": [ { "name": "OR4C180", "type": "recommended", "evidence": [ { "id": "G5E5E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5E3" } ] }, { "name": "OR4C16", "type": "synonym", "evidence": [ { "id": "NP_001377391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377391" } ] }, { "name": "OR4C180", "type": "synonym", "evidence": [ { "id": "NP_001377391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377391" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E5E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5E3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily C member 180", "type": "synonym", "evidence": [ { "id": "NP_001377391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377391" } ] }, { "name": "olfactory receptor, family 4, subfamily C, member 16", "type": "synonym", "evidence": [ { "id": "NP_001377391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377391" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377391" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E5E3", "url": "https://www.uniprot.org/uniprotkb/G5E5E3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5E3", "url": "https://www.uniprot.org/uniprotkb/G5E5E3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4C180", "url": "https://www.uniprot.org/uniprotkb/G5E5E3", "locus": { "chromosome": "15", "start_pos": 968982, "end_pos": 968050, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000067346", "url": "https://www.ensembl.org/id/ENSBTAG00000067346" } ] } } ], "crossref": [ { "id": "G5E5E3", "url": "https://alphafold.ebi.ac.uk/entry/G5E5E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "786506", "url": "https://www.ncbi.nlm.nih.gov/gene/786506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:786506", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786506", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITLMSHR", "url": "https://omabrowser.org/oma/group/ITLMSHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5E3", "url": "https://www.orthodb.org/?gene=G5E5E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5E3", "url": "https://www.uniprot.org/uniprotkb/G5E5E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5E3-1", "url": "https://www.uniprot.org/uniprotkb/G5E5E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLNNNVTEFILLGLSQDPVRKKIVFVTFLFLYLGMLLGNFLIISTIKTSRTLGSPMYFFLFHLSLSDTFLSTSIAPRVIVDALREKSTISFNECMIQVFASHFFGCLEIFILILMAVDRYVAICKPLRYITLMSHRVCGVLVTVAWVGSCVHSSAQILLALSLPFCGRNVIDHYFCDLQPLLKLACTDTYATNLLLVSNSGAICTVSFVMLMFSYAIILHSLRNHSAEGRKKALSTCISHIIVVILFFGPCIFIYTRPATTFPMDKMIAVFYTVGTPLINPLTYSLRNTEVKNAMRMLWGKKLITGDKI", "length": 310, "header": "tr|G5E5E3-1|G5E5E3_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR4C180 PE=3 SV=2 CANONICAL=G5E5E3-1" }, "isoforms": [ { "isoform_ac": "G5E5E3-1", "url": "https://www.uniprot.org/uniprotkb/G5E5E3/entry", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376766" }, "gene_names": [ { "name": "OR4C160", "type": "recommended", "evidence": [ { "id": "G5E5J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5J4" } ] }, { "name": "OR4C160", "type": "synonym", "evidence": [ { "id": "NP_001376766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376766" } ] }, { "name": "OR4C6", "type": "synonym", "evidence": [ { "id": "NP_001376766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376766" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 4 subfamily C member 160", "type": "synonym", "evidence": [ { "id": "G5E5J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5J4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily C member 160", "type": "synonym", "evidence": [ { "id": "NP_001376766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376766" } ] }, { "name": "olfactory receptor, family 4, subfamily C, member 6", "type": "synonym", "evidence": [ { "id": "NP_001376766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376766" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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triggers the perception of a smell. 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"sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5M8-1", "uniprot_ac": "G5E5M8", "uniprot_id": "G5E5M8_BOVIN", "mass": { "chemical_mass": 113711.0, "monoisotopic_mass": 113711.0 }, "refseq": {}, "gene_names": [ { "name": "LOC532207", "type": "recommended", "evidence": [ { "id": "G5E5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ] } ], "protein_names": [ { "name": "Alpha-mannosidase", "type": "recommended", "evidence": [ { "id": "G5E5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5M8/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.-", "type": "synonym", "evidence": [ { "id": "G5E5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5M8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Specifically cleaves terminal alpha 1,6-linked mannose residues on Man3GlcNAc and Man2GlcNAc core oligosaccharides generated by N-glycan degradation pathways, having little activity, if any, on larger mannose oligosaccharides. Does not cleave terminal alpha 1,6-linked mannose on Man3GlcNAc2, and is also unable to hydrolyze terminal alpha 1,3-mannose linkages.", "evidence": [ { "database": "UniProtKB", "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8#function" }, { "database": "UniProtKB", "id": "ARBA00094269", "url": "https://www.uniprot.org/uniprotkb/ARBA00094269#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC532207", "url": "https://www.uniprot.org/uniprotkb/G5E5M8", "locus": {} } ], "crossref": [ { "id": "G5E5M8", "url": "https://alphafold.ebi.ac.uk/entry/G5E5M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019584", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019584", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VIRRINW", "url": "https://omabrowser.org/oma/group/VIRRINW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11607:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11607:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01074", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01074", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07748", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07748", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "84971", "url": "https://www.rhea-db.org/rhea/84971", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84987", "url": "https://www.rhea-db.org/rhea/84987", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P3K0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3K0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5M8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRGWLPLLLQLGLMWPPWAQPEPQLRVFVVPHSHMDVGWLHTVQENMQAYVTNVYNSVVEALTLEKKRRFIAVEQEYFRLWWDGVASHWQKRKVHQLVAKGRLEFVLGGQVMHDEAVTHIDDQILQLTEGHGFLYETFGVRPQISWQVDPFGASSTTPTLFALAGFNAHVISRIDYDLKEAMQDNRQLQFVWRGSRSLSAEQEIFTHVLDQFSYSKVPRYEGFNWDGEAIFPGPSLDGKYPSMEIPVTEDSIPDFTHLLGKRVLHKASWFQTAHILWPWGCDRQFFNASLQFANMDIVMDYINSEASEFGFSVEYATLGDYFRAVHSDQVAWQVRDHRDFLPYSSDMHHAWTGFYASRSGLKALARRASSLLYAGESMFTRYVLLAPHPYLDPAWGLQQLQQLRWAVSEVQHHDAITGTHVPNVGDMFVEHLSTGMQGVHKLMASIIQDRSPAHSGKRGPEPGGHFAVVYNPLAWTVTTIITLTVDFPKVSITDESGLPVPAQAQRSKDMPSAYDLHVLTTIPGLSYRHYSIRPSRSSQEETGEPEPFVAKTTQFGGRLRRYGGQVGGSLVPVKNGCYIVFMDLDTNLMHSVWERQSNRKVYMTQQFMEYHANSDVWQGPISDNYVFTPSGTAEPAWEAVRMEIVEGPLVTEIRQYFYRLPTFTIYSRLARGPQGSDGALLCHHIEQEYQVGPLELNREAILRTSTSLNTGRVLYSDNNGYQMQRRPYRNYKNNTIARNYYPMVQSAFIQDRRSRLVLLSNQAHGVSSQRNGQVEVMLHRRLWNNDKWALNNDLTLNDSSVVHPVLWLLLGSRTLTSDLHQRSGLALQHQPVVMLREMNGEIAPRGSGSRQQEAVTLPPSVHLQILSIPGWKYSSNHTEHLQTLQKGHEAKADLRRVLLRLQHLYEVDQDPVLSRPVTVNLQSVLRGLGSVVSVEERSLTGTWDVSEMRRWTWSMRDPHGHRGSGTLPSPPPRGPEVTIYPKEIRTFFIHFQE", "length": 995, "header": "tr|G5E5M8-1|G5E5M8_BOVIN Isoform 1 of Alpha-mannosidase OS=Bos taurus OX=9913 GN=LOC532207 PE=3 SV=3 CANONICAL=G5E5M8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P3K0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K0/entry", "sequence": { "sequence": "MEPRGWLPLLLQLGLMWPPWAQPEPQLRVFVVPHSHMDVGWLHTVQENMQAYVTNVYNSVVEALTLEKKRRFIAVEQEYFRLWWDGVASHWQKRKVHQLVAKGRLEFVLGGQVMHDEAVTHIDDQILQLTEGHGFLYETFGVRPQISWQVDPFGASSTTPTLFALAGFNAHVISRIDYDLKEAMQDNRQLQFVWRGSRSLSAEQEIFTHVLDQFSYSKVPRYEGFNWDGEAIFPGPSLDGKYPSMEIPVTEDSIPDFTHLLGKRVLHKASWFQTAHILWPWGCDRQFFNASLQFANMDIVMDYINSEASEFGFSVEYATLGDYFRAVHSDQVAWQVRDHRDFLPYSSDMHHAWTGFYASRSGLKALARRASSLLYAGESMFTRYVLLAPHPYLDPAWGLQQLQQLRWAVSEVQHHDAITGTHVPNVGDMFVEHLSTGMQGVHKLMASIIQDRSPAHSGKRGPWGHTVDPVLLVYNPLAWTVTTIITLTVDFPKVSITDESGLPVPAQAQRSKDMPSAYDLHVLTTIPGLSYRHYSIRPSRSSQEETGEPEPFVAKTTQFGGRLRRYGGQVGGSLVPVKNGCYIVFMDLDTNLMHSVWERQSNRKVYMTQQFMEYHANSDVWQGPISDNYVFTPSGTAEPAWEAVRMEIVEGPLVTEIRQYFYRLPTFTIYSRLARGPQGSDGALLCHHIEQEYQVGPLELNREAILRTSTSLNTGRVLYSDNNGYQMQRRPYRNYKNNTIARNYYPMVQSAFIQDRRSRLVLLSNQAHGVSSQRNGQVEVMLHRRLWNNDKWALNNDLTLNDSSVVHPVLWLLLGSRTLTSDLHQRSGLALQHQPVVMLREMNESSIHGPVHGCEAVTLPPSVHLQILSIPGWKYSSNHTEHLQTLQKGHEAKADLRRVLLRLQHLYEVDQDPVLSRPVTVNLQSVLRGLGSVVSVEERSLTGTWDVSEMRRWTWSMRDPHGHRGSGTLVLTPPRVASLTPRQTPALPLRPV", "length": 992, "header": "tr|A0ABI0P3K0-1|A0ABI0P3K0_BOVIN Computationally mapped isoform of Alpha-mannosidase OS=Bos taurus OX=9913 GN=LOC532207 PE=3 SV=1 CANONICAL=G5E5M8-1" }, "locus": { "chromosome": "6", "start_pos": 113096527, "end_pos": 113057646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152928.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152928.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105565.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105565.1" } ] } }, { "isoform_ac": "G5E5M8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5M8/entry", "sequence": { "sequence": "MEPRGWLPLLLQLGLMWPPWAQPEPQLRVFVVPHSHMDVGWLHTVQENMQAYVTNVYNSVVEALTLEKKRRFIAVEQEYFRLWWDGVASHWQKRKVHQLVAKGRLEFVLGGQVMHDEAVTHIDDQILQLTEGHGFLYETFGVRPQISWQVDPFGASSTTPTLFALAGFNAHVISRIDYDLKEAMQDNRQLQFVWRGSRSLSAEQEIFTHVLDQFSYSKVPRYEGFNWDGEAIFPGPSLDGKYPSMEIPVTEDSIPDFTHLLGKRVLHKASWFQTAHILWPWGCDRQFFNASLQFANMDIVMDYINSEASEFGFSVEYATLGDYFRAVHSDQVAWQVRDHRDFLPYSSDMHHAWTGFYASRSGLKALARRASSLLYAGESMFTRYVLLAPHPYLDPAWGLQQLQQLRWAVSEVQHHDAITGTHVPNVGDMFVEHLSTGMQGVHKLMASIIQDRSPAHSGKRGPEPGGHFAVVYNPLAWTVTTIITLTVDFPKVSITDESGLPVPAQAQRSKDMPSAYDLHVLTTIPGLSYRHYSIRPSRSSQEETGEPEPFVAKTTQFGGRLRRYGGQVGGSLVPVKNGCYIVFMDLDTNLMHSVWERQSNRKVYMTQQFMEYHANSDVWQGPISDNYVFTPSGTAEPAWEAVRMEIVEGPLVTEIRQYFYRLPTFTIYSRLARGPQGSDGALLCHHIEQEYQVGPLELNREAILRTSTSLNTGRVLYSDNNGYQMQRRPYRNYKNNTIARNYYPMVQSAFIQDRRSRLVLLSNQAHGVSSQRNGQVEVMLHRRLWNNDKWALNNDLTLNDSSVVHPVLWLLLGSRTLTSDLHQRSGLALQHQPVVMLREMNGEIAPRGSGSRQQEAVTLPPSVHLQILSIPGWKYSSNHTEHLQTLQKGHEAKADLRRVLLRLQHLYEVDQDPVLSRPVTVNLQSVLRGLGSVVSVEERSLTGTWDVSEMRRWTWSMRDPHGHRGSGTLPSPPPRGPEVTIYPKEIRTFFIHFQE", "length": 995, "header": "tr|G5E5M8-1|G5E5M8_BOVIN Isoform 1 of Alpha-mannosidase OS=Bos taurus OX=9913 GN=LOC532207 PE=3 SV=3 CANONICAL=G5E5M8-1" }, "locus": { "chromosome": "6", "start_pos": 113097774, "end_pos": 113057646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026090.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026090.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026090.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026090.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ], "pmid": "" }, { "name": "alpha-mannosidase activity", "id": "GO:0004559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004559", "evidence": [ { "database": "UniProtKB", "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mannose metabolic process", "id": "GO:0006013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006013", "evidence": [ { "database": "UniProtKB", "id": "G5E5M8", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "84971", "name": "", "equation": "alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-D-GlcNAc + H2O = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-D-GlcNAc + D-mannose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHP0-1", "G5E5M8-1" ], "evidence": [ { "id": "84971", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84971" } ] }, { "id": "84987", "name": "", "equation": "alpha-D-Man-(1->6)-beta-D-Man-(1->4)-D-GlcNAc + H2O = 4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine + D-mannose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHP0-1", "G5E5M8-1" ], "evidence": [ { "id": "84987", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84987" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BHP0", "gene_name": "LOC523503", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "E1BHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHP0" } ] } ] }, { "uniprot_ac": "G5E5M8", "gene_name": "LOC532207", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "G5E5M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5M8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5M8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 995, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", 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"MLTRRPGARSAVAGLGAESPDTQVKAPVSPRLSGGRHRPGAYLDMKIHFEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEREHQIREQILQQRKQKVEEVTEKFQRAHIPFSQRRRTVLQRPVLPLEDALKQIQESNLKSEVNLPSSHRPIINWRAIDNDLPSSLSKNDHKHQKYLISKINCGQEMENSKANLTTNKDAFQLKLEETQKLLEDQHLSSLQKFRDEVNQIINSETLSSIDSLEAGEREEIYLTLNKEPSTSVQQQNSISLKLANLQSTNLSCFDEDKLSFSKTQHINNWLINIDDPNIFSDIFSKPNVLPDSSKCFNSKEQNPSALSRTEERAVNTANNSVAILHSPSIFVQDKKSKNTSETSVIRTTDSSSGAFKRERPLVTESPKFKFSKAWATPDSLTQEITIISDQEKYSEMTQENRTTSVPTSFVPLATPLVLPSNTQSARPLPKSSIHIKEIDPVQCSDKLGEMKDIKDEKTKYSNCNEEELSSFSDNFQVACILHNSDSEDKQKIHEASKSLSNIISNCDLVSQHKKMKYNICEKNSVRFLKSILKKESKYEHDYFKALVTNQGFKLGNQKAADIRDSIELTKEKGKSAETPKTIKKLRWFDETGNTRKNAEDSHLLKSRKRVSQQWSQPSHIRAKSGAASNMPSIPASAVDSANKKEPKDDFISENVTALGGSGTDHVPLNCFIPSGYNTAKQAWPASTEEESISPVKSGGSKTQKTNPQRSEAKVIRRTRSAKVQSGFVCMNRKGTVTRPQSASKANTFVQAQGKLIVPHPPPTSQLNIRSCKNVQASQCQSVMPENSQNISTCNYFNSKHMLPTEYKLNQWNQESSLPLPHVCSDLVTVMPALPYCSSECQTLTKINHSHGRQTVAPQDGTLYCPQRHPTYEESHPSVTLKTTREELVPLWKRQHNILGQNEKAADSSVTRRKRIVENKHKILLEQKRQNPGSVGQKYSEQMNNFGQSIQLSSSEPKQTTRGTSNIEEVSGSTSEFLMAENLVKASVPEDEILTVMNSKQLQQTNLALNKMQQFNICALSAEEQKILQSLNHLNERLYYIQETICKNPSIKSTLQIIPLL", "length": 1103, "header": "tr|G5E5N8-1|G5E5N8_BOVIN Isoform 1 of Centrosomal protein 126 OS=Bos taurus OX=9913 GN=CEP126 PE=4 SV=3 CANONICAL=G5E5N8-1" }, "isoforms": [ { "isoform_ac": "G5E5N8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5N8/entry", "sequence": { "sequence": "MLTRRPGARSAVAGLGAESPDTQVKAPVSPRLSGGRHRPGAYLDMKIHFEKNLEEERQILLQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEREHQIREQILQQRKQKVEEVTEKFQRAHIPFSQRRRTVLQRPVLPLEDALKQIQESNLKSEVNLPSSHRPIINWRAIDNDLPSSLSKNDHKHQKYLISKINCGQEMENSKANLTTNKDAFQLKLEETQKLLEDQHLSSLQKFRDEVNQIINSETLSSIDSLEAGEREEIYLTLNKEPSTSVQQQNSISLKLANLQSTNLSCFDEDKLSFSKTQHINNWLINIDDPNIFSDIFSKPNVLPDSSKCFNSKEQNPSALSRTEERAVNTANNSVAILHSPSIFVQDKKSKNTSETSVIRTTDSSSGAFKRERPLVTESPKFKFSKAWATPDSLTQEITIISDQEKYSEMTQENRTTSVPTSFVPLATPLVLPSNTQSARPLPKSSIHIKEIDPVQCSDKLGEMKDIKDEKTKYSNCNEEELSSFSDNFQVACILHNSDSEDKQKIHEASKSLSNIISNCDLVSQHKKMKYNICEKNSVRFLKSILKKESKYEHDYFKALVTNQGFKLGNQKAADIRDSIELTKEKGKSAETPKTIKKLRWFDETGNTRKNAEDSHLLKSRKRVSQQWSQPSHIRAKSGAASNMPSIPASAVDSANKKEPKDDFISENVTALGGSGTDHVPLNCFIPSGYNTAKQAWPASTEEESISPVKSGGSKTQKTNPQRSEAKVIRRTRSAKVQSGFVCMNRKGTVTRPQSASKANTFVQAQGKLIVPHPPPTSQLNIRSCKNVQASQCQSVMPENSQNISTCNYFNSKHMLPTEYKLNQWNQESSLPLPHVCSDLVTVMPALPYCSSECQTLTKINHSHGRQTVAPQDGTLYCPQRHPTYEESHPSVTLKTTREELVPLWKRQHNILGQNEKAADSSVTRRKRIVENKHKILLEQKRQNPGSVGQKYSEQMNNFGQSIQLSSSEPKQTTRGTSNIEEVSGSTSEFLMAENLVKASVPEDEILTVMNSKQLQQTNLALNKMQQFNICALSAEEQKILQSLNHLNERLYYIQETICKNPSIKSTLQIIPLL", "length": 1103, "header": "tr|G5E5N8-1|G5E5N8_BOVIN Isoform 1 of Centrosomal protein 126 OS=Bos taurus OX=9913 GN=CEP126 PE=4 SV=3 CANONICAL=G5E5N8-1" }, "locus": { "chromosome": "15", "start_pos": 6880855, "end_pos": 6772836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026683.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026683.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026683.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026683.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "G5E5N8", "url": "https://www.uniprot.org/uniprotkb/G5E5N8" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "G5E5N8", "url": "https://www.uniprot.org/uniprotkb/G5E5N8" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "G5E5N8", "url": "https://www.uniprot.org/uniprotkb/G5E5N8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "G5E5N8", "url": "https://www.uniprot.org/uniprotkb/G5E5N8" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "G5E5N8", "url": "https://www.uniprot.org/uniprotkb/G5E5N8" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "G5E5N8", "url": "https://www.uniprot.org/uniprotkb/G5E5N8" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "G5E5N8", "url": "https://www.uniprot.org/uniprotkb/G5E5N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 832, "end_pos": 834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 890, "end_pos": 892, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5N8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1103, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5N8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5N8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 697, "end_pos": 699 }, { "start_pos": 832, "end_pos": 834 }, { "start_pos": 890, "end_pos": 892 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5P7-1", "uniprot_ac": "G5E5P7", "uniprot_id": "G5E5P7_BOVIN", "mass": { "chemical_mass": 58011.0, "monoisotopic_mass": 58011.0 }, "refseq": { "ac": "NP_001382428", "name": "T-complex protein 11 X-linked protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382428" }, "gene_names": [ { "name": "LOC522334", "type": "recommended", "evidence": [ { "id": "G5E5P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5P7" } ] }, { "name": "LOC522334", "type": "synonym", "evidence": [ { "id": "NP_001382428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382428" } ] }, { "name": "TCP11X2", "type": "synonym", "evidence": [ { "id": "NP_001382428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382428" } ] } ], "protein_names": [ { "name": "T-complex 11 family, X-linked 2", "type": "recommended", "evidence": [ { "id": "G5E5P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5P7/entry#names_and_taxonomy" } ] }, { "name": "T-complex protein 11 X-linked protein 2", "type": "synonym", "evidence": [ { "id": "NP_001382428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382428" } ] }, { "name": "t-complex 11 family, X-linked 2", "type": "synonym", "evidence": [ { "id": "NP_001382428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382428" } ] }, { "name": "t-complex 11 homolog", "type": "synonym", "evidence": [ { "id": "NP_001382428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382428" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5P7", "url": "https://www.uniprot.org/uniprotkb/G5E5P7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC522334", "url": "https://www.uniprot.org/uniprotkb/G5E5P7", "locus": {} } ], "crossref": [ { "id": "G5E5P7", "url": "https://alphafold.ebi.ac.uk/entry/G5E5P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020522", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020522", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "522334", "url": "https://www.ncbi.nlm.nih.gov/gene/522334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522334", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522334", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMETMYN", "url": "https://omabrowser.org/oma/group/FMETMYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5P7", "url": "https://www.orthodb.org/?gene=G5E5P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001382428", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382428", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5P7", "url": "https://www.uniprot.org/uniprotkb/G5E5P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5P7-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKMEKTVHQNDSNEAESGAHKPETPEQTQENQSFCLDDHSAASRPEVLSVTDLIETVNEISRLSIAHEIVVNQDFYMEDGVLPPNSLEGRIMETMYKAFWDHLKVQLSSTPADFTSALELLKEVKEILLSLLLPRQNSLRDEIEEALDIDLLKQEAEHGALDVPHLSNYILNLMTLLCAPVRDEAVRKLESITDPVQLLRGIFHVLGLMKMDMVNHTIQSFRPYLKEHSIQYERAKFQELLNKQPNLLDCTTKWLTKTALDLTTAPSSSPDSPSSSSMAHSSPNWAVDNPQLPSSTMVLYQGYLNLLLWDLDSKEFPETLLMDKIRLQDMESQLKQLAILASVLLVARSFSGSALFSSTEFVNKLKHITKALMEEFNSRPEEAMVSVSEQVSQKIHERLKDMGLTALSSEKKACLRGQLQNIAKKENRVRNIVDQRIHLFLKGCLVRGMQESLLDFPVGLTLIKGELTKLGWKFFNLMRHNQQVFSPYYDEILKDIIPPAQAQETEVESI", "length": 511, "header": "tr|G5E5P7-1|G5E5P7_BOVIN Isoform 1 of T-complex 11 family, X-linked 2 OS=Bos taurus OX=9913 GN=LOC522334 PE=3 SV=2 CANONICAL=G5E5P7-1" }, "isoforms": [ { "isoform_ac": "G5E5P7-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P7/entry", "sequence": { "sequence": "MPKMEKTVHQNDSNEAESGAHKPETPEQTQENQSFCLDDHSAASRPEVLSVTDLIETVNEISRLSIAHEIVVNQDFYMEDGVLPPNSLEGRIMETMYKAFWDHLKVQLSSTPADFTSALELLKEVKEILLSLLLPRQNSLRDEIEEALDIDLLKQEAEHGALDVPHLSNYILNLMTLLCAPVRDEAVRKLESITDPVQLLRGIFHVLGLMKMDMVNHTIQSFRPYLKEHSIQYERAKFQELLNKQPNLLDCTTKWLTKTALDLTTAPSSSPDSPSSSSMAHSSPNWAVDNPQLPSSTMVLYQGYLNLLLWDLDSKEFPETLLMDKIRLQDMESQLKQLAILASVLLVARSFSGSALFSSTEFVNKLKHITKALMEEFNSRPEEAMVSVSEQVSQKIHERLKDMGLTALSSEKKACLRGQLQNIAKKENRVRNIVDQRIHLFLKGCLVRGMQESLLDFPVGLTLIKGELTKLGWKFFNLMRHNQQVFSPYYDEILKDIIPPAQAQETEVESI", "length": 511, "header": "tr|G5E5P7-1|G5E5P7_BOVIN Isoform 1 of T-complex 11 family, X-linked 2 OS=Bos taurus OX=9913 GN=LOC522334 PE=3 SV=2 CANONICAL=G5E5P7-1" }, "locus": { "chromosome": "X", "start_pos": 50028763, "end_pos": 50014328, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027341.7", "url": 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"MPKSEKIISKKDSSPSENGSPKPETSSKNQEDKTSSEVHSAENQLAAISNEDTGKVNEVSKLNVASEIAIEKNDLPEDSPESQFVETMYNAFWDHLRDQLSQTPPDFSCVLELIKNIKQILMALLLPRQNLLRNEIEEVLDLDLLKQETEHGALDILHLSHYILNLMALMCAPIRDEAVKELENIKDPVQLLRGIFQVLGLMKMDMVNYTIKNIRPYLQEHSIQYERAKFQELLDKQPDRLDCTTKWMTRAATEIITSLSSLSVTSCISSGVISSFPTPKPDPDPPSLTTVLYQGYLNLVLRDHGNEEFPETLLMDKARLQTMRSKFRHLTILASVLLVARSFSCGVLFSSPEFVDKLKCITKALTEDFSSKPEESMLSVSEQVSQEIHQGLKDTGLTALSSENRASLVGQLRNIAKKENCIRIIIEQRMHLFLKCCLIRGMQESLLDFPGCFLFIEPELAELGWKFVNLMHHNQHVFSPYYAEILKNIISTQNDEDEEKPIK", "length": 503 }, "evidence": [ { "id": "G5E5P7", "url": "https://omabrowser.org/oma/group/G5E5P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5H9J9-1", "protein_name": "T-complex protein 11-like X-linked protein 2", "gene_name": "TCP11X2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377509" }, "gene_names": [ { "name": "OR52Z1", "type": "recommended", "evidence": [ { "id": "G5E5Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q2" } ] }, { "name": "OR52Z1", "type": "synonym", "evidence": [ { "id": "NP_001377509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377509" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E5Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52Z1", "type": "synonym", "evidence": [ { "id": "NP_001377509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377509" } ] }, { "name": "olfactory receptor family 52 subfamily Z member 1", "type": "synonym", "evidence": [ { "id": "NP_001377509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377509" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q2", "url": "https://www.uniprot.org/uniprotkb/G5E5Q2#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5Q2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5Q2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 297, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5Q9-1", "uniprot_ac": "G5E5Q9", "uniprot_id": "G5E5Q9_BOVIN", "mass": { "chemical_mass": 102220.0, "monoisotopic_mass": 102220.0 }, "refseq": { "ac": "XP_005227578", "name": "ubiquitin carboxyl-terminal hydrolase 26", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227578" }, "gene_names": [ { "name": "USP26", "type": "recommended", "evidence": [ { "id": "G5E5Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ] }, { "name": "USP26", "type": "synonym", "evidence": [ { "id": "XP_005227578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227578" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase", "type": "recommended", "evidence": [ { "id": "G5E5Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "G5E5Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 26", "type": "synonym", "evidence": [ { "id": "XP_005227578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227578" } ] } ], "function": [ { "annotation": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9#function" }, { "database": "UniProtKB", "id": "RU366025", "url": "https://www.uniprot.org/uniprotkb/RU366025#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "USP26", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9", "locus": { "chromosome": "X", "start_pos": 16898145, "end_pos": 16944391, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021344", "url": "https://www.ensembl.org/id/ENSBTAG00000021344" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021344", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021344", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "517081", "url": "https://www.ncbi.nlm.nih.gov/gene/517081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517081", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517081", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHLHLTF", "url": "https://omabrowser.org/oma/group/NHLHLTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5Q9", "url": "https://www.orthodb.org/?gene=G5E5Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005227578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5Q9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPVAAHGFVQLWNKKNGTSKSKEAIVELSGKKKKTKLVIHFCNGESRTFELHNNIKNVIVRSYGEKVNHLHLTFQNNSFFFMEKISSKDVKTLKAFLDGVCQNHLPPSIRPDVDSSASASTTVQKIVDETSFQKVGKKSNSQSSEKEEKNGTPSSASESLTSTYEQLLEDEYGKRNKKLSWDFQNESSSVKKRKSKRHLLRIVSHSEKKELRIKGLKQSKLDLDFLFKISPYLHGTNLVPKLSENIYFTFLSEAEYDKDDPYWDRLKLTLDYYPEKLWQGFPNLGNTCYMNAVLQSLFLIPSFGDDLLNRSYPWCKIPPDALSMCLAQMFVLKDIYNINIKKRLLVNIKKTISAVAEIFANNRQNDAHEFLGHYLSQMKENMEKLNTLGKTKIESKEERSPQPFFAGSAAKQALLCPVITNFEFELLCSITCKGCGHTVLKTEVNNYLSINPPQGQQALPFSIQSSLDLFFGTENLEYTCEQCKHKKSHIKYTFSRLPRVLIVHLKRYNFIQFRSLKKDDQEVIISKNLKISSYCNENTRPPFPLNKKAHLMNLKVLKIFRNINSEAISKLTPSAKMALEFMNSLPSHIVPDEEPEPQKDHVHHEDSREEEKQKDLGKCSVLEILDSALANSQDGIIVARELLAVALMMNMEDGSFSLREITVSDPDVCQRVFENPKLKDDERMSMFADFDAVAKTTEDKDENAKISEVSSVAEQTPDKERMKTYEQALWLALLQSIPKTKTQKKKCTEKLKRPKESGVRGTKVKSPGASGRNKKPGKKGSLRTEKTEAASNEPKGEAEMEDRQAYRLIGVLSHLGKSLNSGHYICDAYDFVRQEWFTYNDLQVSNIEEATMQKARLSSGYVFFYMHNEIFEELLERESSPPSSTEAGKTSQEQE", "length": 896, "header": "tr|G5E5Q9-1|G5E5Q9_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Bos taurus OX=9913 GN=USP26 PE=3 SV=1 CANONICAL=G5E5Q9-1" }, "isoforms": [ { "isoform_ac": "G5E5Q9-1", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9/entry", "sequence": { "sequence": "MDPVAAHGFVQLWNKKNGTSKSKEAIVELSGKKKKTKLVIHFCNGESRTFELHNNIKNVIVRSYGEKVNHLHLTFQNNSFFFMEKISSKDVKTLKAFLDGVCQNHLPPSIRPDVDSSASASTTVQKIVDETSFQKVGKKSNSQSSEKEEKNGTPSSASESLTSTYEQLLEDEYGKRNKKLSWDFQNESSSVKKRKSKRHLLRIVSHSEKKELRIKGLKQSKLDLDFLFKISPYLHGTNLVPKLSENIYFTFLSEAEYDKDDPYWDRLKLTLDYYPEKLWQGFPNLGNTCYMNAVLQSLFLIPSFGDDLLNRSYPWCKIPPDALSMCLAQMFVLKDIYNINIKKRLLVNIKKTISAVAEIFANNRQNDAHEFLGHYLSQMKENMEKLNTLGKTKIESKEERSPQPFFAGSAAKQALLCPVITNFEFELLCSITCKGCGHTVLKTEVNNYLSINPPQGQQALPFSIQSSLDLFFGTENLEYTCEQCKHKKSHIKYTFSRLPRVLIVHLKRYNFIQFRSLKKDDQEVIISKNLKISSYCNENTRPPFPLNKKAHLMNLKVLKIFRNINSEAISKLTPSAKMALEFMNSLPSHIVPDEEPEPQKDHVHHEDSREEEKQKDLGKCSVLEILDSALANSQDGIIVARELLAVALMMNMEDGSFSLREITVSDPDVCQRVFENPKLKDDERMSMFADFDAVAKTTEDKDENAKISEVSSVAEQTPDKERMKTYEQALWLALLQSIPKTKTQKKKCTEKLKRPKESGVRGTKVKSPGASGRNKKPGKKGSLRTEKTEAASNEPKGEAEMEDRQAYRLIGVLSHLGKSLNSGHYICDAYDFVRQEWFTYNDLQVSNIEEATMQKARLSSGYVFFYMHNEIFEELLERESSPPSSTEAGKTSQEQE", "length": 896, "header": "tr|G5E5Q9-1|G5E5Q9_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Bos taurus OX=9913 GN=USP26 PE=3 SV=1 CANONICAL=G5E5Q9-1" }, "locus": { "chromosome": "X", "start_pos": 16903294, "end_pos": 16900607, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135937.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135937.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103926.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103926.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:517081", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517081", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A5S1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Usp26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPVLIHAQVQLWSAKAGMSKSRNAFIETFIGKREVKLILYFSTGKIKALQLYNNIKSVVLRTYGEDQNYLHLTFKNNDFLFVEKLTTMDARRLKRFLDKIYQSNLRAARRSGERPGDPSTSAQELSSSPPEGHLKASSACFESAKESEMCLFRQLPLLPPSSASLNAVGLLESQFMKRKRFFLGAEKEKQNLKGSTREFETNLVVSISNEKGKERGVRAVEISKAGFGFPFETNYPEEGSVNVRDLNDLITKLFSPLLFETHYIENGLDWHEYMETFLLDPEKSWQGLPNVGNTCYINVVLQSLCSIPLFVNDLFNQGFPWIKPPKDDFNMRLMQLLVLKDIYNARTRQKLLIGITKALPIFGEVFAADRQNDAHEFLSLCLVQLKETVQRVNMMWQSENESGDYYLLREIFANYTSINRTPVCPVTNNFEFELLSSIFCKACGLTVFKREPSRYLSINIPQGMKDQNMSIQSSLDLFFRAEELEHRCERCLYNKSVALHKFGRLPRVIIVHLKRYSFSESRIMNKDEQHIVISKYLRLSCHCNKNTKPPQPLLPNEHVKNLDLLRPLEELGSEILKLSSNSGRTSRSKVFPTVNIRSDKELEVQNGKRVSEVSSGSAQQEDPGKGANVVRSELTNETETIKHEKEYVLSDLDSGSISEERSQKCQEAEKCNKEALPQSCPKPSSQEQTENLGKPAVSHTQNGSLSSQGSSDSSKSPGCNDVFDKAKPTSKVEPQKLNQKEDNIYRLVSIINHIGNSPNGGHYINDAFDFRKQSWFTYSDLQVTGIQEDLVYKARLSTGYVFFYMHNDIFEELLAKEAWSTSTSKG", "length": 827 }, "evidence": [ { "id": "G5E5Q9", "url": "https://omabrowser.org/oma/group/G5E5Q9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RTE2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAALVAHGFVQIWSRKTGMSKSKEAFIQTVERKSKVRLVVYFRTGEHTTFRLSNNIKSVVLRSYGKKQNHVHLTFQDNSFLFIEKLSSRDAENLKAFLDRVHENNLQPPIRPDRDGSVFASTAVRKPVNKTSFHKTCKKSGSPSFEKGGKNETPDLEKMPLFASKSSTLTWEELLENGYGKRKKMLSSGSEMNRNFLKENIFVRKKRSKTNPFRHASHKERKESRLKQNKKLEFGPSFKISSTGKPYLDGVGLLQMLTKNIYLAFLSESKYGEDDPDWDKLKMTLDFYPEKLWQGFPNLGNTCYMNAVLQSLFSIPSFADDLLSQGFPWGKIPLDALNMCLAQLLVLKDIYNIKIKERLLVNIKKAISAVAEIFSDNIQNDAHEFLGQCLDQMKENMGQLNSIWETTFESEQGDSPQQVLTGSTATEMLVCPVITNFEFELLCSIVCKACGQVVLKTEVSNYLSINLPQGTEALPLSIQSSFDHFFGAEELEYQCEKCKHRGSVAVHKFGRLPRVLIVHLKRYSFNEFWSLKKDDQEVIISKYLKLSSHCSESTKPPLPLSKNAHIREFQILKIFQRINSEIFGLSTPSAEPTSESKDSLAAHIGSEKEAESQKYQILDKGLSGEQQKDLGKSTPNVMDSTLLNSGDGAAIARELLAVSLMMDLEDNFLSPKGKPTSSTCQEVPENPKLKKCKRSNMFVDLEGVTETIKHVCKDKPSRISEVFHQESEQAQQYERLRLYEQALWLALLQSLPKPGARYTKNPRRPTEVHFQGADVNSLGALGSDKNPGNKKCLDRKTEPETKKPKRNAEMEDPHAYRLIGVVSHLGKTPNSGHYISDAYDFERQVWFTYNDLQVSSIQEAPMQEARLCTGYIFFYMHNEIFEELLEREENSQPHSTEAGKTPRE", "length": 904 }, "evidence": [ { "id": "G5E5Q9", "url": "https://omabrowser.org/oma/group/G5E5Q9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99MX1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26", "gene_name": "Usp26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPILINAQVQMWSAKAGMSKSRNALIETCVGKREVKLILYFSTGKIKTLQLHDNIKSVVLQTYGEDQNYLHLTFKNNDFLFVEKLTTTDARRLKRFLDKTSQGSIRPARSDERCGEPSTSAQELNGSGSSCETNSECFESPKESEMCMFRELSLLPSSSTFLHNVGLLENQFIKRKRFFSDLAKNEKQSNLKDSIRDFEANLVVCISNEKGKERNVREVDISKPGFGFPFETNYPEDSGVDVRDLNDLITKLFSPVLLETHCIENGLEWHEYMKTYLLYPEKLWQGLPNVGNTCYINVVLQSLCSIPLFINDLFNQGFPWIKAPKDDFNMLLMQLLVLKDIYNARFRQKLLIGITKALPIFGEIFAVDRQNDAHEFLSLCLVQLKETFQRVTMMWQSENDSGDFYLLKDIFADYATINKMPVCPVTNNFEFELLSSIFCKACGLTLFKGEPSRYLSINIPQGGKDMSIQSTLDLFFSAEELEHRCEKCLYNKSVSFHRFGRLPRVIIVHLKRYHFNESWVMKKDERPILVSKYLRLSCHCSKSTKPPPPLRPGEHVKNLDLLKPLEVLGSEILKLPFNSVRTSRSKGFETINITSNRESEAQSGKRVSEVLSGKVQQENSGKGDTAHIVGSELTKETEKLKKHEEEHRPSDLDSGSIREAQKYQQAEKCNEGRSDKQISLEALTQSRPKPISQEQTENLGKTTLSHTQDSSQSSQSSSDSSKSSRCSDDLDKKAKPTRKVDPTKLNKKEDNVYRLVNIINHIGNSPNGGHYINDAFDFKRQSWFTYSDLHVTRTQEDFVYRGRSSTGYVFFYMHNDIFEELLAKETQSTSTSKG", "length": 835 }, "evidence": [ { "id": "G5E5Q9", "url": "https://omabrowser.org/oma/group/G5E5Q9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXU7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26", "gene_name": "USP26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVVLKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGKGGSVFSSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLTSKLTLTCGELSENQHKKRKRMLSSSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECESSCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWPATKESKDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPLAHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKFVAFDRIINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNLLRPTKLNLQKSNRNSLLALGSNKNPRNKDILDKIKSKAKETKRNDDKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFEEMLKREENAQLNSKEVEETLQKE", "length": 913 }, "evidence": [ { "id": "G5E5Q9", "url": "https://omabrowser.org/oma/group/G5E5Q9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q9", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-5696605", "name": "USP12, USP26 deubiquitinate AR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5D9H7-1", "G5E5Q9-1" ], "evidence": [ { "id": "R-BTA-5696605", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696605" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A5D9H7", "gene_name": "USP12", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A5D9H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D9H7" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A5D9H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D9H7" } ] } ] }, { "uniprot_ac": "G5E5Q9", "gene_name": "USP26", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "G5E5Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "G5E5Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q9" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 280, "end_pos": 869, "start_aa": "Gln", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 17, "end_pos": 19 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5S1-1", "uniprot_ac": "G5E5S1", "uniprot_id": "G5E5S1_BOVIN", "mass": { "chemical_mass": 36624.0, "monoisotopic_mass": 36624.0 }, "refseq": {}, "gene_names": [ { "name": "OR2T2", "type": "recommended", "evidence": [ { "id": "G5E5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5S1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5S1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E5S1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5S1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2T2", "url": "https://www.uniprot.org/uniprotkb/G5E5S1", "locus": { "chromosome": "7", "start_pos": 42118946, "end_pos": 42117972, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034743", "url": "https://www.ensembl.org/id/ENSBTAG00000034743" } ] } } ], "crossref": [ { "id": "G5E5S1", "url": "https://alphafold.ebi.ac.uk/entry/G5E5S1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000034743", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034743", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SISYTHI", "url": "https://omabrowser.org/oma/group/SISYTHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5S1", "url": "https://www.orthodb.org/?gene=G5E5S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G5E5S1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5S1-1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VNMETVLQNSTDFILLGLITHPTFPGFIFAVVFSIFLVAVTANMVMILLIHTDSHLHTPMYFLLSQLSIMDTVYICITVPKMLQDLLSKEKTISFLGCALQIFLYLTLIGGEFFLLGLMAYDRYVAVCNPLRYPLLMNRRICLFMVVGSWVGGSLDGFMLTPFTMSFPYCGSREINHFFCEIPAVLKLSCIDTSLYQTLMYACCVLMLLIPISIISVSYTRILLTVHRMNSAEGRRKAFATCSSHIVVVIIFYGAAFYTNVLPQSYHTPEKDKVVSAFYTILTPMLNPLIYSLRNKDVATALRRIQGRCTYSQKVRAGDVSKKY", "length": 324, "header": "tr|G5E5S1-1|G5E5S1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2T2 PE=3 SV=1 CANONICAL=G5E5S1-1" }, "isoforms": [ { "isoform_ac": "G5E5S1-1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1/entry", "sequence": { "sequence": "VNMETVLQNSTDFILLGLITHPTFPGFIFAVVFSIFLVAVTANMVMILLIHTDSHLHTPMYFLLSQLSIMDTVYICITVPKMLQDLLSKEKTISFLGCALQIFLYLTLIGGEFFLLGLMAYDRYVAVCNPLRYPLLMNRRICLFMVVGSWVGGSLDGFMLTPFTMSFPYCGSREINHFFCEIPAVLKLSCIDTSLYQTLMYACCVLMLLIPISIISVSYTRILLTVHRMNSAEGRRKAFATCSSHIVVVIIFYGAAFYTNVLPQSYHTPEKDKVVSAFYTILTPMLNPLIYSLRNKDVATALRRIQGRCTYSQKVRAGDVSKKY", "length": 324, "header": "tr|G5E5S1-1|G5E5S1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2T2 PE=3 SV=1 CANONICAL=G5E5S1-1" }, "locus": { "chromosome": "7", "start_pos": 42118943, "end_pos": 42117972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028897.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028897.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028897.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028897.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0U1RQ01-1", "protein_name": "Olfactory receptor", "gene_name": "Or2t35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METIYQNSTDFILLGLITHPKFPGLIFAVVFSIFVVAVTANLVIIMLIHVDSHLHTPMYFLLSQLSIMDTVYICITVPKMLQDLLSKEKTISFLGCALQIFFYLTLIGGEFLLLGLMAYDRFVAVCNPLRYQIIMNPRVCLLMVLGSWAGGSLDGFMLTPVTMSFPYCGSLEINHFFCEIPAVLKLSCRDTSLYETLMYACCVLMLLIPISFISVSYTRILITVYHMSSAEGRRKAFTTCSSHIIVVSIFYGAAFYTNVLPHSYHTPEKDKVVSAFYTILTPMLNPLIYSLRNRDVAVALRKVLRKYASSQRLRVRHIPEKY", "length": 322 }, "evidence": [ { "id": "G5E5S1", "url": "https://omabrowser.org/oma/group/G5E5S1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6A1I2-1", "protein_name": "Olfactory receptor", "gene_name": "Or2t35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVYKNSTDFILLGLITHPTFPGLIFAVVFSIFVVAVTANLVMIMLIRMDSRLHTPMYFLLSQLSIMDTVYICITVPKMLQDLLSKDKTISFLGCALQIFLYLTLIGGEFFLLGLMAYDRFVAVCNPLRYPIIMNPRICLLMVLGSWAGGSLDGFMLTPVTMSFPYCGSREINHFFCEIPAVLKLSCTDTSLYETLMYACCVLMLLIPISFISVSYTRILITVYHMSSAEGRRKAFTTCSSHIIVVSIFYGAAFYTNVLPHSYHTPEKDKVVSAFYTILTPMLNPLIYSLRNRDVAAALRKVLRKHASSQRFRVRHVPEKY", "length": 322 }, "evidence": [ { "id": "G5E5S1", "url": "https://omabrowser.org/oma/group/G5E5S1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IF00-1", "protein_name": "Olfactory receptor 2T2", "gene_name": "OR2T2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGMEGLLQNSTNFVLTGLITHPAFPGLLFAIVFSIFVVAITANLVMILLIHMDSRLHTPMYFLLSQLSIMDTIYICITVPKMLQDLLSKDKTISFLGCAVQIFLYLTLIGGEFFLLGLMAYDRYVAVCNPLRYPLLMNRRVCLFMVVGSWVGGSLDGFMLTPVTMSFPFCRSREINHFFCEIPAVLKLSCTDTSLYETLMYACCVLMLLIPLSVISVSYTHILLTVHRMNSAEGRRKAFATCSSHIMVVSVFYGAAFYTNVLPHSYHTPEKDKVVSAFYTILTPMLNPLIYSLRNKDVAAALRKVLGRCGSSQSIRVATVIRKG", "length": 324 }, "evidence": [ { "id": "G5E5S1", "url": "https://omabrowser.org/oma/group/G5E5S1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G5E5S1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G5E5S1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E5S1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G5E5S1", "url": "https://www.uniprot.org/uniprotkb/G5E5S1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5S1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 324, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5S1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5S1" } ], 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGPVDGLCDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRETIQHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIMLAHRLNARMAELRRSGQLPWLRPDSKTQVTVQYTQDNGAVIPMRVHTVVISVQHNEDITLEDMRRALKEQVIRAVVPARYLDEDTIYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF", "length": 396, "header": "tr|G5E5U7-1|G5E5U7_BOVIN Isoform 1 of S-adenosylmethionine synthase OS=Bos taurus OX=9913 GN=MAT1A PE=3 SV=1 CANONICAL=G5E5U7-1" }, "isoforms": [ { "isoform_ac": "G5E5U7-1", "url": "https://www.uniprot.org/uniprotkb/G5E5U7/entry", "sequence": { "sequence": 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"MAGTFLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACETAAKTGMIMVFGEITTKAQLDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGVHEEKDLEDIGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLAWLRPDTKTQVTVEYKDDHGRWVPQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVIPRDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDEEIIDIISKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYPWEKPKTLKF", "length": 382 }, "evidence": [ { "id": "G5E5U7", "url": "https://omabrowser.org/oma/group/G5E5U7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P13444-1", "protein_name": "S-adenosylmethionine synthase isoform type-1", "gene_name": "Mat1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGPVDGLCDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMIDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRMADLRRSGVLPWLRPDSKTQVTVQYVQDNGAVIPVRVHTIVISVQHNEDITLEAMREALKEQVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSKKTERDELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF", "length": 397 }, "evidence": [ { "id": "G5E5U7", "url": "https://omabrowser.org/oma/group/G5E5U7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00266-1", "protein_name": "S-adenosylmethionine synthase isoform type-1", "gene_name": "MAT1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF", "length": 395 }, "evidence": [ { "id": "G5E5U7", "url": "https://omabrowser.org/oma/group/G5E5U7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91X83-1", "protein_name": "S-adenosylmethionine synthase isoform type-1", "gene_name": "Mat1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGPVDGLCDHSLSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSNKTERELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF", "length": 396 }, "evidence": [ { "id": "G5E5U7", "url": "https://omabrowser.org/oma/group/G5E5U7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G5E5U7", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G5E5U7", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ], "pmid": "" }, { "name": "methionine adenosyltransferase activity", "id": "GO:0004478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004478", "evidence": [ { "database": "UniProtKB", "id": "G5E5U7", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E5U7", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "G5E5U7", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ], "pmid": "" }, { "name": "S-adenosylmethionine biosynthetic process", "id": "GO:0006556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006556", "evidence": [ { "database": "UniProtKB", "id": "G5E5U7", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21080", "name": "", "equation": "L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5U7-1", "Q2KJC6-1", "A0A3Q1MZ37-1" ], "evidence": [ { "id": "21080", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21080" } ] }, { "id": "R-BTA-174391", "name": "MAT1A multimers transfer Ado from ATP to L-Met", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-174390" ], "output_participant_list": [], "enzyme_list": [ "G5E5U7-1" ], "evidence": [ { "id": "R-BTA-174391", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174391" } ] }, { "id": "R-BTA-2408551", "name": "SeMet is converted to AdoSeMet by MAT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5357707" ], "output_participant_list": [ "R-ALL-5357652" ], "enzyme_list": [ "G5E5U7-1" ], "evidence": [ { "id": "R-BTA-2408551", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2408551" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-174390", "participant_name": "L-Met [cytosol]", "crossref": [ { "id": "57844", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532529", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-5357652", "participant_name": "AdoSeMet [cytosol]", "crossref": [ { "id": "62227", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5357707", "participant_name": "SeMet [cytosol]", "crossref": [ { "id": "62621", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MZ37", "gene_name": "MAT2A", "activity": [ { "ec_number": "2.5.1.6", "activity": "L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate.", "evidence": [ { "id": "A0A3Q1MZ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZ37" } ] }, { "ec_number": "2.5.1.6", "activity": "", "evidence": [ { "id": "A0A3Q1MZ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZ37" } ] } ] }, { "uniprot_ac": "G5E5U7", "gene_name": "MAT1A", "activity": [ { "ec_number": "2.5.1.6", "activity": "L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate.", "evidence": [ { "id": "G5E5U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ] }, { "ec_number": "2.5.1.6", "activity": "", "evidence": [ { "id": "G5E5U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" } ] } ] }, { "uniprot_ac": "Q2KJC6", "gene_name": "MAT1A", "activity": [ { "ec_number": "2.5.1.6", "activity": "L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate.", "evidence": [ { "id": "Q2KJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJC6" } ] }, { "ec_number": "2.5.1.6", "activity": "", "evidence": [ { "id": "Q2KJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJC6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5U7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 396, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5U7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5U7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" }, { "id": "PF02773", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02773" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S-adenosylmethionine synthetase C-terminal", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 389, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" }, { "id": "PF00438", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00438" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S-adenosylmethionine synthetase N-terminal", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 116, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5U7" }, { "id": "PF02772", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02772" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S-adenosylmethionine synthetase central", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 251, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.6", "ec_name": "L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate.", "evidence": [ { "id": "2.5.1.6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.6" }, { "id": "2.5.1.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.6" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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{ "name": "CPN1", "type": "recommended", "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ] } ], "protein_names": [ { "name": "Carboxypeptidase N catalytic chain", "type": "recommended", "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0/entry#names_and_taxonomy" } ] }, { "name": "3.4.17.3", "type": "synonym", "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0/entry#names_and_taxonomy" } ] }, { "name": "Carboxypeptidase N polypeptide 1", "type": "synonym", "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0/entry#names_and_taxonomy" } ] }, { "name": "Carboxypeptidase N small subunit", "type": "synonym", "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.", "evidence": [ { "database": "UniProtKB", "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0#function" }, { "database": "UniProtKB", "id": "ARBA00059780", "url": "https://www.uniprot.org/uniprotkb/ARBA00059780#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPN1", "url": "https://www.uniprot.org/uniprotkb/G5E5V0", "locus": { "chromosome": "26", "start_pos": 20960054, "end_pos": 20993503, "strand": "+", "evidence": [ { "database": "Ensembl 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"IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CEEYRHG", "url": "https://omabrowser.org/oma/group/CEEYRHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5V0", "url": "https://www.orthodb.org/?gene=G5E5V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-977606", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5V0-1", "url": "https://www.uniprot.org/uniprotkb/G5E5V0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDLVSIFLHLLLFKLVAPVTFRHHRYDDLVRMLYKVHNECPHITRVYSIGRSVKGRHLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRIVRLVEDTRIHIMPSMNPDGYEVAAAAQERDISGYLVGRNNANGVDLNRNFPDLNTYIYYNEKNGGPNHHLPLPDNWKSQVEPETQAVIQWIRSFNFVLSANLHGGAVVANYPYDKSLGHRVRGFRRTANTPTPDDKLFQKLAKIYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPLQGELQREWLGNREALIQFLEQVHQGIKGMVRDENYNNLADAVISVGGINHDVTSGAHGDYFRLLLPGTYTVTATAPGFDPETVSVTVGPAEPKLVNFQLKRSTPQAAPKRRIPNSGHRGRVLPKKVQPRAARKKETMMKQPQRGPA", "length": 462, "header": "tr|G5E5V0-1|G5E5V0_BOVIN Isoform 1 of Carboxypeptidase N catalytic chain OS=Bos taurus OX=9913 GN=CPN1 PE=3 SV=1 CANONICAL=G5E5V0-1" }, "isoforms": [ { "isoform_ac": "G5E5V0-1", "url": "https://www.uniprot.org/uniprotkb/G5E5V0/entry", "sequence": { "sequence": "MSDLVSIFLHLLLFKLVAPVTFRHHRYDDLVRMLYKVHNECPHITRVYSIGRSVKGRHLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRIVRLVEDTRIHIMPSMNPDGYEVAAAAQERDISGYLVGRNNANGVDLNRNFPDLNTYIYYNEKNGGPNHHLPLPDNWKSQVEPETQAVIQWIRSFNFVLSANLHGGAVVANYPYDKSLGHRVRGFRRTANTPTPDDKLFQKLAKIYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPLQGELQREWLGNREALIQFLEQVHQGIKGMVRDENYNNLADAVISVGGINHDVTSGAHGDYFRLLLPGTYTVTATAPGFDPETVSVTVGPAEPKLVNFQLKRSTPQAAPKRRIPNSGHRGRVLPKKVQPRAARKKETMMKQPQRGPA", "length": 462, "header": "tr|G5E5V0-1|G5E5V0_BOVIN Isoform 1 of Carboxypeptidase N catalytic chain OS=Bos taurus OX=9913 GN=CPN1 PE=3 SV=1 CANONICAL=G5E5V0-1" }, "locus": { "chromosome": "26", "start_pos": 20993348, "end_pos": 20960169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032932.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032932.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032859.4", "url": "https://www.ensembl.org/id/ENSBTAP00000032859.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 402, "start_aa": "Thr", "end_pos": 402, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr402", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C7M0-1", "protein_name": "Carboxypeptidase N catalytic chain", "gene_name": "CPN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGWLRPLAGTLLLLEVAAAVSFLHHRYEEMVRALFRVQSECPYVTRIYSIGRSVEGRHLYVLEFSDYPGIHEPLEPEFKYVGNMHGNEVLGRELLLQLSEFLCEEYRRGSERVTRLLHDTRIHIMPSMNPDGYEVAAKQGPDGIGYLTGRNNANGVDLNRNFPDLNTFMYYSGEISGPNHHIPLPDNWKSQVEPETLAVIQWIGSYNFVLSANLHGGAVVANYPYDKSQDQRFRSHRRTANTPTPDDKLFQKLAKTYSYAHGWMHRGWNCGDYFVDGITNGASWYSLSKGMQDFNYLYTNCFEITLELSCNKFPPKEDLERQWMANREALVAFIEEIHQGIKGMVTDKNNNGIAGAVISVQGISHDVTSGEMGDYFRLLLPGTYTVTASAEGYQPQTVTATVGPAAPSLVHFQLKQDMVKKAPERKASGTRTNNKTLQKKVVPRSVRRGTQR", "length": 453 }, "evidence": [ { "id": "G5E5V0", "url": "https://omabrowser.org/oma/group/G5E5V0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S8V7-1", "protein_name": "Carboxypeptidase N catalytic chain", "gene_name": "CPN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSDLVAIFLHLLLFKLVAPVTFRHHRYDDLVRTLYKVHNECPYITRVYSIGRSVKGRHLYVLEFSDYPGNHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNGNQRIVRLVESTRIHILPSMNPDGYEVAAAQGRNISGYLIGRNNANGVDLNRNFPDLNTYIYYNEKNGGPNHHLPLPDNWKSQVEPETQAVIQWIRSFNFVLSANLHGGAVVANYPYDKSLEHRVRGFRHPTTTPTPDDKLFQKLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPQEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLADAVISVSGINHDVTSGAQGDYFRLLLPGTYTVTATAPGFDPETVSVTVGPGEPKLVNFQLKRSTPPAAPKKRVPNSGQRVKVLPKKVQPRAARKKEMKKKQTQRAPA", "length": 461 }, "evidence": [ { "id": "G5E5V0", "url": "https://omabrowser.org/oma/group/G5E5V0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P15169-1", "protein_name": "Carboxypeptidase N catalytic chain", "gene_name": "CPN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA", "length": 458 }, "evidence": [ { "id": "G5E5V0", "url": "https://omabrowser.org/oma/group/G5E5V0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54I77-1", "protein_name": "Peptidase M14 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILTIYLLIIYFIVFIKNVVNCEIEQLMINGCEKFDESGDVCIKLKKLNFYTINSVGQPLTRDLLDYVENQLSINQDDNKLILTSENQFNVYLNEDQFKFLNEKKKEFGLEIKLNLVKNLEEILGTTIQTEMDKLKRITVLLESMRYNYNKGGSSTAYGQSPFLVRSESGIIDYNHYLNYNQLTDFMKKISNYYPNQSKLYSIGKSSLGRELWAIDLSNFQLKKNNNNKFKQNVKLVGNMHGDEVVGRQMLIYLIDHLLYRNSKVDKEYVELFENLIISIVPSMNPDGYELGQRENANHFDLNRNFPDKFVGSSSELYKKIQPEVQSIIDWSKERNFVMSANLHGGSLVANYPFDSTRDSDNGYGFGIQYPTTDDVVFRRMALTYSLNHAKMYQSKEFLGGIVNGAKWYTLRGGMQDYNYDFTNGMEITLELSSEKIPKSIELNRFWNDNRNALVKFISLPLSMSIFGRVTNNNNENLFAQIQISNIDKIVTTDPSNGYYSRLLDDGFYNVTVSSFGYKSITKSILLNPNSRENIDFILDFEN", "length": 544 }, "evidence": [ { "id": "G5E5V0", "url": "https://omabrowser.org/oma/group/G5E5V0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9EQV8-1", "protein_name": "Carboxypeptidase N catalytic chain", "gene_name": "Cpn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPDLPSAFLPLLLLSKFVTPVTFRHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGTHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNTSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKYGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRSPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCNKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLTGAVISVTGINHDVTSGEHGDYFRLLLPGTYSVTAKASGYEPKTVTVTVGPAGPTLVDFQLKRSTTQVHPVQKAPGRGQGSRAKQPRTSRKKDQAAKRHRGPA", "length": 457 }, "evidence": [ { "id": "G5E5V0", "url": "https://omabrowser.org/oma/group/G5E5V0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JJN5-1", "protein_name": "Carboxypeptidase N catalytic chain", "gene_name": "Cpn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPDLPSAFLPLLLLSKFVTPVTFRHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNNLTGAVISVTGINHDVTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTVGPAGPTVVDFQLKRSSSQVYPVQRAPGRGQGGRAKQPRTSRKKDPATKRHRGPA", "length": 457 }, "evidence": [ { "id": "G5E5V0", "url": "https://omabrowser.org/oma/group/G5E5V0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M9H7-1", "protein_name": "Carboxypeptidase SOL1", "gene_name": "SOL1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSKLRFFQSLLISTVICFFLPSINARGGHSDHIHPGDGNYSFHGIVRHLFAQEEPTPSLELTRGYMTNDDLEKAMKDFTKRCSKISRLYSIGKSVNGFPLWVIEISDRPGEIEAEPAFKYIGNVHGDEPVGRELLLRLANWICDNYKKDPLAQMIVENVHLHIMPSLNPDGFSIRKRNNANNVDLNRDFPDQFFPFNDDLNLRQPETKAIMTWLRDIRFTASATLHGGALVANFPWDGTEDKRKYYYACPDDETFRFLARIYSKSHRNMSLSKEFEEGITNGASWYPIYGGMQDWNYIYGGCFELTLEISDNKWPKASELSTIWDYNRKSMLNLVASLVKTGVHGRIFSLDKGKPLPGLVVVKGINYTVKAHQTYADYHRLLVPGQKYEVTASSPGYKSKTTTVWLGENAVTADFILIPETSSRGNQLRSSCDCSCKSCGQPLLTQFFTETNNGITLTLFVVVVFLCFLLQRRVRFNLWKQRQSSRRSITV", "length": 491 }, "evidence": [ { "id": "G5E5V0", "url": "https://omabrowser.org/oma/group/G5E5V0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ], "pmid": "" }, { "name": "peptide metabolic process", "id": "GO:0006518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006518", "evidence": [ { "database": "UniProtKB", "id": "G5E5V0", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8852809", "name": "CPN, CPB2 cleave C3a, C5a", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KIG3-1", "G5E5V0-1" ], "evidence": [ { "id": "R-BTA-8852809", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8852809" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "G5E5V0", "gene_name": "CPN1", "activity": [ { "ec_number": "3.4.17.3", "activity": "Release of a C-terminal basic amino acid, preferentially lysine.", "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ] }, { "ec_number": "3.4.17.3", "activity": "", "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" } ] } ] }, { "uniprot_ac": "Q2KIG3", "gene_name": "CPB2", "activity": [ { "ec_number": "3.4.17.20", "activity": "Release of C-terminal Arg and Lys from a polypeptide.", "evidence": [ { "id": "Q2KIG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIG3" } ] }, { "ec_number": "3.4.17.20", "activity": "", "evidence": [ { "id": "Q2KIG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIG3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5V0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 462, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5V0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5V0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V0" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 338, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.17.3", "ec_name": "Release of a C-terminal basic amino acid, preferentially lysine.", "evidence": [ { "id": "3.4.17.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.17.3" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 402 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5X2-1", "uniprot_ac": "G5E5X2", "uniprot_id": "G5E5X2_BOVIN", "mass": { "chemical_mass": 32166.0, "monoisotopic_mass": 32166.0 }, "refseq": { "ac": "NP_001376880", "name": "olfactory receptor 2AE1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376880" }, "gene_names": [ { "name": "OR2AE1", "type": "recommended", "evidence": [ { "id": "G5E5X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5X2" } ] }, { "name": "OR2AE1", "type": "synonym", "evidence": [ { "id": "NP_001376880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376880" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E5X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5X2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2AE1", "type": "synonym", "evidence": [ { "id": "NP_001376880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376880" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E619-1", "uniprot_ac": "G5E619", "uniprot_id": "G5E619_BOVIN", "mass": { "chemical_mass": 24467.0, "monoisotopic_mass": 24467.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "GTP-binding nuclear protein Ran", "type": "recommended", "evidence": [ { "id": "G5E619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E619/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.", "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619#function" }, { "database": "UniProtKB", "id": "RU363057", "url": "https://www.uniprot.org/uniprotkb/RU363057#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G5E619", "locus": {} } ], "crossref": [ { "id": "G5E619", "url": "https://alphafold.ebi.ac.uk/entry/G5E619", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014223", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014223", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00877", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00877", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QCLICIS", "url": "https://omabrowser.org/oma/group/QCLICIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24071:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24071:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E619-1", "url": "https://www.uniprot.org/uniprotkb/G5E619-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQGEPQVQFKLVLVGDGGTGKTTFVKHHLTGEFEKYVATLGVEVHPLVFLFHTNTGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVQVCENIPIVLCGNKVDIKDRKVKAKSIVFHQKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVNMPALAPPEVVMDPALAAQYEHNLEVAQTTALPDEDDDL", "length": 217, "header": "tr|G5E619-1|G5E619_BOVIN Isoform 1 of GTP-binding nuclear protein Ran OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G5E619-1" }, "isoforms": [ { "isoform_ac": "G5E619-1", "url": "https://www.uniprot.org/uniprotkb/G5E619/entry", "sequence": { "sequence": "MAAQGEPQVQFKLVLVGDGGTGKTTFVKHHLTGEFEKYVATLGVEVHPLVFLFHTNTGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVQVCENIPIVLCGNKVDIKDRKVKAKSIVFHQKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVNMPALAPPEVVMDPALAAQYEHNLEVAQTTALPDEDDDL", "length": 217, "header": "tr|G5E619-1|G5E619_BOVIN Isoform 1 of GTP-binding nuclear protein Ran OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G5E619-1" }, "locus": { "chromosome": "X", "start_pos": 52205699, "end_pos": 52203745, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018906.5", "url": "https://www.ensembl.org/id/ENSBTAT00000018906.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046975.4", "url": "https://www.ensembl.org/id/ENSBTAP00000046975.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "G5E619", "url": "https://www.uniprot.org/uniprotkb/G5E619" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", "E1BJA0-1", "A0A3Q1N147-1", "A0AAF6YME1-1", "F1MX39-1", "Q1RMJ6-1", "Q2HJ68-1", "Q2HJG3-1", "Q17QI8-1", "Q3SZA1-1", "A0ABI0NZ89-1", "A0ABI0P4Y3-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T898", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] } ] }, { 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H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1N147", "gene_name": "RAB1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] } ] }, { "uniprot_ac": "A0A3Q1NCE9", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] } ] }, { "uniprot_ac": "A0A3Q1NEF8", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] } ] }, { "uniprot_ac": "A0A3S5ZPA2", "gene_name": "RAB40B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": 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"NP_001377632", "name": "olfactory receptor family 2 subfamily D member 4", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377632" }, "gene_names": [ { "name": "OR2D4", "type": "recommended", "evidence": [ { "id": "G5E636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E636" } ] }, { "name": "OR2D4", "type": "synonym", "evidence": [ { "id": "NP_001377632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377632" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E636/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2D3", "type": "synonym", "evidence": [ { "id": "NP_001377632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377632" } ] }, { "name": "olfactory receptor family 2 subfamily D member 4", "type": "synonym", "evidence": [ { "id": "NP_001377632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377632" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377632", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377632" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E636", "url": "https://www.uniprot.org/uniprotkb/G5E636#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E636", "url": "https://www.uniprot.org/uniprotkb/G5E636" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2D4", "url": "https://www.uniprot.org/uniprotkb/G5E636", "locus": { "chromosome": "15", "start_pos": 45991732, "end_pos": 45990809, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000060748", "url": "https://www.ensembl.org/id/ENSBTAG00000060748" } ] } } ], "crossref": [ { "id": "G5E636", "url": "https://alphafold.ebi.ac.uk/entry/G5E636", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100336956", "url": "https://www.ncbi.nlm.nih.gov/gene/100336956", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336956", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336956", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGQNIIN", "url": "https://omabrowser.org/oma/group/HGQNIIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377632", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377632", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E636", "url": "https://www.uniprot.org/uniprotkb/G5E636", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E636-1", "url": "https://www.uniprot.org/uniprotkb/G5E636-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTKNQTCLTEFILLGLSSDQQTQIVLFVIFLIIYLLTVFGNLLIILLIHTDSQLHTPMYFFLKNLSFSDLLFSTTIVPQMLFHLLVTRKTISKSGCSIQMIFFLVAGCTESSLLAVMSYDRYVAVCKPLHYSTLMTQRICVQLSIGSWTSGALVSLVDTAFTLYLSYHGQNIIDHYFCEPPALLKLASEETYKAEMAIFAMGVIILLGPLSLILFSYWNILSTVIQIRAGERRLKVFSTCGSHLIVVVFFYGSTIFTYMRPNAKKMNEGDKVISVFYSVITSMMNPFIYSLRNKDVKQAFKKLFGR", "length": 307, "header": "tr|G5E636-1|G5E636_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2D4 PE=3 SV=3 CANONICAL=G5E636-1" }, "isoforms": [ { "isoform_ac": "G5E636-1", "url": "https://www.uniprot.org/uniprotkb/G5E636/entry", "sequence": { "sequence": "MGTKNQTCLTEFILLGLSSDQQTQIVLFVIFLIIYLLTVFGNLLIILLIHTDSQLHTPMYFFLKNLSFSDLLFSTTIVPQMLFHLLVTRKTISKSGCSIQMIFFLVAGCTESSLLAVMSYDRYVAVCKPLHYSTLMTQRICVQLSIGSWTSGALVSLVDTAFTLYLSYHGQNIIDHYFCEPPALLKLASEETYKAEMAIFAMGVIILLGPLSLILFSYWNILSTVIQIRAGERRLKVFSTCGSHLIVVVFFYGSTIFTYMRPNAKKMNEGDKVISVFYSVITSMMNPFIYSLRNKDVKQAFKKLFGR", "length": 307, "header": "tr|G5E636-1|G5E636_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2D4 PE=3 SV=3 CANONICAL=G5E636-1" }, "locus": { "chromosome": "15", "start_pos": 45991729, "end_pos": 45990809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000050523.5", "url": "https://www.ensembl.org/id/ENSBTAT00000050523.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047208.5", "url": "https://www.ensembl.org/id/ENSBTAP00000047208.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336956", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336956", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FJ49-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100753672", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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}, "evidence": [ { "id": "G5E636", "url": "https://omabrowser.org/oma/group/G5E636/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EP55-1", "protein_name": "Olfactory receptor", "gene_name": "Or2d4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKLNHTYLTEFILLGLSSDHQTQILLFVVFLIIYLITVFGNLLIILLIHVDSRLHTPMYFFLKILSFNDLCFSTTIVPKMLVHFLGVRKTISFAGCSVQMFSFLIMGCTESSLLAVMSYDRYIAVCKPLHYSTIMTHKVCVLLVVGSWTSGIFVSVVDTSFTLCLTYRGPNIINHYFCEPPALLKLASEETYTAEMVIFAMGIIILLGPVSLILFSYWNIISTVVQIQSGEGRLKVFSTCSSHFIVVIFFYGSTIFTYMQPNSKKMNEKDKVISVFYSIVTSMMNPFIYSLRNKDVKGALKKVLKREIR", "length": 310 }, "evidence": [ { "id": "G5E636", "url": "https://omabrowser.org/oma/group/G5E636/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": 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"https://www.uniprot.org/uniprotkb/G5E636" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E636-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E636-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E636" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E636" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E640-1", "uniprot_ac": "G5E640", "uniprot_id": "G5E640_BOVIN", "mass": { "chemical_mass": 42980.0, "monoisotopic_mass": 42980.0 }, "refseq": { "ac": "XP_003588241", "name": "probable G-protein coupled receptor 34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003588241" }, "gene_names": [ { "name": "GPR34", "type": "recommended", "evidence": [ { "id": "G5E640", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E640" } ] }, { "name": "GPR34", "type": "synonym", "evidence": [ { "id": "XP_003588241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003588241" } ] } ], "protein_names": [ { "name": "Probable G-protein coupled receptor 34", "type": "recommended", "evidence": [ { "id": "G5E640", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E640/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 34", "type": "synonym", "evidence": [ { "id": "XP_003588241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003588241" } ] } ], "function": [ { "annotation": "G-protein-coupled receptor of lysophosphatidylserine (LysoPS) that plays different roles in immune response. Acts a damage-sensing receptor that triggers tissue repair upon recognition of dying neutrophils. Mechanistically, apoptotic neutrophils release lysophosphatydilserine that are recognized by type 3 innate lymphoid cells (ILC3s) via GPR34, which activates downstream PI3K-AKT and RAS-ERK signaling pathways leading to STAT3 activation and IL-22 production. Plays an important role in microglial function, controlling morphology and phagocytosis.", "evidence": [ { "database": "UniProtKB", "id": "G5E640", "url": "https://www.uniprot.org/uniprotkb/G5E640#function" }, { "database": "UniProtKB", "id": "ARBA00045234", "url": "https://www.uniprot.org/uniprotkb/ARBA00045234#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E640", "url": "https://www.uniprot.org/uniprotkb/G5E640" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR34", "url": "https://www.uniprot.org/uniprotkb/G5E640", "locus": { "chromosome": "X", "start_pos": 101923481, "end_pos": 101972567, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020144", "url": "https://www.ensembl.org/id/ENSBTAG00000020144" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020144", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020144", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100139092", "url": "https://www.ncbi.nlm.nih.gov/gene/100139092", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100139092", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139092", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IIHKCNE", "url": "https://omabrowser.org/oma/group/IIHKCNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E640", "url": "https://www.orthodb.org/?gene=G5E640", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24233:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24233:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003588241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003588241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E640", "url": "https://www.uniprot.org/uniprotkb/G5E640", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E640-1", "url": "https://www.uniprot.org/uniprotkb/G5E640-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSQMVTMMTTSVSSWSCSSKGVHFNYSVQSPHNVSGASNFTACSMDEKLLSSVLITFYSVIFIMGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWVIALAGFLTMIILTLKKGGHNSTMCFHYRDKVNAKGEAIFNYVLVVMFWLIFLLIILSYIKIGKNLLRISKKRSKFPNSGKYATTARNSFIVLIIFTVCFVPYHAFRFVYISSQLNVSSCYWKEIVHKTNEIMLVFSSFNSCLDPVMYFLMSSNIRKIMCQLLSRRFQGEASRSESTSEFKPGYSLHDTSAVAKIQTTS", "length": 376, "header": "tr|G5E640-1|G5E640_BOVIN Isoform 1 of Probable G-protein coupled receptor 34 OS=Bos taurus OX=9913 GN=GPR34 PE=3 SV=1 CANONICAL=G5E640-1" }, "isoforms": [ { "isoform_ac": "G5E640-1", "url": "https://www.uniprot.org/uniprotkb/G5E640/entry", "sequence": { "sequence": "MRSQMVTMMTTSVSSWSCSSKGVHFNYSVQSPHNVSGASNFTACSMDEKLLSSVLITFYSVIFIMGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVWVIALAGFLTMIILTLKKGGHNSTMCFHYRDKVNAKGEAIFNYVLVVMFWLIFLLIILSYIKIGKNLLRISKKRSKFPNSGKYATTARNSFIVLIIFTVCFVPYHAFRFVYISSQLNVSSCYWKEIVHKTNEIMLVFSSFNSCLDPVMYFLMSSNIRKIMCQLLSRRFQGEASRSESTSEFKPGYSLHDTSAVAKIQTTS", "length": 376, "header": "tr|G5E640-1|G5E640_BOVIN Isoform 1 of Probable G-protein coupled receptor 34 OS=Bos taurus OX=9913 GN=GPR34 PE=3 SV=1 CANONICAL=G5E640-1" }, "locus": { "chromosome": "X", "start_pos": 101925790, "end_pos": 101924663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127787.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127787.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080628.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080628.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100139092", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139092", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LUT0-1", "protein_name": "Probable G-protein coupled receptor 34", "gene_name": "Gpr34", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTTSVNSWPCSSYGMHFITNHSDESSQNFSTVPNDTSCPMDEKLLSTVLTTFYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYVKINRSIQQRRAITTRQSIYVCCIVWAVALAGFLTMIILTLKKGGHNSTLCFHYRDRHNAKGEAIFNYVLVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNEPSCYWKRIVHKTNEIMLVLSAFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQSEASRSESTSEFKPGYSLHDLSVAAKMQYNTKGN", "length": 374 }, "evidence": [ { "id": "G5E640", "url": "https://omabrowser.org/oma/group/G5E640/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XFN0-1", "protein_name": "Probable 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"MTTTVDSWLCSSPGMHFITNDSDQVSQNFSGVSNVTSCPMDEKLLSTVLTTFYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAVADLLLIFCLPFRIMYHINQNRWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRRAITTKQSVYVCCVVWTVALAGFLTMIILTLKKGGHNSTMCFHYRDKHNAKGEAIFNFALVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNASSCYWKEIIHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQSDTSRSESTSEFKPGYSLHDLSVTVKMQYSTKGN", "length": 373 }, "evidence": [ { "id": "G5E640", "url": "https://omabrowser.org/oma/group/G5E640/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UPC5-1", "protein_name": "Probable G protein-coupled receptor 34", "gene_name": "GPR34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"MAVPINNSASNFFFILMDFPGLEMAHCWTAVPVCFIYVLSLLGNTTILYIVKSVPSLHTPMYLFLSMLSVADLGLAVSTLPSMAAVFLLGQRKVGAATCFVQLFFIHTCSVIESAVLLAMAFDRCVAIREPLRYATILTAKCIGATGLASVTRSAALHLPLPVLLGRLQFPPVNALSHSYCVHPDVLRLASSSTVVNSGLGLFVMLSTLGLDAVLILLSYVMILKTVLSIASNAGRLKALNTCISHICAVLLFYTPLISLSVIHRFGKKKLPVQIYMLLSYLHFLVPPMLNPIVYTVKTKEIRARILKMLQPSKL", "length": 315, "header": "tr|G5E6C2-1|G5E6C2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR51AG1 PE=3 SV=2 CANONICAL=G5E6C2-1" }, "isoforms": [ { "isoform_ac": "G5E6C2-1", "url": "https://www.uniprot.org/uniprotkb/G5E6C2/entry", "sequence": { "sequence": "MAVPINNSASNFFFILMDFPGLEMAHCWTAVPVCFIYVLSLLGNTTILYIVKSVPSLHTPMYLFLSMLSVADLGLAVSTLPSMAAVFLLGQRKVGAATCFVQLFFIHTCSVIESAVLLAMAFDRCVAIREPLRYATILTAKCIGATGLASVTRSAALHLPLPVLLGRLQFPPVNALSHSYCVHPDVLRLASSSTVVNSGLGLFVMLSTLGLDAVLILLSYVMILKTVLSIASNAGRLKALNTCISHICAVLLFYTPLISLSVIHRFGKKKLPVQIYMLLSYLHFLVPPMLNPIVYTVKTKEIRARILKMLQPSKL", "length": 315, "header": "tr|G5E6C2-1|G5E6C2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR51AG1 PE=3 SV=2 CANONICAL=G5E6C2-1" }, "locus": { "chromosome": "15", "start_pos": 49538956, "end_pos": 49538012, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056748.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056748.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050501.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050501.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783488", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783488", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LL53-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100765180", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"length": 315 }, "evidence": [ { "id": "G5E6C2", "url": "https://omabrowser.org/oma/group/G5E6C2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G5E6C2", "url": "https://www.uniprot.org/uniprotkb/G5E6C2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G5E6C2", "url": "https://www.uniprot.org/uniprotkb/G5E6C2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E6C2", "url": 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6C5-1", "uniprot_ac": "G5E6C5", "uniprot_id": "G5E6C5_BOVIN", "mass": { "chemical_mass": 85525.0, "monoisotopic_mass": 85525.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ADAM metallopeptidase domain 20", "type": "recommended", "evidence": [ { "id": "G5E6C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6C5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6C5", "url": "https://www.uniprot.org/uniprotkb/G5E6C5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G5E6C5", "locus": {} } ], "crossref": [ { "id": "G5E6C5", "url": "https://alphafold.ebi.ac.uk/entry/G5E6C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039873", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039873", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G5E6C5", "url": "https://www.uniprot.org/uniprotkb/G5E6C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6C5-1", "url": "https://www.uniprot.org/uniprotkb/G5E6C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377558" }, "gene_names": [ { "name": "OR13D2", "type": "recommended", "evidence": [ { "id": "G5E6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6E9" } ] }, { "name": "OR13D2", "type": "synonym", "evidence": [ { "id": "NP_001377558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377558" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6E9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 13D1", "type": "synonym", "evidence": [ { "id": "NP_001377558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377558" } ] }, { "name": "olfactory receptor family 13 subfamily D member 2", "type": "synonym", "evidence": [ { "id": "NP_001377558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377558" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E6E9", "url": "https://www.uniprot.org/uniprotkb/G5E6E9#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"MKTNFSLATISKNITGSLHVGLVNISGNESTFNCSHKPSDKHLDAIPVLYYIIFAVGFLVNTIVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSHRYDWLFGPVMCKLFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCINPFLYCFVGNRFQQKLRRVFRVPITWLQGKRENGSCGKSSSLREMETFVS", "length": 362, "header": "tr|G5E6F7-1|G5E6F7_BOVIN Isoform 1 of Type-2 angiotensin II receptor OS=Bos taurus OX=9913 GN=AGTR2 PE=3 SV=1 CANONICAL=G5E6F7-1" }, "locus": { "chromosome": "X", "start_pos": 546201, "end_pos": 545116, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052443.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052443.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051725.2", "url": "https://www.ensembl.org/id/ENSBTAP00000051725.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:407157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:407157", "resource": "KEGG Pathway" }, { "id": "R-BTA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-BTA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W622-1", "protein_name": "Type-2 angiotensin II receptor", "gene_name": "AGTR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKDNFTLVTISKNITSSLHVGLVNISGNESTFNCSHKPSDKHLDAIPILYYIIFVVGFLVNTIVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLNMAAAVVLAFIICWLPFHVLTFLDALAWMGIINSCEVIAVIDLALPFAILLGFTNSCINPFLYCFVGNRFQQKLRRVFRVPITWLQGKRESVSCRKSSSLREMETFVS", "length": 362 }, "evidence": [ { "id": "G5E6F7", "url": "https://omabrowser.org/oma/group/G5E6F7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z877-1", "protein_name": "Type-2 angiotensin II receptor", "gene_name": "AGTR2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSNYSMGITTRETLQILYTAQANSSAVLRSPPPCPLTSSSYQFSLIPAFFSVVFALGLVGNSVVVVVLCHRSSPRTVANIYIFNLAMADLLCLATLPFWATYYAQGYNWIFGSLMCKISSSVLCLNMFASIFFITCMSVDRYHAIVHPIRSQRRTPHQAYFIALVVWGLACLSSLPTFYFRDTHYIKSMEVKACIMAFPHESYAEWSVGTAFLKNALGFFIPLAVITTCYVWIRRHLIQAQEFGKNKQKRDKVLKLVAAVVVAFLICWLPFHILTFLDALAHMNIIDNCDVTGVIDTALPFGICMAFANSCVNPLVYCFIGNQFQEKLHRLFKRRVYQFNSQRESSSLRKGSCFRDTEIAVGREREPESPL", "length": 372 }, "evidence": [ { "id": "G5E6F7", "url": "https://omabrowser.org/oma/group/G5E6F7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I4R1-1", "protein_name": "Type-2 angiotensin II receptor", "gene_name": "Agtr2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKDNFGFVVTSKNVTSSLPFDGFNMSATNESVFNCSHKPSDKHLEAIPVLYYIIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWASYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRVTRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS", "length": 363 }, "evidence": [ { "id": "G5E6F7", "url": "https://omabrowser.org/oma/group/G5E6F7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P35351-1", "protein_name": "Type-2 angiotensin II receptor", "gene_name": "Agtr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS", "length": 363 }, "evidence": [ { "id": "G5E6F7", "url": "https://omabrowser.org/oma/group/G5E6F7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35374-1", "protein_name": "Type-2 angiotensin II receptor", "gene_name": "Agtr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDNFSFAATSRNITSSRPFDNLNATGTNESAFNCSHKPSDKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLALADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKGSSLREMDTFVS", "length": 363 }, "evidence": [ { "id": "G5E6F7", "url": "https://omabrowser.org/oma/group/G5E6F7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50052-1", "protein_name": "Type-2 angiotensin II receptor", "gene_name": "AGTR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS", "length": 363 }, "evidence": [ { "id": "G5E6F7", "url": "https://omabrowser.org/oma/group/G5E6F7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E6F7", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "G5E6F7", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "G5E6F7", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" } ], "pmid": "" }, { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "G5E6F7", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" } ], "pmid": "" }, { "name": "vasodilation", "id": "GO:0042311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042311", "evidence": [ { "database": "UniProtKB", "id": "G5E6F7", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "G5E6F7", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "angiotensin type II receptor activity", "id": "GO:0004945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004945", "evidence": [ { "database": "UniProtKB", "id": "G5E6F7", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6F7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 362, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6F7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6F7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6F7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 317, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6G0-1", "uniprot_ac": "G5E6G0", "uniprot_id": "G5E6G0_BOVIN", "mass": { "chemical_mass": 31659.0, "monoisotopic_mass": 31659.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "G5E6G0", "database": "UniProtKB", "url": 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"url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038418", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCTIVTE", "url": "https://omabrowser.org/oma/group/SCTIVTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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"MDEENCTAVTDFILLGFSDAPELRLFLFLLFLSIYGVTVWGNLGMIALIQMIANILKEDKVISFLELTVQFYLFCTSVVTEVILLAVMAYDRFVAICDPLLYMVTMSRNLCMELVSCCYLNGTVCSVIHLCLDLQIPSYRSNVINHFFCDIPLLLSLACSDVTVNQLVLYTVATFSEIITSVIILISYLFFLITILRIHSAEERCKAFYTCASHLAAIAVLQGTILIIYCWPHSGNSMDIDRVATVFYTVVIPILNPLIYSLRNKDVKEALRKVVSSKIFS", "length": 281, "header": "tr|G5E6G0-1|G5E6G0_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G5E6G0-1" }, "locus": { "chromosome": "28", "start_pos": 97367, "end_pos": 96434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055903.3", "url": "https://www.ensembl.org/id/ENSBTAT00000055903.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051917.3", "url": "https://www.ensembl.org/id/ENSBTAP00000051917.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { 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"phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"id": "G5E6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6G2/entry#names_and_taxonomy" } ] }, { "name": "heme-binding protein 1-like", "type": "synonym", "evidence": [ { "id": "XP_059743277", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059743277" } ] } ], "function": [ { "annotation": "May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.", "evidence": [ { "database": "UniProtKB", "id": "G5E6G2", "url": "https://www.uniprot.org/uniprotkb/G5E6G2#function" }, { "database": "UniProtKB", "id": "ARBA00037673", "url": "https://www.uniprot.org/uniprotkb/ARBA00037673#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6G2", "url": "https://www.uniprot.org/uniprotkb/G5E6G2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC101905801", "url": "https://www.uniprot.org/uniprotkb/G5E6G2", "locus": {} } ], "crossref": [ { "id": "G5E6G2", "url": "https://alphafold.ebi.ac.uk/entry/G5E6G2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016876", "url": 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"tr|G5E6G2-1|G5E6G2_BOVIN Isoform 1 of Heme-binding protein 1 OS=Bos taurus OX=9913 GN=LOC101905801 PE=3 SV=2 CANONICAL=G5E6G2-1" }, "isoforms": [ { "isoform_ac": "G5E6G2-1", "url": "https://www.uniprot.org/uniprotkb/G5E6G2/entry", "sequence": { "sequence": "MLGMIKNSLFGSVETWPWQVLSKGSKGDVFYEERACEGGKFATVEVTDKPVDEALREAMPKVMKYVGGSNDKGLGMGMTVPISFAVFPSDDGDLQKKLKVWFWIPNKFQSDPPAPSDDSIKIEDREGITVYSTQFGGYAKAADYAAQAIQLRSALESTAKYQTDFYFCTGYDPPMKPYGHRNEVWLVKSSE", "length": 191, "header": "tr|G5E6G2-1|G5E6G2_BOVIN Isoform 1 of Heme-binding protein 1 OS=Bos taurus OX=9913 GN=LOC101905801 PE=3 SV=2 CANONICAL=G5E6G2-1" }, "locus": { "chromosome": "5", "start_pos": 100277634, "end_pos": 100277062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022449.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022449.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052078.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052078.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101905801", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101905801", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E6G2", "url": "https://www.uniprot.org/uniprotkb/G5E6G2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "G5E6G2", "url": "https://www.uniprot.org/uniprotkb/G5E6G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6G2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 191, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6G2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6G2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6G3-1", "uniprot_ac": "G5E6G3", "uniprot_id": "G5E6G3_BOVIN", "mass": { "chemical_mass": 34766.0, "monoisotopic_mass": 34766.0 }, "refseq": { "ac": "NP_001377206", "name": "olfactory receptor family 6 subfamily B member 2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377206" }, "gene_names": [ { "name": "OR6B2", "type": "recommended", "evidence": [ { "id": "G5E6G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6G3" } ] }, { "name": "OR6B2", "type": "synonym", "evidence": [ { "id": "NP_001377206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377206" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E6G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6G3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 6B2", "type": "synonym", "evidence": [ { "id": "NP_001377206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377206" } ] }, { "name": "olfactory receptor family 6 subfamily B member 2", "type": "synonym", "evidence": [ { "id": "NP_001377206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377206" } ] } ], "function": [ { "annotation": "INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. This record has been curated by NCBI staff in collaboration with Tsviya Olender. The reference sequence was derived from NKLS02000003.1. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"MATSNSSTIVSSTFYLTGIPGYEEFHHWISIPFCFLYLVGITGNCMILHIVRTDPRLHEPMYYFLAMLSLTDMAMSLPTMMSLFRVLWSISREIQFNICVVQMFLIHTFSFTESSVLLAMALDRYVAICHPLRYATILTPKLIAKIGTAALLRSSILIIPLIARLAFFPFCGSHVLSHSYCLHQDMIRLACADIRFNVIYGLVLITLLWGMDSLGIFVSYVLILHSVLKIASREGRLKALNTCASHICAVLILYVPMIGLSIVHRFAKHSSPLIHIFMAHIYLLVPPVLNPIIYSVKTKQIREGILHLLCSPKISSITM", "length": 319 }, "evidence": [ { "id": "G5E6H0", "url": "https://omabrowser.org/oma/group/G5E6H0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G5E6H0", "url": "https://www.uniprot.org/uniprotkb/G5E6H0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G5E6H0", "url": "https://www.uniprot.org/uniprotkb/G5E6H0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E6H0", "url": "https://www.uniprot.org/uniprotkb/G5E6H0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "G5E6H0", "url": "https://www.uniprot.org/uniprotkb/G5E6H0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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24292604, "end_pos": 24269587, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047287", "url": "https://www.ensembl.org/id/ENSBTAG00000047287" } ] } } ], "crossref": [ { "id": "G5E6I5", "url": "https://alphafold.ebi.ac.uk/entry/G5E6I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047287", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047287", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "537028", "url": "https://www.ncbi.nlm.nih.gov/gene/537028", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011037", "database": "InterPro", 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"MGAAGSSALARPGLPAPPGPRWLGVAALGLAAVALGAVAWRRARSRRRGRLQQVGTVSELWIYPIKSCKGASVDAAECTALGLRSGHLRDRFWLVINKEGNMVTARQEPRLVLISLTCEGDTLTLSAAYTKDLQLPVKTPTTNVVHRCRVHGLEIEGRDCGEAAAQWITNFLKTQPYRLVHFEPHMQPRNSHQVEDAFSPTDQIPYSDASPFLILSEASLADLNSRLEKKVKIANFRPNIVISGCGVYAEDSWNELLIGDVELKRVMACSRCILTTVDPDTGVMSRKEPLETLKSYRLCDPSERKLYGKSPLFGQYFVLENPGTIHVGDPVYLLGQE", "length": 337, "header": "tr|G5E6I5-1|G5E6I5_BOVIN Isoform 1 of Mitochondrial amidoxime reducing component 1 OS=Bos taurus OX=9913 GN=MTARC1 PE=4 SV=2 CANONICAL=G5E6I5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P399-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P399/entry", "sequence": { "sequence": "MVTARQEPRLVLISLTCEGDTLTLSAAYTKDLQLPVKTPTTNVVHRCRVHGLEIEGRDCGEAAAQWITNFLKTQPYRLVHFEPHMQPRNSHQVEDAFSPTDQIPYSDASPFLILSEASLADLNSRLEKKVKIANFRPNIVISGCGVYAEDSWNELLIGDVELKRVMACSRCILTTVDPDTGVMSRKEPLETLKSYRLCDPSERKLYGKSPLFGQYFVLENPGTIHVGDPVYLLGQE", "length": 236, "header": "tr|A0ABI0P399-1|A0ABI0P399_BOVIN Computationally mapped isoform of Mitochondrial amidoxime reducing component 1 OS=Bos taurus OX=9913 GN=MTARC1 PE=4 SV=1 CANONICAL=G5E6I5-1" }, "locus": { "chromosome": "16", "start_pos": 24291600, "end_pos": 24273733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143275.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143275.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106070.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106070.1" } ] } }, { "isoform_ac": "G5E6I5-1", "url": "https://www.uniprot.org/uniprotkb/G5E6I5/entry", "sequence": { "sequence": "MGAAGSSALARPGLPAPPGPRWLGVAALGLAAVALGAVAWRRARSRRRGRLQQVGTVSELWIYPIKSCKGASVDAAECTALGLRSGHLRDRFWLVINKEGNMVTARQEPRLVLISLTCEGDTLTLSAAYTKDLQLPVKTPTTNVVHRCRVHGLEIEGRDCGEAAAQWITNFLKTQPYRLVHFEPHMQPRNSHQVEDAFSPTDQIPYSDASPFLILSEASLADLNSRLEKKVKIANFRPNIVISGCGVYAEDSWNELLIGDVELKRVMACSRCILTTVDPDTGVMSRKEPLETLKSYRLCDPSERKLYGKSPLFGQYFVLENPGTIHVGDPVYLLGQE", "length": 337, "header": "tr|G5E6I5-1|G5E6I5_BOVIN Isoform 1 of Mitochondrial amidoxime reducing component 1 OS=Bos taurus OX=9913 GN=MTARC1 PE=4 SV=2 CANONICAL=G5E6I5-1" }, "locus": { "chromosome": "16", "start_pos": 24291600, "end_pos": 24269786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061104.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061104.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053211.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053211.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:537028", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537028", "resource": "KEGG Pathway" }, { "id": "R-BTA-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B6R1-1", "protein_name": "Mitochondrial amidoxime reducing component 1", "gene_name": "MTARC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGAAGSSPLVRLRLRLPALLRPGLGLAALGLAAAALGAVAWSRARPRRRRRRRRLQQVGTVSQLWIYPVKSCKGVPVSEAECTALGLRRGHLRDRFWLVINKEGNMVTARQEPRLVLISPTCEGDTLTLSAAYTEDLQLPIKAPTTNAVHNCRVQGLQIQGRDCGEAAAQWITSFLKTQPYRLVHFEPHMSPRNSHQIEHLFRPTDQVAYSDASPFLILSEASLADLNSRLEKKVKAANFRPNIVISGCDAYAEDSWDEILIGDVELKRVMACYRCVLTTVDPDTGIMSRKEPLETLRSYRLCDPSEEKLYGKSPFFGQYFVLENPGTIQVGDPVYLLGQE", "length": 341 }, "evidence": [ { "id": "G5E6I5", "url": "https://omabrowser.org/oma/group/G5E6I5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z900-1", "protein_name": "Mitochondrial amidoxime reducing component 1", "gene_name": "Mtarc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSARTWALALLGFSATRVSRQPGSTWVCVAALGLAAVTLGTVAWRRARPRRRRRLQQVGTVAQLWIYPIKSCKGVSVTEAECTAMGLRCGHLRDRFWLVVNEEGNMVTARQEPRLVQISLTCEDDNLTLSAAYTKDLLLPITPPATNPLLQCRVHGLEVQGRDCGEDAAQWISGFLKTQRCRLVHFEPHMHPRSSQKMRASFRPTDQVAYADASPFLVLSEASLEDLNSRLERRVKAANFRPNIVISGCGIYAEDSWNEVLIGDVELKRVMPCTRCLLTTVDPDTGIMDKKEPLETLKSYRLCEPSEQALCGKLPTFGQYFALENPGTIKVGDPVYLLS", "length": 339 }, "evidence": [ { "id": "G5E6I5", "url": "https://omabrowser.org/oma/group/G5E6I5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54JB6-1", "protein_name": "Molybdenum cofactor sulfurase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNFIDFVQANIKYFIGAGILALNIISFYNYYSNKNNANNNNNNNNINNNNNNTLGDSSPRDHPFRIKKIIIYPIKSCKGIEVRSCKIDKYGFENDRRFMLIHQGRFMSQRTTPKMALIEPDISEDGQYLIINAKGQNEIRVKIGDTNDKEIIKVGIWKDTVDVVDCGDQVSEWLTKFLDTEARLVTIAPGEYHRRVPEDYVDHIIEEPTEIDRDNYQFALCDTSQVMILSESSIDDINMHIDAIRKEKKEKPRDPVTFSNFRPNILVSGYDCSPFEEDRWEQIRISGLLLSRVAFTPRCKLTTVQPETGILDPYGDNEPLRTMETYRKFNGKLLFGALFVHSNPIADGEELFVGNIIDVLKINNKPYEK", "length": 371 }, "evidence": [ { "id": "G5E6I5", "url": "https://omabrowser.org/oma/group/G5E6I5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5VT66-1", "protein_name": "Mitochondrial amidoxime-reducing component 1", "gene_name": "MTARC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAAGSSALARFVLLAQSRPGWLGVAALGLTAVALGAVAWRRAWPTRRRRLLQQVGTVAQLWIYPVKSCKGVPVSEAECTAMGLRSGNLRDRFWLVINQEGNMVTARQEPRLVLISLTCDGDTLTLSAAYTKDLLLPIKTPTTNAVHKCRVHGLEIEGRDCGEATAQWITSFLKSQPYRLVHFEPHMRPRRPHQIADLFRPKDQIAYSDTSPFLILSEASLADLNSRLEKKVKATNFRPNIVISGCDVYAEDSWDELLIGDVELKRVMACSRCILTTVDPDTGVMSRKEPLETLKSYRQCDPSERKLYGKSPLFGQYFVLENPGTIKVGDPVYLLGQ", "length": 337 }, "evidence": [ { "id": "G5E6I5", "url": "https://omabrowser.org/oma/group/G5E6I5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FYH8-1", "protein_name": "Molybdenum cofactor sulfurase family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MENTLSPLLSPSPASEVAARVSSLFVYPIKSCRGISLSQAALTPTGFRWDRNWLIVNSKGRGLTQRVEPKLSLIEVEMPKHAFGEDWEPEKSSNMVVRAPGMDALKVSLAKPDKIADGVSVWEWSGSALDEGEEASQWFTNFVGKPCRLVRFNSAYETRPVDPNYAPGHIAMFSDMYPFLLISQGSLDSLNKLLKEPVPINRFRPNIFVDGCEPFAEDLWTEILINGFTFHGVKLCSRCKVPTISQETGIGGQEPIETLRTFRSDKVLQPKSKPHGKIYFGQNMVWKDGFGDGIGKTIEIGDSVVVLRKLSSPAEAAT", "length": 318 }, "evidence": [ { "id": "G5E6I5", "url": "https://omabrowser.org/oma/group/G5E6I5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "molybdenum ion binding", "id": "GO:0030151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030151", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "nitrate reductase activity", "id": "GO:0008940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008940", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "molybdopterin cofactor binding", "id": "GO:0043546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043546", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "nitrite reductase (NO-forming) activity", "id": "GO:0050421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050421", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "nitric-oxide synthase complex", "id": "GO:1903958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903958", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nitric oxide biosynthetic process", "id": "GO:0006809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006809", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "nitrate metabolic process", "id": "GO:0042126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042126", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" }, { "name": "cellular detoxification of nitrogen compound", "id": "GO:0070458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070458", "evidence": [ { "database": "UniProtKB", "id": "G5E6I5", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6I5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 337, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6I5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6I5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6I5" }, { "id": "PS51340", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51340" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MOSC", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 334, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6I7-1", "uniprot_ac": "G5E6I7", "uniprot_id": "G5E6I7_BOVIN", "mass": { "chemical_mass": 20621.0, "monoisotopic_mass": 20621.0 }, "refseq": { "ac": "XP_005225330", "name": "class A basic helix-loop-helix protein 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225330" }, "gene_names": [ { "name": "BHLHA15", "type": "recommended", "evidence": [ { "id": "G5E6I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ] }, { "name": "BHLHA15", "type": "synonym", "evidence": [ { "id": "XP_005225330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225330" } ] } ], "protein_names": [ { "name": "Class A basic helix-loop-helix protein 15", "type": "recommended", "evidence": [ { "id": "G5E6I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6I7/entry#names_and_taxonomy" } ] }, { "name": "Class B basic helix-loop-helix protein 8", "type": "synonym", "evidence": [ { "id": "G5E6I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6I7/entry#names_and_taxonomy" } ] }, { "name": "Muscle, intestine and stomach expression 1", "type": "synonym", "evidence": [ { "id": "G5E6I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6I7/entry#names_and_taxonomy" } ] }, { "name": "class A basic helix-loop-helix protein 15", "type": "synonym", "evidence": [ { "id": "XP_005225330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225330" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BHLHA15", "url": "https://www.uniprot.org/uniprotkb/G5E6I7", "locus": { "chromosome": "25", "start_pos": 37789599, "end_pos": 37798384, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046010", "url": "https://www.ensembl.org/id/ENSBTAG00000046010" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046010", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046010", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19711", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19711", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100848337", "url": "https://www.ncbi.nlm.nih.gov/gene/100848337", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100848337", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848337", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRYSTQI", "url": "https://omabrowser.org/oma/group/HRYSTQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6I7", "url": "https://www.orthodb.org/?gene=G5E6I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19290:SF160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19290:SF160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005225330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6I7-1", "url": "https://www.uniprot.org/uniprotkb/G5E6I7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTKSRPPRRRAPPQDPEATPGERTPDRPPPGSGGPDATKALRSRTARAQGARAEGGRRRPGPGGRRESSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSGRLPGLDGPGPKLYQHYQQQQQQAAGGTLVAAEAPPEGHLQKYSTQIHSFREGS", "length": 187, "header": "tr|G5E6I7-1|G5E6I7_BOVIN Isoform 1 of Class A basic helix-loop-helix protein 15 OS=Bos taurus OX=9913 GN=BHLHA15 PE=4 SV=1 CANONICAL=G5E6I7-1" }, "isoforms": [ { "isoform_ac": "G5E6I7-1", "url": "https://www.uniprot.org/uniprotkb/G5E6I7/entry", "sequence": { "sequence": "MKTKSRPPRRRAPPQDPEATPGERTPDRPPPGSGGPDATKALRSRTARAQGARAEGGRRRPGPGGRRESSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSGRLPGLDGPGPKLYQHYQQQQQQAAGGTLVAAEAPPEGHLQKYSTQIHSFREGS", "length": 187, "header": "tr|G5E6I7-1|G5E6I7_BOVIN Isoform 1 of Class A basic helix-loop-helix protein 15 OS=Bos taurus OX=9913 GN=BHLHA15 PE=4 SV=1 CANONICAL=G5E6I7-1" }, "locus": { "chromosome": "25", "start_pos": 37789622, "end_pos": 37789599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000062953.3", "url": "https://www.ensembl.org/id/ENSBTAT00000062953.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055623.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055623.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 20, "start_aa": "Thr", "end_pos": 20, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr20", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100848337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848337", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B7J3-1", "protein_name": "Class A basic helix-loop-helix protein 15", "gene_name": "BHLHA15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKTKNRPPRRRAPPQDPEVTQGERTPETLQPGSGPEPAKALRGRTARVQTARAEGGRRRPGPVGRRESSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSGRLPGLDGPGPKLYQHYQQQQVAGGALGASEAEPEGHLQKYSTQIHSFREGS", "length": 184 }, "evidence": [ { "id": "G5E6I7", "url": "https://omabrowser.org/oma/group/G5E6I7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IC79-1", "protein_name": "Class A basic helix-loop-helix protein 15", "gene_name": "Bhlha15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKTKNRPPRRRTPMQDTEATPGEQTPDRPQSGSGGSELTKGLRSRTARAGGARAEVNRRRQGSGSRRENSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEGPSPAPGPKLYQHYHHQQQQQQQQQQVAGATLGATEDQPQGHLQRYSTQIHSFREGS", "length": 197 }, "evidence": [ { "id": "G5E6I7", "url": "https://omabrowser.org/oma/group/G5E6I7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P70562-1", "protein_name": "Class A basic helix-loop-helix protein 15", "gene_name": "Bhlha15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTKNRPPRRRTPMQDAEATPGEQTPDRSQSGSGASEVTKGLRSRTARASGTRAEVSRRRQGSSSRRENSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEAPGPAPGPKLYQHYHHQQQQQQQQQQVAGAVLGVTEDQPQGHLQRYSTQIHSFREGS", "length": 197 }, "evidence": [ { "id": "G5E6I7", "url": "https://omabrowser.org/oma/group/G5E6I7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7RTS1-1", "protein_name": "Class A basic helix-loop-helix protein 15", "gene_name": "BHLHA15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKTKNRPPRRRAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRPGPSGPGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEGPGPKLYQHYQQQQQVAGGALGATEAQPQGHLQRYSTQIHSFREGT", "length": 189 }, "evidence": [ { "id": "G5E6I7", "url": "https://omabrowser.org/oma/group/G5E6I7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYC3-1", "protein_name": "Class A basic helix-loop-helix protein 15", "gene_name": "Bhlha15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTKNRPPRRRTPMQDTEATPGEQTPDRPQSGSGGSELTKGLRSRTARASGGRGEVSRRRQGSGGRRENSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEAPGPAPGPKLYQHYHHQQQQQQQQQQVAGAMLGVTEDQPQGHLQRYSTQIHSFREGS", "length": 197 }, "evidence": [ { "id": "G5E6I7", "url": "https://omabrowser.org/oma/group/G5E6I7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "negative regulation of myotube differentiation", "id": "GO:0010832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010832", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "G5E6I7", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6I7" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 124, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 20 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6J3-1", "uniprot_ac": "G5E6J3", "uniprot_id": "G5E6J3_BOVIN", "mass": { "chemical_mass": 91834.0, "monoisotopic_mass": 91834.0 }, "refseq": { "ac": "XP_024850868", "name": "mediator of RNA polymerase II transcription subunit 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850868" }, "gene_names": [ { "name": "MED16", "type": "recommended", "evidence": [ { "id": "G5E6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ] }, { "name": "MED16", "type": "synonym", "evidence": [ { "id": "XP_024850868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850868" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 16", "type": "recommended", "evidence": [ { "id": "G5E6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6J3/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 16", "type": "synonym", "evidence": [ { "id": "G5E6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6J3/entry#names_and_taxonomy" } ] }, { "name": "mediator of RNA polymerase II transcription subunit 16", "type": "synonym", "evidence": [ { "id": "XP_024850868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850868" } ] } ], "function": [ { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LYI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI2#function" }, { "database": "UniProtKB", "id": "RU364149", "url": "https://www.uniprot.org/uniprotkb/RU364149#function" }, { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3#function" }, { "database": "UniProtKB", "id": "ARBA00025687", "url": "https://www.uniprot.org/uniprotkb/ARBA00025687#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MED16", "url": "https://www.uniprot.org/uniprotkb/G5E6J3", "locus": { "chromosome": "7", "start_pos": 43423510, "end_pos": 43436521, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047217", "url": "https://www.ensembl.org/id/ENSBTAG00000047217" } ] } } ], "crossref": [ { "id": "G5E6J3", "url": "https://alphafold.ebi.ac.uk/entry/G5E6J3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047217", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047217", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100298629", "url": "https://www.ncbi.nlm.nih.gov/gene/100298629", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100298629", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100298629", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIWQPKE", "url": "https://omabrowser.org/oma/group/EIWQPKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6J3", "url": "https://www.orthodb.org/?gene=G5E6J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13224:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13224:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11635", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11635", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024850868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6J3-1", "url": "https://www.uniprot.org/uniprotkb/G5E6J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLAYICEWEKWPKSTHCPSGPLACTWSCRNLIAFTTDLRSDDQDLTRMIHILDTEHPWDVHSIRSEHSEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESPVGSVVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQLYKVCVSVVNEKCRIDTELLPSLFMRCTTDLSRRDRLPAITHLKFLARDMSEQVLLCASSQTSSVVECWSLRKEGLPVNNIFQQLSPAVGDKQPTILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAIFYSSAAPRPIDEPALKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGRLSMLRISPSMGHSLDVGLALRHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVEKLHEEYTRQKAELQQVLSTRILAMKASLCKLSPCTVTRVCDYHAKLFLIAISSTLKSLLRPHVLNTPDKSPGDRLTEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLASLPNQGSPLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPTSEPDEALVDECCLLPSQLLIPSLDWLPVSDGLVSRLQPKQPLRLHFGKAPALPGSSTGLQLDGLIRAPGQPKMDHLRRLHLGAYPTEACKACTRCGCVTMLKSPNKTTAVKQWEQRWIKNCLCGGLWWRMPLSYP", "length": 829, "header": "tr|G5E6J3-1|G5E6J3_BOVIN Isoform 1 of Mediator of RNA polymerase II transcription subunit 16 OS=Bos taurus OX=9913 GN=MED16 PE=3 SV=2 CANONICAL=G5E6J3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LYI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYI2/entry", "sequence": { "sequence": "MDLAYICEWEKWPKSTHCPSGPLACTWSCRNLIAFTTDLRSDDQGSRLLSADADGQIKCWSMADHLANSWESPVGSVVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQLYKVCVSVVNEKCRIDTELLPSLFMRCTTDLSRRDRLPAITHLKFLARDMSEQVLLCASSQTSSVVECWSLRKEGLPVNNIFQQLSPAVGDKQPTILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAIFYSSAAPRPIDEPALKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGRLSMLRISPSMGHSLDVGLALRHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVEKLHEEYTRQKAELQQVLSTRILAMKASLCKLSPCTVTRVCDYHAKLFLIAISSTLKSLLRPHVLNTPDKSPGDRLTEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLASLPNQGSPLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPTSEPDEALVDECCLLPSQLLIPSLDWLPVSDGLVSRLQPKQPLRLHFGKAPALPGSSTGLQLDGLIRAPGQPKMDHLRRLHLGAYPTEACKACTRCGCVTMLKSPNKTTAVKQWEQRWIKNCLCGGLWWRMPLSYP", "length": 793, "header": "tr|A0A3Q1LYI2-1|A0A3Q1LYI2_BOVIN Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 16 OS=Bos taurus OX=9913 GN=MED16 PE=3 SV=1 CANONICAL=G5E6J3-1" }, "locus": { "chromosome": "7", "start_pos": 43434983, "end_pos": 43423527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069911.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069911.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065829.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065829.2" } ] } }, { "isoform_ac": "G5E6J3-1", "url": "https://www.uniprot.org/uniprotkb/G5E6J3/entry", "sequence": { "sequence": "MDLAYICEWEKWPKSTHCPSGPLACTWSCRNLIAFTTDLRSDDQDLTRMIHILDTEHPWDVHSIRSEHSEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESPVGSVVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQLYKVCVSVVNEKCRIDTELLPSLFMRCTTDLSRRDRLPAITHLKFLARDMSEQVLLCASSQTSSVVECWSLRKEGLPVNNIFQQLSPAVGDKQPTILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAIFYSSAAPRPIDEPALKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGRLSMLRISPSMGHSLDVGLALRHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVEKLHEEYTRQKAELQQVLSTRILAMKASLCKLSPCTVTRVCDYHAKLFLIAISSTLKSLLRPHVLNTPDKSPGDRLTEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLASLPNQGSPLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPTSEPDEALVDECCLLPSQLLIPSLDWLPVSDGLVSRLQPKQPLRLHFGKAPALPGSSTGLQLDGLIRAPGQPKMDHLRRLHLGAYPTEACKACTRCGCVTMLKSPNKTTAVKQWEQRWIKNCLCGGLWWRMPLSYP", "length": 829, "header": "tr|G5E6J3-1|G5E6J3_BOVIN Isoform 1 of Mediator of RNA polymerase II transcription subunit 16 OS=Bos taurus OX=9913 GN=MED16 PE=3 SV=2 CANONICAL=G5E6J3-1" }, "locus": { "chromosome": "7", "start_pos": 43434983, "end_pos": 43423527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064681.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064681.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055629.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055629.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 694, "start_aa": "Thr", "end_pos": 694, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr694", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100298629", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100298629", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" }, { "id": "R-BTA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2K5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "gene_name": "Med16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMDLAYVCEWEKWAKSTYCPSLPLACAWSCRNLIAFTTDLRNDDQDLTHMIHILDTEHPWEVHSVSSGHSEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESSVGSQVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRKDRFPAITHLKFLARDMSEQVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFQDGSVHMVHRLSLQTMAVFYSSAPRSLDEPALKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHALEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTMARVCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSALRPGHSFLRDGASLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPASEPDEGLVDECCLLPSQLLVPSLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSSTSILQLDGLTRAPGQPKIDHLRRLHLGAYPTEECKACTRCGCVTMLKSPNKTTAVKQWEQRWIKNCLCGGLWRRVPLSCS", "length": 829 }, "evidence": [ { "id": "G5E6J3", "url": "https://omabrowser.org/oma/group/G5E6J3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F602-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "gene_name": "med16", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMDIAYVCEWEKRPKSNHCPSIPLVCAWSCRNLIAFTTDLKNEEDDKGLDNAFITNITTPVDLSHMIHIIDTDHPWDVYSINSGHNEIISCLEWDQSGSRLLSADGDGQIKCWGMTEHLVNSWECAQSSSVDGDPIVALSWLHNGVKLALHVEKSGSTNFGEKFSRVKFSPSLTLFGGKPMEGWLAVTVSGLVTVSLLKPNGTLLTASESLCRLRGRVALADIAFTGGGNIVVAATDGSSSSPVQFYKVCVSVVNEKCRIDTELLPSLFMRCTTDPLRRDKYPAVTHLKFLTRENSEQVLLCASSQMGSIVECWSLRKEGLPVNNIFQHRSPVVGEKQPMTLKWRILSTTNDLDRVSAVALPKLPISISNTDLKVASDTKFFPGLGLALAFHDGSIQILHRLSLQTVGMFYGSSGSSQRVGEEPAIKRQRAGGPMLHFKALQFSWTSLALVGIDNHGKLHMFRVSPSMGQMLDMNTLLRHLLFLLEYCMVTGYDWWDVLLHAQPGMVHNLLEKLHEEYMRQNQALQQVLSTRIVAVKASLCKLSSATAARACDFHAKLLLIAISSTLKSLLRPHVLNTPDKSPGDRLSEICAKNTDTDIDKVMINLKTEEFVLDGPPLQSLQQLIQWVGDFVLYLLANLPNQGSIVRPGFGFLRDGASLGMLREMLVMIRIWGLLKPGCLPIYTATSDNQDSMFLLFRLLTKLWLCSRDESHPQDPDETLIDECCLLPSQLLVPSMDWLPINDGVITKIQGKHQLRLQFGKPYTLPGVNPNAQVEIFRSPASQRVDHLRCLHLGISPTEDSKACTRCGCVTMLRSPNKTNATRQWEQRWIKNCLCGGLWRRIPSTLS", "length": 847 }, "evidence": [ { "id": "G5E6J3", "url": "https://omabrowser.org/oma/group/G5E6J3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PGF3-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "gene_name": "Med16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLAYVCEWEKWAKSTYCPSLPLACAWSCRNLIAFTTDLRNDDQDLTHMIHILDTEHPWEVHSVSSGHSEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESSVGSQVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRKDRFPAITHLKFLARDMSEQVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFQDGSVHMVHRLSLQTMAVFYSSAPRSLDEPALKRPRTTCPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHPLEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTVARVCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSPLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGAASEPDEGLVDECCLLPSQLLVPNLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSSTSTLQLDGLTRAPGQPKIDHLRRLHLGAYPTEECKACTRCGCVTMLKSPNKTTAVTQWEQRWIKNCLCGGLWRRVPLSCS", "length": 828 }, "evidence": [ { "id": "G5E6J3", "url": "https://omabrowser.org/oma/group/G5E6J3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2X0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "gene_name": "MED16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCDLRRPAAGGMMDLAYVCEWEKWSKSTHCPSVPLACAWSCRNLIAFTMDLRSDDQDLTRMIHILDTEHPWDLHSIPSEHHEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESSVGSLVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQFYKVCVSVVSEKCRIDTEILPSLFMRCTTDLNRKDKFPAITHLKFLARDMSEQVLLCASSQTSSIVECWSLRKEGLPVNNIFQQISPVVGDKQPTILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAVFYSSAAPRPVDEPAMKRPRTAGPAVHLKAMQLSWTSLALVGIDSHGKLSVLRLSPSMGHPLEVGLALRHLLFLLEYCMVTGYDWWDILLHVQPSMVQSLVEKLHEEYTRQTAALQQVLSTRILAMKASLCKLSPCTVTRVCDYHTKLFLIAISSTLKSLLRPHFLNTPDKSPGDRLTEICTKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLASLPNQGSLLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPASEPDEALVDECCLLPSQLLIPSLDWLPASDGLVSRLQPKQPLRLQFGRAPTLPGSAATLQLDGLARAPGQPKIDHLRRLHLGACPTEECKACTRCGCVTMLKSPNRTTAVKQWEQRWIKNCLAVEGRGPDACVTSRASEEAPAFVQLGPQSTHHSPRTPRSLDHLHPEDRP", "length": 877 }, "evidence": [ { "id": "G5E6J3", "url": "https://omabrowser.org/oma/group/G5E6J3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "G5E6J3", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6J3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 829, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6J3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6J3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" }, { "id": "PF20719", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit 16 C-terminal", "eco_id": "ECO_0000259", "start_pos": 761, "end_pos": 821, "start_aa": "Ala", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" }, { "id": "PF11635", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11635" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit Med16 N-terminal", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 399, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E6J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6J3" }, { "id": "PF20718", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20718" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 16 central helical bridge", "eco_id": "ECO_0000259", "start_pos": 465, "end_pos": 653, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 171, 694 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 799, "end_pos": 801 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], 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"MVRLALPNPGLEARIPSLGELERVEREESSSRPTWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSAIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSQCPLNANQTGYVDECARSSSVDYFWYRETLNVSTSIDDSGSVQWWILLALTCAWSVLYVCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELANPVTWLDAGAQVFYSFSLAFGGLISFSSYNPVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFRATERYDDCFSTNILTLINGFDLPEGNVTQENFAEMQRWCNASDPAAYARLKFQTCDMDAFLSQGVEGTGLAFIVFTEAITKMPVAPLWSVLFFVMLFCLGLSSMFGNMEGVVVPLQDLKVIPKKWPKELLTGLICLGMYLIAFIFTLNSGQYWLSLLDSYAGSIPLLVIAFFEMFSVVYVYGVDRFNRDIEFMIGHKPNIFWQVTWRVVSPLLMLAIFLFFFVIEVREELTYNIWDPAYEEFPKSKEIKYPGWVYAVVVLVAGVPCLVIPGFAIYKLIRNHFQRRGDQRALVSSLSAASVNGGLWS", "length": 634, "header": "tr|G5E6L1-1|G5E6L1_BOVIN Isoform 1 of Transporter OS=Bos taurus OX=9913 GN=SLC6A19 PE=3 SV=2 CANONICAL=G5E6L1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5Z8/entry", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSBTAT00000151363.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106674.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106674.1" } ] } }, { "isoform_ac": "G5E6L1-1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1/entry", "sequence": { "sequence": "MVRLALPNPGLEARIPSLGELERVEREESSSRPTWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSAIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSQCPLNANQTGYVDECARSSSVDYFWYRETLNVSTSIDDSGSVQWWILLALTCAWSVLYVCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELANPVTWLDAGAQVFYSFSLAFGGLISFSSYNPVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFRATERYDDCFSTNILTLINGFDLPEGNVTQENFAEMQRWCNASDPAAYARLKFQTCDMDAFLSQGVEGTGLAFIVFTEAITKMPVAPLWSVLFFVMLFCLGLSSMFGNMEGVVVPLQDLKVIPKKWPKELLTGLICLGMYLIAFIFTLNSGQYWLSLLDSYAGSIPLLVIAFFEMFSVVYVYGVDRFNRDIEFMIGHKPNIFWQVTWRVVSPLLMLAIFLFFFVIEVREELTYNIWDPAYEEFPKSKEIKYPGWVYAVVVLVAGVPCLVIPGFAIYKLIRNHFQRRGDQRALVSSLSAASVNGGLWS", "length": 634, "header": "tr|G5E6L1-1|G5E6L1_BOVIN Isoform 1 of Transporter OS=Bos taurus OX=9913 GN=SLC6A19 PE=3 SV=2 CANONICAL=G5E6L1-1" }, "locus": { "chromosome": "20", "start_pos": 71199065, "end_pos": 71184575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064818.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064818.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055648.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055648.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100337416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337416", "resource": "KEGG Pathway" }, { "id": "R-BTA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" }, { "id": "R-BTA-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LWZ8-1", "protein_name": "Transporter", "gene_name": "Slc6a19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRLVLPNPGLEDRIPSRDELEVIEKEEASSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSSIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNVNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCVIRGIETTGKAVYVTSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSIINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTSENFEAVQQWCNATNPEVYAQLKFQTCDMNSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNLIPKKWPKELMTGLICLGTYLIAFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKKLMYSVWDPNYEEFPKSQRVPYPNWVYAVVVIVAGVPCLTIPCFAIYKLIRNRCQKSGDHHGLVNALSTASVNGDLKY", "length": 634 }, "evidence": [ { "id": "G5E6L1", "url": "https://omabrowser.org/oma/group/G5E6L1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7EY30-1", "protein_name": "Transporter", "gene_name": "slc6a19a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLKLKLPNPGLEQRIPSHSELEKLELQEAGERPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRRGSVGVWRSINPYLLGVGIASMLVSFIVGMYYNTIIAWVMWYFFNSFQDPLPWSQCPINGSRTGFVSECERSSPVDYFWYRKTLNTTPHIEDSGGLQWWMVLSLLCAWTVLWVCCIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVSGIKFLFTPDVNELLDPQTWLDAGAQVFFSFSLAFGGLIAFSSYNSVHNNCEQDAVIISIINGMTSIYAAIVIYSIIGFRATERFDDCLNGNILSLLNAFDLPEGSIIEGNYTEAIQQLNISRPDIIQELQLKTCDMQTFLSQGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSTMFGSIEGVVVPLQDLDILPKNWPKEAYTALVCVVSFAFAIIFAQGSGEYWLALFDGFAVSIPLLIIAFCEMMAVSYVYGIDRFNDDIKFMIGHKPNIFWQATWRLISPLIVLVIFLFYFVTTVSKKLTYIAWDPESENFPTLSVLPYPGWISAIIFILAGIPVLVIPTVALVRLIRNRCCKKEETHATETPYSISDRVQMMEETEQNNPISTALH", "length": 647 }, "evidence": [ { "id": "G5E6L1", "url": "https://omabrowser.org/oma/group/G5E6L1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1NPI1-1", "protein_name": "Transporter", "gene_name": "SLC6A19", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVKLQLPNPGLEDRIPSHTELEVLEKEEADSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLILEGIPLLHLEFAIGQRLRRGSVGVWSSIHPTLKGVGIAAMCVSFLVSLYYNTIIAWVMWYFFNSFQEPLPWSTCPLIDNRTDYIEECAKSSPVDYFWYRETLNTSTSIEDSGTIQWWLLLCLTCAWGILYVCTIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVNGIVFLFTPNVAELANPVTWLDAGAQVFYSFSLAFGGLISFSSYNPVHNNCEKDAVIISVINGFTSIYAATVIYSIIGFRATERYDDCFDKNILTLINAFDLPEGNVTQDNFEQMQQLCNMTDPVTFASLNFETCDLKSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSILFFIMLFCLGLSSMFGNVEGVLVPLQDLKVVPPKWPKELITGIVCAGSYLIAFIFVLRSGNYWLALFDSFAGSIPLLIIAFCEMFSVVYIYGIDRFNKDIEFMIGHKPNIFWQVTWRVISPLIMLVIFLFYFVVKVNEELLYSVWNPKYEEFPKPQKIGYPGWVYAIIVIIAGVPSLIIPVFAIYKAIRNCCQKRRDRTGLISSISETSVNGNLKNSA", "length": 636 }, "evidence": [ { "id": "G5E6L1", "url": "https://omabrowser.org/oma/group/G5E6L1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q2A865-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT1", "gene_name": "Slc6a19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRLVLPNPGLEDRIPSLDELEVIEKEEASSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSSIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNQNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSIINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTAENFEAYQHWCNATNPEAYAQLTFQTCDINTFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKQLMYSVWDPDYEEFPKSQKVPYPDWVYAVVVIVAGVPCLTIPCFAIYKLIRNYCQKSGDQHGLVNALSTASVNGDLKN", "length": 634 }, "evidence": [ { "id": "G5E6L1", "url": "https://omabrowser.org/oma/group/G5E6L1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q695T7-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT1", "gene_name": "SLC6A19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRLVLPNPGLDARIPSLAELETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWSDCPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGDHQGLVSTLSTASMNGDLKY", "length": 634 }, "evidence": [ { "id": "G5E6L1", "url": "https://omabrowser.org/oma/group/G5E6L1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D687-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT1", "gene_name": "Slc6a19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRLVLPNPGLEERIPSLDELEVIEKEEAGSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLYLEFAIGQRLRKGSMGVWSSIHPALKGIGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNQNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCIIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTSENFEAYQQWCNATNPQAYAQLKFQTCDINSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSFAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKTLMYSIWDPNYEEFPKSQKIPYPNWVYAVVVTVAGVPCLSIPCFAIYKFIRNCCQKSDDHHGLVNTLSTASVNGDLKN", "length": 634 }, "evidence": [ { "id": "G5E6L1", "url": "https://omabrowser.org/oma/group/G5E6L1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" }, { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "neutral amino acid transport", "id": "GO:0015804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015804", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" }, { "name": "amino acid import across plasma membrane", "id": "GO:0089718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089718", "evidence": [ { "database": "UniProtKB", "id": "G5E6L1", "url": "https://www.uniprot.org/uniprotkb/G5E6L1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6L1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 634, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6L1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6L1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 368, "end_pos": 370 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "G5E6L3", "uniprot_id": "G5E6L3_BOVIN", "mass": { "chemical_mass": 35419.0, "monoisotopic_mass": 35419.0 }, "refseq": { "ac": "NP_001377321", "name": "olfactory receptor family 51 subfamily A member 7", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377321" }, "gene_names": [ { "name": "OR51A7", "type": "recommended", "evidence": [ { "id": "G5E6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6L3" } ] }, { "name": "OR51A7", "type": "synonym", "evidence": [ { "id": "NP_001377321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377321" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "G5E6L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6L3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 51 subfamily A member 7", "type": "synonym", "evidence": [ { "id": "NP_001377321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377321" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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"MWGGNETESTNFILLGFFPEFRYTTALVSIVLLIYMAAFIGNTLLVLLIWLDSRLHTPMYFLLSQLSLMDLTLTSSIIPKMVANFFSGWQSISFLACGTQIFFSLTVAIGECILITVMCFDRYVAICNPLRYPVIMSPRMCWQVAAMSWAGGALTSSGHTAFTLHFHICSPREIPHFFCEVMAVLRIVCEDISAYEKAVVVTSILVLLLPLSLILSSYILIFLAVLRMNSPEGRNKTLATCSSHLCVVGLYFGPGMCIYMRPGSAKTPKLNQGLFLFGTVLTPLLNPLAYSLRNKEVLCSLKKLMGRFQSTR", "length": 312, "header": "tr|G5E6M9-1|G5E6M9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2AV11 PE=3 SV=3 CANONICAL=G5E6M9-1" }, "locus": { "chromosome": "7", "start_pos": 42852380, "end_pos": 42851445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063797.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063797.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056373.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056373.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:785149", "name": "", "url": 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"pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6M9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6M9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6M9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6M9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled 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initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376964" }, "gene_names": [ { "name": "OR8D6", "type": "recommended", "evidence": [ { "id": "G5E6N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N0" } ] }, { "name": "OR8D2", "type": "synonym", "evidence": [ { "id": "NP_001376964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376964" } ] }, { "name": "OR8D6", "type": "synonym", "evidence": [ { "id": "NP_001376964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376964" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 8 subfamily D member 6", "type": "synonym", "evidence": [ { "id": "G5E6N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 8 subfamily D member 6", "type": "synonym", "evidence": [ { "id": "NP_001376964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376964" } ] }, { "name": "olfactory receptor, family 8, subfamily D, member 2", "type": "synonym", "evidence": [ { "id": "NP_001376964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376964" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376964" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E6N0", "url": "https://www.uniprot.org/uniprotkb/G5E6N0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6N0", "url": "https://www.uniprot.org/uniprotkb/G5E6N0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8D6", "url": "https://www.uniprot.org/uniprotkb/G5E6N0", "locus": { "chromosome": "29", "start_pos": 27307273, "end_pos": 27306332, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017495", "url": "https://www.ensembl.org/id/ENSBTAG00000017495" } ] } } ], "crossref": [ { "id": "G5E6N0", "url": "https://alphafold.ebi.ac.uk/entry/G5E6N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "521903", "url": "https://www.ncbi.nlm.nih.gov/gene/521903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521903", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LIYMVCM", "url": "https://omabrowser.org/oma/group/LIYMVCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6N0", "url": "https://www.orthodb.org/?gene=G5E6N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376964", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E6N0", "url": "https://www.uniprot.org/uniprotkb/G5E6N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6N0-1", "url": "https://www.uniprot.org/uniprotkb/G5E6N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTGNHSSVTEFILEGLTDQPGLQLPLFFLFLMIYMVSMVNNLGLVILIRISSQLHVPMYYFLSNLSFIGLCYSSVIIPKMLVNFMSEKNFTSFPECMVQLFFFCFFGINDSYMLTAMAYDRYVAICNPLLYTVTMSHRVCFLLVTGVYIMGAVGASIHTSFISSRSFCGTNVIHHYFCDILPLLNISCSRDYTKELSVMILVGFNVFACAVAIFISYAFILPSILRIHSAEDRSKAFSTCSSHLAAVGVFYGSIIFMYFKPSTSDTEQEKVASVFYTTVIPMLNPLIYSLRNKDVKESIKKVLKGGIVPRSV", "length": 313, "header": "tr|G5E6N0-1|G5E6N0_BOVIN Isoform 1 of Olfactory receptor family 8 subfamily D member 6 OS=Bos taurus OX=9913 GN=OR8D6 PE=3 SV=2 CANONICAL=G5E6N0-1" }, "isoforms": [ { "isoform_ac": "G5E6N0-1", "url": "https://www.uniprot.org/uniprotkb/G5E6N0/entry", "sequence": { "sequence": "MDTGNHSSVTEFILEGLTDQPGLQLPLFFLFLMIYMVSMVNNLGLVILIRISSQLHVPMYYFLSNLSFIGLCYSSVIIPKMLVNFMSEKNFTSFPECMVQLFFFCFFGINDSYMLTAMAYDRYVAICNPLLYTVTMSHRVCFLLVTGVYIMGAVGASIHTSFISSRSFCGTNVIHHYFCDILPLLNISCSRDYTKELSVMILVGFNVFACAVAIFISYAFILPSILRIHSAEDRSKAFSTCSSHLAAVGVFYGSIIFMYFKPSTSDTEQEKVASVFYTTVIPMLNPLIYSLRNKDVKESIKKVLKGGIVPRSV", "length": 313, "header": "tr|G5E6N0-1|G5E6N0_BOVIN Isoform 1 of Olfactory receptor family 8 subfamily D member 6 OS=Bos taurus OX=9913 GN=OR8D6 PE=3 SV=2 CANONICAL=G5E6N0-1" }, "locus": { "chromosome": "29", "start_pos": 27307270, "end_pos": 27306332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023280.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023280.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056374.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056374.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521903", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521903", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2E7-1", "protein_name": "Olfactory receptor family 8 subfamily D member 6", "gene_name": "Or8d6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPGNHSETSLFVLEGLTDKPELQIPLFSLFLLIYVVSMAGNLGLVFLIRISSQLHTPMYYFLSNLSFIDFCYSSVIIPKMLVNFVSEKNFTSFPECMAQLYLFSFFGIDDSFMLTAMAYDRYVAICNPLLYNVTMSHRVCMLLSTAVYIMGTFGATVHTSYISSRSFCGTSVIHHYFCDILPLLNIACSRDYTKEFWVMIIVGFNVFASVFAIFISYAFILASILRIRSAEGRSKAFSTCSSHLAAVGVFYGSIIFMYFKPSTSDTTQEKVASVFYTTVIPMLNPLIYSLRNKDVKEAIKKAVNGGLFS", "length": 310 }, "evidence": [ { "id": "G5E6N0", "url": "https://omabrowser.org/oma/group/G5E6N0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S806-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6N3-1", "uniprot_ac": "G5E6N3", "uniprot_id": "G5E6N3_BOVIN", "mass": { "chemical_mass": 44684.0, "monoisotopic_mass": 44684.0 }, "refseq": { "ac": "XP_024845773", "name": "terminal nucleotidyltransferase 5C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024845773" }, "gene_names": [ { "name": "TENT5C", "type": "recommended", "evidence": [ { "id": "G5E6N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N3" } ] }, { "name": "TENT5C", "type": "synonym", "evidence": [ { "id": "XP_024845773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024845773" } ] } ], "protein_names": [ { "name": "Terminal nucleotidyltransferase 5C", "type": "recommended", "evidence": [ { "id": "G5E6N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N3/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.19", "type": "synonym", "evidence": [ { "id": "G5E6N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N3/entry#names_and_taxonomy" } ] }, { "name": "terminal nucleotidyltransferase 5C", "type": "synonym", "evidence": [ { "id": "XP_024845773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024845773" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6N3", "url": "https://www.uniprot.org/uniprotkb/G5E6N3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TENT5C", "url": "https://www.uniprot.org/uniprotkb/G5E6N3", "locus": { "chromosome": "3", "start_pos": 25583105, "end_pos": 25612405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000055713", "url": "https://www.ensembl.org/id/ENSBTAG00000055713" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046509", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046509", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517961", "url": "https://www.ncbi.nlm.nih.gov/gene/517961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517961", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWDQVSR", "url": "https://omabrowser.org/oma/group/TWDQVSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6N3", "url": "https://www.orthodb.org/?gene=G5E6N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12974:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12974:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024845773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024845773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11332", "url": "https://www.rhea-db.org/rhea/11332", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G5E6N3", "url": "https://www.uniprot.org/uniprotkb/G5E6N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6N3-1", "url": "https://www.uniprot.org/uniprotkb/G5E6N3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEESSSTRDCVSFSVLTWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRGRLEEAGIKVQDIRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPTTLKEAYVQKLVKVCTDADRWSLISLSNKNGRNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSGHPLSEHLHPTVIGESVYGDFEEALDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPTDQDEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMTLRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPNASTVTCYYQPAPYVSDGNFSNYYAAHPPLTYSQPYPTWLPCN", "length": 391, "header": "tr|G5E6N3-1|G5E6N3_BOVIN Isoform 1 of Terminal nucleotidyltransferase 5C OS=Bos taurus OX=9913 GN=TENT5C PE=3 SV=2 CANONICAL=G5E6N3-1" }, "isoforms": [ { "isoform_ac": "G5E6N3-1", "url": "https://www.uniprot.org/uniprotkb/G5E6N3/entry", "sequence": { "sequence": "MAEESSSTRDCVSFSVLTWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRGRLEEAGIKVQDIRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPTTLKEAYVQKLVKVCTDADRWSLISLSNKNGRNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSGHPLSEHLHPTVIGESVYGDFEEALDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPTDQDEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMTLRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPNASTVTCYYQPAPYVSDGNFSNYYAAHPPLTYSQPYPTWLPCN", "length": 391, "header": "tr|G5E6N3-1|G5E6N3_BOVIN Isoform 1 of Terminal nucleotidyltransferase 5C OS=Bos taurus OX=9913 GN=TENT5C PE=3 SV=2 CANONICAL=G5E6N3-1" }, "locus": { "chromosome": "3", "start_pos": 25593796, "end_pos": 25592624, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122450.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122450.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079930.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079930.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:517961", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517961", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AN43-1", "protein_name": "Terminal nucleotidyltransferase 5C", "gene_name": "TENT5C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEESSSARDCVSFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSQLEEAGIKVQDIRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVSKLKISPVTLKEAYVQKLVKVCTDTDRWSLISLSNKNGRNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSSHPISEHLHPTVIGESVYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPTDQDEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMTLRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPNATTVTCYYQPAPYVSDGNFNNYYVAHPPLPYSQPYPTWLPCN", "length": 391 }, "evidence": [ { "id": "G5E6N3", "url": "https://omabrowser.org/oma/group/G5E6N3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H912-1", "protein_name": "Terminal nucleotidyltransferase 5C", "gene_name": "Tent5c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEEGSSTRDCESISVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVQDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKVCTDADRWSLISLSNKNGRNVELKFVDSIRRQFEFSVDSFQIILDSLLLFYDCSSNPISEHFHPTVIGESVYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPADQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPSATNVTCYYQPAPYVSDGNFNNYYIAHPPVTYSQPYPTWLPCN", "length": 391 }, "evidence": [ { "id": "G5E6N3", "url": "https://omabrowser.org/oma/group/G5E6N3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5SSF7-1", "protein_name": "Terminal nucleotidyltransferase 5C", "gene_name": "Tent5c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEEGSSTKDSESFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRGRLEEAGINVQDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKVCTDTDRWSLISLSNKNGRNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSGNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPADQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFSDEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPSATNVTCYYQPAPYVSDGNFNNYYIAHPPITYSQPYPTWLPCN", "length": 391 }, "evidence": [ { "id": "G5E6N3", "url": "https://omabrowser.org/oma/group/G5E6N3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5VWP2-1", "protein_name": "Terminal nucleotidyltransferase 5C", "gene_name": "TENT5C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEESSCTRDCMSFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKVCTDTDRWSLISLSNKNGKNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSNNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPTDQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPSATNVTCYYQPAPYVSDGNFSNYYVAHPPVTYSQPYPTWLPCN", "length": 391 }, "evidence": [ { "id": "G5E6N3", "url": "https://omabrowser.org/oma/group/G5E6N3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5XIV0-1", "protein_name": "Terminal nucleotidyltransferase 5C", "gene_name": "Tent5c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADEGSSTKDSESFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVQDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKVCTDTDRWSLISLSNKNGRNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSSNPVSEHFHPTVVGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPADQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFADEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPSATNVTCYYQPAPYVSDGNFNNYYIAHPPVTYSQPYPTWLPCN", "length": 391 }, "evidence": [ { "id": "G5E6N3", "url": "https://omabrowser.org/oma/group/G5E6N3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5ZL95-1", "protein_name": "Terminal nucleotidyltransferase 5C", "gene_name": "TENT5C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASKGSNTDCMSCSVLNWEQVSRLHEVLTEVVPIHGRGNFPTLKITLKDIVQTVRSRLNEAGIAVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFQVSLPSEAEFQLVRDVVLRSLLNFLPEGVSKLKISPVTLKEAYIQKLVKVSTESDRWSLISLSNKHGRNVELKFVDCIRRQFEFSVDSFQIILDSLLFYYDYSENPMSEHFHPTVIGESMYGDFEAAFDHLQNKLIATKNPEEIRGGGLLKYSNLLVRDFRPMDKDEIKTLERYMCSRFFIDFPDILDQQRKLETYLQNHFSKEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALKVLAEQNIIPNATTVTCYYQPAPYVSDVNFSNYYLANPPVPYSQSYPTWLPCN", "length": 390 }, "evidence": [ { "id": "G5E6N3", "url": "https://omabrowser.org/oma/group/G5E6N3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G5E6N3", "url": "https://www.uniprot.org/uniprotkb/G5E6N3" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "G5E6N3", "url": "https://www.uniprot.org/uniprotkb/G5E6N3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E6N3", "url": "https://www.uniprot.org/uniprotkb/G5E6N3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E6N3", "url": "https://www.uniprot.org/uniprotkb/G5E6N3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "G5E6N3", "url": "https://www.uniprot.org/uniprotkb/G5E6N3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA 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"MDSESHIAVRWVVAPARCGRRAAQSARLFCSSEGRAVGRGLRYAASVRGSTVVTRLVAFLVATPPAGRTRPASSATPIPLGLVGAALSSVILYTRKLAGTMGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN", "length": 285, "header": "tr|G5E6N7-1|G5E6N7_BOVIN Isoform 1 of Chromobox 1 OS=Bos taurus OX=9913 GN=CBX1 PE=4 SV=2 CANONICAL=G5E6N7-1" }, "locus": { "chromosome": "19", "start_pos": 38414643, "end_pos": 38395547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003835.5", "url": "https://www.ensembl.org/id/ENSBTAT00000003835.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056404.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056404.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9940465", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9940465", "resource": "Reactome", "description": "ChAHP complex assembly" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G5E6N7", "url": "https://www.uniprot.org/uniprotkb/G5E6N7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E6N7", "url": "https://www.uniprot.org/uniprotkb/G5E6N7" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "G5E6N7", "url": "https://www.uniprot.org/uniprotkb/G5E6N7" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "G5E6N7", "url": "https://www.uniprot.org/uniprotkb/G5E6N7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "G5E6N7", "url": "https://www.uniprot.org/uniprotkb/G5E6N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6N7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 285, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6N7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6N7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N7" }, { "id": "PS50013", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 179, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6N8-1", "uniprot_ac": "G5E6N8", "uniprot_id": "G5E6N8_BOVIN", "mass": { "chemical_mass": 64724.0, "monoisotopic_mass": 64724.0 }, "refseq": {}, "gene_names": [ { "name": "SYT2", "type": "recommended", "evidence": [ { "id": "G5E6N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N8" } ] } ], "protein_names": [ { "name": "Synaptotagmin", "type": "recommended", "evidence": [ { "id": "G5E6N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.", "evidence": [ { "database": "UniProtKB", "id": "G5E6N8", "url": "https://www.uniprot.org/uniprotkb/G5E6N8#function" }, { "database": "UniProtKB", "id": "RU367154", "url": "https://www.uniprot.org/uniprotkb/RU367154#function" }, { "database": "UniProtKB", "id": "A0ABI0NR64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR64#function" }, { "database": "UniProtKB", "id": "A0ABI0NTB4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB4#function" }, { "database": "UniProtKB", "id": "A0ABI0NWZ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWZ9#function" }, { "database": "UniProtKB", "id": "A0ABI0P6S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6S7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6N8", "url": "https://www.uniprot.org/uniprotkb/G5E6N8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYT2", "url": "https://www.uniprot.org/uniprotkb/G5E6N8", "locus": { "chromosome": "16", "start_pos": 80131017, "end_pos": 80126875, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047648", "url": "https://www.ensembl.org/id/ENSBTAG00000047648" } ] } } ], "crossref": [ { "id": "G5E6N8", "url": "https://alphafold.ebi.ac.uk/entry/G5E6N8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047648", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047648", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08402", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08402", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21964", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21964", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NR64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTB4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWZ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6S7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6N8", "url": "https://www.uniprot.org/uniprotkb/G5E6N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6N8-1", "url": "https://www.uniprot.org/uniprotkb/G5E6N8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLAEGVSAEDCRRAQPGGLRVCAWGPGRPQGVCVGARVRVGPVCGASSALRGLVCAAGFLTTVSSPLPVDAPGLDAWPTRLVRVVWGGVLCGEDRGGLYMGATPLLSLMHPALSAPQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQVWGQVTTSRRARPRVTRFPAAWRPCILPGPRPRGTDRCPLSSQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSGGRRAAGRRPGHPSPQAAREVGAALRKGLQGEGRALPGWRAERPPCLQLVLGVPESPWAGRFHVGVSHGPGRRMGGVGPRCSLPRTDVTRSPEPLTEPQAAAGHRGNACDHPGPGLAVRGGLRAWLLHPTDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSSATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKSK", "length": 595, "header": "tr|G5E6N8-1|G5E6N8_BOVIN Isoform 1 of Synaptotagmin OS=Bos taurus OX=9913 GN=SYT2 PE=3 SV=3 CANONICAL=G5E6N8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NR64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR64/entry", "sequence": { "sequence": "MRCPGGESGRGGSGRWASKPTGAPAGRAAQQGPASVPRLCRSSAAVLGGGWRCGAALLACQAESGSFHANPACDLGQLSDPAGPQYLHLENGGLEFMVTESLLVLLACLQLSLCHHEEHLQEEPGACGGSCHHHHARRPSGQLHRERGSGRGQGGHVCYVQGEVLQRDSQAASAPLGADRNCRGHGPSAAHLLLLHLQEVLLQEEEEQEGEGQGRQERHEHEGHAGRPAPQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSSATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKSK", "length": 535, "header": "tr|A0ABI0NR64-1|A0ABI0NR64_BOVIN Computationally mapped isoform of Synaptotagmin OS=Bos taurus OX=9913 GN=SYT2 PE=3 SV=1 CANONICAL=G5E6N8-1" }, "locus": { "chromosome": "16", "start_pos": 80130013, "end_pos": 80071784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151286.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151286.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104976.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104976.1" } ] } }, { "isoform_ac": "A0ABI0NTB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB4/entry", "sequence": { "sequence": "APSRPRAGPRARGGARTPAAPRSQSPRARGSESRWVAGRAGLSPGARGRPHPPQTSPPPRARVGRVVGWGSRWEAGSAPPADGRERPRDWREAGAEQVLLLRREGAGGAAAAGRRTRREGPALRERGVLPTALPRARAATPNRLPLSLCHHEEHLQEEPGACGGSCHHHHARRPSGQLHRERGSGRGQGGHVCYVQGEVLQRDSQAASAPLGADRNCRGHGPSAAHLLLLHLQEVLLQEEEEQEGEGQGRQERHEHEGHAGRPAPQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSSATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKSK", "length": 570, "header": "tr|A0ABI0NTB4-1|A0ABI0NTB4_BOVIN Computationally mapped isoform of Synaptotagmin OS=Bos taurus OX=9913 GN=SYT2 PE=3 SV=1 CANONICAL=G5E6N8-1" }, "locus": { "chromosome": "16", "start_pos": 80130013, "end_pos": 80070911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148250.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148250.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106628.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106628.1" } ] } }, { "isoform_ac": "A0ABI0NWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWZ9/entry", "sequence": { "sequence": "MWFSPSAPEPSRKEPTGAKRGCPSATMRSIFKRNQEPVVAPATTTMPAGPVDNSTESGGAGEGKEDMFAMFKERFFNEIVKLPLPPWALIAIAVVTGLLLLTCCFCICKKCCCKKKKNKKEKGKGAKNAMNMKDMRGGQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSSATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKSK", "length": 443, "header": "tr|A0ABI0NWZ9-1|A0ABI0NWZ9_BOVIN Computationally mapped isoform of Synaptotagmin OS=Bos taurus OX=9913 GN=SYT2 PE=3 SV=1 CANONICAL=G5E6N8-1" }, "locus": { "chromosome": "16", "start_pos": 80130013, "end_pos": 80073196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138897.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138897.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105212.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105212.1" } ] } }, { "isoform_ac": "A0ABI0P6S7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6S7/entry", "sequence": { "sequence": "MRSIFKRNQEPVVAPATTTMPAGPVDNSTESGGAGEGKEDMFAMFKERFFNEIVKLPLPPWALIAIAVVTGLLLLTCCFCICKKCCCKKKKNKKEKGKGAKNAMNMKDMRGGQMFLAEGVSAEDCRRAQPGGLRDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSSATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKSK", "length": 438, "header": "tr|A0ABI0P6S7-1|A0ABI0P6S7_BOVIN Computationally mapped isoform of Synaptotagmin OS=Bos taurus OX=9913 GN=SYT2 PE=3 SV=1 CANONICAL=G5E6N8-1" }, "locus": { "chromosome": "16", "start_pos": 80130013, "end_pos": 80125646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148644.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148644.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107551.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107551.1" } ] } }, { "isoform_ac": "G5E6N8-1", "url": "https://www.uniprot.org/uniprotkb/G5E6N8/entry", "sequence": { "sequence": "MFLAEGVSAEDCRRAQPGGLRVCAWGPGRPQGVCVGARVRVGPVCGASSALRGLVCAAGFLTTVSSPLPVDAPGLDAWPTRLVRVVWGGVLCGEDRGGLYMGATPLLSLMHPALSAPQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQVWGQVTTSRRARPRVTRFPAAWRPCILPGPRPRGTDRCPLSSQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSGGRRAAGRRPGHPSPQAAREVGAALRKGLQGEGRALPGWRAERPPCLQLVLGVPESPWAGRFHVGVSHGPGRRMGGVGPRCSLPRTDVTRSPEPLTEPQAAAGHRGNACDHPGPGLAVRGGLRAWLLHPTDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSSATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKSK", "length": 595, "header": "tr|G5E6N8-1|G5E6N8_BOVIN Isoform 1 of Synaptotagmin OS=Bos taurus OX=9913 GN=SYT2 PE=3 SV=3 CANONICAL=G5E6N8-1" }, "locus": { "chromosome": "16", "start_pos": 80130013, "end_pos": 80127074, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065643.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065643.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056405.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056405.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "G5E6N8", "url": "https://www.uniprot.org/uniprotkb/G5E6N8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "G5E6N8", "url": "https://www.uniprot.org/uniprotkb/G5E6N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6N8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 595, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6N8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6N8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N8" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 304, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002691636", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691636", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E6P4", "url": "https://www.uniprot.org/uniprotkb/G5E6P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6P4-1", "url": "https://www.uniprot.org/uniprotkb/G5E6P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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Olfactory receptor OS=Bos taurus OX=9913 GN=OR1L19 PE=3 SV=2 CANONICAL=G5E6P4-1" }, "locus": { "chromosome": "11", "start_pos": 93813438, "end_pos": 93812464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064746.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064746.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056457.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056457.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505295", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505295", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LK61-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258959", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNLTRLSEFILLGLSSHPEDQKPLFVLFLIMYLVTVMGNLLIVLAIRSDPQLQNPMYFFLSVLSFADICYTTVIVPKMLVNFLSETKTISYNECLAQMYFFLAFGNMDSYLLAAMAIDRYVAICNPFHYVTVMNHRRCVLLLAAFTAFSYLHSLLHVLLVSRLTFCASNVIHHFFCDVNPILKLACSSTSVNRVVAMTEGLASVMAPFGCIVISYLRILIAVLKIPSAAGKRKAFSTCSSHLTVVTLFYGSISYVYFQPLSSYSVKDRIATVIYTVLTSMLNPFIYSLRNKDMKRGLEKLISRIKSQMDRLSTAKAKKICGP", "length": 323 }, "evidence": [ { "id": "G5E6P4", "url": "https://omabrowser.org/oma/group/G5E6P4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8NH93-1", "protein_name": "Olfactory receptor 1L3", "gene_name": "OR1L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGMSNLTRLSEFILLGLSSRSEDQRPLFALFLIIYLVTLMGNLLIILAIHSDPRLQNPMYFFLSILSFADICYTTVIVPKMLVNFLSEKKTISYAECLAQMYFFLVFGNIDSYLLAAMAINRCVAICNPFHYVTVMNRRCCVLLLAFPITFSYFHSLLHVLLVNRLTFCTSNVIHHFFCDVNPVLKLSCSSTFVNEIVAMTEGLASVMAPFVCIIISYLRILIAVLKIPSAAGKHKAFSTCSSHLTVVILFYGSISYVYLQPLSSYTVKDRIATINYTVLTSVLNPFIYSLRNKDMKRGLQKLINKIKSQMSRFSTKTNKICGP", "length": 324 }, "evidence": [ { "id": "G5E6P4", "url": "https://omabrowser.org/oma/group/G5E6P4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G5E6P4", "url": "https://www.uniprot.org/uniprotkb/G5E6P4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G5E6P4", "url": "https://www.uniprot.org/uniprotkb/G5E6P4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E6P4", "url": "https://www.uniprot.org/uniprotkb/G5E6P4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G5E6P4", "url": "https://www.uniprot.org/uniprotkb/G5E6P4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6P4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 325, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6P4-F1.pdb", "url_external": 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"id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055141", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055141", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515581", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515581", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISPACYI", "url": "https://omabrowser.org/oma/group/ISPACYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6P9", "url": "https://www.orthodb.org/?gene=G5E6P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12374", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12374", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12374:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12374:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22941", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22941", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NKC9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6P9-1", "url": "https://www.uniprot.org/uniprotkb/G5E6P9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLRERQRRKNIARDYNLVPAFLGKDKKEKERAARRKVTKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKAAAAAAAAAGGAKRGKEDGRDGEFAAIEHLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS", "length": 427, "header": "tr|G5E6P9-1|G5E6P9_BOVIN Isoform 1 of Transcriptional adapter OS=Bos taurus OX=9913 GN=TADA2B PE=4 SV=2 CANONICAL=G5E6P9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKC9/entry", "sequence": { "sequence": "MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLRERQRRKNIARDYNLVPAFLGKDKKEKERAARRKVTKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKAAAGAKRGKEDGRDGEFAAIEHLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS", "length": 420, "header": "tr|A0ABI0NKC9-1|A0ABI0NKC9_BOVIN Computationally mapped isoform of Transcriptional adapter OS=Bos taurus OX=9913 GN=TADA2B PE=4 SV=1 CANONICAL=G5E6P9-1" }, "locus": { "chromosome": "6", "start_pos": 113524511, "end_pos": 113512036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136121.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136121.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105123.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105123.1" } ] } }, { "isoform_ac": "G5E6P9-1", "url": "https://www.uniprot.org/uniprotkb/G5E6P9/entry", "sequence": { "sequence": "MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLRERQRRKNIARDYNLVPAFLGKDKKEKERAARRKVTKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKAAAAAAAAAGGAKRGKEDGRDGEFAAIEHLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS", "length": 427, "header": "tr|G5E6P9-1|G5E6P9_BOVIN Isoform 1 of Transcriptional adapter OS=Bos taurus OX=9913 GN=TADA2B PE=4 SV=2 CANONICAL=G5E6P9-1" }, "locus": { "chromosome": "6", "start_pos": 113524511, "end_pos": 113512036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135851.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135851.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090677.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090677.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515581", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515581", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z4Z0-1", "protein_name": "Transcriptional adapter", "gene_name": "Tada2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKTLKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKRERRKENKNLASSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS", "length": 420 }, "evidence": [ { "id": "G5E6P9", "url": "https://omabrowser.org/oma/group/G5E6P9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7EYV9-1", "protein_name": "Transcriptional adapter 2-beta", "gene_name": "Tada2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQREAPARRRRAKALLSARGRARGACAMRRGDGGGGGGGRAGPEGACVLRRDAARLAGSGGAWAGAAVAAAGSGAGAAGAASPAGGGALTAGGAAAAGRAAGERGKMAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKTLKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKRERRKENKNLASSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS", "length": 527 }, "evidence": [ { "id": "G5E6P9", "url": "https://omabrowser.org/oma/group/G5E6P9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LTB2-1", "protein_name": "Transcriptional adapter", "gene_name": "TADA2B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKAAKRKVTKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENRNTGGSKRGKEDGKDGEFAAIEHLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGVPAKSRLPGYLDKVLKKRILNFLTESGWISRDAS", "length": 420 }, "evidence": [ { "id": "G5E6P9", "url": "https://omabrowser.org/oma/group/G5E6P9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86TJ2-1", "protein_name": "Transcriptional adapter 2-beta", "gene_name": "TADA2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELGKKYCVYCLAEVSPLRFRCTECQDIELCPECFSAGAEIGHHRRYHGYQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHYVSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLRDDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVPAFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRELQRYRRNGITKMEESAEYEAARHKREKRKENKNLAGSKRGKEDGKDSEFAAIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDHLQKRQGIPSKSRLPSYLDKVLKKRILNFLTESGWISRDAS", "length": 420 }, "evidence": [ { "id": "G5E6P9", "url": "https://omabrowser.org/oma/group/G5E6P9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "SAGA-type complex", "id": "GO:0070461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070461", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G5E6P9", "url": "https://www.uniprot.org/uniprotkb/G5E6P9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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OX=9913 GN=EPOP PE=4 SV=1 CANONICAL=G5E6S7-1" }, "isoforms": [ { "isoform_ac": "G5E6S7-1", "url": "https://www.uniprot.org/uniprotkb/G5E6S7/entry", "sequence": { "sequence": "METLCPAPRLAVPGSPRGSPCSPTPRKPRRGTQEFSPLCLRALAFCALAKPRASSLGLGPGELAPRAPVLLGPCAPLCTGGRAPDGLKHLAGQAGRSSDPNAPARQDADAAVCRGRGEEEEGGGSFPHFSARSGVPPGHCPAPRRPRESPTSSVSAPPRPALALDSQPGPAASPHQEPGSRPPPPPAGLSSEPMGPGAAPEPPPPNQTAAVDGNPPKVAPEAPASSPSTASEAPAAPGDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRRPAPPQRSAQPRRPTPTLPTTSTFNLLDCFPCPPALVLGEDGDLGPASSLRLQGDAKPPPAHPLWRWQIGGPAVPEPPGLKFWGINLEQP", "length": 379, "header": "tr|G5E6S7-1|G5E6S7_BOVIN Isoform 1 of Elongin BC and polycomb repressive complex 2 associated protein OS=Bos taurus OX=9913 GN=EPOP PE=4 SV=1 CANONICAL=G5E6S7-1" }, "locus": { "chromosome": "19", "start_pos": 39275354, "end_pos": 39274218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064066.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064066.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056490.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056490.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100296460", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100296460", "resource": "KEGG Pathway" }, { "id": "R-BTA-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BRN1-1", "protein_name": "Elongin BC and polycomb repressive complex 2 associated protein", "gene_name": "EPOP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METLCPAPRLAVPASPRGSPCSPTPRKPRRGTQEFSPLCLRALAFCALAKPRASSLGLGPGELAPRAPVLLGPRAPLCTGGWAPDGLKHLAGQAGRSSDPNSPARQDADAAVCRGRSEEEEGGGSFPHFGARSGLPPGRCPAPRRPRESPTSSASAPPRPAPGLDSQPGFAASPHQDPGSRPPPPPAGLSSEPAGPRAAPEPPLPGQTAAVDGNPPKAAPEAPAASPSTASGAAAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRRPAPPQRSAQPRRPAPTLPTTSTFSLLDCFPCPPALVVGEDGDLGPASSLRLQGDSKPPPAHPLWRWQIGGPAVPEPPGLKFWGINLEQL", "length": 379 }, "evidence": [ { "id": "G5E6S7", "url": "https://omabrowser.org/oma/group/G5E6S7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6NHQ4-1", "protein_name": "Elongin BC and Polycomb repressive complex 2-associated protein", "gene_name": "EPOP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPGLKFWGINMDES", "length": 379 }, "evidence": [ { "id": "G5E6S7", "url": "https://omabrowser.org/oma/group/G5E6S7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "M0RD31-1", "protein_name": "Elongin BC and polycomb repressive complex 2 associated protein", "gene_name": "Epop", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METLCPPPRLAVPASPRGSPCSPTPRKPRRGTPEFSPLCLRALAFCALAKPRPSSLGLGPGELAPRTPVLLGSRASPCTGGWAADGLKHLGAQAGRPSDVSSATREDADVAVCPDRGEEEEGGGGFPHFGSGSCTPPGRCPAGPRESPTSPARSPPRPARGLESQLDAASSPPLGSSSRPPSPPAGLSPEPAPTEQPMRDSEAPEGGDPARVAPEAPALSPSTADATPDAPGDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPAAKARGAAKKRRRPAPPPRSVQPRRPAPTLPTSSTFHLLDCFPCPPALVVEENGDLGPASSLRLQGDAKPPPAHPLWKWQMGGPAVPEPPGLKSWWVNLEEL", "length": 371 }, "evidence": [ { "id": "G5E6S7", "url": "https://omabrowser.org/oma/group/G5E6S7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TNS8-1", "protein_name": "Elongin BC and Polycomb repressive complex 2-associated protein", "gene_name": "Epop", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METLCPPPRLAVPASPRGSPCSPTPLKPRRGTPEFSPLCLRALAFCALAKPRPSSLGLGPGELAPRTPVLLGPPASPCTGGWAADGLKHLGGQAGRPSDVSSPAREDADVAVCPGGGEEEEGGGGFPHFGAGSCAPPGRCPAPLRPQDSPTNPAWSPPRPARGLDAASSPPLEPGSPPPSPPAGLSPEPAPSEQPVPASEAPGGGDPAPTAPEAPALSPSTADAAPDPPRDLRQEHFNRLIRRSKLWCYAKGFALDTPSLRRGPERPAAKARGAAKKRRRPAPPPPSVQPRRPVPTLPTSSTFSLLDCFPCPPALVVEENGDLGPASSLRLQGDAKPPPAHPLWKWQMGGPAVPEPPGLKSWWVNLEEL", "length": 369 }, "evidence": [ { "id": "G5E6S7", "url": "https://omabrowser.org/oma/group/G5E6S7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" }, { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" }, { "name": "neuron fate commitment", "id": "GO:0048663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048663", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" }, { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" }, { "name": "elongin complex", "id": "GO:0070449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070449", "evidence": [ { "database": "UniProtKB", "id": "G5E6S7", "url": "https://www.uniprot.org/uniprotkb/G5E6S7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6S7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 379, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6S7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6S7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6T3-1", "uniprot_ac": "G5E6T3", "uniprot_id": "G5E6T3_BOVIN", "mass": { "chemical_mass": 87709.0, "monoisotopic_mass": 87709.0 }, "refseq": { "ac": "NP_001193478", "name": "protein ELFN1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193478" }, "gene_names": [ { "name": "ELFN1", "type": "recommended", "evidence": [ { "id": "G5E6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ] }, { "name": "ELFN1", "type": "synonym", "evidence": [ { "id": "NP_001193478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193478" } ] } ], "protein_names": [ { "name": "Extracellular leucine rich repeat and fibronectin type III domain containing 1", "type": "synonym", "evidence": [ { "id": "G5E6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6T3/entry#names_and_taxonomy" } ] }, { "name": "protein ELFN1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001193478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193478" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ELFN1", "url": "https://www.uniprot.org/uniprotkb/G5E6T3", "locus": { "chromosome": "25", "start_pos": 41261748, "end_pos": 41326142, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030757", "url": "https://www.ensembl.org/id/ENSBTAG00000030757" } ] } } ], "crossref": [ { "id": "ENSBTAG00000030757", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618774", "url": "https://www.ncbi.nlm.nih.gov/gene/618774", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618774", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618774", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCELYSN", "url": "https://omabrowser.org/oma/group/TCELYSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6T3", "url": "https://www.orthodb.org/?gene=G5E6T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193478", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193478", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6T3-1", "url": "https://www.uniprot.org/uniprotkb/G5E6T3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGCGWEAPWVWVCVAAALLHAGGLVRGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYAALSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGVLRGLGKLEYLYLQANLIEAVAPGAFWECPNIVNVDLSMNRIQRLHSATFAGLARLSVCELYSNPFYCSCELLGFLRWLAAFANATQAHDRVQCESPPLYSGYFLLGQGRHGQRSILGKLQSVCTDGPYAAETRPAPGRPPPGRSPPPPPVPPAEPSEAPCAEDECFSGDGTTPLVALPTLAPQAEARPLIKVKQLTQNSATITVQLPSPFTRMYTLEHFNNSKSSTVSRLTRAQEEIRLTNLYALTNYTYCVVSSSSGLHHNHTCLTICLPQPPSPPGPVPSPSTATHYIMTVLGCLFGMVVVLGAVYYCLRRRRRREGKQKQAAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAPGEVEQYQLAEGSGTPKGSKGGYMEVRAAEQAERREGEQGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKAEATSFQGGKPGAVSTAEPLAGKRGFLAPAYQDACGLQRHHSLEAAPGAPRASSSSSGSARSPRPYRAEPPALHEAKYIEKGSPAAEAILTVTPAAAVLRPEPEKGRQYGEHRHSYPGPHPVEPPAPPAPPESLGGRKASILEPLTRPRPRDLAYAPLSPQYRHLSYASSPEYACRASRSLWARFRLSRPRHRDAGECVAAGHALRRKVQFAKDEDLHDILDYWKGVSAQHKS", "length": 808, "header": "tr|G5E6T3-1|G5E6T3_BOVIN Isoform 1 of Extracellular leucine rich repeat and fibronectin type III domain containing 1 OS=Bos taurus OX=9913 GN=ELFN1 PE=4 SV=2 CANONICAL=G5E6T3-1" }, "isoforms": [ { "isoform_ac": "G5E6T3-1", "url": "https://www.uniprot.org/uniprotkb/G5E6T3/entry", "sequence": { "sequence": "MAGCGWEAPWVWVCVAAALLHAGGLVRGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYAALSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGVLRGLGKLEYLYLQANLIEAVAPGAFWECPNIVNVDLSMNRIQRLHSATFAGLARLSVCELYSNPFYCSCELLGFLRWLAAFANATQAHDRVQCESPPLYSGYFLLGQGRHGQRSILGKLQSVCTDGPYAAETRPAPGRPPPGRSPPPPPVPPAEPSEAPCAEDECFSGDGTTPLVALPTLAPQAEARPLIKVKQLTQNSATITVQLPSPFTRMYTLEHFNNSKSSTVSRLTRAQEEIRLTNLYALTNYTYCVVSSSSGLHHNHTCLTICLPQPPSPPGPVPSPSTATHYIMTVLGCLFGMVVVLGAVYYCLRRRRRREGKQKQAAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAPGEVEQYQLAEGSGTPKGSKGGYMEVRAAEQAERREGEQGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKAEATSFQGGKPGAVSTAEPLAGKRGFLAPAYQDACGLQRHHSLEAAPGAPRASSSSSGSARSPRPYRAEPPALHEAKYIEKGSPAAEAILTVTPAAAVLRPEPEKGRQYGEHRHSYPGPHPVEPPAPPAPPESLGGRKASILEPLTRPRPRDLAYAPLSPQYRHLSYASSPEYACRASRSLWARFRLSRPRHRDAGECVAAGHALRRKVQFAKDEDLHDILDYWKGVSAQHKS", "length": 808, "header": "tr|G5E6T3-1|G5E6T3_BOVIN Isoform 1 of Extracellular leucine rich repeat and fibronectin type III domain containing 1 OS=Bos taurus OX=9913 GN=ELFN1 PE=4 SV=2 CANONICAL=G5E6T3-1" }, "locus": { "chromosome": "25", "start_pos": 41264963, "end_pos": 41262540, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133594.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133594.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103439.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618774", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618774", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZ44-1", "protein_name": "Extracellular leucine-rich repeat and fibronectin type III domain containing 1", "gene_name": "Elfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGHGWGAPWVLVAAATLLHACGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQGRHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPPEPSDMPCADDECFSGDGTTPLVVLTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAVAAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESGETPKATKGNYIEVRTGEPPERRGCELSRPAPETQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAATGPPRASTSSSGSARSPRTFRAETAGAHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPPPPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "length": 829 }, "evidence": [ { "id": "G5E6T3", "url": "https://omabrowser.org/oma/group/G5E6T3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LFQ3-1", "protein_name": "Extracellular leucine rich repeat and fibronectin type III domain containing 1", "gene_name": "ELFN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGRRWGALWVCVAAAALLHAGGLARGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYAALSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGVLRGLSKLEYLYLQANLIEVVTPSAFWECPNIVNVDLSMNRIQRLHSATFAGLARLSVCELYSNPFYCSCELLGFLRWLAAFTNATHAYDRMQCESPPLYAGYFLLGQGRHGQRSILSKLQSVCTDGSYAAETRPAPPGRAPPPPPPPPPPSEPSEAPCADDECFSGDGTTPLVALPTLATQAEARPLIKVKQLTQDSATLTVQLPSPFNRMYTLEHFNNSKSSTVSRLTRAQEEIRLTNLYALTNYTYCVVSTSSGLHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEQHKKAAAAAAAGGLQKTLLELKYGPGVEAPGLAPLSQGPLLGPEAVTRVPYLPAAAGEVEQYTLVESGETPKAGKGHYMEVRTGEPAERRDCERGRPGPGSQSSVAEISTIAREVDKVNQIINSCIDALKSEATSFQGGKSGAVAAAEPPLVVLSEPLAGKHGFLSPVYKDSFGHGLQRHHSVEAAPGAPRASTSSSGSARSPRPYRAETAAAAAVHKAAAAEAKYIEKTSPATDAILTVTPAAAVLRAEAEKSRQYGEHRHSYPGSHPAEPPTSPARPPPEGLGGRKASILEPLTRPRPRDLAYSQLSPQYHNLSYSSSPEHPCRPSQSIWERLRLSRRRHRDDDGEFVAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "length": 828 }, "evidence": [ { "id": "G5E6T3", "url": "https://omabrowser.org/oma/group/G5E6T3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C7U0-1", "protein_name": "Protein ELFN1", "gene_name": "ELFN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGRGWGALWVCVAAATLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGQGRRGHRSILSKLQSVCTEDSYAAEVVGPPRPASGRSQPGRSPPPPPPPEPSDMPCADDECFSGDGTTPLVALPTLATQAEARPLIKVKQLTQNSATITVQLPSPFHRMYTLEHFNNSKASTVSRLTKAQEEIRLTNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEKHKKAASAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAGEVEQYKLVESADTPKASKGSYMEVRTGDPPERRDCELGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGPVSVAEPPLVLLSEPLAAKHGFLAPGYKDAFGHSLQRHHSVEAAGPPRASTSSSGSVRSPRAFRAEAVGVHKAAAAEAKYIEKGSPAADAILTVTPAAAVLRAEAEKGRQYGEHRHSYPGSHPAEPPAPPGPPPPPPHEGLGRKASILEPLTRPRPRDLAYSQLSPQYHSLSYSSSPEYTCRASQSIWERFRLSRRRHKEEEEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "length": 828 }, "evidence": [ { "id": "G5E6T3", "url": "https://omabrowser.org/oma/group/G5E6T3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C8T7-1", "protein_name": "Protein ELFN1", "gene_name": "Elfn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGHGWGTAWVLVAAATLLHAGGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQGRHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPPEPSDMPCADDECFSGDGTTPLVILTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAVAAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESSETPKATKGNYIEVRTGEPQERRGCELSRPGEPQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAAPGPPRASTSSSGSARSPRTFRAEATGTHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPPPPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "length": 828 }, "evidence": [ { "id": "G5E6T3", "url": "https://omabrowser.org/oma/group/G5E6T3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "G5E6T3", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6T3" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 240, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 60, "end_pos": 62 }, { "start_pos": 86, "end_pos": 88 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G7H7V7-1", "uniprot_ac": "G7H7V7", "uniprot_id": "TOPZ1_BOVIN", "mass": { "chemical_mass": 185726.0, "monoisotopic_mass": 185726.0 }, "refseq": { "ac": "NP_001239370", "name": "protein TOPAZ1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" }, "gene_names": [ { "name": "TOPAZ1", "type": "recommended", "evidence": [ { "id": "G7H7V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G7H7V7" } ] }, { "name": "C22H3orf77", "type": "synonym", "evidence": [ { "id": "NP_001239370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" } ] }, { "name": "TOPAZ1", "type": "synonym", "evidence": [ { "id": "NP_001239370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" } ] } ], "protein_names": [ { "name": "Protein TOPAZ1", "type": "recommended", "evidence": [ { "id": "G7H7V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G7H7V7/entry#names_and_taxonomy" } ] }, { "name": "Testis- and ovary-specific PAZ domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001239370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" }, { "id": "G7H7V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G7H7V7/entry#names_and_taxonomy" } ] }, { "name": "protein TOPAZ1", "type": "synonym", "evidence": [ { "id": "NP_001239370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" } ] }, { "name": "testis and ovary specific PAZ domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001239370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" } ] }, { "name": "testis and ovary-specific PAZ domain gene 1", "type": "synonym", "evidence": [ { "id": "NP_001239370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" } ] }, { "name": "topaz 1", "type": "synonym", "evidence": [ { "id": "NP_001239370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370" } ] } ], "function": [ { "annotation": "Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.", "evidence": [ { "database": "UniProtKB", "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7#function" }, { "database": "UniProtKB", "id": "E5FYH1", "url": "https://www.uniprot.org/uniprotkb/E5FYH1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TOPAZ1", "url": "https://www.uniprot.org/uniprotkb/G7H7V7", "locus": { "chromosome": "22", "start_pos": 16269861, "end_pos": 16209094, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044167", "url": "https://www.ensembl.org/id/ENSBTAG00000044167" } ] } } ], "crossref": [ { "id": "G7H7V7", "url": "https://alphafold.ebi.ac.uk/entry/G7H7V7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044167", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100296400", "url": "https://www.ncbi.nlm.nih.gov/gene/100296400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100296400", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100296400", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPNEYHI", "url": "https://omabrowser.org/oma/group/SPNEYHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G7H7V7", "url": "https://www.orthodb.org/?gene=G7H7V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35671:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35671:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001239370", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239370", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G7H7V7-1", "url": "https://www.uniprot.org/uniprotkb/G7H7V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAPPSGPTTAPGREDDARGLRKRSRRPGLGEAGGCGPEAEGLEESRQKRRMVARASGREEVESDKSAKEKRKVTEASSDDPQPGIDLVRKESLTSSESFPTVECSEFQSMAFLQSLGKERLVEGIKRRIRIKKCKSLESPALKMTENKATQNSKVEFQDELYKNTLKYSCNSLSPGVENNSVLKLHDCSCLSHSKDCNDENNLAYKPDGGCMHVPENSSKSKKENPRSLIDKTDPSNIPQLLQTEENVMRVSQLLLEENDSYLSKNNGLFSCLQSEKTKHSIEESSIGRKSRKRMKVSEKGNGMVIEMKFSNMCNKSELMLQGNQTGADGKETEILEAKKSSLKVLRKVNNNTLSPMDPLLSLPETGKKTSPEHCANAVFQKALEQLSKEETKNVSQPLGCTSMDPPEDYFKSMKNSLVKSLSDCFPIEKRSSRESLKNEAEESKYSCQRTIPMTGKRTWPCYSCARISAQCWKKASLPQSSRQDDFLKHQMNQTHLTDSKLMLQSSVTETNSASSSIEKLDSNLNCLPSVSTVEPTSVVIKEPIVNDDEKMKSEELSRSASEVVSNTTEDTSLTNMTHNLTGSKKKDRGNLTKLNLTVASQDGQEANNSTSKTVHRKACITKQALVVPDLVKILNTGRLTNFKIPLLKNKTEKRKEINAKSSEREVYSPLELLDSVSGAEVRQSRTKENAVTVTSGPQSLSIQRSVIPVQASSDSFCSKNSCIIAPSFLKQGNNKQPSNHISASGRIISNNAAGSLTVENNTFSCDPGCIEKNPTFYSNEQEPFKAVSSEVSGRKMTENFSEIKVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFPSEVPMISQEPNVAEEHQSTDSKHMELPDKKEPSNALRELPVPDPGSMKSEICASLSAASEIKHDSKDANISLGEVTHETSSNEKPRGLSEQTKSSDLDEKCRFSDKVAIREEKETISEVCRRDSKNTEIMVGECHLAALVSKPLCLPVPLPPLNLNAHQEDTLLNPQMNDFRLPGKHSVLKLQNPEICEIFKREKNVGVFQKPLGLMIPHRYCKFHFNTLRGCERSQCKFGHVPEQGDEKVCMDVFKKYISINELCLLQRAANMFMEYYRKFLPGIHFDLQVLNDLLSSLLKHCLLKEVFQVMNLCIMIKMLPALKILLKIFEYVATMKLRNAVPALINIFCKLLEAGMVLDPEHFNYIVKLLYQVQASKQEITAVLEMKSRLHMRQFKKNWKCDLEAALNEIEHCKEKGDWTKLGNVYLNIKMSCEKFADFQRFCACIAETLTKDCKEERPGVPFCEFAETVSKDLQNSEVDKTLLGRIGISAMYFYHKLLQWSKGRKVLDKLYELKIHFTSLKGLIGPEKLAPRCQIVNIAAEIFLKSGSLDGAIWVLRESEWIINTPVWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSLLFNKLLDACIESNSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFLVSNASSIQSPGTSTQMLQIVLKRSEENKSRSKDDYQAAVERLITAARISDPKLFIKHMTVNVNKEQVYSLEQCSALKWLKENMKWAGKVWLFNNH", "length": 1653, "header": "sp|G7H7V7-1|TOPZ1_BOVIN Isoform 1 of Protein TOPAZ1 OS=Bos taurus OX=9913 GN=TOPAZ1 PE=2 SV=1 CANONICAL=G7H7V7-1" }, "isoforms": [ { "isoform_ac": "G7H7V7-1", "url": "https://www.uniprot.org/uniprotkb/G7H7V7/entry#G7H7V7-1", "sequence": { "sequence": "MPRAPPSGPTTAPGREDDARGLRKRSRRPGLGEAGGCGPEAEGLEESRQKRRMVARASGREEVESDKSAKEKRKVTEASSDDPQPGIDLVRKESLTSSESFPTVECSEFQSMAFLQSLGKERLVEGIKRRIRIKKCKSLESPALKMTENKATQNSKVEFQDELYKNTLKYSCNSLSPGVENNSVLKLHDCSCLSHSKDCNDENNLAYKPDGGCMHVPENSSKSKKENPRSLIDKTDPSNIPQLLQTEENVMRVSQLLLEENDSYLSKNNGLFSCLQSEKTKHSIEESSIGRKSRKRMKVSEKGNGMVIEMKFSNMCNKSELMLQGNQTGADGKETEILEAKKSSLKVLRKVNNNTLSPMDPLLSLPETGKKTSPEHCANAVFQKALEQLSKEETKNVSQPLGCTSMDPPEDYFKSMKNSLVKSLSDCFPIEKRSSRESLKNEAEESKYSCQRTIPMTGKRTWPCYSCARISAQCWKKASLPQSSRQDDFLKHQMNQTHLTDSKLMLQSSVTETNSASSSIEKLDSNLNCLPSVSTVEPTSVVIKEPIVNDDEKMKSEELSRSASEVVSNTTEDTSLTNMTHNLTGSKKKDRGNLTKLNLTVASQDGQEANNSTSKTVHRKACITKQALVVPDLVKILNTGRLTNFKIPLLKNKTEKRKEINAKSSEREVYSPLELLDSVSGAEVRQSRTKENAVTVTSGPQSLSIQRSVIPVQASSDSFCSKNSCIIAPSFLKQGNNKQPSNHISASGRIISNNAAGSLTVENNTFSCDPGCIEKNPTFYSNEQEPFKAVSSEVSGRKMTENFSEIKVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFPSEVPMISQEPNVAEEHQSTDSKHMELPDKKEPSNALRELPVPDPGSMKSEICASLSAASEIKHDSKDANISLGEVTHETSSNEKPRGLSEQTKSSDLDEKCRFSDKVAIREEKETISEVCRRDSKNTEIMVGECHLAALVSKPLCLPVPLPPLNLNAHQEDTLLNPQMNDFRLPGKHSVLKLQNPEICEIFKREKNVGVFQKPLGLMIPHRYCKFHFNTLRGCERSQCKFGHVPEQGDEKVCMDVFKKYISINELCLLQRAANMFMEYYRKFLPGIHFDLQVLNDLLSSLLKHCLLKEVFQVMNLCIMIKMLPALKILLKIFEYVATMKLRNAVPALINIFCKLLEAGMVLDPEHFNYIVKLLYQVQASKQEITAVLEMKSRLHMRQFKKNWKCDLEAALNEIEHCKEKGDWTKLGNVYLNIKMSCEKFADFQRFCACIAETLTKDCKEERPGVPFCEFAETVSKDLQNSEVDKTLLGRIGISAMYFYHKLLQWSKGRKVLDKLYELKIHFTSLKGLIGPEKLAPRCQIVNIAAEIFLKSGSLDGAIWVLRESEWIINTPVWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSLLFNKLLDACIESNSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFLVSNASSIQSPGTSTQMLQIVLKRSEENKSRSKDDYQAAVERLITAARISDPKLFIKHMTVNVNKEQVYSLEQCSALKWLKENMKWAGKVWLFNNH", "length": 1653, "header": "sp|G7H7V7-1|TOPZ1_BOVIN Isoform 1 of Protein TOPAZ1 OS=Bos taurus OX=9913 GN=TOPAZ1 PE=2 SV=1 CANONICAL=G7H7V7-1" }, "locus": { "chromosome": "22", "start_pos": 16269701, "end_pos": 16209293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061088.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061088.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053356.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053356.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 10, "start_aa": "Thr", "end_pos": 10, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr10", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] }, { "title": "TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates.", "journal": "PLoS ONE", "date": "2011", "authors": "Baillet A, Le Bouffant R, Volff JN, Luangpraseuth A, Poumerol E, Thepot D, Pailhoux E, Livera G, Cotinot C, Mandon-Pepin B", "evidence": [ { "database": "UniProtKB", "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7" } ], "reference": [ { "type": "PubMed", "id": "22069478", "url": "https://glygen.org/publication/PubMed/22069478" } ] } ], "pathway": [ { "id": "bta:100296400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100296400", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUC6-1", "protein_name": "Protein TOPAZ1", "gene_name": "Topaz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPPTTPPVPTTAPGRQGATGGLRKRGLRLTPEPGEGGGCSLEARGREEESRQKRRMVAQASGREETEAKENGKVTEAPSDEPQPGTDLVRKTSITNSESLQTVECSEFQSMAFLQSLAKEELVEGIKRRIQIKKCKSSENPPLKITKNEATQNIMVESQDELFKNTPKYSCNSLSPGVEKNCSFESHDFSFLHSEGCNNKNGFEDEPHGVCLHAEENSLKSKKENLRNLAEKDDTKTTKFLKTEKNVIASKLLLEESHLYQNKNNGLTSCLQSEKNKYSVEENNTGRKHRKKMKLSEKEEKGIDLTLSNVCNNSELVLQEHQIGMEGKETETLEHKKSFLKALRKMNHNTLPPVDHLCLPETVGKTSCRHSTNVVLQKTLESSLKEDTKNASETLGCRRLQPEEYFKSMTSSTVKSPSDSHPMGKRSPRGDLKTDTEESKVSCRRIIPMTGKRVWPLYSCARITAECWKKTSLSDLNDSLPGSLGNVRQHDFLMHQTNQTHLPDSKRLQPSLIERTIESSSKEVYDSELSSLSSVSSVEPTLLDIKETIPHDKKTKLEEPSRNGTEVVSSATEDIQLSNITQILTGNKKKKGNLSKLNLTVAPQESQEANNCANKTVHRKACITKQTLVAPDLVKILNTGRLTNFKIPLLKNKTGKRGEVSARSSEREAYSPLELLDSLSGVEAKQNRNKENICTTSGPQSLNIHSVTPGQTSSHTFYNKNSCTSPSFTKKGYDNKTCNHISETGNTISNKESLSIKIENNTFSCDLGYMEQSSFCSKKQEAFVPISSEISGRKMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQEPRVSEEHPSADFKHRHLPGKKEPGDLSKEVALLDPGLLKLEICPSLSAAKEPQHDPKGAAISLEATEETVISENLEDLSEQARASDSDTKCVSSDKATVVEEQENTHEVCKSKDSRSVEAVSTECHLALGPNTLCSSAPPLTLSSHQDVAPAPWTNDFRFPGRYSVLQLQNPETCEIFKREKNFGVFQKPLGLMIPHRYCKLHFNTLRGCERAQCKFVHVPEQGDEKICMDVFKKYIRVNEQRLLHRAAYIFLEYYRKFPPGIHFSLQVLNDLLISLLKHCLLKEVFQVVQLSIMAKMLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMIPDPEHLNYIVKLLHQAQASQQEISAVLEAKSRLQVRQLRKNWTCDLDSALSEVENCKEKGDWTKLGNLYISIKMGCEEFADFQRFCACVAETLTEDYKEERPGVPFCEFAETVSKDPQYSEVDKTLLGRIGISAVYFYHRLLLWSKGRKVLDILYELKIHFTSLKGLTGPEKIAPRCQIVNVAAEIFIKSGSLDGAIWVLRESEWITSTPLWPCDRADVLHRHNLLCAIAHEILGKNLYKQTFEVLRNLPGFQNSQEAMGVSQSSLLFNELLDACIESNSLGISSSVADFMVAKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNVYRKLLLVPSYLSEIEMLLAIEIFLVSNASSIQSPGAPTQVLQIVLKRCEESKPRSKDDYQAAVERLIMAARISDPKLFIKHMTVNINKEQVYSLEHCSAVKWLKENMKWAGKVWLFTNH", "length": 1646 }, "evidence": [ { "id": "G7H7V7", "url": "https://omabrowser.org/oma/group/G7H7V7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E5FYH1-1", "protein_name": "Protein TOPAZ1", "gene_name": "Topaz1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPPATPPDPTKEPGCKGTTRGLRKRGLPLTPEPGEGGGCSLEARGCEEESRQKQRMVTQASGREETEGDKLAKENGKITEAPSDDPQPGTDLVRKTSITSSESLQTVECSEFQNMAFLQSLDKEELGEGIKRRMRIKKCKSLENPPLEITKNEATQNIKVEFQDELFKNTPKHSCNSLSPGVEKNCSFELHDYSFLHSEGCNNENNFEDKPHDVCLHTEENSLKLKKENLRNLAEKDDTRTTTKLLKTEKSVIASKLLLEESHLYQNKNNGLTSCLQSEKNKYSVEENNTGRKHRKKMKSGKEEKNINLTLSNVCNNSVLVLQENQMGMEGKEAETLEPKKSFLKALRKINHNTLPPVDHLCLPKTVGKTSSRHHINAMLQKTLESSLKEDIKNTSESLGCKRIEPEKYNKSMISSTVKSPSDGHHMEKRSPRGDLRSETEESKVSCCRTIPMTGKRVWPFYSCARISAQCWKKTSLSDLNYSLLGPLENVRQHDSIIHQMNQTHLPDSKLLQPSLTERTTESSRKEMYDSDLSCLSSVSSVESTVMDIKEAMSHDKKTKLEEPSRNGAEVVSNATEDTQLSNITQSLTGNKKRKGNLSKLNLTVASQESQETNNCANKTVHRKVCITKQTLVAPDLVKILNTGRLTNFKIPLLKNKTGKRGAVSARSSEREAYSPLELLDSLSGVEAKQNRNKENICTTSGPQSLNLHSCIAPGQASSHSFYNKNSCTSSSFTKKGYDNKACNHISEPGNIISNKESISMKIENNTFSCDLGYIDQSSFCSKKQEAFVPISSEISGRKMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQEPRVSEDQPTADFKHMHLPGKKEPGDLSKEVALLDPGLLKLESCPSLSAAKEPQHDPEGAAISLEATEETVVSGSLEGLSEQARASDSDAKCISSDKATVMEEQESTHEIFKSKDSRNVESATECQLATLGPNPLCSSALPVNLSSHQDVVSTPWINDVRFPGRHSVLQLQNPETCEIFKREKNMGVFQKPLGLLIPHRYCKLHFNTLRGCERAQCKFVHVPEQGDEKICMDVFRKYISVNEQRLLHRAAYIFLEYYRKFPPGIHFSLQVLNDLLISLLKHCLLKEVFQVVQLSIMAKMLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMVPDPEHLNYIVKLLHQAQASQQEISAVLQAKSRLRVRQLKKNWKCDLDSALSEVETCKEKSDWTKLGNLYISIKMSCEEFADLQRFCACVAETLTEDYKEERPGVPFCEFAETVSKDPQYSEVDKTLLGRIGISAVYFYHRLLLWAKGRKVLDILYELKIHFTSLKGLTGPEKEAPRCQIVNVAAEIFIKSGSLDGAIWVLRESEWIINTPLWPCDRMDVLNRHNLLCTIAHEILGKNLYKQTFEVLRNLPSFQNSQEMMGVSQSSLLFNELLDACIESNSLGISSSVAEFMVAKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLHRKLLLVPSYLSEIEMLLAMEIFLVSNASGIQSAGMGAPTQVLQIVLKRCEESKSRSKDEYQAAVERLVMAARISDPKLFIKHMTVNINKEQVYSLEHCSALKWLKENMKWAGKVWLFTNH", "length": 1653 }, "evidence": [ { "id": "G7H7V7", "url": "https://omabrowser.org/oma/group/G7H7V7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N9V7-1", "protein_name": "Protein TOPAZ1", "gene_name": "TOPAZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGCRENKQKRRMVARATPGRGEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRRGSEVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDNLSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNSKPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRKITKNFSEVGFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEVANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGECQFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKNVGVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELCLLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLKILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAVLEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFCACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSKGRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWIINTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSLLFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSALSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKRCEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENMKWAGKVWLFSNH", "length": 1692 }, "evidence": [ { "id": "G7H7V7", "url": "https://omabrowser.org/oma/group/G7H7V7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7" } ], "pmid": "" }, { "name": "spermatocyte division", "id": "GO:0048137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048137", "evidence": [ { "database": "UniProtKB", "id": "G7H7V7", "url": "https://www.uniprot.org/uniprotkb/G7H7V7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1561, "end_pos": 1563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1585, "end_pos": 1587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376779" }, "gene_names": [ { "name": "OR13C11", "type": "recommended", "evidence": [ { "id": "M0QW35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0QW35" } ] }, { "name": "OR13C11", "type": "synonym", "evidence": [ { "id": "NP_001376779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376779" } ] }, { "name": "OR2S2", "type": "synonym", "evidence": [ { "id": "NP_001376779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376779" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "M0QW35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0QW35/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 13 subfamily C member 11", "type": "synonym", "evidence": [ { "id": "NP_001376779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376779" } ] }, { "name": "olfactory receptor, family 2, subfamily S, member 2", "type": "synonym", "evidence": [ { "id": "NP_001376779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376779" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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[provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376779", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376779" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR13C11", "url": "https://www.uniprot.org/uniprotkb/M0QW35", "locus": { "chromosome": "8", "start_pos": 60258993, "end_pos": 60259952, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000057004", "url": "https://www.ensembl.org/id/ENSBTAG00000057004" } ] } } ], "crossref": [ { "id": "M0QW35", "url": "https://alphafold.ebi.ac.uk/entry/M0QW35", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049084", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049084", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509916", "url": "https://www.ncbi.nlm.nih.gov/gene/509916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509916", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509916", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SQKCFRR", "url": "https://omabrowser.org/oma/group/SQKCFRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "M0QW35", "url": "https://www.orthodb.org/?gene=M0QW35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381753", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376779", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376779", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M0QW35-1", "url": "https://www.uniprot.org/uniprotkb/M0QW35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKPNQTSPLVGFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILVTILDSRLHMPMYFFLENLSFLDICYTTSSVPLVLDSFLTPQKTISFSACAMQMFLSFSMAGTECVLLSMMAFDRYVAICNPLRYSVVMSKAVYVPMAAGSWAIGGVASLVHTSLVIQLPFCGANIINHFTCEILAVLKLACADISISVISMEVTNVIFLGVPVLFISVSYVFIIATILRIPSAEGKKKAFSTCSAHLTVVIIFYGTLFFMYGKPKSKDSQGADKEDLADKLIPLFYGVVIPMLNPIIYSLRNNDVKAAVRNLVSQKCFRR", "length": 319, "header": "tr|M0QW35-1|M0QW35_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR13C11 PE=3 SV=1 CANONICAL=M0QW35-1" }, "isoforms": [ { "isoform_ac": "M0QW35-1", "url": "https://www.uniprot.org/uniprotkb/M0QW35/entry", "sequence": { "sequence": "MEKPNQTSPLVGFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILVTILDSRLHMPMYFFLENLSFLDICYTTSSVPLVLDSFLTPQKTISFSACAMQMFLSFSMAGTECVLLSMMAFDRYVAICNPLRYSVVMSKAVYVPMAAGSWAIGGVASLVHTSLVIQLPFCGANIINHFTCEILAVLKLACADISISVISMEVTNVIFLGVPVLFISVSYVFIIATILRIPSAEGKKKAFSTCSAHLTVVIIFYGTLFFMYGKPKSKDSQGADKEDLADKLIPLFYGVVIPMLNPIIYSLRNNDVKAAVRNLVSQKCFRR", "length": 319, "header": "tr|M0QW35-1|M0QW35_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR13C11 PE=3 SV=1 CANONICAL=M0QW35-1" }, "locus": { "chromosome": "8", "start_pos": 60259952, "end_pos": 60258996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039087.5", "url": "https://www.ensembl.org/id/ENSBTAT00000039087.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038889.4", "url": "https://www.ensembl.org/id/ENSBTAP00000038889.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": 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"uniprot_canonical_ac": "Q9NQN1-1", "protein_name": "Olfactory receptor 2S2", "gene_name": "OR2S2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKANETSPVMGFVLLRLSAHPELEKTFFVLILLMYLVILLGNGVLILVTILDSRLHTPMYFFLGNLSFLDICFTTSSVPLVLDSFLTPQETISFSACAVQMALSFAMAGTECLLLSMMAFDRYVAICNPLRYSVIMSKAAYMPMAASSWAIGGAASVVHTSLAIQLPFCGDNVINHFTCEILAVLKLACADISINVISMEVTNVIFLGVPVLFISFSYVFIITTILRIPSAEGRKKVFSTCSAHLTVVIVFYGTLFFMYGKPKSKDSMGADKEDLSDKLIPLFYGVVTPMLNPIIYSLRNKDVKAAVRRLLRPKGFTQ", "length": 319 }, "evidence": [ { "id": "M0QW35", "url": "https://omabrowser.org/oma/group/M0QW35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "M0QW35", "url": "https://www.uniprot.org/uniprotkb/M0QW35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-M0QW35-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 319, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-M0QW35-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/M0QW35" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "M0QW35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0QW35" }, { "id": "PS50262", "database": "PROSITE", "url": 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}, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "M0QW40", "url": "https://www.orthodb.org/?gene=M0QW40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "M0QW40", "url": "https://www.uniprot.org/uniprotkb/M0QW40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M0QW40-1", "url": "https://www.uniprot.org/uniprotkb/M0QW40-1", "database": "UniProtKB", "categories": [ 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"tr|M0QW40-1|M0QW40_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR13C7J PE=3 SV=2 CANONICAL=M0QW40-1" }, "locus": { "chromosome": "8", "start_pos": 60313119, "end_pos": 60306438, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055323.4", "url": "https://www.ensembl.org/id/ENSBTAT00000055323.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047613.3", "url": "https://www.ensembl.org/id/ENSBTAP00000047613.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0QW40", "url": "https://www.uniprot.org/uniprotkb/M0QW40" } ], "pmid": "" }, { "name": "olfactory receptor activity", 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"url": "https://www.uniprot.org/uniprotkb/M0QW40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-M0QW40-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-M0QW40-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/M0QW40" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "M0QW40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0QW40" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": 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to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377212" }, "gene_names": [ { "name": "OR4C174", "type": "recommended", "evidence": [ { "id": "M0QW42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ] }, { "name": "OR4C174", "type": "synonym", "evidence": [ { "id": "NP_001377212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377212" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 4 subfamily C member 174", "type": "synonym", "evidence": [ { "id": "M0QW42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0QW42/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4C46", "type": "synonym", "evidence": [ { "id": "NP_001377212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377212" } ] }, { "name": "olfactory receptor family 4 subfamily C member 174", "type": "synonym", "evidence": [ { "id": "NP_001377212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377212" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377212" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4C174", "url": "https://www.uniprot.org/uniprotkb/M0QW42", "locus": {} } ], "crossref": [ { "id": "M0QW42", "url": "https://alphafold.ebi.ac.uk/entry/M0QW42", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013156", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013156", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "781264", "url": "https://www.ncbi.nlm.nih.gov/gene/781264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FFFMPCI", "url": "https://omabrowser.org/oma/group/FFFMPCI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377212", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M0QW42-1", "url": "https://www.uniprot.org/uniprotkb/M0QW42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKHMENRNMTEFVLLGLTENPKMQKIVFAMFLVIYLTTVVANVLIVVTINVSSSLRSPMYFVLAHLSFVDACYSSVSTPKLIADSRYEKKTILFNGCMTQIFGEHFFGGAEIILLTVMAYDCYVAIYKPLHYTTIMNWWVCGLLVGVAWVGGFLHGFIQILFIFHLPFCGSNVINHFMCDLNPLLKLACTDTNTLGLFVAANSGLICLLNFFLLLVSYVAILYSPKTYSLEAGHKALSTCISHVTVVVLFFVPCTFVYMRPAATLPIDKAVAVFHTMITPMLNPLIYTLRNDQMKNAIKKLCSRKVI", "length": 307, "header": "tr|M0QW42-1|M0QW42_BOVIN Isoform 1 of Olfactory receptor family 4 subfamily C member 174 OS=Bos taurus OX=9913 GN=OR4C174 PE=3 SV=2 CANONICAL=M0QW42-1" }, "isoforms": [ { "isoform_ac": "M0QW42-1", "url": "https://www.uniprot.org/uniprotkb/M0QW42/entry", "sequence": { "sequence": "MKHMENRNMTEFVLLGLTENPKMQKIVFAMFLVIYLTTVVANVLIVVTINVSSSLRSPMYFVLAHLSFVDACYSSVSTPKLIADSRYEKKTILFNGCMTQIFGEHFFGGAEIILLTVMAYDCYVAIYKPLHYTTIMNWWVCGLLVGVAWVGGFLHGFIQILFIFHLPFCGSNVINHFMCDLNPLLKLACTDTNTLGLFVAANSGLICLLNFFLLLVSYVAILYSPKTYSLEAGHKALSTCISHVTVVVLFFVPCTFVYMRPAATLPIDKAVAVFHTMITPMLNPLIYTLRNDQMKNAIKKLCSRKVI", "length": 307, "header": "tr|M0QW42-1|M0QW42_BOVIN Isoform 1 of Olfactory receptor family 4 subfamily C member 174 OS=Bos taurus OX=9913 GN=OR4C174 PE=3 SV=2 CANONICAL=M0QW42-1" }, "locus": { "chromosome": "15", "start_pos": 392895, "end_pos": 391975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035247.6", "url": "https://www.ensembl.org/id/ENSBTAT00000035247.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047873.3", "url": "https://www.ensembl.org/id/ENSBTAP00000047873.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q8VF98-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c105", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIKNNVTEFVLLGLTQNLHLQKIVFVVFLVIYVFSVVGNLLIVITITNSQLLGYPMYYFLAYLSFIDACYSSVNTPKVIADSLHKRKSIKFNGCMTQVFAEHFIGGTEVILLTVMAYDRYVAICKPLHYATIMNRQLCNILVGVSWVGGFLHGGIQILFIIGLPFCGPNVIDHFMCDLNPLLDLACIDTHILGLFVAANSGFICLLNFLLLLVSYLVILNSLRSHSAEGRRKALSTCVSHITVVVLFFVPCIFVYMRPVATLPIDKAVTLFYTMITPMLNPLIYTLRNAQMKNAIWKLFSVKVQSDDK", "length": 309 }, "evidence": [ { "id": "M0QW42", "url": "https://omabrowser.org/oma/group/M0QW42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "M0QW42", "url": "https://www.uniprot.org/uniprotkb/M0QW42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-M0QW42-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-M0QW42-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/M0QW42" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "M0QW42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M0QW42" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 50, "end_pos": 52 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377089" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "M5FK71", "url": "https://www.uniprot.org/uniprotkb/M5FK71#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "M5FK71", "url": "https://www.uniprot.org/uniprotkb/M5FK71" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1F1E", "url": "https://www.uniprot.org/uniprotkb/M5FK71", "locus": { "chromosome": "25", "start_pos": 2675684, "end_pos": 2674740, "strand": "-", "evidence": [ 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"id": "M5FK71-1", "url": "https://www.uniprot.org/uniprotkb/M5FK71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEANQSRVSEFLLLGLSRQPQQQQQLLFLLFLTMYLATVLGNLLILLAISMDSHLHIPMYFFLCNLSFVDTYFSSTTVPKVLANHVLRSHTISFSECLTQMYFVFMFMDMDNFLLAVIAYDRFVAVCHPLHYSAKMTPQLCALLVTGSWVTASLDMLLHTLLMARLSFCADNAIPHFFCDVTPLLKLSCSDTHLNEVVILTEGALIMITPFVCILVSYVLITCAVLRIPSTKGRWKAFSTCGSHLAVVFLFYGTIIFLYFNPLSSHAAETDVAAGVMFSVVTPMLNPFIYSLRNQDIKGALGKVIAMKFFSAQ", "length": 314, "header": "tr|M5FK71-1|M5FK71_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1F1E PE=3 SV=1 CANONICAL=M5FK71-1" }, "isoforms": [ { "isoform_ac": "M5FK71-1", "url": "https://www.uniprot.org/uniprotkb/M5FK71/entry", "sequence": { "sequence": 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"Protein Classification", "Other" ] }, { "id": "NP_783634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_783634", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "O02775", "url": "https://www.uniprot.org/uniprotkb/O02775", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O02775-1", "url": "https://www.uniprot.org/uniprotkb/O02775-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLHHLLLTLLFLVLSAGSGFTQGISNPLSCRLNRGICVPIRCPGNLRQIGTCFTPSVKCCRWR", "length": 64, "header": "sp|O02775-1|EAP_BOVIN Isoform 1 of Enteric beta-defensin OS=Bos taurus OX=9913 GN=EBD PE=2 SV=1 CANONICAL=O02775-1" }, "isoforms": [ { "isoform_ac": "O02775-1", "url": "https://www.uniprot.org/uniprotkb/O02775/entry#O02775-1", "sequence": { "sequence": "MRLHHLLLTLLFLVLSAGSGFTQGISNPLSCRLNRGICVPIRCPGNLRQIGTCFTPSVKCCRWR", "length": 64, "header": "sp|O02775-1|EAP_BOVIN Isoform 1 of Enteric beta-defensin OS=Bos taurus OX=9913 GN=EBD PE=2 SV=1 CANONICAL=O02775-1" }, "locus": { "chromosome": "27", "start_pos": 7180318, "end_pos": 7178654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139783.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139783.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106367.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106367.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The synthetic peptides bovine enteric \u03b2-defensin (EBD), bovine neutrophil \u03b2-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells.", "journal": "Veterinary immunology and immunopathology", "date": "2011-09-15", "authors": "Mackenzie-Dyck Sarah, Attah-Poku Sam, Juillard Veronique, Babiuk Lorne A, van Drunen Littel-van den Hurk Sylvia", "evidence": [ { "database": "RefSeq", "id": "NP_783634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_783634" } ], "reference": [ { "type": "PubMed", "id": "21764462", "url": "https://glygen.org/publication/PubMed/21764462" } ] }, { "title": "Expression of antimicrobial peptides by bovine endothelial cells.", "journal": "Cellular immunology", "date": "2012-11", "authors": "Alva-Murillo Nayeli, T\u00e9llez-P\u00e9rez Ana D, Sagrero-Cisneros Eduardo, L\u00f3pez-Meza Joel E, Ochoa-Zarzosa Alejandra", "evidence": [ { "database": "RefSeq", "id": "NP_783634", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_783634" } ], "reference": [ { "type": "PubMed", "id": "23298865", "url": "https://glygen.org/publication/PubMed/23298865" } ] }, { "title": "Somatic cell mapping of beta-defensin genes to cattle syntenic group U25 and fluorescence in situ localization to chromosome 27.", "journal": "Mamm. Genome", "date": "1995", "authors": "Gallagher D S, Ryan A M, Diamond G, Bevins C L, Womack J E", "evidence": [ { "database": "UniProtKB", "id": "O02775", "url": "https://www.uniprot.org/uniprotkb/O02775" } ], "reference": [ { "type": "PubMed", "id": "8589529", "url": "https://glygen.org/publication/PubMed/8589529" } ] }, { "title": "Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection.", "journal": "Infect. Immun.", "date": "1998", "authors": "Tarver A P, Clark D P, Diamond G, Russell J P, Erdjument-Bromage H, Tempst P, Cohen K S, Jones D E, Sweeney R W, Wines M, Hwang S, Bevins C L", "evidence": [ { "database": "UniProtKB", "id": "O02775", "url": "https://www.uniprot.org/uniprotkb/O02775" } ], "reference": [ { "type": "PubMed", "id": "9488394", "url": "https://glygen.org/publication/PubMed/9488394" } ] } ], "pathway": [ { "id": "bta:281743", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281743", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LJX0-1", "protein_name": "Beta-defensin 4-like", "gene_name": "LOC100767221", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRIHYLLLTFLLVLLSPFSAFTQRIKNPVTCLTNGGICWGACRGNFRQIGTCGIPKVRCCKRR", "length": 63 }, "evidence": [ { "id": "O02775", "url": "https://omabrowser.org/oma/group/O02775/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O15263-1", "protein_name": "Defensin beta 4A", "gene_name": "DEFB4B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP", "length": 64 }, "evidence": [ { "id": "O02775", "url": "https://omabrowser.org/oma/group/O02775/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88514-1", "protein_name": "Beta-defensin 4", "gene_name": "Defb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRIHYLLFSFLLVLLSPLSAFTQSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK", "length": 63 }, "evidence": [ { "id": "O02775", "url": "https://omabrowser.org/oma/group/O02775/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTL0-1", "protein_name": "Beta-defensin 3", "gene_name": "Defb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. 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"https://www.uniprot.org/uniprotkb/O19104" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "O19104", "url": "https://www.uniprot.org/uniprotkb/O19104" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "O19104", "url": "https://www.uniprot.org/uniprotkb/O19104" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "O19104", "url": "https://www.uniprot.org/uniprotkb/O19104" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"Thyroliberin receptor", "type": "synonym", "evidence": [ { "id": "O46639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46639/entry#names_and_taxonomy" } ] }, { "name": "thyroliberin receptor", "type": "synonym", "evidence": [ { "id": "NP_776628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776628" } ] }, { "name": "thyrotropin-releasing hormone receptor", "type": "synonym", "evidence": [ { "id": "NP_776628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776628" } ] } ], "function": [ { "annotation": "Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.", "evidence": [ { "database": "UniProtKB", "id": "O46639", "url": "https://www.uniprot.org/uniprotkb/O46639#function" }, { "database": "UniProtKB", "id": "P34981", "url": "https://www.uniprot.org/uniprotkb/P34981#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "O46639", "url": "https://www.uniprot.org/uniprotkb/O46639" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRHR", "url": "https://www.uniprot.org/uniprotkb/O46639", "locus": { "chromosome": "14", "start_pos": 55316939, "end_pos": 55363175, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019997", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281549", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281549", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCKQKPA", "url": "https://omabrowser.org/oma/group/NCKQKPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "O46639", "url": "https://www.orthodb.org/?gene=O46639", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46061:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46061:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_776628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776628", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "O46639", "url": "https://www.uniprot.org/uniprotkb/O46639", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O46639-1", "url": "https://www.uniprot.org/uniprotkb/O46639-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENETGSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVVSCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSNMWKNDSTHQNKNLNSKTSNRYFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPVEKPANYSVALSYSVIKESDRFSTELDDVTVTDTYLSATKVSFDDTCLASEITFNQS", "length": 398, "header": "sp|O46639-1|TRHR_BOVIN Isoform 1 of Thyrotropin-releasing hormone receptor OS=Bos taurus OX=9913 GN=TRHR PE=3 SV=1 CANONICAL=O46639-1" }, "isoforms": [ { "isoform_ac": "O46639-1", "url": "https://www.uniprot.org/uniprotkb/O46639/entry#O46639-1", "sequence": { "sequence": "MENETGSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVVSCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSNMWKNDSTHQNKNLNSKTSNRYFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPVEKPANYSVALSYSVIKESDRFSTELDDVTVTDTYLSATKVSFDDTCLASEITFNQS", "length": 398, "header": "sp|O46639-1|TRHR_BOVIN Isoform 1 of Thyrotropin-releasing hormone receptor OS=Bos taurus OX=9913 GN=TRHR PE=3 SV=1 CANONICAL=O46639-1" }, "locus": { "chromosome": "14", "start_pos": 55362360, "end_pos": 55317462, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026634.3", "url": "https://www.ensembl.org/id/ENSBTAT00000026634.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026634.1", "url": "https://www.ensembl.org/id/ENSBTAP00000026634.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 10, "start_aa": "Asn", "end_pos": 10, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn10", "evidence": [ { "id": "O46639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46639#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3, "start_aa": "Asn", "end_pos": 3, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3", "evidence": [ { "id": "O46639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46639#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Molecular cloning of bovine thyrotropin-releasing hormone receptor gene.", "journal": "J. Vet. Med. 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J.", "date": "1986", "authors": "Kingston I B, Anderson S", "evidence": [ { "database": "UniProtKB", "id": "P04815", "url": "https://www.uniprot.org/uniprotkb/P04815" } ], "reference": [ { "type": "PubMed", "id": "2420326", "url": "https://glygen.org/publication/PubMed/2420326" } ] }, { "title": "Sequences of the genes and polypeptide precursors for two bovine protease inhibitors.", "journal": "J. Mol. Biol.", "date": "1987", "authors": "Creighton T E, Charles I G", "evidence": [ { "database": "UniProtKB", "id": "P04815", "url": "https://www.uniprot.org/uniprotkb/P04815" } ], "reference": [ { "type": "PubMed", "id": "2441071", "url": "https://glygen.org/publication/PubMed/2441071" } ] }, { "title": "Biosynthesis, processing, and evolution of bovine pancreatic trypsin inhibitor.", "journal": "Cold Spring Harb. Symp. Quant. 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GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell-cell interactions. The transcript for this gene is bicistronic. The downstream open reading frame encodes this GPI-GnT complex protein, while the upstream open reading frame encodes a protein with unknown function, as represented by GeneID:100996942. [provided by RefSeq, Aug 2012].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257875" }, "gene_names": [ { "name": "PIGY", "type": "recommended", "evidence": [ { "id": "P0C1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C1N9" } ] }, { "name": "PIG-Y", "type": "synonym", "evidence": [ { "id": "NP_001257875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257875" } ] }, { "name": "PIGY", "type": "synonym", "evidence": [ { "id": "NP_001257875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257875" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y", "type": "recommended", "evidence": [ { "id": "P0C1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C1N9/entry#names_and_taxonomy" } ] }, { "name": "PIG-Y", "type": "synonym", "evidence": [ { "id": "P0C1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C1N9/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylinositol-glycan biosynthesis class Y protein", "type": "synonym", "evidence": [ { "id": "P0C1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C1N9/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylinositol N-acetylglucosaminyltransferase subunit Y", "type": "synonym", "evidence": [ { "id": "NP_001257875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257875" } ] }, { "name": "phosphatidylinositol-glycan biosynthesis class Y protein", "type": "synonym", "evidence": [ { "id": "NP_001257875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257875" } ] } ], "function": [ { "annotation": "Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the catalytic subunit PIGA.", "evidence": [ { "database": "UniProtKB", "id": "P0C1N9", "url": "https://www.uniprot.org/uniprotkb/P0C1N9#function" }, { "database": "UniProtKB", "id": "Q3MUY2", "url": "https://www.uniprot.org/uniprotkb/Q3MUY2#function" } ] }, { "annotation": "The protein encoded by this gene is part of the GPI-N-acetylglucosaminyltransferase (GIP-GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell-cell interactions. The transcript for this gene is bicistronic. The downstream open reading frame encodes this GPI-GnT complex protein, while the upstream open reading frame encodes a protein with unknown function, as represented by GeneID:100996942. [provided by RefSeq, Aug 2012].", "evidence": [ { "database": "RefSeq", "id": "NP_001257875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257875" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P0C1N9", "url": "https://www.uniprot.org/uniprotkb/P0C1N9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PIGY", "url": "https://www.uniprot.org/uniprotkb/P0C1N9", "locus": {} } ], "crossref": [ { "id": "P0C1N9", "url": "https://alphafold.ebi.ac.uk/entry/P0C1N9", "database": "AlphaFoldDB", "categories": [] }, { "id": "514374", "url": "https://www.ncbi.nlm.nih.gov/gene/514374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514374", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514374", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR39235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39235:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39235:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001257875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257875", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P0C1N9", "url": "https://www.uniprot.org/uniprotkb/P0C1N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0C1N9-1", "url": "https://www.uniprot.org/uniprotkb/P0C1N9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLSLPMLTVLIPLVSLAGLFYSASVEDDFPQGCTSTTSLCFYSLLLPITIPVYVFFHLWTWMGIKLFRHN", "length": 71, "header": "sp|P0C1N9-1|PIGY_BOVIN Isoform 1 of Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y OS=Bos taurus OX=9913 GN=PIGY PE=3 SV=1 CANONICAL=P0C1N9-1" }, "isoforms": [ { "isoform_ac": "P0C1N9-1", "url": "https://www.uniprot.org/uniprotkb/P0C1N9/entry#P0C1N9-1", "sequence": { "sequence": "MFLSLPMLTVLIPLVSLAGLFYSASVEDDFPQGCTSTTSLCFYSLLLPITIPVYVFFHLWTWMGIKLFRHN", "length": 71, "header": "sp|P0C1N9-1|PIGY_BOVIN Isoform 1 of Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y OS=Bos taurus OX=9913 GN=PIGY PE=3 SV=1 CANONICAL=P0C1N9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514374", "name": "", "url": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P0C7I2-1", "uniprot_ac": "P0C7I2", "uniprot_id": "IGIP_BOVIN", "mass": { "chemical_mass": 5072.0, "monoisotopic_mass": 5072.0 }, "refseq": { "ac": "NP_991340", "name": "IgA-inducing protein precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991340" }, "gene_names": [ { "name": "IGIP", "type": "recommended", "evidence": [ { "id": "P0C7I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C7I2" } ] }, { "name": "IGIP", "type": "synonym", "evidence": [ { "id": "NP_991340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991340" } ] } ], "protein_names": [ { "name": "IgA-inducing protein", "type": "recommended", "evidence": [ { "id": "P0C7I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C7I2/entry#names_and_taxonomy" } ] }, { "name": "IgA regulatory protein", "type": "synonym", "evidence": [ { "id": "NP_991340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991340" } ] }, { "name": "IgA-inducing protein precursor", "type": "synonym", "evidence": [ { "id": "NP_991340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991340" } ] } ], "function": [ { "annotation": "Enhances IgA secretion from B-cells stimulated via CD40.", "evidence": [ { "database": "UniProtKB", "id": "P0C7I2", "url": "https://www.uniprot.org/uniprotkb/P0C7I2#function" } ] }, { "annotation": "IgA-inducing protein IGIP regulates IgA by acting as a switch or differentiation factor and is expressed in a variety of lymphoid and nonlymphoid tissues.", "evidence": [ { "database": "RefSeq", "id": "NP_991340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991340" }, { "database": "PubMed", "id": "12874223", "url": "https://glygen.org/publication/PubMed/12874223" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P0C7I2", "url": "https://www.uniprot.org/uniprotkb/P0C7I2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IGIP", "url": "https://www.uniprot.org/uniprotkb/P0C7I2", "locus": {} } ], "crossref": [ { "id": "P0C7I2", "url": "https://alphafold.ebi.ac.uk/entry/P0C7I2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000025226", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025226", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "404059", "url": "https://www.ncbi.nlm.nih.gov/gene/404059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:404059", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:404059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P0C7I2", "url": "https://www.orthodb.org/?gene=P0C7I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39224:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39224:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_991340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991340", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P0C7I2", "url": "https://www.uniprot.org/uniprotkb/P0C7I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0C7I2-1", "url": "https://www.uniprot.org/uniprotkb/P0C7I2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKRSVSGCNITILAVVFSHLSAGNSPCGNQANVLCISRLEFVQYQS", "length": 47, "header": "sp|P0C7I2-1|IGIP_BOVIN Isoform 1 of IgA-inducing protein OS=Bos taurus OX=9913 GN=IGIP PE=1 SV=1 CANONICAL=P0C7I2-1" }, "isoforms": [ { "isoform_ac": "P0C7I2-1", "url": "https://www.uniprot.org/uniprotkb/P0C7I2/entry#P0C7I2-1", "sequence": { "sequence": "MKKRSVSGCNITILAVVFSHLSAGNSPCGNQANVLCISRLEFVQYQS", "length": 47, "header": "sp|P0C7I2-1|IGIP_BOVIN Isoform 1 of IgA-inducing protein OS=Bos taurus OX=9913 GN=IGIP PE=1 SV=1 CANONICAL=P0C7I2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification and characterization of a novel regulatory factor: IgA-inducing protein.", "journal": "J. Immunol.", "date": "2003", "authors": "Austin Amy S, Haas Karen M, Naugler Sasha M, Bajer Anna A, Garcia-Tapia David, Estes D Mark", "evidence": [ { "database": "UniProtKB", "id": "P0C7I2", "url": "https://www.uniprot.org/uniprotkb/P0C7I2" }, { "database": "RefSeq", "id": "NP_991340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_991340" } ], "reference": [ { "type": "PubMed", "id": "12874223", "url": "https://glygen.org/publication/PubMed/12874223" } ] } ], "pathway": [ { "id": "bta:404059", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:404059", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P0C7I2", "url": "https://www.uniprot.org/uniprotkb/P0C7I2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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"MKEPRIFPRERPTPWTRAPLPPRGRLDGSLGPQGGPVLNTGHPLGMNSDPFLMASSSLGGNLAPFPRNPSPFPTSSGSLASNPAPFPAGARDPGLASFPRGMNPTSTGAVSFPRPGGLLGPSPGSTLNPRAGALPGPGPLSNPRLGSLPGPGPVSNPRPSGLLGTGPDPRSGGPMGPGSGPSLRAGVLLTPGNGPPNPRPVGLGPGPSPNLRSGFVGTNPAPRSSMFPGPGLGPNPRSSGLGPGLGPNPRAGGLGPGPNLDARAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGANSASFSQASGNMGTSPSSMARLPGPIGPNSGPGSRGIGLPGPNPSPLSRAPGPVGPNSAHFARPAGPMGVNANPFPRGTGSGGLNPAAFSQSSNTLASNPINFQRSAGLQGSSPAVFPRASGPLGPNPANFPRATGLQGPSPATFPRSIGPLGPGQVTFPRPAPRPLGSSPAGPVGINPAPFARPTGTLGVNPASFPRMNGPVSKTLVPFPRVGSLPGTNPAAFPRPGGPMAAMYPNGMLPP", "length": 540, "header": "sp|P0CG10-1|DERPC_BOVIN Isoform 1 of Decreased expression in renal and prostate cancer protein OS=Bos taurus OX=9913 GN=DERPC PE=2 SV=1 CANONICAL=P0CG10-1" }, "isoforms": [ { "isoform_ac": "P0CG10-1", "url": "https://www.uniprot.org/uniprotkb/P0CG10/entry#P0CG10-1", "sequence": { "sequence": "MKEPRIFPRERPTPWTRAPLPPRGRLDGSLGPQGGPVLNTGHPLGMNSDPFLMASSSLGGNLAPFPRNPSPFPTSSGSLASNPAPFPAGARDPGLASFPRGMNPTSTGAVSFPRPGGLLGPSPGSTLNPRAGALPGPGPLSNPRLGSLPGPGPVSNPRPSGLLGTGPDPRSGGPMGPGSGPSLRAGVLLTPGNGPPNPRPVGLGPGPSPNLRSGFVGTNPAPRSSMFPGPGLGPNPRSSGLGPGLGPNPRAGGLGPGPNLDARAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGANSASFSQASGNMGTSPSSMARLPGPIGPNSGPGSRGIGLPGPNPSPLSRAPGPVGPNSAHFARPAGPMGVNANPFPRGTGSGGLNPAAFSQSSNTLASNPINFQRSAGLQGSSPAVFPRASGPLGPNPANFPRATGLQGPSPATFPRSIGPLGPGQVTFPRPAPRPLGSSPAGPVGINPAPFARPTGTLGVNPASFPRMNGPVSKTLVPFPRVGSLPGTNPAAFPRPGGPMAAMYPNGMLPP", "length": 540, "header": "sp|P0CG10-1|DERPC_BOVIN Isoform 1 of Decreased expression in renal and prostate cancer protein OS=Bos taurus OX=9913 GN=DERPC PE=2 SV=1 CANONICAL=P0CG10-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [ { "start_pos": 313, "end_pos": 313, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P0CG10", "url": "https://www.uniprot.org/uniprotkb/P0CG10" } ], "site_lbl": "Ser313" }, { "start_pos": 439, "end_pos": 439, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P0CG10", "url": "https://www.uniprot.org/uniprotkb/P0CG10" } ], "site_lbl": "Ser439" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:618186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618186", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P0CG10", "url": "https://www.uniprot.org/uniprotkb/P0CG10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P0CG10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 540, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P0CG10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P0CG10" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 13 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 313, 439 ], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P0CG11-1", "uniprot_ac": "P0CG11", "uniprot_id": "CTF8_BOVIN", "mass": { "chemical_mass": 13161.0, "monoisotopic_mass": 13161.0 }, "refseq": { "ac": "NP_001108441", "name": "chromosome transmission fidelity protein 8 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" }, "gene_names": [ { "name": "CHTF8", "type": "recommended", "evidence": [ { "id": "P0CG11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ] }, { "name": "CHTF8", "type": "synonym", "evidence": [ { "id": "NP_001108441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" } ] }, { "name": "CTF8", "type": "synonym", "evidence": [ { "id": "NP_001108441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" }, { "id": "P0CG11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ] }, { "name": "DERPC", "type": "synonym", "evidence": [ { "id": "NP_001108441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" } ] } ], "protein_names": [ { "name": "Chromosome transmission fidelity protein 8 homolog", "type": "recommended", "evidence": [ { "id": "P0CG11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG11/entry#names_and_taxonomy" } ] }, { "name": "CTF8, chromosome transmission fidelity factor 8 homolog", "type": "synonym", "evidence": [ { "id": "NP_001108441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" } ] }, { "name": "chromosome transmission fidelity factor 8 homolog", "type": "synonym", "evidence": [ { "id": "NP_001108441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" } ] }, { "name": "chromosome transmission fidelity protein 8 homolog", "type": "synonym", "evidence": [ { "id": "NP_001108441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" } ] }, { "name": "protein DERPC", "type": "synonym", "evidence": [ { "id": "NP_001108441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441" } ] } ], "function": [ { "annotation": "Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DSCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair, recombination and chromosome cohesion reactions with replication fork progression (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11#function" }, { "database": "UniProtKB", "id": "P0CG13", "url": "https://www.uniprot.org/uniprotkb/P0CG13#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHTF8", "url": "https://www.uniprot.org/uniprotkb/P0CG11", "locus": {} } ], "crossref": [ { "id": "P0CG11", "url": "https://alphafold.ebi.ac.uk/entry/P0CG11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001698", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618186", "url": "https://www.ncbi.nlm.nih.gov/gene/618186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618186", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P0CG11", "url": "https://www.orthodb.org/?gene=P0CG11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28605:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28605:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09696", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-174411", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001108441", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108441", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0CG11-1", "url": "https://www.uniprot.org/uniprotkb/P0CG11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQIVISSAGAGGLAEWVLMELQGEIEARHSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKIIHLEKPFAVLVKHTPGEQDCDELGCESGTRYLVTALIKNKILFKTRPKPIITNVPKKV", "length": 121, "header": "sp|P0CG11-1|CTF8_BOVIN Isoform 1 of Chromosome transmission fidelity protein 8 homolog OS=Bos taurus OX=9913 GN=CHTF8 PE=3 SV=1 CANONICAL=P0CG11-1" }, "isoforms": [ { "isoform_ac": "P0CG11-1", "url": "https://www.uniprot.org/uniprotkb/P0CG11/entry#P0CG11-1", "sequence": { "sequence": "MVQIVISSAGAGGLAEWVLMELQGEIEARHSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKIIHLEKPFAVLVKHTPGEQDCDELGCESGTRYLVTALIKNKILFKTRPKPIITNVPKKV", "length": 121, "header": "sp|P0CG11-1|CTF8_BOVIN Isoform 1 of Chromosome transmission fidelity protein 8 homolog OS=Bos taurus OX=9913 GN=CHTF8 PE=3 SV=1 CANONICAL=P0CG11-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618186", "resource": "KEGG Pathway" }, { "id": "R-BTA-174411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174411", "resource": "Reactome", "description": "Polymerase switching on the C-strand of the telomere" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ], "pmid": "" }, { "name": "positive regulation of DNA-directed DNA polymerase activity", "id": "GO:1900264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900264", "evidence": [ { "database": "UniProtKB", "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Ctf18 RFC-like complex", "id": "GO:0031390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031390", "evidence": [ { "database": "UniProtKB", "id": "P0CG11", "url": "https://www.uniprot.org/uniprotkb/P0CG11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P0CG11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 121, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P0CG11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P0CG11" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P0CG25-1", "uniprot_ac": "P0CG25", "uniprot_id": "EFCC1_BOVIN", "mass": { "chemical_mass": 64552.0, "monoisotopic_mass": 64552.0 }, "refseq": { "ac": "NP_001140164", "name": "EF-hand and coiled-coil domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001140164" }, "gene_names": [ { "name": "EFCC1", "type": "recommended", "evidence": [ { "id": "P0CG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG25" } ] }, { "name": "CCDC48", "type": "synonym", "evidence": [ { "id": "NP_001140164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001140164" }, { "id": "P0CG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG25" } ] }, { "name": "EFCC1", "type": "synonym", "evidence": [ { "id": "NP_001140164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001140164" } ] } ], "protein_names": [ { "name": "EF-hand and coiled-coil domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "P0CG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG25/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 48", "type": "synonym", "evidence": [ { "id": "NP_001140164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001140164" }, { "id": "P0CG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG25/entry#names_and_taxonomy" } ] }, { "name": "EF-hand and coiled-coil domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001140164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001140164" } ] }, { "name": "coiled-coil domain containing 48", "type": "synonym", "evidence": [ { "id": "NP_001140164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001140164" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P0CG25", "url": "https://www.uniprot.org/uniprotkb/P0CG25" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EFCC1", "url": "https://www.uniprot.org/uniprotkb/P0CG25", "locus": { "chromosome": "22", "start_pos": 59009178, "end_pos": 58979773, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005922", "url": "https://www.ensembl.org/id/ENSBTAG00000005922" } ] } } ], "crossref": [ { "id": "P0CG25", "url": "https://alphafold.ebi.ac.uk/entry/P0CG25", "database": "AlphaFoldDB", "categories": [] }, { "id": "617677", "url": "https://www.ncbi.nlm.nih.gov/gene/617677", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617677", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617677", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P0CG25", "url": "https://www.orthodb.org/?gene=P0CG25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001140164", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001140164", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P0CG25", "url": "https://www.uniprot.org/uniprotkb/P0CG25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P0CG25-1", "url": "https://www.uniprot.org/uniprotkb/P0CG25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGAASDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDSRGAGRLPRADFRALCAVLGLRFEGAAAPGEASEDTAAGDTNSGDVISGDAAAGEAAEWDEDAEEEARLALRAEPPELTFRQFHARLCGYFGTRAGPRLPRGALSEHIETQIRLRRPRRRRRRAARPPGPDGGPDGERLARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQAGAQEAARGEPEAAARELRQARGALAAAEAQAGRLRRGQAEVRRRAEEARAAVLRSLGRVRELEALARQMPGLQRGLRLLEGELRRYRSEGTQLPGPSRASPEPDTKSSEPEDGEARGPEPPPEGAWGSGNSPASRPPGPARASPGLDEQLFRSVEGQAASDEEDDREKWQEAQRLPAEVTALLAGLSGCGSGCDDQTAKKLMTYCSHLGGANHAHTLGELETCVAMLVEQLGSRGCGAKTLRTPEEEAELQRKVGENESLRQELQMVEAERVRLSLLEEKLEDVLGLLQRLRDLNISKKALGKILLSTLDACRDPAHDGPSGPLAVLEALHRALAGCELLRREPSAPASTAPALPHSFPISG", "length": 597, "header": "sp|P0CG25-1|EFCC1_BOVIN Isoform 1 of EF-hand and coiled-coil domain-containing protein 1 OS=Bos taurus OX=9913 GN=EFCC1 PE=2 SV=1 CANONICAL=P0CG25-1" }, "isoforms": [ { "isoform_ac": "P0CG25-1", "url": "https://www.uniprot.org/uniprotkb/P0CG25/entry#P0CG25-1", "sequence": { "sequence": "MEGAASDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDSRGAGRLPRADFRALCAVLGLRFEGAAAPGEASEDTAAGDTNSGDVISGDAAAGEAAEWDEDAEEEARLALRAEPPELTFRQFHARLCGYFGTRAGPRLPRGALSEHIETQIRLRRPRRRRRRAARPPGPDGGPDGERLARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQAGAQEAARGEPEAAARELRQARGALAAAEAQAGRLRRGQAEVRRRAEEARAAVLRSLGRVRELEALARQMPGLQRGLRLLEGELRRYRSEGTQLPGPSRASPEPDTKSSEPEDGEARGPEPPPEGAWGSGNSPASRPPGPARASPGLDEQLFRSVEGQAASDEEDDREKWQEAQRLPAEVTALLAGLSGCGSGCDDQTAKKLMTYCSHLGGANHAHTLGELETCVAMLVEQLGSRGCGAKTLRTPEEEAELQRKVGENESLRQELQMVEAERVRLSLLEEKLEDVLGLLQRLRDLNISKKALGKILLSTLDACRDPAHDGPSGPLAVLEALHRALAGCELLRREPSAPASTAPALPHSFPISG", "length": 597, "header": "sp|P0CG25-1|EFCC1_BOVIN Isoform 1 of EF-hand and coiled-coil domain-containing protein 1 OS=Bos taurus OX=9913 GN=EFCC1 PE=2 SV=1 CANONICAL=P0CG25-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617677", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617677", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "P0CG25", "url": "https://www.uniprot.org/uniprotkb/P0CG25" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P0CG25", "url": "https://www.uniprot.org/uniprotkb/P0CG25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P0CG25", "url": "https://www.uniprot.org/uniprotkb/P0CG25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P0CG25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 597, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P0CG25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P0CG25" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "P0CG25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0CG25" }, { "id": "PRU00448", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00448" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000255", "start_pos": 43, "end_pos": 78, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 530, "end_pos": 532 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P10462-1", "uniprot_ac": "P10462", "uniprot_id": "S10A2_BOVIN", "mass": { "chemical_mass": 10893.0, "monoisotopic_mass": 10893.0 }, "refseq": { "ac": "NP_001029539", "name": "protein S100-A2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029539" }, "gene_names": [ { "name": "S100A2", "type": "recommended", "evidence": [ { "id": "P10462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10462" } ] }, { "name": "S100A2", "type": "synonym", "evidence": [ { "id": "NP_001029539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029539" } ] } ], "protein_names": [ { "name": "Protein S100-A2", "type": "recommended", "evidence": [ { "id": "P10462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10462/entry#names_and_taxonomy" } ] }, { "name": "Protein S-100L", "type": "synonym", "evidence": [ { "id": "P10462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10462/entry#names_and_taxonomy" } ] }, { "name": "S100 calcium-binding protein A2", "type": "synonym", "evidence": [ { "id": "P10462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10462/entry#names_and_taxonomy" } ] }, { "name": "protein S100-A2", "type": "synonym", 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May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. 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Biol. Chem.", "date": "2005", "authors": "Jeppesen Mads Gravers, Navratil Tomas, Spremulli Linda Lucy, Nyborg Jens", "evidence": [ { "database": "UniProtKB", "id": "P43896", "url": "https://www.uniprot.org/uniprotkb/P43896" }, { "database": "RefSeq", "id": "NP_776629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776629" } ], "reference": [ { "type": "PubMed", "id": "15557323", "url": "https://glygen.org/publication/PubMed/15557323" } ] }, { "title": "Analysis of the functional consequences of lethal mutations in mitochondrial translational elongation factors.", "journal": "Biochimica et biophysica acta", "date": "2010", "authors": "Akama Kenta, Christian Brooke E, Jones Christie N, Ueda Takuya, Takeuchi Nono, Spremulli Linda L", "evidence": [ { "database": "RefSeq", "id": "NP_776629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776629" } ], "reference": [ { "type": "PubMed", "id": "20435138", "url": "https://glygen.org/publication/PubMed/20435138" } ] }, { "title": "Bovine mitochondrial protein synthesis elongation factors. 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reproduction", "date": "2009-10", "authors": "Ulbrich Susanne E, Frohlich Thomas, Schulke Katy, Englberger Eva, Waldschmitt Nadine, Arnold Georg J, Reichenbach Horst-Dieter, Reichenbach Myriam, Wolf Eckhard, Meyer Heinrich H D, Bauersachs Stefan", "evidence": [ { "database": "RefSeq", "id": "NP_777222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777222" } ], "reference": [ { "type": "PubMed", "id": "19494250", "url": "https://glygen.org/publication/PubMed/19494250" } ] }, { "title": "Crosstalk between uterine serpin (SERPINA14) and pregnancy-associated glycoproteins at the fetal-maternal interface in pregnant dairy heifers experimentally infected with Neospora caninum.", "journal": "Theriogenology", "date": "2016-08", "authors": "Serrano-P\u00e9rez B, Hansen P J, Mur-Novales R, Garc\u00eda-Ispierto I, de Sousa N M, Beckers J F, Almer\u00eda S, L\u00f3pez-Gatius F", "evidence": [ { "database": "RefSeq", "id": "NP_777222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777222" } ], 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U.S.A.", "date": "1996", "authors": "Mathialagan N, Hansen T R", "evidence": [ { "database": "UniProtKB", "id": "P46201", "url": "https://www.uniprot.org/uniprotkb/P46201" } ], "reference": [ { "type": "PubMed", "id": "8942989", "url": "https://glygen.org/publication/PubMed/8942989" } ] } ], "pathway": [ { "id": "bta:286871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:286871", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "P46201", "url": "https://www.uniprot.org/uniprotkb/P46201" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { 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"evidence": [ { "database": "UniProtKB", "id": "P79103", "url": "https://www.uniprot.org/uniprotkb/P79103" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPS4", "url": "https://www.uniprot.org/uniprotkb/P79103", "locus": {} } ], "crossref": [ { "id": "P79103", "url": "https://alphafold.ebi.ac.uk/entry/P79103", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018800", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018800", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00165", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00165", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614241", "url": "https://www.ncbi.nlm.nih.gov/gene/614241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614241", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614241", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHIQLNL", "url": "https://omabrowser.org/oma/group/GHIQLNL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P79103", "url": "https://www.orthodb.org/?gene=P79103", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11581", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11581", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11581:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11581:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72689", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001030522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030522", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P79103", "url": "https://www.uniprot.org/uniprotkb/P79103", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P79103-1", "url": "https://www.uniprot.org/uniprotkb/P79103-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263, "header": "sp|P79103-1|RS4_BOVIN Isoform 1 of Small ribosomal subunit protein eS4 OS=Bos taurus OX=9913 GN=RPS4 PE=2 SV=3 CANONICAL=P79103-1" }, "isoforms": [ { "isoform_ac": "P79103-1", "url": "https://www.uniprot.org/uniprotkb/P79103/entry#P79103-1", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263, "header": "sp|P79103-1|RS4_BOVIN Isoform 1 of Small ribosomal subunit protein eS4 OS=Bos taurus OX=9913 GN=RPS4 PE=2 SV=3 CANONICAL=P79103-1" }, "locus": { "chromosome": "X", "start_pos": 78404633, "end_pos": 78400295, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025024.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025024.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025024.4", "url": "https://www.ensembl.org/id/ENSBTAP00000025024.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.", "journal": "Genomics", "date": "1996", "authors": "Omoe K, Endo A", "evidence": [ { "database": "UniProtKB", "id": "P79103", "url": "https://www.uniprot.org/uniprotkb/P79103" } ], "reference": [ { "type": "PubMed", "id": "8808278", "url": "https://glygen.org/publication/PubMed/8808278" } ] } ], "pathway": [ { "id": "bta:614241", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614241", "resource": "KEGG Pathway" }, { "id": "R-BTA-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-BTA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-BTA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-BTA-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-BTA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-BTA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-BTA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-BTA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-BTA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-BTA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-BTA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P0CX35-1", "protein_name": "Small ribosomal subunit protein eS4A", "gene_name": "RPS4A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL", "length": 261 }, "evidence": [ { "id": "P79103", "url": "https://omabrowser.org/oma/group/P79103/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX36-1", "protein_name": "Small ribosomal subunit protein eS4B", "gene_name": "RPS4B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL", "length": 261 }, "evidence": [ { "id": "P79103", "url": "https://omabrowser.org/oma/group/P79103/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P41042-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "RpS4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARGPKKHLKRLAAPKAWMLDKLGGVFAPRPSTGPHKLRESLPLLIFLRNRLKYALNGAEVTKIVMQRLVKVDGKVRTDPTYPAGYMDVITLEKTGEFFRLVYDVKGRFVIHRISAEEAKYKLCKVKKTQLGAKGVPFLVTHDGRTIRYPDPLIHANDSVQVDIASGKITDYIKFDSGNLCMITGGRNLGRVGTVVNRERHPGSFDIVHIKDSQGHVFATRLTNVFIIGKGNKPYISLPKGKGVKLSIAEERDKRLAAKTH", "length": 261 }, "evidence": [ { "id": "P79103", "url": "https://omabrowser.org/oma/group/P79103/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P47836-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "RPS4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIEKTGEHFRLVYDTKGRFAVHRITAEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P79103", "url": "https://omabrowser.org/oma/group/P79103/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P47961-1", "protein_name": "Small ribosomal subunit protein eS4", "gene_name": "RPS4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITSEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P79103", "url": "https://omabrowser.org/oma/group/P79103/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P62701-1", "protein_name": "Small ribosomal subunit protein eS4, X isoform", "gene_name": "RPS4X", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQSSG", "length": 263 }, "evidence": [ { "id": "P79103", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P79103", "url": "https://www.uniprot.org/uniprotkb/P79103" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P79103", "url": "https://www.uniprot.org/uniprotkb/P79103" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-P79103-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" }, "gene_names": [ { "name": "SPLUNC2A", "type": "recommended", "evidence": [ { "id": "P79124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79124" } ] }, { "name": "BPIFA2A", "type": "synonym", "evidence": [ { "id": "NP_777228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ] }, { "name": "BSP30A", "type": "synonym", "evidence": [ { "id": "NP_777228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" }, { "id": "P79124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79124" } ] }, { "name": "SPLUNC2A", "type": "synonym", "evidence": [ { "id": "NP_777228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ] } ], "protein_names": [ { "name": "Short palate, lung and nasal epithelium carcinoma-associated protein 2A", "type": "recommended", "evidence": [ { "id": "P79124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79124/entry#names_and_taxonomy" } ] }, { "name": "BSP30a", "type": "synonym", "evidence": [ { "id": "P79124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79124/entry#names_and_taxonomy" } ] }, { "name": "Common salivary protein form a", "type": "synonym", "evidence": [ { "id": "P79124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79124/entry#names_and_taxonomy" } ] }, { "name": "common salivary protein BSP30, form a", "type": "synonym", "evidence": [ { "id": "NP_777228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ] }, { "name": "common salivary protein form a", "type": "synonym", "evidence": [ { "id": "NP_777228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ] }, { "name": "short palate, lung and nasal epithelium carcinoma-associated protein 2A precursor", "type": "synonym", "evidence": [ { "id": "NP_777228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ] }, { "name": "short palate, lung and nasal epithelium carcinoma-associated protein 2A", "type": "synonym", "evidence": [ { "id": "NP_777228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ] } ], "function": [ { "annotation": "BSP30a and b contribute to the growth suppression function of bovine saliva through a mechanism independent of lipopolysaccharide opsonisation.", "evidence": [ { "database": "RefSeq", "id": "NP_777228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" }, { "database": "PubMed", "id": "18055015", "url": "https://glygen.org/publication/PubMed/18055015" } ] }, { "annotation": "Cloning and sequencing of two cDNAs, each containing a single open reading frame encoding a different form of BSP30", "evidence": [ { "database": "RefSeq", "id": "NP_777228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" }, { "database": "PubMed", "id": "12427544", "url": "https://glygen.org/publication/PubMed/12427544" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P79124", "url": "https://www.uniprot.org/uniprotkb/P79124" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPLUNC2A", "url": "https://www.uniprot.org/uniprotkb/P79124", "locus": {} } ], "crossref": [ { "id": "P79124", "url": "https://alphafold.ebi.ac.uk/entry/P79124", "database": "AlphaFoldDB", "categories": [] }, { "id": "286882", "url": "https://www.ncbi.nlm.nih.gov/gene/286882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:286882", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:286882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "P79124", "url": "https://www.orthodb.org/?gene=P79124", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47145:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47145:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_777228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "P79124", "url": "https://www.uniprot.org/uniprotkb/P79124", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P79124-1", "url": "https://www.uniprot.org/uniprotkb/P79124-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQLWKLVLLCGLLAGTSESLLDIRGNDVLRRLISGLERGLGTFDSTIEIIFQNLKTELESRCLNDVVEETQQTENSLEGLISRIFQVVNRLTGVRIRNVQVPDITFEATSENSADVSIPITADVTVSLPLLGEIVKLDLNVDLQTSVSIETDAETGDSRVVVGECPNNPESISLTVLHRRPGLLNDVVDFGVNLVRQLVSSVVQHELCPRIRELLESLDTECIKKLIGEPQVTTQQEI", "length": 239, "header": "sp|P79124-1|SPL2A_BOVIN Isoform 1 of Short palate, lung and nasal epithelium carcinoma-associated protein 2A OS=Bos taurus OX=9913 GN=SPLUNC2A PE=2 SV=2 CANONICAL=P79124-1" }, "isoforms": [ { "isoform_ac": "P79124-1", "url": "https://www.uniprot.org/uniprotkb/P79124/entry#P79124-1", "sequence": { "sequence": "MVQLWKLVLLCGLLAGTSESLLDIRGNDVLRRLISGLERGLGTFDSTIEIIFQNLKTELESRCLNDVVEETQQTENSLEGLISRIFQVVNRLTGVRIRNVQVPDITFEATSENSADVSIPITADVTVSLPLLGEIVKLDLNVDLQTSVSIETDAETGDSRVVVGECPNNPESISLTVLHRRPGLLNDVVDFGVNLVRQLVSSVVQHELCPRIRELLESLDTECIKKLIGEPQVTTQQEI", "length": 239, "header": "sp|P79124-1|SPL2A_BOVIN Isoform 1 of Short palate, lung and nasal epithelium carcinoma-associated protein 2A OS=Bos taurus OX=9913 GN=SPLUNC2A PE=2 SV=2 CANONICAL=P79124-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The BSP30 salivary proteins from cattle, LUNX/PLUNC and von Ebner's minor salivary gland protein are members of the PSP/LBP superfamily of proteins.", "journal": "Biochim. Biophys. Acta", "date": "2002", "authors": "Wheeler Thomas T, Haigh Brendan J, McCracken Judith Y, Wilkins Richard J, Morris Chris A, Grigor Murray R", "evidence": [ { "database": "UniProtKB", "id": "P79124", "url": "https://www.uniprot.org/uniprotkb/P79124" }, { "database": "RefSeq", "id": "NP_777228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ], "reference": [ { "type": "PubMed", "id": "12427544", "url": "https://glygen.org/publication/PubMed/12427544" } ] }, { "title": "The bovine salivary proteins BSP30a and BSP30b are independently expressed BPI-like proteins with anti-Pseudomonas activity.", "journal": "Molecular immunology", "date": "2008-04", "authors": "Haigh B, Hood K, Broadhurst M, Medele S, Callaghan M, Smolenski G, Dines M, Wheeler T", "evidence": [ { "database": "RefSeq", "id": "NP_777228", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777228" } ], "reference": [ { "type": "PubMed", "id": "18055015", "url": "https://glygen.org/publication/PubMed/18055015" } ] } ], "pathway": [ { "id": "bta:286882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:286882", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P79124", "url": "https://www.uniprot.org/uniprotkb/P79124" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "P79124", "url": "https://www.uniprot.org/uniprotkb/P79124" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "P79124", "url": 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{ "title": "The three dimensional structure of Bovine Salivary Protein 30b (BSP30b) and its interaction with specific rumen bacteria.", "journal": "PloS one", "date": "2019", "authors": "Zhang Heng, Burrows Judith, Card Graeme L, Attwood Graeme, Wheeler Tom T, Arcus Vickery L", "evidence": [ { "database": "RefSeq", "id": "NP_777227", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777227" } ], "reference": [ { "type": "PubMed", "id": "30978191", "url": "https://glygen.org/publication/PubMed/30978191" } ] } ], "pathway": [ { "id": "bta:286881", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:286881", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P79125", "url": "https://www.uniprot.org/uniprotkb/P79125" } ], "pmid": "" 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"PF13885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001073820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q05B44", "url": "https://www.uniprot.org/uniprotkb/Q05B44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B44-1", "url": "https://www.uniprot.org/uniprotkb/Q05B44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCHTSCSSGCQAACVPSSCQPSCSTSSPCHTSCFTSSLCQPTCSTSSTCQATCVPVSYRPAVCLPVTYKPTLCVTPSCQSSVFLPVSYRPAVYVAPSCQSSGCYQPSCPTLVYRPISCSTSSCF", "length": 124, "header": "sp|Q05B44-1|KR122_BOVIN Isoform 1 of Keratin-associated protein 12-2 OS=Bos taurus OX=9913 GN=KRTAP12-2 PE=2 SV=1 CANONICAL=Q05B44-1" }, "isoforms": [ { "isoform_ac": "Q05B44-1", "url": "https://www.uniprot.org/uniprotkb/Q05B44/entry#Q05B44-1", "sequence": { "sequence": "MCHTSCSSGCQAACVPSSCQPSCSTSSPCHTSCFTSSLCQPTCSTSSTCQATCVPVSYRPAVCLPVTYKPTLCVTPSCQSSVFLPVSYRPAVYVAPSCQSSGCYQPSCPTLVYRPISCSTSSCF", "length": 124, "header": "sp|Q05B44-1|KR122_BOVIN Isoform 1 of Keratin-associated protein 12-2 OS=Bos taurus OX=9913 GN=KRTAP12-2 PE=2 SV=1 CANONICAL=Q05B44-1" }, "locus": { "chromosome": "1", "start_pos": 144580103, "end_pos": 144579732, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024766.5", "url": "https://www.ensembl.org/id/ENSBTAT00000024766.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024766.4", "url": "https://www.ensembl.org/id/ENSBTAP00000024766.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783717", "resource": "KEGG Pathway" }, { "id": "R-BTA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805567", "resource": "Reactome", "description": "Keratinization" } ], "orthologs": [ { "uniprot_canonical_ac": "J3KMP7-1", "protein_name": "Keratin associated protein 12-21", "gene_name": "Krtap12-21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCHTSCSSGCQPSCCVSSPCQPSCCMSSSCQPSCCVSSSCQSACCRPAICIPVRYQVACCVPVSCRPTVCVAPSCQSSVCMPVSCRPVCVTSSCQSSGCCQPSCPTLVCRPVTCSNPSCC", "length": 120 }, "evidence": [ { "id": "Q05B44", "url": "https://omabrowser.org/oma/group/Q05B44/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59990-1", "protein_name": "Keratin-associated protein 12-1", "gene_name": "KRTAP12-1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCHTSCSSGCQPACCAPSPCQASCYIPVGCQSSVCVPVSFKPAVCVPVRCQSSVCVPVSCRPVVYAAPSCQSSGCCQPSCTSVLCRPISCSTPSCC", "length": 96 }, "evidence": [ { "id": "Q05B44", "url": "https://omabrowser.org/oma/group/Q05B44/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q05B44", "url": "https://www.uniprot.org/uniprotkb/Q05B44" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "Q05B44", "url": "https://www.uniprot.org/uniprotkb/Q05B44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q05B44-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 124, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q05B44-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q05B44" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q05B52-1", "uniprot_ac": "Q05B52", "uniprot_id": "COQ4_BOVIN", "mass": { "chemical_mass": 29626.0, "monoisotopic_mass": 29626.0 }, "refseq": { "ac": "NP_001077141", "name": "ubiquinone biosynthesis protein COQ4 homolog, mitochondrial isoform 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141" }, "gene_names": [ { "name": "COQ4", "type": "recommended", "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ] }, { "name": "COQ4", "type": "synonym", "evidence": [ { "id": "NP_001077141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141" } ] } ], "protein_names": [ { "name": "Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "type": "recommended", "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52/entry#names_and_taxonomy" } ] }, { "name": "4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase", "type": "synonym", "evidence": [ { "id": "NP_001077141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141" }, { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52/entry#names_and_taxonomy" } ] }, { "name": "4.1.1.130", "type": "synonym", "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52/entry#names_and_taxonomy" } ] }, { "name": "Coenzyme Q biosynthesis protein 4 homolog", "type": "synonym", "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52/entry#names_and_taxonomy" } ] }, { "name": "coenzyme Q biosynthesis protein 4 homolog", "type": "synonym", "evidence": [ { "id": "NP_001077141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141" } ] }, { "name": "coenzyme Q4 homolog", "type": "synonym", "evidence": [ { "id": "NP_001077141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141" } ] }, { "name": "ubiquinone biosynthesis protein COQ4 homolog, mitochondrial isoform 3", "type": "synonym", "evidence": [ { "id": "NP_001077141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141" } ] }, { "name": "ubiquinone biosynthesis protein COQ4 homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001077141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141" } ] } ], "function": [ { "annotation": "Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoic acid into 2-methoxy-6-(all-trans-decaprenyl)phenol during ubiquinone biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52#function" }, { "database": "HAMAP", "id": "MF_03111", "url": "https://hamap.expasy.org/signature/MF_03111" }, { "database": "UniProtKB", "id": "F1MJK0", "url": "https://www.uniprot.org/uniprotkb/F1MJK0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "COQ4", "url": "https://www.uniprot.org/uniprotkb/Q05B52", "locus": { "chromosome": "11", "start_pos": 98933765, "end_pos": 98919110, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004664", "url": "https://www.ensembl.org/id/ENSBTAG00000004664" } ] } } ], "crossref": [ { "id": "Q05B52", "url": "https://alphafold.ebi.ac.uk/entry/Q05B52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004664", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004664", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "511987", "url": "https://www.ncbi.nlm.nih.gov/gene/511987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511987", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TVYWEER", "url": "https://omabrowser.org/oma/group/TVYWEER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1G1", "url": "https://www.orthodb.org/?gene=A0A3Q1M1G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MJK0", "url": "https://www.orthodb.org/?gene=F1MJK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q05B52", "url": "https://www.orthodb.org/?gene=Q05B52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12922", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12922", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12922:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12922:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001077141", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077141", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "81275", "url": "https://www.rhea-db.org/rhea/81275", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M1G1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MJK0", "url": "https://www.uniprot.org/uniprotkb/F1MJK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MJK0-1", "url": "https://www.uniprot.org/uniprotkb/F1MJK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B52-1", "url": "https://www.uniprot.org/uniprotkb/Q05B52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B52-2", "url": "https://www.uniprot.org/uniprotkb/Q05B52-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLLRGVLRPLYAFRGGPGPPAGVPFRAVSHGTGLLYPEHIPTSVLQKVLLAAGSAGMALYDPYRHDMVAVLGETTGRRTLKVLRDQMKRDPEGAQILQERPRISLSTLDMGKLRSLPEGSFGRAYLHFLDVNRVSPDTRAPTRFVDDEELAYVIQRYREIHDMLHALLGMPTNILGEIVVKWFEAVQTGLPMCVLSALFGPIRLSAQSLQLLISELIPWAVENGRRAPCVLNVYYERRWEQPLQALRQELGITEPPLRVEGLV", "length": 265, "header": "sp|Q05B52-1|COQ4_BOVIN Isoform 1 of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Bos taurus OX=9913 GN=COQ4 PE=2 SV=2 CANONICAL=Q05B52-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1G1/entry", "sequence": { "sequence": "MATLLRGVLRPLYAFRGGPGPPAGVPFRAVSHGTGLLYPEHIPTSVLQKVLLAAGSAGMALYDPYRHDMVAVLGETTGRRTLKVLRDQMKRDPEGAQILQERPRISLSTLDMGKLRSLPEGSFGRAYLHFLDVNVRVPAETPCTSD", "length": 146, "header": "tr|A0A3Q1M1G1-1|COQ4_BOVIN Computationally mapped isoform of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Bos taurus OX=9913 GN=COQ4 PE=2 SV=1 CANONICAL=Q05B52-1" }, "locus": { "chromosome": "11", "start_pos": 98922472, "end_pos": 98919147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066477.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066477.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063553.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063553.1" } ] } }, { "isoform_ac": "F1MJK0-1", "url": "https://www.uniprot.org/uniprotkb/F1MJK0/entry", "sequence": { "sequence": "MATLLRGVLRPLYAFRGGPGPPAGVPFRAVSHGTGLLYPEHIPTSVLQKVLLAAGSAGMALYDPYRHDMVAVLGETTGRRTLKVLRDQMKRDPEGAQILQERPRISLSTLDMGKLRSLPEGSFGRAYLHFLDVNVASGRGMTRVSPDTRAPTRFVDDEELAYVIQRYREIHDMLHALLGMPTNILGEIVVKWFEAVQTGLPMCVLSALFGPIRLSAQSLQLLISELIPWAVENGRRAPCVLNVYYERRWEQPLQALRQELGITEPPLRVEGLV", "length": 273, "header": "tr|F1MJK0-1|F1MJK0_BOVIN Computationally mapped isoform of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Bos taurus OX=9913 GN=COQ4 PE=3 SV=2 CANONICAL=Q05B52-1" }, "locus": { "chromosome": "11", "start_pos": 98932761, "end_pos": 98919147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006120.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006120.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006120.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006120.5" } ] } }, { "isoform_ac": "Q05B52-1", "url": "https://www.uniprot.org/uniprotkb/Q05B52/entry#Q05B52-1", "sequence": { "sequence": "MATLLRGVLRPLYAFRGGPGPPAGVPFRAVSHGTGLLYPEHIPTSVLQKVLLAAGSAGMALYDPYRHDMVAVLGETTGRRTLKVLRDQMKRDPEGAQILQERPRISLSTLDMGKLRSLPEGSFGRAYLHFLDVNRVSPDTRAPTRFVDDEELAYVIQRYREIHDMLHALLGMPTNILGEIVVKWFEAVQTGLPMCVLSALFGPIRLSAQSLQLLISELIPWAVENGRRAPCVLNVYYERRWEQPLQALRQELGITEPPLRVEGLV", "length": 265, "header": "sp|Q05B52-1|COQ4_BOVIN Isoform 1 of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Bos taurus OX=9913 GN=COQ4 PE=2 SV=2 CANONICAL=Q05B52-1" }, "locus": { "chromosome": "11", "start_pos": 98932761, "end_pos": 98919147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061485.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061485.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053835.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053835.3" } ] } }, { "isoform_ac": "Q05B52-2", "url": "https://www.uniprot.org/uniprotkb/Q05B52/entry#Q05B52-2", "sequence": { "sequence": "MATLLRGVLRPLYAFRGGPGPPAGVPFRAVSHGTGLLYPEHIPTSVLQKVLLAAGSAGMALYDPYRHDMVAVLGETTGRRTLKVLRDQMKRDPEGAQILQERPRISLSTLDMGKLRSLPEGSFGRAYLHFLDVNVASGRGMTVCTEDFIQC", "length": 151, "header": "sp|Q05B52-2|COQ4_BOVIN Isoform 2 of Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial OS=Bos taurus OX=9913 GN=COQ4 PE=2 SV=2 CANONICAL=Q05B52-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 108, "end_pos": 108, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "site_lbl": "Ser108" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] } ], "pathway": [ { "id": "bta:511987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511987", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "pmid": "" }, { "name": "4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity", "id": "GO:0120539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120539", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q05B52", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "81275", "name": "", "equation": "4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoate + H(+) = 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q05B52-1" ], "evidence": [ { "id": "81275", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/81275" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q05B52", "gene_name": "COQ4", "activity": [ { "ec_number": "4.1.1.130", "activity": "4-hydroxy-3-methoxy-5-(all-trans-hexaprenyl)benzoate + H(+) = 2-methoxy-6-(all-trans-hexaprenyl)phenol + CO2.", "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q05B52-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 265, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q05B52-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q05B52" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52" }, { "id": "MF_03111", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03111" } ], "binding_site_uniprot": 163, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 163, "end_pos": 163, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52" }, { "id": "MF_03111", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03111" } ], "binding_site_uniprot": 164, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", "start_pos": 164, "end_pos": 164, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q05B52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B52" }, { "id": "MF_03111", "database": "HAMAP", "url": "https://hamap.expasy.org/signature/MF_03111" } ], "binding_site_uniprot": 167, "amino_acid": "His", "chebi_lig_id": "CHEBI:29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000255", 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"uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 187, "end_pos": 187, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.1.130", "ec_name": "4-hydroxy-3-methoxy-5-(all-trans-hexaprenyl)benzoate + H(+) = 2-methoxy-6-(all-trans-hexaprenyl)phenol + CO2.", "evidence": [ { "id": "4.1.1.130", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.130" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 108 ], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "uniprot_canonical_ac": "Q05B66-1", "uniprot_ac": "Q05B66", "uniprot_id": "OPA3_BOVIN", "mass": { "chemical_mass": 21261.0, "monoisotopic_mass": 21261.0 }, "refseq": { "ac": "NP_001073073", "name": "optic atrophy 3 protein homolog isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" }, "gene_names": [ { "name": "OPA3", "type": "recommended", "evidence": [ { "id": "Q05B66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B66" } ] }, { "name": "OPA3", "type": "synonym", "evidence": [ { "id": "NP_001073073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ] } ], "protein_names": [ { "name": "Optic atrophy 3 protein homolog", "type": "recommended", "evidence": [ { "id": "Q05B66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B66/entry#names_and_taxonomy" } ] }, { "name": "OPA3 outer mitochondrial membrane lipid metabolism regulator", "type": "synonym", "evidence": [ { "id": "NP_001073073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ] }, { "name": "mitochondrial optic atrophy 3 protein", "type": "synonym", "evidence": [ { "id": "NP_001073073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ] }, { "name": "optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)", "type": "synonym", "evidence": [ { "id": "NP_001073073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ] }, { "name": "optic atrophy 3 protein homolog isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001073073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ] }, { "name": "optic atrophy 3 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001073073", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ] } ], "function": [ { "annotation": "May play some role in mitochondrial processes.", "evidence": [ { "database": "UniProtKB", "id": "Q05B66", "url": "https://www.uniprot.org/uniprotkb/Q05B66#function" } ] }, { "annotation": "The nonsense mutation c.343C>T in the bovine OPA3 gene causes the late-onset dilated cardiomyopathy in Red Holstein cattle.", "evidence": [ { "database": "RefSeq", "id": "NP_001073073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" }, { "database": "PubMed", "id": "20923700", "url": "https://glygen.org/publication/PubMed/20923700" } ] }, { "annotation": "The present study is the first report of the OPA3 mutation in dilated cardiomyopathy affected cows outside Switzerland.", "evidence": [ { "database": "RefSeq", "id": "NP_001073073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" }, { "database": "PubMed", "id": "25947227", "url": "https://glygen.org/publication/PubMed/25947227" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q05B66", "url": "https://www.uniprot.org/uniprotkb/Q05B66" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OPA3", "url": "https://www.uniprot.org/uniprotkb/Q05B66", "locus": { "chromosome": "18", "start_pos": 53118230, "end_pos": 53185394, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019605", "url": "https://www.ensembl.org/id/ENSBTAG00000019605" } ] } } ], "crossref": [ { "id": "Q05B66", "url": "https://alphafold.ebi.ac.uk/entry/Q05B66", "database": "AlphaFoldDB", "categories": [] }, { "id": "523579", "url": "https://www.ncbi.nlm.nih.gov/gene/523579", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523579", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523579", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q05B66", "url": "https://www.orthodb.org/?gene=Q05B66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12499:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12499:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001073073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q05B66", "url": "https://www.uniprot.org/uniprotkb/Q05B66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B66-1", "url": "https://www.uniprot.org/uniprotkb/Q05B66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRAKMRLMGFNAETIKPLNEEAAAELGAELLGEATIFLVACGCLVLEYSRQKTQQRRKEGEQLAAWDAMRDEVDHLALVLEALQAQVQAAPPPGALEELQAQMREVRAQLCVQDLPPAPQEEPTPRDEGPPDPGLGQD", "length": 191, "header": "sp|Q05B66-1|OPA3_BOVIN Isoform 1 of Optic atrophy 3 protein homolog OS=Bos taurus OX=9913 GN=OPA3 PE=2 SV=1 CANONICAL=Q05B66-1" }, "isoforms": [ { "isoform_ac": "Q05B66-1", "url": "https://www.uniprot.org/uniprotkb/Q05B66/entry#Q05B66-1", "sequence": { "sequence": "MVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRAKMRLMGFNAETIKPLNEEAAAELGAELLGEATIFLVACGCLVLEYSRQKTQQRRKEGEQLAAWDAMRDEVDHLALVLEALQAQVQAAPPPGALEELQAQMREVRAQLCVQDLPPAPQEEPTPRDEGPPDPGLGQD", "length": 191, "header": "sp|Q05B66-1|OPA3_BOVIN Isoform 1 of Optic atrophy 3 protein homolog OS=Bos taurus OX=9913 GN=OPA3 PE=2 SV=1 CANONICAL=Q05B66-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A nonsense mutation in the optic atrophy 3 gene (OPA3) causes dilated cardiomyopathy in Red Holstein cattle.", "journal": "Genomics", "date": "2011-01", "authors": "Owczarek-Lipska Marta, Plattet Philippe, Zipperle Ljerka, Dr\u00f6gem\u00fcller Cord, Posthaus Horst, Dolf Gaudenz, Braunschweig Martin H", "evidence": [ { "database": "RefSeq", "id": "NP_001073073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ], "reference": [ { "type": "PubMed", "id": "20923700", "url": "https://glygen.org/publication/PubMed/20923700" } ] }, { "title": "Detection of the nonsense mutation of OPA3 gene in Holstein Friesian cattle with dilated cardiomyopathy in Japan.", "journal": "The Journal of veterinary medical science", "date": "2015-10", "authors": "Horiuchi Noriyuki, Kumagai Daishiro, Matsumoto Kotaro, Inokuma Hisashi, Furuoka Hidefumi, Kobayashi Yoshiyasu", "evidence": [ { "database": "RefSeq", "id": "NP_001073073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073073" } ], "reference": [ { "type": "PubMed", "id": "25947227", "url": "https://glygen.org/publication/PubMed/25947227" } ] } ], "pathway": [ { "id": "bta:523579", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523579", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q05B66", "url": "https://www.uniprot.org/uniprotkb/Q05B66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of lipid metabolic process", "id": "GO:0019216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019216", "evidence": [ { "database": "UniProtKB", "id": "Q05B66", "url": "https://www.uniprot.org/uniprotkb/Q05B66" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "Q05B66", "url": "https://www.uniprot.org/uniprotkb/Q05B66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q05B66-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 191, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q05B66-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q05B66" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q05B67-1", "uniprot_ac": "Q05B67", "uniprot_id": "MIMS1_BOVIN", "mass": { "chemical_mass": 31025.0, "monoisotopic_mass": 31025.0 }, "refseq": { "ac": "NP_001422134", "name": "protein FAM210A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422134" }, "gene_names": [ { "name": "MIMS1", "type": "recommended", "evidence": [ { "id": "Q05B67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B67" } ] }, { "name": "C18orf19", "type": "synonym", "evidence": [ { "id": "NP_001422134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422134" } ] }, { "name": "C24H18orf19", "type": "synonym", "evidence": [ { "id": "NP_001422134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422134" } ] }, { "name": "FAM210A", "type": "synonym", "evidence": [ { "id": "NP_001422134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422134" }, { "id": "Q05B67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B67" } ] } ], "protein_names": [ { "name": "Mitochondrial inner membrane scaffold 1", "type": "recommended", "evidence": [ { "id": "Q05B67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B67/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM210A", "type": "synonym", "evidence": [ { "id": "Q05B67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B67/entry#names_and_taxonomy" } ] }, { "name": "protein FAM210A", "type": "synonym", "evidence": [ { "id": "NP_001422134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422134" } ] }, { "name": "uncharacterized protein C18orf19 homolog", "type": "synonym", "evidence": [ { "id": "NP_001422134", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422134" } ] } ], "function": [ { "annotation": "Mitochondrial inner membrane protein essential for mitochondrial homeostasis, structural integrity, and cellular metabolism. Regulates mitochondrial translation by modulating protein synthesis of mitochondrial DNA-encoded genes. Plays a critical role in skeletal muscle mass and strength by regulating mitochondrial density, function, and protein synthesis. In brown adipose tissue, regulates mitochondrial cristae remodeling in response to cold stress by interacting with mitochondrial protease YME1L1 and enhancing its proteolytic activity, promoting OMA1 degradation and regulating OPA1 processing. Required for cardiac mitochondrial homeostasis and normal cardiomyocyte contractile function. In skeletal muscle, positively regulates myoblast differentiation by enhancing expression of myogenic factors.", "evidence": [ { "database": "UniProtKB", "id": "Q05B67", "url": "https://www.uniprot.org/uniprotkb/Q05B67#function" }, { "database": "UniProtKB", "id": "Q8BGY7", "url": "https://www.uniprot.org/uniprotkb/Q8BGY7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q05B67", "url": "https://www.uniprot.org/uniprotkb/Q05B67" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MIMS1", "url": "https://www.uniprot.org/uniprotkb/Q05B67", "locus": {} } ], "crossref": [ { "id": "Q05B67", "url": "https://alphafold.ebi.ac.uk/entry/Q05B67", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009141", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009141", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "511554", "url": "https://www.ncbi.nlm.nih.gov/gene/511554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511554", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511554", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MQWNVLR", "url": "https://omabrowser.org/oma/group/MQWNVLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q05B67", "url": "https://www.orthodb.org/?gene=Q05B67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21377:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21377:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422134", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422134", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q05B67", "url": "https://www.uniprot.org/uniprotkb/Q05B67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q05B67-1", "url": "https://www.uniprot.org/uniprotkb/Q05B67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQWNVPKTVFRLAHRTCMEPHKAGLLGHCQNMKGPLLLYTLESRVVVVQGPQKRWLHLPTAQCVAKERKPFTAVQSQPGVFHHKQWEQDILSKRVLSSSATSSGPPSEKKEDPDPLQDRSISLYQRFKKTFRQYGKVLIPVHLITSAVWFGTFYYAAMKGVNVVPFLELIGLPDSIVNILKNSQSGNALTAYALFKIATPARYTVTLGGTSFTVKYLRSRGYMSTPPPVKEYLQDKMEETKELLTEKMEETKDRLTEKLQETKGKVSLKKKVE", "length": 273, "header": "sp|Q05B67-1|MIMS1_BOVIN Isoform 1 of Mitochondrial inner membrane scaffold 1 OS=Bos taurus OX=9913 GN=MIMS1 PE=2 SV=1 CANONICAL=Q05B67-1" }, "isoforms": [ { "isoform_ac": "Q05B67-1", "url": "https://www.uniprot.org/uniprotkb/Q05B67/entry#Q05B67-1", "sequence": { "sequence": "MQWNVPKTVFRLAHRTCMEPHKAGLLGHCQNMKGPLLLYTLESRVVVVQGPQKRWLHLPTAQCVAKERKPFTAVQSQPGVFHHKQWEQDILSKRVLSSSATSSGPPSEKKEDPDPLQDRSISLYQRFKKTFRQYGKVLIPVHLITSAVWFGTFYYAAMKGVNVVPFLELIGLPDSIVNILKNSQSGNALTAYALFKIATPARYTVTLGGTSFTVKYLRSRGYMSTPPPVKEYLQDKMEETKELLTEKMEETKDRLTEKLQETKGKVSLKKKVE", "length": 273, "header": "sp|Q05B67-1|MIMS1_BOVIN Isoform 1 of Mitochondrial inner membrane scaffold 1 OS=Bos taurus OX=9913 GN=MIMS1 PE=2 SV=1 CANONICAL=Q05B67-1" }, "locus": { "chromosome": "24", "start_pos": 43494420, "end_pos": 43487672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012046.4", "url": "https://www.ensembl.org/id/ENSBTAT00000012046.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012046.3", "url": "https://www.ensembl.org/id/ENSBTAP00000012046.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511554", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511554", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061ICD1-1", "protein_name": "Protein FAM210A", "gene_name": "Fam210a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/Q05B67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGY7-1", "protein_name": "Mitochondrial inner membrane scaffold 1", "gene_name": "Mims1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQWNVPRTMSRLALRTFVEAQKARLFDHHWRIKGPLLVHRGEYRVAWTPHLRKQWLHLSAVQCLAKQRNLLDAQPPQLGTLRQERWEQDILSKRVLSSSSTSQETPSEKKEETDPLQDKSISLYQRFKKTFRQYGKVLIPVHLITSGIWFGTFYYATIKGVNVIPFLEVIGLPDSIVDILKNSQSGNALTAYAMFKIATPARYTVTLGGTSFTVKYLRSHGYMSTPPPVKEYLQGRMEETKELITEKMEETKDRLTEKLQETKGKVSFKKKVE", "length": 273 }, "evidence": [ { "id": "Q05B67", "url": "https://omabrowser.org/oma/group/Q05B67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96ND0-1", "protein_name": "Mitochondrial inner membrane scaffold 1", "gene_name": "MIMS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQWNVPRTVSRLARRTCLEPHNAGLFGHCQNVKGPLLLYNAESKVVLVQGPQKQWLHLSAAQCVAKERRPLDAHPPQPGVLRHKQGKQHVSFRRVFSSSATAQGTPEKKEEPDPLQDKSISLYQRFKKTFRQYGKVLIPVHLITSGVWFGTFYYAALKGVNVVPFLELIGLPDSVVSILKNSQSGNALTAYALFKIATPARYTVTLGGTSVTVKYLRSHGYMSTPPPVKEYLQDRMEETKELITEKMEETKDRLTEKLQETKEKVSFKKKVE", "length": 272 }, "evidence": [ { "id": "Q05B67", "url": "https://omabrowser.org/oma/group/Q05B67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q05B67", "url": "https://www.uniprot.org/uniprotkb/Q05B67" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q05B67", "url": "https://www.uniprot.org/uniprotkb/Q05B67" } ], "pmid": "" }, { 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DG7-1", "uniprot_ac": "Q08DG7", "uniprot_id": "HXA3_BOVIN", "mass": { "chemical_mass": 46280.0, "monoisotopic_mass": 46280.0 }, "refseq": { "ac": "NP_001070293", "name": "homeobox protein Hox-A3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070293" }, "gene_names": [ { "name": "HOXA3", "type": "recommended", "evidence": [ { "id": "Q08DG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DG7" } ] }, { "name": "HOXA3", "type": "synonym", "evidence": [ { "id": "NP_001070293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070293" } ] } ], "protein_names": [ { "name": "Homeobox protein Hox-A3", "type": "recommended", "evidence": [ { "id": "Q08DG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DG7/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-A3", "type": "synonym", "evidence": [ { "id": "NP_001070293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070293" } ] } ], "function": [ { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "Q08DG7", "url": "https://www.uniprot.org/uniprotkb/Q08DG7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DG7", "url": "https://www.uniprot.org/uniprotkb/Q08DG7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HOXA3", "url": "https://www.uniprot.org/uniprotkb/Q08DG7", "locus": { "chromosome": "4", "start_pos": 68934981, "end_pos": 68902556, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008139", "url": "https://www.ensembl.org/id/ENSBTAG00000008139" } ] } } ], "crossref": [ { "id": "Q08DG7", "url": "https://alphafold.ebi.ac.uk/entry/Q08DG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008139", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008139", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509991", "url": "https://www.ncbi.nlm.nih.gov/gene/509991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509991", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509991", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDYDPHP", "url": "https://omabrowser.org/oma/group/PDYDPHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q08DG7", "url": "https://www.orthodb.org/?gene=Q08DG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45664:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45664:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13293", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q08DG7", "url": "https://www.uniprot.org/uniprotkb/Q08DG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DG7-1", "url": "https://www.uniprot.org/uniprotkb/Q08DG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKATYYDSSAIYGGYPYQAANGFGYNANQQPYPASTALGADGEYHRPACSLQSPANAGSHPKAHELSEACLRTLSGPPSQPPVLGEPPLAPPPPQAAPPAPPQPPAPPQPPAPTPAAPPPPSSVSPPQNGSSNPTPASAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGPGSYLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHLQGSPVFVGGSYVEPMSNSGPPLFGLTHLPHTASAAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL", "length": 442, "header": "sp|Q08DG7-1|HXA3_BOVIN Isoform 1 of Homeobox protein Hox-A3 OS=Bos taurus OX=9913 GN=HOXA3 PE=2 SV=1 CANONICAL=Q08DG7-1" }, "isoforms": [ { "isoform_ac": "Q08DG7-1", "url": "https://www.uniprot.org/uniprotkb/Q08DG7/entry#Q08DG7-1", "sequence": { "sequence": "MQKATYYDSSAIYGGYPYQAANGFGYNANQQPYPASTALGADGEYHRPACSLQSPANAGSHPKAHELSEACLRTLSGPPSQPPVLGEPPLAPPPPQAAPPAPPQPPAPPQPPAPTPAAPPPPSSVSPPQNGSSNPTPASAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGPGSYLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHLQGSPVFVGGSYVEPMSNSGPPLFGLTHLPHTASAAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL", "length": 442, "header": "sp|Q08DG7-1|HXA3_BOVIN Isoform 1 of Homeobox protein Hox-A3 OS=Bos taurus OX=9913 GN=HOXA3 PE=2 SV=1 CANONICAL=Q08DG7-1" }, "locus": { "chromosome": "4", "start_pos": 68934073, "end_pos": 68931324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010700.5", "url": "https://www.ensembl.org/id/ENSBTAT00000010700.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010700.4", "url": "https://www.ensembl.org/id/ENSBTAP00000010700.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 338, "start_aa": "Thr", "end_pos": 338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr338", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:509991", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509991", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0D9SEG7-1", "protein_name": "Homeobox A3", "gene_name": "HOXA3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQKATYYDSSAIYGAYPYQGANGFTYNASQQQYPPSSSLVETEYHRPACSLQSPGSAVSHHKANDISESCMRTLPSQPLQPPGLTDPQAPPQPPPAPQAQPPPPSSASPSQNASSNPAPANSTKSPALNSPTVSKQIFPWMKESRQNTKQKNSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMMTSSGGQSPSRSPVPPAAGGYLNSMHSLVNSVPYEPQSPPPFNKPHQNTYGIPASYTAPLNNCPPPQKRYTGTAAVTPEYDTHPLQGNGYGNPHIQGSPVYVGGNYVETMTNSGPSIFGLTHLSHPPSANMDYSGAGPMGNNHHHGPCDPHPTYTDLTAHHPSQGRIQEAPKLTHL", "length": 413 }, "evidence": [ { "id": "Q08DG7", "url": "https://omabrowser.org/oma/group/Q08DG7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZM81-1", "protein_name": "Homeobox A3", "gene_name": "Hoxa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQKATYYDSSAIYGGYPYQAANGFAYNASQQPYAPSATLGTDGVEYHRPACSLQSPASAGAHPKSHELSEACLRTLSGPPSQPPGLGDPPLPPPPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSANSNPTPASTAKSPLLNSPTVGKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPPQKRYTAAGSGAGGTPEYDPHAHGLQGNGSYGTPHLQGSPVFVGGSYVEPMGNSGPALFGLTHLPHTTSAAVDYGGSGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL", "length": 444 }, "evidence": [ { "id": "Q08DG7", "url": "https://omabrowser.org/oma/group/Q08DG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SHT1-1", "protein_name": "Homeobox A3", "gene_name": "HOXA3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQKATYYDSSAIYGGYPYQAANGFGYNASQQPYPASAALGADGEYHRPACSLQSPANAGGHPKAHELSEACLRTLSGPPSQPPGLGEPPLAPPPPQAAPPAPQQPQPPQQPPAPAPAAPPPPSSVSPPQNASSNPTPASAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHLQGSPVFVGGSYVEPMSNSGPPLFGLTHLPHAASAAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL", "length": 443 }, "evidence": [ { "id": "Q08DG7", "url": "https://omabrowser.org/oma/group/Q08DG7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43365-1", "protein_name": "Homeobox protein Hox-A3", "gene_name": "HOXA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL", "length": 443 }, "evidence": [ { "id": "Q08DG7", "url": "https://omabrowser.org/oma/group/Q08DG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02831-1", "protein_name": "Homeobox protein Hox-A3", "gene_name": "Hoxa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQKATYYDSSAIYGGYPYQAANGFAYNASQQPYAPSAALGTDGVEYHRPACSLQSPASAGGHPKTHELSEACLRTLSGPPSQPPGLGEPPLPPPPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSANSNPTPASTAKSPLLNSPTVGKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPPQKRYTAAGSGAGGTPDYDPHAHGLQGNGSYGTPHLQGSPVFVGGSYVEPMSNSGPLFGLTHLPHTTSAAMDYGGTGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL", "length": 443 }, "evidence": [ { "id": "Q08DG7", "url": "https://omabrowser.org/oma/group/Q08DG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q08DG7", "url": "https://www.uniprot.org/uniprotkb/Q08DG7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": 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homolog", "type": "recommended", "evidence": [ { "id": "Q08DJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7/entry#names_and_taxonomy" } ] }, { "name": "AAR2 splicing factor homolog", "type": "synonym", "evidence": [ { "id": "Q08DJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7/entry#names_and_taxonomy" } ] }, { "name": "protein AAR2 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005214822", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214822" } ] } ], "function": [ { "annotation": "Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "Q08DJ7", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7#function" }, { "database": "UniProtKB", "id": "P32357", "url": "https://www.uniprot.org/uniprotkb/P32357#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DJ7", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AAR2", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7", "locus": { "chromosome": "13", "start_pos": 65380067, "end_pos": 65359908, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001645", "url": "https://www.ensembl.org/id/ENSBTAG00000001645" } ] } } ], "crossref": [ { "id": "Q08DJ7", "url": "https://alphafold.ebi.ac.uk/entry/Q08DJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001645", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001645", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13778", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13778", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "533351", "url": "https://www.ncbi.nlm.nih.gov/gene/533351", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VWQSGGL", "url": "https://omabrowser.org/oma/group/VWQSGGL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q08DJ7", "url": "https://www.orthodb.org/?gene=Q08DJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12689", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12689", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12689:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12689:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005214822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214822", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q08DJ7", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DJ7-1", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAMQMDPELARRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHYSSVDKANPREVGPRMGFFLNLQQRGLKVLRWDAAREEVDLSPAPEAEVEAMRANLQELDQFLGPYPYTTLKKWISLTNFISEATVEKLQPESRQICAFSEVLPVLSMRHTKDRVGQNLPRCGAECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPAGATPAEITRHSMDLSYALETVLSKQFPCSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEEAMVKHHSLYVNLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSARSVAVDATLRQKAERFQAHLTKKFRWDFEAEPEDCAPVVVELPDGVGTG", "length": 384, "header": "sp|Q08DJ7-1|AAR2_BOVIN Isoform 1 of Protein AAR2 homolog OS=Bos taurus OX=9913 GN=AAR2 PE=2 SV=1 CANONICAL=Q08DJ7-1" }, "isoforms": [ { "isoform_ac": "Q08DJ7-1", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7/entry#Q08DJ7-1", "sequence": { "sequence": "MAAMQMDPELARRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHYSSVDKANPREVGPRMGFFLNLQQRGLKVLRWDAAREEVDLSPAPEAEVEAMRANLQELDQFLGPYPYTTLKKWISLTNFISEATVEKLQPESRQICAFSEVLPVLSMRHTKDRVGQNLPRCGAECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPAGATPAEITRHSMDLSYALETVLSKQFPCSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEEAMVKHHSLYVNLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSARSVAVDATLRQKAERFQAHLTKKFRWDFEAEPEDCAPVVVELPDGVGTG", "length": 384, "header": "sp|Q08DJ7-1|AAR2_BOVIN Isoform 1 of Protein AAR2 homolog OS=Bos taurus OX=9913 GN=AAR2 PE=2 SV=1 CANONICAL=Q08DJ7-1" }, "locus": { "chromosome": "13", "start_pos": 65378916, "end_pos": 65362825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002156.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002156.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002156.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002156.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0P7-1", "protein_name": "Protein AAR2 homolog", "gene_name": "Aar2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVFNQVHKVTHQSLELKGFKETKKESCFWLPSTGLMASMQMDPELAKQLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGVHFLYYSSVDKANPREVGPRMGFFLSLKQRELTVLRWNAVQEEVDLSPAPEAEVEAMRANLPELDQFLGPYPYGTLKKWISLTNFISEATMEKLQPESRQICAFSDVLPVLSMRYTKDRVEQNLPLCGTECRSYQEGLARLPEMKPRAGTEIRFSELPTQMFPAGATPAEITRHSMDLSYALETVLSKQFPGNPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSETAMVKHHALYVSLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSVAVEATLRKKAEKFQAHLTKKFRWDFTSEPEDCAPVVVELPENIETA", "length": 420 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1P5Y2-1", "protein_name": "Protein AAR2 homolog", "gene_name": "AAR2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGPQADPELAKRLFFEGAAVVVLGVPEGTEFGIDYNSWTVGPRFRGVKMVPPGVHFVHCSAARTAGGTETGPRAGLFLCLRPRQVRALRWEPGSEELREAAPGEEEALGRDLREMDAFLGPYPYETLKKWISLSSFVGEAAVERLQPESGQISAFSEVLPVRAGRHGRDRAGQKLPPYDAGCGSYAEGVARLPEMRPRAGTEIRFTELPRQTYPDGASPEEITRHSMDLSYALEKVIARRYAGRPQDLLAELQFAFICFLIGNVYDAFEHWKRLLNILCRSEDAIAKYQDLYANLIFVLYHQLNEIPSDFFVDIVSQDNFLTSTLQVFFSYTCNAAVDGALRKKAEKFKAHLTKKFKWDFDAEPDDCAPVVVELPEGVLTD", "length": 382 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1R8D9-1", "protein_name": "Protein AAR2 homolog", "gene_name": "aar2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGTDMDPEVARGLFEEGATLVLLGVPEGTELGLDYKTWTLGPRFRGVKMIPPGLHFLHYCSVSTNGGCGEISPKTGLFLSLKPRQVLVAHWNKSADDLEISQNSEEVERVRGNLKELDRYLGPYPYDTLRKWVSLTDRLSQEVAVALQPLSGRVCAFSDVIPELQLTHTKDRVQQNLSRNDQECQSMKEGLDRLPRMKQREGTELRFSSIPKQAYPPGATPAQITQYSMDRSYILNAVLERHYKEQPLNVLGELQFAFVCFLVGNVYEAFEHWKSLLALLCRSEEAMKDRKELYLGLIAVLYHQLGEIPPDFFVDIVSQSNFLTSTLQDFFQFASSPGVDSTLRKRAEKFKVHLTKKFRWDFDADLDDCAPVVVELPDGVTVD", "length": 384 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S484-1", "protein_name": "Protein AAR2 homolog", "gene_name": "AAR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATMQMDPELAKRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHYSSVDKANPREMGPRMGFFLSLQQRGLMVLRWNAVREEVDLSPAPEAEVEAMRANLQELDQFLGPYPYATLKKWISLTSFISETTVEKLQPESRHICAFSEVLPVLSMKHTKDRVGQNLPRCGTECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPAGATPAEITRHSMDLSYALETVLSKHFPNSPQDVLGELQFAFVCFLLGNVYEAFEHWKQLLNLLCRSEEAMVKHHTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSVAVDATLRQKAEKFQAHLTKKFRWDFAAEPEDCAPVVVELPEGVGTG", "length": 384 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GXV6-1", "protein_name": "Protein AAR2 homolog", "gene_name": "Aar2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASMQMDPELAKQLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHYSSVDKANPREVGPRMGFFLSLKQRGLTVLRWNAVQEEVDLSPAPEAEVEAMRANLPELDQFLGPYPYATLKKWISLTSFINEATMEKLQPESRQICAFSDVLPVLSMKHTKDRVEQNLPLCGTECKSYQEGLARLPEMKPRAGTEIRFSELPAQMFPAGATPAEITRHSMDLSYALETVLSKQFPCNPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMVKHHTLYVSLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKFQAHLTKKFRWDFASEPEDCAPVVVELPEGIETG", "length": 384 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54R71-1", "protein_name": "Protein AAR2 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNEKARELNEKYATLLILDVPEGSTIGIDNKVWTSGPMFKGVKMIPPGVHMFHCTSSNEYGDSVLISSSFIWVNEINNNKKNNNNNNNKDNYVGEETNGSQQVFIKRWNKEEEDFFPDQSITEQEIQSYTYAVRNFEFDKNLAPYPFDGTQIQWNLLTSHITKSLLDRILPISNIINGDSCSYDQQQNSASSKKEKKLLNDLDLKLKQFNESRGSPSTSSTTTTTTTTTTTSSTTNNSKSKNWGVPYFSKIPKNPIIQNSTATTTTGNNSIDISNLSKWNIDKSECIEFIINKYYKDNEMDLLGEIEFCFVLFIFGMTWSGFQQWKELVTLFLSCDELVLKKPILFIEFFKILKNQLQEAPNDMFESELSNRVFIKPLLKQFIESVYNPEFTNLEQLSPIQLQLFKTIIDLKNYVSNKFNWNLNLFNQINFNNNYNENNNKPFGIKKEYNENNKNKDDDDDEDDDDDEEEDNNNNNNNSNEKSINYQQQNNYDNEDYDSEDDEYKPVLVMDTDMNYL", "length": 518 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9C711-1", "protein_name": "AAR2 protein family", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSEKALELVKHGATLLFLDVPQYTLVGIDTQIFAVGPAFKGIKMIPPGIHFVFYSSSTRDGREFSPTIGFFVDVAPSQVIVRKWNQQDEWLTKVSEEEEERYSQAVRSLEFDKNLGPYNLKQYGEWRHLSNYITKDVVEKFEPVGGEITVTYESAILKGGPKTAMEIALDTQMKKSKFTTSSTEQPKGNRFYYTSIPRIIKHKGMSGQELTSMNLDKTQLLESVLSKEYKDSEDLLLGELQFSFVAFLMGQSLESFMQWKSIVSLLLGCTSAPFQTRSQLFTKFIKVIYHQLKYGLQKENSGPETGIHALLDDSWLASDSFLHFLCKDFFALVEETSVVDGDLLSWTRKFKELLENRLGWEFQKKSAVDGIYFEEDDEYAPVVEMLDESHGEYMDKTT", "length": 399 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VEA6-1", "protein_name": "Protein AAR2 homolog", "gene_name": "Dmel\\CG12320", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKDNSSMKMDPQLALRLLADGGVLVIAGVPEGTEFGIDLCAYTIGPDFRGVKMIPPGVHYVWCSSRGPYGDAAPRVGFVHFFHPNEIVVREWDHELEELRPRRIAEPEVERDRIRKNLAQLERVLAPYDYRYVVQWKELTGSVTESCVDRCRPTEGTIRTNIELQSCPDADRPRGGAATVSISRRNAAARILLDESELLPDLKPVEGTAPRFTTVPLRVPQDALPADVSRHALDCIDAVDKLLEGFETADGLIEELQLAYAFFLVGYSVESLAHWRKLLGLLAHSQTAVTKHKLTYMKYSEVLAHQLPHLPEELMVPGPHNTVYKDVRELLVNLHAGGLSVSAERLTKRLEKKLGWEFEGLLDEDPEDQPVVIELPEA", "length": 379 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y312-1", "protein_name": "Protein AAR2 homolog", "gene_name": "AAR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVQMDPELAKRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHYSSVDKANPKEVGPRMGFFLSLHQRGLTVLRWSTLREEVDLSPAPESEVEAMRANLQELDQFLGPYPYATLKKWISLTNFISEATVEKLQPENRQICAFSDVLPVLSMKHTKDRVGQNLPRCGIECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVLNKQFPSSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKFQAHLTKKFRWDFAAEPEDCAPVVVELPEGIEMG", "length": 384 }, "evidence": [ { "id": "Q08DJ7", "url": "https://omabrowser.org/oma/group/Q08DJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "Q08DJ7", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q08DJ7", "url": "https://www.uniprot.org/uniprotkb/Q08DJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DJ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 384, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DJ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DJ7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 221 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DK5-1", "uniprot_ac": "Q08DK5", "uniprot_id": "SHLB2_BOVIN", "mass": { "chemical_mass": 44051.0, "monoisotopic_mass": 44051.0 }, "refseq": { "ac": "NP_001070270", "name": "endophilin-B2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070270" }, "gene_names": [ { "name": "SH3GLB2", "type": "recommended", "evidence": [ { "id": "Q08DK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DK5" } ] }, { "name": "SH3GLB2", "type": "synonym", "evidence": [ { "id": "NP_001070270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070270" } ] } ], "protein_names": [ { "name": "Endophilin-B2", "type": "recommended", "evidence": [ { "id": "Q08DK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DK5/entry#names_and_taxonomy" } ] }, { "name": "SH3 domain-containing GRB2-like protein B2", "type": "synonym", "evidence": [ { "id": "NP_001070270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070270" }, { "id": "Q08DK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DK5/entry#names_and_taxonomy" } ] }, { "name": "SH3-domain GRB2-like endophilin B2", "type": "synonym", "evidence": [ { "id": "NP_001070270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070270" } ] }, { "name": "endophilin-B2", "type": "synonym", "evidence": [ { "id": "NP_001070270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070270" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DK5", "url": "https://www.uniprot.org/uniprotkb/Q08DK5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SH3GLB2", "url": "https://www.uniprot.org/uniprotkb/Q08DK5", "locus": { "chromosome": "11", "start_pos": 99489806, "end_pos": 99506851, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010626", "url": "https://www.ensembl.org/id/ENSBTAG00000010626" } ] } } ], "crossref": [ { "id": "Q08DK5", "url": "https://alphafold.ebi.ac.uk/entry/Q08DK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010626", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010626", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11944", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11944", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "504750", "url": "https://www.ncbi.nlm.nih.gov/gene/504750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504750", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVS3", "url": "https://www.orthodb.org/?gene=A0A3Q1LVS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MMV0", "url": "https://www.orthodb.org/?gene=A0A3Q1MMV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A452DIH3", "url": "https://www.orthodb.org/?gene=A0A452DIH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q08DK5", "url": "https://www.orthodb.org/?gene=Q08DK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-264870", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-264870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001070270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVS3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCB6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKD0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMV0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIH3", "url": "https://www.uniprot.org/uniprotkb/A0A452DIH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DK5", "url": "https://www.uniprot.org/uniprotkb/Q08DK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DK5-1", "url": "https://www.uniprot.org/uniprotkb/Q08DK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGRFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 395, "header": "sp|Q08DK5-1|SHLB2_BOVIN Isoform 1 of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=2 SV=1 CANONICAL=Q08DK5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLL1/entry", "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATTVPDFQETRPRNYILSASASATLEDTCRPPSWAEWKEDYPGGWRRPCFFLVPLNPSLTLARGCLSLPKDRKLWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGRFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 445, "header": "tr|A0A3Q1LLL1-1|A0A3Q1LLL1_BOVIN Computationally mapped isoform of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=3 SV=1 CANONICAL=Q08DK5-1" }, "locus": { "chromosome": "11", "start_pos": 99506687, "end_pos": 99490476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070343.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070343.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057662.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057662.1" } ] } }, { "isoform_ac": "A0A3Q1LVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS3/entry", "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATCEGDTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 404, "header": "tr|A0A3Q1LVS3-1|A0A3Q1LVS3_BOVIN Computationally mapped isoform of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=3 SV=2 CANONICAL=Q08DK5-1" }, "locus": { "chromosome": "11", "start_pos": 99506687, "end_pos": 99490476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082745.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082745.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059438.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059438.2" } ] } }, { "isoform_ac": "A0A3Q1MCB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB6/entry", "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISVRSLELRTVPDFQETRPRNYILSASASAVSAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGRFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 365, "header": "tr|A0A3Q1MCB6-1|SHLB2_BOVIN Computationally mapped isoform of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=2 SV=2 CANONICAL=Q08DK5-1" }, "locus": { "chromosome": "11", "start_pos": 99506687, "end_pos": 99490476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076065.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076065.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066408.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066408.2" } ] } }, { "isoform_ac": "A0A3Q1MKD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKD0/entry", "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 371, "header": "tr|A0A3Q1MKD0-1|SHLB2_BOVIN Computationally mapped isoform of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=2 SV=1 CANONICAL=Q08DK5-1" }, "locus": { "chromosome": "11", "start_pos": 99506687, "end_pos": 99490476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067317.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067317.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071970.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071970.1" } ] } }, { "isoform_ac": "A0A3Q1MMV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMV0/entry", "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATLWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGSSQGAIFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 379, "header": "tr|A0A3Q1MMV0-1|SHLB2_BOVIN Computationally mapped isoform of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=2 SV=1 CANONICAL=Q08DK5-1" }, "locus": { "chromosome": "11", "start_pos": 99506687, "end_pos": 99490476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076951.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076951.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073163.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073163.1" } ] } }, { "isoform_ac": "A0A452DIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIH3/entry", "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATTVPDFQETRPRNYILSASASAAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGRFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 387, "header": "tr|A0A452DIH3-1|SHLB2_BOVIN Computationally mapped isoform of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=2 SV=2 CANONICAL=Q08DK5-1" }, "locus": { "chromosome": "11", "start_pos": 99506687, "end_pos": 99490476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014049.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014049.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014049.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014049.6" } ] } }, { "isoform_ac": "Q08DK5-1", "url": "https://www.uniprot.org/uniprotkb/Q08DK5/entry#Q08DK5-1", "sequence": { "sequence": "MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFESLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPTTPYGKTLIKVAEAEKHLGAAERDFIHTASINFLTPLRNFLEGDWKTISKERRLLQNRRLDLDASKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFIESQTTYYAQCYRHMLDLQKQLGRFPGTFVGTAEPASPPLSSTSPTTTAATMPMGPSVADLAPPGEAALRLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 395, "header": "sp|Q08DK5-1|SHLB2_BOVIN Isoform 1 of Endophilin-B2 OS=Bos taurus OX=9913 GN=SH3GLB2 PE=2 SV=1 CANONICAL=Q08DK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 10, "end_pos": 10, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DK5", "url": "https://www.uniprot.org/uniprotkb/Q08DK5" } ], "site_lbl": "Ser10" }, { "start_pos": 395, "end_pos": 395, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DK5", "url": "https://www.uniprot.org/uniprotkb/Q08DK5" } ], "site_lbl": "Ser395" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504750", "resource": "KEGG Pathway" }, { "id": "R-BTA-264870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-264870", "resource": "Reactome", "description": "Caspase-mediated cleavage of 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"evidence": [ { "database": "UniProtKB", "id": "Q08DM5", "url": "https://www.uniprot.org/uniprotkb/Q08DM5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q08DM5", "url": "https://www.uniprot.org/uniprotkb/Q08DM5" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "Q08DM5", "url": "https://www.uniprot.org/uniprotkb/Q08DM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 141, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DM5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DS5-1", "uniprot_ac": "Q08DS5", "uniprot_id": "NMD3_BOVIN", "mass": { "chemical_mass": 57748.0, "monoisotopic_mass": 57748.0 }, "refseq": { "ac": "NP_001068888", "name": "60S ribosomal export protein NMD3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068888" }, "gene_names": [ { "name": "NMD3", "type": "recommended", "evidence": [ { "id": "Q08DS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ] }, { "name": "NMD3", "type": "synonym", "evidence": [ { "id": "NP_001068888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068888" } ] } ], "protein_names": [ { "name": "60S ribosomal export protein NMD3", "type": "recommended", "evidence": [ { "id": "Q08DS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DS5/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal export protein NMD3", "type": "synonym", "evidence": [ { "id": "NP_001068888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068888" } ] }, { "name": "NMD3 homolog", "type": "synonym", "evidence": [ { "id": "NP_001068888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068888" } ] } ], "function": [ { "annotation": "Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5#function" }, { "database": "UniProtKB", "id": "Q96D46", "url": "https://www.uniprot.org/uniprotkb/Q96D46#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NMD3", "url": "https://www.uniprot.org/uniprotkb/Q08DS5", "locus": { "chromosome": "1", "start_pos": 106135036, "end_pos": 106187628, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016228", "url": "https://www.ensembl.org/id/ENSBTAG00000016228" } ] } } ], "crossref": [ { "id": "Q08DS5", "url": "https://alphafold.ebi.ac.uk/entry/Q08DS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016228", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016228", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509871", "url": "https://www.ncbi.nlm.nih.gov/gene/509871", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509871", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509871", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VILVRKH", "url": "https://omabrowser.org/oma/group/VILVRKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q08DS5", "url": "https://www.orthodb.org/?gene=Q08DS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12746:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12746:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21192", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21192", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001068888", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068888", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DS5-1", "url": "https://www.uniprot.org/uniprotkb/Q08DS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYMTDPVKHTPGHILCCDCGVPISPNPANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWVQCALESRDLLALCLKKIKAPLSKVRLVDASFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQPQMCGDCHRVEAKDFWKAVVQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPTRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSVIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVMECSIVQDIKRSAGAGMISKKHTLGEVWVQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLVNCNLNDEHVNKMKSDRVPDVVLIKKSYDRTRRQRRRNWKLKELARDRENTDTDDERQYQDFLEDLEEDEAIRKNVNIYRDSTIPVESDTDDEGAPRISLAEMLEDLHISQDATGGEGESMMT", "length": 503, "header": "sp|Q08DS5-1|NMD3_BOVIN Isoform 1 of 60S ribosomal export protein NMD3 OS=Bos taurus OX=9913 GN=NMD3 PE=2 SV=1 CANONICAL=Q08DS5-1" }, "isoforms": [ { "isoform_ac": "Q08DS5-1", "url": "https://www.uniprot.org/uniprotkb/Q08DS5/entry#Q08DS5-1", "sequence": { "sequence": "MEYMTDPVKHTPGHILCCDCGVPISPNPANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWVQCALESRDLLALCLKKIKAPLSKVRLVDASFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQPQMCGDCHRVEAKDFWKAVVQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPTRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSVIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVMECSIVQDIKRSAGAGMISKKHTLGEVWVQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLVNCNLNDEHVNKMKSDRVPDVVLIKKSYDRTRRQRRRNWKLKELARDRENTDTDDERQYQDFLEDLEEDEAIRKNVNIYRDSTIPVESDTDDEGAPRISLAEMLEDLHISQDATGGEGESMMT", "length": 503, "header": "sp|Q08DS5-1|NMD3_BOVIN Isoform 1 of 60S ribosomal export protein NMD3 OS=Bos taurus OX=9913 GN=NMD3 PE=2 SV=1 CANONICAL=Q08DS5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 258, "end_pos": 258, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "site_lbl": "Ser258" }, { "start_pos": 433, "end_pos": 433, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "site_lbl": "Thr433" }, { "start_pos": 468, "end_pos": 468, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "site_lbl": "Ser468" }, { "start_pos": 470, "end_pos": 470, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "site_lbl": "Thr470" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509871", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VFP0-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "NMD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEYMTESINRTPGHILCCDCGVPISPNPANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVRLVDASFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVVQVRQKTVHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPTRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSVIHLIDPNTLQVADIDGNTFWTHPFNSLCHPKQLEEFIVMECSIVRDLKRSAGAGMISKKHTLGEVWVQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMKSDRIPDVVLIKKNYDRTKRQRRRNWKLKELARDRENMDTDNERQYQDFLEDLEEDEAIRKNVNIYRDPTIPVESDTDDEGAPRISLAEMLEDLHISQDATGEEGELMMT", "length": 503 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B1WC44-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "Nmd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEYMTESVDRSPGHILCCECGVPISPNPANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGTVPCRYKSSQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSIVRDLKRNAGAGVISKKHTLGEVWIQKTSEMDTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMKSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDREDMDTDDERQYQDFLEDLEEDETIRKNVNIYRDSTVPVESDTDDEGAPRISLAEMLEDLRISQDATGEEGASMMS", "length": 503 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BTL9-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "NMD3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEYLAAPAAPTQGSILCCHCGVPIPPNPANMCVGCLRARVDITEGIPKQLSVSFCKQCERYLQPPGTWIQCALESRELLALCLKKIKASLSKVRLIDAGFIWTEPHSKRLKLKLTVQKEVINGAVLQQVFVVEYLIQSQMCEDCHRIEAKDFWKAVVQVRQKTLHKKTFYYLEQLILKHRLHQNTLRIKEIHDGLDFYYSSKQHAQKMVDFLQCTVPSRSKSSQRLTSHDVHSNVYNYKSTFSVEIVPVCKDNVVCLSPKLAQSLGNMSQICVCIRVTSTVHLIDPSTLQIAEIDGNTYWRHPFNSLFNPKQLEEFIVMDINRVQEKKKPAGAGARSNKHTLAEAWVKKTSELNTDHQYFCCTHLGHILNPGDLVLGFDLANCNLNDEFVNKMSPHNIPDVVLIKKSYDRAKRQHRRNWKLKELERDREGTDTDDERQYQDFLEDLEEDEAIRKNVNIYRNADIPVESDTDDDGAPRISLAEMLEDLHISEDATGGEGANMMTE", "length": 504 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O46050-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "Nmd3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDHEYVGVSPLGAADGKGAGSNAVILCCECGVAIQPNPANMCVTCLRNHVDITENIPKQAVLHFCRNCERYLQPPNEWIQAALESRELLAICLKKLKGLKEVKLVDAGFIWTEQHSKRIKVKLTVHGEIIGGTMLQQVFVVEFTVQNQMCNDCHRTEAKDFWRCLVQVRQRAENKKTFYYLEQLILKHKAHENTLGIKPEHGGLDFFYANDNHARRMVDFLLTMVPGKVTTSKRLISHDIHSNNYNYKYNWSVEIAPVSKDSAVCLSKKLRHQLGNLSPLVLVNRVSSSIHLIDPLTAQIAELTSQVYFRAPFEAVCNPKQLVEYVVMDIDVIMEKDRKTYPGQGQVSFKHALCDIWVVRASELGINDNPIHTRSHLGHLLKVGDSVMGYNTGEANINDLEFDKLSSDEIPDVILVRKHYDRQTRLSQRVWKIKHLAAEATDERSKYDYHEFLDDLEENEDIRGQVNIYRDTNKTIPIEVQAAGGDVPQITLEEMLEDMTLECADDEMGEEGGADDTEPQL", "length": 521 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P38861-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "NMD3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEFTPIDPHQHQNAATLLCCNCGTPIDGSTGLVMCYDCIKLTVDITQGIPREANISFCRNCERFLQPPGQWIRAELESRELLAICLRRLKGLTKVRLVDASFIWTEPHSRRIRIKLTVQGEAMTNTIIQQTFEVEYIVIAMQCPDCARSYTTNTWRATVQIRQKVPHKRTFLFLEQLILKHNAHVDTISISEAKDGLDFFYAQKNHAVKMIDFLNAVVPIKHKKSEELISQDTHTGASTYKFSYSVEIVPICKDDLVVLPKKLAKSMGNISQFVLCSKISNTVQFMDPTTLQTADLSPSVYWRAPFNALADVTQLVEFIVLDVDSTGISRGNRVLADITVARTSDLGVNDQVYYVRSHLGGICHAGDSVMGYFIANSNYNSDLFDGLNIDYVPDVVLVKKLYQRKSKKSRHWKLKRMAKEHKDIDASLDYNSRAQKQEMERAEKDYELFLQELEEDAELRQSVNLYKNREANVPPEEHEMDEDEDEDAPQINIDELLDELDEMTLEDGVENTPVESQQ", "length": 518 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55BF2-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "nmd3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYIPQVKQANILCCMCGVLIPANPSNMCVDCIKSQVDITEGIPKQLTIQWCRGCARYLQPPNHWAIAELESRELLTICIKRIKGLNKVKLVDAGWVWTEPHSKRLKVKLTIQKEVFTSAILQQIFIIEFIVQGQQCDKCQKFEAKDTWNSVVQLRQKVDHKRTFLYIEQLILKHNAHSQTLNIKEKPDGLDFFFSNRNHAMKFVEFISAITPVKTKKSEQLISSDEQNNAANYKYTFSVEIVPLSKDDIVCLPPKIAHQLGNMGPLVVVTKVSNLIHFIDPNTLHTGEISALTFWNSPFRALSSYKQLVEFTVLDVNLTGATRGRYALSDIQLMRSADFGANDNIYDIRSHLGNILNPGDLALGYDVASSNFPDSDLAGMKKNQQLPDFVLVKKTYPSKNDFRFKRHWYFKEIPKEGIENPKKFEIDQMERDREEFLREIEADPELRSKINIYKEADAANILQQRIKKMQEHGIDEDAIKEELALDGLLDDMVNNLTINDEEFEDEEDQEGEDDDEEYDDEDEDDDMME", "length": 530 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BLF0-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "nmd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEYMQAPPSSSHGNILCCTCGVPIPPNPANMCVSCLRTQVDISEGIPKQVTIHFCRQCERYLQPPGSWVQCALESRELLALCLKKLKASMSKVRLIDAGFLWTEPHSKRIKIKLTIQKEVMNGAILQQVFTVEFVVQGQMCEDCHRVEAKDFWKAVVQVRQKTVHKKTFYYLEQLILKHKLHQNTVRIKEIHEGIDFYYATKQHAQKMVDFLQCTVPCRSKASQRLISHDVHSNTYNYKSTFSVEIVPVCKDNVVCLSPRLAQSLGNMGQVCVCVRVTSSIHLIDPNTLQIAEVDGSTFWRHPFNSLCSPRQLEEFIIMDIDIIRDQRLGAGAGLKSNKHTLAEVWVQKTSEMDSSHQYHCRTFMGHLLNIGDLVLGFDFANANINDEFLNKMNPQHVPDVVLIKKSYDRMKRARKRVWKLKEMDREKDAADTDDERQYTEFLEDLEEDEMLRKNINIFRDASKIPVEESDTDDDGAPRISLAEMLEDLSLSDATGGEGADMMTD", "length": 505 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96D46-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "NMD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEYMAESTDRSPGHILCCECGVPISPNPANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSAIHLIDPNTLQVADIDGSTFWSHPFNSLCHPKQLEEFIVMECSIVQDIKRAAGAGMISKKHTLGEVWVQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARERENMDTDDERQYQDFLEDLEEDEAIRKNVNIYRDSAIPVESDTDDEGAPRISLAEMLEDLHISQDATGEEGASMLT", "length": 503 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99L48-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "Nmd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEYMAESIEHSPGHILCCECGVPISPNPANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGIVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMSQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSTVRDLKRSAGAGVISKKHTLGEVWIQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEYVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDRENMDTDDERQYQDFLEDLEEDEAIRKHVNIYRDATIPVESDTDDEGAPRISLAEMLEDLHISQDATGEEGASMMS", "length": 503 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SI58-1", "protein_name": "60S ribosomal export protein NMD3", "gene_name": "NMD3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSVMDESGMFNVQQTIGSVLCCKCGVPMAPNAANMCVNCLRSEVDITEGLQKSIQIFYCPECTCYLQPPKTWIKCQWESKELLTFCIKRLKNLNKVKLKNAEFVWTEPHSKRIKVKLTVQAEVLNGAVLEQSYPVEYTVRDNLCESCSRFQANPDQWVASIQLRQHVSHRRTFFYLEQLILRHDAASRAIRIQQVDQGIDFFFGNKSHANSFVEFLRKVVPIEYRQDQQLVSHDVKSSLYNYKYTYSVKICPVCREDLVCLPSKVASGLGNLGPLVVCTKVSDNITLLDPRTLRCAFLDARQYWRSGFRSALTSRQLVKYFVFDVEPPVGEATVGGQKYALSYVQIARESDIGKMFYVQTHLGHILKPGDQALGYDIYGANVNDNEMEKYRLSVKNGLPEAILIKKCYEEQRERKQKKSRNWKLKSLPMEMDDSRGRVDPEKTDKEYEEFLRDLEENPELRFNISLYRDKDYQASETASMTDGEGAPSVPIEELLADLDLSFEEEDDDDEDDMAAE", "length": 516 }, "evidence": [ { "id": "Q08DS5", "url": "https://omabrowser.org/oma/group/Q08DS5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "Q08DS5", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DS5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 503, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DS5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DS5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q08DS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear and nucleolar localization signal", "eco_id": "ECO_0000250", "start_pos": 405, "end_pos": 422, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q08DS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DS5" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Nuclear export signal", "eco_id": "ECO_0000250", "start_pos": 480, "end_pos": 489, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 258, 433, 468, 470 ], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DT6-1", "uniprot_ac": "Q08DT6", "uniprot_id": "RM47_BOVIN", "mass": { "chemical_mass": 29580.0, "monoisotopic_mass": 29580.0 }, "refseq": { "ac": "NP_001070369", "name": "large ribosomal subunit protein uL29m", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070369" }, "gene_names": [ { "name": "MRPL47", "type": "recommended", "evidence": [ { "id": "Q08DT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DT6" } ] }, { "name": "MRPL47", "type": "synonym", "evidence": [ { "id": "NP_001070369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070369" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL29m", "type": "recommended", "evidence": [ { "id": "Q08DT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DT6/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L47, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001070369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070369" }, { "id": "Q08DT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DT6/entry#names_and_taxonomy" } ] }, { "name": "L47mt", "type": "synonym", "evidence": [ { "id": "NP_001070369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070369" }, { "id": "Q08DT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DT6/entry#names_and_taxonomy" } ] }, { "name": "MRP-L47", "type": "synonym", "evidence": [ { "id": "NP_001070369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070369" }, { "id": "Q08DT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DT6/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein uL29m", "type": "synonym", "evidence": [ { "id": "NP_001070369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070369" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DT6", "url": "https://www.uniprot.org/uniprotkb/Q08DT6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MRPL47", "url": "https://www.uniprot.org/uniprotkb/Q08DT6", "locus": { "chromosome": "1", "start_pos": 87536139, "end_pos": 87518793, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002462", "url": "https://www.ensembl.org/id/ENSBTAG00000002462" } ] } } ], "crossref": [ { "id": "Q08DT6", "url": "https://alphafold.ebi.ac.uk/entry/Q08DT6", "database": "AlphaFoldDB", "categories": [] }, { "id": "534317", "url": "https://www.ncbi.nlm.nih.gov/gene/534317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534317", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534317", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q08DT6", "url": "https://www.orthodb.org/?gene=Q08DT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21183:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21183:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070369", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070369", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q08DT6", "url": "https://www.uniprot.org/uniprotkb/Q08DT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DT6-1", "url": "https://www.uniprot.org/uniprotkb/Q08DT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAASLAVFCRRVSAALKASTSLISSQTLASTGCRFSLSLLTKNTPNVTSFHQCRLLQTTLSRRGLEEFFDDPKNWGEEKVKSGASWTCQQLRNKSNEDLHKLWYVLLKERNMLLTLEQEAKRQRLPMPSPERLEKVVDSMDALDKVVQEREDALRLLQTGQEKPRPGAWRRDIFGRIIWHKFKQWPIPWYLNKRYNRKRFFAMPYVERFVRLRIEKQARIKARKISLTQKKEKFLQKKFPHLSEAQKSSAA", "length": 252, "header": "sp|Q08DT6-1|RM47_BOVIN Isoform 1 of Large ribosomal subunit protein uL29m OS=Bos taurus OX=9913 GN=MRPL47 PE=2 SV=1 CANONICAL=Q08DT6-1" }, "isoforms": [ { "isoform_ac": "Q08DT6-1", "url": "https://www.uniprot.org/uniprotkb/Q08DT6/entry#Q08DT6-1", "sequence": { "sequence": "MAAASLAVFCRRVSAALKASTSLISSQTLASTGCRFSLSLLTKNTPNVTSFHQCRLLQTTLSRRGLEEFFDDPKNWGEEKVKSGASWTCQQLRNKSNEDLHKLWYVLLKERNMLLTLEQEAKRQRLPMPSPERLEKVVDSMDALDKVVQEREDALRLLQTGQEKPRPGAWRRDIFGRIIWHKFKQWPIPWYLNKRYNRKRFFAMPYVERFVRLRIEKQARIKARKISLTQKKEKFLQKKFPHLSEAQKSSAA", "length": 252, "header": "sp|Q08DT6-1|RM47_BOVIN Isoform 1 of Large ribosomal subunit protein uL29m OS=Bos taurus OX=9913 GN=MRPL47 PE=2 SV=1 CANONICAL=Q08DT6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534317", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534317", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "Q08DT6", "url": "https://www.uniprot.org/uniprotkb/Q08DT6" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q08DT6", "url": "https://www.uniprot.org/uniprotkb/Q08DT6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q08DT6", "url": "https://www.uniprot.org/uniprotkb/Q08DT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "Q08DT6", "url": "https://www.uniprot.org/uniprotkb/Q08DT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, 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"MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSIDVADNRGWMPIHEASYHNSVECLRMLIRADSSENYIKTKTFEGFCALHLAASQGHWKIIQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLRYGANVNGSHSMCGWNALHQASFQGNAEIIKLLLKKGANKECQDDFGITPLFVAAQYGKLESLSILISSGADVNCQALDKATPLFIAAQEGHTECVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTKILDLLIPLTNRVCDTGPNKVSPVYSAVLGGHEECLEMLLQSGYSPDAQMCLVFGFSSPLCMAFQKDCDFFGIVNILLKYGAQLNELHLAYCLKYERFSVFRYFLKKCCPSTPWDHISEFINHAIKAQTKYKEWLPSLLLAGFDPLNLLCSSWIDSVSDDILIFTLEFTNWRRLPPAVEKMLSARASNSSWALQQHIASVPSLTHLCRLEIWSHLKLEHLQSDGFIRQLPLPRSLHDYLLYAEVLRMNEVPELAVFQDGEISETT", "length": 525, "header": "sp|Q08DV6-1|ASB3_BOVIN Isoform 1 of Ankyrin repeat and SOCS box protein 3 OS=Bos taurus OX=9913 GN=ASB3 PE=2 SV=1 CANONICAL=Q08DV6-1" }, "isoforms": [ { "isoform_ac": "Q08DV6-1", "url": "https://www.uniprot.org/uniprotkb/Q08DV6/entry#Q08DV6-1", "sequence": { "sequence": "MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSIDVADNRGWMPIHEASYHNSVECLRMLIRADSSENYIKTKTFEGFCALHLAASQGHWKIIQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLRYGANVNGSHSMCGWNALHQASFQGNAEIIKLLLKKGANKECQDDFGITPLFVAAQYGKLESLSILISSGADVNCQALDKATPLFIAAQEGHTECVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTKILDLLIPLTNRVCDTGPNKVSPVYSAVLGGHEECLEMLLQSGYSPDAQMCLVFGFSSPLCMAFQKDCDFFGIVNILLKYGAQLNELHLAYCLKYERFSVFRYFLKKCCPSTPWDHISEFINHAIKAQTKYKEWLPSLLLAGFDPLNLLCSSWIDSVSDDILIFTLEFTNWRRLPPAVEKMLSARASNSSWALQQHIASVPSLTHLCRLEIWSHLKLEHLQSDGFIRQLPLPRSLHDYLLYAEVLRMNEVPELAVFQDGEISETT", "length": 525, "header": "sp|Q08DV6-1|ASB3_BOVIN Isoform 1 of Ankyrin repeat and SOCS box protein 3 OS=Bos taurus OX=9913 GN=ASB3 PE=2 SV=1 CANONICAL=Q08DV6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540802", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q08DV6", "url": "https://www.uniprot.org/uniprotkb/Q08DV6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q08DV6", "url": "https://www.uniprot.org/uniprotkb/Q08DV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DV6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 525, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DV6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DV6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q08DV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DV6" }, { "id": "PRU00194", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000255", "start_pos": 441, "end_pos": 505, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 448, "end_pos": 450 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q08DX0-1", "uniprot_ac": "Q08DX0", "uniprot_id": "SNX29_BOVIN", "mass": { "chemical_mass": 91337.0, "monoisotopic_mass": 91337.0 }, "refseq": { "ac": "NP_001070330", "name": "sorting nexin-29", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070330" }, "gene_names": [ { "name": "SNX29", "type": "recommended", "evidence": [ { "id": "Q08DX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ] }, { "name": "SNX29", "type": "synonym", "evidence": [ { "id": "NP_001070330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070330" } ] } ], "protein_names": [ { "name": "Sorting nexin-29", "type": "recommended", "evidence": [ { "id": "Q08DX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DX0/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-29", "type": "synonym", "evidence": [ { "id": "NP_001070330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070330" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SNX29", "url": "https://www.uniprot.org/uniprotkb/Q08DX0", "locus": { "chromosome": "25", "start_pos": 11276292, "end_pos": 10682180, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000026371", "url": "https://www.ensembl.org/id/ENSBTAG00000026371" } ] } } ], "crossref": [ { "id": "Q08DX0", "url": "https://alphafold.ebi.ac.uk/entry/Q08DX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07277", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07277", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518366", "url": "https://www.ncbi.nlm.nih.gov/gene/518366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518366", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q08DX0", "url": "https://www.orthodb.org/?gene=Q08DX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DX0-1", "url": "https://www.uniprot.org/uniprotkb/Q08DX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGTQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTAAAIKQAAGFASKTETEPVFWFYVKEVLSKHELQRFHALRHIASDVGRGRAWLRCALNENSLERYLHMLLADRGRLSTFYEDWAFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGVSSLFREITASSAVSILSRAEQETDPLPVVSKHVSADAKCKRERKKKKKVTNIISFDDEEDEQSSGDVFKKIPGAGESSEENSDRSSINIMSAFESPFGPNSNGSQGSNSWKIDSLSLNGEFGYQKLDVKSIDDEDADENEDDVCGSMPGRKRPGHSESPEKPLDAGTCLSQMHGWAPLQVLHGHAEVLFPVSGVGSYGPADAPLGSLENGTGPEDHILPEPGPRYSVEASPPGQESPLSSLLPSASVPESMTVSDLRQAIVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERHVTKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVVPNLWNIDGEVTVPEQKPGEVAEELTSSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRTLHHKLQNKYPQVRAFNFPPKKAIGNKDAKFVEERRKQLQTYLRSVMNKVIQAVPEFTASPQKETLTQLMPFFVDITPPGDALTKNSRPKVASRFPKLARGHPRETRNVEPQSGDL", "length": 817, "header": "sp|Q08DX0-1|SNX29_BOVIN Isoform 1 of Sorting nexin-29 OS=Bos taurus OX=9913 GN=SNX29 PE=2 SV=1 CANONICAL=Q08DX0-1" }, "isoforms": [ { "isoform_ac": "Q08DX0-1", "url": "https://www.uniprot.org/uniprotkb/Q08DX0/entry#Q08DX0-1", "sequence": { "sequence": "MSGTQNNDMKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTAAAIKQAAGFASKTETEPVFWFYVKEVLSKHELQRFHALRHIASDVGRGRAWLRCALNENSLERYLHMLLADRGRLSTFYEDWAFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGVSSLFREITASSAVSILSRAEQETDPLPVVSKHVSADAKCKRERKKKKKVTNIISFDDEEDEQSSGDVFKKIPGAGESSEENSDRSSINIMSAFESPFGPNSNGSQGSNSWKIDSLSLNGEFGYQKLDVKSIDDEDADENEDDVCGSMPGRKRPGHSESPEKPLDAGTCLSQMHGWAPLQVLHGHAEVLFPVSGVGSYGPADAPLGSLENGTGPEDHILPEPGPRYSVEASPPGQESPLSSLLPSASVPESMTVSDLRQAIVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERHVTKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVVPNLWNIDGEVTVPEQKPGEVAEELTSSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYAEFRTLHHKLQNKYPQVRAFNFPPKKAIGNKDAKFVEERRKQLQTYLRSVMNKVIQAVPEFTASPQKETLTQLMPFFVDITPPGDALTKNSRPKVASRFPKLARGHPRETRNVEPQSGDL", "length": 817, "header": "sp|Q08DX0-1|SNX29_BOVIN Isoform 1 of Sorting nexin-29 OS=Bos taurus OX=9913 GN=SNX29 PE=2 SV=1 CANONICAL=Q08DX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 269, "end_pos": 269, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ], "site_lbl": "Ser269" }, { "start_pos": 292, "end_pos": 292, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ], "site_lbl": "Ser292" }, { "start_pos": 293, "end_pos": 293, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ], "site_lbl": "Ser293" }, { "start_pos": 331, "end_pos": 331, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ], "site_lbl": "Ser331" }, { "start_pos": 345, "end_pos": 345, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ], "site_lbl": "Ser345" }, { "start_pos": 451, "end_pos": 451, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": "https://www.uniprot.org/uniprotkb/Q08DX0" } ], "site_lbl": "Ser451" }, { "start_pos": 641, "end_pos": 641, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DX0", "url": 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"R-BTA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015328774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015328774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0F7RPV8", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0F7RPV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLVYLFLGPMTLLLLAGCGCVISTSSENLRTFVGCAVREFTFLAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAHHRVCTYNETKQVTVKLPNCAPGVDPFYSYPVAVRCDCGACSTATTECETI", "length": 130, "header": "tr|A0A0F7RPV8-1|A0A0F7RPV8_BOVIN Isoform 1 of Glycoprotein hormone beta-5 OS=Bos taurus OX=9913 GN=GPHB5 PE=3 SV=1 CANONICAL=A0A0F7RPV8-1" }, "isoforms": [ { "isoform_ac": "A0A0F7RPV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8/entry", "sequence": { "sequence": "MRLVYLFLGPMTLLLLAGCGCVISTSSENLRTFVGCAVREFTFLAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAHHRVCTYNETKQVTVKLPNCAPGVDPFYSYPVAVRCDCGACSTATTECETI", "length": 130, "header": "tr|A0A0F7RPV8-1|A0A0F7RPV8_BOVIN Isoform 1 of Glycoprotein hormone beta-5 OS=Bos taurus OX=9913 GN=GPHB5 PE=3 SV=1 CANONICAL=A0A0F7RPV8-1" }, "locus": { "chromosome": "10", "start_pos": 75581977, "end_pos": 75578166, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116549.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116549.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091237.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091237.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539408", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539408", "resource": "KEGG Pathway" }, { "id": "R-BTA-375281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375281", "resource": "Reactome", "description": "Hormone ligand-binding receptors" }, { "id": "R-BTA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1WCF1-1", "protein_name": "Glycoprotein hormone beta-5", "gene_name": "GPHB5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLAHLVLGPMILLLLAGCACVLSTSSGNLRTFVGCAVREFTFLAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAYHRVCTYNETKQVTVKLPNCAPGVDPFYTYPMAVRCDCGACSTATTECETI", "length": 130 }, "evidence": [ { "id": "A0A0F7RPV8", "url": "https://omabrowser.org/oma/group/A0A0F7RPV8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MBR3-1", "protein_name": "Glycoprotein hormone beta-5", "gene_name": "Gphb5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLAYLVLGAMTLLLLGGYDSVLSTSGRNLHTFVGCAVREFTFLAKKPGCRGLRITTDACWGRCKTWEKPILEPPYIEAHHRVCTYNETKQVTVKLPNCAPGVDPFYTYPMAVRCDCGTCSTATTECETI", "length": 130 }, "evidence": [ { "id": "A0A0F7RPV8", "url": "https://omabrowser.org/oma/group/A0A0F7RPV8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q812B2-1", "protein_name": "Glycoprotein hormone beta-5", "gene_name": "Gphb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVYLVLGAVALLLLGGPDSVLSSSSGNLHTFVGCAVREFTFMAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAYHRVCTYNETRQVTVKLPNCAPGVDPFYTYPMAVRCDCGACSTATTECETI", "length": 130 }, "evidence": [ { "id": "A0A0F7RPV8", "url": "https://omabrowser.org/oma/group/A0A0F7RPV8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86YW7-1", "protein_name": "Glycoprotein hormone beta-5", "gene_name": "GPHB5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLAFLFLGPMALLLLAGYGCVLGASSGNLRTFVGCAVREFTFLAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAHHRVCTYNETKQVTVKLPNCAPGVDPFYTYPVAIRCDCGACSTATTECETI", "length": 130 }, "evidence": [ { "id": "A0A0F7RPV8", "url": "https://omabrowser.org/oma/group/A0A0F7RPV8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GK45-1", "protein_name": "Glycoprotein hormone beta-5", "gene_name": "GPHB5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLPCVTLGALLLLLLAGHGGTETSAIDLRTFIGCAVREFTFLAKKPGCKALRITTDACWGRCETWERPLLHPPYIESYHRVCTYNETKLVTVMLPKCGPGVDPFYTYPVAIRCNCDFCSTATTECETA", "length": 129 }, "evidence": [ { "id": "A0A0F7RPV8", "url": "https://omabrowser.org/oma/group/A0A0F7RPV8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0F7RPV8", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A0F7RPV8", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A0F7RPV8", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A0F7RPV8", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A0F7RPV8", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8" } ], "pmid": "" }, { "name": "thyrotropin-releasing hormone receptor binding", "id": "GO:0031531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031531", "evidence": [ { "database": "UniProtKB", "id": "A0A0F7RPV8", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A0F7RPV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0F7RPV8" }, { "id": "PF00007", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoprotein hormone subunit beta", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 128, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A140T832-1", "uniprot_ac": "A0A140T832", "uniprot_id": "A0A140T832_BOVIN", "mass": { "chemical_mass": 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The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A140T832", "url": "https://www.uniprot.org/uniprotkb/A0A140T832#function" }, { "database": "UniProtKB", "id": "ARBA00045441", "url": "https://www.uniprot.org/uniprotkb/ARBA00045441#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T832", "url": "https://www.uniprot.org/uniprotkb/A0A140T832" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPS17", "url": 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Classification" ] }, { "id": "HTEHIEV", "url": "https://omabrowser.org/oma/group/HTEHIEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T832", "url": "https://www.orthodb.org/?gene=A0A140T832", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10732:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10732:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1799339", "url": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A140T832", "url": "https://www.uniprot.org/uniprotkb/A0A140T832", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T832-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T832-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQINSSFRPLDADGPSTFPFYFASAPLGVAVVRWSRLSASQARRKRLSGLRFIGLSCASCFLFYQGPANMGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 205, "header": "tr|A0A140T832-1|A0A140T832_BOVIN Isoform 1 of Small ribosomal subunit protein eS17 OS=Bos taurus OX=9913 GN=RPS17 PE=3 SV=2 CANONICAL=A0A140T832-1" }, "isoforms": [ { "isoform_ac": "A0A140T832-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T832/entry", "sequence": { "sequence": "MGQINSSFRPLDADGPSTFPFYFASAPLGVAVVRWSRLSASQARRKRLSGLRFIGLSCASCFLFYQGPANMGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 205, "header": "tr|A0A140T832-1|A0A140T832_BOVIN Isoform 1 of Small ribosomal subunit protein eS17 OS=Bos taurus OX=9913 GN=RPS17 PE=3 SV=2 CANONICAL=A0A140T832-1" }, "locus": { "chromosome": "21", "start_pos": 22842669, "end_pos": 22839099, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000814.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000814.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000814.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000814.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-BTA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-BTA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-BTA-72689", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-BTA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-BTA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-BTA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-BTA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-BTA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-BTA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-BTA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "P02407-1", "protein_name": "Small ribosomal subunit protein eS17A", "gene_name": "RPS17A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGRVRTKTVKRASKALIERYYPKLTLDFQTNKRLCDEIATIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSRSNGVLNVDNQTSDLVKSLGLKLPLSVINVSAQRDRRYRKRV", "length": 136 }, "evidence": [ { "id": "A0A140T832", "url": "https://omabrowser.org/oma/group/A0A140T832/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A140T832", "url": "https://omabrowser.org/oma/group/A0A140T832/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08636-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "RPS17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAL", "length": 135 }, "evidence": [ { "id": "A0A140T832", "url": "https://omabrowser.org/oma/group/A0A140T832/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P08708-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "RPS17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGPV", "length": 135 }, "evidence": [ { "id": "A0A140T832", "url": "https://omabrowser.org/oma/group/A0A140T832/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P63274-1", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A140T832", "url": "https://www.uniprot.org/uniprotkb/A0A140T832" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A140T832", "url": "https://www.uniprot.org/uniprotkb/A0A140T832" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A140T832-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 205, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"https://www.uniprot.org/uniprotkb/A0A140T834" } ] } ], "protein_names": [ { "name": "Kelch domain-containing protein 8B", "type": "recommended", "evidence": [ { "id": "A0A140T834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T834/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A140T834", "url": "https://www.uniprot.org/uniprotkb/A0A140T834#function" }, { "database": "UniProtKB", "id": "ARBA00045748", "url": "https://www.uniprot.org/uniprotkb/ARBA00045748#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T834", "url": "https://www.uniprot.org/uniprotkb/A0A140T834" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLHDC8B", "url": "https://www.uniprot.org/uniprotkb/A0A140T834", "locus": { "chromosome": "22", "start_pos": 50854958, "end_pos": 50859766, "strand": "+", "evidence": [ { "database": 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"PTHR46260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46260:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46260:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A140T834", "url": "https://www.uniprot.org/uniprotkb/A0A140T834", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T834-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T834-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATGGGRAFAWQVFPPMPTCRVYGTVAFQDGHLLVLGGCGRAGLPLDTAETLDMASHTWVALAPLPTARAGAAAVVLGKQVLVVGGVDEGQSPVAAVEAFLADEGRWERRATLPQAAMGVATVERDGMVYALGGMGPDTAPQAQVRVYEPRRDCWLSLPSMPTPCYGASTFLHGNKIYVLGAPIPLAGGRQGKLPVTAFEAFDLEARTWTRHPSLPSRRAFAGCAMAEGSVFSLGGLQQPGPHNFYSRPHFVNTVEMFDLEHGSWTKLPRSLRMRDKRADFVVGSLGDHVVAIGGLGNQPCPLGSVEGFSLARRRWEALPAMPTARCSCSSLQAGPRLFAIGGVAQGPSQAVEALCLRDGV", "length": 361, "header": "tr|A0A140T834-1|A0A140T834_BOVIN Isoform 1 of Kelch domain-containing protein 8B OS=Bos taurus OX=9913 GN=KLHDC8B PE=4 SV=2 CANONICAL=A0A140T834-1" }, "isoforms": [ { "isoform_ac": "A0A140T834-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T834/entry", "sequence": { "sequence": 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"table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A140T848-1", "uniprot_ac": "A0A140T848", "uniprot_id": "A0A140T848_BOVIN", "mass": { "chemical_mass": 92578.0, "monoisotopic_mass": 92578.0 }, "refseq": {}, "gene_names": [ { "name": "BCAR3", "type": "recommended", "evidence": [ { "id": "A0A140T848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T848" } ] } ], "protein_names": [ { "name": "BCAR3 adaptor protein, NSP family member", "type": "synonym", "evidence": [ { "id": "A0A140T848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T848/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T848", "url": "https://www.uniprot.org/uniprotkb/A0A140T848" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BCAR3", "url": "https://www.uniprot.org/uniprotkb/A0A140T848", "locus": { "chromosome": "3", "start_pos": 49912342, "end_pos": 49691045, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003245", "url": "https://www.ensembl.org/id/ENSBTAG00000003245" } ] } } ], "crossref": [ { "id": "A0A140T848", "url": "https://alphafold.ebi.ac.uk/entry/A0A140T848", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003245", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003245", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506231", "url": "https://www.ncbi.nlm.nih.gov/gene/506231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MDPAMEY", "url": "https://omabrowser.org/oma/group/MDPAMEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T848", "url": "https://www.orthodb.org/?gene=A0A140T848", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A140T848", "url": "https://www.uniprot.org/uniprotkb/A0A140T848", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T848-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T848-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8D6", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MN50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MN50-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFSRVGRSLVTGVPVLQFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAEKILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF", "length": 827, "header": "tr|A0A140T848-1|A0A140T848_BOVIN Isoform 1 of BCAR3 adaptor protein, NSP family member OS=Bos taurus OX=9913 GN=BCAR3 PE=4 SV=2 CANONICAL=A0A140T848-1" }, "isoforms": [ { "isoform_ac": "A0A140T848-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T848/entry", "sequence": { "sequence": "MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFSRVGRSLVTGVPVLQFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAEKILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF", "length": 827, "header": "tr|A0A140T848-1|A0A140T848_BOVIN Isoform 1 of BCAR3 adaptor protein, NSP family member OS=Bos taurus OX=9913 GN=BCAR3 PE=4 SV=2 CANONICAL=A0A140T848-1" }, "locus": { "chromosome": "3", "start_pos": 49911898, "end_pos": 49792619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004211.8", "url": "https://www.ensembl.org/id/ENSBTAT00000004211.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004211.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004211.6" } ] } }, { "isoform_ac": "A0A140T8D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D6/entry", "sequence": { "sequence": "MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAEKILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF", "length": 826, "header": "tr|A0A140T8D6-1|A0A140T848_BOVIN Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Bos taurus OX=9913 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A140T848-1" }, "locus": { "chromosome": "3", "start_pos": 49911898, "end_pos": 49792619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063777.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063777.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055991.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055991.1" } ] } }, { "isoform_ac": "A0A3Q1MN50-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN50/entry", "sequence": { "sequence": "MPKECNAFHALSAALCCFYHRRSFLGVKFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAEKILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF", "length": 735, "header": "tr|A0A3Q1MN50-1|A0A140T848_BOVIN Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Bos taurus OX=9913 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A140T848-1" }, "locus": { "chromosome": "3", "start_pos": 49911898, "end_pos": 49857927, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073790.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073790.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070920.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070920.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZIR2-1", "protein_name": "BCAR3 adaptor protein, NSP family member", "gene_name": "BCAR3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPRAVLYVSRRPAGSAPAELQLVLAESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 852 }, "evidence": [ { "id": "A0A140T848", "url": "https://omabrowser.org/oma/group/A0A140T848/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZAZ5-1", "protein_name": "Breast cancer anti-estrogen resistance protein 3 homolog", "gene_name": "Bcar3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGKFASLPRHMPVNHQFPLASSMDLLSSKSPLAEHRTEAYPDVSIHGTLPRKKKGPPPIRSCDSASHMGTLPHSKSPRQSSPLTQDLILEKPLPDWKGDSFAFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTSPGRGREGSFAEGRPDVVKRLSLTTGGIQARDHSLPRGNLLRNKDKSGSQPACLDHVQDRKAATLKAHQSESHLPIGCKLPPQSPSVDTSPCPNSPVFRTGSEPTLSPALVRRFSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPPSPSPWLNSEANYCELNPAFAVGCDRGAKLLSQALDSHEMLLTAKQNGASGPRNSGINYSILDGDDQGRHWDPLAVQTDEGQEDETKFVPPVMETVSSFRPNDFESKLLPPENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDMKRSMGVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAMELKDTMGDLYSFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASSVSVPLLMPLVTLMERQAVTFEGTDMWEKNDESCEIMLSHLATARFMAEASESYRMNAERVLADFQPDEEMTEILKTEFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL", "length": 825 }, "evidence": [ { "id": "A0A140T848", "url": "https://omabrowser.org/oma/group/A0A140T848/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R3Z4-1", "protein_name": "Breast cancer anti-estrogen resistance protein 3 isoform X1", "gene_name": "bcar3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/IPR016185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NGLVMYP", "url": "https://omabrowser.org/oma/group/NGLVMYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T850", "url": "https://www.orthodb.org/?gene=A0A140T850", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11130:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11130:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03917", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03917", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-174403", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174403", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005214785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13557", "url": "https://www.rhea-db.org/rhea/13557", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T850-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T850-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S395", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S395", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S395-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S395-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGU7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS83", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS83-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TX78", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TX78-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSALLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKILSNNPSKGLAMGIAKAWELYGSANAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRRFEDVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQLAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSCFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVIQCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 474, "header": "tr|A0A140T850-1|A0A140T850_BOVIN Isoform 1 of Glutathione synthetase OS=Bos taurus OX=9913 GN=GSS PE=3 SV=1 CANONICAL=A0A140T850-1" }, "isoforms": [ { "isoform_ac": "A0A140T850-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T850/entry", "sequence": { "sequence": "MATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSALLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKILSNNPSKGLAMGIAKAWELYGSANAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRRFEDVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQLAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSCFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVIQCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 474, "header": "tr|A0A140T850-1|A0A140T850_BOVIN Isoform 1 of Glutathione synthetase OS=Bos taurus OX=9913 GN=GSS PE=3 SV=1 CANONICAL=A0A140T850-1" }, "locus": { "chromosome": "13", "start_pos": 64256650, "end_pos": 64234616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004559.4", "url": "https://www.ensembl.org/id/ENSBTAT00000004559.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004559.3", "url": "https://www.ensembl.org/id/ENSBTAP00000004559.3" } ] } }, { "isoform_ac": "A0AAA9S395-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S395/entry", "sequence": { "sequence": "MGMSLEEEISEQKGATYAKTYGEKQRLDGITDSMDVGMATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSALLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKILSNNPSKGLAMGIAKAWELYGSANAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRRFEDVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQLAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSCFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVIQCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 511, "header": "tr|A0AAA9S395-1|A0A140T850_BOVIN Computationally mapped isoform of Glutathione synthetase OS=Bos taurus OX=9913 GN=GSS PE=3 SV=1 CANONICAL=A0A140T850-1" }, "locus": { "chromosome": "13", "start_pos": 64261975, "end_pos": 64234616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123163.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123163.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079575.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079575.1" } ] } }, { "isoform_ac": "A0AAA9TGU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGU7/entry", "sequence": { "sequence": "MATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSALLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKILSNNPSKGLAMGIAKAWELYGSAKNIHVIRRRFEDVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQLAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSCFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVIQCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 447, "header": "tr|A0AAA9TGU7-1|A0A140T850_BOVIN Computationally mapped isoform of Glutathione synthetase OS=Bos taurus OX=9913 GN=GSS PE=3 SV=1 CANONICAL=A0A140T850-1" }, "locus": { "chromosome": "13", "start_pos": 64256650, "end_pos": 64234616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102991.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102991.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095440.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095440.1" } ] } }, { "isoform_ac": "A0AAA9TS83-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS83/entry", "sequence": { "sequence": "MPVGMATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSALLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKILSNNPSKGLAMGIAKAWELYGSANAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRRFEDVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQLAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSCFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVIQCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 478, "header": "tr|A0AAA9TS83-1|A0A140T850_BOVIN Computationally mapped isoform of Glutathione synthetase OS=Bos taurus OX=9913 GN=GSS PE=3 SV=1 CANONICAL=A0A140T850-1" }, "locus": { "chromosome": "13", "start_pos": 64259161, "end_pos": 64234616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125032.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125032.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100201.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100201.1" } ] } }, { "isoform_ac": "A0AAA9TUP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUP1/entry", "sequence": { "sequence": "MATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSALLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRRFEDVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQLAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSCFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVIQCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 363, "header": "tr|A0AAA9TUP1-1|A0A140T850_BOVIN Computationally mapped isoform of Glutathione synthetase OS=Bos taurus OX=9913 GN=GSS PE=3 SV=1 CANONICAL=A0A140T850-1" }, "locus": { "chromosome": "13", "start_pos": 64256650, "end_pos": 64234616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107739.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107739.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100294.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100294.1" } ] } }, { "isoform_ac": "A0AAA9TX78-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX78/entry", "sequence": { "sequence": "MPVSVYQLNKRPTAGRDWNPRAVKKWGLLEGSIALKSESQVGMATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSALLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKILSNNPSKGLAMGIAKAWELYGSANAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRRFEDVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQLAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSCFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVIQCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 516, "header": "tr|A0AAA9TX78-1|A0A140T850_BOVIN Computationally mapped isoform of Glutathione synthetase OS=Bos taurus OX=9913 GN=GSS PE=3 SV=1 CANONICAL=A0A140T850-1" }, "locus": { "chromosome": "13", "start_pos": 64258156, "end_pos": 64234616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103666.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103666.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102070.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102070.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-174403", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174403", "resource": "Reactome", "description": "Glutathione synthesis and recycling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZRS0-1", "protein_name": "Glutathione synthetase", "gene_name": "GSS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQEPSSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNASFLEQTLSSTIKRDNFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQHNADGSSALKQIEINTISASFGGLASRTPAVHRHVLNVLSKTKEAAKILSNNPSKGLAMGIAKAWELYGSANALVLLVAQEKERNIFDQRAIENELLARNIHVIRRRFEDISEKGSLDQDRKLFMDGQEVAVVYFRDGYIPSQYSLQNWEARLLLERSRAVKCPDIATQLAGTKKVQQELSRVGVLEVLLPDQPEAVARLRATFAGLYSLDMGEEGDQAIAEAIAAPSHFVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVRCISELGIFGVYVRQGKTLVVNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 474 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P46413-1", "protein_name": "Glutathione synthetase", "gene_name": "Gss", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSWGSILQDEKQLEELAQQAIDRALAEGVLLRSAKNPSSSDVVTYAPFTLFPSPVPSTLLEQAYAVQMDFNILVDAVSQNSAFLEQTLSSTIKKDEYTARLFDIYKQVLKEGIAQTVFLGLNRSDYMFQCSADGSKALKQIEINTISASFGGLASRTPAVHRHVLNVLNKTNEASKILSNNPSKGLALGIAKAWELYGSANAVVLLIAQEKERNIFDQRAIENELLDRKIHVIRRRFEDVSERGSLDQNRRLFMEDQEVAVVYFRDGYMPSQYNAQNWEARLLLERSCAAKCPDIATQLAGTKKVQQELSRVGLLEALLPGQPEAVARLRATFAGLYSLDMGEEGDQAVAEALAAPSHFVLKPQREGGGNNFYGEEMVHALEQLKDSEERASYILMEKIEPEPFRNCLLRPGSPAQVVQCISELGIFGVYVRQGTTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 474 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P46416-1", "protein_name": "Glutathione synthetase, chloroplastic", "gene_name": "GSH2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSGCSSLSYSSSSTCNATVFSISSSPSSSSSLKLNPSSFLFQNPKTLRNQSPLRCGRSFKMESQKPIFDLEKLDDEFVQKLVYDALVWSSLHGLVVGDKSYQKSGNVPGVGLMHAPIALLPTAFPEAYWKQACNVTPLFNELIDRVSLDGKFLQDSLSRTKKVDVFTSRLLDIHSKMLERNKKEDIRLGLHRFDYMLDEETNSLLQIEMNTISCSFPGLSRLVSQLHQSLLRSYGDQIGIDSERVPINTSTIQFADALAKAWLEYSNPRAVVMVIVQPEERNMYDQHLLSSILREKHNIVVIRKTLAEVEKEGSVQEDETLIVGGQAVAVVYFRSGYTPNDHPSESEWNARLLIEESSAVKCPSIAYHLTGSKKIQQELAKPGVLERFLDNKEDIAKLRKCFAGLWSLDDSEIVKQAIEKPGLFVMKPQREGGGNNIYGDDVRENLLRLQKEGEEGNAAYILMQRIFPKVSNMFLVREGVYHKHQAISELGVYGAYLRSKDEVIVNEQSGYLMRTKIASSDEGGVAAGFGVLDSIYLI", "length": 539 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P48637-1", "protein_name": "Glutathione synthetase", "gene_name": "GSS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV", "length": 474 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51855-1", "protein_name": "Glutathione synthetase", "gene_name": "Gss", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSWGSILQDEKQLEELAKQAIDRALAEGVLLRSAQHPSSSDVVTYAPFTLFPSPVPSALLEQAYAVQMDFNILVDAVSQNPAFLEQTLSSTIKKDDYTARLFDIYKQVLKEGIAQTVFLGLNRSDYMFQCGADGSKALKQIEINTISASFGGLASRTPAVHRHVLNVLNKTKEASKILSNNPSKGLALGIAKAWELYGSANAVVLLIAQEKERNIFDQRAVENELLDRKIHVIRGRFEDVSERGSLDQNRRLFMDDQEVAVVYFRDGYMPSQYNSQNWEARLMLERSRAAKCPDIAIQLAGTKKVQQELSRVGLLEALLPGQPEAVARLRATFAGLYSLDMGEEGDQAIAEALAAPSHFVLKPQREGGGNNLYGEEMVQALEQLKDSEERASYILMEKIEPEPFRNCLLRPGSPAQVVQCISELGIFGVYVRQGTTLVMNKHVGHLLRTKAVEHADGGVAAGVAVLDNPYPV", "length": 474 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08220-1", "protein_name": "Glutathione synthetase GSH2", "gene_name": "GSH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAHYPPSKDQLNELIQEVNQWAITNGLSMYPPKFEENPSNASVSPVTIYPTPIPRKCFDEAVQIQPVFNELYARITQDMAQPDSYLHKTTEALALSDSEFTGKLWSLYLATLKSAQYKKQNFRLGIFRSDYLIDKKKGTEQIKQVEFNTVSVSFAGLSEKVDRLHSYLNRANKYDPKGPIYNDQNMVISDSGYLLSKALAKAVESYKSQQSSSTTSDPIVAFIVQRNERNVFDQKVLELNLLEKFGTKSVRLTFDDVNDKLFIDDKTGKLFIRDTEQEIAVVYYRTGYTTTDYTSEKDWEARLFLEKSFAIKAPDLLTQLSGSKKIQQLLTDEGVLGKYISDAEKKSSLLKTFVKIYPLDDTKLGREGKRLALSEPSKYVLKPQREGGGNNVYKENIPNFLKGIEERHWDAYILMELIEPELNENNIILRDNKSYNEPIISELGIYGCVLFNDEQVLSNEFSGSLLRSKFNTSNEGGVAAGFGCLDSIILY", "length": 491 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54E83-1", "protein_name": "Glutathione synthetase", "gene_name": "gshB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEEKLNDLKEQGIDWAFANGLIMIKKPTEEEAKNNVVNVTHVPFSLYPSKMNKKLFNEACKLAEDYNLLVHNISKDYDFLQNTLKDVFDDFTQMLLNIQRKVVKEGIKQKISLGIFRSDYMFHNKIEGEEERIYQVELNTISSSLAVVSNRVFNLHKYLIGRNDLNDNGYDLLNHPTNQSDKEISDSIALAHKLYNKEKSSVVLMIIQEGERNIYDQKGLEFQLWSNHSIKLIRRTMKEINQCAKLDEENGSVLIVDGMEISVAYYRAGYTPNDYTSSGGDEWKARLLIERSLAIKCPTIAHHLVGVKKIQQVLAQPGVLEKFINNDKESLQRVKRSFTGLYSLSKEDIDMSVVKEAIESPQNYVMKPQREGGGNNIYNDQVAIALKSMSSEELSSYILMDKIMSKSFKTHVVRDRQLLEIEGLYELGIYSVFISNGDDDIVLNKQAGILLRTKTANSDEVGVAAGFGLLDSPILE", "length": 476 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86B44-1", "protein_name": "Glutathione synthetase", "gene_name": "Gss2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSDANTAVLRNCIRLPLAEDELLEVTAKAKDYAIMHGAAMRSKTAFSPDSLNFAPFVLVPSSFPRKEFEKAVALQPIINRLMHNVAHDEEFITTTLAETIKVDEFTANLFNIYRKVLAHGFTQKTSLGMLRSDLMLESGCPELSPRALRTAAGEDRGQDAGAAVGQIAGANGAAGVGTAAGTGSKEEEHREVQLSRVTKEPERRATGAQSAYCCWKQVEINTIASGFGHLGPASKTIQRFVLSELGHADKLHNMPDNNALAGLCDGMVKAWDIYAKPQAVILFIIEDVSYNICDQRFHEFYIRETYPHIKVLRRTLTEVHREGKLGQSKELLLGSQEVAVIYFRAGYEPGHYHSQADWDARYLMETSLAIKCPSIHYHLAGTKKVQQALAQPAVLERFINDPEEIKAVGKIFTGLYSLDDNEAGNASYEMALRTPERFVLKPQREGGGNNVYGVDIPDALKRMSRVERSAWILMDLIHPPLTKGYMVRPGGDMPPQIVDMVSELGIFGVVIGDAEHIVHNYQAGHMLRTKLSTANEGGVAAGLGALDSPYLIDSDDEDEQK", "length": 562 }, "evidence": [ { "id": "A0A140T850", "url": "https://omabrowser.org/oma/group/A0A140T850/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "glutathione synthase activity", "id": "GO:0004363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004363", "evidence": [ { "database": "UniProtKB", "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ], "pmid": "" }, { "name": "glutathione binding", "id": "GO:0043295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043295", "evidence": [ { "database": "UniProtKB", "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A140T850", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13557", "name": "", "equation": "gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5EAC2-1", "A0A140T850-1" ], "evidence": [ { "id": "13557", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13557" } ] }, { "id": "R-BTA-174394", "name": "GSS:Mg2+ dimer synthesizes GSH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-174393" ], "output_participant_list": [], "enzyme_list": [ "A0A140T850-1" ], "evidence": [ { "id": "R-BTA-174394", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-174394" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-174393", "participant_name": "gGluCys [cytosol]", "crossref": [ { "id": "58173", "database": "ChEBI", "url": "" }, { "id": "ZINC000003870040", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T850", "gene_name": "GSS", "activity": [ { "ec_number": "6.3.2.3", "activity": "gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A140T850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ] }, { "ec_number": "6.3.2.3", "activity": "", "evidence": [ { "id": "A0A140T850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" } ] } ] }, { "uniprot_ac": "Q5EAC2", "gene_name": "GSS", "activity": [ { "ec_number": "6.3.2.3", "activity": "gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+).", "evidence": [ { "id": "Q5EAC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAC2" } ] }, { "ec_number": "6.3.2.3", "activity": "", "evidence": [ { "id": "Q5EAC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAC2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A140T850-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 474, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A140T850-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A140T850" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A140T850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" }, { "id": "PF03199", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutathione synthase substrate-binding", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 302, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "A0A140T850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" }, { "id": "PIRSR001558-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001558-2" } ], "binding_site_uniprot": 144, "amino_acid": "Glu", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 144, "end_pos": 144, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A140T850", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T850" }, { "id": "PIRSR001558-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001558-2" } ], "binding_site_uniprot": 146, "amino_acid": "Asn", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 146, "end_pos": 146, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR001558-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR001558-2" } ], "binding_site_uniprot": 148, "amino_acid": "Val", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 148, "end_pos": 148, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR001558-2", "database": "PIR Site Rule", "url": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"ENSBTAP00000006892.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006892.5" } ] } }, { "isoform_ac": "A0AAA9SUG5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUG5/entry", "sequence": { "sequence": "MELLKPNRSVLGSGPGPGASLCRSGGPLLNGSGTGNLSCEPPRIRGAGTRGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWMLSGLLMVPYPVYTAVQPAGPRVLQCMHRWPSARVRQTWSVLLLLLLFFVPGVVMAVAYGLISRELYLGLRFDGDSDSESQSRVGSQGGLPGPAQANGRCRSETRLAGEDGDGCYVQLPRSRPALEMSALTAPTPGPGSGTRPAQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCTRCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG", "length": 365, "header": "tr|A0AAA9SUG5-1|A0A140T858_BOVIN Computationally mapped isoform of Gastrin/cholecystokinin type B receptor OS=Bos taurus OX=9913 GN=CCKBR PE=3 SV=1 CANONICAL=A0A140T858-1" }, "locus": { "chromosome": "15", "start_pos": 46776143, "end_pos": 46766297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092619.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092619.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090092.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090092.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 434, "start_aa": "Thr", "end_pos": 434, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr434", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:281665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281665", "resource": "KEGG Pathway" }, { "id": "R-BTA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-BTA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-BTA-881907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-881907", "resource": "Reactome", "description": "Gastrin-CREB signalling pathway via PKC and MAPK" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2K5-1", "protein_name": "Gastrin/cholecystokinin type B receptor", "gene_name": "CCKBR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELLKLNRSLPGPGPGAALCRPEGPLLNGSGAGNLSCEPPRIRGAGTRELELAVRITLYAAIFLMSVAGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVVCKAVSYFMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWMLSGLLMVPYPVYTAVQPAGPRVLQCMHRWPSARIRQTWSVLLLLLLFFVPGVVMAVAYGLISRELYLGLRFDGDSDCESQSQVGSQGGLPGGAGQGPAHPNGHCRSETRLAGEDGDGCYVQLPRSRPALEMSALTAPTPGPGSGPRPAQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG", "length": 452 }, "evidence": [ { "id": "A0A140T858", "url": "https://omabrowser.org/oma/group/A0A140T858/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P30553-1", "protein_name": "Gastrin/cholecystokinin type B receptor", "gene_name": "Cckbr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELLKLNRSVQGPGPGSGSSLCRPGVSLLNSSSAGNLSCDPPRIRGTGTRELEMAIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAISYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTMVQPVGPRVLQCMHRWPSARVQQTWSVLLLLLLFFIPGVVIAVAYGLISRELYLGLHFDGENDSETQSRARNQGGLPGGAAPGPVHQNGGCRPVTSVAGEDSDGCCVQLPRSRLEMTTLTTPTPGPVPGPRPNQAKLLAKKRVVRMLLVIVLLFFLCWLPVYSVNTWRAFDGPGAQRALSGAPISFIHLLSYVSACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPQPLPDEDPPTPSIASLSRLSYTTISTLGPG", "length": 452 }, "evidence": [ { "id": "A0A140T858", "url": "https://omabrowser.org/oma/group/A0A140T858/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P32239-1", "protein_name": "Gastrin/cholecystokinin type B receptor", "gene_name": "CCKBR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG", "length": 447 }, "evidence": [ { "id": "A0A140T858", "url": "https://omabrowser.org/oma/group/A0A140T858/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P56481-1", "protein_name": "Gastrin/cholecystokinin type B receptor", "gene_name": "Cckbr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANTWRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG", "length": 453 }, "evidence": [ { "id": "A0A140T858", "url": "https://omabrowser.org/oma/group/A0A140T858/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A140T858", "url": "https://www.uniprot.org/uniprotkb/A0A140T858" } ], "pmid": "" } ] }, { "name": "Biological 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469, "header": "tr|A0AAA9T240-1|A0A140T871_BOVIN Computationally mapped isoform of Glutamate dehydrogenase 1, mitochondrial OS=Bos taurus OX=9913 GN=GLUD1 PE=1 SV=1 CANONICAL=A0A140T871-1" }, "locus": { "chromosome": "28", "start_pos": 41648901, "end_pos": 41610264, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126963.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126963.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090461.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090461.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 412, "start_aa": "Thr", "end_pos": 412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr412", "evidence": 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B, Biointerfaces", "date": "2010-11-01", "authors": "Cai Ling, Xie Yanfang, Li Li, Li Huihui, Yang Xiaodi, Liu Songqin", "evidence": [ { "database": "RefSeq", "id": "NP_872593", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_872593" } ], "reference": [ { "type": "PubMed", "id": "20675102", "url": "https://glygen.org/publication/PubMed/20675102" } ] }, { "title": "Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.", "journal": "Molecular pharmacology", "date": "2016-06", "authors": "Borgnia Mario J, Banerjee Soojay, Merk Alan, Matthies Doreen, Bartesaghi Alberto, Rao Prashant, Pierson Jason, Earl Lesley A, Falconieri Veronica, Subramaniam Sriram, Milne Jacqueline L S", "evidence": [ { "database": "RefSeq", "id": "NP_872593", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_872593" } ], "reference": [ { "type": "PubMed", "id": "27036132", "url": "https://glygen.org/publication/PubMed/27036132" } ] }, { "title": "Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase.", "journal": "Int. 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Sci.", "date": "2022", "authors": "Aleshin Vasily A, Bunik Victoria I, Bruch Eduardo M, Bellinzoni Marco", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "reference": [ { "type": "PubMed", "id": "36232607", "url": "https://glygen.org/publication/PubMed/36232607" } ] } ], "pathway": [ { "id": "bta:281785", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281785", "resource": "KEGG Pathway" }, { "id": "R-BTA-2151201", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2151201", "resource": "Reactome", "description": "Transcriptional activation of mitochondrial biogenesis" }, { "id": "R-BTA-8964539", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8964539", "resource": "Reactome", "description": "Glutamate and glutamine metabolism" }, { "id": "R-BTA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NT61-1", "protein_name": "Glutamate dehydrogenase 1, mitochondrial", "gene_name": "GLUD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYRYLGEQLFARLAGSAVLAGAEPGGPAAAAAGGAAAVWGGGRCPRRHYCEAANKEDDPNFFKMVEGFFDRGASIVEDKLVEGLRTRESMEERRHRVRGILRIIKPCNHVLSVSFPIKRDNGEWEVIEGYRAQHSQHRTPCKGGIRYSLDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGVDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGLFHGIENFINEASYMSILGMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGEFNGSIWNPDGIDPKELEDYKLQHGTIMGFPKAQKLEGSILETDCDILIPAASEKQLTKANAHKVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPVVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGLTFT", "length": 553 }, "evidence": [ { "id": "A0A140T871", "url": "https://omabrowser.org/oma/group/A0A140T871/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4FNG9-1", "protein_name": "Glutamate dehydrogenase", "gene_name": "GLUD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYRCLGEALLGRTRGQPATAPQPGLAPPARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGTILGFPKAKIYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "length": 538 }, "evidence": [ { "id": "A0A140T871", "url": "https://omabrowser.org/oma/group/A0A140T871/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P00367-1", "protein_name": "Glutamate dehydrogenase 1, mitochondrial", "gene_name": "GLUD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "length": 558 }, "evidence": [ { "id": "A0A140T871", "url": "https://omabrowser.org/oma/group/A0A140T871/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07262-1", "protein_name": "NADP-specific glutamate dehydrogenase 1", "gene_name": "GDH1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEPEFQQAYEEVVSSLEDSTLFEQHPEYRKVLPIVSVPERIIQFRVTWENDKGEQEVAQGYRVQYNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNSLTGLDMGGGKGGLCVDLKGRSNNEIRRICYAFMRELSRHIGQDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLNWGGSLIRPEATGYGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGTVVSLSDSKGCIISETGITSEQVADISSAKVNFKSLEQIVNEYSTFSENKVQYIAGARPWTHVQKVDIALPCATQNEVSGEEAKALVAQGVKFIAEGSNMGSTPEAIAVFETARSTATGPSEAVWYGPPKAANLGGVAVSGLEMAQNSQRITWTSERVDQELKRIMINCFNECIDYAKKYTKDGKVLPSLVKGANIASFIKVSDAMFDQGDVF", "length": 454 }, "evidence": [ { "id": "A0A140T871", "url": "https://omabrowser.org/oma/group/A0A140T871/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P10860-1", "protein_name": "Glutamate dehydrogenase 1, mitochondrial", "gene_name": "Glud1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRRLGEVLLLSRAGPAALGSAAADSAALLGWARGQPSAVPQPGLTPVARRHYSEAATDREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRENEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGLGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPVVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "length": 558 }, "evidence": [ { "id": "A0A140T871", "url": "https://omabrowser.org/oma/group/A0A140T871/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P26443-1", "protein_name": "Glutamate dehydrogenase 1, mitochondrial", "gene_name": "Glud1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRRLGEALLLSRAGPAALGSAAADSAALLGWARGQPSAAPQPGLTPVARRHYSEAAADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPVVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT", "length": 558 }, "evidence": [ { "id": "A0A140T871", "url": "https://omabrowser.org/oma/group/A0A140T871/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54385-1", "protein_name": "Glutamate dehydrogenase, mitochondrial", "gene_name": "Gdh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYHLKSLARQGARRQQELATLAKALPTAVMQSSRGYATEHQIPDRLKDVPTAKDPRFFDMVEYFFHRGCQIAEESLVDDMKGKLTRDEKKQKVKGILMLMQPCDHIIEIAFPLRRDAGNYEMITGYRAQHSTHKTPTKGGIRFSLDVSRDEVKALSALMTFKCACVDVPFGGAKAGLKINPKEYSEHELEKITRRFTLELAKKGFIGPGVDVPAPDMGTGEREMSWIADTYAKTIGHLDINAHACVTGKPINQGGIHGRVSATGRGVFHGLENFINEANYMSQIGTTPGWGGKTFIVQGFGNVGLHTTRYLTRAGATCIGVIEHDGTLYNPEGIDPKLLEDYKNEHGTIVGYQNAKPYEGENLMFEKCDIFIPAAVEKVITSENANRIQAKIIAEAANGPTTPAADKILIDRNILVIPDLYINAGGVTVSFFEWLKNLNHVSYGRLTFKYERESNYHLLASVQQSIERIINDESVQESLERRFGRVGGRIPVTPSESFQKRISGASEKDIVHSGLDYTMERSARAIMKTAMKYNLGLDLRTAAYVNSIEKIFTTYRDAGLAF", "length": 562 }, "evidence": [ { "id": "A0A140T871", "url": "https://omabrowser.org/oma/group/A0A140T871/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" }, { "name": "glutamate dehydrogenase (NAD+) activity", "id": "GO:0004352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004352", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" }, { "name": "glutamate dehydrogenase [NAD(P)+] activity", "id": "GO:0004353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004353", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "glutamine metabolic process", "id": "GO:0006541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006541", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" }, { "name": "L-glutamate catabolic process", "id": "GO:0006538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006538", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" }, { "name": "tricarboxylic acid metabolic process", "id": "GO:0072350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072350", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" }, { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "A0A140T871", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11612", "name": "", "equation": "L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T871-1", "P00366-1" ], "evidence": [ { "id": "11612", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11612" } ] }, { "id": "15133", "name": "", "equation": "L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T871-1", "P00366-1" ], "evidence": [ { "id": "15133", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15133" } ] }, { "id": "R-BTA-5688276", "name": "SIRT4 transfers ADPRib to GLUD", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-BTA-70582" ], "output_participant_list": [ "R-BTA-5688244", "R-ALL-5688274" ], "enzyme_list": [ "Q1JQC6-1", "A0A140T871-1" ], "evidence": [ { "id": "R-BTA-5688276", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5688276" } ] }, { "id": "R-BTA-5688289", "name": "SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-5688337" ], "enzyme_list": [ "Q04467-1", "G5E521-1", "A0A140T871-1", "E1BHL1-1" ], "evidence": [ { "id": "R-BTA-5688289", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5688289" } ] }, { "id": "R-BTA-70589", "name": "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T871-1" ], "evidence": [ { "id": "R-BTA-70589", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70589" } ] }, { "id": "R-BTA-70600", "name": "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T871-1" ], "evidence": [ { "id": "R-BTA-70600", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-70600" } ] }, { "id": "R-BTA-9838081", "name": "LONP1 degrades mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "Q2KIE6-1", "P15690-1", "P20000-1", "Q32LG3-1", "P20004-1", "A0AAA9S896-1", "P00829-1", "Q5EAD4-1", "Q2TBR0-1", "F1MTT7-1", "Q148N0-1", "P11181-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q0NXR6-1", "Q29RZ0-1", "F1MXW5-1", "F1N338-1", "G3MWG4-1", "A0A140T871-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "O02691-1", "A0A3Q1LR42-1", "Q3ZCH0-1" ], "evidence": [ { "id": "R-BTA-9838081", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838081" } ] }, { "id": "R-BTA-9838093", "name": "LONP1 binds mitochondrial matrix proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29RK1-1", "Q2KIE6-1", "P15690-1", "P20000-1", "Q32LG3-1", "P20004-1", "A0AAA9S896-1", "P00829-1", "Q5EAD4-1", "Q2TBR0-1", "F1MTT7-1", "Q148N0-1", "P11181-1", "A0A3Q1LS67-1", "G3N0R5-1", "G3MWN1-1", "P11966-1", "P22600-1", "Q0NXR6-1", "Q29RZ0-1", "F1MXW5-1", "F1N338-1", "G3MWG4-1", "A0A140T871-1", "A0A3Q1LS03-1", "A0A3Q1LYU1-1", "O02691-1", "A0A3Q1LR42-1", "Q3ZCH0-1" ], "evidence": [ { "id": "R-BTA-9838093", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9838093" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5688274", "participant_name": "NAM [mitochondrial matrix]", "crossref": [ { "id": "C00153", "database": "COMPOUND", "url": "" }, { "id": "HMDB0001406", "database": "HMDB Metabolite", "url": "" }, { "id": "17154", "database": "ChEBI", "url": "" }, { "id": "ZINC000000005878", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-5688337", "participant_name": "2'-O-acetyl-ADP-ribose [mitochondrial matrix]", "crossref": [ { "id": "83767", "database": "ChEBI", "url": "" }, { "id": "ZINC000096095472", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-BTA-5688244", "participant_name": "phospho-RibC-GLUD1 [mitochondrial matrix]", "crossref": [ { "id": "ENSBTAG00000007540", "database": "ENSEMBL", "url": "" }, { "id": "8AR7", "database": "PDB", "url": "" }, { "id": "ENSBTAT00000009923", "database": "ENSEMBL", "url": "" }, { "id": "NP_872593.2", "database": "RefSeq", "url": "" }, { "id": "8AR8", "database": "PDB", "url": "" }, { "id": "A0A140T871", "database": "UniProt", "url": "" }, { "id": "ENSBTAP00000009923", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-70582", "participant_name": "GLUD1 [mitochondrial matrix]", "crossref": [ { "id": "A0A140T871", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000007540", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000009923", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000009923", "database": "ENSEMBL", "url": "" }, { "id": "8AR8", "database": "PDB", "url": "" }, { "id": "8AR7", "database": "PDB", "url": "" }, { "id": "NP_872593.2", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T871", "gene_name": "GLUD1", "activity": [ { "ec_number": "1.4.1.3", "activity": "L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+).", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] }, { "ec_number": "1.4.1.3", "activity": "", "evidence": [ { "id": "A0A140T871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T871" } ] } ] }, { "uniprot_ac": "A0A3Q1LR42", "gene_name": "NADK2", "activity": [ { "ec_number": "2.7.1.23", "activity": "NAD(+) + ATP = ADP + NADP(+) + H(+).", "evidence": [ { "id": "A0A3Q1LR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR42" } ] }, { "ec_number": "2.7.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1LR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR42" } ] } ] }, { "uniprot_ac": "A0A3Q1LS03", "gene_name": "", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A3Q1LS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS03" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A3Q1LS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS03" } ] } ] }, { "uniprot_ac": "A0A3Q1LS67", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/F1MXW5" } ] }, { "ec_number": "2.3.1.41", "activity": "", "evidence": [ { "id": "F1MXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXW5" } ] } ] }, { "uniprot_ac": "F1N338", "gene_name": "HADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "F1N338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N338" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "F1N338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N338" } ] } ] }, { "uniprot_ac": "G3MWG4", "gene_name": "IARS2", "activity": [ { "ec_number": "6.1.1.5", "activity": "tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate.", "evidence": [ { "id": "G3MWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWG4" } ] }, { "ec_number": "6.1.1.5", "activity": "", 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2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "Q148N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148N0" } ] }, { "ec_number": "1.2.4.2", "activity": "", "evidence": [ { "id": "Q148N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148N0" } ] } ] }, { "uniprot_ac": "Q1JQC6", "gene_name": "SIRT4", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "Q1JQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQC6" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q1JQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQC6" } ] }, { "ec_number": "2.3.1.286", "activity": "N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].", "evidence": [ { "id": "Q1JQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQC6" } ] } ] }, { "uniprot_ac": "Q29RK1", "gene_name": "CS", "activity": [ { "ec_number": "2.3.3.1", "activity": "oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+).", "evidence": [ { "id": "Q29RK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RK1" } ] }, { "ec_number": "2.3.3.1", "activity": "", "evidence": [ { "id": "Q29RK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RK1" } ] } ] }, { "uniprot_ac": "Q29RZ0", "gene_name": "ACAT1", "activity": [ { "ec_number": "2.3.1.9", "activity": "2 acetyl-CoA = acetoacetyl-CoA + CoA.", "evidence": [ { "id": "Q29RZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RZ0" } ] }, { "ec_number": "2.3.1.9", "activity": "", "evidence": [ { "id": "Q29RZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RZ0" } ] } ] }, { "uniprot_ac": "Q2KIE6", "gene_name": "HMGCS2", "activity": [ { "ec_number": "2.3.3.10", "activity": "acetoacetyl-CoA + acetyl-CoA + H2O = 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endothelial nitric oxide synthase.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2005-06-21", "authors": "Chalupsky Karel, Cai Hua", "evidence": [ { "database": "RefSeq", "id": "NP_001071351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071351" } ], "reference": [ { "type": "PubMed", "id": "15941833", "url": "https://glygen.org/publication/PubMed/15941833" } ] }, { "title": "MiR-139 promotes differentiation of bovine skeletal muscle-derived satellite cells by regulating DHFR gene expression.", "journal": "Journal of cellular physiology", "date": "2018-01", "authors": "Zhou Shuang, Li Shuang, Zhang Weiwei, Tong Huili, Li Shufeng, Yan Yunqin", "evidence": [ { "database": "RefSeq", "id": "NP_001071351", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071351" } ], "reference": [ { "type": "PubMed", "id": "30078180", "url": "https://glygen.org/publication/PubMed/30078180" } ] } ], "pathway": [ { "id": "bta:508809", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508809", "resource": "KEGG Pathway" }, { "id": "R-BTA-196757", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196757", "resource": "Reactome", "description": "Metabolism of folate and pterines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABU6-1", "protein_name": "Dihydrofolate reductase", "gene_name": "DHFR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEYKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPQGAHFLAKSLDDALKLTEQPELKNKVDMVWIVGGSSVYKEAMNKPGHIRLFVTRIMKEFESDTFFPEIDLEKYKLLSECSGVPSDVQEEKGIKYKFEVYEKNN", "length": 187 }, "evidence": [ { "id": "A0A140T872", "url": "https://omabrowser.org/oma/group/A0A140T872/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P00374-1", "protein_name": "Dihydrofolate reductase", "gene_name": "DHFR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND", "length": 187 }, "evidence": [ { "id": "A0A140T872", "url": "https://omabrowser.org/oma/group/A0A140T872/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P00375-1", "protein_name": "Dihydrofolate reductase", "gene_name": "Dhfr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPRGAHFLAKSLDDALRLIEQPELASKVDMVWIVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLGKYKLLPEYPGVLSEVQEEKGIKYKFEVYEKKD", "length": 187 }, "evidence": [ { "id": "A0A140T872", "url": "https://omabrowser.org/oma/group/A0A140T872/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q920D2-1", "protein_name": "Dihydrofolate 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"https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "folate reductase activity", "id": "GO:0033560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033560", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "tetrahydrofolate biosynthetic process", "id": "GO:0046654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046654", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "folic acid metabolic process", "id": "GO:0046655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046655", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "response to methotrexate", "id": "GO:0031427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031427", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "dihydrofolate metabolic process", "id": "GO:0046452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046452", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "tetrahydrobiopterin biosynthetic process", "id": "GO:0006729", "url": 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"" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A140T872", "url": "https://www.uniprot.org/uniprotkb/A0A140T872" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15009", "name": "", "equation": "(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T872-1", "P00376-1" ], "evidence": [ { "id": "15009", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15009" } ] }, { "id": "R-BTA-197963", "name": "DHFR2 reduces FOLA to DHF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T872-1" ], "evidence": [ { "id": "R-BTA-197963", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-197963" } ] }, { "id": "R-BTA-197972", "name": "DHF is reduced to tetrahydrofolate (THF)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-73604" ], "output_participant_list": [], "enzyme_list": [ "A0A140T872-1" ], "evidence": [ { "id": "R-BTA-197972", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-197972" } ] }, { "id": "R-BTA-9709098", "name": "DHFR dimer reduces FOLA to DHF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T872-1" ], "evidence": [ { "id": "R-BTA-9709098", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9709098" } ] }, { "id": "R-BTA-9709109", "name": "DHFR dimer binds DHFR inhibitors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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"MNGRADFREPNTEVPRPIPHIGADYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLIFACIMGYFAGKLSYVKTCQEKFKNLENSPLGEALRSGQARRSSPTGHYSQRSKYDSNVSGHSSFGTSPAADNLEKEMLPHYEPIPFSASLNESTPTGITDHIAQGPDPNTEESPKRKNITYEELRNKNRESYEVTLTHKTDPSVRPMQERMPKKEGKQIWRYLG", "length": 244, "header": "tr|A0A140T883-1|A0A140T883_BOVIN Isoform 1 of OCIA domain-containing protein 1 OS=Bos taurus OX=9913 GN=OCIAD1 PE=3 SV=2 CANONICAL=A0A140T883-1" }, "isoforms": [ { "isoform_ac": "A0A140T883-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T883/entry", "sequence": { "sequence": "MNGRADFREPNTEVPRPIPHIGADYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLIFACIMGYFAGKLSYVKTCQEKFKNLENSPLGEALRSGQARRSSPTGHYSQRSKYDSNVSGHSSFGTSPAADNLEKEMLPHYEPIPFSASLNESTPTGITDHIAQGPDPNTEESPKRKNITYEELRNKNRESYEVTLTHKTDPSVRPMQERMPKKEGKQIWRYLG", "length": 244, "header": "tr|A0A140T883-1|A0A140T883_BOVIN Isoform 1 of OCIA domain-containing protein 1 OS=Bos taurus OX=9913 GN=OCIAD1 PE=3 SV=2 CANONICAL=A0A140T883-1" }, "locus": { 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"database": "Ensembl Peptide", "id": "ENSBTAP00000059218.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059218.2" } ] } }, { "isoform_ac": "A0ABI0NJ64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ64/entry", "sequence": { "sequence": "MNGRADFREPNTEVPRPIPHIGADYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLIFACIMGYFAGKLSYVKTCQEKFKNLENSPLGEALRSGQARRSSPTGHYSQRSKYDSNVSGHSSFGTSPAADNLEKEMLPHYEPIPFSASLNESTPTGITDHIAQGRNFS", "length": 189, "header": "tr|A0ABI0NJ64-1|A0ABI0NJ64_BOVIN Computationally mapped isoform of OCIA domain-containing protein 1 OS=Bos taurus OX=9913 GN=OCIAD1 PE=3 SV=1 CANONICAL=A0A140T883-1" }, "locus": { "chromosome": "6", "start_pos": 67512039, "end_pos": 67497968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144463.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144463.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104411.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104411.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q2S1-1", "protein_name": "OCIA domain-containing protein 1", "gene_name": "LOC553528", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQTPADSERPGHAGNLGPLRMDYTPTEEERRVFRECNQESFWYSSLPISVVSMAVTQLLISRGALSASGRFGSLPKLAFAGFCGYVGGKMSYMKKCIEKFKNLENSPLGEALRQQQRHQHQKFTQDQSELSDPNKADFEPAFQLEDQKDQSFSYDRDFTYSDPMMTSSTQNTASSNNPSHIEEDVQDRRVLYGDLRSKHRENYEVTMTKKSEMLLKPSERSSVTRGKKNIYGDNWEE", "length": 239 }, "evidence": [ { "id": "A0A140T883", "url": "https://omabrowser.org/oma/group/A0A140T883/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YX92-1", "protein_name": "OCIA domain-containing protein 1", "gene_name": "OCIAD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAGQGPGGRELGDPPENTVPKHYVPTEEERRLLKECAEESARYRAFPLAAASMLATSFLIKKGILRDSSRFGSFTKVAFAGMCGYLAGKISYLPICSEKFKKLKDSPIGDVLRQAQRHSSHSYSSRKSEFSDMPFQSFTESSPKAGFSPSSGYSDDYSSTDRALSSYEPVPFSASLNESSPTGITDYNVQETPPIPEESRKKKSVTYEELRNKHRETYEVMSPLKAETPGKFPQERPVKEVKVNKYGDTWDE", "length": 253 }, "evidence": [ { "id": "A0A140T883", "url": "https://omabrowser.org/oma/group/A0A140T883/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4FAD4-1", "protein_name": "OCIA domain-containing protein 1", "gene_name": "OCIAD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRAEFREPNAEVPRPIPHIGADYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPRYGSIPKLIFACIMGYFAGKLSYVKTCQEKFKNLENSPLGEALRSGQARRSSPTGHYSQKSRYDSNVSGHSSFATSPAADNIEKEMLPHYEPIPFSASMNESAPTGITDHIAQGPDPNIEESPKRKNVTYEELRNKNRESYEVTLTHKTDPSVRPMQERMPKKEVKVNKYGDTWDE", "length": 247 }, "evidence": [ { "id": "A0A140T883", "url": "https://omabrowser.org/oma/group/A0A140T883/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IEB4-1", "protein_name": "OCIA domain-containing protein 1", "gene_name": "Ociad1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGRADFREPNAEVPRPIPHIGADYIPTEEERRVFRECNEESFWFRSVPLAATSMLITQGLISKGILSSHPKFGSIPKLIFACIMGYFAGKLSYVKTCQEKFKNLENSPLGEALRSGQARRSSPPGHYAQKSKYDSNVSGQSSFVTSPAADDIDKETLPRYEPIPFSASMNESTPTGITDHIAQGPDPNFEESPKRKSITYEELRSKNRESYEVTLTHKTDPSVRPMQERVPQKEVKVNKYGDTWDE", "length": 247 }, "evidence": [ { "id": "A0A140T883", "url": "https://omabrowser.org/oma/group/A0A140T883/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XIG4-1", "protein_name": "OCIA domain-containing protein 1", "gene_name": "Ociad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGRADFREPNAQVSRPIPDIGGGYIPTEEEWRLFAECHEECFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLIFACIVGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGELRRSLPPGHYTQKPKYDSNVSGQSSFGTSPAADNIEKETLPRYEPIPFSASMNESTPTGITDHIAQGPDPNLEDSPKRKSVTYEELRNKNRESYGVTLSHKTDPSVRPMQERGPQKEVKVNKYGDTWDE", "length": 247 }, "evidence": [ { "id": "A0A140T883", "url": "https://omabrowser.org/oma/group/A0A140T883/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CRD0-1", "protein_name": "OCIA domain-containing protein 1", "gene_name": "Ociad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGRADFREPNAQVSRPIPDIGGGYIPTEEEWRLFAECHEECFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLLFACIVGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGELRRSSPPGHYTQKPKFDSNVSGQSSFGTSPAADNIEKEALPRYEPIPFSASMNESTPTGITDHIAQGPEPNLEESPKRKGVTYEELRSKNRESYGVTLPHKTDPSVRPMQERVPKKEVKVNKYGDTWDE", "length": 247 }, "evidence": [ { "id": "A0A140T883", "url": "https://omabrowser.org/oma/group/A0A140T883/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX40-1", "protein_name": "OCIA domain-containing protein 1", "gene_name": "OCIAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGRADFREPNAEVPRPIPHIGPDYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLILACIMGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGQARRSSPPGHYYQKSKYDSSVSGQSSFVTSPAADNIEMLPHYEPIPFSSSMNESAPTGITDHIVQGPDPNLEESPKRKNITYEELRNKNRESYEVSLTQKTDPSVRPMHERVPKKEVKVNKYGDTWDE", "length": 245 }, "evidence": [ { "id": "A0A140T883", "url": "https://omabrowser.org/oma/group/A0A140T883/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A140T883", "url": "https://www.uniprot.org/uniprotkb/A0A140T883" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of stem cell differentiation", "id": "GO:2000736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000736", "evidence": [ { "database": "UniProtKB", "id": "A0A140T883", "url": "https://www.uniprot.org/uniprotkb/A0A140T883" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A140T883", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T883" }, { "id": "PF07051", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07051" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OCIA", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 109, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 198, "end_pos": 200 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A140T885-1", "uniprot_ac": "A0A140T885", "uniprot_id": "A0A140T885_BOVIN", "mass": { "chemical_mass": 73417.0, "monoisotopic_mass": 73417.0 }, "refseq": { "ac": "NP_851349", "name": "secretogranin-1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" }, "gene_names": [ { "name": "CHGB", "type": "recommended", "evidence": [ { "id": "A0A140T885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T885" } ] }, { "name": "CHGB", "type": "synonym", "evidence": [ { "id": "NP_851349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ] } ], "protein_names": [ { "name": "Secretogranin-1", "type": "recommended", "evidence": [ { "id": "A0A140T885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T885/entry#names_and_taxonomy" } ] }, { "name": "Chromogranin-B", "type": "synonym", "evidence": [ { "id": "A0A140T885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T885/entry#names_and_taxonomy" } ] }, { "name": "cgB", "type": "synonym", "evidence": [ { "id": "NP_851349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ] }, { "name": "chromogranin B (secretogranin 1)", "type": "synonym", "evidence": [ { "id": "NP_851349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ] }, { "name": "secretogranin I", "type": "synonym", "evidence": [ { "id": "NP_851349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ] }, { "name": "secretogranin-1 precursor", "type": "synonym", "evidence": [ { "id": "NP_851349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ] }, { "name": "secretogranin-1", "type": "synonym", "evidence": [ { "id": "NP_851349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ] }, { "name": "sgI", "type": "synonym", "evidence": [ { "id": "NP_851349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ] } ], "function": [ { "annotation": "CGB may play an important modulatory role in the control of Ca2+ release from the endoplasmic reticulum", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" }, { "database": "PubMed", "id": "14506248", "url": "https://glygen.org/publication/PubMed/14506248" } ] }, { "annotation": "Chromogranin B was found to co-localize with secretogranin II and IP3 receptors in the nucleus, more specifically, in the IP3-sensitive nucleoplasmic Ca2+ store vesicles.", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" }, { "database": "PubMed", "id": "18020452", "url": "https://glygen.org/publication/PubMed/18020452" } ] }, { "annotation": "Colocalization of all three inositol 1,4,5-trisphosphate receptor (IP(3)R)isoforms with chromogranin B to the extent that the majority of each IP(3)R isoform-labeling gold particles found in the nucleoplasm", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" }, { "database": "PubMed", "id": "15966749", "url": "https://glygen.org/publication/PubMed/15966749" } ] }, { "annotation": "Determination of the subcellular distribution of chromogranins A and B in chromaffin cells; results suggest that chromogranins are at the center of intracellular Ca(2+) homeostasis in secretory cells", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" }, { "database": "PubMed", "id": "16140299", "url": "https://glygen.org/publication/PubMed/16140299" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T885", "url": "https://www.uniprot.org/uniprotkb/A0A140T885" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHGB", "url": "https://www.uniprot.org/uniprotkb/A0A140T885", "locus": { "chromosome": "13", "start_pos": 48084157, "end_pos": 48069202, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011782", "url": "https://www.ensembl.org/id/ENSBTAG00000011782" } ] } } ], "crossref": [ { "id": "A0A140T885", "url": "https://alphafold.ebi.ac.uk/entry/A0A140T885", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011782", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011782", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "281071", "url": "https://www.ncbi.nlm.nih.gov/gene/281071", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281071", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPGHKHQ", "url": "https://omabrowser.org/oma/group/RPGHKHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T885", "url": "https://www.orthodb.org/?gene=A0A140T885", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10583:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10583:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A140T885", "url": "https://www.uniprot.org/uniprotkb/A0A140T885", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T885-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T885-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPAALLGLLGATVVAAVSSMPVDIRNHNEEVVTHCIIEVLSNALLKSSAPPITPECRQVLKKNGKELKDEEKSENENTRFEVRLLRDPADTSEAPGLSSREDSGEGDAQVPTVADTESGGHSRERAGEPPGSQVAKEAKTRYSKSEGQNREEEMVKYQKRERGEVGSEERLSEGPGKAQMAFLNQRNQTPAKKEELVSRYDTQSARGLEKSHSRERSSQESGEETKSQENWPQELQRHPEGQEAPGESEEDASPEVDKRRSRPRHHHGRSRPDRSSQEGNPPLEEESHVGTGNSDEEKARHPAHFRALEEGAEYGEEVRRHSAAQAPGDLQGARFGGRGRGEHQALRRPSEESLEQENKRHGLSPDLNMAQGYSEESEEERGPARGPSYRARGGEAAAYSTLGQTDEKRFLGETHHRVQESQRDKARRRLPGELRNYLDYGEEKGEEAARGKWQPQGDPRDADENREEARLRGKQYAPHHITEKRLGELLNPFYDPSQWKSSRFERKDPMDDSFLEGEEENGLTLNEKNFFPEYNYDWWEKKPFEEDVNWGYEKRNPVPKLDLKRQYDRVAELDQLLHYRKKSAEFPDFYDSEEQVSPQHTAENEEEKAGQGVLTEEEEKELENLAAMDLELQKIAEKFSGTRRG", "length": 646, "header": "tr|A0A140T885-1|A0A140T885_BOVIN Isoform 1 of Secretogranin-1 OS=Bos taurus OX=9913 GN=CHGB PE=3 SV=1 CANONICAL=A0A140T885-1" }, "isoforms": [ { "isoform_ac": "A0A140T885-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T885/entry", "sequence": { "sequence": "MQPAALLGLLGATVVAAVSSMPVDIRNHNEEVVTHCIIEVLSNALLKSSAPPITPECRQVLKKNGKELKDEEKSENENTRFEVRLLRDPADTSEAPGLSSREDSGEGDAQVPTVADTESGGHSRERAGEPPGSQVAKEAKTRYSKSEGQNREEEMVKYQKRERGEVGSEERLSEGPGKAQMAFLNQRNQTPAKKEELVSRYDTQSARGLEKSHSRERSSQESGEETKSQENWPQELQRHPEGQEAPGESEEDASPEVDKRRSRPRHHHGRSRPDRSSQEGNPPLEEESHVGTGNSDEEKARHPAHFRALEEGAEYGEEVRRHSAAQAPGDLQGARFGGRGRGEHQALRRPSEESLEQENKRHGLSPDLNMAQGYSEESEEERGPARGPSYRARGGEAAAYSTLGQTDEKRFLGETHHRVQESQRDKARRRLPGELRNYLDYGEEKGEEAARGKWQPQGDPRDADENREEARLRGKQYAPHHITEKRLGELLNPFYDPSQWKSSRFERKDPMDDSFLEGEEENGLTLNEKNFFPEYNYDWWEKKPFEEDVNWGYEKRNPVPKLDLKRQYDRVAELDQLLHYRKKSAEFPDFYDSEEQVSPQHTAENEEEKAGQGVLTEEEEKELENLAAMDLELQKIAEKFSGTRRG", "length": 646, "header": "tr|A0A140T885-1|A0A140T885_BOVIN Isoform 1 of Secretogranin-1 OS=Bos taurus OX=9913 GN=CHGB PE=3 SV=1 CANONICAL=A0A140T885-1" }, "locus": { "chromosome": "13", "start_pos": 48083772, "end_pos": 48069312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015645.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015645.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015645.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015645.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel.", "journal": "The Journal of biological chemistry", "date": "2003-12-12", "authors": "Thrower Edwin C, Choe Chi Un, So Seung Ho, Jeon Soung Hoo, Ehrlich Barbara E, Yoo Seung Hyun", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ], "reference": [ { "type": "PubMed", "id": "14506248", "url": "https://glygen.org/publication/PubMed/14506248" } ] }, { "title": "Presence of a nucleoplasmic complex composed of the inositol 1,4,5-trisphosphate receptor/Ca2+ channel, chromogranin B, and phospholipids.", "journal": "Biochemistry", "date": "2005-06-28", "authors": "Yoo Seung Hyun, Nam Seong Won, Huh Seong Kwon, Park Seon Young, Huh Yang Hoon", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ], "reference": [ { "type": "PubMed", "id": "15966749", "url": "https://glygen.org/publication/PubMed/15966749" } ] }, { "title": "Subcellular distribution of chromogranins A and B in bovine adrenal chromaffin cells.", "journal": "FEBS letters", "date": "2005-09-26", "authors": "Huh Yang Hoon, Bahk Sook Jin, Ghee Jung Yeon, Yoo Seung Hyun", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ], "reference": [ { "type": "PubMed", "id": "16140299", "url": "https://glygen.org/publication/PubMed/16140299" } ] }, { "title": "Presence of secretogranin II and high-capacity, low-affinity Ca2+ storage role in nucleoplasmic Ca2+ store vesicles.", "journal": "Biochemistry", "date": "2007-12-18", "authors": "Yoo Seung Hyun, Chu Sei Yoon, Kim Ki Deok, Huh Yang Hoon", "evidence": [ { "database": "RefSeq", "id": "NP_851349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_851349" } ], "reference": [ { "type": "PubMed", "id": "18020452", "url": "https://glygen.org/publication/PubMed/18020452" } ] } ], "pathway": [ { "id": "bta:281071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281071", "resource": "KEGG Pathway" }, { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQZ7-1", "protein_name": "Secretogranin-1", "gene_name": "CHGB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPAVLLGFLGATVVAAVSSMPVDNRNHNEEMVAHCIIEVLSNALSKSNAPPITPECRQVLKKGGKEVKDEEKGANENTRFEVRLLRDPADTSETQRPSGGREGAEAPSEDTQGPPGADVEGGGHSREGAGKPRGGPYSSDNQGQGGKTRHSEKSEGQDREEEEGEKYQKRERGEEGSEERHLQEPGETQTAFLNQGNRATAKKKEEFESRYDAHSAGGPAKTHSRERSSQESGEETGSQDAAPGEPESPPEGQEAPEESQEDASLEVDKRRWRPRHHHGRSRPDRAPQEGSPPPEERGHPREESEESVLGLASPGGQRTRHPTHYPASEEEAEHGEEVRSSSSVQAPGDLVGARYGGRGGAEHRAARRPGEESPEQDRRVASSELRNKGPGHSEESEEERGDEGQRHHRAWAGGPRADAPPDPAEEEQFWGEAHRPVPESQVDEARRHPQAKLRNYLNRGEENGEEGAPGRWQQPEDLQGPGEHAAEARLPGKPYAAHRIPEKKRLGELLNPYYVPPQWESSHFERKDNVGDNFLEGEDANGVTLNEKTFFPEYSYDWWEKKPFEEDVNWGYEERNLAPKLDLKRQYDRVAELDQLLHYRKKSAEFPDFYDSGEHLSPRHAAESEKERAGQGVLTEEEEKELENLAAMDLELQKIAEKFSGNRRG", "length": 666 }, "evidence": [ { "id": "A0A140T885", "url": "https://omabrowser.org/oma/group/A0A140T885/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2B7T7-1", "protein_name": "Secretogranin-1 isoform X1", "gene_name": "chgb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFAAFLCVFVFLAADGGSIPVEQDSRREGLLTKCLVEILSKELYKTDDTPLHPECRNILSQGSDHSKDVKNTKEPTQEELKKPREESKVKDEELIDHLHKAADKREELGDERSQEEFPSFVKRTKDRREEMDDERSQEEFPSFMKRGIKGKREGMDDERSQEEFPSFMKRRLKEKREGMDDDRSQEEFPSFMKRRLKEKREGMDDDRSQEEFPSFMKRRLKEKREGMDDERSQEEFPSFYKRFNMHKREDSDDRSQEEFPQKRFFSMIYKRDNPDEERSQEEFPFYEYKRSHLLTSREKRNDLDYDRSQEAFPSYMIKRTYGDGDEEDEGIEKRIWKPTHRYHHKKKHHKRSENGDIEEPDYDRSQEDFPSYVNKRNYMNGEEMDEESEEREKRIWKPTHRYHHKKKHHKRSENGDIEDPDYDRSQEDFPSYNKRTYGDGDEMDEESEEIEKRNWKPTHRYHHKKKHHKRSENGDIEEPDYDRSQEDFPSKRSQGHYKQTEDLANAQPEESEEQDEDIAKRYWKPTHRYHHKKHYRNKRGDSIELEDESEASQEAEEELNKGQLSSAEAALRYLTNKKKELEERLLNKGDVYEKRSPWIDRGYYRPAWYKRSQKAGESMDQQPYHTLEELAKTLRYKRGLISQEESPEEEISAPQQEQLKELEELASVDQQMTETT", "length": 677 }, "evidence": [ { "id": "A0A140T885", "url": "https://omabrowser.org/oma/group/A0A140T885/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Z2E6-1", "protein_name": "Secretogranin-1", "gene_name": "CHGB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATACCSRNAKSWLEAVIEHLVRRQGQPRGAQVHAMFLSDQKSWSQDPPLPRPRLRAGSGGKGILLKIPAYLRPFKGVSTVPVEKDHMEEMITQCIVEVLSNALSKPNAPPINPECKEILKKGGKTDRERSEDKQLEVRHLKEPSEFENPHSESVEREQSQAEDDSKKRMKGSDEEKLHPGEGNSKEDEEGHHVPVHEEKLHTEEKKHYQEIRREENSYHSEEESRESKQSDGEDDHAVLNRKSHSAGMSTEEGAEENDQRPMDQWHSEEGMQSPHKRIHEGEEGEAEEERSEKYHLTESKGRDFSRHEEREESDESEELKEEKKSYKPKRYHGKHRIGDSSEENRGHGGEKEELAEESNAEESHLWDKRNNHQKHHHEESEQQHEEKSGYRGRHGSEGTEEKRYAGQGNVEYRERWQQSEEKSQEENKRHHHSEESNEKWREERSHHSEGRAYRGDESEEELDRYHSDSSKEKKHHAGGRYRLWDDEGEGTQKVYTREHKGQARTHYNTEDSVEQQHYPGGSDEEEEEVEKKHYSSDQIENEEENMEQGGYEEKEEYRSHLPSENEKRTTASYSPVYPLLWWKSQHFEKRNSAGERLPESKEEGRPTLSEKSPFPEYSDYDWWDKKQLLSALNRGRSEKRNLSKRNRNDMKRQYDKMDQLAQLLNYRKKSAEFLELYNSGEDMKKRHVIRNDKGTLNQRSLTEEEAKELENLAAMDLELQKIAETFNNNRRG", "length": 733 }, "evidence": [ { "id": "A0A140T885", "url": "https://omabrowser.org/oma/group/A0A140T885/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O35314-1", "protein_name": "Secretogranin-1", "gene_name": "Chgb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRAMLLGLLGAAALAAVISAPVDNRDHNEEMVTRCIIEVLSNALSKSSAPTITPECRQVLRKSGKEVKGEEKGENENSKFEVRLLRDPSDASVGRWASSREETGAPVEDSPGQAKVDNEEWTGGGGHSREAVDDQESLHPSNQQVSKEAKIRHSEERGGKEEEEEEGKIYPKGEHRGDAGEEKKHTEESGEKHNAFSNKRSEASAKKKEESVARAEAHFVELEKTHSREQSSQESGEETRRQEKPQELPDQDQSEEESEEGEEGEEGATSEVTKRRPRHHHWRSQSNKPSYEGRRPLSEERKHAAGESKDANVATANLGEKRGHHLAHYRASEEEPDYGEELRSYPGFQAPQGLQYQGRGSEEVRAPSPRSEESQEKEYKRNHPDSELESTANRHSEETEEERSYEGAKGRQHRGRGREPGAYPALDSRQEKRLLDEGHDPVHESPVDTAKRYPQSKWQEQEKNYLNYDEEGDQGRWWQQEEQLEPEESREEVSFPDRQYAPYPTTEKRKRLGALFNPYFDPLQWKNSDFEKKGNPDDSFLDDDGEDGNGVTMTEKNFFPEYNYDWWEKRPFSEDVNWGYEKRSFARAPHLDLKRQYDDGVAELDQLLHYRKKAAEFPDFYDSEEQMGPHQEAEDEKDRADQRVLTEEEKKELENLAAMDLELQKIAEKFSQRG", "length": 675 }, "evidence": [ { "id": "A0A140T885", "url": "https://omabrowser.org/oma/group/A0A140T885/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05060-1", "protein_name": "Secretogranin-1", "gene_name": "CHGB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPTLLLSLLGAVGLAAVNSMPVDNRNHNEGMVTRCIIEVLSNALSKSSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESGEETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEKFSQRG", "length": 677 }, "evidence": [ { "id": "A0A140T885", "url": "https://omabrowser.org/oma/group/A0A140T885/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16014-1", "protein_name": "Secretogranin-1", "gene_name": "Chgb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPAMLLGLLGAAALAAVSSAPVDNRDHNEEMVTRCIIEVLSNALSKSSVPTITPECRQVLKKSGKEVKGEEKGENQNSKFEVRLLRDPADASGTRWASSREDAGAPVEDSQGQTKVGNEKWTEGGGHSREGVDDQESLRPSNQQASKEAKIYHSEERVGKEREKEEGKIYPMGEHREDAGEEKKHIEDSGEKPNTFSNKRSEASAKKKDESVARADAHSMELEEKTHSREQSSQESGEETRRQEKPQELTDQDQSQEESQEGEEGEEGEEGEEGEEDSASEVTKRRPRHHHGRSGSNKSSYEGHPLSEERRPSPKESKEADVATVRLGEKRSHHLAHYRASEEEPEYGEESRSYRGLQYRGRGSEEDRAPRPRSEESQEREYKRNHPDSELESTANRHGEETEEERSYEGANGRQHRGRGREPGAHSALDTREEKRLLDEGHYPVRESPIDTAKRYPQSKWQEQEKNYLNYGEEGDQGRWWQQEEQLGPEESREEVRFPDRQYEPYPITEKRKRLGALFNPYFDPLQWKNSDFEKRGNPDDSFLEDEGEDRNGVTLTEKNSFPEYNYDWWERRPFSEDVNWGYEKRSFARAPQLDLKRQYDGVAELDQLLHYRKKADEFPDFYDSEEQMGPHQEANDEKARADQRVLTAEEKKELENLAAMDLELQKIAEKFSQRG", "length": 677 }, "evidence": [ { "id": "A0A140T885", "url": "https://omabrowser.org/oma/group/A0A140T885/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A140T885", "url": "https://www.uniprot.org/uniprotkb/A0A140T885" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A140T885", "url": "https://www.uniprot.org/uniprotkb/A0A140T885" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A140T885-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 646, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A140T885-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A140T885" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A140T888-1", "uniprot_ac": "A0A140T888", "uniprot_id": "A0A140T888_BOVIN", "mass": { "chemical_mass": 235924.0, "monoisotopic_mass": 235924.0 }, "refseq": {}, "gene_names": [ { "name": "PI4KA", "type": "recommended", "evidence": [ { "id": "A0A140T888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol 4-kinase alpha", "type": "recommended", "evidence": [ { "id": "A0A140T888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T888/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.67", "type": "synonym", "evidence": [ { "id": "A0A140T888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T888/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate.", "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888#function" }, { "database": "UniProtKB", "id": "ARBA00056014", "url": "https://www.uniprot.org/uniprotkb/ARBA00056014#function" }, { "database": "UniProtKB", "id": "A0A3Q1MNL7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNL7#function" }, { "database": "UniProtKB", "id": "A0AAA9S9D7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9D7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PI4KA", "url": "https://www.uniprot.org/uniprotkb/A0A140T888", "locus": { "chromosome": "17", "start_pos": 72208855, "end_pos": 72269169, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013971", "url": "https://www.ensembl.org/id/ENSBTAG00000013971" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013971", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013971", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A140T888", "url": "https://www.orthodb.org/?gene=A0A140T888", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M2C3", "url": "https://www.orthodb.org/?gene=A0A3Q1M2C3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MNL7", "url": "https://www.orthodb.org/?gene=A0A3Q1MNL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10048:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10048:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19274", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19274", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1483248", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483248", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1660514", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660514", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T888-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T888-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2C3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNL7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9D7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9D7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9D7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAAAAARGGGGGGGGGSFGSGAGGGASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDSVVPYLLRLLKGLPKVYWVEESTARKGRGTLPVAESFSFCLVTLLSDVAYRDPSLRGEILEALLQVLHVLLGMCQALEIQEKEYLCKHAVPCLLGIVRAFGRHSSSEDSILSRLFPRAPAHSPRVPEELEGVRRRSFNDFRSILPSSLLTVCQEGSLKRKASSASSVAQVSPERGAPPPSPPGGSAFHCLEASYSPNGSTSESDYYFSAVSSSFSVSPLFNGVTYKEFSIPLEMLRELLNLASFPLQVKKIVEEPVLKSLDAVVTGVIEASPSADLCYGAFSDPLYVAVLRMLRDTLYYMRDLPTSFVKEVHDFVLEQFNSSQGELQKILHDADRAHSELSPLKLRCQASAACVDLMVWAVKDEQGAENLCVKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVVPSPVLVKLYKCHSQYHTVAGNDIKISVTNEHAESTLNVASGKKSQPSMYEQLRDIAIDNVCRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEPKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIVNLLDPAPEVSALIGKLDFAMSTYLLSVYRLEYMRVLRSSDPARFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVSFNHVHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDVPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLSKHQNWVSGLSQHTGLAMATESVLHYAGYNKQSTSLGATQLTERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSDATGHTSDLNKMMVQELKAALGAGDAQQYTQAMFKLTAMLISSRDCDPQLLHHLCWGPLQMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWQMTVEQKFGLFSAEMKEADPLAASEASQPKPCAPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFCSLLQRSLSLSIGGTAGSMNRHVAAIGPRFKLLTLGLSLLHADVLPNATIRNVLREKIYSTAFDYFSCPPRFPTQGEKRLREDISVMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDIAVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGESSVANWRSKYISLSEKQWKDNVNLAWSISPHLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPADPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASQSQLLAHQFIWNMKTNIYVDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDPEEEGSMQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHLIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFILKVIQNCFLSNRSRTYDMIQYYQNDIPY", "length": 2109, "header": "tr|A0A140T888-1|A0A140T888_BOVIN Isoform 1 of Phosphatidylinositol 4-kinase alpha OS=Bos taurus OX=9913 GN=PI4KA PE=3 SV=3 CANONICAL=A0A140T888-1" }, "isoforms": [ { "isoform_ac": "A0A140T888-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T888/entry", "sequence": { "sequence": "MMAAAAARGGGGGGGGGSFGSGAGGGASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDSVVPYLLRLLKGLPKVYWVEESTARKGRGTLPVAESFSFCLVTLLSDVAYRDPSLRGEILEALLQVLHVLLGMCQALEIQEKEYLCKHAVPCLLGIVRAFGRHSSSEDSILSRLFPRAPAHSPRVPEELEGVRRRSFNDFRSILPSSLLTVCQEGSLKRKASSASSVAQVSPERGAPPPSPPGGSAFHCLEASYSPNGSTSESDYYFSAVSSSFSVSPLFNGVTYKEFSIPLEMLRELLNLASFPLQVKKIVEEPVLKSLDAVVTGVIEASPSADLCYGAFSDPLYVAVLRMLRDTLYYMRDLPTSFVKEVHDFVLEQFNSSQGELQKILHDADRAHSELSPLKLRCQASAACVDLMVWAVKDEQGAENLCVKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVVPSPVLVKLYKCHSQYHTVAGNDIKISVTNEHAESTLNVASGKKSQPSMYEQLRDIAIDNVCRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEPKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIVNLLDPAPEVSALIGKLDFAMSTYLLSVYRLEYMRVLRSSDPARFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVSFNHVHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDVPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLSKHQNWVSGLSQHTGLAMATESVLHYAGYNKQSTSLGATQLTERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSDATGHTSDLNKMMVQELKAALGAGDAQQYTQAMFKLTAMLISSRDCDPQLLHHLCWGPLQMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWQMTVEQKFGLFSAEMKEADPLAASEASQPKPCAPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFCSLLQRSLSLSIGGTAGSMNRHVAAIGPRFKLLTLGLSLLHADVLPNATIRNVLREKIYSTAFDYFSCPPRFPTQGEKRLREDISVMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDIAVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGESSVANWRSKYISLSEKQWKDNVNLAWSISPHLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPADPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASQSQLLAHQFIWNMKTNIYVDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDPEEEGSMQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHLIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFILKVIQNCFLSNRSRTYDMIQYYQNDIPY", "length": 2109, "header": "tr|A0A140T888-1|A0A140T888_BOVIN Isoform 1 of Phosphatidylinositol 4-kinase alpha OS=Bos taurus OX=9913 GN=PI4KA PE=3 SV=3 CANONICAL=A0A140T888-1" }, "locus": { "chromosome": "17", "start_pos": 72268526, "end_pos": 72209161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018572.6", "url": "https://www.ensembl.org/id/ENSBTAT00000018572.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018572.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018572.6" } ] } }, { "isoform_ac": "A0A3Q1M2C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2C3/entry", "sequence": { "sequence": "MMAAAAARGGGGGGGGGSFGSGAGGGASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDSVVPYLLRLLKGLPKVYWVEESTARKGRGTLPVAESFSFCLVTLLSDVAYRDPSLRGEILEALLQVLHVLLGMCQALEIQEKEYLCKHAVPCLLGIVRAFGRHSSSEDSILSRLFPRAPAHSPRVPEELEGVRRRSFNDFRSILPSSLLTVCQEGSLKRKASSASSVAQVSPERGAPPPSPPGGSAFHCLEASYSPNGSTSESDYYFSAVSSSFSVSPLFNGVTYKEFSIPLEMLRELLNLVKKIVEEPVLKSLDAVVTGVIEASPSADLCYGAFSDPLYVAVLRMLRDTLYYMRDLPTSFVKEVHDFVLEQFNSSQGELQKILHDADRAHSELSPLKLRCQASAACVDLMVWAVKDEQGAENLCVKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVVPSPVLVKLYKCHSQYHTVAGNDIKISVTNEHAESTLNVASGKKSQPSMYEQLRDIAIDNVCRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEPKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIVNLLDPAPEVSALIGKLDFAMSTYLLSVYRLEYMRVLRSSDPARFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVSFNHVHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDVPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLSKHQNWVSGLSQHTGLAMATESVLHYAGYNKQSTSLGATQLTERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSDATGHTSDLNKMMVQELKAALGAGDAQQYTQAMFKLTAMLISSRDCDPQLLHHLCWGPLQMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWQMTVEQKFGLFSAEMKEADPLAASEASQPKPCAPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFCSLLQRSLSLSIGGTAGSMNRHVAAIGPRFKLLTLGLSLLHADVLPNATIRNVLREKIYSTAFDYFSCPPRFPTQGEKRLREDISVMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDIAVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGESSVANWRSKYISLSEKQWKDNVNLAWSISPHLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPADPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASQSQLLAHQFIWNMKTNIYVDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDPEEEGSMQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHLIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRHRFSPNMTEREAANFILKVIQNCFLSNRSRTYDMIQYYQNDIPY", "length": 2073, "header": "tr|A0A3Q1M2C3-1|A0A3Q1M2C3_BOVIN Computationally mapped isoform of 1-phosphatidylinositol 4-kinase OS=Bos taurus OX=9913 GN=PI4KA PE=3 SV=1 CANONICAL=A0A140T888-1" }, "locus": { "chromosome": "17", "start_pos": 72268526, "end_pos": 72209161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071533.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071533.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063923.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063923.1" } ] } }, { "isoform_ac": "A0A3Q1MNL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNL7/entry", "sequence": { "sequence": "MMAAAAARGGGGGGGGGSFGSGAGGGASRGFYFNTVLSLARSLAVQRPASLEKVQKLLCMCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDSVVPYLLRLLKGLPKVYWVEESTARKGRGTLPVAESFSFCLVTLLSDVAYRDPSLRGEILEALLQVLHVLLGMCQALEIQEKEYLCKHAVPCLLGIVRAFGRHSSSEDSILSRLFPRAPAHSPRVPEELEGVRRRSFNDFRSILPSSLLTVCQEGSLKRKASSASSVAQVSPERGAPPPSPPGGSAFHCLEGGLRPCGDMVSSLAGSAPPSPTVSAGAHQASFPLQVKKIVEEPVLKSLDAVVTGVIEASPSADLCYGAFSDPLYVAVLRMLRDTLYYMRDLPTSFVKEVHDFVLEQFNSSQGELQKILHDADRAHSELSPLKLRCQASAACVDLMVWAVKDEQGAENLCVKLSEKLQSKTSSKVIIAHLPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVVPSPVLVKLYKCHSQYHTVAGNDIKISVTNEHAESTLNVASGKKSQPSMYEQLRDIAIDNVCRCLKAGLTVDPVIVEAFLASLSNRLYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIIDQLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAANIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLTRRLPPIKEPKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSKEPLRSVLQYNSAMKNDTVTPAELSELRSTIVNLLDPAPEVSALIGKLDFAMSTYLLSVYRLEYMRVLRSSDPARFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTKENEEELERHAQFLLVSFNHVHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSLSLSADIHKDQPYYDIPDVPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSHLQEYLSKHQNWVSGLSQHTGLAMATESVLHYAGYNKQSTSLGATQLTERPACVKKDYSNFMASLNLRNRYAGEVYGMIRFSDATGHTSDLNKMMVQELKAALGAGDAQQYTQAMFKLTAMLISSRDCDPQLLHHLCWGPLQMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWQMTVEQKFGLFSAEMKEADPLAASEASQPKPCAPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFCSLLQRSLSLSIGGTAGSMNRHVAAIGPRFKLLTLGLSLLHADVLPNATIRNVLREKIYSTAFDYFSCPPRFPTQGEKRLREDISVMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLDIAVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGESSVANWRSKYISLSEKQWKDNVNLAWSISPHLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPADPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASQSQLLAHQFIWNMKTNIYVDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDPEEEGSMQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHLIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFILKVIQNCFLSNRSRTYDMIQYYQNDIPY", 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"length": 2069, "header": "tr|A0AAA9S9D7-1|A0A140T888_BOVIN Computationally mapped isoform of Phosphatidylinositol 4-kinase alpha OS=Bos taurus OX=9913 GN=PI4KA PE=3 SV=1 CANONICAL=A0A140T888-1" }, "locus": { "chromosome": "17", "start_pos": 72268948, "end_pos": 72209161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089151.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089151.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080545.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080545.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1342, "start_aa": "Thr", "end_pos": 1342, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1342", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 511, "start_aa": "Thr", "end_pos": 511, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr511", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1483248", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483248", "resource": "Reactome", "description": "Synthesis of PIPs at the ER membrane" }, { "id": "R-BTA-1660514", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1660514", "resource": "Reactome", "description": "Synthesis of PIPs at the Golgi membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ], "pmid": "" }, { "name": "1-phosphatidylinositol 4-kinase activity", "id": "GO:0004430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004430", "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A140T888", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1374, "end_pos": 1376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1750, "end_pos": 1752, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2071, "end_pos": 2073, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2092, "end_pos": 2094, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 860, "end_pos": 862, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-1675813", "name": "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-426639" ], "output_participant_list": [ "R-ALL-1806234" ], "enzyme_list": [ "F1MK34-1", "A0A140T888-1" ], "evidence": [ { "id": "R-BTA-1675813", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1675813" } ] }, { "id": "R-BTA-1676185", "name": "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane, cytosol", "input_participant_list": [ "R-ALL-1524146" ], "output_participant_list": [], "enzyme_list": [ "F1MK34-1", "A0A140T888-1" ], "evidence": [ { "id": "R-BTA-1676185", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1676185" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1524146", "participant_name": "PI [Golgi membrane]", "crossref": [ { "id": "57880", "database": "ChEBI", "url": "" }, { "id": "C01194", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1806234", "participant_name": "PI4P [endoplasmic reticulum membrane]", "crossref": [ { "id": "17526", "database": "ChEBI", "url": "" }, { "id": "4496", "database": "PubChem Substance", "url": "" }, { "id": "C01277", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-426639", "participant_name": "PI [endoplasmic reticulum membrane]", "crossref": [ { "id": "57880", "database": "ChEBI", "url": "" }, { "id": "C01194", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T888", "gene_name": "PI4KA", "activity": [ { "ec_number": "2.7.1.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A140T888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ] }, { "ec_number": "2.7.1.67", "activity": "", "evidence": [ { "id": "A0A140T888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T888" } ] } ] }, { "uniprot_ac": "F1MK34", "gene_name": "PI4K2B", "activity": [ { "ec_number": "2.7.1.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1MK34", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A140T890/entry", "sequence": { "sequence": "MASTICFILWVVFVTDTVWTRSVRQVYEASDPEDWTMHDFDCPRECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLENNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQHNKLLDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDAGLPSSGFNVSSILDLQLSHNQLTKVPKISAHLQHLYLDHNKIRNVNVSVICPSTPTTLPVEDSFSYGPHLRYLRLDGNEIKPPIPMDLMTCFRLLQAVII", "length": 352, "header": "tr|A0A140T890-1|A0A140T890_BOVIN Isoform 1 of Keratocan OS=Bos taurus OX=9913 GN=KERA PE=3 SV=1 CANONICAL=A0A140T890-1" }, "locus": { "chromosome": "5", "start_pos": 20935206, "end_pos": 20929976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019066.3", "url": "https://www.ensembl.org/id/ENSBTAT00000019066.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019066.2", "url": "https://www.ensembl.org/id/ENSBTAP00000019066.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" }, { "id": "R-BTA-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IJZ2-1", "protein_name": "Keratocan", "gene_name": "Kera", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATSICLLLWVLLIANTVWTQSVRQAYEVLDLEEWDVHDDFFCPRECFCPPSFPTALYCENRGLREIPAIPSRIWYLYLENNQIETIPEKPFQNATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQHNKLLDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEAIPENYFNVIPKVAFLRLNHNKLSDAGLPSKGFDVSSILDLQLSHNQLTNFPRINANLQHLHLDHNKIKNVNISVICPTTLRAEQDAFIHGPQLSYLRLDGNEIKPPIPIDIVTCFKLLQAFII", "length": 351 }, "evidence": [ { "id": 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"sequence": "MATPNCLILWVLLIADTVWTQSVRQAYEIQDPEDWDVHDDFYCPRECFCPPSFPTALYCENRGLTEIPPIPSRIWYLYLENNLIESIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQHNKLLDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDAGLPSRGFDVSSILDLQLSYNQLTNFPRINANLQHLHLDHNKIKNVNMSVICPTTLRAEQDAFIHGPQLSYLRLDGNEIKPPIPIDLVACFKLLQAFII", "length": 351 }, "evidence": [ { "id": "A0A140T890", "url": "https://omabrowser.org/oma/group/A0A140T890/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O42235-1", "protein_name": "Keratocan", "gene_name": "KERA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMTLKVCPSLLLLFLVHSVWTRTVRQVYNELDPEHWSHYTFECPQECFCPPSFPNALYCDNKGLKEIPAIPARIWYLYLQNNLIETISEKPFVNATHLRWINLNKNKITNNGIESGVLSKLKRLLYLFLEDNELEEVPAPLPVGLEQLRLARNKISRIPEGVFSNLENLTMLDLHQNNLLDSALQSDTFQGLNSLMQLNIAKNSLKKMPLSIPANTLQLFLDNNSIEVIPENYFSAIPKVTFLRLNYNKLSDDGIPPNGFNVSSILDLQLSHNQLTKIPPINAHLEHLHLDHNRIKSVNGTQICPVSIAVAEDYGLYGNIPRLRYLRLDGNEIQPPIPLDIMICFQLLQAVVI", "length": 353 }, "evidence": [ { "id": "A0A140T890", "url": "https://omabrowser.org/oma/group/A0A140T890/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O60938-1", "protein_name": "Keratocan", "gene_name": "KERA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MSRLNLTMEVLLVAFVAVFLTSQVHSDEIPYEHLMSQLQACPKECNCPPNFPNAVYCDNKGLKSIPVIPPYTWYLYLQNNLIDVLSANALRNATQLKWINLNRNKITTEGLEVDALRAMSNLVHLYMEDNLLSSIPSPLPAKLEQLRLSRNKISKIPPGVFSGMGHLTLLDLQSNKLQDDAVTEVSLKGLNNLIQINLAKNQLNSMPLGLPPTTTQIFLDGNNIEKIPAEYFKGLPKVASLRLNRNKLANGGIPKNVFNLSSILDLQLSHNQLTEVPVISSGLEHLHLDHNKIKSVNSSDICPPGVLDDHLEEKSPRLRYLRLDGNEIQPPIPRELMTCFRLLRAVVI", "length": 348 }, "evidence": [ { "id": "A0A140T890", "url": "https://omabrowser.org/oma/group/A0A140T890/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A140T890", "url": "https://www.uniprot.org/uniprotkb/A0A140T890" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": 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"url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 75, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RYU3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYU3#function" }, { "database": "UniProtKB", "id": "ARBA00055793", "url": "https://www.uniprot.org/uniprotkb/ARBA00055793#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HSPB6", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A1", "locus": { "chromosome": "18", "start_pos": 46466906, "end_pos": 46469730, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018598", "url": "https://www.ensembl.org/id/ENSBTAG00000018598" } ] } 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"MSPGGSPRGGHRAYYKAAAALAGALRNLGRRRSRMEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPAALAPYYLRAPSVALPTAQVSTDPGHFSVLLDVKHFSPEEIAVKVVGDHVEVHARHEERPVSPLAGAGPERDEHGYIAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPAPAQAPLQSPPGAAAK", "length": 209, "header": "tr|A0A140T8A1-1|A0A140T8A1_BOVIN Isoform 1 of Heat shock protein family B (small) member 6 OS=Bos taurus OX=9913 GN=HSPB6 PE=3 SV=3 CANONICAL=A0A140T8A1-1" }, "locus": { "chromosome": "18", "start_pos": 46469531, "end_pos": 46467818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024749.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024749.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024749.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024749.7" } ] } }, { "isoform_ac": "A0AAA9RYU3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYU3/entry", "sequence": { "sequence": "METRRGEGGSCNLRKGGVDTQKWGRSTNNCWGLKQSRNSSGRVERGLWRIREEASWRFLAEVSTDPGHFSVLLDVKHFSPEEIAVKVVGDHVEVHARHEERPDEHGYIAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPAPAQAPLQSPPGAAAK", "length": 159, "header": "tr|A0AAA9RYU3-1|A0A140T8A1_BOVIN Computationally mapped isoform of Heat shock protein family B (small) member 6 OS=Bos taurus OX=9913 GN=HSPB6 PE=3 SV=1 CANONICAL=A0A140T8A1-1" }, "locus": { "chromosome": "18", "start_pos": 46468792, "end_pos": 46467818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130666.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130666.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076459.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076459.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": 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"A0A140T8A1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A1" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A140T8A1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 209, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A140T8A1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A140T8A1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A140T8A1", "database": "UniProtKB", "url": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A140T8A2-1", "uniprot_ac": "A0A140T8A2", "uniprot_id": "A0A140T8A2_BOVIN", "mass": { "chemical_mass": 51767.0, "monoisotopic_mass": 51767.0 }, "refseq": { "ac": "NP_001071567", "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567" }, "gene_names": [ { "name": "DPH2", "type": "recommended", "evidence": [ { "id": "A0A140T8A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ] }, { "name": "DPH2", "type": "synonym", "evidence": [ { "id": "NP_001071567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567" } ] } ], "protein_names": [ { "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "type": "recommended", "evidence": [ { "id": "A0A140T8A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2/entry#names_and_taxonomy" } ] }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001071567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567" } ] }, { "name": "DPH2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001071567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567" } ] }, { "name": "S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2", "type": "synonym", "evidence": [ { "id": "NP_001071567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567" } ] }, { "name": "diphthamide biosynthesis protein 2", "type": "synonym", "evidence": [ { "id": "NP_001071567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567" } ] }, { "name": "diphtheria toxin resistance protein 2", "type": "synonym", "evidence": [ { "id": "NP_001071567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567" } ] } ], "function": [ { "annotation": "Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2#function" }, { "database": "UniProtKB", "id": "RU364133", "url": "https://www.uniprot.org/uniprotkb/RU364133#function" }, { "database": "UniProtKB", "id": "ARBA00045159", "url": "https://www.uniprot.org/uniprotkb/ARBA00045159#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DPH2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2", "locus": { "chromosome": "3", "start_pos": 102085998, "end_pos": 102089549, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018888", "url": "https://www.ensembl.org/id/ENSBTAG00000018888" } ] } } ], "crossref": [ { "id": "A0A140T8A2", "url": "https://alphafold.ebi.ac.uk/entry/A0A140T8A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018888", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018888", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768224", "url": "https://www.ncbi.nlm.nih.gov/gene/768224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:768224", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768224", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QIWNENH", "url": "https://omabrowser.org/oma/group/QIWNENH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140T8A2", "url": "https://www.orthodb.org/?gene=A0A140T8A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10762", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10762", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10762:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10762:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01866", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01866", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5358493", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5358493", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001071567", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIU8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESTFSSPAEAALQREAGSAGLRTSLGDLDRVYELERVVGFVRDLGCQRVALQFPDQLLGDAGAVAALLEEATGSKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPARPLPVAFVLGQRSVALELCAKAFEAQNPDPTAPVVLLSEPSCAHALEALATLLRPRYLDLLVSSPALPLPAGSFNPNPEPLERFGRRFPLAPGRCLEEYGAFYVGGSEAISDPDLDPDLSRLLLGWAPGRPFSSCCPDTGRTQDEGVRAGRLRARRRYLIERARDARVVGLLAGTLGVARHREALAHLRNLTQAAGKRSYVLALGRPTPAKLANFPEVDVFVLLACPLGTLAPQPSGSFFRPVLAPCELEAACNPAWPPPGLAPHLTHYTDLLPGSPFHVPLPPPDSELWDAPDVSLITGDLRPPPAWKPSDDPGCSALTPKPQLELAESSPAASFLSSRSWKGLQPSLGQTPVTGAVSGRRGIAIAYEDEGNS", "length": 489, "header": "tr|A0A140T8A2-1|A0A140T8A2_BOVIN Isoform 1 of 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 OS=Bos taurus OX=9913 GN=DPH2 PE=3 SV=1 CANONICAL=A0A140T8A2-1" }, "isoforms": [ { "isoform_ac": "A0A140T8A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2/entry", "sequence": { "sequence": "MESTFSSPAEAALQREAGSAGLRTSLGDLDRVYELERVVGFVRDLGCQRVALQFPDQLLGDAGAVAALLEEATGSKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPARPLPVAFVLGQRSVALELCAKAFEAQNPDPTAPVVLLSEPSCAHALEALATLLRPRYLDLLVSSPALPLPAGSFNPNPEPLERFGRRFPLAPGRCLEEYGAFYVGGSEAISDPDLDPDLSRLLLGWAPGRPFSSCCPDTGRTQDEGVRAGRLRARRRYLIERARDARVVGLLAGTLGVARHREALAHLRNLTQAAGKRSYVLALGRPTPAKLANFPEVDVFVLLACPLGTLAPQPSGSFFRPVLAPCELEAACNPAWPPPGLAPHLTHYTDLLPGSPFHVPLPPPDSELWDAPDVSLITGDLRPPPAWKPSDDPGCSALTPKPQLELAESSPAASFLSSRSWKGLQPSLGQTPVTGAVSGRRGIAIAYEDEGNS", "length": 489, "header": "tr|A0A140T8A2-1|A0A140T8A2_BOVIN Isoform 1 of 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 OS=Bos taurus OX=9913 GN=DPH2 PE=3 SV=1 CANONICAL=A0A140T8A2-1" }, "locus": { "chromosome": "3", "start_pos": 102089360, "end_pos": 102086805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025143.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025143.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025143.5", "url": "https://www.ensembl.org/id/ENSBTAP00000025143.5" } ] } }, { "isoform_ac": "A0AAA9TIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIU8/entry", "sequence": { "sequence": "MESTFSSPAEAALQREAGSAGLRTSLGDLDRVYELERVVGFVRDLGCQRVALQFPDQLLGDAGAVAALLEEATGSKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPARPLPVAFVLGQRSVALELCAKAFEAQNPDPTAPVVLLSEPSCAHALGSPFHVPLPPPDSELWDAPDVSLITGDLRPPPAWKPSDDPGCSALTPKPQLELAESSPAASFLSSRSWKGLQPSLGQTPVTGAVSGRRGIAIAYEDEGNS", "length": 261, "header": "tr|A0AAA9TIU8-1|A0A140T8A2_BOVIN Computationally mapped isoform of 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 OS=Bos taurus OX=9913 GN=DPH2 PE=3 SV=1 CANONICAL=A0A140T8A2-1" }, "locus": { "chromosome": "3", "start_pos": 102089360, "end_pos": 102086805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099382.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099382.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098383.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098383.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:768224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768224", "resource": "KEGG Pathway" }, { "id": "R-BTA-5358493", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5358493", "resource": "Reactome", "description": "Synthesis of diphthamide-EEF2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W2Z0-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "DPH2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESTFSSPAEAALQREAGAAGRRTPLGDLDRVYELDRVVGFVSDLGCHRVALQFPDQLLGDAGAVAARLEEVTGSKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPARPLPVAFVLGQRSVALELCAKAFEAQNPDPAAPVVLLSEPACAHALEALATLLRPRYLDLLVSSPALPLPGGSRSPDPEPLERFGRRFPLAPGRRLEEYGAFYVGGSEAISDPDLDPDLSRLLLGWAPGRPFSSCCPDTGRTQDEGARAGRLRARRRYLVERARDARVVGLLAGTLGVARHREALAHLRSLTQAAGKRSYVLALGRPTPAKLANFPEVDVFVLLACPLSALAPQSSGNFFRPVLAPCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVPLPPPDSELWDTPDVSLITGGLRPPPAWTPSTDSGCSALTLRPQQELVESSPAASFLSSRSWQGLQPRLGQTPVTGAVSGRRGIAIAYEDEGSS", "length": 489 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4QN59-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "dph2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTDAFSSSSEAVLQRSVTSTHSFHPSGDLLLLYQTPETCRFITSNHFKKVALQFPDELLPDAVRVSAEIEDKTKAKTYILGDTSYGSCCVDEVAAEHVGADCIVHYGSSCLSPCRRLPLLYVFGKRPIDVHQCASSFKELYPNLQSHIIVLFDVTYSHAIDDLRTLLCDVYPNVVVSRLKTDHSCGAELIQDSCVDLQSNDDGVIFKFGRQFRIKEGQTVNDYSIFYIGQEGLTLTNFMMSWNNCVFSSFNPETSTGRVESVQINKALMKRYYAIERAKDASVVGILVGTLGVANYLIIIEQLKDTIQRAGKKSYMFAMGKINVPKLANFLEIDIYVLVACPENSLLDSSEFYRPVVTPFEMELACNKHREWTGEYVTDFRELLPGGSSHVGFPEPSQSATEEETTDVSLITGALRSCSTNSSEMMHNSETSSLVLRNQTLTVANTNAAASFLAGRSWQGLEPKLGQTPVVKAVKGQRGIAIAYEEEGNEDASTQQKL", "length": 498 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B0G132-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "dph2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSAAPPPSIYTESFSTSSNNTTESESINVEETRENILSGFSFEEYFQVSESISVIIKNNFKKIALQLPDYLLWASSELSNKIQNSVPLEYGIKVFILGDTSYGSCCVDEVTSSHLKSDFIIHYGHSCLSPSSKIPVQYVFGKKKNFNVDKFSIELNKLVESKKEENFVIFYDLLYHHNRDSIENLYKNNDNIIVTNINNFNNIYLNNSFKNNKLNETQNCNNNYNNDCCGSDNNNNNNDSGCCGGNNNNNNNNSGCCQSQSQQQQQQNDCCQQKLNNEINNENDNNNEELISGRKIEFKNEKDIKKFNFIWIGEESLTLTNLLMNFNQQMVYRYYIDDNKLLQETLPRNKSLMRRYHISEKCKDASIIGIVVSTLSVQKYSETIDGLKKLIIASGKKPYVFVVGRLNVPKLANFSEIDIYVIVACHENTMVDSKDFYKPIATPFELNLSLRNEKWTGEYITDFGRVFPKLIKDLSFDEDDENKCEIPEDQVEDDQGNIHHFSLVTGRIVIQNKNQSTLQQQQQQQQTQQSGDLISVNNQFKQVSLVGEHLSNKTYKGLDMRIGETPVTTAIEGMSGIPKNYNTDKNNL", "length": 588 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P32461-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "DPH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEVAPALSTTQSDVAFQKVETHEIDRSSYLGPCYNSDELMQLISAYYNVEPLVGYLEQHPEYQNVTLQFPDDLIKDSSLIVRLLQSKFPHGKIKFWVLADTAYSACCVDEVAAEHVHAEVVVHFGDACLNAIQNLPVVYSFGTPFLDLALVVENFQRAFPDLSSKICLMANAPFSKHLSQLYNILKGDLHYTNIIYSQVNTSAVEEKFVTILDTFHVPEDVDQVGVFEKNSVLFGQHDKADNISPEDYHLFHLTTPQDPRLLYLSTVFQSVHIFDPALPGMVTGPFPSLMRRYKYMHVARTAGCIGILVNTLSLRNTRETINELVKLIKTREKKHYLFVVGKPNVAKLANFEDIDIWCILGCSQSGIIVDQFNEFYKPIITPYELNLALSEEVTWTGKWVVDFRDAIDEIEQNLGGQDTISASTTSDEPEFDVVRGRYTSTSRPLRALTHLELEAADDDDSKQLTTRHTASGAVIKGTVSTSASALQNRSWKGLGSDFDSTEVDNTGADIEEGISGVARGYGFDREDAMKKENK", "length": 534 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q002B5-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "DPH2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESTFSSPAEAALQREAGVPGLFTPPEDLDRVYELERVTKFVCDLGCQRVALQFPDQLLGDAGAVAVRLEEVTGSKMFILGDTAYGSCCVDVLGAEQAGAEALVHFGPACLSPPASLLPITFVLGQRSVALELCAKAFEARNPDPTAPVVLLSEPACAHALEALATLLRPKYQDLLISSPALPLPVGSPSSQPEPLERFGRRFPLSPGRCLEEYGAFYVGGSQASSDPVLDPDLSRLLLGWTPGRPFISCCPDTGQTQDQGVQAGRLRARRLYLIERARDAHVVGLLAGTLGVAQHREALAHLRKLTEAAGKRSYVLALGRPTPAKLANFPEMDIFVLLACPLGALAPQPSGGFFRPILTPCELEAACNPAWPPPGLAPHLTHYAELLPGSPFYVPLPPPESELWDTPDVSLISGDLRPPPSWKSSSDTGCSALTPRPQLELAESSPAASFLSSRSWQGLEPRLGQTPVKEAVQGRRGIAIAYEDEGSG", "length": 489 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q568Y2-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "Dph2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESTFSSPAEAALQREAGVPGQFTPPEDLDRVYELERVTRFICDLGCQRVALQFPDQLLGDAGAVAARLEEVTGSKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPASLLPITFVLGRRPVALELCAKAFEAQNPDPTALVVLLSEPACAHALEPLATLLRPKYQDLLISSPALPLPVGSLSSQPESLERFGRRFPLNPGRSLEEYGAFYVGASQASSDPNLDPDLSRLLLGWTPGRPFFSCCPDTGQTQDQGAKAGRLRARRLYLVERARDARVVGLLVGTLGVAQHLEALAHLRKLTEAAGKRSYVLALGKPTPAKLANFPEMDVFVLLACPLGALTLQPSGGFFRPILTPCELEAACNPAWPPPGLAPHLTHYAELLPGSPFHVPLPPPESELWDTPDVSLISGELRPPPPWKSSDDTKCSALTPRPQLELAESSPAASFLSSRSWQGLEPRLGQTPVKEAVQGRRGIAIAYEDEGSS", "length": 489 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BQC3-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "DPH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESMFSSPAEAALQRETGVPGLLTPLPDLDGVYELERVAGFVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFILGDTAYGSCCVDVLGAEQAGAQALIHFGPACLSPPARPLPVAFVLRQRSVALELCVKAFEAQNPDPKAPVVLLSEPACAHALEALATLLRPRYLDLLVSSPAFPQPVGSLSPEPMPLERFGRRFPLAPGRRLEEYGAFYVGGSKASPDPDLDPDLSRLLLGWAPGQPFSSCCPDTGKTQDEGARAGRLRARRRYLVERARDARVVGLLAGTLGVAQHREALAHLRNLTQAAGKRSYVLALGRPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILAPCELEAACNPAWPPPGLAPHLTHYADLLPGSPFHVALPPPESELWETPDVSLITGDLRPPPAWKSSNDHGSLALTPRPQLELAESSPAASFLSSRSWQGLEPRLGQTPVTEAVSGRRGIAIAYEDEGSG", "length": 489 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CR25-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "Dph2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESTFSSPAEAALQREAGVPGQFTPPEDLDRVYELERVTKFVCDLGCQRVTLQFPDQLLGDAGAVAARLEEVTGAKMFILGDTAYGSCCVDVLGAEQAGAQALVHFGPACLSPPASQLPITFVLGQRPVALELCAKAFEAQNPDPTAPVVLLSEPACAHALEPLAMLLLPKYQDLLISRPALPLPVGSPSSQPESLERFGRCFPLNPGRRLEEYGAFYVGASQASSDSSLDPDLSRLLLGWTPGRPFFSCCPDTGQTQDQGAKAGRLRARRLYLIERARDARVVGLLAGTLGVARHREALAHLRKLTEAAGKRSYVLAVGKPTPAKLANFPEMDVFVLLACPLGALAPQPSGGFFRPVLTPCELEAACNPAWPPPGLAPHLTHYAELLPGSPFHVPLPPPESELWDTPDVSLISGELRPPPPWKSSDDTRCSALIPRPQLELAESSPAASFLSSRNWQGLEPRLGQTPVKEAVRGRRGIAIAYEDEGSS", "length": 489 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M1A5-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MELEFESKYEINRTAEFIISKSFTRIALQFPDELLKDSTKVVSALKSKTRLLTDREVRFFVMADTTYGSCCIDEVGALHIDSECVVHYGQTCLSPTSVLPAFFVFGKASINVSSCVKHLIDYASKSDKPIMILYGLEYAHVIPQIREELGLSKTDSQLSVANVLCSFISPSKDPRESMEHPRPYSESDSSDSLSSSRSYRLGGLTWDLPEGSKIEDYLLFWIGSDSSAFANVVLTFNGCDIVRYDAEEDSLVTEFYQQRRILKRRYYLVEKAKDANIIGILVGTLGVAGYLHMIHHMQALISAAGKKSYILAMGRPNPAKLANFPECDVFIYISCAQTALLDSKEFMSPVITPFEANLAFSRGSEWTGAYLMHFQDVINSVKSESEAHIGSEEPRFSFFQGGYVEDHKTNDQAKNGEEDTGETMTLVQAAEKALQLRGNDHNSLTKQTAAKSGPEYFLNRVYRGLEINSENTLPEPYIVGRSGKASGYKHE", "length": 491 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VFE9-1", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "gene_name": "Dph2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSSETSASAFSSSDTAALERQAEVEQPVTLEQIWNENHRRSSVDWIRKSGYKRVCLQFPDDYLPHSNAISVGLKELLAPEDVKVFILADTTYGSCCVDEIAAAHVDADSVIHFGNACRSRAARLPVLYLYPELPLDVNVLLSKLQGLRAESIDRQVCVYLDIGYQHVYGEKLKKQLSEILEPKELLLELFPPIEAESTTTRETTNLERICIFIGADNQRFANLSLTAPAAVQWHIYDGSSDSLSSKNPLTAQFIRRRYFHIEKCKDAQTLGLIVATLSAEGYLDVVTRLQTMAKGRGIKTQLISVGRINPAKLANFLEIDCFVLIGCPFNNMYDSKEYYKPIVSVFEAEMALNPAWHMRYPEAYVTDFKQLLPEGRSFLPFDAADIPENDVSLVSGRLRGAVNDSLETGGDPASLALATQAKMALMTTDTGLSFEDRTWQGLDPALGQTEPAKLQQGLSGIPINYSHQ", "length": 469 }, "evidence": [ { "id": "A0A140T8A2", "url": "https://omabrowser.org/oma/group/A0A140T8A2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "pmid": "" }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase complex", "id": "GO:0120513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120513", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "pmid": "" }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase activity", "id": "GO:0090560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090560", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8A2", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1ML82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVP9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDMILILCLLKMSSAVPAFPQQPGIPGMASLSLETMRQLGSLQGLNLLSQYSRFGFGKSFNSLWMNGLLPPHSSFPWMRPREHETQQYEYSLPVHPPPLPSQPSLQPQQPGQKPFLQPTVVTSMQNAVQKGVPQPPIYQGHPPLQQAEGPMVEQQVAPSEKPPTTELPGMDFADLQDPPMFPIAHLISRGPMPQNKPSQLYPGIFYVTYGANQLGGRGDPLAYGAIFPGFGGMRPRLGGMPHNPDMGGDFTLEFDSPVAATKGPEKGEGGAQDSPVPEAHLADPESPALLSELAPGALEGLLANPEGNIPNLARGPAGRSRGFLRGVTPAAADPLMTPGLAEVYETYGADETTTLGLQEETTVDSTATPDTQHTLMPRNKAQQPQIKHDAWHFQEP", "length": 397, "header": "tr|A0A140T8D3-1|A0A140T8D3_BOVIN Isoform 1 of Ameloblastin OS=Bos taurus OX=9913 GN=AMBN PE=3 SV=2 CANONICAL=A0A140T8D3-1" }, "isoforms": [ { "isoform_ac": "A0A140T8D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D3/entry", "sequence": { "sequence": "MKDMILILCLLKMSSAVPAFPQQPGIPGMASLSLETMRQLGSLQGLNLLSQYSRFGFGKSFNSLWMNGLLPPHSSFPWMRPREHETQQYEYSLPVHPPPLPSQPSLQPQQPGQKPFLQPTVVTSMQNAVQKGVPQPPIYQGHPPLQQAEGPMVEQQVAPSEKPPTTELPGMDFADLQDPPMFPIAHLISRGPMPQNKPSQLYPGIFYVTYGANQLGGRGDPLAYGAIFPGFGGMRPRLGGMPHNPDMGGDFTLEFDSPVAATKGPEKGEGGAQDSPVPEAHLADPESPALLSELAPGALEGLLANPEGNIPNLARGPAGRSRGFLRGVTPAAADPLMTPGLAEVYETYGADETTTLGLQEETTVDSTATPDTQHTLMPRNKAQQPQIKHDAWHFQEP", "length": 397, "header": "tr|A0A140T8D3-1|A0A140T8D3_BOVIN Isoform 1 of Ameloblastin OS=Bos taurus OX=9913 GN=AMBN PE=3 SV=2 CANONICAL=A0A140T8D3-1" }, "locus": { "chromosome": "6", "start_pos": 85979235, "end_pos": 85969111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053975.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053975.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052338.3", "url": 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"ENSBTAP00000071734.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071734.1" } ] } }, { "isoform_ac": "A0AAA9RVP9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVP9/entry", "sequence": { "sequence": "MILILCLLKMSSAVPAFPQQPGIPGMASLSLETMRQLGSLQGLNLLSQYSRFGFGKSFNSLWMNGLLPPHSSFPWMRPREHETQQPSLQPQQPGQKPFLQPTVVTSMQNAVQKGVPQPPIYQGHPPLQQAEGPMVEQQVAPSEKPPTTELPGMDFADLQDPPMFPIAHLISRGPMPQNKPSQLYPGIFYVTYGANQLNAPARLGIMSSEEMGGGRGDPLAYGAIFPGFGGMRPRLGGMPHNPDMGGDFTLEFDSPVAATKGPEKGEGGAQDSPVPEAHLADPESPALLSELAPGALEGLLANPEGNIPNLARGPAGRSRGFLRGVTPAAADPLMTPGLAEVYETYGADETTTLGLQEETTVDSTATPDTQHTLMPRNKAQQPQIKHDAWHFQEP", "length": 394, "header": "tr|A0AAA9RVP9-1|A0A140T8D3_BOVIN Computationally mapped isoform of Ameloblastin OS=Bos taurus OX=9913 GN=AMBN PE=3 SV=1 CANONICAL=A0A140T8D3-1" }, "locus": { "chromosome": "6", "start_pos": 85979235, "end_pos": 85969120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102647.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102647.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075170.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075170.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8D3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D3" } ], "pmid": "" }, { "name": "odontogenesis of dentin-containing tooth", "id": "GO:0042475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042475", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8D3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D3" } ], "pmid": "" }, { "name": "biomineral tissue development", "id": "GO:0031214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031214", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8D3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8D3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D3" } ], "pmid": "" }, { "name": "structural constituent of tooth enamel", "id": "GO:0030345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030345", "evidence": [ { "database": "UniProtKB", "id": "A0A140T8D3", "url": "https://www.uniprot.org/uniprotkb/A0A140T8D3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A140T8D3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 397, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A140T8D3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A140T8D3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A2Z2AM52-1", "uniprot_ac": "A0A2Z2AM52", "uniprot_id": "A0A2Z2AM52_BOVIN", "mass": { "chemical_mass": 27093.0, "monoisotopic_mass": 27093.0 }, "refseq": {}, "gene_names": [ { "name": "KLRC1", "type": "recommended", "evidence": [ { "id": "A0A2Z2AM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ] } ], "protein_names": [ { "name": "Killer cell lectin-like receptor subfamily C, member 1", "type": "synonym", "evidence": [ { "id": "A0A2Z2AM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLRC1", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000054633", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2424491", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2424491", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2Z2AM52-1", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNQGATYAELKGVKNSKRQKRKPKVSKSSISMTEQELTYVELNFQNAPQNLHGNDRNHRSKGSPSPPEKFIAGILGIICLVLMSIVVRMIVVTPSTVIRKQNYSSLTTRLQKECHCGHCPKDWITYSNNCYYTSLEKKSWNESLISCANKNSTLLYIDNEEEMKFLMSLSIISWIQVSREGRGRPWKWLNGSTCNLQITDNVPDEHNCAVQYLWGIKAEDCQFPNTYHCKHKLEN", "length": 236, "header": "tr|A0A2Z2AM52-1|A0A2Z2AM52_BOVIN Isoform 1 of Killer cell lectin-like receptor subfamily C, member 1 OS=Bos taurus OX=9913 GN=KLRC1 PE=4 SV=1 CANONICAL=A0A2Z2AM52-1" }, "isoforms": [ { "isoform_ac": "A0A2Z2AM52-1", "url": 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"R-BTA-2424491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2424491", "resource": "Reactome", "description": "DAP12 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUX8-1", "protein_name": "Killer cell lectin like receptor C1", "gene_name": "Klrc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNDRVTYAELNVAKNSRYQHNKPRGSRSSISVIEQEIVYADFSFKNPSQEQTRICRDCHCKGFPSPPEKLIAGTLGFISFVLIVAVVVITTVATPYTETKAQINSSMTRTYQDINHNLFSARPCTRCPDDWISYSHNCYYISVERKSWNDGLTSCISKNCSLLHIDSEEEQAFLQSFSLVSWTGFFRKSRSQPWVWENGSTFKPKITEMLHDEYNCIMMSTSGLTAENCTILHPYVCKCKLTN", "length": 244 }, "evidence": [ { "id": "A0A2Z2AM52", "url": "https://omabrowser.org/oma/group/A0A2Z2AM52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q07444-1", "protein_name": "NKG2-E type II integral membrane protein", "gene_name": "KLRC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKQRGTFSEVSLAQDPKWQQRKPKGNKSSISGTEQEIFQVELNLQNASLNHQGIDKIYDCQGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPFLEQNNSSPNARTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLQACASKNSSSLLCIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLNS", "length": 240 }, "evidence": [ { "id": "A0A2Z2AM52", "url": "https://omabrowser.org/oma/group/A0A2Z2AM52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "natural killer cell mediated immunity", "id": "GO:0002228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002228", "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045954", "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "pmid": "" }, { "name": "stimulatory C-type lectin receptor signaling pathway", "id": "GO:0002223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002223", "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A2Z2AM52", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A2Z2AM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2Z2AM52" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 231, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"yes" } }, { "uniprot_canonical_ac": "A0A3Q1LF69-1", "uniprot_ac": "A0A3Q1LF69", "uniprot_id": "A0A3Q1LF69_BOVIN", "mass": { "chemical_mass": 157639.0, "monoisotopic_mass": 157639.0 }, "refseq": {}, "gene_names": [ { "name": "CLSPN", "type": "recommended", "evidence": [ { "id": "A0A3Q1LF69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF69" } ] } ], "protein_names": [ { "name": "Claspin", "type": "synonym", "evidence": [ { "id": "A0A3Q1LF69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF69/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF69" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLSPN", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF69", "locus": { "chromosome": "3", "start_pos": 110048344, "end_pos": 110020609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002826", "url": "https://www.ensembl.org/id/ENSBTAG00000002826" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002826", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002826", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR024146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LF69", "url": "https://www.orthodb.org/?gene=A0A3Q1LF69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M4G6", "url": "https://www.orthodb.org/?gene=A0A3Q1M4G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14396:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14396:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-BTA-111465", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111465", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-176187", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176187", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LF69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LF69-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4G6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAWSHVESLLRIGANHRGRGLHSGWARKLERRCLAGDGGSGRVLTSKATGDLFRPEWRAEETGVMTGEVVSEVHLEINDSKLISQEETDSPSDSGQGSCETIGPLSEQDSDEEIFVSRKLKSRKVLQESDSEREDPVSPEKTTYDAAEEEDKENLCAEKNGEARRIHKTLADSDESDVEESLCQENSETQMTPCLEMGLQSENSVDFTVDRKISKKPLCGKEGIGGKAKVKSKRRLEKEERKMEKIRQLKKKETKNEEDDVKQPFNDSGCLLVDKDLFETGLEEEDHSPLEDEESLESIRAAVKNKVKKHKKKELSLESGVYSFEEETELSKGTTRKERKAAKLSKEELKKLHSETQRLIRESALNLPYHMPENKTVHEFFKRKPRPTCQGNAMALLKSTKYQASHHKETIDTENSTEVNGDHHSKDSAQTTGAGCEMEINALPAVSKEPQITAKSDEPCGKDLTGSEELEVPEKQEQSDARPPPGDVSVARQECSVLGNKDSEEHQTEGLVAPEPHALEEEKGLRKTEAADEKAEEPSQQNGSTAAVPPEKARRFTVDRLRQLGVDVFRKPQLGADRDSFVILEEPETNRELEALKQRFWKHANPTARPRAGQKVNVNIIVKDVGADGKEELKADVVPMTLAAEKLDGASHTKPGEKLQVLKAKLQEAMKLRRLEERQKRQALLKLDNEDGFEEEEEEEEEEEEMTDDSEEDGEEEGEEALEEEEEKEEGAEEEGNEETAEFLLGGEEIETKDEKEIDKENDDGSGEIGKSVGLSVPKPLSSDSTFLLFKDSSSKMGYSPSEEKSEIDENSGKRPSKLDEDDSCSLLTKESSHNSSFELIGSTLPSYQPCNRQTGRGTSLFPTAGGFRSPSPGLFRASLVSSASKSSGKLSEPSLPIEDSQDLYNASPEPKTLFLGAGDFQFCLEDDTQSQLLDADGFLNVRNHRNQYQDLKPRLPLASMDENAMDANMDELLDLCTGKFASQAEKPLPGKSDKKENMEELLDLCSGKFTSQDASTLDPSELNKQEKESSLGDPMEEALALCSGSFPTDREEEGEEEEFGDFRLVPNDNEFDSDEDEHSESDKEDLTPEDREDDDEEDLLQQSEKSKRQMRLKKYLEDEAEVSGSDMGSEDEYDGEELDEYEEDVIDEVLPSDEELQSQVKKIHMKTMLDDDKRELRLYQERYLADGDLHSDGPGRMRRFRWKNIDDASQMDLFHRDSDDDQIEEQLDETEARWRKERIEREQWLRDHAQQGKIAAEDEEEIGEDSQFMMLAKKVTAKALQKNVSHTVVIQESKSLFRNPFEAIKPGSDNQLKTGSLLNQPKAVLQKLAALSDLNPSAPRNSRNFVFHTLSPVKAEAAKESSKPRVRRRGPSLMTSTSPKRLKIDDSTSESKQSIFRYLES", "length": 1403, "header": "tr|A0A3Q1LF69-1|A0A3Q1LF69_BOVIN Isoform 1 of Claspin OS=Bos taurus OX=9913 GN=CLSPN PE=4 SV=2 CANONICAL=A0A3Q1LF69-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LF69-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF69/entry", "sequence": { "sequence": "MGAWSHVESLLRIGANHRGRGLHSGWARKLERRCLAGDGGSGRVLTSKATGDLFRPEWRAEETGVMTGEVVSEVHLEINDSKLISQEETDSPSDSGQGSCETIGPLSEQDSDEEIFVSRKLKSRKVLQESDSEREDPVSPEKTTYDAAEEEDKENLCAEKNGEARRIHKTLADSDESDVEESLCQENSETQMTPCLEMGLQSENSVDFTVDRKISKKPLCGKEGIGGKAKVKSKRRLEKEERKMEKIRQLKKKETKNEEDDVKQPFNDSGCLLVDKDLFETGLEEEDHSPLEDEESLESIRAAVKNKVKKHKKKELSLESGVYSFEEETELSKGTTRKERKAAKLSKEELKKLHSETQRLIRESALNLPYHMPENKTVHEFFKRKPRPTCQGNAMALLKSTKYQASHHKETIDTENSTEVNGDHHSKDSAQTTGAGCEMEINALPAVSKEPQITAKSDEPCGKDLTGSEELEVPEKQEQSDARPPPGDVSVARQECSVLGNKDSEEHQTEGLVAPEPHALEEEKGLRKTEAADEKAEEPSQQNGSTAAVPPEKARRFTVDRLRQLGVDVFRKPQLGADRDSFVILEEPETNRELEALKQRFWKHANPTARPRAGQKVNVNIIVKDVGADGKEELKADVVPMTLAAEKLDGASHTKPGEKLQVLKAKLQEAMKLRRLEERQKRQALLKLDNEDGFEEEEEEEEEEEEMTDDSEEDGEEEGEEALEEEEEKEEGAEEEGNEETAEFLLGGEEIETKDEKEIDKENDDGSGEIGKSVGLSVPKPLSSDSTFLLFKDSSSKMGYSPSEEKSEIDENSGKRPSKLDEDDSCSLLTKESSHNSSFELIGSTLPSYQPCNRQTGRGTSLFPTAGGFRSPSPGLFRASLVSSASKSSGKLSEPSLPIEDSQDLYNASPEPKTLFLGAGDFQFCLEDDTQSQLLDADGFLNVRNHRNQYQDLKPRLPLASMDENAMDANMDELLDLCTGKFASQAEKPLPGKSDKKENMEELLDLCSGKFTSQDASTLDPSELNKQEKESSLGDPMEEALALCSGSFPTDREEEGEEEEFGDFRLVPNDNEFDSDEDEHSESDKEDLTPEDREDDDEEDLLQQSEKSKRQMRLKKYLEDEAEVSGSDMGSEDEYDGEELDEYEEDVIDEVLPSDEELQSQVKKIHMKTMLDDDKRELRLYQERYLADGDLHSDGPGRMRRFRWKNIDDASQMDLFHRDSDDDQIEEQLDETEARWRKERIEREQWLRDHAQQGKIAAEDEEEIGEDSQFMMLAKKVTAKALQKNVSHTVVIQESKSLFRNPFEAIKPGSDNQLKTGSLLNQPKAVLQKLAALSDLNPSAPRNSRNFVFHTLSPVKAEAAKESSKPRVRRRGPSLMTSTSPKRLKIDDSTSESKQSIFRYLES", "length": 1403, "header": "tr|A0A3Q1LF69-1|A0A3Q1LF69_BOVIN Isoform 1 of Claspin OS=Bos taurus OX=9913 GN=CLSPN PE=4 SV=2 CANONICAL=A0A3Q1LF69-1" }, "locus": { "chromosome": "3", "start_pos": 110047340, "end_pos": 110020808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074281.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074281.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056728.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056728.2" } ] } }, { "isoform_ac": "A0A3Q1M4G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4G6/entry", "sequence": { "sequence": "MTGEVVSEVHLEINDSKLISQEETDSPSDSGQGSCETIGPLSEQDSDEEIFVSRKLKSRKVLQESDSEREDPVSPEKTTYDAAEEEDKENLCAEKNGEARRIHKTLADSDESDVEESLCQENSETQMTPCLEMGLQSENSVDFTVDRKISKKPLCGKEGIGGKAKVKSKRRLEKEERKMEKIRQLKKKETKNEEDDVKQPFNDSGCLLVDKDLFETGLEEEDHSPLEDEESLESIRAAVKNKVKKHKKKELSLESGVYSFEEETELSKGTTRKERKAAKLSKEELKKLHSETQRLIRESALNLPYHMPENKTVHEFFKRKPRPTCQGNAMALLKSTKYQASHHKETIDTENSTEVNGDHHSKDSAQTTGAGCEMEINALPAVSKEPQITAKSDEPCGKDLTGSEELEVPEKQEQSDARPPPGDVSVARQECSVLGNKDSEEHQTEGLVAPEPHALEEEKGLRKTEAADEKAEEPSQQNGSTAAVPPEKARRFTVDRLRQLGVDVFRKPQLGADRDSFVILEEPETNRGEKLQVLKAKLQEAMKLRRLEERQKRQALLKLDNEDGFEEEEEEEEEEEEMTDDSEEDGEEEGEEALEEEEEKEEGAEEEGNEETAEFLLGGEEIETKDEKEIDKENDDGSGEIGKSVGLSVPKPLSSDSTFLLFKDSSSKMGYSPSEEKSEIDENSGKRPSKLDEDDSCSLLTKESSHNSSFELIGSTLPSYQPCNRQTGRGTSLFPTAGGFRSPSPGLFRASLVSSASKSSGKLSEPSLPIEDSQDLYNASPEPKTLFLGAGDFQFCLEDDTQSQLLDADGFLNVRNHRNQYQDLKPRLPLASMDENAMDANMDELLDLCTGKFASQAEKPLPGKSDKKENMEELLDLCSGKFTSQDASTLDPSELNKQEKESSLGDPMEEALALCSGSFPTDREEEGEEEEFGDFRLVPNDNEFDSDEDEHSESDKEDLTPEDREDDDEEDLLQQSEKSKRQMRLKKYLEDEAEVSGSDMGSEDEYDGEELDEYEEDVIDEVLPSDEELQSQVKKIHMKTMLDDDKRELRLYQERYLADGDLHSDGPGRMRRFRWKNIDDASQMDLFHRDSDDDQIEEQLDETEARWRKERIEREQWLRDHAQQGKIAAEDEEEIGEDSQFMMLAKKVTAKALQKNVSHTVVIQESKSLFRNPFEAIKPGSDNQLKTGSLLNQPKAVLQKLAALSDLNPSAPRNSRNFVFHTLSPVKAEAAKESSKPRVRRRGPSLMTSTSPKRLKIDDSTSESKQSIFRYLES", 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"end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LF99-1", "uniprot_ac": "A0A3Q1LF99", "uniprot_id": "A0A3Q1LF99_BOVIN", "mass": { "chemical_mass": 290468.0, "monoisotopic_mass": 290468.0 }, "refseq": { "ac": "XP_005218836", "name": "ankyrin repeat domain-containing protein 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218836" }, "gene_names": [ { "name": "ANKRD11", "type": "recommended", "evidence": [ { "id": "A0A3Q1LF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ] }, { "name": "ANKRD11", "type": "synonym", "evidence": [ { "id": "XP_005218836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218836" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 11", "type": "recommended", "evidence": [ { "id": "A0A3Q1LF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005218836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218836" } ] } ], "function": [ { "annotation": "Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells. May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. Has a role in proliferation and development of cortical neural precursors. May also regulate bone homeostasis.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99#function" }, { "database": "UniProtKB", "id": "ARBA00059495", "url": "https://www.uniprot.org/uniprotkb/ARBA00059495#function" }, { "database": "UniProtKB", "id": "E1BAT5", "url": "https://www.uniprot.org/uniprotkb/E1BAT5#function" }, { "database": "UniProtKB", "id": "A0A3Q1MQ46", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQ46#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANKRD11", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99", "locus": { "chromosome": "18", "start_pos": 14326628, "end_pos": 14353990, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016006", "url": "https://www.ensembl.org/id/ENSBTAG00000016006" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016006", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016006", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532856", "url": "https://www.ncbi.nlm.nih.gov/gene/532856", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532856", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532856", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ADQHSKH", "url": "https://omabrowser.org/oma/group/ADQHSKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LF99", "url": "https://www.orthodb.org/?gene=A0A3Q1LF99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MQ46", "url": "https://www.orthodb.org/?gene=A0A3Q1MQ46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BAT5", "url": "https://www.orthodb.org/?gene=E1BAT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24145:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24145:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005218836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LF99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M904", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M904", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M904-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M904-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQ46", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQ46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZF5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZF5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAT5", "url": "https://www.uniprot.org/uniprotkb/E1BAT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BAT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKGGCSRTPQQEERSLSSDMVEKQPGKKDKDKVSLTKTPKLDRSDGGKEVRERAPKRKLPFTVGANGEQKDSDTEKQGPERKRIRKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDMTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVASSPTMVNLLLGKGTYTSSEESSAESSEEEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKTVTPVKDEYEFDEDDEQDRTPPVDDKHLLKKDYRREAKSNSFISIPKMEVKSYTKNSTIAPKKASHRILSDTSDEEDVGVAVGAGEKLRLSAHTMLPGNKTREPSNCKQQKERNKVKKKRKKEIKGKEVRFGKRGDTFCSSESESESSESGEDGGDSAGSPGCLKESPLVLKDPALFSSLSASSTSSHGSSTAQKHNTGHADPHAKHWRTDNWKTISSPAWSEVSSLSDSTRTRLSSESDGSSEGSSVESLKPVRKRQEHKKRAGLQGTLPDRKNSFHPSGDGAIPKLDKEGKVVKKHKTKHKHKSKEKGLCSVSQELKLKSFTYEYEDSKQRADKAILLDDVPAENKLKGLKHERDHCKKEEKLSKMKSEEKDWLFKDEMIKVSREEKSLKRIRDLNKDGGRAFREEKDRSNKAEKERLLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDFKEEKIPKEKEKIFKEDKEKLRKEKGYREDSAFDEYCNKSQFLENEDTKFSLSDDQQDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVARLILETVKEDSKEKRRESKAREKRGDRDIFSRKKDRDSLERRREHVADRHRVVPSFLCEKDKRRRESTEGSRDRKEAPEAAKERRDGRVKPEEAHREDLKEYGCDFGKSLEPWERHHPGREKKEKLKLEKHKEKSSDKDKSEKLILEKCQRDREFDKCFKEKKDAKEKHKDVHSKDKERKASLDQGRDKREKAFPGVLSEDFSEKKDEKKGKEKSWYIADIFTDESEDEKDDYTASGFKIGEASEGRGDGPPEREDGRELHPPDRHRKHSADRQAHAEKQKDKEMREKKKEKGAVDGGKDRREKTFEKHKEKKDRKDRTSVDSVQDKRSKQKPPEKGEKRPPAEDKAKTRHRERPDREQGRERKASKGAEVEKSLLERLEEEALQDFREDSNDKASEASSDGFPDRGQDPSLSALLDVSFPEPPEERVRERERHRHASSSSKKSHDRERGKKDKLEKKDKSDDYKDAGSRKDASQYEKELLDSDAYGASYGSKADAEDELDKALELFSTEKKEKNDPEREPPKKVEKELRPYGSSALSLLKEKRRREKHRERWREDKERHRHHREEPKPPARDTAPGAFRDKAKDEGGKLGEARLKEKIKENPEKEKGDPTKLSNGNDKLLPTRDPGKKDVRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMRQMEKLRHRSGDPKLKEKARPAEDARKKSLDGPPKKPPGPDLTPKDRKPKESAPPAPATENKPHPGLAVDPRDWLAGPHMKEVLPASPRPDHGRPTGVPTPASVVSCPSYEEAMHTPRTPSCSADDYPDLMFDCTDPQPMSSTSASACSPSFFDRFSVATSGISETPGQTPTRPLCTNLYRSVSVDVRRTPEEEFGLGDKLFRQQSVPAAPSYGSPGQHPEDKAPGPPAPAEKFTCLSPGYYSPDYGMPSPKVDALHCPPAATVNLTPSPEGAFAGLQAKSPPSHRDELLAPSMEGALPPDLGIPLDATEDQQATAAIIPPEPSFLEPLDEGPFSTVITEEPVEWAHPAAAEQGLPPGLIGGAPGDTAGWPVGSDLLLKSPQRFPESPKHFCPAESLHPEPPYPGSPVSYPLPVPEPGLEAKDKAEGAVPAAVSASEESAPFAPPSRLESFFSNCKSLPDAPPDAPPEPACVTAVAQVEALGPLENNFLEGGHNLSALGQVEPVPWPGAFPAAEDDLDLGPFSLPELPLQTKDVPDVEAEPVEESPLVPPENTPLGAPVLPGGGEAAGTAADQQLVSPSDQAAARLPTEAAPEPLEEPKPAALPEATAETGSGPDGRAPEDSHPGSGLTPALSEQRPPGSGDEEAEGQDLSASPHSTPDAPVDGSAQTHVADGAGPQDSAGLEGPLDSVQPESTEPEPKVTAEAPKAPKVEEIPQRMTRTRAQMLANQHKQSSPPTEKEPTPTPTPRAKGRGSEDDDPQAQHPRKRRFQRSSQQLAQQMHTSTRQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYISPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2599, "header": "tr|A0A3Q1LF99-1|A0A3Q1LF99_BOVIN Isoform 1 of Ankyrin repeat domain-containing protein 11 OS=Bos taurus OX=9913 GN=ANKRD11 PE=4 SV=2 CANONICAL=A0A3Q1LF99-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LF99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99/entry", "sequence": { "sequence": "MPKGGCSRTPQQEERSLSSDMVEKQPGKKDKDKVSLTKTPKLDRSDGGKEVRERAPKRKLPFTVGANGEQKDSDTEKQGPERKRIRKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDMTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVASSPTMVNLLLGKGTYTSSEESSAESSEEEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKTVTPVKDEYEFDEDDEQDRTPPVDDKHLLKKDYRREAKSNSFISIPKMEVKSYTKNSTIAPKKASHRILSDTSDEEDVGVAVGAGEKLRLSAHTMLPGNKTREPSNCKQQKERNKVKKKRKKEIKGKEVRFGKRGDTFCSSESESESSESGEDGGDSAGSPGCLKESPLVLKDPALFSSLSASSTSSHGSSTAQKHNTGHADPHAKHWRTDNWKTISSPAWSEVSSLSDSTRTRLSSESDGSSEGSSVESLKPVRKRQEHKKRAGLQGTLPDRKNSFHPSGDGAIPKLDKEGKVVKKHKTKHKHKSKEKGLCSVSQELKLKSFTYEYEDSKQRADKAILLDDVPAENKLKGLKHERDHCKKEEKLSKMKSEEKDWLFKDEMIKVSREEKSLKRIRDLNKDGGRAFREEKDRSNKAEKERLLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDFKEEKIPKEKEKIFKEDKEKLRKEKGYREDSAFDEYCNKSQFLENEDTKFSLSDDQQDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVARLILETVKEDSKEKRRESKAREKRGDRDIFSRKKDRDSLERRREHVADRHRVVPSFLCEKDKRRRESTEGSRDRKEAPEAAKERRDGRVKPEEAHREDLKEYGCDFGKSLEPWERHHPGREKKEKLKLEKHKEKSSDKDKSEKLILEKCQRDREFDKCFKEKKDAKEKHKDVHSKDKERKASLDQGRDKREKAFPGVLSEDFSEKKDEKKGKEKSWYIADIFTDESEDEKDDYTASGFKIGEASEGRGDGPPEREDGRELHPPDRHRKHSADRQAHAEKQKDKEMREKKKEKGAVDGGKDRREKTFEKHKEKKDRKDRTSVDSVQDKRSKQKPPEKGEKRPPAEDKAKTRHRERPDREQGRERKASKGAEVEKSLLERLEEEALQDFREDSNDKASEASSDGFPDRGQDPSLSALLDVSFPEPPEERVRERERHRHASSSSKKSHDRERGKKDKLEKKDKSDDYKDAGSRKDASQYEKELLDSDAYGASYGSKADAEDELDKALELFSTEKKEKNDPEREPPKKVEKELRPYGSSALSLLKEKRRREKHRERWREDKERHRHHREEPKPPARDTAPGAFRDKAKDEGGKLGEARLKEKIKENPEKEKGDPTKLSNGNDKLLPTRDPGKKDVRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMRQMEKLRHRSGDPKLKEKARPAEDARKKSLDGPPKKPPGPDLTPKDRKPKESAPPAPATENKPHPGLAVDPRDWLAGPHMKEVLPASPRPDHGRPTGVPTPASVVSCPSYEEAMHTPRTPSCSADDYPDLMFDCTDPQPMSSTSASACSPSFFDRFSVATSGISETPGQTPTRPLCTNLYRSVSVDVRRTPEEEFGLGDKLFRQQSVPAAPSYGSPGQHPEDKAPGPPAPAEKFTCLSPGYYSPDYGMPSPKVDALHCPPAATVNLTPSPEGAFAGLQAKSPPSHRDELLAPSMEGALPPDLGIPLDATEDQQATAAIIPPEPSFLEPLDEGPFSTVITEEPVEWAHPAAAEQGLPPGLIGGAPGDTAGWPVGSDLLLKSPQRFPESPKHFCPAESLHPEPPYPGSPVSYPLPVPEPGLEAKDKAEGAVPAAVSASEESAPFAPPSRLESFFSNCKSLPDAPPDAPPEPACVTAVAQVEALGPLENNFLEGGHNLSALGQVEPVPWPGAFPAAEDDLDLGPFSLPELPLQTKDVPDVEAEPVEESPLVPPENTPLGAPVLPGGGEAAGTAADQQLVSPSDQAAARLPTEAAPEPLEEPKPAALPEATAETGSGPDGRAPEDSHPGSGLTPALSEQRPPGSGDEEAEGQDLSASPHSTPDAPVDGSAQTHVADGAGPQDSAGLEGPLDSVQPESTEPEPKVTAEAPKAPKVEEIPQRMTRTRAQMLANQHKQSSPPTEKEPTPTPTPRAKGRGSEDDDPQAQHPRKRRFQRSSQQLAQQMHTSTRQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYISPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2599, "header": "tr|A0A3Q1LF99-1|A0A3Q1LF99_BOVIN Isoform 1 of Ankyrin repeat domain-containing protein 11 OS=Bos taurus OX=9913 GN=ANKRD11 PE=4 SV=2 CANONICAL=A0A3Q1LF99-1" }, "locus": { "chromosome": "18", "start_pos": 14353960, "end_pos": 14327632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076630.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076630.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056796.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056796.2" } ] } }, { "isoform_ac": "A0A3Q1M904-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M904/entry", "sequence": { "sequence": "MPKGGCSRTPQQEERSLSSDMVEKQPGKKDKDKVSLTKTPKLDRSDGGKEVRERAPKRKLPFTVGANGEQKDSDTEKQGPERKRIRKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDMTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 421, "header": "tr|A0A3Q1M904-1|A0A3Q1LF99_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 11 OS=Bos taurus OX=9913 GN=ANKRD11 PE=4 SV=1 CANONICAL=A0A3Q1LF99-1" }, "locus": { "chromosome": "18", "start_pos": 14353960, "end_pos": 14327632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083801.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083801.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066605.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066605.2" } ] } }, { "isoform_ac": "A0A3Q1MQ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQ46/entry", "sequence": { "sequence": "MPKGGCSRTPQQEERSLSSDMVEKQPGKKDKDKVSLTKTPKLDRSDGGKEVRERAPKRKLPFTVGANGEQKDSDTEKQGPERKRIRKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDMTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVASSPTMVNLLLGKGTYTSSEESSAESSEEEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKTVTPVKDEYEFDEDDEQDRTPPVDDKHLLKKDYRREAKSNSFISIPKMEVKSYTKNSTIAPKKASHRILSDTSDEEDVGVAVGAGEKLRLSAHTMLPGNKTREPSNCKQQKERNKVKKKRKKEIKGKEVRFGKRGDTFCSSESESESSESGEDGGDSAGSPGCLKESPLVLKDPALFSSLSASSTSSHGSSTAQKHNTGHADPHAKHWRTDNWKTISSPAWSEVSSLSDSTRTRLSSESDGSSEGSSVESLKPVRKRQEHKKRAGLQGTLPDRKNSFHPSGDGAIPKLDKEGKVVKKHKTKHKHKSKEKGLCSVSQELKLKSFTYEYEDSKQRADKAILLDDVPAENKLKGLKHERDHCKKEEKLSKMKSEEKDWLFKDEMIKVSREEKSLKRIRDLNKDGGRAFREEKDRSNKAEKERLLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDFKEEKIPKEKEKIFKEDKEKLRKEKGYREDSAFDEYCNKSQFLENEDTKFSLSDDQQDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVARLILETVKEDSKEKRRESKAREKRGDRDIFSRKKDRDSLERRREHVADRHRVVPSFLCEKDKRRRESTEGSRDRKEAPEAAKERRDGRVKPEEAHREDLKEYGCDFGKSLEPWERHHPGREKKEKLKLEKHKEKSSDKDKSEKLILEKCQRDREFDKCFKEKKDAKEKHKDVHSKDKERKASLDQGRDKREKAFPGVLSEDFSEKKDEKKGKEKSWYIADIFTDESEDEKDDYTASGFKIGEASEGRGDGPPEREDGRELHPPDRHRKHSADRQAHAEKQKDKEMREKKKEKGAVDGGKDRREKTFEKHKEKKDRKDRTSVDSVQDKRSKQKPPEKGEKRPPAEDKAKTRHRERPDREQGRERKASKGAEVEKSLLERLEEEALQDFREDSNDKASEASSDGFPDRGQDPSLSALLDVSFPEPPEERVRERERHRHASSSSKKSHDRERGKKDKLEKKDKSDDYKDAGSRKDASQYEKELLDSDAYGASYGSKADAEDELDKALELFSTEKKEKNDPEREPPKKVEKELRPYGSSALSLLKEKRRREKHRERWREDKERHRHHREEPKPPARDTAPGAFRDKAKDEGGKLGEARLKEKIKENPEKEKGDPTKLSNGNDKLLPTRDPGKKDVRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMRQMEKLRHRSGDPKLKEKARPAEDARKKSLDGPPKKPPGPDLTPKDRKPKESAPPAPATENKPHPGLAVDPRDWLAGPHMKEVLPASPRPDHGRPTGVPTPASVVSCPSYEEAMHTPRTPSCSADDYPDLMFDCTDPQPMSSTSASACSPSFFDRFSVATSGISETPGQTPTRPLCTNLYRSVSVDVRRTPEEEFGLGDKLFRQQSVPAAPSYGSPGQHPEDKAPGPPAPAEKFTCLSPGYYSPDYGMPSPKVDALHCPPAATVNLTPSPEGAFAGLQAKSPPSHRDELLAPSMEGALPPDLGIPLDATEDQQATAAIIPPEPSFLEPLDEGPFSTVITEEPVEWAHPAAAEQGLPPGLIGGAPGDTAGWPVGSDLLLKSPQRFPESPKHFCPAESLHPEPPYPGSPVSYPLPVPEPGLEAKDKAEGAVPAAVSASEESAPFAPPSRLESFFSNCKSLPDAPPDAPPEPACVTAVAQVEALGPLENNFLEGGHNLSALGQVEPVPWPGAFPAAEDDLDLGPFSLPELPLQTKDVPDVEAEPVEESPLVPPENTPLGAPVLPGGGEAAGTAADQQLVSPSDQAAARLPTEAAPEPLEEPKPAALPEATAETGSGPDGRAPEDSHPGSGLTPALSEQRPPGSGDEEAEGQDLSASPHSTPDAPVDGSAQTHVADGAGPQDSAGLEGPLDSVQPESTEPEPKVTAEAPKAPKVEEIPQRMTRTRAQMLANQHKQSSPPTEKEPTPTPTPRAKGRGSEDDDPQAQHPRKRRFQRSSQQLAQQMHTSTRQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYISPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKVCGEQLLSPAGGQTSVGPHLDPPQRSQHPPAALPWMC", "length": 2575, "header": "tr|A0A3Q1MQ46-1|A0A3Q1LF99_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 11 OS=Bos taurus OX=9913 GN=ANKRD11 PE=4 SV=1 CANONICAL=A0A3Q1LF99-1" }, "locus": { "chromosome": "18", "start_pos": 14353960, "end_pos": 14329385, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085664.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085664.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074091.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074091.1" } ] } }, { "isoform_ac": "A0AAA9RZF5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZF5/entry", "sequence": { "sequence": "MPKGGCSRTPQQEERSLSSDMVEKQPGKKDKDKVSLTKTPKLDRSDGGKEVRERAPKRKLPFTVGANGEQKDSDTEKQGPERKRIRKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDMTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVGASTDPRVGLL", "length": 260, "header": "tr|A0AAA9RZF5-1|A0A3Q1LF99_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 11 OS=Bos taurus OX=9913 GN=ANKRD11 PE=4 SV=1 CANONICAL=A0A3Q1LF99-1" }, "locus": { "chromosome": "18", "start_pos": 14353960, "end_pos": 14341818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093913.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093913.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078974.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078974.1" } ] } }, { "isoform_ac": "E1BAT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BAT5/entry", "sequence": { "sequence": "MENRRTRTQMPPAQSTPWYCKAGSLLEAPWHEMEAPRSKKKEKQGPERKRIRKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDMTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVASSPTMVNLLLGKGTYTSSEESSAESSEEEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKTVTPVKDEYEFDEDDEQDRTPPVDDKHLLKKDYRREAKSNSFISIPKMEVKSYTKNSTIAPKKASHRILSDTSDEEDVGVAVGAGEKLRLSAHTMLPGNKTREPSNCKQQKERNKVKKKRKKEIKGKEVRFGKRGDTFCSSESESESSESGEDGGDSAGSPGCLKESPLVLKDPALFSSLSASSTSSHGSSTAQKHNTGHADPHAKHWRTDNWKTISSPAWSEVSSLSDSTRTRLSSESDGSSEGSSVESLKPVRKRQEHKKRAGLQGTLPDRKNSFHPSGDGAIPKLDKEGKVVKKHKTKHKHKSKEKGLCSVSQELKLKSFTYEYEDSKQRADKAILLDDVPAENKLKGLKHERDHCKKEEKLSKMKSEEKDWLFKDEMIKVSREEKSLKRIRDLNKDGGRAFREEKDRSNKAEKERLLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDFKEEKIPKEKEKIFKEDKEKLRKEKGYREDSAFDEYCNKSQFLENEDTKFSLSDDQQDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVARLILETVKEDSKEKRRESKAREKRGDRDIFSRKKDRDSLERRREHVADRHRVVPSFLCEKDKRRRESTEGSRDRKEAPEAAKERRDGRVKPEEAHREDLKEYGCDFGKSLEPWERHHPGREKKEKLKLEKHKEKSSDKDKSEKLILEKCQRDREFDKCFKEKKDAKEKHKDVHSKDKERKASLDQGRDKREKAFPGVLSEDFSEKKDEKKGKEKSWYIADIFTDESEDEKDDYTASGFKIGEASEGRGDGPPEREDGRELHPPDRHRKHSADRQAHAEKQKDKEMREKKKEKGAVDGGKDRREKTFEKHKEKKDRKDRTSVDSVQDKRSKQKPPEKGEKRPPAEDKAKTRHRERPDREQGRERKASKGAEVEKSLLERLEEEALQDFREDSNDKASEASSDGFPDRGQDPSLSALLDVSFPEPPEERVRERERHRHASSSSKKSHDRERGKKDKLEKKDKSDDYKDAGSRKDASQYEKELLDSDAYGASYGSKADAEDELDKALELFSTEKKEKNDPEREPPKKVEKELRPYGSSALSLLKEKRRREKHRERWREDKERHRHHREEPKPPARDTAPGAFRDKAKDEGGKLGEARLKEKIKENPEKEKGDPTKLSNGNDKLLPTRDPGKKDVRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMRQMEKLRHRSGDPKLKEKARPAEDARKKSLDGPPKKPPGPDLTPKDRKPKESAPPAPATENKPHPGLAVDPRDWLAGPHMKEVLPASPRPDHGRPTGVPTPASVVSCPSYEEAMHTPRTPSCSADDYPDLMFDCTDPQPMSSTSASACSPSFFDRFSVATSGISETPGQTPTRPLCTNLYRSVSVDVRRTPEEEFGLGDKLFRQQSVPAAPSYGSPGQHPEDKAPGPPAPAEKFTCLSPGYYSPDYGMPSPKVDALHCPPAATVNLTPSPEGAFAGLQAKSPPSHRDELLAPSMEGALPPDLGIPLDATEDQQATAAIIPPEPSFLEPLDEGPFSTVITEEPVEWAHPAAAEQGLPPGLIGGAPGDTAGWPVGSDLLLKSPQRFPESPKHFCPAESLHPEPPYPGSPVSYPLPVPEPGLEAKDKAEGAVPAAVSASEESAPFAPPSRLESFFSNCKSLPDAPPDAPPEPACVTAVAQVEALGPLENNFLEGGHNLSALGQVEPVPWPGAFPAAEDDLDLGPFSLPELPLQTKDVPDVEAEPVEESPLVPPENTPLGAPVLPGGGEAAGTAADQQLVSPSDQAAARLPTEAAPEPLEEPKPAALPEATAETGSGPDGRAPEDSHPGSGLTPALSEQRPPGSGDEEAEGQDLSASPHSTPDAPVDGSAQTHVADGAGPQDSAGLEGPLDSVQPESTEPEPKVTAEAPKAPKVEEIPQRMTRTRAQMLANQHKQSSPPTEKEPTPTPTPRAKGRGSEDDDPQAQHPRKRRFQRSSQQLAQQMHTSTRQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYISPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2565, "header": "tr|E1BAT5-1|A0A3Q1LF99_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 11 OS=Bos taurus OX=9913 GN=ANKRD11 PE=4 SV=4 CANONICAL=A0A3Q1LF99-1" }, "locus": { "chromosome": "18", "start_pos": 14349538, "end_pos": 14327632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021306.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021306.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021306.7", "url": "https://www.ensembl.org/id/ENSBTAP00000021306.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1657, "start_aa": "Thr", "end_pos": 1657, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1657", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2300, "start_aa": "Thr", "end_pos": 2300, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2300", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2302, "start_aa": "Thr", "end_pos": 2302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2302", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:532856", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532856", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MFN7-1", "protein_name": "Ankyrin repeat domain-containing protein 11", "gene_name": "Ankrd11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPKGGCSKTPQQEDFSLSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVRERATKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVARKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYSKNNALAPKKAAHRILSDTSDEEDVSVAMGAGEKLRLSAHTMLPSSKARESSSSRQQKEKNKLKKKRKKETKGKEVRFGKRNDKFCSSGSESESSESDEDDGDSVGSSSCLKGSPLVLKDPSLFSSLSASSTSSHGSASAQKHSSGHSDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRKQEHRKRGGLQSMPPEKRSTFHPCTDGAVSKLDKEGKVVKKHKTKHKHKNKEKGQSSVSQELKLKSFTYEYEDSKQKSDKAILLDNDISTENKLKVLKHDRDHFKKEDKLGKIKSEDKEWLFKDEKALKRIKDMSKEINRSFREEKDRPSKVEREKSTKEKSPKEEKLRLYKEERKKRSKDRPSKLEKKNDMKELSKEKDKSFKEDKEKLKKEKLYREDATFDEYCNKSQFLEHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSPVTDYRDIKSDSVAKLILETVKDDSKEKKRDNRTREKRDFRDSFFRKKDRDYLDKNSEKRRDQTEKHKSIPSYLSEKDKKRRESADVVRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCESTFKDKSDCDFTKNLEPWERPHAAREKERKDVLEKERKEKGRAEKYKDKSSERDRSEKSILEKCQKDKEFEKCFKEKKDGKEKHKDIHSKDRKASLDQMREKKEKMFPSIISEDFSEKKDDKKGKEKSWYIADIFTDESEDEKDDYVTSSFKVGEASDTQRVDSLQDKEDGREHPSDRHRKSSSDRQHTEKPRDKEPKEKKKDRGVAEGGKDKKEKIFEKHKEKKEKECAEKYKDRKDRASIDSAQEKKNKQKVPEKVEKKHFAEDKAKSKHKEKPEKEHSRERKSSRGPEVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPPEDKTRENTCLSEKLREKERHRHSSSSSKKSHERERAKKEKAEKKEKSEDYKDNSSGIRKDSSQYEKDFLDTEAYGVSYTTKADIEEELDKAIELFSSEKKDRNDSEREPAKKIEKELKPYGSSTISILKEKKKREKHREKWRDEKEKHRDKHVDGFLRHHKDEPKPTAKDKDNPPNSFKEKSRDESLKLSETKLKEKFKENTEREKGDLVKMSNGNDKLLPSRDSSKKDIRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEKKPTDDGRKKSLDLPSKKALGLDPPFKDKKLKESATTLPTGESKPHTGPGTESKDWLAGQPLKEVLSASPRTEQGRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTSACSPPFFDRFSVASSVVSENPGQTPTRPVSTNLYRSISVDIRRTPEEEFSVGDKLFRQQSVPAASFDSPVQHLLEEKTPLPPVPAEKFACLSPGYYSPDYGIPSPKVDTLHCPPTAVVNATPPPDSVFSSLPAKSSPSPRGELVTPAIEGTLPPDLGLPLDATEDQQATAAILPPEPSYLEPLDEGPFNTVITEEPVEWAHTTAEQALSSTLIASASENPVSWPVGSELLLKSPQRFAESPKHFCPGESLHSTTPGPFSAAEPTYPVSPVSYPLPAPESGLEEVKDGGTGAIPVAISAAEGAAPYAAPTRLESYFNNCKSIPDAPLDTAPETTCVTTVAQVEALGPLESSFLDSNHSMSALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAEAVEGSPVPPVESSPGPTGVLSSGEVTASATEEQPAPPPEEASPQCSTEPEPSEEPKLDVVLEATVETEVPADDSAPEASVSNLVSAPSPPEQHPLGGGDDETEVEDPSAAPCCASDGPTTDGLTQAHNNAEATCVVAAAEGPPGNIQPEATDTESKPSAEVPKAPKVEEVPQRMTRNRAQMLASQSKQNITPTEKDPMPAPTSRAKGRASEEEDAQAQHPRKRRFQRSSQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2649 }, "evidence": [ { "id": "A0A3Q1LF99", "url": "https://omabrowser.org/oma/group/A0A3Q1LF99/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6AA00-1", "protein_name": "Ankyrin repeat domain-containing protein 11", "gene_name": "Ankrd11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGGCSKTPQQEDCSLSNDMVEKQTGKKDKDKVSLTKTPKLDRTDGGKEVRERVTKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVPRKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRREAKSNSFISIPKMEVRSYSKNNTLAPKKAAHRILSDTSDEEDVSASIGAGEKLRLSAHTMLPSSKARESSSSRQQKEKNKLKKKRKKETKGKEVRFGKRSDKFCSSGSESESSESEEDDGDSVGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSAVAQKHSSGHTDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRKQEHRKRGSLQSMPERRGTFHPCADGAVPKLDKEGKVVKKHKTKHKHKHKEKGPCSVSQELKLKSFTYEYEDSKQKPDKAILLENDVSTENKLKVLKHDRDKLSKTKSEDKEWLFKDEKALKRMKDVSKDTSRAFREERDRPSKTERERSTKEKSPKEEKLRLYKEERKKKSKDRPFKLEKKNDMKEVSKEKEKAFREDKEKLKKEKLCRDDAAFDDYCNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSVTDYRDIKSDSVAKLILETVKEDSKEKKRDNKTREKRDFRDSFFRKRDRDCVDRNSEKRRDHTEKQRSFPSYLSEKDKKRRESAEGGRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCDSTFKDKSDCDFTKTLEPWERPHAAREKEKKDALEKDRKEKGRAEKYKDKSGERERNEKSILEKCQKDKEFEKCFKEKKDGKEKHKDTHSKDRKTPFDQLREKKEKAFSSLISEDFSERKDDRKGKEKSWYIADIFTDESEDEKEECVASSFKTGETGDSQRAESLQEKEDGREHPSDRHRKASSDRQHTEKPRDKEPKEKRKDRGAAEGGKDKKEKIFEKHKEKKDKECAEKYKERKDRASVDSAPEKKNKQKLPEKVEKKHFVEDKAKSKHKEKPEKDHSRERKSSRGPDVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPAEDKARESTCLSEKLKERERERHRHSSSSSKKSHERERAKKEKADKKEKGEDYKDGGGGRKDASQYEKDFADAEAFGGSYTTKADTEEDLDKAIELFSSEKKDRNDSEREPAKKLEKELKPYGSSTISILKEKKKREKHREKWREEKEKHRDKHIDGFLRHHKDEPKPAAKDKDNPPNCFKEKSREESLKLSEAKLKEKFKENAEREKGDSVKMSNGNDKPLPSRDANKKDSRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEKKPTDDGRKKSLDFPSKKALGLDKKVKEPAPVLPTGEGKPHSGPGTESKDWLAGQPLKEVLPASPRTEQGRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTSACSPPFFDRFSVASSVVAENAGQTPTRPISTNLYRSISVDIRRTPEEEFSVGDKLFRQQSVPAASSFDSPVQHLLEEKAPLPPVPAEKFACLSPEYYSPDYGIPSPKVDTLHCPPTAVVSATPPPDSVFSNLPPKSSPSPRGELLTPAIEGALPPDLGLPLDATEDQQATAAILPPEPSYLEPLDEGPFNTVITEEPVEWTHSAAEQSLPSSLIASASETPVSWPVGSELMLKSPQRFAESPKHFCPGEPLHSTTPGPFSAAEPTYPVSPGSYPLPAPEPALEEVKDGGTGAIPVAIAAAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPEPASVTTVAQVEALGPLESSFLDSSHSISALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEETKLDVVLEAAAETEVLADDSAPEASISNLVPAPSPPEQQRPAGGGDEETEAEDPSAAPCCAPDGPTTDGLAQAPNSAEAACVVAAVEGPPGNIQPEATDPEPKPTSEAPKAPKVEEVPQRMTRNRAQMLASQSKQGIPATEKDSMPAPASRAKGRAPEEEDAQAQHPRKRRFQRSGQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2639 }, "evidence": [ { "id": "A0A3Q1LF99", "url": "https://omabrowser.org/oma/group/A0A3Q1LF99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AUK7-1", "protein_name": "Ankyrin repeat domain-containing protein 11", "gene_name": "ankrd11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPKGGGSKTPQLEDFPLSTDMVEKQGGKKDKDKGSSNKTPKLDRSDGVKEMKEKAPKRKLPFTVGANGDQKDSDSEKQGPERKRIKKEPTNTRKSGLPFGMGMPGIRAGYPLSERQQVALLMQMTAEESVNSPDTTPKHQSQSSLGQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGEARRIKELINEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDASNNGHLKVVKLLLRYGGDPCQSNRRGETPLKVANSQTMLNLLLGKITYSSSEESSSADSSEEEDSPSFAPSSSVDGNNTDSEFEKGLKLKGKGMDPPKSTTTPVKDEYEFDEDDEEERVPPVDDKHLLKKEFRKEPVSKTNNLISIPKMEVKTYSKSNSLTPKKAVRRILSDSNSSDEDDRTLCFTPTTTPRQPAPQTNIKSRDSTSLNSKQQKEKSKVKKKRKKETKNNVNKEVRFNKVNKFCTSDSEIGDLESEDDKGSIQNTNCVKDSSTLSLKDPSVFTSLSVTSSSSHGSLNSQKHTQSLAEQHPKQWRTDGWKTVSSPTMSDVSSLSDSVRTRLSSESDYSSADSSVESVKQVKKKVQDSRKKNNTHVNAVDKKNSELYKTSNTEGAISKADKDGKVLKKHKVKHKHKSKEKDKAPSVVLSQDMNEKFVKSFSFDFDDTRQKSLIVETESPSENRVKLSKHEKDHFKKEDRLSKGKSEDKDWPVKETQRVVKEEKSKKTKESNKEKVNKEERDKPLKTEKERSIKDKAKEEKQKAHKDDKKKKSKDKSLKTDKKNEQKEEKHFKSEKSVKEEKEKSKRDKSIKEEPDYDDFDLKNHLLEDTKMSASDDPHDRWQSDMSSDSSLYGDDSWDTPVKEYKANNAVKLIVETVKEESRDRRKENKFKDKKTDHADKRPEKETASKKKDKDTSDKKTENKKDWTDKQKFNSGQTMEKEKKRKESAESVKEKKDKDSVDCGRDRKDSYEFTKERKDSKAKQESLRDDYGSEAFFKDKPESETTCKSDPRERNHSGKEREKKIDGVEKKDKSKGEKHKDKPKDRNLDQEKEKPEKNAIDRSLKEKDLERASKDKRDGVKEKHKDSHSKDKERKMSSEQSKDKKEKASLDKHADKEKDFLEFKKEERKPEKKEKTWYTIADIFTDESEDEDDNYNGGVAKLSDSLGLSDSHRKDSTPDIDEMDNFQTDKHKKYSEGKTHSIEKQKDKEHKDKKKEKAAFDAGKERKASMEKHKDKKDKDSTETKHKERKDRSSVDSNQEKKSKLKLLDKRDVSDEKSKNKYKDKTEHLKDRKLSKGSGENEKSLLEKLEEEAMNDYKDDSNDRNSEISLDSFTDRGHEPVLSNFYDSSNISIPDMSEERRESLSITNPQDRFKEKERHRHSSSSSSKKSHDKEKEKVKKEKSEKKDKSEEIRESYGRRESLPFDKEPMPLEADPYTFPYGSKVDGEDDLDKTLEFEKEMSKKDKTNSIMNSDKLKDKKKKEKHKEKIKEEKHKYSDGLGSFRHSKEEQKSGLKENTQISSIKEKSKEDCSKFDGKNKDRIKDIVDKDRTDSKSKVKDENDKFSQSKETIRKDNRPREKLLVDGDLRLTSFGKMLSLKDQEIEERHKRHKERMKQMEKLRHRSGDPKLKDKTKSNEELKKNRSELSKKTGSVDAALKEKKIKEIGLPTQMMSPDRKPQPIDSQNSKDWLAGHQMKESLPASPRPDQNRPTGVPTPTSVISCPSYEEVMQTPRTPSCSAEDYSDIMFDGLECHNSSATTMSMNACSPSFFDRFSNSSNTFQEGTCITPAKNMQLPLVSRSVTSDVRRPLDVEFKAEADKLLRQHVQEGTEFESSASQLSEDKMAADRLNCLSSCFSPTADMSPRPDLLQHERLQDEVSAVNSISDGNEYSGCVYNNYLMKPSTPVHRPDPQEPCLDIAAPPTPAPAALPPMDIDDLSEPHQSGPGLMPAHPVSVSDYLPPVVEEQEDEEEEEEEEEDNDDDDDFVEDPTESHHAPEESMQARNNPTYLLGIEESDKKAWLECSDRRDPDVLPITPAHPQDNYMENSCDQSLGWNSEALMKSPHESYREVEAAVSKISSPYSHSDCDLQHIPNVIPVTPPHSTYSRAYCPSQIPDSHYEDPKDTVEDLPSPGRPVAETLESESPQLENFFTDCKPTPEENQMDLELPCMIKDNRQESPTYPAEISMPVAPPVSEDPVVSWADPFSGAADEMDDMGPFSIPELPFQEKEMQDPDITAPEIAENKHSPTLTRPPVIETSENVEMINVDLSSLSKAPCSPTVVPHDESSQDLVPPVSKDDYTPQCELEPEPQNIPDVLPIKETISEERGGFEGMDINNDNLLATEEQDHEYRKKEINPDAMMPSVMVQYLELPVTTKPHLLGQNPVVALGPSCSPHLTVHIPAVSMPTSTHVSETLETTAKLSVTIPVSEAPKKIEEIPQRITRKKAQMLANQNKQSATLSSSSITHSVSSSPITTSVTTSCVTVEKEKETISSSNVQTSAPSAPALITKTKGRPIEDDDNQSQHPRKRKFPKSGQQQVQVQLVNTAMKQTREMIQQTLAVIVNAIKLDEIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYITPQAPQCYADYVTYTGSYLLDGKPLSKLHIPVIAPPPSLSEPLKELFRQQEAVRGKLRLQHSIEREKLIVSCEQEVLRVHCRAARTIANQAVPFSACTMLLDSEVYNMPSESQGDENKSVRDRFNARQFISWIQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2820 }, "evidence": [ { "id": "A0A3Q1LF99", "url": "https://omabrowser.org/oma/group/A0A3Q1LF99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Y377-1", "protein_name": "Ankyrin repeat domain-containing protein 11", "gene_name": "ANKRD11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPKGGCSKTPQPEDFSLSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVKERTTKRKLPFTVGTNGDQKDSDTEKQGPERKRIKKEPATRKPGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELIIEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHFKVVKLLLHYGGNPHQSNRKGETPLKVANSPTMVNLLLGKTTYPSSEESSTETSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKPKAQEPPKTITPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKANSFISIPKMEVKTYTKNNTITPKKAAHRILSDSSDEEETSVAVGTGEKLRLSTHSILPSSKIREPASTKAPKEKSKVKKKRKKETKSKEVRFGKKNDKFCSSESESENVESEEDDRDSLQSSSCVKDSRLVLKESSLFNSLSASSTSSHGSLGSQKHNANLTEQHSKHWRTDNWKTISSPAWSDVSSLSDSTRTRLTSESDYSSEESSLESLKPVRKKPEHKKKNTSHSTVSEKKNSFHSNVDGAIPKLDKEGKVVKKHKTKHKHKNKDKGQCPISQDIKIIKTFSFEFEDSKQKPEKGLIVETENPVENKLKVLKHEREHCKKEDKLPKGKAEEKDWLFKDETGKSSKEEKSLRKVKDGSKDMSKSFREGLSKSEKEKPVKEKSPKEEKPRIHKEERKKKSKDKQSKSEKKNELKEEKAAKLEKEKSFKEEKEKCKKEKMYREESGFDEFNNKAQFPESEDTKFSLSDDQQERWFSDLSSDSSFDFKGEDSWDSPVTDFREIKNDTVAKLIIEPVKEETKDKKKENKTKEKKEYSEKRSEKDSFLKKKERDYVEKSSEKKKDQTERHKAAPSYLPEKDKKRKDSAEGVKEKKEKDTGETNKDRKDSSDGSKDRKESKTKQEEPYRDEFKEYGCEAFFKEKSDTEFSGKALESWERHHSGKDKEKKDASEKEKKEKVKPEKYKEKSKEGDKEKNEKAAPEKIPKDKELEKSFKEKKESKEKYKDLHGKDKERKSSFDQVKEKKEKSFSTDREDFSEKKDEKKGKEKSWYSIADIFTDESEDERDDYSLTGFKVGESVGSEMHRLDSLQEKDEGEKELYSDKHRKYSSDRQHSGEKQKDKESKEKKKDKGTSEGGKEKKEKNSFEKHKEKKDKDSSEKYKDRKDRTSIDSNQEKKNKQKLPEKADKKHASDEKVKNKHKEKLDKEHSKEKKSSKGGEPEKSLLEKLEEEALNDYRDDSNDKISEISSDSFTDRGQDPGLSSLFESSNLSLADASEEKFKDSLPLPCLQDKLKEKERHRHSSSSSKKSHEKEKAKKEKTEKKEKTDEFKDSSSRKDSTHYEKDFSVDGEAFSSSYGMKAEPDEEPEKSIDYLFSEKKDKNDSERELSKKAEKEKTYGSSTISTAKEKKKRDKHKEKWKEEKEKHRDKHADGFFKHHKDEPKSALKDKDSPQVTAFKEKSKEENLKFGETKLKEKLKENQEKDKAESIKISNGNEKITLSKDSGKKDARPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKDKIKSSEDVRKRSLDLTAKKPLALDTQLKDKKLKELGPLTPILSPENKAQPAAGADSKDWITGPQLKEILPASPRPDQNRPTGVPTPASVVSCPSYEEVMQTPRTPSCSNEDYTDLMFECADSQHSLPISTMSMNACSPSFFDRYANVAGALPENPAQTPTRTIPSSNLYRSISVDIRRAPEEEFSVGDKFFRQQSVPATSNYDSPVQHLMEEKVPLPSVPAEKFQCLSPGYYSPDYGVSSPKVEALHCPPAAVSGVSQSPESVFSGLQAKSSPSHRDELLAPSVESALPPDLGMPLDTTEEQQATASIMPPEPTYLPPIEENNFGSAMPEQTSMDWDTPPARNPDTAIPPSLMANAAEHSVGWSMGSELLMKSPQQFAESPKPALCSLEPIHPTPVAFIPTDASYPVSPISYPLSVSEPGLDEVKEDAEEAVPGEMANAEEQAPYMSPTRLDTFFTGCKPLPEEAPEIPTETPCVPAEPQAEAVSVQENTYLENNSTTPANGEEAVTWPDSFTTPEDELDLGPFSLPELPLQPKDVAEAEVAEAEPAEEGMAAAPEVSAGSTKAGTAATATGEAEEPAAVPAAPVPPTDTEPPAEEQKPDGAVQEATSEATSGAEEKGAEEAEAQVLPAAPTEPAQAEGREVEGAQDEPAASAAVVEGSSGPPAAPSEGSAGPESTAGRTGSQGPSSQPEAPPAQAEVVEPVQKPVAEAPKPPKIEEIPQRITRNRAQMLANQNKQNAAAAEKEFPPVPAPTTRTKGRGTEEDDSQAQHPRKRRFQRSNQQLQQQINTSTQQTREMIQQTLAAIVDAIKLDDIEPYHSDRSNPYFEYLQIRKKIEEKRKILCYITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIERVRQRQQLLLGEKSPEFPLLRETEAALLTAVFALSQEKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLENQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2742 }, "evidence": [ { "id": "A0A3Q1LF99", "url": "https://omabrowser.org/oma/group/A0A3Q1LF99/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9Q4F7-1", "protein_name": "Ankyrin repeat domain-containing protein 11", "gene_name": "Ankrd11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKGGCSKTPQQEDFALSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVRERATKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVARKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKEAKANSFISIPKMEVKSYSKNNTLAPKKAAHRILSDTSDEEDVSVSIGAGEKLRLSAHTMLPGSKARESSSSRQQKEKNKLKKKRKKETKGKEVRFGKRSDKFCSSGSESESSESEEDDGDSVGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSAVAQKHGSGHTDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRKQEHRKRGVLQSAPSEKRSSFHPCTDGAVPKLDKEGKVVKKHKTKHKHKHKEKGQCSVSQELKLKSFTYEYEDSKQKSDKAILLESDLSTENKLKVLKHDREHLKKEDKLGRMKPEDKDWLFKDEKVLKRIKDANKDMSRAFREDKDRASKAERERATKDKSPKEEKLRLYKEERKKKSKDRASRLERKNDMKEDKLSKEKEKAFKEDKEKLKKEKLYREDAAFDDYCNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSVTDYRDIKNDSVAKLILETVKEDSKEKKRDNKIREKRDFKDSFFRKRDRDCLDKNSEKRRDQTEKHKSIPSYLSEKDKKRRESAEGGRDRRDGRIRSEEVHREDLKECGFESSFKDKSDCDFPKNLEPWERPHAAREKEKKDALEKERKEKGRADKYKEKSSERERSDKSTLDKCQKDKEFEKCFKEKKDGKEKHKDIHSKDRKASFDQLREKKEKVFSSIISEDFSERKDDRKGKEKSWYIADIFTDESEDEKDDCVAGSFKATEASDTQRVDGLPEKEEGREHPSDRHRKSSSDRQHTEKPRDKEPKEKKKDRGASEGGKDKKEKMEKIFEKHKEKKDKECAERYKDRKERASADSAPEKKNKQKLPEKVEKKHFAEDKVKSKHKEKPEKEHSRERERKPSRGPDVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPAEDKARDSACLSEKLREKERHRHSSSSSKKSHERERAKKEKAEKKEKSEDYKDSISSVRKDASQFEKDFLDAETYGVSYPTKADVEEELDKAIELFSSEKKDRSDPEREPAKRIEKELKPYGSSAISILKEKKKREKHRERWREEKERHRDKHVDGFLRHHKDEPKPAAKDKDNPPNSFKEKSREESLKLSETKLKEKFKENTEREKGDSIKMSNGNDKLVPSRDSGKKDSRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEKKPTEDGRKKSLDFPSKKALGLDKKVKEPAPTLTTGESKPHSGPGTESKDWLSGQPLKEVLPASPRTEQSRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTASTSACSPPFFDRFSVASSVVSENAAGQTPTRPISTNLYRSISVDIRRTPEEEFSAGDKLFRQQSVPAPSSFDSPVQHLLEEKAPLPPVPAEKFACLSPGYYSPDYGIPSPKVDTLHCPPTAVVSATPPPDSVFSNLPPKSSPSPRGELLSPAIEGTLPPDLGLPLDATEDQQATAAILPQEPSYLEPLDEGPFTTVITEEPVEWTHTAAEQGLSSSSLIASASENPVSWPVGSELMLKSPQRFAESPKHFCPGESLHSTTPGPYSAAEPTYPVSPGSYPLPAPEPALEEVKDGGTGAIPVAISAAEGAAPYAAPARLESFFSNCKSHPDAPLDTAPEPTGVTAVAQVEALGPLESSFLDSNPSISTLSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAEAAKASPVPPAESPPGPTGVLGGGDVPAPAAEEPPAPPPQEASPQLSTEPEPSEEPKLDVVLEATVETEVLADDSAPEASISNSVPAPSPPQQQPPGGGDEEAETEDPSATPCCAPDGPTTDGLAQAHNSAEASCVVAAAEGPPGNVQAEATDPEPKPTSEVPKAPKVEEVPQRMTRNRAQMLASQSKQGIPAAEKDPMPTPASRAKGRASEEEDAQAQHPRKRRFQRSSQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2643 }, "evidence": [ { "id": "A0A3Q1LF99", "url": "https://omabrowser.org/oma/group/A0A3Q1LF99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UB99-1", "protein_name": "Ankyrin repeat domain-containing protein 11", "gene_name": "ANKRD11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKGGCPKAPQQEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKLPFTAGANGEQKDSDTEKQGPERKRIKKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKLKEKAKPADDGRKKGLDIPAKKPPGLDPPFKDKKLKESTPIPPAAENKLHPASGADSKDWLAGPHMKEVLPASPRPDQSRPTGVPTPTSVLSCPSYEEVMHTPRTPSCSADDYADLVFDCADSQHSTPVPTAPTSACSPSFFDRFSVASSGLSENASQAPARPLSTNLYRSVSVDIRRTPEEEFSVGDKLFRQQSVPAASSYDSPMPPSMEDRAPLPPVPAEKFACLSPGYYSPDYGLPSPKVDALHCPPAAVVTVTPSPEGVFSSLQAKPSPSPRAELLVPSLEGALPPDLDTSEDQQATAAIIPPEPSYLEPLDEGPFSAVITEEPVEWAHPSEQALASSLIGGTSENPVSWPVGSDLLLKSPQRFPESPKRFCPADPLHSAAPGPFSASEAPYPAPPASPAPYALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPSGLESFFSNCKSLPEAPLDVAPEPACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVPWADAFAGPEDDLDLGPFSLPELPLQTKDAADGEAEPVEESLAPPEEMPPGAPGVINGGDVSTVVAEEPPALPPDQASTRLPAELEPEPSGEPKLDVALEAAVEAETVPEERARGDPDSSVEPAPVPPEQRPLGSGDQGAEAEGPPAASLCAPDGPAPNTVAQAQAADGAGPEDDTEASRAAAPAEGPPGGIQPEAAEPKPTAEAPKAPRVEEIPQRMTRNRAQMLANQSKQGPPPSEKECAPTPAPVTRAKARGSEDDDAQAQHPRKRRFQRSTQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRANPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFRQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2663 }, "evidence": [ { "id": "A0A3Q1LF99", "url": "https://omabrowser.org/oma/group/A0A3Q1LF99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "head morphogenesis", "id": "GO:0060323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060323", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "pmid": "" }, { "name": "face development", "id": "GO:0060324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060324", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "pmid": "" }, { "name": "skeletal system morphogenesis", "id": "GO:0048705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048705", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LF99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LF99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1822, "end_pos": 1824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2051, "end_pos": 2053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2511, "end_pos": 2513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 832, "end_pos": 834, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1657, 2300, 2302 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1822, "end_pos": 1824 }, { "start_pos": 2051, "end_pos": 2053 }, { "start_pos": 2511, "end_pos": 2513 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 832, "end_pos": 834 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 1333 }, { "field": "total_sites", "count": 1067 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 31 }, { "field": "total_sites", "count": 26 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 89 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LFH8-1", "uniprot_ac": "A0A3Q1LFH8", "uniprot_id": "A0A3Q1LFH8_BOVIN", "mass": { "chemical_mass": 36305.0, "monoisotopic_mass": 36305.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFH8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFH8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFH8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFH8", "locus": {} } ], "crossref": [ { "id": "A0A3Q1LFH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LFH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05740", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05740", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05774", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05774", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LFH8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPSGPASRRHVPWNRLLLAVSLLTFWTPPTTAQPTIETMPPLAAEGSDVLLLAHNVAKNPLGYAWYRGERVDNSQLIASYRVDTNATTKGPAHSGRETLYPNGTLLIQSVTQEDTGSYTLLVTNDDLRTERQTGHLHVHPVLPTPVITSNNSNPWEHKDTVVLTCGPETQNTSYMWWISNQSLPKSTRLKLSEDKRTLTVFNVTRKEKGPYVCETRNLVSISHSDPFTLDVLWRKNAQALSVGAITGIVIGVLLVLTLLAVLGCFIFLHSCVHNRGNWPPASTSGGGPSGSSVSQASLPDARPPAPIYQELLHPDTDVYCNISHKADVGP", "length": 332, "header": "tr|A0A3Q1LFH8-1|A0A3Q1LFH8_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0A3Q1LFH8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFH8/entry", "sequence": { "sequence": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFT5" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFT5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFT5" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFT5" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": 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"ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] } ] }, { "uniprot_ac": "A0AAA9S306", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] } ] }, { "uniprot_ac": "A0AAA9S5W8", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] } ] }, { "uniprot_ac": "A0AAA9SGM6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] } ] }, { "uniprot_ac": "A0AAA9SLN0", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] } ] }, { "uniprot_ac": "A0AAA9SV95", "gene_name": "RAB34", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV95" } ] } ] }, { "uniprot_ac": "A0AAA9SVR8", "gene_name": "LOC789148", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR8" } ] } ] }, { "uniprot_ac": "A0AAA9T9T1", "gene_name": "ERAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9T9T1", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNQ2" } ] } ] }, { "uniprot_ac": "A0AAA9TS74", "gene_name": "RAB36", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TS74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9TS74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ] } ] }, { "uniprot_ac": "A0AAA9TWE6", "gene_name": "RAB35", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TWE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9TWE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ] } ] }, { "uniprot_ac": "A0AAF6YME1", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0AAF6YME1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YME1" } ] } ] }, { "uniprot_ac": "A0AAF6YXF5", "gene_name": "RAB19", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6YXF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXF5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAF6YXF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXF5" } ] } ] }, { "uniprot_ac": "A0AAF6Z672", "gene_name": "TUFM", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z672", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z672" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "A0AAF6Z672", "database": "UniProtKB", "url": 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[ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P4Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4Y3" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "A0ABI0P4Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4Y3" } ] } ] }, { "uniprot_ac": "A4FUD1", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A4FUD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD1" } ] } ] }, { "uniprot_ac": "A4FV54", "gene_name": "RAB8A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A4FV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV54" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A4FV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV54" } ] } ] 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"activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A6QR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR46" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A6QR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR46" } ] } ] }, { "uniprot_ac": "E1BJA0", "gene_name": "RAB33A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "E1BJA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "E1BJA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJA0" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": 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"evidence": [ { "id": "F1MHP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHP4" } ] } ] }, { "uniprot_ac": "F1MM29", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1MM29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM29" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1MM29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM29" } ] } ] }, { "uniprot_ac": "F1MNI4", "gene_name": "RAB5B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1MNI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNI4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1MNI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNI4" } ] } ] }, { "uniprot_ac": "F1MX39", "gene_name": "RAB42", 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Classification" ] }, { "id": "A0A3Q1LFV9", "url": "https://www.orthodb.org/?gene=A0A3Q1LFV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28676", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28676", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28676:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28676:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-201556", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LFV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFV9-1", "url": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079528.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079528.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057151.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057151.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-201556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-201556", "resource": "Reactome", "description": "Signaling by ALK" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFV9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 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"categories": [ "Protein" ] }, { "id": "A0A3Q1MKG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEARGSGQEELPCVRGDFLPDPPLISNCWNPSLGTQIDKDSIRINQRGSVKHYQYPQDSFWNQVRMSLQTRPRLLNLAAVSLLRDEALAITALEYLPIELFPPLFMEAFCGSRSETLKAMVYAWPFVRLPLGGLMQKPHLGTLQAVLDGLDILLAQKNHSKRCKLRVLDLRNTGQDFWKMWSGSSVHVSSSSSMTPIAEVRSRTEQPLAPLEVFIELHFKESTIDDFLIYLIRWVEQRKASIHLCSNKLKIASMSLENIVQVLGIVQLDCIQEVEVSCIWHLSTLAMFAPFLGQMSNIQRLHLSHIHGLAFEEEEEYHHAVQITSQFRRLYHLRDLYLETPSFLEGCLNQMLRCLMTPLDNLAIIHSLLTDSDLTHLSQCPNISQLKSLDLTGDLLTYANAERLSVLLEKVAGTLEKLDLNMCGISDVHLEAILPALSHCFQLKSFSMCGNLLSMAIMEKMLRHTSALPSLNKELYPVPQDSLLSRGLHQPQRLAQCRAELFEILKDLGRPRTIWISSISCPQCEGHAFYHPEPIIYQGNILA", "length": 544, "header": "tr|A0A3Q1LFW5-1|A0A3Q1LFW5_BOVIN Isoform 1 of Melanoma antigen preferentially expressed in tumors-like OS=Bos taurus OX=9913 GN=LOC517884 PE=3 SV=2 CANONICAL=A0A3Q1LFW5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5/entry", "sequence": { "sequence": "MSEARGSGQEELPCVRGDFLPDPPLISNCWNPSLGTQIDKDSIRINQRGSVKHYQYPQDSFWNQVRMSLQTRPRLLNLAAVSLLRDEALAITALEYLPIELFPPLFMEAFCGSRSETLKAMVYAWPFVRLPLGGLMQKPHLGTLQAVLDGLDILLAQKNHSKRCKLRVLDLRNTGQDFWKMWSGSSVHVSSSSSMTPIAEVRSRTEQPLAPLEVFIELHFKESTIDDFLIYLIRWVEQRKASIHLCSNKLKIASMSLENIVQVLGIVQLDCIQEVEVSCIWHLSTLAMFAPFLGQMSNIQRLHLSHIHGLAFEEEEEYHHAVQITSQFRRLYHLRDLYLETPSFLEGCLNQMLRCLMTPLDNLAIIHSLLTDSDLTHLSQCPNISQLKSLDLTGDLLTYANAERLSVLLEKVAGTLEKLDLNMCGISDVHLEAILPALSHCFQLKSFSMCGNLLSMAIMEKMLRHTSALPSLNKELYPVPQDSLLSRGLHQPQRLAQCRAELFEILKDLGRPRTIWISSISCPQCEGHAFYHPEPIIYQGNILA", "length": 544, "header": "tr|A0A3Q1LFW5-1|A0A3Q1LFW5_BOVIN Isoform 1 of Melanoma antigen preferentially expressed in tumors-like OS=Bos taurus OX=9913 GN=LOC517884 PE=3 SV=2 CANONICAL=A0A3Q1LFW5-1" }, "locus": { "chromosome": "16", "start_pos": 54536059, "end_pos": 54502305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071176.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071176.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057161.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057161.2" } ] } }, { "isoform_ac": "A0A3Q1MKG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKG7/entry", "sequence": { "sequence": "MMCLKLRELDESFDNSDFLPDPPLISNCWNPSLGTQIDKDSIRINQRGSVKHYQYPQDSFWNQVRMSLQTRPRLLNLAAVSLLRDEALAITALEYLPIELFPPLFMEAFCGSRSETLKAMVYAWPFVRLPLGGLMQKPHLGTLQAVLDGLDILLAQKNHSKRCKLRVLDLRNTGQDFWKMWSGSSVHVSSSSSMTPIAEVRSRTEQPLAPLEVFIELHFKESTIDDFLIYLIRWVEQRKASIHLCSNKLKIASMSLENIVQVLGIVQLDCIQEVEVSCIWHLSTLAMFAPFLGQMSNIQRLHLSHIHGLAFEEEEEYHHAVQITSQFRRLYHLRDLYLETPSFLEGCLNQMLRCLMTPLDNLAIIHSLLTDSDLTHLSQCPNISQLKSLDLTGDLLTYANAERLSVLLEKVAGTLEKLDLNMCGISDVHLEAILPALSHCFQLKSFSMCGNLLSMAIMEKMLRHTSALPSLNKELYPVPQDSLLSRGLHQPQRLAQCRAELFEILKDLGRPRTIWISSISCPQCEGHAFYHPEPIIYQGNILA", "length": 543, "header": "tr|A0A3Q1MKG7-1|A0A3Q1LFW5_BOVIN Computationally mapped isoform of Melanoma antigen preferentially expressed in tumors-like OS=Bos taurus OX=9913 GN=LOC517884 PE=3 SV=2 CANONICAL=A0A3Q1LFW5-1" }, "locus": { "chromosome": "16", "start_pos": 54520002, "end_pos": 54502305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085754.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085754.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072027.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072027.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" }, { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LFW5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 544, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LFW5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LFW5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 383, "end_pos": 385 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LFW9-1", "uniprot_ac": "A0A3Q1LFW9", "uniprot_id": "A0A3Q1LFW9_BOVIN", "mass": { "chemical_mass": 39528.0, "monoisotopic_mass": 39528.0 }, "refseq": { "ac": "XP_059741670", "name": "transcription factor EC isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741670" }, "gene_names": [ { "name": "TFEC", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ] }, { "name": "TFEC", "type": "synonym", "evidence": [ { "id": "XP_059741670", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741670" } ] } ], "protein_names": [ { "name": "Transcription factor EC", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9/entry#names_and_taxonomy" } ] }, { "name": "transcription factor EC isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059741670", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741670" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TFEC", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9", "locus": { "chromosome": "4", "start_pos": 52499410, "end_pos": 52282331, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014228", "url": "https://www.ensembl.org/id/ENSBTAG00000014228" } ] } } ], "crossref": [ { "id": "A0A3Q1LFW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LFW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014228", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014228", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18925", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18925", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539016", "url": "https://www.ncbi.nlm.nih.gov/gene/539016", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KHQVKQY", "url": "https://omabrowser.org/oma/group/KHQVKQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFW9", "url": "https://www.orthodb.org/?gene=A0A3Q1LFW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MD59", "url": "https://www.orthodb.org/?gene=A0A3Q1MD59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1ML66", "url": "https://www.orthodb.org/?gene=F1ML66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45776:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45776:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11851", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11851", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059741670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741670", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCA5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD59", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD59-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ML66", "url": "https://www.uniprot.org/uniprotkb/F1ML66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ML66-1", "url": "https://www.uniprot.org/uniprotkb/F1ML66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEFGWCGQVPAHFESPARTQLQKVQRQQVKPFMTLDHQILNQSFKRSHPPTPSSELLVQHGHPSPESDTGLTGNPLTKLLTLGKEDDNTEWHVSGSILDVYSGEQEISPVNMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRAQELEHRQKKLEQANRRLLLRIQELEIQARAHGLPTLASLVTVDLGAHITKQTHLEQNSGDYCQQLVLSQGTSPELCDQAMAFSDPLSHFTDLSFSAALKEEQRLDNMLLDDTVSPFGTDPLLSAISPAVSKESSRRSSFSSEDGDEL", "length": 350, "header": "tr|A0A3Q1LFW9-1|A0A3Q1LFW9_BOVIN Isoform 1 of Transcription factor EC OS=Bos taurus OX=9913 GN=TFEC PE=3 SV=1 CANONICAL=A0A3Q1LFW9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9/entry", "sequence": { "sequence": "MLEFGWCGQVPAHFESPARTQLQKVQRQQVKPFMTLDHQILNQSFKRSHPPTPSSELLVQHGHPSPESDTGLTGNPLTKLLTLGKEDDNTEWHVSGSILDVYSGEQEISPVNMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRAQELEHRQKKLEQANRRLLLRIQELEIQARAHGLPTLASLVTVDLGAHITKQTHLEQNSGDYCQQLVLSQGTSPELCDQAMAFSDPLSHFTDLSFSAALKEEQRLDNMLLDDTVSPFGTDPLLSAISPAVSKESSRRSSFSSEDGDEL", "length": 350, "header": "tr|A0A3Q1LFW9-1|A0A3Q1LFW9_BOVIN Isoform 1 of Transcription factor EC OS=Bos taurus OX=9913 GN=TFEC PE=3 SV=1 CANONICAL=A0A3Q1LFW9-1" }, "locus": { "chromosome": "4", "start_pos": 52499043, "end_pos": 52359495, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084080.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084080.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057172.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057172.1" } ] } }, { "isoform_ac": "A0A3Q1MCA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCA5/entry", "sequence": { "sequence": "MMKEKEKNIAIVKVIDTSKLKLVSGSILDVYSGEQEISPVNMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRAQELEHRQKKLEQANRRLLLRIQELEIQARAHGLPTLASLVTVDLGAHITKQTHLEQNSGDYCQQLVLSQGTSPELCDQAMAFSDPLSHFTDLSFSAALKEEQRLDNMLLDDTVSPFGTDPLLSAISPAVSKESSRRSSFSSEDGDEL", "length": 279, "header": "tr|A0A3Q1MCA5-1|A0A3Q1LFW9_BOVIN Computationally mapped isoform of Transcription factor EC OS=Bos taurus OX=9913 GN=TFEC PE=3 SV=1 CANONICAL=A0A3Q1LFW9-1" }, "locus": { "chromosome": "4", "start_pos": 52499044, "end_pos": 52461916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072765.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072765.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067956.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067956.2" } ] } }, { "isoform_ac": "A0A3Q1MD59-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD59/entry", "sequence": { "sequence": "MTLDHQILNQSFKRSHPPTPSSELLVQHGHPSPESDTGLTGNPLTKLLTLGKEDDNTEWHMEDIIEDIIGMDPSFKEEGTDSPLLMQRTVSGSILDVYSGEQEISPVNMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRAQELEHRQKKLEQANRRLLLRIQELEIQARAHGLPTLASLVTVDLGAHITKQTHLEQNSGDYCQQLVLSQGTSPELCDQAMAFSDPLSHFTDLSFSAALKEEQRLDNMLLDDTVSPFGTDPLLSAISPAVSKESSRRSSFSSEDGDEL", "length": 346, "header": "tr|A0A3Q1MD59-1|A0A3Q1LFW9_BOVIN Computationally mapped isoform of Transcription factor EC OS=Bos taurus OX=9913 GN=TFEC PE=3 SV=1 CANONICAL=A0A3Q1LFW9-1" }, "locus": { "chromosome": "4", "start_pos": 52499043, "end_pos": 52434835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074834.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074834.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070556.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070556.1" } ] } }, { "isoform_ac": "F1ML66-1", "url": "https://www.uniprot.org/uniprotkb/F1ML66/entry", "sequence": { "sequence": "MTLDHQILNQSFKRSHPPTPSSELLVQHGHPSPESDTGLTGNPLTKLLTLGKEDDNTEWHVSGSILDVYSGEQEISPVNMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRAQELEHRQKKLEQANRRLLLRIQELEIQARAHGLPTLASLVTVDLGAHITKQTHLEQNSGDYCQQLVLSQGTSPELCDQAMAFSDPLSHFTDLSFSAALKEEQRLDNMLLDDTVSPFGTDPLLSAISPAVSKESSRRSSFSSEDGDEL", "length": 317, "header": "tr|F1ML66-1|F1ML66_BOVIN Computationally mapped isoform of Transcription factor EC OS=Bos taurus OX=9913 GN=TFEC PE=3 SV=1 CANONICAL=A0A3Q1LFW9-1" }, "locus": { "chromosome": "4", "start_pos": 52499043, "end_pos": 52434835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018918.6", "url": "https://www.ensembl.org/id/ENSBTAT00000018918.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018918.5", "url": "https://www.ensembl.org/id/ENSBTAP00000018918.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LFW9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 350, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LFW9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LFW9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LFW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFW9" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 196, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], 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], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A3Q1LFX2", "uniprot_id": "A0A3Q1LFX2_BOVIN", "mass": { "chemical_mass": 119952.0, "monoisotopic_mass": 119952.0 }, "refseq": { "ac": "XP_005217686", "name": "folliculin-interacting protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217686" }, "gene_names": [ { "name": "FNIP2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ] }, { "name": "FNIP2", "type": "synonym", "evidence": [ { "id": "XP_005217686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217686" } ] } ], "protein_names": [ { "name": "Folliculin interacting protein 2", "type": "synonym", "evidence": [ { "id": "A0A3Q1LFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2/entry#names_and_taxonomy" } ] }, { "name": "folliculin-interacting protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005217686", "database": 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"id": "SRCSFKP", "url": "https://omabrowser.org/oma/group/SRCSFKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFX2", "url": "https://www.orthodb.org/?gene=A0A3Q1LFX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMW7", "url": "https://www.orthodb.org/?gene=A0A3Q1LMW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MB64", "url": "https://www.orthodb.org/?gene=A0A3Q1MB64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NF19", "url": "https://www.orthodb.org/?gene=A0A3Q1NF19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21634:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21634:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005217686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217686", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFX2-1", "url": 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"MCGCSARTTAQPRGWRDAAQGVSDGRLHRTLFCTRTRKHARVGRSPDAPELSNSWSCSELDLNEIRLIVYQDCERRGRQVLFDSKAVHKMEEMAAQRTEDLPAKVPAKSCSGGGPAAHGPSGGSLPHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYQGSTLKIHYIRSPPQLMVSKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNNLGPCRTGSNLGALQGCGGKLPPGAAEGGPLRLSRSASFFAAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIIPRRSMDETFSLAEETCSSNPAIVRRKKIAISIIFSLCEKEEAQRNFQDFFFSHFPLFESHMNRLKSAIEKAMISCRKIAESSLRVQFYVSRLMEALGEFRGTIWSLYSVPRIAEPVWLAMMSSTLERTQLCQRFLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQLVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVLGKQKDLVQRILYVLTYFVRCSELQENQLMWSGGPAQGEQILHGSSITTALERGEVEESEYVVVTVRSEPALLPPTLPVTTAEGLAGVPVDADPRDLCPQLDGEGGGALEKSLTAHGAWRPQGVSCGEEESKEPPRGGSARLPSGAGVGAGLKMSPPAIGAEPGGEMPKRLPDRSAARPCPDGRLRDRPPWEKVTFHIGSSVSPESDFESRTKAMEERLQACRCAEPEPAQGPLAGPGAAADPAQEGQDQCTLMCSRSPGVSGVGRDVRTEAAVEVAGALGAPATPCAPASPAGAPARPGGQRGKDADALVTSGCTTPVPSGDAGFRVEGGLPRNESSDSALGDSDDDTCAAASPDLGPGSDPDADHDQSEGSLEVELPLPRSQSISNPNVRNFGRSLLAGYCPTYMPDLVLHGTSSDEKLKQCLAADLVHTVQHPVLDEPIAEAVCIIADTDKWSVQVATSQRKAVDGMKLGQEVLVSSQVSSLLQSILQLYRLHLPADFCVMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDLPLLTAIASTHSPYVAQILL", "length": 1110, "header": "tr|A0A3Q1LFX2-1|A0A3Q1LFX2_BOVIN Isoform 1 of Folliculin interacting protein 2 OS=Bos taurus OX=9913 GN=FNIP2 PE=3 SV=2 CANONICAL=A0A3Q1LFX2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2/entry", "sequence": { "sequence": "MCGCSARTTAQPRGWRDAAQGVSDGRLHRTLFCTRTRKHARVGRSPDAPELSNSWSCSELDLNEIRLIVYQDCERRGRQVLFDSKAVHKMEEMAAQRTEDLPAKVPAKSCSGGGPAAHGPSGGSLPHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYQGSTLKIHYIRSPPQLMVSKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNNLGPCRTGSNLGALQGCGGKLPPGAAEGGPLRLSRSASFFAAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIIPRRSMDETFSLAEETCSSNPAIVRRKKIAISIIFSLCEKEEAQRNFQDFFFSHFPLFESHMNRLKSAIEKAMISCRKIAESSLRVQFYVSRLMEALGEFRGTIWSLYSVPRIAEPVWLAMMSSTLERTQLCQRFLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQLVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVLGKQKDLVQRILYVLTYFVRCSELQENQLMWSGGPAQGEQILHGSSITTALERGEVEESEYVVVTVRSEPALLPPTLPVTTAEGLAGVPVDADPRDLCPQLDGEGGGALEKSLTAHGAWRPQGVSCGEEESKEPPRGGSARLPSGAGVGAGLKMSPPAIGAEPGGEMPKRLPDRSAARPCPDGRLRDRPPWEKVTFHIGSSVSPESDFESRTKAMEERLQACRCAEPEPAQGPLAGPGAAADPAQEGQDQCTLMCSRSPGVSGVGRDVRTEAAVEVAGALGAPATPCAPASPAGAPARPGGQRGKDADALVTSGCTTPVPSGDAGFRVEGGLPRNESSDSALGDSDDDTCAAASPDLGPGSDPDADHDQSEGSLEVELPLPRSQSISNPNVRNFGRSLLAGYCPTYMPDLVLHGTSSDEKLKQCLAADLVHTVQHPVLDEPIAEAVCIIADTDKWSVQVATSQRKAVDGMKLGQEVLVSSQVSSLLQSILQLYRLHLPADFCVMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDLPLLTAIASTHSPYVAQILL", "length": 1110, "header": "tr|A0A3Q1LFX2-1|A0A3Q1LFX2_BOVIN Isoform 1 of Folliculin interacting protein 2 OS=Bos taurus OX=9913 GN=FNIP2 PE=3 SV=2 CANONICAL=A0A3Q1LFX2-1" }, "locus": { "chromosome": "17", "start_pos": 40197698, "end_pos": 40112761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081446.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081446.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057177.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057177.2" } ] } }, { "isoform_ac": "A0A3Q1LMW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMW7/entry", "sequence": { "sequence": "MAPTLLQRLFNRKGGGGSAAATAPGRAPREGPAFSWSCSELDLNEIRLIVYQDCERRGRQVLFDSKAVHKMEEMAAQRTEDLPAKVPAKSCSGGGPAAHGPSGGSLPHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYQGSTLKIHYIRSPPQLMVSKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNNLGPCRTGSNLGALQGCGGKLPPGAAEGGPLRLSRSASFFAAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIIPRRSMDETFSLAEETCSSNPAIVRRKKIAISIIFSLCEKEEAQRNFQDFFFSHFPLFESHMNRLKSAIEKAMISCRKIAESSLRVQFYVSRLMEALGEFRGTIWSLYSVPRIAEPVWLAMMSSTLERTQLCQRFLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQLVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVLGKQKDLVQRILYVLTYFVRCSELQENQLMWSGGPAQGEQILHGSSITTALERGEVEESEYVVVTVRSEPALLPPTLPVTTAEGLAGVPVDADPRDLCPQLDGEGGGALEKSLTAHGAWRPQGVSCGEEESKEPPRGGSARLPSGAGVGAGLKMSPPAIGAEPGGEMPKRLPDRSAARPCPDGRLRDRPPWEKVTFHIGSSVSPESDFESRTKAMEERLQACRCAEPEPAQGPLAGPGAAADPAQEGQDQCTLMCSRSPGVSGVGRDVRTEAAVEVAGALGAPATPCAPASPAGAPARPGGQRGKDADALVTSGCTTPVPSGDAGFRVEGGLPRNESSDSALGDSDDDTCAAASPDLGPGSDPDADHDQSEGSLEVELPLPRSQSISNPNVRNFGRSLLAGYCPTYMPDLVLHGTSSDEKLKQCLAADLVHTVQHPVLDEPIAEAVCIIADTDKWSVQVATSQRKAVDGMKLGQEVLVSSQVSSLLQSILQLYRLHLPADFCVMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDLPLLTAIASTHSPYVAQILL", "length": 1091, "header": "tr|A0A3Q1LMW7-1|A0A3Q1LFX2_BOVIN Computationally mapped isoform of Folliculin interacting protein 2 OS=Bos taurus OX=9913 GN=FNIP2 PE=3 SV=1 CANONICAL=A0A3Q1LFX2-1" }, "locus": { "chromosome": "17", "start_pos": 40235795, "end_pos": 40112761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070927.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070927.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058078.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058078.1" } ] } }, { "isoform_ac": "A0A3Q1MB64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MB64/entry", "sequence": { "sequence": "MCGCSARTTAQPRGWRDAAQGVSDGRLHRTLFCTRTRKHARVGRSPDAPELSNSWSCSELDLNEIRLIVYQDCERRGRQVLFDSKAVHKMEEMAAQRTEDLPAKVPAKSCSGGGPAAHGPSGGSLPHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYQGSTLKIHYIRSPPQLMVSKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNNLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIIPRRSMDETFSLAEETCSSNPAIVRRKKIAISIIFSLCEKEEAQRNFQDFFFSHFPLFESHMNRLKSAIEKAMISCRKIAESSLRVQFYVSRLMEALGEFRGTIWSLYSVPRIAEPVWLAMMSSTLERTQLCQRFLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQLVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVLGKQKDLVQRILYVLTYFVRCSELQENQLMWSGGPAQGEQILHGSSITTALERGEVEESEYVVVTVRSEPALLPPTLPVTTAEGLAGVPVDADPRDLCPQLDGEGGGALEKSLTAHGAWRPQGVSCGEEESKEPPRGGSARLPSGAGVGAGLKMSPPAIGAEPGGEMPKRLPDRSAARPCPDGRLRDRPPWEKVTFHIGSSVSPESDFESRTKAMEERLQACRCAEPEPAQGPLAGPGAAADPAQEGQDQCTLMCSRSPGVSGVGRDVRTEAAVEVAGALGAPATPCAPASPAGAPARPGGQRGKDADALVTSGCTTPVPSGDAGFRVEGGLPRNESSDSALGDSDDDTCAAASPDLGPGSDPDADHDQSEGSLEVELPLPRSQSISNPNVRNFGRSLLAGYCPTYMPDLVLHGTSSDEKLKQCLAADLVHTVQHPVLDEPIAEAVCIIADTDKWSVQVATSQRKAVDGMKLGQEVLVSSQVSSLLQSILQLYRLHLPADFCVMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDLPLLTAIASTHSPYVAQILL", "length": 1080, "header": "tr|A0A3Q1MB64-1|A0A3Q1LFX2_BOVIN Computationally mapped isoform of Folliculin interacting protein 2 OS=Bos taurus OX=9913 GN=FNIP2 PE=3 SV=1 CANONICAL=A0A3Q1LFX2-1" }, "locus": { "chromosome": "17", "start_pos": 40197698, "end_pos": 40112761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085360.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085360.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071283.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071283.1" } ] } }, { "isoform_ac": "A0A3Q1NF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NF19/entry", "sequence": { "sequence": "MRLRWGCPCRVRAMPGPCWSCSELDLNEIRLIVYQDCERRGRQVLFDSKAVHKMEEMAAQRTEDLPAKVPAKSCSGGGPAAHGPSGGSLPHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYQGSTLKIHYIRSPPQLMVSKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNNLGPCRTGSNLGALQGCGGKLPPGAAEGGPLRLSRSASFFAAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIIPRRSMDETFSLAEETCSSNPAIVRRKKIAISIIFSLCEKEEAQRNFQDFFFSHFPLFESHMNRLKSAIEKAMISCRKIAESSLRVQFYVSRLMEALGEFRGTIWSLYSVPRIAEPVWLAMMSSTLERTQLCQRFLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQLVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVLGKQKDLVQRILYVLTYFVRCSELQENQLMWSGGPAQGEQILHGSSITTALERGEVEESEYVVVTVRSEPALLPPTLPVTTAEGLAGVPVDADPRDLCPQLDGEGGGALEKSLTAHGAWRPQGVSCGEEESKEPPRGGSARLPSGAGVGAGLKMSPPAIGAEPGGEMPKRLPDRSAARPCPDGRLRDRPPWEKVTFHIGSSVSPESDFESRTKAMEERLQACRCAEPEPAQGPLAGPGAAADPAQEGQDQCTLMCSRSPGVSGVGRDVRTEAAVEVAGALGAPATPCAPASPAGAPARPGGQRGKDADALVTSGCTTPVPSGDAGFRVEGGLPRNESSDSALGDSDDDTCAAASPDLGPGSDPDADHDQSEGSLEVELPLPRSQSISNPNVRNFGRSLLAGYCPTYMPDLVLHGTSSDEKLKQCLAADLVHTVQHPVLDEPIAEAVCIIADTDKWSVQVATSQRKAVDGMKLGQEVLVSSQVSSLLQSILQLYRLHLPADFCVMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDLPLLTAIASTHSPYVAQILL", "length": 1074, "header": "tr|A0A3Q1NF19-1|A0A3Q1LFX2_BOVIN Computationally mapped isoform of Folliculin interacting protein 2 OS=Bos taurus OX=9913 GN=FNIP2 PE=3 SV=2 CANONICAL=A0A3Q1LFX2-1" }, "locus": { "chromosome": "17", "start_pos": 40216649, "end_pos": 40112761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067422.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067422.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070282.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070282.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 830, "start_aa": "Thr", "end_pos": 830, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr830", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2U512-1", "protein_name": "Folliculin interacting protein 2", "gene_name": "FNIP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCGGTPKATNGAGGQTERARNNSDVPLGNDFSCTKLDERIRKCLRDRSVSCVSRVTRQLQKSWSSSEFDLNEIRLIVYQDCERRGRQVLFDSKAVRKIDEAVVQKMAEDAPVKTSVRNCQASNGNNSISSHNPSISVMQNVKEQIPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARVGSFSGSNNNLQDSFEYISQDPSLGKLSSNQNGLGTCRSGSNLGVLQLCSSKLLQGVSEGGPLRLIRSASFFAAHSTPVDMPSRGQNEDRDSGIARSASLSSLLVTPFPSPSSSSSSSSSYQRRWLRSQTTSLENGIIPRWSTEEMFSMADESCSSNPAMVRRKKIAISIIFSLPEKEDAQRNFQDFFFSHFPLFESHMNKLKYAIEKAMISCRKIAESSQRVQVYISRVMDALGEFRITIWNLYSVPRIAEPVWLNMMSNTLEKNQLCQRFLKEFTFLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQFVNMLAKSHPYNPLWAQLGDLYGAIGSPVRLTRTVVVGKRKELVQRLLYVLTYFIRCSELQENQLTWSEAVGEEEQVLNGSKITTALEKGEIEESDYVVVTVKNEPALVPPILPPKSDRNKNHTIAEWVYNPKGTYTVPTSSKEKKEIIGKVSQNSETSVDCLTSTLHKGATDSGKRIVTDTGAVPYHFEEPSNLEDLTDVRKNKNQNERKVEKQLSSRSSALPCPERSGHRSLHLEKVTFQIGSSASPDSDLETRRREMEENLKVLRKNTEVIIHCASSSTNLTVDASQNQKESCETASLPYSKHSICYAQIPFCEGQGSILNNQHMENKGTEGNLENTVSGEVLLSIDNIETVTLPSEKETRTSCSGNLESYSPGCVEVDSAVKRESPKLGVKDVPCGDARRKTPFRVEGDIPRNESSDSALGASDEEGDCCIPDEVRHDNVSKRLEEFAEVELPLPRSNTVSRQCVKNFGRSLLGGYCHTYVPDLVLHGVNNDEKLKQCLLADLLHAMHHPVLDEPIAEAVCIIADTDKWNVQVATSQRKVMDSMKLGKDVLVSSQVSSLLQSILQLYKLNLPADFCIMHLEDRLQEMYLKSKMLSEYLRGHTRVHIKELGIVLGIESNDLPLLAAIASTHSPYVAQILL", "length": 1165 }, "evidence": [ { "id": "A0A3Q1LFX2", "url": "https://omabrowser.org/oma/group/A0A3Q1LFX2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8M9PJ89-1", "protein_name": "Folliculin-interacting protein 2 isoform X1", "gene_name": "fnip2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVCMHACRHTHTLCSGLPLKMKIKSRTKTTSRWLFIHEDASWNSWASAEFDLAQIRLIVYQDCERRGRQVLFDSKAIHKLDASEPTADETKTPPNRSGACHIGSQANEKDKPPTYQYTRPASDVNMLGEMMFGSVSMSYKGSTLKIHHIRSPPQLMVSKVFSTRFGSSSTSGSTNTLQDSFESMSQTFPSHTSSSIGVRHVPSAPLLSLVRSASFFAAHSNPVDMPSRGHSEDGDSGIARSASLSSLLATPQPSPGSSFSSGCASSYQRRWLRSQATSLQHGPMPRWNAEEMFNLSDESCSSNPAMIRRKKIAISIIISLPEREEENHNFQEFFFSHFPLFESHMNKLKTAIERAMIVCRRIAESSQRVQVYLCRVMEALGEFRMTVWNLYMAPRISEPVWLSMISQSAERNLLCQRFLKEMSLLMEHGVKSQFLSALLTAVLTHHLAWVPTVMPSNLPPIKPACQKPTSQTVDLLAKSHPYNPLWAQLGDLYGALGSPVRVCRTVVVGRRRELVQRVLYILSYFIRCSDLQEHVQPQGQKDNPANPCTSPTTDPNPASERICEKTFPPPPDTIKPIPGTFMEQNDETVSADTHSTNTPTGLEASMVRPECTEMGPECFGEHVDSVGGGLEHILANQSPLPQRVQFHIGSPREVENVGQAGGLMCGGQGLDRKLHQRLLTDIRRNESSDSALGDSDDEETSSREMYMAAEQTEYELPLPSSQVESRASVNHFGRSLLGGYCPQYMPDFALHGISSDLRLKQCLMADLEHTVLHPALDEPVAEALCIVADTDRLSVQVVTSQRRMCEGGRLGRDVMVSNLIHTLITSVLQLYALNIAADFCVMHLEDRLQEVYFKSRSLAEYLRGQTRVHVKELGLALGIESSDIPLLAAVASTHSPYVAQILL", "length": 904 }, "evidence": [ { "id": "A0A3Q1LFX2", "url": "https://omabrowser.org/oma/group/A0A3Q1LFX2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LCB8-1", "protein_name": "Folliculin interacting protein 2", "gene_name": "Fnip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCGGTANSTNWPVGQQESARCVTDATSGVGRIFKTLVCAKISKCARGGRDTNSMVLNHSWSCSEFDLSDIRLIVYQDCERRGRQVMFDSRAVQKVEETAAQKAEDVPIKMSARCCQESGSVSSSSSSSSNSSSSQSSGGSSQHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARMGSFCGSTNNLQDSFEYINQDPQAGKLNTNQNSLGPCRTGSNLGLLQACSGKLLQGVSEGGPLRLTRSASFFAAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIFPRRSTDETFSLAEETCSSNPSIVRRKKIAISIIFSLCEREAAQRDFQDFFFSHFPLFESHMNRLKSAIEKAMISCRKISESSLRVQFYVSRLMEALGEFRGTIWNLYSVPRIAEPVWLTMMSNTLEKNQLCQRFLKEFILLIEQVNKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKTFSEKRTSQSVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVIGKQKDLVQRILYVLTYFLRCSELQENQLTWSGNHSDDDQVINGSKIVTALEKGEVEESEYVVVTVSNEPALVPPVLPPGTSERTSPEPTVVAEIPEGINTELGHKPERNRCKRPEQYSEASSMGFQEAETDNSWTPRGMFCEDKQNDQQVAQDCSSGPPSCEVPRVKRRMDQQTFHEELHGEMLKKRAERSAAWPCPDRHSQEGPPVEKVTFHIGSSISPESDFESRTKRMEERLKACGHFHGASASARSSMDTGLTQDQQASGCSFKADFQKDITPQDHCLGEEGVSENRGLRANIRANMAHAVGQLSQADGPLAPSTCTAESGWRQLEQTRDVQLKGNKGPSSEPVPNRCRQQGDLLIAADVPYGDASGKANYRSEGDIPRNESLDSALGDSDDEACVLALLELGHNCDRTEGSFEVELPLPRSQSTSKPNVRNFGRSLLAGYCATYMPDLVLHGTSSDEKLKQCLAADLVHTVHHPVLDEPIAEAVCIIADTDKWTVQVATSQRKVTDAMKLGQDVLVSNQVSSLLQSILQLHKLHLPADFCIMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESSDLPLLTAIASTHSPYVAQILL", "length": 1170 }, "evidence": [ { "id": "A0A3Q1LFX2", "url": "https://omabrowser.org/oma/group/A0A3Q1LFX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TD3-1", "protein_name": "Folliculin-interacting protein 2", "gene_name": "Fnip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPTLLQKLFNKRGGGAASAQARPPKEEPAFSWSCSEFGLSDIRLLVYQDCERRGRQVMFDSRAVQKMEEAAAQKAEDVPIKMSARCCQESSSSSGSSSSGSSSSHGFGGSLQHAKQQLPKYQYTRPASDVSMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSATMGSFCGSTNNLQDSFEYINQDPQAGKLNTNQYNLGPFRTGSNLAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIFPRRSTDETFSLAEETCSSNPAMVRRKKIAISIIFSLCEREAAQRDFQDFFFSHFPLFESHMNRLKGAIEKAMISCRKISESSLRVQFYVSRLMEALGEFRGTIWNLYSVPRIAEPVWLTMMSNTLEKNQLCQRFLKEFILLIEQVNKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQSVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVIGKQKDLVQRILYVLTYFLRCSELQENQLSWSGNPSEDDQVINGSKIITALEKGEVEESEYVVVTVSSEPALVPPILPQGTAERRSPEPTVVAEISEGVNTSELGHKPEKNRCKRPEQNSEASSMGFQEAEPDSSWIPQGIFCEDKQNDQEATQDCSSSPPSCEVPRVRRRMDQQTLHSKLHGETLKKRAEQSAAWPCPDRHSQEDPPVEKVTFHIGSSISPESDFESRTKRMEERLKACGHFHGASASASSSMDTGLTQEQQGSGCSFKADFEKDITPQDHSSGGEGVSEDRGLRANMTHAVGQLSQVDGPLAHSLCAAESGRRLLEQTRDVQLKGYKGPSSEPVPNRCRQQGGLLIAADVPYGDASGKGNYRSEGDIPRNESLDSALGDSDDEACVLALLELGHSCDRTEESLEVELPLPRSQSTSKANVRNFGRSLLAGYCATYMPDLVLHGTSSDEKLKQCLAADLVHTVHHPVLDEPIAEAVCIIADTDKWTVQVATSQRKVTDTMKLGQDVLVSSQVSSLLQSILQLYKLHLPADFCIMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDLPLLTAIASTHSPYVAQILL", "length": 1108 }, "evidence": [ { "id": "A0A3Q1LFX2", "url": "https://omabrowser.org/oma/group/A0A3Q1LFX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P278-1", "protein_name": "Folliculin-interacting protein 2", "gene_name": "FNIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFSWSCSEFDLNEIRLIVYQDCDRRGRQVLFDSKAVQKIEEVTAQKTEDVPIKISAKCCQGSSSVSSSSSSSISSHSSSGGSSHHAKEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARMGSFCGSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENGIIPRRSTDETFSLAEETCSSNPAMVRRKKIAISIIFSLCEKEEAQRNFQDFFFSHFPLFESHMNRLKSAIEKAMISCRKIAESSLRVQFYVSRLMEALGEFRGTIWNLYSVPRIAEPVWLTMMSGTLEKNQLCQRFLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQSVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVVGKQKDLVQRILYVLTYFLRCSELQENQLTWSGNHGEGDQVLNGSKIITALEKGEVEESEYVVITVRNEPALVPPILPPTAAERHNPWPTGFPECPEGTDSRDLGLKPDKEANRRPEQGSEACSAGCLGPASDASWKPQNAFCGDEKNKEAPQDGSSRLPSCEVLGAGMKMDQQAVCELLKVEMPTRLPDRSVAWPCPDRHLREKPSLEKVTFQIGSFASPESDFESRMKKMEERVKACGPSLEASEAADVAQDPQVSRSPFKPGFQENVCCPQNRLSEGDEGESDKGFAEDRGSRNDMAADIAGQLSHAADLGTASHGAGGTGGRRLEATRGLYVKAAEGPVLEPVAPRCVQRGPGLVAGANIPCGDDNKKANFRTEGDIPRNESSDSALGDSDDEACASAMLDLGHGGDRTGGSLEVELPLPRSQSISTQNVRNFGRSLLAGYCPTYMPDLVLHGTGSDEKLKQCLVADLVHTVHHPVLDEPIAEAVCIIADTDKWSVQVATSQRKVTDNMKLGQDVLVSSQVSSLLQSILQLYKLHLPADFCIMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELGVVLGIESNDLPLLTAIASTHSPYVAQILL", "length": 1114 }, "evidence": [ { "id": "A0A3Q1LFX2", "url": "https://omabrowser.org/oma/group/A0A3Q1LFX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" }, { "name": "positive regulation of protein-containing complex assembly", "id": "GO:0031334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031334", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" }, { "name": "FNIP-folliculin RagC/D GAP", "id": "GO:1990877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990877", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" }, { "name": "ATPase inhibitor activity", "id": "GO:0042030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042030", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LFX2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1110, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LFX2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LFX2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFX2" }, { "id": "PS51836", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51836" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN FNIP1/2-type", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 1101, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 830 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 880, "end_pos": 882 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LGC2-1", "uniprot_ac": "A0A3Q1LGC2", "uniprot_id": "A0A3Q1LGC2_BOVIN", "mass": { "chemical_mass": 77218.0, "monoisotopic_mass": 77218.0 }, "refseq": {}, "gene_names": [ { "name": "HUNK", "type": "recommended", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ], "protein_names": [ { "name": "Hormonally up-regulated neu tumor-associated kinase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HUNK", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2", "locus": { "chromosome": "1", "start_pos": 3500644, "end_pos": 3629626, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020762", "url": "https://www.ensembl.org/id/ENSBTAG00000020762" } ] } } ], "crossref": [ { "id": "A0A3Q1LGC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LGC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020762", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020762", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14070", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "537640", "url": "https://www.ncbi.nlm.nih.gov/gene/537640", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:537640", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537640", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQYRMLS", "url": "https://omabrowser.org/oma/group/HQYRMLS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LGC2", "url": "https://www.orthodb.org/?gene=A0A3Q1LGC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MHW6", "url": "https://www.orthodb.org/?gene=F1MHW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LGC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHW6", "url": "https://www.uniprot.org/uniprotkb/F1MHW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHW6-1", "url": "https://www.uniprot.org/uniprotkb/F1MHW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAAAADGLLGEPAAPGGGGGGAEDAARPAAACEGSFLPAWVSGVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGHSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPAQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWLNENYVGKVPCNITYPNRISLEDLSPSVVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDFQDSVCYKTQLYQIDRCRPTKEPYEDKKPKEQEKRGDFLHRPFSKKLDKNLPSHKQPSASLITQIQSTRALLKDRKASKPGFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPPQQGPGSTSLPIKEDPLMLDMVRSFESVDRDDQTELLSPSHHYRILNSPGGLARCERTLSPVLLPGSPLPLQTPLHPTLVSFAHEEKNSPPKEEGTCSPAPGPGNGPAQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSADRPLEASMPPLQPLAPTSLSFDLADGVKGQC", "length": 696, "header": "tr|A0A3Q1LGC2-1|A0A3Q1LGC2_BOVIN Isoform 1 of Hormonally up-regulated neu tumor-associated kinase OS=Bos taurus OX=9913 GN=HUNK PE=3 SV=2 CANONICAL=A0A3Q1LGC2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2/entry", "sequence": { "sequence": "MPAAAADGLLGEPAAPGGGGGGAEDAARPAAACEGSFLPAWVSGVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGHSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPAQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWLNENYVGKVPCNITYPNRISLEDLSPSVVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDFQDSVCYKTQLYQIDRCRPTKEPYEDKKPKEQEKRGDFLHRPFSKKLDKNLPSHKQPSASLITQIQSTRALLKDRKASKPGFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPPQQGPGSTSLPIKEDPLMLDMVRSFESVDRDDQTELLSPSHHYRILNSPGGLARCERTLSPVLLPGSPLPLQTPLHPTLVSFAHEEKNSPPKEEGTCSPAPGPGNGPAQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSADRPLEASMPPLQPLAPTSLSFDLADGVKGQC", "length": 696, "header": "tr|A0A3Q1LGC2-1|A0A3Q1LGC2_BOVIN Isoform 1 of Hormonally up-regulated neu tumor-associated kinase OS=Bos taurus OX=9913 GN=HUNK PE=3 SV=2 CANONICAL=A0A3Q1LGC2-1" }, "locus": { "chromosome": "1", "start_pos": 3629427, "end_pos": 3501648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074986.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074986.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057451.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057451.2" } ] } }, { "isoform_ac": "F1MHW6-1", "url": "https://www.uniprot.org/uniprotkb/F1MHW6/entry", "sequence": { "sequence": "MPAAAADGLLGEPAAPGGGGGGAEDAARPAAACEGSFLPAWVSGVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGHSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPAQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWLNENYVGKVPCNITYPNRISLEDLSPSVVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDFQDSVCYKTQLYQIDRCRPTKEPYEASLDTWTRDLEFHAVQDKKPKEQEKRGDFLHRPFSKKLDKNLPSHKQPSASLITQIQSTRALLKDRKASKPGFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPPQQGPGSTSLPIKEDPLMLDMVRSFESVDRDDQTELLSPSHHYRILNSPGGLARCERTLSPVLLPGSPLPLQTPLHPTLVSFAHEEKNSPPKEEGTCSPAPGPGNGPAQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSADRPLEASMPPLQPLAPTSLSFDLADGVKGQC", "length": 712, "header": "tr|F1MHW6-1|F1MHW6_BOVIN Computationally mapped isoform of Hormonally up-regulated neu tumor-associated kinase OS=Bos taurus OX=9913 GN=HUNK PE=3 SV=3 CANONICAL=A0A3Q1LGC2-1" }, "locus": { "chromosome": "1", "start_pos": 3629427, "end_pos": 3501648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027668.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027668.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027668.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027668.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:537640", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537640", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZV60-1", "protein_name": "Hormonally up-regulated neu tumor-associated kinase", "gene_name": "Hunk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAAAGDGLLGEPAAPGGDGGAEDTARPAAACEGSFLPAWVSGVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAINFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDSICYKTQLYQIEKCRATKEPYEASLDTWTKDFELHAVQDKKPKEQDKRADFLHRPFSKKLDKSLPSHKQPSPSLITQIQNTKALLKDRKASKSGFGDKDSFGCRNLFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKQEPHQPGPGSASMLPKEEPLLLDMVRSFESVDREDHIELLSSSHHYRILSSPVSLARRNSGERTLSPGLLSGSTSPLQTPLHSTLVSFTHEEKNSPPKEEGVCSPPPVPSNGLMQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSSERSLEVSMSPLQPTAPSSLSFDMADGVKGQC", "length": 714 }, "evidence": [ { "id": "A0A3Q1LGC2", "url": "https://omabrowser.org/oma/group/A0A3Q1LGC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Y4L8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "HUNK", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIRHPNIAQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEEHEARKYIRQLILAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPFPTQLSTAAVNFLRSLLEPDPAKRPNIQQALANRWLNENYPGRAPPNVTYPNRIHLEDLSQSVLLHMTEKLGYKNSDVINTVLSNRASHTLAIYFLLNKKLERYLASLRKSEVQDNICHKNQLYQIDKYKANKDSYEDKKLRKQEKKGEILHRQLPKKTEKSPVSYRQPSSCLISQIQNTKALLRDRKATKAGGAEKDSTSGLSPFHEPLATKAGFITSSSLEYLEAQQPLPRTPRLLKRQESPQQEPARAGGRAKDSPLILNIVHSFESVDREDQTDQVSPSHQYKILGSPMNFPSKSSSERTLSPLFQPGSTSPIHPNQVSFTYEEKAYPAKEEAVSPTQLVSNNPLGSPNCVKSRGRFPMMGIGQMLRKRNQTMQSVGDKPLEARMPQLQQMSPTQITFNADAVSGQC", "length": 579 }, "evidence": [ { "id": "A0A3Q1LGC2", "url": "https://omabrowser.org/oma/group/A0A3Q1LGC2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O88866-1", "protein_name": "Hormonally up-regulated neu tumor-associated kinase", "gene_name": "Hunk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPAAAGDGLLGEPAAPGGDGGAEDTTRPAAACEGSFLPAWVSGVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDSICYKTQLYQIEKCRATKEPYEASLDTWTRDFEFHAVQDKKPKEQEKRGDFLHRPFSKKLDKNLPSHKQPSPSLITQLQSTKALLKDRKASKSGFPDKDSFVCRNLFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKLEPHQPGPGSASILPKEEPLLLDMVRSFESVDREDHIELLSPSHHYRILSSPVSLARRNSSERTLSQGLLSGSTSPLQTPLHSTLVSFAHEEKNSPPKEEGVCSPPPVPSNGLLQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSSERSLDASMSPLQPTAPSSLSFDMADGVKGQC", "length": 714 }, "evidence": [ { "id": "A0A3Q1LGC2", "url": "https://omabrowser.org/oma/group/A0A3Q1LGC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P57058-1", "protein_name": "Hormonally up-regulated neu tumor-associated kinase", "gene_name": "HUNK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAAAGDGLLGEPAAPGGGGGAEDAARPAAACEGSFLPAWVSGVPRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDSLCYKTRLYQIEKYRAPKESYEASLDTWTRDLEFHAVQDKKPKEQEKRGDFLHRPFSKKLDKNLPSHKQPSGSLMTQIQNTKALLKDRKASKSSFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPHQPGPGSTGIPHKEDPLMLDMVRSFESVDRDDHVEVLSPSHHYRILNSPVSLARRNSSERTLSPGLPSGSMSPLHTPLHPTLVSFAHEDKNSPPKEEGLCCPPPVPSNGPMQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSADRPLEASLPPLQPLAPVNLAFDMADGVKTQC", "length": 714 }, "evidence": [ { "id": "A0A3Q1LGC2", "url": "https://omabrowser.org/oma/group/A0A3Q1LGC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 321, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 332, "end_pos": 334 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LGF4-1", "uniprot_ac": "A0A3Q1LGF4", "uniprot_id": "A0A3Q1LGF4_BOVIN", "mass": { "chemical_mass": 80796.0, "monoisotopic_mass": 80796.0 }, "refseq": { "ac": "XP_005213933", "name": "sciellin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213933" }, "gene_names": [ { "name": "SCEL", "type": "recommended", "evidence": [ { "id": "A0A3Q1LGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ] }, { "name": "SCEL", "type": "synonym", "evidence": [ { "id": "XP_005213933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213933" } ] } ], "protein_names": [ { "name": "Sciellin", "type": "synonym", "evidence": [ { "id": "A0A3Q1LGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4/entry#names_and_taxonomy" } ] }, { "name": "sciellin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005213933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213933" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SCEL", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4", "locus": { "chromosome": "12", "start_pos": 52808580, "end_pos": 52683457, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032821", "url": "https://www.ensembl.org/id/ENSBTAG00000032821" } ] } } ], "crossref": [ { "id": "A0A3Q1LGF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LGF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032821", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032821", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08368", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08368", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "784362", "url": "https://www.ncbi.nlm.nih.gov/gene/784362", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LGF4", "url": "https://www.orthodb.org/?gene=A0A3Q1LGF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M2D6", "url": "https://www.orthodb.org/?gene=A0A3Q1M2D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MNR8", "url": "https://www.orthodb.org/?gene=A0A3Q1MNR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N0U2", "url": "https://www.orthodb.org/?gene=A0A3Q1N0U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N181", "url": "https://www.orthodb.org/?gene=A0A3Q1N181", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15468", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15468", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15468:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15468:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_005213933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213933", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2D6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNR8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N0U2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N0U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N0U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N0U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N181", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N181", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N181-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N181-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYS5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYS5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ05", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1G4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1G4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVE9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVE9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PSE8", "url": "https://www.uniprot.org/uniprotkb/F6PSE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PSE8-1", "url": "https://www.uniprot.org/uniprotkb/F6PSE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGSKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 719, "header": "tr|A0A3Q1LGF4-1|A0A3Q1LGF4_BOVIN Isoform 1 of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=2 CANONICAL=A0A3Q1LGF4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LGF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGSKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 719, "header": "tr|A0A3Q1LGF4-1|A0A3Q1LGF4_BOVIN Isoform 1 of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=2 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074397.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074397.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057508.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057508.2" } ] } }, { "isoform_ac": "A0A3Q1M2D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2D6/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 697, "header": "tr|A0A3Q1M2D6-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=2 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075979.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075979.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064174.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064174.2" } ] } }, { "isoform_ac": "A0A3Q1MNR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNR8/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 698, "header": "tr|A0A3Q1MNR8-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=2 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081018.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081018.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072926.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072926.2" } ] } }, { "isoform_ac": "A0A3Q1N0U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N0U2/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNISEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGSKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNESSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 668, "header": "tr|A0A3Q1N0U2-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=3 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078210.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078210.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062403.3", "url": "https://www.ensembl.org/id/ENSBTAP00000062403.3" } ] } }, { "isoform_ac": "A0A3Q1N181-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N181/entry", "sequence": { "sequence": "MRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 680, "header": "tr|A0A3Q1N181-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=3 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52700066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068768.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068768.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062718.3", "url": "https://www.ensembl.org/id/ENSBTAP00000062718.3" } ] } }, { "isoform_ac": "A0AAA9RYS5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYS5/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 683, "header": "tr|A0AAA9RYS5-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=1 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126321.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126321.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076284.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076284.1" } ] } }, { "isoform_ac": "A0AAA9RZ05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ05/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 696, "header": "tr|A0AAA9RZ05-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=1 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120602.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120602.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075006.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075006.1" } ] } }, { "isoform_ac": "A0AAA9T1G4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1G4/entry", "sequence": { "sequence": "MGKSKGSHRNMMRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 657, "header": "tr|A0AAA9T1G4-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=1 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52705872, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105010.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105010.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092618.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092618.1" } ] } }, { "isoform_ac": "A0AAA9TVE9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVE9/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGSKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPEILLKNQRNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNESSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 688, "header": "tr|A0AAA9TVE9-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=1 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119396.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119396.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102597.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102597.1" } ] } }, { "isoform_ac": "F6PSE8-1", "url": "https://www.uniprot.org/uniprotkb/F6PSE8/entry", "sequence": { "sequence": "MSNFTLRKTSPTGNDMRTTTQGTTLRQQGFQEVNKRRTFLQDNSWIKKRPEEERDENYGRAVLHRHNSHNALDRKTNEREEPKATISRYRSDDTLDRISNRNDAAKTYKANTLDNRLTNRNVSTFQPPEVTKMQPGGLSSAKATSTPTSTSTTTPVKKKRQSWFPPPPPGYTTTPNTGASRREPTVHPPIPPKPSSTVSSPNQPKQDNRQIYPAKPSVHTEANRSAERNIRSQDLENIVKVATSLQKTNKGEELDNLIKMNKSLNRNQGLDGLFRANLKSELMEKRAKSLENLIFVNTRTDKDGKGNQGLGSLIKVNQRADKIKKGSQDLKEVIKANATTDQTSRGKDLDSIIKVNPKESANTTGKQDLNGLIKVNPETHKNIKRGQSLDNLIQVTPEVNRSNPSSKDLDNLIKVNPRTGESVQGDQSLDNVIRVTPETNKTNQGSQDLDSLIKVTPSAKKSSEQGLDELINVSPKAVKNTARNQDLDKLIKVNPAVIRSNQSQALDNLIQVKPSALRNTKRDQNLENLTDINYNVSKNKNERQDGQVTGSTETLISPSSRTAAYSYEARKMLSSNTETRHAGSKDTVVYTRTYMENSKSPKDGYQETVSGKYIQTVYSTSDRSVIERDMCTYCRKPLGTETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCESCYSKVVAKWIQ", "length": 698, "header": "tr|F6PSE8-1|A0A3Q1LGF4_BOVIN Computationally mapped isoform of Sciellin OS=Bos taurus OX=9913 GN=SCEL PE=1 SV=1 CANONICAL=A0A3Q1LGF4-1" }, "locus": { "chromosome": "12", "start_pos": 52807575, "end_pos": 52699346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046565.5", "url": "https://www.ensembl.org/id/ENSBTAT00000046565.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043851.4", "url": "https://www.ensembl.org/id/ENSBTAP00000043851.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" }, { "name": "keratinocyte differentiation", "id": "GO:0030216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030216", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" }, { "name": "response to mechanical stimulus", "id": "GO:0009612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009612", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { 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"database": "Ensembl Peptide", "id": "ENSBTAP00000057820.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057820.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336907", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGW7" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LGW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGW7" } ], "pmid": "" } ] }, { "name": 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LML6", "url": "https://www.orthodb.org/?gene=A0A3Q1LML6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LR62", "url": "https://www.orthodb.org/?gene=A0A3Q1LR62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N238", "url": "https://www.orthodb.org/?gene=F1N238", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47330", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47330", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47330:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47330:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001346901", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001346901", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGY1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LGY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LML6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LML6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LR62", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LR62-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXH0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXH0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N238", "url": "https://www.uniprot.org/uniprotkb/F1N238", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N238-1", "url": "https://www.uniprot.org/uniprotkb/F1N238-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATATIALQVNGQQGGGSEPAAAAAAAAVVAAGDKWKPPQGTDSIKMENGQGTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 562, "header": "tr|A0A3Q1LML6-1|A0A3Q1LML6_BOVIN Isoform 1 of Poly(U)-binding-splicing factor PUF60 OS=Bos taurus OX=9913 GN=PUF60 PE=3 SV=1 CANONICAL=A0A3Q1LML6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LGY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGY1/entry", "sequence": { "sequence": "MENGQGTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 499, "header": "tr|A0A3Q1LGY1-1|A0A3Q1LML6_BOVIN Computationally mapped isoform of Poly(U)-binding-splicing factor PUF60 OS=Bos taurus OX=9913 GN=PUF60 PE=3 SV=2 CANONICAL=A0A3Q1LML6-1" }, "locus": { "chromosome": "14", "start_pos": 985906, "end_pos": 980767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077344.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077344.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057845.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057845.2" } ] } }, { "isoform_ac": "A0A3Q1LML6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LML6/entry", "sequence": { "sequence": "MATATIALQVNGQQGGGSEPAAAAAAAAVVAAGDKWKPPQGTDSIKMENGQGTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 562, "header": "tr|A0A3Q1LML6-1|A0A3Q1LML6_BOVIN Isoform 1 of Poly(U)-binding-splicing factor PUF60 OS=Bos taurus OX=9913 GN=PUF60 PE=3 SV=1 CANONICAL=A0A3Q1LML6-1" }, "locus": { "chromosome": "14", "start_pos": 985906, "end_pos": 973821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083417.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083417.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061124.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061124.1" } ] } }, { "isoform_ac": "A0A3Q1LR62-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR62/entry", "sequence": { "sequence": "MATATIALGTDSIKMENGQGTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 530, "header": "tr|A0A3Q1LR62-1|A0A3Q1LR62_BOVIN Computationally mapped isoform of Poly(U)-binding-splicing factor PUF60 OS=Bos taurus OX=9913 GN=PUF60 PE=3 SV=1 CANONICAL=A0A3Q1LML6-1" }, "locus": { "chromosome": "14", "start_pos": 985906, "end_pos": 973821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073909.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073909.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059475.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059475.1" } ] } }, { "isoform_ac": "A0ABI0NXH0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXH0/entry", "sequence": { "sequence": "MENGQGTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 516, "header": "tr|A0ABI0NXH0-1|A0ABI0NXH0_BOVIN Computationally mapped isoform of Poly(U)-binding-splicing factor PUF60 OS=Bos taurus OX=9913 GN=PUF60 PE=3 SV=1 CANONICAL=A0A3Q1LML6-1" }, "locus": { "chromosome": "14", "start_pos": 985906, "end_pos": 980767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144288.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144288.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104418.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104418.1" } ] } }, { "isoform_ac": "F1N238-1", "url": "https://www.uniprot.org/uniprotkb/F1N238/entry", "sequence": { "sequence": "SGTGTDSIKMENGQGTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 525, "header": "tr|F1N238-1|A0A3Q1LML6_BOVIN Computationally mapped isoform of Poly(U)-binding-splicing factor PUF60 OS=Bos taurus OX=9913 GN=PUF60 PE=3 SV=3 CANONICAL=A0A3Q1LML6-1" }, "locus": { "chromosome": "14", "start_pos": 985906, "end_pos": 980569, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002882.5", "url": "https://www.ensembl.org/id/ENSBTAT00000002882.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002882.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002882.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 307, "start_aa": "Thr", "end_pos": 307, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr307", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 317, "start_aa": "Thr", "end_pos": 317, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr317", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 353, "start_aa": "Thr", "end_pos": 353, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr353", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:512824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512824", "resource": "KEGG Pathway" }, { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-BTA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-BTA-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480V822-1", "protein_name": "Poly(U)-binding-splicing factor PUF60", "gene_name": "PUF60", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATATIALQVNGQQGGGSEPAAAAAAVAAGDKWKPPQGTDPVKMENGQNTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 559 }, "evidence": [ { "id": "A0A3Q1LML6", "url": "https://omabrowser.org/oma/group/A0A3Q1LML6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QZ57-1", "protein_name": "Poly(U)-binding-splicing factor PUF60a isoform X1", "gene_name": "puf60a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVAVSAVNGGEALMMENGQSTASKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMPNSLQMASLTMGFGDPLSPLQSVAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTLKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHPDLSDDDIKSVFEAFGRIKSCSLARDPTTGKHKGYGFIEYDKAQSAQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQMAWNLSQPENRTEDFLNCLEAVAGASILGAMTAGTGLSMPQLPQAVMAAQAPGVITGVTPARPAMPVVPQVGLVNPVLSSPPTLSAAVAAAQEAKKEKEEEEALLDGLGQEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVGPEDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEVIVKIFVEFSAASEMNKAIQALNNRWFGGRKVIAEVYDQERFDNSDLSA", "length": 552 }, "evidence": [ { "id": "A0A3Q1LML6", "url": "https://omabrowser.org/oma/group/A0A3Q1LML6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UEB3-1", "protein_name": "Poly(U)-binding-splicing factor PUF60", "gene_name": "Puf60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATATIALQVNGQQGGGSEPAAAAAAAAAAVVAAGDKWKPPQGTESIKMENGQSTGTKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSMASETHKAIQALNGRWFGGRKVVAEVYDQERFDNSDLSA", "length": 564 }, "evidence": [ { "id": "A0A3Q1LML6", "url": "https://omabrowser.org/oma/group/A0A3Q1LML6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T6B9-1", "protein_name": "Poly(U)-binding-splicing factor hfp", "gene_name": "hfp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGSNDRASRSPRSDDQREISDMPATKRTRSDSGKSTDSKIPYLSQPLYDLKQTGDVKFGPGTRSALLGLLGGALPKLSSEQHDLVSKAKKYAMEQSIKMVLMKQTLAHQQQQLATQRTQVQRQQALALMCRVYVGSISFELKEDTIRVAFTPFGPIKSINMSWDPITQKHKGFAFVEYEIPEGAQLALEQMNGALMGGRNIKVGRPSNMPQAQQVIDEVQEEAKSFNRIYVASIHPDLSEEDIKSVFEAFGPILYCKLAQGTSLHTHKGYGFIEYANKQAMDEAIASMNLFDLGGQLLRVGRSITPPNALACPTTNSTMPTAAAVAAAAATAKIQALDAVASNAVLGLSQNTPVMAAGAVVTKVGAMPVVSAATSAAALHPALAQAAPALLPPGIFQAPTPVAPSLLGVPAGLQPLQAVVPTLPPPALLATPTLPMTVGGVGVGLVPTVATLAGAEASKGAAAAAALSAAANNAAVTAANLSENIKKAHEKQQEELQKKLMDEGDVQTLQQQENMSIKGQSARQLVMQRLMRPVDSRVIILRNMVGPEDVDETLQEEIQEECSKFGTVSRVIIFNEKQTENEDDDEAEIIVKIFVEFSAGAEAMRGKEALDGRFFGGRRVVAELYDQGIFDQGDLSG", "length": 637 }, "evidence": [ { "id": "A0A3Q1LML6", "url": "https://omabrowser.org/oma/group/A0A3Q1LML6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9UHX1-1", "protein_name": "Poly(U)-binding-splicing factor PUF60", "gene_name": "PUF60", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA", "length": 559 }, "evidence": [ { "id": "A0A3Q1LML6", "url": "https://omabrowser.org/oma/group/A0A3Q1LML6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WV25-1", "protein_name": "Poly(U)-binding-splicing factor PUF60", "gene_name": "Puf60", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377141" }, "gene_names": [ { "name": "OR8J16", "type": "recommended", "evidence": [ { "id": "A0A3Q1LHH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9" } ] }, { "name": "OR8J16", "type": "synonym", "evidence": [ { "id": "NP_001377141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377141" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 8 subfamily J member 16", "type": "synonym", "evidence": [ { "id": "A0A3Q1LHH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8J1", "type": "synonym", "evidence": [ { "id": "NP_001377141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377141" } ] }, { "name": "olfactory receptor family 8 subfamily J member 16", "type": "synonym", "evidence": [ { "id": "NP_001377141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377141" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377141", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377141" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHH9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHH9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8J16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9", "locus": { "chromosome": "15", "start_pos": 79269582, "end_pos": 79268650, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000061445", "url": "https://www.ensembl.org/id/ENSBTAG00000061445" } ] } } ], "crossref": [ { "id": "A0A3Q1LHH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LHH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "615824", "url": "https://www.ncbi.nlm.nih.gov/gene/615824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615824", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615824", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLYMEVV", "url": "https://omabrowser.org/oma/group/LLYMEVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LHH9", "url": "https://www.orthodb.org/?gene=A0A3Q1LHH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377141", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377141", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHH9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANGNFTQVIEFILIGVSERPDLQIPLFFVFLVIYGLTVTGNLSIITLTSVDSQLQTPMYFFLRHLAMINLGNSTVIAPKMLINFLVKKHTTSFYECAIQLGGFLVFIVAEIFMLAVMAYDHYVAICNPLLYMVVVSRRVCFLLVSLTYLYSFSTSIVTSFSVFSMAYCSFNVINHFYCDIVPLLALSCSNTSFPETVVFISASTNLMFSITVVVTSYFNIILSILRICSSEGRKRAFSTCASHMTAVSVFYGTLLFMYLQPRNNHSLETDKMASAFYTLVIPMLNPMIYSLRNKDMKAALKRFLTNSCC", "length": 310, "header": "tr|A0A3Q1LHH9-1|A0A3Q1LHH9_BOVIN Isoform 1 of Olfactory receptor family 8 subfamily J member 16 OS=Bos taurus OX=9913 GN=OR8J16 PE=3 SV=1 CANONICAL=A0A3Q1LHH9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHH9/entry", "sequence": { "sequence": 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"A0A3Q1LHP2_BOVIN", "mass": { "chemical_mass": 60390.0, "monoisotopic_mass": 60390.0 }, "refseq": {}, "gene_names": [ { "name": "SCHIP1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2" } ] } ], "protein_names": [ { "name": "Schwannomin interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SCHIP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2", "locus": { "chromosome": "1", "start_pos": 107552331, "end_pos": 107700466, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014960", "url": "https://www.ensembl.org/id/ENSBTAG00000014960" } ] } } ], "crossref": [ { "id": "A0A3Q1LHP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LHP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014960", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014960", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535716", "url": "https://www.ncbi.nlm.nih.gov/gene/535716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LHP2", "url": "https://www.orthodb.org/?gene=A0A3Q1LHP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13103:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13103:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LHP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PRG8", "url": "https://www.uniprot.org/uniprotkb/F6PRG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PRG8-1", "url": "https://www.uniprot.org/uniprotkb/F6PRG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDTSPICTPLFLIHTPLIGHSQRAARKGKKTCAKATGSTHSLNLEGEAGARRQELGGGGRGSGEEEGGREMMVHDHGAHVTRAPTWACDYREDGMDLGSDAGSSSSNSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGEEKEEEDGRHERGYRDDRCPAREPGDVSARTRSGGGRSATTAMPPPVPNGNLHPQEPQDLRHNGNVVVAGRPSGSRAPRRAVQKPQPAGGRRGGRGPAARGLCLQPTDSGTCVPEEPPVPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSSRLQSGMNLQICFVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHLPHISECLMKRSLKPTDLRDMTLGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHLAEKMPAK", "length": 554, "header": "tr|A0A3Q1LHP2-1|A0A3Q1LHP2_BOVIN Isoform 1 of Schwannomin interacting protein 1 OS=Bos taurus OX=9913 GN=SCHIP1 PE=4 SV=2 CANONICAL=A0A3Q1LHP2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2/entry", "sequence": { "sequence": "MPDTSPICTPLFLIHTPLIGHSQRAARKGKKTCAKATGSTHSLNLEGEAGARRQELGGGGRGSGEEEGGREMMVHDHGAHVTRAPTWACDYREDGMDLGSDAGSSSSNSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGEEKEEEDGRHERGYRDDRCPAREPGDVSARTRSGGGRSATTAMPPPVPNGNLHPQEPQDLRHNGNVVVAGRPSGSRAPRRAVQKPQPAGGRRGGRGPAARGLCLQPTDSGTCVPEEPPVPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSSRLQSGMNLQICFVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHLPHISECLMKRSLKPTDLRDMTLGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHLAEKMPAK", "length": 554, "header": "tr|A0A3Q1LHP2-1|A0A3Q1LHP2_BOVIN Isoform 1 of Schwannomin interacting protein 1 OS=Bos taurus OX=9913 GN=SCHIP1 PE=4 SV=2 CANONICAL=A0A3Q1LHP2-1" }, "locus": { "chromosome": "1", "start_pos": 107700385, "end_pos": 107552918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082405.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082405.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058302.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058302.2" } ] } }, { "isoform_ac": "F6PRG8-1", "url": "https://www.uniprot.org/uniprotkb/F6PRG8/entry", "sequence": { "sequence": "MVHQENCSYQAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSSRLQSGMNLQICFVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHLPHISECLMKRSLKPTDLRDMTLGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHLAEKMPAK", "length": 244, "header": "tr|F6PRG8-1|A0A3Q1LHP2_BOVIN Computationally mapped isoform of Schwannomin interacting protein 1 OS=Bos taurus OX=9913 GN=SCHIP1 PE=4 SV=1 CANONICAL=A0A3Q1LHP2-1" }, "locus": { "chromosome": "1", "start_pos": 107614638, "end_pos": 107552918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031972.6", "url": "https://www.ensembl.org/id/ENSBTAT00000031972.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031917.5", "url": "https://www.ensembl.org/id/ENSBTAP00000031917.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHP2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LHP2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 554, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LHP2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LHP2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LHP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHP2" }, { "id": "PF10148", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10148" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Schwannomin interacting protein 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 551, "start_aa": "Gln", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 117, "end_pos": 119 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 373, "end_pos": 375 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LHS4-1", "uniprot_ac": "A0A3Q1LHS4", "uniprot_id": "A0A3Q1LHS4_BOVIN", "mass": { "chemical_mass": 34793.0, "monoisotopic_mass": 34793.0 }, "refseq": {}, "gene_names": [ { "name": "OR9S36", "type": "recommended", "evidence": [ { "id": "A0A3Q1LHS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4" } ] }, { "name": "OR9S29", "type": "synonym", "evidence": [ { "id": "A0A3Q1LHS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LHS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR9S36", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4", "locus": { "chromosome": "3", "start_pos": 119621371, "end_pos": 119620421, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000065755", "url": "https://www.ensembl.org/id/ENSBTAG00000065755" } ] } } ], "crossref": [ { "id": "A0A3Q1LHS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LHS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15419", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15419", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:112445898", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112445898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LHS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPHRNGNLSVMPLQEFVLDGFEGGLQTQALLFALFLVLYVVAILGNLIMMVVITLDARLHSPMYFFLKNLSLVDLCYSSVIAPKALANFLSSSKVITFEGCATQFFLFSMLVTTEGFLLAVMAYDRFMAICSPLRYPISMCPSVCARLMLGCYSGGCLNSILQTSFTFSLPFCSSNHIDHFFCDVPPLLKLACADTTINELLLFGICGLIIMGTILVIVISYSYITVTILRMHSGGGRHKLLSTCGSHMTAVSLLYGTVFVMYAQPGAVQSMEQGKVVSVFYTLVIPMLNPLIYSLRNKDVKDALWRLGQKHTAT", "length": 316, "header": "tr|A0A3Q1LHS4-1|A0A3Q1LHS4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR9S36 PE=3 SV=2 CANONICAL=A0A3Q1LHS4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4/entry", "sequence": { "sequence": "MSPHRNGNLSVMPLQEFVLDGFEGGLQTQALLFALFLVLYVVAILGNLIMMVVITLDARLHSPMYFFLKNLSLVDLCYSSVIAPKALANFLSSSKVITFEGCATQFFLFSMLVTTEGFLLAVMAYDRFMAICSPLRYPISMCPSVCARLMLGCYSGGCLNSILQTSFTFSLPFCSSNHIDHFFCDVPPLLKLACADTTINELLLFGICGLIIMGTILVIVISYSYITVTILRMHSGGGRHKLLSTCGSHMTAVSLLYGTVFVMYAQPGAVQSMEQGKVVSVFYTLVIPMLNPLIYSLRNKDVKDALWRLGQKHTAT", "length": 316, "header": "tr|A0A3Q1LHS4-1|A0A3Q1LHS4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR9S36 PE=3 SV=2 CANONICAL=A0A3Q1LHS4-1" }, "locus": { "chromosome": "3", "start_pos": 119016596, "end_pos": 119015649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071016.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071016.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058369.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058369.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:112445898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112445898", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 295, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVIKSLLYMRIVPLLHWLGVFLFFTGHTRAENFQYHSPPEVVIPLKITGTRRSMKPPGRLSYSLHLGGQRHVFHMKVKKHLLSRHLPVFTYSEEGALLKDQPFVQNDCYYHGFVEGDPESLVALSTCLGGFRGLLQINNVVYEIKPMIFSTKFEHLVYKMESEETRFPTMKSGFVQEESVEHFEFQETGNCTLKQSHYEGWWIHSFFVEMAVVVDYTLYNYFKKNVSKVKEDLFTIVNIVDSIYQVMGMKVLLIGLEFWTQRNLVEIDAVQRALRDFCVWKANNIDARIAHDTTHIFMQKTLRGLSGIGFIAGMCRPHFSCAAVTFANKTLAIIGIAVAHHLGHNLGMTHDTILCVCSAGHNRCIMRHDNPPIAKFSNCSYSFFWEYGVQKAKCLRYTIYTKDIFSRKRCGNGVVEEGEECDCGSLQQCSRDACCLTNCSLSFGSVCAFGLCCKDCKFLPSGEMCRKEVNECDLPEWCNGSSHMCPDDVYVEDGIPCNDISYCYEKRCNDRNAHCRQIFGRTAKNANDSCYRQINTQGDRFGNCGTEGPTYLKCNMSDIFCGRIQCDNVAEIPLLTEHSTMHGTRFNNATCWGTDYHFGMDIPDIGEVKDGTECGPEHVCIGRKCVHISRLDSNCSPTFCNMRGICNNKHHCHCNYKWDPPNCVKRGDGGSVDSGPPPKRKKIPKIYVAIALFISLLILLCCLLLLSEPQFINTTSSLQAPARAVTATSSSS", "length": 733, "header": "tr|A0A3Q1LHS9-1|A0A3Q1LHS9_BOVIN Isoform 1 of ADAM metallopeptidase domain 29 OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=A0A3Q1LHS9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHS9-1", "url": 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"chromosome": "8", "start_pos": 7260888, "end_pos": 7232888, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070344.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070344.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058380.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058380.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9" } ], "pmid": "" }, { "name": "sperm head plasma membrane", "id": "GO:1990913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990913", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LHS9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": 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"tr|A0A3Q1LI03-1|A0A3Q1LI03_BOVIN Isoform 1 of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP11 PE=3 SV=1 CANONICAL=A0A3Q1LI03-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LI03-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI03/entry", "sequence": { "sequence": "MTLRPSLLPLRLLLLLLLLRGAVCQAEAGSETESPVRTLQVETLVEPPEPCAEPATFGDTLHIHYSGSLVDGRIFDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRVIIPSHLAYGKRGFPPSIPADAELHFDVELIALIRANYWQKLVKGILPLVGMAMVPALLGLIGYHLYRKASSPKISKKKLKEEKRNKSKKK", "length": 202, "header": "tr|A0A3Q1LI03-1|A0A3Q1LI03_BOVIN Isoform 1 of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP11 PE=3 SV=1 CANONICAL=A0A3Q1LI03-1" }, "locus": { "chromosome": "5", "start_pos": 30884818, "end_pos": 30881465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067323.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067323.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058519.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058519.1" } ] } }, { "isoform_ac": "A0A3Q1M396-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M396/entry", "sequence": { "sequence": "MTLRPSLLPLRLLLLLLLLRGAVCQAEAGSETESPVRTLQVETLVEPPEPCAEPATFGDTLHIHYSGSLVDGRIFDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRVIIPSHLAYGKRGFPPSIPGTRDNLLKPPGLSSGSRP", "length": 148, "header": "tr|A0A3Q1M396-1|A0A3Q1M396_BOVIN Computationally mapped isoform of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP11 PE=3 SV=2 CANONICAL=A0A3Q1LI03-1" }, "locus": { "chromosome": "5", "start_pos": 30883420, "end_pos": 30881465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077430.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077430.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062623.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062623.2" } ] } }, { "isoform_ac": "F1MT51-1", "url": "https://www.uniprot.org/uniprotkb/F1MT51/entry", "sequence": { "sequence": "MTLRPSLLPLRLLLLLLLLRGAVCQAEAGSETESPVRTLQVETLVEPPEPCAEPATFGDTLHIHYSGSLVDGRIFDTSLTRDPLVIELGQKQVIPGTEKRRVIIPSHLAYGKRGFPPSIPADAELHFDVELIALIRANYWQKLVKGILPLVGMAMVPALLGLIGYHLYRKASSPKISKKKLKEEKRNKSKKK", "length": 192, "header": "tr|F1MT51-1|F1MT51_BOVIN Computationally mapped isoform of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP11 PE=3 SV=2 CANONICAL=A0A3Q1LI03-1" }, "locus": { "chromosome": "5", "start_pos": 30884818, "end_pos": 30881465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021025.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021025.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021025.4", "url": "https://www.ensembl.org/id/ENSBTAP00000021025.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FAH4-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "Fkbp11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLRPLLWPLRLLLLLLFSGVVCWAEVGPETESPVRTLQVETLVQPPESCTESAAFGDTLHIHYTGSLVDGRIIDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRAVIPSHLAYGKRGYPPSIPASPVDAVVQLLTLPLPSASPADAVVQYDVELIALIRANYWQKLLKGILPLVGMAMVPALLGLIGYHLYKKSSRTKVSKKKLKEEKRNKSKKK", "length": 221 }, "evidence": [ { "id": "A0A3Q1LI03", "url": "https://omabrowser.org/oma/group/A0A3Q1LI03/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P61206-1", "protein_name": "ADP-ribosylation factor 3", "gene_name": "Arf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK", "length": 181 }, "evidence": [ { "id": "A0A3Q1LI03", "url": "https://omabrowser.org/oma/group/A0A3Q1LI03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D1M7-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP11", "gene_name": "Fkbp11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLSPLLLPLQLLLLLLFSGAVCRAEAGPETESPVRTLQVETLVQPPESCTESAAIGDTLHIHYTGSLVDGRIIDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRAVIPSHLAYGKRGYPPSIPADAVVQYDVELIALIRANYWQKLLKSILPLVGIAMVPALLGLIGYHLYRKASRPKVSKKKLKEEKRNKSKKK", "length": 201 }, "evidence": [ { "id": "A0A3Q1LI03", "url": "https://omabrowser.org/oma/group/A0A3Q1LI03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYL4-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP11", "gene_name": "FKBP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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[] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LJ78-1", "uniprot_ac": "A0A3Q1LJ78", "uniprot_id": "A0A3Q1LJ78_BOVIN", "mass": { "chemical_mass": 58658.0, "monoisotopic_mass": 58658.0 }, "refseq": {}, "gene_names": [ { "name": "LPGAT1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78" } ] } ], "protein_names": [ { "name": "Lysophosphatidylglycerol acyltransferase 1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJ78", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LPGAT1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78", "locus": { "chromosome": "16", "start_pos": 71720055, "end_pos": 71591831, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005137", "url": "https://www.ensembl.org/id/ENSBTAG00000005137" } ] } } ], "crossref": [ { "id": "A0A3Q1LJ78", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LJ78", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005137", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005137", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "541208", "url": "https://www.ncbi.nlm.nih.gov/gene/541208", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LJ78", "url": "https://www.orthodb.org/?gene=A0A3Q1LJ78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10983", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10983", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10983:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10983:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LJ78", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAX5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MWR5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MWR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STM0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DMF0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DMF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGIKPSWVSWLNHFKMSGDSWKCKKSYFSFKGSSSCGSNLFRAFTHLSACGIVEITYRNISGGCISSREGSRAPSRPLAPHLGRRRRRVHDRDPPAEDTRRRRRAPGRPPPAPPVPALYRPPPAPAEQDRTDFDVRMAVTLEEAPWLGWILVKALVRFAFMVANNLVAIPSYLCYIIVLLPLRLLDSKRYWYLEGMMYKWLLGMVASWGWYAGYTVMEWGEDIKTISEDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGKSHRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQSFAKKNNLPFLTHVTLPRVGATKIILRALVARQENGSPAGGDAKELDNKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPAVIHVHYRIFPVKDVPLETDDLSDWLYQRFIEKEDLLSHFYETGAFPPPKGHKEAVSREMTLSNMWIFLIQSFAFLSGYMWYNIFQYFYHCLF", "length": 507, "header": "tr|A0A3Q1LJ78-1|A0A3Q1LJ78_BOVIN Isoform 1 of Lysophosphatidylglycerol acyltransferase 1 OS=Bos taurus OX=9913 GN=LPGAT1 PE=3 SV=2 CANONICAL=A0A3Q1LJ78-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78/entry", "sequence": { "sequence": "MDGIKPSWVSWLNHFKMSGDSWKCKKSYFSFKGSSSCGSNLFRAFTHLSACGIVEITYRNISGGCISSREGSRAPSRPLAPHLGRRRRRVHDRDPPAEDTRRRRRAPGRPPPAPPVPALYRPPPAPAEQDRTDFDVRMAVTLEEAPWLGWILVKALVRFAFMVANNLVAIPSYLCYIIVLLPLRLLDSKRYWYLEGMMYKWLLGMVASWGWYAGYTVMEWGEDIKTISEDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGKSHRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQSFAKKNNLPFLTHVTLPRVGATKIILRALVARQENGSPAGGDAKELDNKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPAVIHVHYRIFPVKDVPLETDDLSDWLYQRFIEKEDLLSHFYETGAFPPPKGHKEAVSREMTLSNMWIFLIQSFAFLSGYMWYNIFQYFYHCLF", "length": 507, "header": "tr|A0A3Q1LJ78-1|A0A3Q1LJ78_BOVIN Isoform 1 of Lysophosphatidylglycerol acyltransferase 1 OS=Bos taurus OX=9913 GN=LPGAT1 PE=3 SV=2 CANONICAL=A0A3Q1LJ78-1" }, "locus": { "chromosome": "16", "start_pos": 71713505, "end_pos": 71629897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071102.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071102.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059374.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059374.2" } ] } }, { "isoform_ac": "A0A3Q1MAX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAX5/entry", "sequence": { "sequence": "MDGIKPSWVSWLNHFKMSGDSWKCKKSYFSFKGSSSCGSNQDRTDFDVRMAVTLEEAPWLGWILVKALVRFAFMVANNLVAIPSYLCYIIVLLPLRLLDSKRYWYLEGMMYKWLLGMVASWGWYAGYTVMEWGEDIKTISEDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGKSHRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQSFAKKNNLPFLTHVTLPRVGATKIILRALVARQENGSPAGGDAKELDNKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPAVIHVHYRIFPVKDVPLETDDLSDWLYQRFIEKEDLLSHFYETGAFPPPKGHKEAVSREMTLSNMWIFLIQSFAFLSGYMWYNIFQYFYHCLF", "length": 419, "header": "tr|A0A3Q1MAX5-1|A0A3Q1LJ78_BOVIN Computationally mapped isoform of Lysophosphatidylglycerol acyltransferase 1 OS=Bos taurus OX=9913 GN=LPGAT1 PE=3 SV=1 CANONICAL=A0A3Q1LJ78-1" }, "locus": { "chromosome": "16", "start_pos": 71713505, "end_pos": 71629897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072432.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072432.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065780.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065780.2" } ] } }, { "isoform_ac": "A0A3Q1MWR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWR5/entry", "sequence": { "sequence": "MTWSAETLPKPHQDRTDFDVRMAVTLEEAPWLGWILVKALVRFAFMVANNLVAIPSYLCYIIVLLPLRLLDSKRYWYLEGMMYKWLLGMVASWGWYAGYTVMEWGEDIKTISEDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGKSHRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQSFAKKNNLPFLTHVTLPRVGATKIILRALVARQENGSPAGGDAKELDNKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPAVIHVHYRIFPVKDVPLETDDLSDWLYQRFIEKEDLLSHFYETGAFPPPKGHKEAVSREMTLSNMWIFLIQSFAFLSGYMWYNIFQYFYHCLF", "length": 391, "header": "tr|A0A3Q1MWR5-1|A0A3Q1LJ78_BOVIN Computationally mapped isoform of Lysophosphatidylglycerol acyltransferase 1 OS=Bos taurus OX=9913 GN=LPGAT1 PE=3 SV=1 CANONICAL=A0A3Q1LJ78-1" }, "locus": { "chromosome": "16", "start_pos": 71713505, "end_pos": 71622400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076220.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076220.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060004.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060004.2" } ] } }, { "isoform_ac": "A0AAA9ST88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST88/entry", "sequence": { "sequence": "MAVTLEEAPWLGWILVKALVRFAFMVANNLVAIPSYLCYIIVLLPLRLLDSKRYWYLEGMMYKWLLGMVASWGWYAGYTVMEWGEDIKTISEDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGKSHRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQSFAKKNNLPFLTHVTLPRVGATKIILRALVARQENGSPAGGDAKELDNKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPAVIHVHYRIFPVKDVPLETDDLSDWLYQRFIEKEDLLSHFYETGAFPPPKGHKEAVSREMTLSNMWIFLIQSFAFLSGYM", "length": 357, "header": "tr|A0AAA9ST88-1|A0A3Q1LJ78_BOVIN Computationally mapped isoform of Lysophosphatidylglycerol acyltransferase 1 OS=Bos taurus OX=9913 GN=LPGAT1 PE=3 SV=1 CANONICAL=A0A3Q1LJ78-1" }, "locus": { "chromosome": "16", "start_pos": 71713468, "end_pos": 71635934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093089.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093089.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087348.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087348.1" } ] } }, { "isoform_ac": "A0AAA9STM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STM0/entry", "sequence": { "sequence": "MAVTLEEAPWLGWILVKALVRFAFMVANNLVAIPSYLCYIIVLLPLRLLDSKRYWYLEGMMYKWLLGMVASWGWYAGYTVMEWGEDIKTISEDEAVMLVNHQATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGKSHRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQSFAKKNNLPFLTHVTLPRVGATKIILRALVARQENGSPAGGDAKELDNKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPAVIHVHYRIFPVKDVPLETDDLSDWLYQRFIEKEDLLSHFYETGCCSGEAVVSRRVVSVEDEQTEDRALKASVKNSEIYCGPALFFMSWEQKKIHCF", "length": 374, "header": "tr|A0AAA9STM0-1|A0A3Q1LJ78_BOVIN Computationally mapped isoform of Lysophosphatidylglycerol acyltransferase 1 OS=Bos taurus OX=9913 GN=LPGAT1 PE=3 SV=1 CANONICAL=A0A3Q1LJ78-1" }, "locus": { "chromosome": "16", "start_pos": 71719877, "end_pos": 71635934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110389.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110389.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087482.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087482.1" } ] } }, { "isoform_ac": "A0AAF6DMF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMF0/entry", "sequence": { "sequence": "MAVTLEEAPWLGWILVKALVRFAFMVANNLVAIPSYLCYIIVLLPLRLLDSKRYWYLEGMMYKWLLGMVASWGWYAGYTVMEWGEDIKTISEDEAVMLVNHQATGDVCTLMMCLQDKGLGKSHRDQQLLLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQSFAKKNNLPFLTHVTLPRVGATKIILRALVARQENGSPAGGDAKELDNKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPAVIHVHYRIFPVKDVPLETDDLSDWLYQRFIEKEDLLSHFYETGAFPPPKGHKEAVSREMTLSNMWIFLIQSFAFLSGYMWYNIFQYFYHCLF", "length": 338, "header": "tr|A0AAF6DMF0-1|A0A3Q1LJ78_BOVIN Computationally mapped isoform of Lysophosphatidylglycerol acyltransferase 1 OS=Bos taurus OX=9913 GN=LPGAT1 PE=3 SV=1 CANONICAL=A0A3Q1LJ78-1" }, "locus": { "chromosome": "16", "start_pos": 71713505, "end_pos": 71635934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006773.6", "url": "https://www.ensembl.org/id/ENSBTAT00000006773.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006773.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006773.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJ78", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ78" } 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16029:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22060", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22060", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22065", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22065", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22074", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22074", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010817274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T737", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T737", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T737-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T737-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE37", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE37-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSQ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAX3", "url": "https://www.uniprot.org/uniprotkb/F1MAX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAX3-1", "url": "https://www.uniprot.org/uniprotkb/F1MAX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVFSLAVSILRSLDWSFSCSKINFFSGLQFLGQTLSEMEDFRGIAEESFPSFLTSSLLGNSGILENVTLSSNLGLPVAVSTLARNRSSSENRYSDVQTSYLVEGKFSVPSETSPSSQSEDEPRERLRLVFSDDDSLAKKKNQTENQCLSDAVLRESAFPSDGARAEEEQARAAEPFLNQGPSNRASPLGQEQDSPIDFCSQSWMNKENKIGVPDVGKHFEKRNPNSDLSLTSFLENEKLISLASLEDSSDDDIDDEEFYDDHLEAYFEQLAIPGMMYEDLEGQEPPENYFKLPTSDPSQESGRAEVLVKSLRTPNTKLNPIDFNDTNASKDDFDLMDSLKLEEVSPHQNKHLTSDSETVLPVDRFLDTEMPQVSIQTNVDVASLKPVSDNAFNSTDAPWSPTSERQTCECYELVGKTKDQADPPQSVVYQDEEGRWVTDLAYYTPFDKEQDFNVSLSNELSEDFRSGSDALDLIAQDEEEFNKEHQFMQEENIDAQNMSVALGDTSWGTSVNCGLLRRSLSASDVDRDDASYLRLSLGEFFAQRSEALGCLGGGYNVKRPSFGYFIRSPEKREPIALIRKSDLSRSNLGKEVADLNHGLFSGDLKAQLSEGSVTLQAEELESISQVDENDVTLTANKGKAEDTFLVSSKPQRHTDELPSESDSVLRISTIASAIAEASVSADPLQLATMIKALSNKTREKTCQEDGKQRHYSAVSHFLPNDLEKSNGSSTFDMERYLKKTDISQYEGGLDNFSRAGVSGIWDLSLSKERTTHNIHVVDLGATSISVREPEVGTAAGFYGESGDSVDQASLRTISSSNSVLTNVGEREGTAVDVKTHSIDHKSPDSGDGEKAASVPIPASDSCSVIGNPRVASLWLSEECKGLQESRDYQRQNECIGETSNSEKHVAFENHSIISPKRVDLKSPSPERGGQGSENGEDSFRPSTSPLSHSSPSEISGTSLSGCALESFGSAAQPQKGPCERELSQLTCPEASVSRLTYVSEQESISPSMASRRVLDDRKSDITSELSTTIIRASPVPAQEPAADKLGEKSPFQSRGKGALSYIIQKNLDTEKVTETTSLSSRPEDVKLDFSSSRLPSSKSEDRSQTSATGLTSDRGDLEQVSLALRSESSLHPATLAIPCLPVSRQAPVLDGGHVTPRDTSATDSEFSGQGPYRTSVPSVPSTEGCGPAPMRQHMPLTGPAVSVHYPLPVAPSAQPHSGALPAASSATLPRCRACGATACGLSCGLPGSCHPAVVGEHVQHSVTAGLCLGQDIGSGLMASSSLCNLYSDTLSQNLLNAAKVLPVQSLHPDCGIEPWDSAVVSGLGRVSVPEELKFPHACCVGIASQTYLSVLNPADRWLQVSIGVLSVSVDGEKVDFSAYPCLVFKNRVIIRPHATEEIKVLFIPSDPGIFRCIFSVASWPFSADAETVAQAEALASRVVLTAIAETPMIEVETEKKGVLDFGDLTYGSWKALPLKLVNKTHANIPIRLIISANAVAWRCFTFSKEPIHAALRALPYAHAIAQLAAPSVINHMMPASDDGQDPEFLVIWVLFHSPKKQITSSEILDSAEEFLARVDIEVDSPNPTPVIKSISLRARTGIARIHAPKDLQTLHLFASVASSARQYLPLKNAGNIDVHLDIKIPDQGSHFSVDPEKLFLKPGEEHEVIVSFSPKDPMGCEERILKIFVQPFGPQYEVMLKGEIVSSGNRPLAPESLTSDIPSILSNKQFLAWGGVPLGRTQLQKLALRNNSASTAQHLRLLVRGQDQDCFQLQHTFGSEERLTSNCEVRIRPKEDIYISVLFAPTRLSCMLAKLEIKQLGVRSQPGVKFTIPLSGYGGTSNLILEDVKKLSDSYMVTVNDLVPGQESRIVISVRNTGSRAAFVKAVGFKDSQKKVLLDPKVLRIFPDKFVLKERTQEDVTIIYNPSDRESSCKTTTELSTIYFFGGDEISRQQYRRAVLHMPEVRERVLPSLSVLHSIDFAEAFQDELLVTEVYDLPQQPNDVQLFYGNMRKIILSVIGEFRDSISSREFLPPSAKPSLEFKSESGSCGAHGGNISLDVLPVKGPQGSPLLSQAVPPPQDNSASEEVWAVHPEHLVLVAPSCDMAKTGRFQILNNSIRLLKFELYWPAHCLTVTPQHGFIAPESKMQILVSPNSSLSTKHSMFPWSGLIYIHCDNGQKKIVKVQIREDLTQEELFTHLTSGPLGILSQETEHVVNLVKPAAKPPSTKVELRNKTVTFPPTEPGETSGNYLELENHGDTEVRWHLSSLAPPYVKGVDESGDVFRATYAAFRCSPISGVVEGHSVQKVSIMFLPRDRGDYAQFWDVECHPLKEPHLKHTLRFQLSGHSVRAESEPGISRISANSLIKIDNLLKLRRQAVSEASALIPGRQLDLTHRGVYAPEDVYQFLPTRVGESRTLKVNLRNNSFITHSLKFLSPREPFYVKHSKYSLRAQHYINMPVQFKPKSVGKFEDLLVVQTDEGKSVAVRLTGEALGNIS", "length": 2493, "header": "tr|A0A3Q1LJH6-1|A0A3Q1LJH6_BOVIN Isoform 1 of Centrosomal protein 192 OS=Bos taurus OX=9913 GN=CEP192 PE=4 SV=3 CANONICAL=A0A3Q1LJH6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6/entry", "sequence": { "sequence": "MTVFSLAVSILRSLDWSFSCSKINFFSGLQFLGQTLSEMEDFRGIAEESFPSFLTSSLLGNSGILENVTLSSNLGLPVAVSTLARNRSSSENRYSDVQTSYLVEGKFSVPSETSPSSQSEDEPRERLRLVFSDDDSLAKKKNQTENQCLSDAVLRESAFPSDGARAEEEQARAAEPFLNQGPSNRASPLGQEQDSPIDFCSQSWMNKENKIGVPDVGKHFEKRNPNSDLSLTSFLENEKLISLASLEDSSDDDIDDEEFYDDHLEAYFEQLAIPGMMYEDLEGQEPPENYFKLPTSDPSQESGRAEVLVKSLRTPNTKLNPIDFNDTNASKDDFDLMDSLKLEEVSPHQNKHLTSDSETVLPVDRFLDTEMPQVSIQTNVDVASLKPVSDNAFNSTDAPWSPTSERQTCECYELVGKTKDQADPPQSVVYQDEEGRWVTDLAYYTPFDKEQDFNVSLSNELSEDFRSGSDALDLIAQDEEEFNKEHQFMQEENIDAQNMSVALGDTSWGTSVNCGLLRRSLSASDVDRDDASYLRLSLGEFFAQRSEALGCLGGGYNVKRPSFGYFIRSPEKREPIALIRKSDLSRSNLGKEVADLNHGLFSGDLKAQLSEGSVTLQAEELESISQVDENDVTLTANKGKAEDTFLVSSKPQRHTDELPSESDSVLRISTIASAIAEASVSADPLQLATMIKALSNKTREKTCQEDGKQRHYSAVSHFLPNDLEKSNGSSTFDMERYLKKTDISQYEGGLDNFSRAGVSGIWDLSLSKERTTHNIHVVDLGATSISVREPEVGTAAGFYGESGDSVDQASLRTISSSNSVLTNVGEREGTAVDVKTHSIDHKSPDSGDGEKAASVPIPASDSCSVIGNPRVASLWLSEECKGLQESRDYQRQNECIGETSNSEKHVAFENHSIISPKRVDLKSPSPERGGQGSENGEDSFRPSTSPLSHSSPSEISGTSLSGCALESFGSAAQPQKGPCERELSQLTCPEASVSRLTYVSEQESISPSMASRRVLDDRKSDITSELSTTIIRASPVPAQEPAADKLGEKSPFQSRGKGALSYIIQKNLDTEKVTETTSLSSRPEDVKLDFSSSRLPSSKSEDRSQTSATGLTSDRGDLEQVSLALRSESSLHPATLAIPCLPVSRQAPVLDGGHVTPRDTSATDSEFSGQGPYRTSVPSVPSTEGCGPAPMRQHMPLTGPAVSVHYPLPVAPSAQPHSGALPAASSATLPRCRACGATACGLSCGLPGSCHPAVVGEHVQHSVTAGLCLGQDIGSGLMASSSLCNLYSDTLSQNLLNAAKVLPVQSLHPDCGIEPWDSAVVSGLGRVSVPEELKFPHACCVGIASQTYLSVLNPADRWLQVSIGVLSVSVDGEKVDFSAYPCLVFKNRVIIRPHATEEIKVLFIPSDPGIFRCIFSVASWPFSADAETVAQAEALASRVVLTAIAETPMIEVETEKKGVLDFGDLTYGSWKALPLKLVNKTHANIPIRLIISANAVAWRCFTFSKEPIHAALRALPYAHAIAQLAAPSVINHMMPASDDGQDPEFLVIWVLFHSPKKQITSSEILDSAEEFLARVDIEVDSPNPTPVIKSISLRARTGIARIHAPKDLQTLHLFASVASSARQYLPLKNAGNIDVHLDIKIPDQGSHFSVDPEKLFLKPGEEHEVIVSFSPKDPMGCEERILKIFVQPFGPQYEVMLKGEIVSSGNRPLAPESLTSDIPSILSNKQFLAWGGVPLGRTQLQKLALRNNSASTAQHLRLLVRGQDQDCFQLQHTFGSEERLTSNCEVRIRPKEDIYISVLFAPTRLSCMLAKLEIKQLGVRSQPGVKFTIPLSGYGGTSNLILEDVKKLSDSYMVTVNDLVPGQESRIVISVRNTGSRAAFVKAVGFKDSQKKVLLDPKVLRIFPDKFVLKERTQEDVTIIYNPSDRESSCKTTTELSTIYFFGGDEISRQQYRRAVLHMPEVRERVLPSLSVLHSIDFAEAFQDELLVTEVYDLPQQPNDVQLFYGNMRKIILSVIGEFRDSISSREFLPPSAKPSLEFKSESGSCGAHGGNISLDVLPVKGPQGSPLLSQAVPPPQDNSASEEVWAVHPEHLVLVAPSCDMAKTGRFQILNNSIRLLKFELYWPAHCLTVTPQHGFIAPESKMQILVSPNSSLSTKHSMFPWSGLIYIHCDNGQKKIVKVQIREDLTQEELFTHLTSGPLGILSQETEHVVNLVKPAAKPPSTKVELRNKTVTFPPTEPGETSGNYLELENHGDTEVRWHLSSLAPPYVKGVDESGDVFRATYAAFRCSPISGVVEGHSVQKVSIMFLPRDRGDYAQFWDVECHPLKEPHLKHTLRFQLSGHSVRAESEPGISRISANSLIKIDNLLKLRRQAVSEASALIPGRQLDLTHRGVYAPEDVYQFLPTRVGESRTLKVNLRNNSFITHSLKFLSPREPFYVKHSKYSLRAQHYINMPVQFKPKSVGKFEDLLVVQTDEGKSVAVRLTGEALGNIS", "length": 2493, "header": "tr|A0A3Q1LJH6-1|A0A3Q1LJH6_BOVIN Isoform 1 of Centrosomal protein 192 OS=Bos taurus OX=9913 GN=CEP192 PE=4 SV=3 CANONICAL=A0A3Q1LJH6-1" }, "locus": { "chromosome": "24", "start_pos": 43293240, "end_pos": 43219979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081495.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081495.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059577.3", "url": "https://www.ensembl.org/id/ENSBTAP00000059577.3" } ] } }, { "isoform_ac": "A0AAA9T737-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T737/entry", "sequence": { "sequence": "MTVFSLAVSILRSLDWSFSCSKINFFSGLQFLGQTLSEMEDFRGIAEESFPSFLTSSLLGNSGILENVTLSSNLGLPVAVSTLARNRSSSENRYSDVQTSYLVEGKFSVPSETSPSSQSEDEPRERLRLVFSDDDSLAKKKNQTENQCLSDAVLRESAFPSDGARAEEEQARAAEPFLNQGPSNRASPLGQEQDSPIDFCSQSWMNKENKIGVPDVGKHFEKRNPNSDLSLTSFLENEKLISLASLEDSSDDDIDDEEFYDDHLEAYFEQLAIPGMMYEDLEGQEPPENYFKLPTSDPSQESGRAEVLVKSLRTPNTKLNPIDFNDTNASKDDFDLMDSLKLEEVSPHQNKHLTSDSETVLPVDRFLDTEMPQVSIQTNVDVASLKPVSDNAFNSTDAPWSPTSERQTCECYELVGKTKDQADPPQSVVYQDEEGRWVTDLAYYTPFDKEQDFNVSLSNELSEDFRSGSDALDLIAQDEEEFNKEHQFMQEENIDAQNMSVALGDTSWGTSVNCGLLRRSLSASDVDRDDASYLRLSLGEFFAQRSEALGCLGGGYNVKRPSFGYFIRSPEKREPIALIRKSDLSRSNLGKEVADLNHGLFSGDLKAQLSEGSVTLQAEELESISQVDENDVTLTANKGKAEDTFLVSSKPQRHTDELPSESDSVLRISTIASAIAEASVSADPLQLATMIKALSNKTREKTCQEDGKQRHYSAVSHFLPNDLEKSNGSSTFDMERYLKKTDISQYEGGLDNFSRAGVSGIWDLSLSKERTTHNIHVVDLGATSISVREPEVGTAAGFYGESGDSVDQASLRTISSSNSVLTNVGEREGTAVDVKTHSIDHKSPDSGDGEKAASVPIPASDSCSVIGNPRVASLWLSEECKGLQESRDYQRQNECIGETSNSEKHVAFENHSIISPKRVDLKSPSPERGGQGSENGEDSFRPSTSPLSHSSPSEISGTSLSGCALESFGSAAQPQKGPCERELSQLTCPEASVSRLTYVSEQESISPSMASRRVLDDRKSDITSELSTTIIRASPVPAQEPAADKLGEKSPFQSRGKGALSYIIQKNLDTEKVTETTSLSSRPEDVKLDFSSSRLPSSKSEDRSQTSATGLTSDRGDLEQVSLALRSESSLHPATLAIPCLPVSRQAPVLDGGHVTPRDTSATDSEFSGQGPYRTSVPSVPSTEGCGPAPMRQHMPLTGPAVSVHYPLPVAPSAQPHSGALPAASSATLPRCRACGATACGLSCGLPGSCHPAVVGEHVQHSVTAGLCLGQDIGSGLMASSSLCNLYSDTLSQNLLNAAKVLPVQSLHPDCGIEPWDSAVVSGLGRVSVPEELKFPHACCVGIASQTYLSVLNPADRWLQVSIGVLSVSVDGEKVDFSAYPCLVFKNRVIIRPHATEEIKVLFIPSDPGIFRCIFSVASWPFSADAETVAQAEALASRVVLTAIAETPMIEVETEKKGVLDFGDLTYGSWKALPLKLVNKTHANIPIRLIISANAVAWRCFTFSKEPIHAALRALPYAHAIAQLAAPSVINHMMPASDDGQDPEFLVIWVLFHSPKKQITSSEILDSAEEFLARVDIEVDSPNPTPVIKSISLRARTGIARIHAPKDLQTLHLFASVASSARQYLPLKNAGNIDVHLDIKIPDQGSHFSVDPEKLFLKPGEEHEVIVSFSPKDPMGCEERILKIFVQPFGPQYEVMLKGEIVSSGNRPLAPESLTSDIPSILSNKQFLAWGGVPLGRTQLQKLALRNNSASTAQHLRLLVRGQDQDCFQLQHTFGSEERLTSNCEVRIRPKEDIYISVLFAPTRLSCMLAKLEIKQLGVRSQPGVKFTIPLSGYGGTSNLILEDVKKLSDSYMVTVNDLVPGQESRIVISVRNTGSRAAFVKAVGFKDSQKKVLLDPKVLRIFPDKFVLKERTQEDVTIIYNPSDRESSCKTTTELSTIYFFGGDEISRQQYRRAVLHMPEVRERVLPSLSVLHSIDFAEAFQDELLVTEVYDLPQQPNDVQLFYGNMRKIILSVIGEFRDSISSREFLPPSAKPSLEFKSESGSCGAHGGNISLDVLPVKGPQGSPLLSQAVPPPQDNSASEEVWAVHPEHLVLVAPSCDMAKTGRFQILNNSIRLLKFELYWPAHCLTVTPQHGFIAPESKMQILVSPNSSLSTKHSMFPWSGLIYIHCDNGQKKIVKVQIREDLTQEELFTHLTSGPLGILSQETEHVVNLVKPAAKPPSTKVELRNKTVTFPPTEPGETSGNYLELENHGDTEVRWHLSSLAPPYVKGVDESGDVFRATYAAFRCSPISGVVEGHSVQKVSIMFLPRDRGDYAQFWDVECHPLKEPHLKHTLRFQLSGHSVRAESEPGISRISANSLIKIDNLLKLRRQAVSEASALIPGRQLDLTHRGVYAPEDVYQFLPTRVGESRTLKVNLRNNSFITHSLKFLSPREPFYVKHSKYSLRFHM", "length": 2450, "header": "tr|A0AAA9T737-1|A0A3Q1LJH6_BOVIN Computationally mapped isoform of Centrosomal protein 192 OS=Bos taurus OX=9913 GN=CEP192 PE=4 SV=1 CANONICAL=A0A3Q1LJH6-1" }, "locus": { "chromosome": "24", "start_pos": 43287558, "end_pos": 43219979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104223.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104223.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093718.1" } ] } }, { "isoform_ac": "A0AAA9TE37-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE37/entry", "sequence": { "sequence": "MTVFSLAVSILRSLDWSFSCSKINFFSGLQFLGQTLSEMEDFRGIAEESFPSFLTSSLLGNSGILENVTLSSNLGLPVAVSTLARNRSSSENRYSDVQTSYLVEGKFSVPSETSPSSQSEDEPRERLRLVFSDDDSLAKKKNQTENQCLSDAVLRESAFPSDGARAEEEQARAAEPFLNQGPSNRASPLGQEQDSPIDFCSQSWMNKENKIGVPDVGKHFEKRNPNSDLSLTSFLENEKLISLASLEDSSDDDIDDEEFYDDHLEAYFEQLAIPGMMYEDLEGQEPPENYFKLPTSDPSQESGRAEVLVKSLRTPNTKLNPIDFNDTNASKDDFDLMDSLKLEEVSPHQNKHLTSDSETVLPVDRFLDTEMPQVSIQTNVDVASLKPVSDNAFNSTDAPWSPTSERQTCECYELVGKTKDQADPPQSVVYQDEEGRWVTDLAYYTPFDKEQDFNVSLSNELSEDFRSGSDALDLIAQDEEEFNKEHQFMQEENIDAQNMSVALGDTSWGTSVNCGLLRRSLSASDVDRDDASYLRLSLGEFFAQRSEALGCLGGGYNVKRPSFGYFIRSPEKREPIALIRKSDLSRSNLGKEVADLNHGLFSGDLKAQLSEGSVTLQAEELESISQVDENDVTLTANKGKAEDTFLVSSKPQRHTDELPSESDSVLRISTIASAIAEASVSADPLQLATMIKALSNKTREKTCQEDGKQRHYSAVSHFLPNDLEKSNGSSTFDMERYLKKTDISQYEGGLDNFSRAGVSGIWDLSLSKERTTHNIHVVDLGATSISVREPEVGTAAGFYGESGDSVDQASLRTISSSNSVLTNVGEREGTAVDVKTHSIDHKSPDSGDGEKAASVPIPASDSCSVIGNPRVASLWLSEECKGLQESRDYQRQNECIGETSNSEKHVAFENHSIISPKRVDLKSPSPERGGQGSENGEDSFRPSTSPLSHSSPSEISGTSLSGCALESFGSAAQPQKGPCERELSQLTCPEASVSRLTYVSEQESISPSMASRRVLDDRKSDITSELSTTIIRASPVPAQEPAADKLGEKSPFQSRGKGALSYIIQKNLDTEKVTETTSLSSRPEDVKLDFSSSRLPSSKSEDRSQTSATGLTSDRGDLEQVSLALRSESSLHPATLAIPCLPVSRQAPVLDGGHVTPRDTSATDSEFSGQGPYRTSVPSVPSTEGCGPAPMRQHMPLTGPAVSVHYPLPVAPSAQPHSGALPAASSATLPRCRACGATACGLSCGLPGSCHPAVVGEHVQHSVTAGLCLGQDIGSGLMASSSLCNLYSDTLSQNLLNAAKVLPVQSLHPDCGIEPWDSAVVSGLGRVSVPEELKFPHACCVGIASQTYLSVLNPADRWLQVSIGVLSVSVDGEKVDFSAYPCLVFKNRVIIRPHATEEIKVLFIPSDPGIFRCIFSVASWPFSADAETVAQAEALASRVVLTAIAETPMIEVETEKKGVLDFGDLTYGSWKALPLKLVNKTHANIPIRLIISANAVAWRCFTFSKEPIHAALRALPYAHAIAQLAAPSVINHMMPASDDGQDPEFLVIWVLFHSPKKQITSSEILDSAEEFLARVDIEVDSPNPTPVIKSISLRARTGIARIHAPKDLQTLHLFASVASSARQYLPLKNAGNIDVHLDIKIPDQGSHFSVDPEKLFLKPGEEHEVIVSFSPKDPMGCEERLQKLALRNNSASTAQHLRLLVRGQDQDCFQLQHTFGSEERLTSNCEVRIRPKEDIYISVLFAPTRLSCMLAKLEIKQLGVRSQPGVKFTIPLSGYGGTSNLILEDVKKLSDSYMVTVNDLVPGQESRIVISVRNTGSRAAFVKAVGFKDSQKKVLLDPKVLRIFPDKFVLKERTQEDVTIIYNPSDRESSCKTTTELSTIYFFGGDEISRQQYRRAVLHMPEVRERVLPSLSVLHSIDFAEAFQDELLVTEVYDLPQQPNDVQLFYGNMRKIILSVIGEFRDSISSREFLPPSAKPSLEFKSESGSCGAHGGNISLDVLPVKGPQGSPLLSQAVPPPQDNSASEEVWAVHPEHLVLVAPSCDMAKTGRFQILNNSIRLLKFELYWPAHCLTVTPQHGFIAPESKMQILVSPNSSLSTKHSMFPWSGLIYIHCDNGQKKIVKVQIREDLTQEELFTHLTSGPLGILSQETEHVVNLVKPAAKPPSTKVELRNKTVTFPPTEPGETSGNYLELENHGDTEVRWHLSSLAPPYVKGVDESGDVFRATYAAFRCSPISGVVEGHSVQKVSIMFLPRDRGDYAQFWDVECHPLKEPHLKHTLRFQLSGHSVRAESEPGISRISANSLIKIDNLLKLRRQAVSEASALIPGRQLDLTHRGVYAPEDVYQFLPTRVGESRTLKVNLRNNSFITHSLKFLSPREPFYVKHSKYSLRAQHYINMPVQFKPKSVGKFEDLLVVQTDEGKSVAVRLTGEALGNIS", "length": 2434, "header": "tr|A0AAA9TE37-1|A0A3Q1LJH6_BOVIN Computationally mapped isoform of Centrosomal protein 192 OS=Bos taurus OX=9913 GN=CEP192 PE=4 SV=1 CANONICAL=A0A3Q1LJH6-1" }, "locus": { "chromosome": "24", "start_pos": 43293240, "end_pos": 43219979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091514.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091514.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096414.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096414.1" } ] } }, { "isoform_ac": "A0AAA9TSQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ1/entry", "sequence": { "sequence": "MTVFSLAVSILRSLDWSFSCSKINFFSGLQFLGQTLSEMEDFRGIAEESFPSFLTSSLLGNSGILENVTLSSNLGLPVAVSTLARNRSSSENRYSDVQTSYLVEGKFSVPSETSPSSQSEDEPRERLRLVFSDDDSLAKKKNQTENQCLSDAVLRESAFPSDGARAEEEQARAAEPFLNQGPSNRASPLGQEQDSPIDFCSQSWMNKENKIGVPDVGKHFEKRNPNSDLSLTSFLENEKLISLASLEDSSDDDIDDEEFYDDHLEAYFEQLAIPGMMYEDLEGQEPPENYFKLPTSDPSQESGRAEVLVKSLRTPNTKLNPIDFNDTNASKDDFDLMDSLKLEEVSPHQNKHLTSDSETVLPVDRFLDTEMPQVSIQTNVDVASLKPVSDNAFNSTDAPWSPTSERQTCECYELVGKTKDQADPPQSVVYQDEEGRWVTDLAYYTPFDKEQDFNVSLSNELSEDFRSGSDALDLIAQDEEEFNKEHQFMQEENIDAQNMSVALGDTSWGTSVNCGLLRRSLSASDVDRDDASYLRLSLGEFFAQRSEALGCLGGGYNVKRPSFGYFIRSPEKREPIALIRKSDLSRSNLGKEVADLNHGLFSGDLKAQLSEGSVTLQAEELESISQVDENDVTLTANKGKAEDTFLVSSKPQRHTDELPSESDSVLRISTIASAIAEASVSADPLQLATMIKALSNKTREKTCQEDGKQRHYSAVSHFLPNDLEKSNGSSTFDMERYLKKTDISQYEGGLDNFSRAGVSGIWDLSLSKERTTHNIHVVDLGATSISVREPEVGTAAGFYGESGDSVDQASLRTISSSNSVLTNVGEREGTAVDVKTHSIDHKSPDSGDGEKAASVPIPASDSCSVIGNPRVASLWLSEECKGLQESRDYQRQNECIGETSNSEKHVAFENHSIISPKRVDLKSPSPERGGQGSENGEDSFRPSTSPLSHSSPSEISGTSLSGCALESFGSAAQPQKGPCERELSQLTCPEASVSRLTYVSEQESISPSMASRRVLDDRKSDITSELSTTIIRASPVPAQEPAADKLGEKSPFQSRGKGALSYIIQKNLDTEKVTETTSLSSRPEDVKLDFSSSRLPSSKSEDRSQTSATGLTSDRGDLEQVSLALRSESSLHPATLAIPCLPVSRQAPVLDGGHVTPRDTSATDSEFSGQGPYRTSVPSVPSTEGCGPAPMRQHMPLTGPAVSVHYPLPVAPSAQPHSGALPAASSATLPRCRACGATACGLSCGLPGSCHPAVVGEHVQHSVTAGLCLGQDIGSGLMASSSLCNLYSDTLSQNLLNAAKVLPVQSLHPDCGIEPWDSAVVSGLGRVSVPEELKFPHACCVGIASQTYLSVLNPADRWLQVSIGVLSVSVDGEKVDFSAYPCLVFKNRVIIRPHATEEIKVLFIPSDPGIFRCIFSVASWPFSADAETVAQAEALASRVVLTAIAETPMIEVETEKKGVLDFGDLTYGSWKALPLKLVNKTHANIPIRLIISANAVAWRCFTFSKEPIHAALRALPYAHAIAQLAAPSVINHMMPASDDGQDPEFLVIWVLFHSPKKQITSSEILDSAEEFLARVDIEVDSPNPTPVIKSISLRARTGIARIHAPKDLQTLHLFASVASSARQYLPLKNAGNIDVHLDIKIPDQGSHFSVDPEKLFLKPGEEHEVIVSFSPKDPMGCEERILKIFVQPFGPQYEVMLKGEIVSSGNRPLAPESLTSDIPSILSNKQFLAWGGVPLGRTQLQKLALRNNSASTAQHLRLLVRGQDQDCFQLQHTFGSEERLTSNCEVRIRPKEDIYISVLFAPTRLSCMLAKLEIKQLGVRSQPGVKFTIPLSGYGGTSNLILEDVKKLSDSYMVTVNDLVPGQESRIVISVRNTGSRAAFVKAVGFKDSQKKVLLDPKVLRIFPDKFVLKERTQEDVTIIYNPSDRESSCKTTTELSTIYFFGGDEISRQQYRRAVLHMPEVRERVLPSLSVLHSIDFAEAFQDELLVTEVYDLPQQPNDVQLFYGNMRKIILSVIGEFRDSISSREFLPPSAKPSLEFKSESGSCGAHGGNISLDVLPVKGPQGSPLLSQAVPPPQDNSASEEVWAVHPEHLVLVAPSCDMAKTGRFQILNNSIRLLKFELYWPAHCLTVTPQHGFIAPESKMQILVSPNSSLSTKHSMFPWSGLIYIHCDNGQKKIVKVQIREDLTQEELFTHLTSGPLGILSQETEHVVNLVKPAAKPPSTKVELRNKTVTFPPTEPGETSGNYLELENHGDTEVRWHLSSLAPPYVKGVDESGDVFRATYAAFRCSPISGVVEGHSVQKVSIMFLPRDRGDYAQFWDVECHPLKEPHLKHTLRFQLSGHSVRAESEPGISRISANSLIKIDNLLKLRRQAVSEASALIPGRQLDLTHRGVYAPEDVYQFLPTRVGESRTLKVNLRNNSFITHSSPALHQHARAVQAQVRGQV", "length": 2446, "header": "tr|A0AAA9TSQ1-1|A0A3Q1LJH6_BOVIN Computationally mapped isoform of Centrosomal protein 192 OS=Bos taurus OX=9913 GN=CEP192 PE=4 SV=2 CANONICAL=A0A3Q1LJH6-1" }, "locus": { "chromosome": "24", "start_pos": 43293158, "end_pos": 43219979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099671.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099671.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100083.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100083.2" } ] } }, { "isoform_ac": "F1MAX3-1", "url": "https://www.uniprot.org/uniprotkb/F1MAX3/entry", "sequence": { "sequence": "MTVFSLAVSILRSLDWSFSCSKINFFSGLQFLGQTLRYSDVQTSYLVEGKFSVPSETSPSSQSEDEPRERLRLVFSDDDSLAKKKNQTENQCLSDAVLRESAFPSDGARAEEEQARAAEPFLNQGPSNRASPLGQEQDSPIDFCSQSWMNKENKIGVPDVGKHFEKRNPNSDLSLTSFLENEKLISLASLEDSSDDDIDDEEFYDDHLEAYFEQLAIPGMMYEDLEGQEPPENYFKLPTSDPSQESGRAEVLVKSLRTPNTKLNPIDFNDTNASKDDFDLMDSLKLEEVSPHQNKHLTSDSETVLPVDRFLDTEMPQVSIQTNVDVASLKPVSDNAFNSTDAPWSPTSERQTCECYELVGKTKDQADPPQSVVYQDEEGRWVTDLAYYTPFDKEQDFNVSLSNELSEDFRSGSDALDLIAQDEEEFNKEHQFMQEENIDAQNMSVALGDTSWGTSVNCGLLRRSLSASDVDRDDASYLRLSLGEFFAQRSEALGCLGGGYNVKRPSFGYFIRSPEKREPIALIRKSDLSRSNLGKEVADLNHGLFSGDLKAQLSEGSVTLQAEELESISQVDENDVTLTANKGKAEDTFLVSSKPQRHTDELPSESDSVLRISTIASAIAEASVSADPLQLATMIKALSNKTREKTCQEDGKQRHYSAVSHFLPNDLEKSNGSSTFDMERYLKKTDISQYEGGLDNFSRAGVSGIWDLSLSKERTTHNIHVVDLGATSISVREPEVGTAAGFYGESGDSVDQASLRTISSSNSVLTNVGEREGTAVDVKTHSIDHKSPDSGDGEKAASVPIPASDSCSVIGNPRVASLWLSEECKGLQESRDYQRQNECIGETSNSEKHVAFENHSIISPKRVDLKSPSPERGGQGSENGEDSFRPSTSPLSHSSPSEISGTSLSGCALESFGSAAQPQKGPCERELSQLTCPEASVSRLTYVSEQESISPSMASRRVLDDRKSDITSELSTTIIRASPVPAQEPAADKLGEKSPFQSRGKGALSYIIQKNLDTEKVTETTSLSSRPEDVKLDFSSSRLPSSKSEDRSQTSATGLTSDRGDLEQVSLALRSESSLHPATLAIPCLPVSRQAPVLDGGHVTPRDTSATDSEFSGQGPYRTSVPSVPSTEGCGPAPMRQHMPLTGPAVSVHYPLPVAPSAQPHSGALPAASSATLPRCRACGATACGLSCGLPGSCHPAVVGEHVQHSVTAGLCLGQDIGSGLMASSSLCNLYSDTLSQNLLNAAKVLPVQSLHPDCGIEPWDSAVVSGLGRVSVPEELKFPHACCVGIASQTYLSVLNPADRWLQVSIGVLSVSVDGEKVDFSAYPCLVFKNRVIIRPHATEEIKVLFIPSDPGIFRCIFSVASWPFSADAETVAQAEALASRVVLTAIAETPMIEVETEKKGVLDFGDLTYGSWKALPLKLVNKTHANIPIRLIISANAVAWRCFTFSKEPIHAALRALPYAHAIAQLAAPSVINHMMPASDDGQDPEFLVIWVLFHSPKKQITSSEILDSAEEFLARVDIEVDSPNPTPVIKSISLRARTGIARIHAPKDLQTLHLFASVASSARQYLPLKNAGNIDVHLDIKIPDQGSHFSVDPEKLFLKPGEEHEVIVSFSPKDPMGCEERILKIFVQPFGPQYEVMLKGEIVSSGNRPLAPESLTSDIPSILSNKQFLAWGGVPLGRTQLQKLALRNNSASTAQHLRLLVRGQDQDCFQLQHTFGSEERLTSNCEVRIRPKEDIYISVLFAPTRLSCMLAKLEIKQLGVRSQPGVKFTIPLSGYGGTSNLILEDVKKLSDSYMVTVNDLVPGQESRIVISVRNTGSRAAFVKAVGFKDSQKKVLLDPKVLRIFPDKFVLKERTQEDVTIIYNPSDRESSCKTTTELSTIYFFGGDEISRQQYRRAVLHMPEVRERVLPSLSVLHSIDFAEAFQDELLVTEVYDLPQQPNDVQLFYGNMRKIILSVIGEFRDSISSREFLPPSAKPSLEFKSESGSCGAHGGNISLDVLPVKGPQGSPLLSQAVPPPQDNSASEEVWAVHPEHLVLVAPSCDMAKTGRFQILNNSIRLLKFELYWPAHCLTVTPQHGFIAPESKMQILVSPNSSLSTKHSMFPWSGLIYIHCDNGQKKIVKVQIREDLTQEELFTHLTSGPLGILSQETEHVVNLVKPAAKPPSTKVELRNKTVTFPPTEPGETSGNYLELENHGDTEVRWHLSSLAPPYVKGVDESGDVFRATYAAFRCSPISGVVEGHSVQKVSIMFLPRDRGDYAQFWDVECHPLKEPHLKHTLRFQLSGHSVRAESEPGISRISANSLIKIDNLLKLRRQAVSEASALIPGRQLDLTHRGVYAPEDVYQFLPTRVGESRTLKVNLRNNSFITHSLKFLSPREPFYVKHSKYSLRAQHYINMPVQFKPKSVGKFEDLLVVQTDEGKSVAVRLTGEALGNIS", "length": 2437, "header": "tr|F1MAX3-1|A0A3Q1LJH6_BOVIN Computationally mapped isoform of Centrosomal protein 192 OS=Bos taurus OX=9913 GN=CEP192 PE=4 SV=3 CANONICAL=A0A3Q1LJH6-1" }, "locus": { "chromosome": "24", "start_pos": 43293240, "end_pos": 43219979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017803.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017803.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017803.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017803.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1156, "start_aa": "Thr", "end_pos": 1156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1156", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1585, "start_aa": "Thr", "end_pos": 1585, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1585", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "centrosome-templated microtubule nucleation", "id": "GO:0090222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090222", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "centrosome duplication", "id": "GO:0051298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051298", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" }, { "name": "procentriole", "id": "GO:0120098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120098", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1479, "end_pos": 1481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1747, "end_pos": 1749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2052, "end_pos": 2054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2112, "end_pos": 2114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2151, "end_pos": 2153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2230, "end_pos": 2232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2420, "end_pos": 2422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2491, "end_pos": 2493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": 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"expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EVX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1", "locus": { "chromosome": "2", "start_pos": 20832971, "end_pos": 20829348, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000049537", "url": "https://www.ensembl.org/id/ENSBTAG00000049537" } ] } } ], "crossref": [ { "id": "A0A3Q1LJP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LJP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049537", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049537", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112442311", "url": "https://www.ncbi.nlm.nih.gov/gene/112442311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:112442311", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112442311", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKGYAES", "url": "https://omabrowser.org/oma/group/NKGYAES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LJP1", "url": "https://www.orthodb.org/?gene=A0A3Q1LJP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46294:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46294:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024834839", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834839", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMERIRKEMILMERGLHSPTTGKRFSNLSDSAGNAVLEALENSQHPARLSPRLPSAPLHSALGDLPAKGKFEIDTLFNLQHPSSESTVSSEIASAAEGRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAVPLKENNGKGFAESGSVAGTTTSATGSGLGSLHGGGGGGGSGGGTALGGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQTPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGSGGGGGSTGAAGGSDFGCSGAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR", "length": 474, "header": "tr|A0A3Q1LJP1-1|A0A3Q1LJP1_BOVIN Isoform 1 of Homeobox even-skipped homolog protein 2 OS=Bos taurus OX=9913 GN=EVX2 PE=3 SV=1 CANONICAL=A0A3Q1LJP1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1/entry", "sequence": { "sequence": "MMERIRKEMILMERGLHSPTTGKRFSNLSDSAGNAVLEALENSQHPARLSPRLPSAPLHSALGDLPAKGKFEIDTLFNLQHPSSESTVSSEIASAAEGRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAVPLKENNGKGFAESGSVAGTTTSATGSGLGSLHGGGGGGGSGGGTALGGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQTPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGSGGGGGSTGAAGGSDFGCSGAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR", "length": 474, "header": "tr|A0A3Q1LJP1-1|A0A3Q1LJP1_BOVIN Isoform 1 of Homeobox even-skipped homolog protein 2 OS=Bos taurus OX=9913 GN=EVX2 PE=3 SV=1 CANONICAL=A0A3Q1LJP1-1" }, "locus": { "chromosome": "2", "start_pos": 20832968, "end_pos": 20829348, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073770.1", "url": "https://www.ensembl.org/id/ENSBTAT00000073770.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056678.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056678.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:112442311", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112442311", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A6N9-1", "protein_name": "Homeobox even-skipped homolog protein 2", "gene_name": "EVX2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMERIRKEMILMERGLHSPTAGKRLSNLSDSAGNAVLEALENSQHTGRLSPRLTSSSLHGAIGDISAKGKFEIDALFNLQHPSGESTVSSEIPPSESRKKISLYPEVAQEAEMNSDVEVGCSALRSPASLPSSQLKENGTKGFAESSPAPSTPAAPGLGLHGGSALSGSAAGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAGLNSGAAASAAAAAAAAAAAAAGSGPPGGSAPCSCLSCHSSQTAAAAAAASALGSRGSAADFPCTAGAQRSESGFLPYSAAVLGKAAVASPEQREEAPLTR", "length": 436 }, "evidence": [ { "id": "A0A3Q1LJP1", "url": "https://omabrowser.org/oma/group/A0A3Q1LJP1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACC8-1", "protein_name": "Homeobox even-skipped homolog protein 2", "gene_name": "Evx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMERIRKEMILMERGLHSPTAGKRFSNLSDSSGSAVLEALENSQHPARLSPRLPSAPLHGALGDLPAKGKFEIDTLFNLQHPSSESTVSSEIASATESRKKPSHYSEAAAEADMSSDVEVGCSALRSPSGLGAAQLKENNAKGYAESGSVAGTTTSATGSGLGSLHGGGGGNSGGAALGGSGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPATAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGSGGGGGGGAGTAGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR", "length": 474 }, "evidence": [ { "id": "A0A3Q1LJP1", "url": "https://omabrowser.org/oma/group/A0A3Q1LJP1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LGI0-1", "protein_name": "Homeobox even-skipped homolog protein 2", "gene_name": "EVX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMERIRKEMILMERGLHSPTAGKRFSNLSDSAGNAVLEALENSQHPARLSPRLPSAPLHSALGDLPAKGKFEIDTLFNLQHPGSESTVSSEIASAAEGRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAAPLKENNGKGYAESGSAAGTTTSASGSGLGSLHGGGGSGGSGGGPALGGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQTPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGAGAAGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR", "length": 474 }, "evidence": [ { "id": "A0A3Q1LJP1", "url": "https://omabrowser.org/oma/group/A0A3Q1LJP1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P49749-1", "protein_name": "Homeobox even-skipped homolog protein 2", "gene_name": "Evx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMERIRKEMILMERGLHSPTAGKRFSSLSDSAGGAVLEALENSQHPARLSPRLPSAPLHGALGDLPAKGKFEIDTLFNLQHPSSESTVSSEIASATESRKKPSHYSEAAAEADMSSDVEVGCSALRSPSGLGAAPLKENNAKGYTESGSVAGTTTSASGSGLGSLHGGGGGGNSGAAALGGSGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGSSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGSGGGGGGGAGTAGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR", "length": 475 }, "evidence": [ { "id": "A0A3Q1LJP1", "url": "https://omabrowser.org/oma/group/A0A3Q1LJP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q03828-1", "protein_name": "Homeobox even-skipped homolog protein 2", "gene_name": "EVX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMERIRKEMILMERGLHSPTAGKRFSNLSNSAGNAVLEALENSQHPARLSPRLPSAPLHSALGELPAKGKFEIDTLFNLQHTGSESTVSSEISSAAESRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAAQLKENNGKGYAESGSAAGTTTSASGSGLGSLHGGSGGSGGSAALGGSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPPDQRDEAPLTR", "length": 476 }, "evidence": [ { "id": "A0A3Q1LJP1", "url": "https://omabrowser.org/oma/group/A0A3Q1LJP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LJP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 474, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LJP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LJP1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LJP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJP1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 248, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": 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"table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LJR3-1", "uniprot_ac": "A0A3Q1LJR3", "uniprot_id": "A0A3Q1LJR3_BOVIN", "mass": { "chemical_mass": 71256.0, "monoisotopic_mass": 71256.0 }, "refseq": {}, "gene_names": [ { "name": "GPAA1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3" } ] } ], "protein_names": [ { "name": "GPI-anchor transamidase component GPAA1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3/entry#names_and_taxonomy" } ] }, { "name": "GAA1 protein homolog", "type": "synonym", "evidence": [ { "id": "A0A3Q1LJR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3/entry#names_and_taxonomy" } ] }, { "name": "Glycosylphosphatidylinositol anchor attachment 1 protein", "type": "synonym", "evidence": [ { "id": "A0A3Q1LJR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. Binds GPI-anchor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3#function" }, { "database": "UniProtKB", "id": "ARBA00093336", "url": "https://www.uniprot.org/uniprotkb/ARBA00093336#function" }, { "database": "UniProtKB", "id": "A0AAA9SPM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPM1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPAA1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3", "locus": { "chromosome": "14", "start_pos": 750591, "end_pos": 754031, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014610", "url": "https://www.ensembl.org/id/ENSBTAG00000014610" } ] } } ], "crossref": [ { "id": "A0A3Q1LJR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LJR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014610", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014610", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LJR3", "url": "https://www.orthodb.org/?gene=A0A3Q1LJR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13304:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13304:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LJR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVA3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTMVEEQFAGGDRARSLARDFAAHRRKSGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGINVYGILRAPRAASTESLVLTVPCGPDSTNSQAVGLMLALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDVNITGMQSSPLQGRAGAIQAAVALELSSDVVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSIDGPLQSVQTLLLMVLQQASGRPHGAHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPAAGFLLLVLGLKALELWMQLHEAGVGPEEAGENPPHPLTQGVGLASLVAPLLVSQAMGLALYILPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLACITLTNFSLGFLLAASMVPAAAITKPSEPRYVLLSPHCRARTPPHGFYLTRSSSPPGASAPPQGALCCPAGADEPSSYTPGQPVPVAGAAGGTALPDRGLAALPGHAGPGRAGAPHLRRPALPTAGSGPLPLLAALLERALLEVTEAAGSSPRSLLPRK", "length": 666, "header": "tr|A0A3Q1LJR3-1|A0A3Q1LJR3_BOVIN Isoform 1 of GPI-anchor transamidase component GPAA1 OS=Bos taurus OX=9913 GN=GPAA1 PE=4 SV=2 CANONICAL=A0A3Q1LJR3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3/entry", "sequence": { "sequence": "MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTMVEEQFAGGDRARSLARDFAAHRRKSGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGINVYGILRAPRAASTESLVLTVPCGPDSTNSQAVGLMLALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDVNITGMQSSPLQGRAGAIQAAVALELSSDVVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSIDGPLQSVQTLLLMVLQQASGRPHGAHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPAAGFLLLVLGLKALELWMQLHEAGVGPEEAGENPPHPLTQGVGLASLVAPLLVSQAMGLALYILPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLACITLTNFSLGFLLAASMVPAAAITKPSEPRYVLLSPHCRARTPPHGFYLTRSSSPPGASAPPQGALCCPAGADEPSSYTPGQPVPVAGAAGGTALPDRGLAALPGHAGPGRAGAPHLRRPALPTAGSGPLPLLAALLERALLEVTEAAGSSPRSLLPRK", "length": 666, "header": "tr|A0A3Q1LJR3-1|A0A3Q1LJR3_BOVIN Isoform 1 of GPI-anchor transamidase component GPAA1 OS=Bos taurus OX=9913 GN=GPAA1 PE=4 SV=2 CANONICAL=A0A3Q1LJR3-1" }, "locus": { "chromosome": "14", "start_pos": 753834, "end_pos": 750631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080296.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080296.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059710.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059710.2" } ] } }, { "isoform_ac": "A0AAA9SPM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPM1/entry", "sequence": { "sequence": "MGLLSDPVRRRALARLVLRLNAPLWALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYMVSGINVYGILRAPRAASTESLVLTVPCGPDSTNSQAVGLMLALAAHFRGQIYWAKDIIFLVTEHDLLGTEAWLEAYHDVNITGMQSSPLQGRAGAIQAAVALELSSDVVTSLDVAVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSIDGPLQSVQTLLLMVLQQASGRPHGAHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPAAGFLLLVLGLKALELWMQLHEAGVGPEEAGENPPHPLTQGVGLASLVAPLLVSQAMGLALYILPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLACITLTNFSLGFLLAASMVPAAAITKPSEPRALYAALLVLTSPAATLLGSLFLWRELQEAPLSLTEGWQLFLATLAQGVLEHHTYGALLFPLLALGLYPCWLLFWNVLFWK", "length": 557, "header": "tr|A0AAA9SPM1-1|A0A3Q1LJR3_BOVIN Computationally mapped isoform of GPI-anchor transamidase component GPAA1 OS=Bos taurus OX=9913 GN=GPAA1 PE=4 SV=1 CANONICAL=A0A3Q1LJR3-1" }, "locus": { "chromosome": "14", "start_pos": 753834, "end_pos": 750678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112865.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112865.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085947.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085947.1" } ] } }, { "isoform_ac": "A0AAA9TVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA3/entry", "sequence": { "sequence": "MGLLSDPVRRRALARLVLRLNAPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTMVEEQFAGGDRARSLARDFAAHRRKSGALPVAWLERTMRSVGLEVYTQSFSRKLPFPDETHERYTFCQKGGLLCTLQGKLQPQDWTSIDGPLQSVQTLLLMVLQQASGRPHGAHGLFLRYRVEALTLRGINSFRQYKYDLVAVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPAAGFLLLVLGLKALELWMQLHEAGVGPEEAGENPPHPLTQGVGLASLVAPLLVSQAMGLALYILPVLGQHVATQHFPVAEAEAVVLTLLAIYAAGLALPHNTHRVVSTQAPDRGWMALKLVALIYLALQLACITLTNFSLGFLLAASMVPAAAITKPSEPRALYAALLVLTSPAATLLGSLFLWRELQEAPLSLTEGWQLFLATLAQGVLEHHTYGALLFPLLALGLYPCWLLFWNVLFWK", "length": 483, "header": "tr|A0AAA9TVA3-1|A0A3Q1LJR3_BOVIN Computationally mapped isoform of GPI-anchor transamidase component GPAA1 OS=Bos taurus OX=9913 GN=GPAA1 PE=4 SV=1 CANONICAL=A0A3Q1LJR3-1" }, "locus": { "chromosome": "14", "start_pos": 753834, "end_pos": 750678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109190.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109190.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102296.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102296.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 586, "start_aa": "Thr", "end_pos": 586, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr586", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GPI anchor binding", "id": "GO:0034235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034235", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3" } ], "pmid": "" }, { "name": "attachment of GPI anchor to protein", "id": "GO:0016255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016255", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "GPI-anchor transamidase complex", "id": "GO:0042765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042765", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJR3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LJR3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 666, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LJR3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LJR3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 586 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 513, "end_pos": 515 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LJS7-1", "uniprot_ac": "A0A3Q1LJS7", "uniprot_id": "A0A3Q1LJS7_BOVIN", "mass": { "chemical_mass": 35302.0, "monoisotopic_mass": 35302.0 }, "refseq": { "ac": "NP_001377556", "name": "olfactory receptor family 13 subfamily D member 2C", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377556" }, "gene_names": [ { "name": "OR13D2C", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJS7" } ] }, { "name": "OR13D2C", "type": "synonym", "evidence": [ { "id": "NP_001377556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377556" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJS7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 13D1", "type": "synonym", "evidence": [ { "id": "NP_001377556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377556" } ] }, { "name": "olfactory receptor family 13 subfamily D member 2C", "type": "synonym", "evidence": [ { "id": "NP_001377556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377556" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJS7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJS7#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377556" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJS7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJS7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJS7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJS7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR13D2C", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJS7", "locus": { "chromosome": "8", "start_pos": 94410123, "end_pos": 94409188, 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"categories": [] }, { "id": "ENSBTAG00000015764", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015764", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21948", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21948", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512380", "url": "https://www.ncbi.nlm.nih.gov/gene/512380", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": 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"PF03451", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03451", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LJU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJ25-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { 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"MEVDDRVSALEQRLQLQEDELAVLKAALADALRRLRACEEQGAALRARGTPKGRAPPRLGTTASVCQLLKGLPTRTPLNGSGPPRRVGGYATSPSSPKKEATSGRSARRYLSPERLASVRREDPRSRTTSSSSNCSAKKEGKTKEVIFSMAEEGSVKMFLRGRPVPMLIPEELVPTYSLDTRSELPSHRFKLDWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHVLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHVYFWNLEGGSLSKRQGLFEKYEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGRGDTLYVGTTRNSILQGSVHTGFSLLVQGHMEELWGLATHPSRAQFVTCGQDKLVHLWSVESHQPLWSRTIEDPARSAGFHPSGSVLAIGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDSSTCKQITTAETVRNVEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV", "length": 784, "header": "tr|A0A3Q1LJU5-1|A0A3Q1LJU5_BOVIN Isoform 1 of EMAP like 2 OS=Bos taurus OX=9913 GN=EML2 PE=3 SV=2 CANONICAL=A0A3Q1LJU5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5/entry", "sequence": { "sequence": "MEVDDRVSALEQRLQLQEDELAVLKAALADALRRLRACEEQGAALRARGTPKGRAPPRLGTTASVCQLLKGLPTRTPLNGSGPPRRVGGYATSPSSPKKEATSGRSARRYLSPERLASVRREDPRSRTTSSSSNCSAKKEGKTKEVIFSMAEEGSVKMFLRGRPVPMLIPEELVPTYSLDTRSELPSHRFKLDWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHVLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHVYFWNLEGGSLSKRQGLFEKYEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGRGDTLYVGTTRNSILQGSVHTGFSLLVQGHMEELWGLATHPSRAQFVTCGQDKLVHLWSVESHQPLWSRTIEDPARSAGFHPSGSVLAIGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDSSTCKQITTAETVRNVEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV", "length": 784, "header": "tr|A0A3Q1LJU5-1|A0A3Q1LJU5_BOVIN Isoform 1 of EMAP like 2 OS=Bos taurus OX=9913 GN=EML2 PE=3 SV=2 CANONICAL=A0A3Q1LJU5-1" }, "locus": { "chromosome": "18", "start_pos": 53229119, "end_pos": 53207453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083850.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083850.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059750.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059750.2" } ] } }, { "isoform_ac": "A0AAA9TJ25-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJ25/entry", "sequence": { "sequence": "MDREAWRAAAHGSQRVGNDCATELNCGHRWTWTDPSSKTKEVIFSMAEEGSVKMFLRGRPVPMLIPEELVPTYSLDTRSELPSHRFKLDWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHVLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHVYFWNLEGGSLSKRQGLFEKYEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGRGDTLYVGTTRNSILQGSVHTGFSLLVQGHMEELWGLATHPSRAQFVTCGQDKLVHLWSVESHQPLWSRTIEDPARSAGFHPSGSVLAIGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDSSTCKQITTAETVRNVEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV", "length": 680, "header": "tr|A0AAA9TJ25-1|A0A3Q1LJU5_BOVIN Computationally mapped isoform of EMAP like 2 OS=Bos taurus OX=9913 GN=EML2 PE=3 SV=2 CANONICAL=A0A3Q1LJU5-1" }, "locus": { "chromosome": "18", "start_pos": 53227716, "end_pos": 53207453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093905.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093905.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098449.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098449.2" } ] } }, { "isoform_ac": "E1BB08-1", "url": "https://www.uniprot.org/uniprotkb/E1BB08/entry", "sequence": { "sequence": "MSSFGPGKTKEVIFSMAEEGSVKMFLRGRPVPMLIPEELVPTYSLDTRSELPSHRFKLDWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHVLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHVYFWNLEGGSLSKRQGLFEKYEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGRGDTLYVGTTRNSILQGSVHTGFSLLVQGHMEELWGLATHPSRAQFVTCGQDKLVHLWSVESHQPLWSRTIEDPARSAGFHPSGSVLAIGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDSSTCKQITTAETVRNVEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV", "length": 650, "header": "tr|E1BB08-1|A0A3Q1LJU5_BOVIN Computationally mapped isoform of EMAP like 2 OS=Bos taurus OX=9913 GN=EML2 PE=3 SV=5 CANONICAL=A0A3Q1LJU5-1" }, "locus": { "chromosome": "18", "start_pos": 53226906, "end_pos": 53207453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020933.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020933.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020933.8", "url": "https://www.ensembl.org/id/ENSBTAP00000020933.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of microtubule nucleation", "id": "GO:0010968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010968", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" } ], "pmid": "" }, { "name": "negative regulation of microtubule polymerization", "id": "GO:0031115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031115", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LJU5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 784, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LJU5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LJU5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LJU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" }, { "id": "PF23409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like first beta-propeller", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 498, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LJU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU5" }, { "id": "PF23414", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like second beta-propeller", "eco_id": "ECO_0000259", "start_pos": 515, "end_pos": 783, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LJU9-1", "uniprot_ac": "A0A3Q1LJU9", "uniprot_id": "A0A3Q1LJU9_BOVIN", "mass": { "chemical_mass": 138549.0, "monoisotopic_mass": 138549.0 }, "refseq": { "ac": "XP_005227171", "name": "latent-transforming growth factor beta-binding protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227171" }, "gene_names": [ { "name": "LTBP3", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9" } ] }, { "name": "LTBP3", "type": "synonym", "evidence": [ { "id": "XP_005227171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227171" } ] } ], "protein_names": [ { "name": "Latent-transforming growth factor beta-binding protein 3", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9/entry#names_and_taxonomy" } ] }, { "name": "latent-transforming growth factor beta-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005227171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227171" } ] } ], "function": [ { "annotation": "Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9#function" }, { "database": "UniProtKB", "id": "ARBA00057882", "url": "https://www.uniprot.org/uniprotkb/ARBA00057882#function" }, { "database": "UniProtKB", "id": "E1BL59", "url": "https://www.uniprot.org/uniprotkb/E1BL59#function" }, { "database": "UniProtKB", "id": "A0A3Q1MCM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCM4#function" }, { "database": "UniProtKB", "id": "A0AAA9S0P5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0P5#function" }, { "database": "UniProtKB", "id": "A0AAA9T7X7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7X7#function" }, { "database": "UniProtKB", "id": "A0ABI0P409", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P409#function" }, { "database": "UniProtKB", "id": "A0AAA9SMP2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LTBP3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9", "locus": { "chromosome": "29", "start_pos": 43714477, "end_pos": 43735024, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006747", "url": "https://www.ensembl.org/id/ENSBTAG00000006747" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006747", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532772", "url": "https://www.ncbi.nlm.nih.gov/gene/532772", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL59", "url": "https://www.uniprot.org/uniprotkb/E1BL59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BL59-1", "url": "https://www.uniprot.org/uniprotkb/E1BL59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGAGGSGPGLGRAGALSTGALPPLAPEGESVASKHAMYAVQVIADPPGPGEGPPAQHATFLVPLGPGQISAEVQAPPPVVNVRVHHPAEASVQVHRIEGPNAEGPAPSQHLLPHPKPAHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEMGTDCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPAQDGRSCLDVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDINECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMDVDECQDPTACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQRPESPAERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 1297, "header": "tr|A0A3Q1LJU9-1|A0A3Q1LJU9_BOVIN Isoform 1 of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A3Q1LJU9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9/entry", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGAGGSGPGLGRAGALSTGALPPLAPEGESVASKHAMYAVQVIADPPGPGEGPPAQHATFLVPLGPGQISAEVQAPPPVVNVRVHHPAEASVQVHRIEGPNAEGPAPSQHLLPHPKPAHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEMGTDCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPAQDGRSCLDVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDINECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMDVDECQDPTACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQRPESPAERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 1297, "header": "tr|A0A3Q1LJU9-1|A0A3Q1LJU9_BOVIN Isoform 1 of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A3Q1LJU9-1" }, "locus": { "chromosome": "29", "start_pos": 43734825, "end_pos": 43715947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075583.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075583.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059761.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059761.1" } ] } }, { "isoform_ac": "A0A3Q1MCM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCM4/entry", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGAGGSGPGLGRAGALSTGALPPLAPEGESVASKHAMYAVQVIADPPGPGEGPPAQHATFLVPLGPGQISAEVQAPPPVVNVRVHHPAEASVQVHRIEGPNAEGPAPSQHLLPHPKPAHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEMGTDCPQGYKRLNSTHCQADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPAQDGRSCLDVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDINECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMDVDECQDPTACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQRPESPAERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 1256, "header": "tr|A0A3Q1MCM4-1|A0A3Q1LJU9_BOVIN Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A3Q1LJU9-1" }, "locus": { "chromosome": "29", "start_pos": 43734825, "end_pos": 43715947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081262.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081262.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066538.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066538.1" } ] } }, { "isoform_ac": "A0AAA9S0P5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0P5/entry", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGAGGSGPGLGRAGALSTGALPPLAPEGESVASKHAMYAVQVIADPPGPGEGPPAQHATFLVPLGPGQISAEVQAPPPVVNVRVHHPAEASVQVHRIEGPNAEGPAPSQHLLPHPKPAHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEMGTDCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDINECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMDVDECQDPTACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQRPESPAERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 1256, "header": "tr|A0AAA9S0P5-1|A0A3Q1LJU9_BOVIN Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A3Q1LJU9-1" }, "locus": { "chromosome": "29", "start_pos": 43734825, "end_pos": 43715947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105979.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105979.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077209.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077209.1" } ] } }, { "isoform_ac": "A0AAA9SMP2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMP2/entry", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGAGGSGPGLGRAGALSTGALPPLAPEGESVASKHAMYAVQVIADPPGPGEGPPAQHATFLVPLGPGQISAEVQAPPPVVNVRVHHPAEASVQVHRIEGPNAEGPAPSQHLLPHPKPAHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEMGTDCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPAQDGRSCLGDGLRDESQRNWRTMDTDCGAQGCRPQWSLGVSGKPQGDWEKRRHVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDINECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMDVDECQDPTACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQRPESPAERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 1341, "header": "tr|A0AAA9SMP2-1|A0A3Q1LJU9_BOVIN Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A3Q1LJU9-1" }, "locus": { "chromosome": "29", "start_pos": 43734825, "end_pos": 43715947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111966.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111966.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084035.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084035.1" } ] } }, { "isoform_ac": "A0AAA9T7X7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7X7/entry", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPAQDGRSCLDVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDINECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 965, "header": "tr|A0AAA9T7X7-1|A0A3Q1LJU9_BOVIN Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A3Q1LJU9-1" }, "locus": { "chromosome": "29", "start_pos": 43734825, "end_pos": 43715947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088675.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088675.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094839.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094839.1" } ] } }, { "isoform_ac": "A0ABI0P409-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P409/entry", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGAGGSGPGLGRAGALSTGALPPLAPEGESVASKHAMYAVQVIADPPGPGEGPPAQHATFLVPLGPGQISAEVQAPPPVVNVRVHHPAEASVQVHRIEGPNAEGPAPSQHLLPHPKPAHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEMGTDCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPAQDGRSCLDVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMDVDECQDPTACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQRPESPAERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 1257, "header": "tr|A0ABI0P409-1|A0ABI0P409_BOVIN Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=1 CANONICAL=A0A3Q1LJU9-1" }, "locus": { "chromosome": "29", "start_pos": 43734825, "end_pos": 43715947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136985.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136985.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105984.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105984.1" } ] } }, { "isoform_ac": "E1BL59-1", "url": "https://www.uniprot.org/uniprotkb/E1BL59/entry", "sequence": { "sequence": "MPGPRGAAGGLAPEMRGAGAAGLLALLLLLLLGPGGGAEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQKGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGGAGGSGPGLGRAGALSTGALPPLAPEGESVASKHAMYAVQVIADPPGPGEGPPAQHATFLVPLGPGQISAEVQAPPPVVNVRVHHPAEASVQVHRIEGPNAEGPAPSQHLLPHPKPAHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEMGTDCPQGYKRLNSTHCQDINECAMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPPPEDTEEERGVSTDSPVIEEQSAQQSHPTVTVSPARPYPELISWPPPPQFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGAGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSTCPDSKCENKPGSFKCIACLPGYRSQGGGACRDVNECAEGNPCSPGWCENLPGSFRCTCAQGYAPAQDGRSCLDVDECEAGDVCDNGICANTPGSFQCQCLSGYHLSRDRSRCEDINECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCICDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCQHGFYYDSNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPVQRQCLSPEEMERAPERRDVCWGQRGDDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSQCPTSQSESNSFWDTSPLLLGKPAREEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKTERCVNTSGSYRCVCKAGFARSRTHGACVPQRRR", "length": 1250, "header": "tr|E1BL59-1|E1BL59_BOVIN Computationally mapped isoform of Latent-transforming growth factor beta-binding protein 3 OS=Bos taurus OX=9913 GN=LTBP3 PE=3 SV=2 CANONICAL=A0A3Q1LJU9-1" }, "locus": { "chromosome": "29", "start_pos": 43734825, "end_pos": 43715947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008880.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008880.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008880.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008880.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532772", "resource": "KEGG Pathway" }, { "id": "R-BTA-2129379", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2129379", "resource": "Reactome", "description": "Molecules associated with elastic fibres" }, { "id": "R-BTA-2173789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2173789", "resource": "Reactome", "description": "TGF-beta receptor signaling activates SMADs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AVC5-1", "protein_name": "Latent-transforming growth factor beta-binding protein 3", "gene_name": "Ltbp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGPRGAARGLAPAMRQAGASGLLALLLLALLGPGGGAEGGPAGERGTGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAAGTGAGTGSSGPGLARTGAMSTGPLPPLVPEGESVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIEGPNAEGPASSQHLLPHPKPPHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECVMPGMCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSTEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPADGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSRAPALEDTEEERGVTLDPPVSEERSVQQSHPTTTTSPARPYPELISRPSPPTFHRFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGQCVPGPSDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKTSRPPVCEDIDECRDPSTCPDGKCENKPGSFKCIACQPGYRSQGGGACRDINECSEGSPCSPGWCENLPGSYRCTCAQGYEPALDGLSCIDMDECETGNICHDGICTNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQDPGLCLPHGACENLQGSYVCVCDEGFTLTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECILFGAEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMGEARGISAGSRAQEEMDMDECQDPAACRPGRCVNLPGSYRCECHPPWVPGSSGRDCQLPESQAEHGPERREVCWGQRGEDGMCMGPLAGPALTFDDCCCRQGRGWGTQCRPCPPRGTGSQCPTSQSESNSFWDTSPLLLGKSPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFTRSRPHGACVPQRRR", "length": 1316 }, "evidence": [ { "id": "A0A3Q1LJU9", "url": "https://omabrowser.org/oma/group/A0A3Q1LJU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61810-1", "protein_name": "Latent-transforming growth factor beta-binding protein 3", "gene_name": "Ltbp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9" } ], "pmid": "" }, { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377202" }, "gene_names": [ { "name": "OR4A2C", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJW5" } ] }, { "name": "OR4A16", "type": "synonym", "evidence": [ { "id": "NP_001377202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377202" } ] }, { "name": "OR4A2C", "type": "synonym", "evidence": [ { "id": "NP_001377202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377202" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJW5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily A member 2C", "type": "synonym", "evidence": [ { "id": "NP_001377202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377202" } ] }, { "name": "olfactory receptor, family 4, subfamily A, member 16", "type": "synonym", "evidence": [ { "id": "NP_001377202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377202" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377202", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377202" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJW5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LJW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJW5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4A2C", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJW5", "locus": { "chromosome": "15", "start_pos": 84427018, "end_pos": 84426101, 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LK26-1", "uniprot_ac": "A0A3Q1LK26", "uniprot_id": "A0A3Q1LK26_BOVIN", "mass": { "chemical_mass": 53856.0, "monoisotopic_mass": 53856.0 }, "refseq": { "ac": "XP_010802291", "name": "epsilon-sarcoglycan isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802291" }, "gene_names": [ { "name": "SGCE", "type": "recommended", "evidence": [ { "id": "A0A3Q1LK26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ] }, { "name": "SGCE", "type": "synonym", "evidence": [ { "id": "XP_010802291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802291" } ] } ], "protein_names": [ { "name": "Epsilon-sarcoglycan", "type": "recommended", "evidence": [ { "id": "A0A3Q1LK26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26/entry#names_and_taxonomy" } ] }, { "name": "epsilon-sarcoglycan isoform X3", "type": "synonym", "evidence": [ { "id": "XP_010802291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802291" } ] } ], "function": [ { "annotation": "Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S9D8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9D8#function" }, { "database": "UniProtKB", "id": "ARBA00002860", "url": "https://www.uniprot.org/uniprotkb/ARBA00002860#function" }, { "database": "UniProtKB", "id": "A0AAA9T6H0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6H0#function" }, { "database": "UniProtKB", "id": "A0AAA9TJA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA7#function" }, { "database": "UniProtKB", "id": "A0AAA9TML4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML4#function" }, { "database": "UniProtKB", "id": "A0AAA9TW73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW73#function" }, { "database": "UniProtKB", "id": "A0A3Q1M668", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M668#function" }, { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26#function" }, { "database": "UniProtKB", "id": "F1MYZ0", "url": "https://www.uniprot.org/uniprotkb/F1MYZ0#function" }, { "database": "UniProtKB", "id": "A0ABI0P493", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P493#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SGCE", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26", "locus": { "chromosome": "4", "start_pos": 11992415, "end_pos": 12177550, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021282", "url": "https://www.ensembl.org/id/ENSBTAG00000021282" } ] } } ], "crossref": [ { "id": "A0A3Q1LK26", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LK26", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021282", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021282", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "407209", "url": "https://www.ncbi.nlm.nih.gov/gene/407209", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10132:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10132:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010802291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802291", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M668", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M668", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M668-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M668-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9D8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9D8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6H0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6H0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TML4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TML4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P493", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P493", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P493-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P493-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MYZ0", "url": "https://www.uniprot.org/uniprotkb/F1MYZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MYZ0-1", "url": "https://www.uniprot.org/uniprotkb/F1MYZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLPWWWELGDPCAWTGQGRGTRRMSPATTGTFLLTAFLLSCADGINGTVKWKTKQANNFIISRKMTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGKWYS", "length": 473, "header": "tr|A0A3Q1LK26-1|A0A3Q1LK26_BOVIN Isoform 1 of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=2 CANONICAL=A0A3Q1LK26-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26/entry", "sequence": { "sequence": "MQLPWWWELGDPCAWTGQGRGTRRMSPATTGTFLLTAFLLSCADGINGTVKWKTKQANNFIISRKMTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGKWYS", "length": 473, "header": "tr|A0A3Q1LK26-1|A0A3Q1LK26_BOVIN Isoform 1 of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=2 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12063661, "end_pos": 11992911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066455.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066455.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059874.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059874.2" } ] } }, { "isoform_ac": "A0A3Q1M668-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M668/entry", "sequence": { "sequence": "MLIPVPLKVRHMSMTFLLSCADGINGTVKWKTKQANNFIISRKMTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGKWYS", "length": 451, "header": "tr|A0A3Q1M668-1|A0A3Q1LK26_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=2 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12177351, "end_pos": 11992911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072667.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072667.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065453.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065453.2" } ] } }, { "isoform_ac": "A0AAA9S9D8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9D8/entry", "sequence": { "sequence": "MQLPWWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGEY", "length": 435, "header": "tr|A0AAA9S9D8-1|A0A3Q1LK26_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=1 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12063661, "end_pos": 11995802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096072.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096072.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081905.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081905.1" } ] } }, { "isoform_ac": "A0AAA9T6H0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6H0/entry", "sequence": { "sequence": "MQLPWWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGEY", "length": 426, "header": "tr|A0AAA9T6H0-1|A0A3Q1LK26_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=1 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12063661, "end_pos": 11995802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133909.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133909.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092334.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092334.1" } ] } }, { "isoform_ac": "A0AAA9TJA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA7/entry", "sequence": { "sequence": "MNTFSHVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGKWYS", "length": 407, "header": "tr|A0AAA9TJA7-1|A0A3Q1LK26_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=1 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12062682, "end_pos": 11992911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130365.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130365.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098538.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098538.1" } ] } }, { "isoform_ac": "A0AAA9TML4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TML4/entry", "sequence": { "sequence": "MPFLYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGKWYS", "length": 404, "header": "tr|A0AAA9TML4-1|A0A3Q1LK26_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=1 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12037803, "end_pos": 11992911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121820.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121820.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098482.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098482.1" } ] } }, { "isoform_ac": "A0AAA9TW73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW73/entry", "sequence": { "sequence": "MQLPWWWELGDPCAWTGQGRGTRRMSPATTGTFLLTGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGDFRLTTFQRFEVNGIPEERKLTEAMNL", "length": 410, "header": "tr|A0AAA9TW73-1|A0A3Q1LK26_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=1 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12063661, "end_pos": 11992877, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098300.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098300.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102578.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102578.1" } ] } }, { "isoform_ac": "A0ABI0P493-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P493/entry", "sequence": { "sequence": "MTAGKKDVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGKWYS", "length": 408, "header": "tr|A0ABI0P493-1|A0ABI0P493_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=1 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12046782, "end_pos": 11992911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136336.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136336.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106215.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106215.1" } ] } }, { "isoform_ac": "F1MYZ0-1", "url": "https://www.uniprot.org/uniprotkb/F1MYZ0/entry", "sequence": { "sequence": "MQLPWWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYTIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTVIECQLWLRLLPGLSCCSEKEYFITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDRTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYESTNMPLMQTQQNLPHQTQIPQQQTTGDFRLTTFQRFEVNGIPEERKLTEAMNL", "length": 471, "header": "tr|F1MYZ0-1|F1MYZ0_BOVIN Computationally mapped isoform of Epsilon-sarcoglycan OS=Bos taurus OX=9913 GN=SGCE PE=3 SV=2 CANONICAL=A0A3Q1LK26-1" }, "locus": { "chromosome": "4", "start_pos": 12063661, "end_pos": 11992877, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028355.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028355.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028355.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028355.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ], "pmid": "" }, { "name": "sarcoglycan complex", "id": "GO:0016012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016012", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LK26-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 473, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LK26-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LK26" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LK26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK26" }, { "id": "SM00736", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00736" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dystroglycan-type cadherin-like", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 193, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LK34-1", "uniprot_ac": "A0A3Q1LK34", "uniprot_id": "A0A3Q1LK34_BOVIN", "mass": { "chemical_mass": 43312.0, "monoisotopic_mass": 43312.0 }, "refseq": { "ac": "XP_024846068", "name": "interleukin-3 receptor subunit alpha isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846068" }, "gene_names": [ { "name": "IL3RA", "type": "recommended", "evidence": [ { "id": "A0A3Q1LK34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34" } ] }, { "name": "IL3RA", "type": "synonym", "evidence": [ { "id": "XP_024846068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846068" } ] }, { "name": "LOC132342083", "type": "synonym", "evidence": [ { "id": "A0A3Q1LK34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34" } ] } ], "protein_names": [ { "name": "Interleukin 3 receptor subunit alpha", "type": "synonym", "evidence": [ { "id": "A0A3Q1LK34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34/entry#names_and_taxonomy" } ] }, { "name": "interleukin-3 receptor subunit alpha isoform X3", "type": "synonym", "evidence": [ { "id": "XP_024846068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846068" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK34", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IL3RA", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34", "locus": { "chromosome": "3", "start_pos": 119500207, "end_pos": 119477383, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000049808", "url": "https://www.ensembl.org/id/ENSBTAG00000049808" } ] } } ], "crossref": [ { "id": "A0A3Q1LK34", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LK34", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049808", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100299249", "url": "https://www.ncbi.nlm.nih.gov/gene/100299249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LK34", "url": "https://www.orthodb.org/?gene=A0A3Q1LK34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-512988", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-512988", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-912526", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-912526", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024846068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK34", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPWLAVLLTLICCSMTTDHAISDPDPPIKNLRIDPERKRLAWDQHGNVSEIGCYVNSKILKKAIEKPYCSLGDLSCEVKNYTVKVIKGQPFSAWIQYPKQGNPLAAADNLTCRVHDVDQLSCSWAVGEEAPANVQYHFYLKHPLKTWPCPKYMQNQQGVNVQCHFDSLSLQPERQTLFRFLVNGTSGGSKIPCRQMTHRLEEIEILAAPNITKKWCNESYSFMEWEVRSLFTEDIKYELEIQKGTDLAYKEETELKVLGLRNPGPYTVKIKAMDSLFFESRPAGQWSAPQHLDCGRKDASFPIWLVYLLAPLGALLLVGLVFLCRRWPLMQKLFPRVPHVKDPVGDSFQNERMMAWDPEQQSQEECPVVRVQVLGET", "length": 379, "header": "tr|A0A3Q1LK34-1|A0A3Q1LK34_BOVIN Isoform 1 of Interleukin 3 receptor subunit alpha OS=Bos taurus OX=9913 GN=IL3RA PE=4 SV=3 CANONICAL=A0A3Q1LK34-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK34/entry", "sequence": { "sequence": "MALPWLAVLLTLICCSMTTDHAISDPDPPIKNLRIDPERKRLAWDQHGNVSEIGCYVNSKILKKAIEKPYCSLGDLSCEVKNYTVKVIKGQPFSAWIQYPKQGNPLAAADNLTCRVHDVDQLSCSWAVGEEAPANVQYHFYLKHPLKTWPCPKYMQNQQGVNVQCHFDSLSLQPERQTLFRFLVNGTSGGSKIPCRQMTHRLEEIEILAAPNITKKWCNESYSFMEWEVRSLFTEDIKYELEIQKGTDLAYKEETELKVLGLRNPGPYTVKIKAMDSLFFESRPAGQWSAPQHLDCGRKDASFPIWLVYLLAPLGALLLVGLVFLCRRWPLMQKLFPRVPHVKDPVGDSFQNERMMAWDPEQQSQEECPVVRVQVLGET", "length": 379, "header": "tr|A0A3Q1LK34-1|A0A3Q1LK34_BOVIN Isoform 1 of Interleukin 3 receptor subunit alpha OS=Bos taurus OX=9913 GN=IL3RA PE=4 SV=3 CANONICAL=A0A3Q1LK34-1" }, "locus": { "chromosome": "3", "start_pos": 119499184, "end_pos": 119484591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085850.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085850.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056952.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056952.3" } ] } } 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"uniprot_canonical_ac": "A0A3Q1LK48-1", "uniprot_ac": "A0A3Q1LK48", "uniprot_id": "A0A3Q1LK48_BOVIN", "mass": { "chemical_mass": 57051.0, "monoisotopic_mass": 57051.0 }, "refseq": {}, "gene_names": [ { "name": "CYP3A76", "type": "recommended", "evidence": [ { "id": "A0A3Q1LK48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK48" } ] } ], "protein_names": [ { "name": "Cytochrome P450 3A", "type": "recommended", "evidence": [ { "id": "A0A3Q1LK48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK48/entry#names_and_taxonomy" } ] }, { "name": "1.14.14.-", "type": "synonym", "evidence": [ { "id": "A0A3Q1LK48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK48/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cytochromes P450 are a group of heme-thiolate monooxygenases. 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"categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LK48", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK48-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0C7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0C7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0C7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELIPNFSVETWVLLAISLVLLYLYGTYSHGLFKKLGVPGPRPLPLFGNVLSYRKGVCEFDEECFKKYGKMWGIFEGKQPLLVITDPDMIKTVLVKECYSVFTNRRVFGPSGVMKNAISVAEDEQWKRIRTLLSPTFTSGKLKEMFPIIGKYGDVLVRNLRKEAEKGTSVDIKDIFGAYSMDVITSTSFGVNIDSLGNPQDPFVENVKKLLRFSILDPFLLAVVLFPFLVPILDVLNITIFPKSAVNFFTKSVKRIKESRLKDNQKPRVDFLQLMINSQNSKETDNHKALSDQELIAQSIIFIFAGYETTSSTLSFLLYILATHPDVQQKLQEEIDATFPNKAPPTYDVLAQMEYLDMVVNETLRMFPIAIRLERLCKKDVEIHGVSIPKGTTVMVPISVLHKDPQLWPEPEEFRPERFSKKNKDSINPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSFKPCKETQIPLKISSQGVLRPEKPVVLKVVLRDGTISGA", "length": 503, "header": "tr|A0A3Q1LK48-1|A0A3Q1LK48_BOVIN Isoform 1 of Cytochrome P450 3A OS=Bos taurus OX=9913 GN=CYP3A76 PE=1 SV=2 CANONICAL=A0A3Q1LK48-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK48-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK48/entry", "sequence": { "sequence": "MELIPNFSVETWVLLAISLVLLYLYGTYSHGLFKKLGVPGPRPLPLFGNVLSYRKGVCEFDEECFKKYGKMWGIFEGKQPLLVITDPDMIKTVLVKECYSVFTNRRVFGPSGVMKNAISVAEDEQWKRIRTLLSPTFTSGKLKEMFPIIGKYGDVLVRNLRKEAEKGTSVDIKDIFGAYSMDVITSTSFGVNIDSLGNPQDPFVENVKKLLRFSILDPFLLAVVLFPFLVPILDVLNITIFPKSAVNFFTKSVKRIKESRLKDNQKPRVDFLQLMINSQNSKETDNHKALSDQELIAQSIIFIFAGYETTSSTLSFLLYILATHPDVQQKLQEEIDATFPNKAPPTYDVLAQMEYLDMVVNETLRMFPIAIRLERLCKKDVEIHGVSIPKGTTVMVPISVLHKDPQLWPEPEEFRPERFSKKNKDSINPYVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSFKPCKETQIPLKISSQGVLRPEKPVVLKVVLRDGTISGA", "length": 503, "header": "tr|A0A3Q1LK48-1|A0A3Q1LK48_BOVIN Isoform 1 of Cytochrome P450 3A OS=Bos taurus OX=9913 GN=CYP3A76 PE=1 SV=2 CANONICAL=A0A3Q1LK48-1" }, "locus": { "chromosome": "25", "start_pos": 36691476, "end_pos": 36584533, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077421.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077421.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059906.2", "url": 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[provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377158", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377158" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2L2C", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2", "locus": { "chromosome": "7", "start_pos": 41792105, "end_pos": 41791167, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000067939", "url": "https://www.ensembl.org/id/ENSBTAG00000067939" } ] } } ], "crossref": [ { "id": "A0A3Q1LKI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LKI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616716", "url": "https://www.ncbi.nlm.nih.gov/gene/616716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616716", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGNYNQT", "url": "https://omabrowser.org/oma/group/MGNYNQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKI2", "url": "https://www.orthodb.org/?gene=A0A3Q1LKI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377158", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377158", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNYNQTSTDFILLGLFPSSRTGLFLFILIGFIFLMALVGNLSMILLIFLDIRLHKPMYFLLSQLSLMDLNYISTTVPKMAYDFLFANKSISIIGCGIQSFFFLTMACAEGLLLASMAYDRYVAICFPLHYPIRISRKVCILMITGSWIMGSINSCAHTTYILSIPYCQSRSINHFFCDVTVMLTIACIDITVYEYTVFLSTTLFLLLPFIGIAFSYGRVLLAVYCMNSAEGKKKAYSTCSTHLTVVSFYYAPFVYTYLRPRFLRTPTEDKVLAVFYIILTPMLNPIIYSLRNKEVIGALRRVTQRISPMKM", "length": 312, "header": "tr|A0A3Q1LKI2-1|A0A3Q1LKI2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2L2C PE=3 SV=1 CANONICAL=A0A3Q1LKI2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2/entry", "sequence": { "sequence": "MGNYNQTSTDFILLGLFPSSRTGLFLFILIGFIFLMALVGNLSMILLIFLDIRLHKPMYFLLSQLSLMDLNYISTTVPKMAYDFLFANKSISIIGCGIQSFFFLTMACAEGLLLASMAYDRYVAICFPLHYPIRISRKVCILMITGSWIMGSINSCAHTTYILSIPYCQSRSINHFFCDVTVMLTIACIDITVYEYTVFLSTTLFLLLPFIGIAFSYGRVLLAVYCMNSAEGKKKAYSTCSTHLTVVSFYYAPFVYTYLRPRFLRTPTEDKVLAVFYIILTPMLNPIIYSLRNKEVIGALRRVTQRISPMKM", "length": 312, "header": "tr|A0A3Q1LKI2-1|A0A3Q1LKI2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2L2C PE=3 SV=1 CANONICAL=A0A3Q1LKI2-1" }, "locus": { "chromosome": "7", "start_pos": 41792102, "end_pos": 41791167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080358.1", "url": "https://www.ensembl.org/id/ENSBTAT00000080358.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057178.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057178.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616716", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TVG1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100521607", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKYNQTSTDFILLGLLPPERIGFFLFILIVLIFLMTLFGNLSMILLIILDTQLHTPMYFLLSQLSFMDLNYISTIVPKMAYNYLIGNKSISFIGCGVQSFFFLTLGGAEALILAAMAYDRYVAICFPLHYPIRISRRVCVLMIMGSWIMGSINSCAHTIYILHIPYCRSRAINHFFCDVPAMLTLACMDTWIHEYTVFVSTILFLLLPFIGIACSYGRVLLAVYHMRSDEGKKKAYSTCSTHLTVVTFYYAPFAYTYLRPKFLRAPTEDKALAVFYTILTPILNPLIYSLRNKEVMGALRRVTQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A3Q1LKI2", "url": "https://omabrowser.org/oma/group/A0A3Q1LKI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LKI2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LKI2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LKI2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LKI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LKM4-1", "uniprot_ac": "A0A3Q1LKM4", "uniprot_id": "A0A3Q1LKM4_BOVIN", "mass": { "chemical_mass": 105869.0, "monoisotopic_mass": 105869.0 }, "refseq": { "ac": "XP_002694494", "name": "ankyrin repeat and LEM domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694494" }, "gene_names": [ { "name": "ANKLE2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LKM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4" } ] }, { "name": "ANKLE2", "type": "synonym", "evidence": [ { "id": "XP_002694494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694494" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and LEM domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LKM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4/entry#names_and_taxonomy" } ] }, { "name": "LEM domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "A0A3Q1LKM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and LEM domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_002694494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694494" } ] } ], "function": [ { "annotation": "Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. May regulate nuclear localization of VRK1 in non-dividing cells. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. Involved in brain development.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4#function" }, { "database": "UniProtKB", "id": "ARBA00056222", "url": "https://www.uniprot.org/uniprotkb/ARBA00056222#function" }, { "database": "UniProtKB", "id": "E1BFD1", "url": "https://www.uniprot.org/uniprotkb/E1BFD1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANKLE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4", "locus": { "chromosome": "17", "start_pos": 44500872, "end_pos": 44477129, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000033339", "url": "https://www.ensembl.org/id/ENSBTAG00000033339" } ] } } ], "crossref": [ { "id": "A0A3Q1LKM4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LKM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000033339", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000033339", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12944", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12944", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540159", "url": "https://www.ncbi.nlm.nih.gov/gene/540159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540159", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LKM4", "url": "https://www.orthodb.org/?gene=A0A3Q1LKM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BFD1", "url": "https://www.orthodb.org/?gene=E1BFD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12349:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12349:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2995383", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2995383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002694494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKM4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFD1", "url": "https://www.uniprot.org/uniprotkb/E1BFD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFD1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"tr|A0A3Q1LKM4-1|A0A3Q1LKM4_BOVIN Isoform 1 of Ankyrin repeat and LEM domain-containing protein 2 OS=Bos taurus OX=9913 GN=ANKLE2 PE=3 SV=2 CANONICAL=A0A3Q1LKM4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM4/entry", "sequence": { "sequence": 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"tr|A0A3Q1LKM4-1|A0A3Q1LKM4_BOVIN Isoform 1 of Ankyrin repeat and LEM domain-containing protein 2 OS=Bos taurus OX=9913 GN=ANKLE2 PE=3 SV=2 CANONICAL=A0A3Q1LKM4-1" }, "locus": { "chromosome": "17", "start_pos": 44499868, "end_pos": 44477328, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083810.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083810.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057260.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057260.2" } ] } }, { "isoform_ac": "E1BFD1-1", "url": "https://www.uniprot.org/uniprotkb/E1BFD1/entry", "sequence": { "sequence": 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"Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:112444619", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112444619", "resource": "KEGG Pathway" }, { "id": "R-BTA-1461957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1461957", "resource": "Reactome", "description": "Beta defensins" }, { "id": "R-BTA-1461973", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1461973", "resource": "Reactome", "description": "Defensins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKM9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chemoattractant activity", "id": "GO:0042056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042056", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKM9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM9" } ], "pmid": "" }, { "name": "CCR6 chemokine receptor binding", "id": "GO:0031731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031731", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKM9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKM9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM9" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKM9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LKM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 79, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LKM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LKM9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 71 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LKQ6-1", "uniprot_ac": "A0A3Q1LKQ6", "uniprot_id": "A0A3Q1LKQ6_BOVIN", "mass": { "chemical_mass": 98346.0, "monoisotopic_mass": 98346.0 }, "refseq": {}, "gene_names": [ { "name": "USP6NL", "type": "recommended", "evidence": [ { "id": "A0A3Q1LKQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ] } ], "protein_names": [ { "name": "USP6 N-terminal-like protein", "type": "recommended", "evidence": [ { "id": "A0A3Q1LKQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a GTPase-activating protein for RAB43, RAB5A and RAB30. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MGE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGE2#function" }, { "database": "UniProtKB", "id": "ARBA00094364", "url": "https://www.uniprot.org/uniprotkb/ARBA00094364#function" }, { "database": "UniProtKB", "id": "A0AAA9SNJ7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNJ7#function" }, { "database": "UniProtKB", "id": "A0AAA9SSE8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSE8#function" }, { "database": "UniProtKB", "id": "A0AAA9T8J8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8J8#function" }, { "database": "UniProtKB", "id": "A0AAA9TBQ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBQ1#function" }, { "database": "UniProtKB", "id": "E1B7U3", "url": "https://www.uniprot.org/uniprotkb/E1B7U3#function" }, { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "USP6NL", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6", "locus": { "chromosome": "13", "start_pos": 12775997, "end_pos": 12639936, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019488", "url": "https://www.ensembl.org/id/ENSBTAG00000019488" } ] } } ], "crossref": [ { "id": "A0A3Q1LKQ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LKQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019488", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019488", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "530462", "url": "https://www.ncbi.nlm.nih.gov/gene/530462", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:530462", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530462", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFVPRWN", "url": "https://omabrowser.org/oma/group/EFVPRWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKQ6", "url": "https://www.orthodb.org/?gene=A0A3Q1LKQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MGE2", "url": "https://www.orthodb.org/?gene=A0A3Q1MGE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1B7U3", "url": "https://www.orthodb.org/?gene=E1B7U3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNJ7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSE8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8J8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8J8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBQ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B7U3", "url": "https://www.uniprot.org/uniprotkb/E1B7U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B7U3-1", "url": "https://www.uniprot.org/uniprotkb/E1B7U3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSSEKHWTADLGVAPDRDHIQRHLQSWRPCGVVKSTLEPYCLGLNANSATSKLYSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLL", "length": 867, "header": "tr|A0A3Q1LKQ6-1|A0A3Q1LKQ6_BOVIN Isoform 1 of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=2 CANONICAL=A0A3Q1LKQ6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6/entry", "sequence": { "sequence": "MYSSEKHWTADLGVAPDRDHIQRHLQSWRPCGVVKSTLEPYCLGLNANSATSKLYSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLL", "length": 867, "header": "tr|A0A3Q1LKQ6-1|A0A3Q1LKQ6_BOVIN Isoform 1 of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=2 CANONICAL=A0A3Q1LKQ6-1" }, "locus": { "chromosome": "13", "start_pos": 12772892, "end_pos": 12655692, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087030.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087030.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057057.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057057.2" } ] } }, { "isoform_ac": "A0A3Q1MGE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGE2/entry", "sequence": { "sequence": "MDSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLLSFRCLCFQDV", "length": 824, "header": "tr|A0A3Q1MGE2-1|A0A3Q1LKQ6_BOVIN Computationally mapped isoform of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=2 CANONICAL=A0A3Q1LKQ6-1" }, "locus": { "chromosome": "13", "start_pos": 12775712, "end_pos": 12655772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078752.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078752.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068075.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068075.2" } ] } }, { "isoform_ac": "A0AAA9SNJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNJ7/entry", "sequence": { "sequence": "MSDSVRPRRRKPTRLPHPWDSPDSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLL", "length": 835, "header": "tr|A0AAA9SNJ7-1|A0A3Q1LKQ6_BOVIN Computationally mapped isoform of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=1 CANONICAL=A0A3Q1LKQ6-1" }, "locus": { "chromosome": "13", "start_pos": 12772892, "end_pos": 12671114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116788.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116788.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084433.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084433.1" } ] } }, { "isoform_ac": "A0AAA9SSE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSE8/entry", "sequence": { "sequence": "MERRVPAEGDWIFAGPEAEERKGGEDSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLL", "length": 838, "header": "tr|A0AAA9SSE8-1|A0A3Q1LKQ6_BOVIN Computationally mapped isoform of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=1 CANONICAL=A0A3Q1LKQ6-1" }, "locus": { "chromosome": "13", "start_pos": 12772892, "end_pos": 12700329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133495.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133495.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086913.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086913.1" } ] } }, { "isoform_ac": "A0AAA9T8J8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8J8/entry", "sequence": { "sequence": "MRTEAVVNSQGQTGYLTKDSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLL", "length": 831, "header": "tr|A0AAA9T8J8-1|A0A3Q1LKQ6_BOVIN Computationally mapped isoform of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=1 CANONICAL=A0A3Q1LKQ6-1" }, "locus": { "chromosome": "13", "start_pos": 12772892, "end_pos": 12718484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112778.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112778.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095063.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095063.1" } ] } }, { "isoform_ac": "A0AAA9TBQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBQ1/entry", "sequence": { "sequence": "MDSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLL", "length": 814, "header": "tr|A0AAA9TBQ1-1|A0A3Q1LKQ6_BOVIN Computationally mapped isoform of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=1 CANONICAL=A0A3Q1LKQ6-1" }, "locus": { "chromosome": "13", "start_pos": 12772892, "end_pos": 12655772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127809.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127809.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094112.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094112.1" } ] } }, { "isoform_ac": "E1B7U3-1", "url": "https://www.uniprot.org/uniprotkb/E1B7U3/entry", "sequence": { "sequence": "MIQVLQIVKELVTPSRQRAARAKEDSNQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAMERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVHGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEVYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHRKHLMRLSMEELVEFLQETLAKDFFFEDDFVIEQLQISMAELKRAKLDLPEPGKEDEFPKKPLGQLPPEGQSAGVTHLSNGQRSVGRSSPHPGGRRGSGSPHKIHEPSPPHPRRTGTPERARQQRRKSSDEEGKRLRDEAQAQAQAQRRLPPGAQDGSGQYNHAAANQNSNATSRARKEFAPRWHKPSEAAVLEKTAKSAVEGRSRAAPPALADPRAPHVRQKTKVLDADEGKRGSTASQYDNVPEDGPGGAVEEALERARAQSPRRPAEPGASPSRAPPKFAFKVLPSSYAQHPFLPDGEDRGPAHPPSYSNPPTYQGSSPKRVPAANSSFPFPPGAHTNPSRRPYGSTLSISASPEKSYSRPTPLVQPSSRIEVLPVDLGAGGYSGNSGSPKNGRFILPPGDCLPDNRKWSEVGYTWRPEMHGQPWTRDVNRGHLSSFPRHPTFHHAPYQDHSLPSVSVDGPVRYRTSPALEDATSPGFQYSGPSPPAYHYRNRDGLSMQESVLL", "length": 837, "header": "tr|E1B7U3-1|A0A3Q1LKQ6_BOVIN Computationally mapped isoform of USP6 N-terminal-like protein OS=Bos taurus OX=9913 GN=USP6NL PE=4 SV=3 CANONICAL=A0A3Q1LKQ6-1" }, "locus": { "chromosome": "13", "start_pos": 12772892, "end_pos": 12676080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025957.8", "url": "https://www.ensembl.org/id/ENSBTAT00000025957.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025957.6", "url": "https://www.ensembl.org/id/ENSBTAP00000025957.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:530462", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530462", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GYI0-1", "protein_name": "USP6 N-terminal-like protein", "gene_name": "Usp6nl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVEDTDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNATADRQKQLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARACSPDIRQIDLDVNRTFRNHIMFRDRYGVKQQSLFHVLAAYSVYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSHEIYTSFYTMKWFFQCFLDRTPFTLTLRIWDIYIFEGERVLTAMSYTILKLHRKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQVSMSELKRAKLDLPEPGKEDEYPKKPLGQLPPESNSACINQLSNGQRSVGRPSPQSNRRESGSPHKKHEHSPAHHSRTGTPERVRQPRRKSGDEDSKNLKHEADFQRKPTSGPQDSSRHYNHAAANQNSNAISNIRKEFMPKWKKPSDASAFERTAKYAFEGKSHSVYPTPTVAIPSSAETRMSNSRQKMKVFDGSDGKRGSNASQYDNVPGSENENGVSVEEAPERTHPHSPRKHAEPSSSPSKVPSKFTFKGQPPSHVRYPSQLEGEDHRAAYPPSYSNPPVYHGNSPKHLPVAHSGFVSPQISPGTQINLSRRPYGSSLSVDISPEKSYSRPTPVVLPSSRIEVLPIDIGAGGYAGSSGSPKNGKFILPPVDYLPESRKWSEVSYSYRPEMHGQSWTRDASRSHFSNLPKYAAFQHLPFQDHGLPEVSVDSPVRYKTSPAVEDASPPGYQYTGPSPPAHHYRNREGLSIQESVLL", "length": 823 }, "evidence": [ { "id": "A0A3Q1LKQ6", "url": "https://omabrowser.org/oma/group/A0A3Q1LKQ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZL57-1", "protein_name": "USP6 N-terminal-like protein", "gene_name": "Usp6nl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYPNAAADRQKQLEIERTSKWLKMLKRWERYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFRLNLRIWDIYIFEGERILTAMSYTILKLHRKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQVSMTELKRAKLDLPEPGKEDEYPRKPLGQLPPEYTNHLSNGQRSVGRPSPKISSRREDGSPHKAHEHSPAHHSRNGTPERVGQSRRKSVDEGSKNLKQEADFQRKPSSGTQDNSKHYNHATANQNSNALSNIRKEFVPKWRKPSEASAIERTAKYAIEGRSHSVFPALSVAVPSSAETRLSNSRQKMKAFDGGEGNRGSNASQYDNVPGSESEPGASAEEGPERTHPHSPRKHSEPSPSPSKVPNKFTFKVQPPSHVRYPSQPAGEDHRAAYPPSYSNPPVYHGNSPKHIPTAHSGFASTQISLGPQVNPSRRPYGSSLSGDTSPEKSYGRLTPVLPSSRIEVLPIDIGARGYGSSGSPKSGKFILPPVDYLPENRKWSEFSYTYRPEVHGQSWTQDATRSHLSNLPKYTAFPHIPLQDHGLPEVSVDSPVRYKTSPAVEEASPPGYPYAGPTPSAHHYRNREGLSVQESVLL", "length": 816 }, "evidence": [ { "id": "A0A3Q1LKQ6", "url": "https://omabrowser.org/oma/group/A0A3Q1LKQ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XC3-1", "protein_name": "USP6 N-terminal-like protein", "gene_name": "Usp6nl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPYHNAAADRQKQLEIERTSKWLKMLKKWERYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFRLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFLQETLAKDFFFEDDFVIEQLQVSMAELKRAKLDLPEPGKEDEYPKKPLGQLPPESACVNHLSNGQRSVGRPSPKTSSRREDGSPRKNHEHSPVHHSRNGTPERAGQSRRKSVDEGSKNLKHEAESQRKPSPGMQDSSRHYNHAAANQNSNAISNVRKEFMPKWRKPSDASAIERTTKYAVEGKSHSALPALPVAIPGSAETRLPNSRQKMKALDGGEGKRGSNASQYDNVPGGESEHGASAEEGPERTHPHSPRKHPEPSPSPPKVPNKFTFKVQPPSHVRYPPQLPEEDHRAAYPPSYSNPPVYHGNSPKHVPTAHSGFVSTQISPRPQINPSRRPYGSSLSVDTSPEKAYSRPTPVVLPSSRIEVLPIDMGARGYGSSGSPKNGQFILPPVDYLPENRKWSEVSYTYRPEMHGQSWTRDAHRSHLSNLPNYAAFQHIPFQAHGLPEVSVDSPVRYKMSAAVEDASPPGYPYAGPSPSAHHYRNGEGLSVQESVLL", "length": 819 }, "evidence": [ { "id": "A0A3Q1LKQ6", "url": "https://omabrowser.org/oma/group/A0A3Q1LKQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92738-1", "protein_name": "USP6 N-terminal-like protein", "gene_name": "USP6NL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL", "length": 828 }, "evidence": [ { "id": "A0A3Q1LKQ6", "url": "https://omabrowser.org/oma/group/A0A3Q1LKQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "plasma membrane to endosome transport", "id": "GO:0048227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048227", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "regulation of Golgi organization", "id": "GO:1903358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903358", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" }, { "name": "retrograde transport, plasma membrane to Golgi", "id": "GO:0035526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035526", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKQ6" } ], "pmid": "" } ] } 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9Q7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0D4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0D4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T278", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T278", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T278-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T278-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQ84", "url": "https://www.uniprot.org/uniprotkb/F1MQ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQ84-1", "url": "https://www.uniprot.org/uniprotkb/F1MQ84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PTP7", "url": "https://www.uniprot.org/uniprotkb/F6PTP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PTP7-1", "url": "https://www.uniprot.org/uniprotkb/F6PTP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVSRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSIERLQKLLLEKDRLKFCIASMYRKNNDDPGAETKAGNGTVDISGLPDVRYSALLQEDFAYSGFECWVENEDQIQEHSCHASEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVAKSISCGPSTRWSTSICTEEPALSEVGPPDLPNAKVPPDGESMEEGTPGSSVESLDASIQASPPQPKDEEPERSAKELAKCDCCSDEQAPQHTCNHKLELALSMIKGLDYKPIQSPRGSKLPIPVKSNPSGTRPGHIMTDGVSSGFLNRSLKPLYKTPVSYPLEISDLQELWDDLCEDYLPLRVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQETSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFTGGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSDSIHHSSHSAVLSSKPSATSSSQEVKAEPSSNPVSFPAPQNPPKEASQAHPGLHFQSIPTLVSLPQAPLPSAPPSFLPFSSAGPPLPGCCETPMVSLAEAQQELQMLRKQLGESVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKAYTWDACHQVPLSSDLSHLVAEIRALRGQLEQSIQVNNCLRLQLEQQLDGGASKAGLSSSSVNQKFPTNTDPGNKQPFFQDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEPQGCPWLLPLSQVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEVKSLRALPCTPVL", "length": 2520, "header": "tr|A0A3Q1LKW4-1|A0A3Q1LKW4_BOVIN Isoform 1 of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=2 CANONICAL=A0A3Q1LKW4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4/entry", "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVSRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSIERLQKLLLEKDRLKFCIASMYRKNNDDPGAETKAGNGTVDISGLPDVRYSALLQEDFAYSGFECWVENEDQIQEHSCHASEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVAKSISCGPSTRWSTSICTEEPALSEVGPPDLPNAKVPPDGESMEEGTPGSSVESLDASIQASPPQPKDEEPERSAKELAKCDCCSDEQAPQHTCNHKLELALSMIKGLDYKPIQSPRGSKLPIPVKSNPSGTRPGHIMTDGVSSGFLNRSLKPLYKTPVSYPLEISDLQELWDDLCEDYLPLRVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQETSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFTGGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSDSIHHSSHSAVLSSKPSATSSSQEVKAEPSSNPVSFPAPQNPPKEASQAHPGLHFQSIPTLVSLPQAPLPSAPPSFLPFSSAGPPLPGCCETPMVSLAEAQQELQMLRKQLGESVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKAYTWDACHQVPLSSDLSHLVAEIRALRGQLEQSIQVNNCLRLQLEQQLDGGASKAGLSSSSVNQKFPTNTDPGNKQPFFQDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEPQGCPWLLPLSQVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEVKSLRALPCTPVL", "length": 2520, "header": "tr|A0A3Q1LKW4-1|A0A3Q1LKW4_BOVIN Isoform 1 of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=2 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 22905822, "end_pos": 22828067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076768.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076768.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057107.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057107.2" } ] } }, { "isoform_ac": "A0A3Q1M6Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Q9/entry", "sequence": { "sequence": "MKRIDSGSCCRRRCDCGCCCRAVRRAHHAPYWSRDAARIPPSSRQSPGRERRHPEPAGSWAAAAEEEEAAAAAAPWMRDYFAEDDGEMVPRTSHAAAFLSDTKDRGPPLQSQTWRSGDKIPLGHSLRAFERPLQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRDDIYKRNIELKVEVESLKRELQDKRQHPDKTCADAENINSHNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKEREDVPGDRVKSDQYTEALAQRDKKIEELSQSLAAQEKLVEQLSQEKQQLLHLLEEPADMEVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGGNLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFSGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSGLHFQSIPTLVSLPQAPLPSAPPSFLPFSSAGPPLPGCCETPMVSLAEAQQELQMLRKQLGESVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESGSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKAYTWDACHQVPLSSDLSHLVAEIRALRGQLEQSIQVNNCLRLQLEQQLDGGASKAGLSSSSVNQKFPTNTDPGNKQPFFQDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEVKSLRALPCTPVL", "length": 2422, "header": "tr|A0A3Q1M6Q9-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=2 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 23065535, "end_pos": 22828067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082210.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082210.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064025.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064025.2" } ] } }, { "isoform_ac": "A0A3Q1MKR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKR4/entry", "sequence": { "sequence": "MEQAWTRDYFAEDDGEMVPRTSHAAAFLSDTKDRGPPLQSQTWRSGDKIPLGHSLRAFERPLQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRDDIYKRNIELKVEVESLKRELQDKRQHPDKTCADAENINSHNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKEREDVPGDRVKSDQYTEALAQRDKKIEELSQSLAAQEKLVEQLSQEKQQLLHLLEEPADMEVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGGNLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFTGGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSDSIHHSSHSAVLSSKPSATSSSQEVKAEPSSNPVSFPAPQNPPKEASQAHPGLHFQSIPTLVSLPQAPLPSAPPSFLPFSSAGPPLPGCCETPMVSLAEAQQELQMLRKQLGESVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESGSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKAYTWDACHQVPLSSDLSHLVAEIRALRGQLEQSIQVNNCLRLQLEQQLDGGASKAGLSSSSVNQKFPTNTDPGNKQPFFQDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEVKSLRALPCTPVL", "length": 2403, "header": "tr|A0A3Q1MKR4-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=1 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 23031005, "end_pos": 22828067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082827.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082827.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069836.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069836.2" } ] } }, { "isoform_ac": "A0AAA9S5F0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5F0/entry", "sequence": { "sequence": "MKRIDSGSCCRRRCDCGCCCRAVRRAHHAPYWSRDAARIPPSSRQSPGRERRHPEPAGSWAAAAEEEEAAAAAAPWMRDYFAEDDGEMVPRTSHAAAFLSDTKDRGPPLQSQTWRSGDKIPLGHSLRAFERPLQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRDDIYKRNIELKVEVESLKRELQDKRQHPDKTCADAENINSHNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKEREDVPGDRVKSDQYTEALAQRDKKIEELSQSLAAQEKLVEQLSQEKQQLLHLLEEPADMEVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGGNLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFTGGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSGVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESGSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEVKSLRALPCTPVL", "length": 2242, "header": "tr|A0AAA9S5F0-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=1 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 23065535, "end_pos": 22828067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101148.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101148.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077384.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077384.1" } ] } }, { "isoform_ac": "A0AAA9S9Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q7/entry", "sequence": { "sequence": "MQQKYEASRDDIYKRNIELKVEVESLKRELQDKRQHPDKTCADAENINSHNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKEREDVPGDRVKSDQYTEALAQRDKKIEELSQSLAAQEKLVEQLSQEKQQLLHLLEEPADMEVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQETSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFSGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSDSIHHSSHSAVLSSKPSATSSSQEVKAEPSSNPVSFPAPQNPPKEASQAHPGVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESGSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKAYTWDACHQVPLSSDLSHLVAEIRALRGQLEQSIQVNNCLRLQLEQQLDGGASKAGLSSSSVNQKFPTNTDPGNKQPFFQDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEKTSYKTASVKPYSCPSKGEIPKGPAMHSSPVTLAFQETCKKRSHQRSLKQQEGWACAPSSQLPVC", "length": 2304, "header": "tr|A0AAA9S9Q7-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=1 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 22973943, "end_pos": 22827963, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089843.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089843.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078880.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078880.1" } ] } }, { "isoform_ac": "A0AAA9T0D4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0D4/entry", "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVSRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSIERLQKLLLEKDRLKFCIASMYRKNNDDPGAETKAGNGTVDISGLPDVRYSALLQEDFAYSGFECWVENEDQIQEHSCHASEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVAKSISCGPSTRWSTSICTEEPALSEVGPPDLPNAKVPPDGESMEEGTPGSSVESLDASIQASPPQPKDEEPERSAKELAKCDCCSDEQAPQHTCNHKLELALSMIKGLDYKPIQSPRGSKLPIPVKSNPSGTRPGHIMTDGVSSGFLNRSLKPLYKTPVSYPLEISDLQELWDDLCEDYLPLRVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGQETSGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFTGGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSDSIHHSSHSAVLSSKPSATSSSQEVKAEPSSNPVSFPAPQNPPKEASQAHPGVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESGSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKAYTWDACHQVPLSSDLSHLVAEIRALRGQLEQSIQVNNCLRLQLEQQLDGGASKAGLSSSSVNQKFPTNTDPGNKQPFFQDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEPQGCPWLLPLSQVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEVKSLRALPCTPVL", "length": 2459, "header": "tr|A0AAA9T0D4-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=1 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 22905822, "end_pos": 22828067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096219.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096219.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089846.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089846.1" } ] } }, { "isoform_ac": "A0AAA9T278-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T278/entry", "sequence": { "sequence": "MKRIDSGSCCRRRCDCGCCCRAVRRAHHAPYWSRDAARIPPSSRQSPGRERRHPEPAGSWAAAAEEEEAAAAAAPWMRDYFAEDDGEMVPRTSHAAAFLSDTKDRGPPLQSQTWRSGDKIPLGHSLRAFERPLQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRDDIYKRNIELKVEVESLKRELQDKRQHPDKTCADAENINSHNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKEREDVPGDRVKSDQYTEALAQRDKKIEELSQSLAAQEKLVEQLSQEKQQLLHLLEEPADMEVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGGNLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFTGGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSDSIHHSSHSAVLSSKPSATSSSQEVKAEPSSNPVSFPAPQNPPKEASQAHPGLHFQSIPTLVSLPQAPLPSAPPSFLPFSSAGPPLPGCCETPMVSLAEAQQELQMLRKQLGESVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESGSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKAYTWDACHQVPLSSDLSHLVAEIRALRGQLEQSIQVNNCLRLQLEQQLDGGASKAGLSSSSVNQKFPTNTDPGNKQPFFQDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEVKSLRALPCTPVL", "length": 2474, "header": "tr|A0AAA9T278-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=1 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 23065535, "end_pos": 22828067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111031.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111031.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090735.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090735.1" } ] } }, { "isoform_ac": "F1MQ84-1", "url": "https://www.uniprot.org/uniprotkb/F1MQ84/entry", "sequence": { "sequence": "MKRIDSGSCCRRRCDCGCCCRAVRRAHHAPYWSRDAARIPPSSRQSPGRERRHPEPAGSWAAAAEEEEAAAAAAPWMRDYFAEDDGEMVPRTSHAAAFLSDTKDRGPPLQSQTWRSGDKIPLGHSLRAFERPLQVQTQALRDFEKNIELKVEVESLKRELQDKRQHPDKTCADAENINSHNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKEREDVPGDRVKSDQYTEALAQRDKKIEELSQSLAAQEKLVEQLSQEKQQLLHLLEEPADMEVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGGNLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQLIKVALEKSRAAVETQNVSPAPPTLTGGDGNRGLQEEMLHLRAEIHRHLEEKRKAEGELKELKAQIEEAGFSSVAHIRNTMLSLCLENAELKEQMGEAMSDGWEIEEDKEKGEAMVETVVAKGVLNENSLQAEFRKVQGKLKNARNIISLLKEQLVLSSKEGTSKLNPELLVHLAKEINRMNTELVYSPGKHQCLEEEGVTTRPCPRPQSLDLGAALTVDAHQLDNQPQTHDPGPQSEFSFSGSTKHLRSQLAQCKQRYQDLQEKLLISEATVFAQANQLEKYRVMFTGGSSVKQDSKQVQVDLQDLGYETCGRSENEAEREESTSPECEEHDSLRETVLMEGLCSKQGHLDSTMTSPPGKKPLESQPGKQEELRAYGKSEDISVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLKAVGALEGTSPHSVTDEDEGWLSDGTGAFYPPGLQAKKDLESLIQRVSQLEAQLPKTGTEGKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREHLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPCSSHALSDSQRSPSSSSFLSDELEACSDMDIASEYTHYEEKKASPGHSDSIHHSSHSAVLSSKPSATSSSQEVKAEPSSNPVSFPAPQNPPKEASQAHPGLHFQSIPTLVSLPQAPLPSAPPSFLPFSSAGPPLPGCCETPMVSLAEAQQELQMLRKQLGESVTSVHPASPATLPTNHTEARSSHYLNPPQPLCPPRGTTDLGRILEPGYLGSSGQWDVMRPQKGSISGDLSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLENRLSSTARESGSTSNFYSPGLESTPQLSNENRVLREENHRLQAQLSHVSREHSQETECLREALLTSRSRLQELEMELEHQKVDRQQLLEDLKEKQQEILHFQEERLSLQEKDSRLQRKLALLQQQCEEKQQLFQSLQSELQIYEALYGDSKKTLKDSVASPPVRDVGMNSPVLVFPSSSSAAPGPETTTFSRTNELGLDASPVMKNPRKLEGDATDGSFANKHGRHVIGHIDDYSALREQIGEGRLLVKKIASLVRPTCSFSGLEAPGIEVMGSEGIQELRSSATALHHRLEESASLLTMFWRAALPSSPGPVLVDKVGESMKKELLELRTKLSKQESLLQSTSERLKTANQQKESMEQFIFSQLTRTHDVLKKARTNLEETCKKRSHQRSLKQQEGWACAPSSQLPVC", "length": 2373, "header": "tr|F1MQ84-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=4 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 23065535, "end_pos": 22827963, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061284.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061284.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053335.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053335.4" } ] } }, { "isoform_ac": "F6PTP7-1", "url": "https://www.uniprot.org/uniprotkb/F6PTP7/entry", "sequence": { "sequence": "MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVSRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSIERLQKLLLEKDRLKFCIASMYRKNNDDPGAETKAGNGTVDISGLPDVRYSALLQEDFAYSGFECWVENEDQIQEHSCHASEGPGNRPRRCRGCAALRVADSDYEAICKVPRKVAKSISCGPSTRWSTSICTEEPALSEVGPPDLPNAKVPPDGESMEEGTPGSSVESLDASIQASPPQPKDEEPERSAKELAKCDCCSDEQAPQHTCNHKLELALSMIKGLDYKPIQSPRGSKLPIPVKSNPSGTRPGHIMTDGVSSGFLNRSLKPLYKTPVSYPLEISDLQELWDDLCEDYLPLRVQPMTEDLLKQQKLNSNETGTTQQSVSDSHLAELQEKIQQTETTNKMLQEKLNEMSYELKSAQESSQKQDDTIQNLKETLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLKQLHNSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRAVRQKERQLADARRCVRFVEAAAQEREQQKEASWKHNQELQKALQQLQGELQSKSQQLHTLEAEKYNEIRTQEQHIQHLHYSLSHKEQLLQEFRELLQYRNNSDKTLEANEMLLEKLRQRIQDRDVALERAIDEKFSSLEEKEKELRQLHLAMRERDHDLERLRGILSANEATMQSMESLLRSKGLEVEQLSATCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLTATLLCKLGPGQTEIVEELCQRLQQKERMLQDLLSDRNKQAVEYEMEIQGLLQSMSTREQESHAAAEKMVQALMERNSELQALRQYLGGKDFMMSQAPLSNRPAEVTSISPHLGEQTDQGSVHIPSRDDSTSLTAKGDASVPRSSLGEVDTVAGLEKELSNAKEELELMAKKERESRMELSALQSMVAVQEQELQVQAADMESLTRTIQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVESQGGNLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVIRNRLEEVLGRSLERLSRLETLAAIGGTAAGDDTEDASTEFTDSIEEEAAHNSHQQL", "length": 1124, "header": "tr|F6PTP7-1|A0A3Q1LKW4_BOVIN Computationally mapped isoform of Phosphodiesterase 4D interacting protein OS=Bos taurus OX=9913 GN=PDE4DIP PE=4 SV=3 CANONICAL=A0A3Q1LKW4-1" }, "locus": { "chromosome": "3", "start_pos": 22905822, "end_pos": 22867107, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052249.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052249.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047996.4", "url": "https://www.ensembl.org/id/ENSBTAP00000047996.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1103, "start_aa": "Thr", "end_pos": 1103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" }, { "name": "regulation of Golgi organization", "id": "GO:1903358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903358", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LKW4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1148, "end_pos": 1150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1934, "end_pos": 1936, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKW4" }, { "id": "PS51316", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olduvai", "eco_id": "ECO_0000259", "start_pos": 1714, "end_pos": 1805, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1103 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 1148, "end_pos": 1150 }, { "start_pos": 1934, "end_pos": 1936 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 623, "end_pos": 625 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LL07-1", "uniprot_ac": "A0A3Q1LL07", "uniprot_id": "A0A3Q1LL07_BOVIN", "mass": { "chemical_mass": 221519.0, "monoisotopic_mass": 221519.0 }, "refseq": {}, "gene_names": [ { "name": "MYH15", "type": "recommended", "evidence": [ { "id": "A0A3Q1LL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ] } ], "protein_names": [ { "name": "Myosin heavy chain 15", "type": "synonym", "evidence": [ { "id": "A0A3Q1LL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYH15", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07", "locus": { "chromosome": "1", "start_pos": 53111783, "end_pos": 53261345, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018399", "url": "https://www.ensembl.org/id/ENSBTAG00000018399" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018399", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018399", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14929", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14929", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LL07", "url": "https://www.orthodb.org/?gene=A0A3Q1LL07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5X4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5X4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5X4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLSELGEAAVFLRISKDELLLLQAMAFDGKKKCWIHDEKNAYVEAEIKGSGGDGRLLVETTDGKHLSVKEDEIQQMNPPEFEMIEDMAMLTHLNEASVLHALRRRYDHWMIYTYSGLSCVSINPHKQLPVYHKAVAAAYKGRRRSDAPPHIFAVANNAFQDMLHSRENQSILFTGESGAGKTVNTKHIIQYFATVATTGESKEKLETLQDQIKQVNPVLEAFGNAKTLRNDNSSRFGKFIRMHFCARGKLSSADINIYLLEKSRVIFQQPGERNYHIFYQILSGKKELRDVCLVSENPSDFHFCSHGTVAVESLDDAEELLATDQAMDILGFLPDEKYGSYKLAGAILHFGNMKFKQKPREEQVEADGTENAGKAAFLMGINSSELVKGLIHPRIKVGNEYVTRSQNVEQVTYAVGALSKSIYERMFKWLVARINRVLDAKLSRQFFIGILDITGFEMLDYNSLEQLCINFTNEKLQQFFNQHTLVLEQEEYRREGIDWVSIDFGLDLQACVDLVEKPMGIFSILEEECMFHQATDVTFNTKLFDNHFGKSVHFQKPKPDNKKKYEADFELVHYAGVVPYNISGWLEKNKDFLNETVVAIFQKSSNRLLANLFENYISTNTALQFGEKKRKKGASFQMVASLHKENLNKLMTKLKSTAPHFVRCINPNVNKTPGVMDPYLVLQQLRCNGVLEGITICREGFPHRLLYADFKQRYYILNPRVFPKSKFASNRKAAEELLDSLEIDHTQYRFGITKVLLKDGSLSKLEAMRDERLSKVFTLFQARVRGKLMQIKFQRILEERDALLLIQWNIRAFIAVKSWPWMRLFFEIKPLVRSAGMGKEGAGLKEECMQLQKALEKSESQREELKSKQVSLLQEKNDLLLQLQAERETLANVEEQCELLIKSKIQLEASVKALSARVEEEEEINSKLTARGQKLEDECSELKKEIDDLETLLAKSQKEKHATELKVKNLLEEVESLNEDVSKLHRAARAAQETHQQTLEDLRNEEEKVHTLSKAKLTLEQRVNELEGALEQESKARMNCEKEKCKVEGELKLNQESMDDLESRQLQLAEKLRRKELEMNQMRSKVENEKSLVAQLQKTVKEFQTQIQLLKEELEAERTTRAKVERERANLIRELEDMNERLEEAGGVSSAQLEITKKQETKFQKLRRDLEEATLHFEATSASLKKRHADSLAELESQVENLQQVKQTLEKDKSDLELEVNDLLIHVEQMTRAKANAEKLCSLYEERLKEANAKLDEVTQLANDVTAQKTKLRSENGELRKRLEEMEALINQLSREKSIFTLQIQDLKGQLAEETKSQSALAQAVKSAKRDCDLLREQYEEEQAAKAELLQALLKGNAEMVKWRTKYEDDTIQRAEDLEDAKKKLALRLQEAAEAMGVANARNASLERARLRLQLELGDTLSDLGQARSAAAALNQKQQHFDKSLDDWRRKHEESQAMLDAAKKEARALSIQLLELRHSYEEGTMSQEALRRENKHLKEEISNLTNQVREGKKNLSKMEKVKKQIEQEKNEVQMALEEAEGALERNESKVLRLQLELSDTKAELERKLSEKDEEIENFRKKQQCAIDSLQLSLDSEARCRIEATRLKRSMEGDLTEMELQLSCASRQASEATKSLGQLQTQVKDLQVQVDDSTCMNSELKEQVAVAERRNALLQAEVEELRSLQEQTERSRRLAEEELLEATEKINLFHAQNTSLLSQKKKLEVDVARMQKEAEEAMQGCQNAEEKAKKAATEVANMSEALKKEQDTNAHLERMRKNMEQTIKDLQERLDDAEQTAIVGNRKQIQKLESRVRELEAELESEVQRNSEAQRGAHRLERCLKELTHQVEEDKKNMSRMQTLMDNLQLKVQSYKQQIESAEAEASQYRSKYKKQQHELNEAKERAEIAESQVNKLKMKAKEFGKKVHEE", "length": 1927, "header": "tr|A0A3Q1LL07-1|A0A3Q1LL07_BOVIN Isoform 1 of Myosin heavy chain 15 OS=Bos taurus OX=9913 GN=MYH15 PE=3 SV=3 CANONICAL=A0A3Q1LL07-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07/entry", "sequence": { "sequence": "MDLSELGEAAVFLRISKDELLLLQAMAFDGKKKCWIHDEKNAYVEAEIKGSGGDGRLLVETTDGKHLSVKEDEIQQMNPPEFEMIEDMAMLTHLNEASVLHALRRRYDHWMIYTYSGLSCVSINPHKQLPVYHKAVAAAYKGRRRSDAPPHIFAVANNAFQDMLHSRENQSILFTGESGAGKTVNTKHIIQYFATVATTGESKEKLETLQDQIKQVNPVLEAFGNAKTLRNDNSSRFGKFIRMHFCARGKLSSADINIYLLEKSRVIFQQPGERNYHIFYQILSGKKELRDVCLVSENPSDFHFCSHGTVAVESLDDAEELLATDQAMDILGFLPDEKYGSYKLAGAILHFGNMKFKQKPREEQVEADGTENAGKAAFLMGINSSELVKGLIHPRIKVGNEYVTRSQNVEQVTYAVGALSKSIYERMFKWLVARINRVLDAKLSRQFFIGILDITGFEMLDYNSLEQLCINFTNEKLQQFFNQHTLVLEQEEYRREGIDWVSIDFGLDLQACVDLVEKPMGIFSILEEECMFHQATDVTFNTKLFDNHFGKSVHFQKPKPDNKKKYEADFELVHYAGVVPYNISGWLEKNKDFLNETVVAIFQKSSNRLLANLFENYISTNTALQFGEKKRKKGASFQMVASLHKENLNKLMTKLKSTAPHFVRCINPNVNKTPGVMDPYLVLQQLRCNGVLEGITICREGFPHRLLYADFKQRYYILNPRVFPKSKFASNRKAAEELLDSLEIDHTQYRFGITKVLLKDGSLSKLEAMRDERLSKVFTLFQARVRGKLMQIKFQRILEERDALLLIQWNIRAFIAVKSWPWMRLFFEIKPLVRSAGMGKEGAGLKEECMQLQKALEKSESQREELKSKQVSLLQEKNDLLLQLQAERETLANVEEQCELLIKSKIQLEASVKALSARVEEEEEINSKLTARGQKLEDECSELKKEIDDLETLLAKSQKEKHATELKVKNLLEEVESLNEDVSKLHRAARAAQETHQQTLEDLRNEEEKVHTLSKAKLTLEQRVNELEGALEQESKARMNCEKEKCKVEGELKLNQESMDDLESRQLQLAEKLRRKELEMNQMRSKVENEKSLVAQLQKTVKEFQTQIQLLKEELEAERTTRAKVERERANLIRELEDMNERLEEAGGVSSAQLEITKKQETKFQKLRRDLEEATLHFEATSASLKKRHADSLAELESQVENLQQVKQTLEKDKSDLELEVNDLLIHVEQMTRAKANAEKLCSLYEERLKEANAKLDEVTQLANDVTAQKTKLRSENGELRKRLEEMEALINQLSREKSIFTLQIQDLKGQLAEETKSQSALAQAVKSAKRDCDLLREQYEEEQAAKAELLQALLKGNAEMVKWRTKYEDDTIQRAEDLEDAKKKLALRLQEAAEAMGVANARNASLERARLRLQLELGDTLSDLGQARSAAAALNQKQQHFDKSLDDWRRKHEESQAMLDAAKKEARALSIQLLELRHSYEEGTMSQEALRRENKHLKEEISNLTNQVREGKKNLSKMEKVKKQIEQEKNEVQMALEEAEGALERNESKVLRLQLELSDTKAELERKLSEKDEEIENFRKKQQCAIDSLQLSLDSEARCRIEATRLKRSMEGDLTEMELQLSCASRQASEATKSLGQLQTQVKDLQVQVDDSTCMNSELKEQVAVAERRNALLQAEVEELRSLQEQTERSRRLAEEELLEATEKINLFHAQNTSLLSQKKKLEVDVARMQKEAEEAMQGCQNAEEKAKKAATEVANMSEALKKEQDTNAHLERMRKNMEQTIKDLQERLDDAEQTAIVGNRKQIQKLESRVRELEAELESEVQRNSEAQRGAHRLERCLKELTHQVEEDKKNMSRMQTLMDNLQLKVQSYKQQIESAEAEASQYRSKYKKQQHELNEAKERAEIAESQVNKLKMKAKEFGKKVHEE", "length": 1927, "header": "tr|A0A3Q1LL07-1|A0A3Q1LL07_BOVIN Isoform 1 of Myosin heavy chain 15 OS=Bos taurus OX=9913 GN=MYH15 PE=3 SV=3 CANONICAL=A0A3Q1LL07-1" }, "locus": { "chromosome": "1", "start_pos": 53272202, "end_pos": 53112786, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080788.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080788.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060423.3", "url": "https://www.ensembl.org/id/ENSBTAP00000060423.3" } ] } }, { "isoform_ac": "A0ABI0P5X4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5X4/entry", "sequence": { "sequence": "MDILGFLPDEKYGSYKLAGAILHFGNMKFKQKPREEQVEADGTENAGKAAFLMGINSSELVKGLIHPRIKVGNEYVTRSQNVEQVTYAVGALSKSIYERMFKWLVARINRVLDAKLSRQFFIGILDITGFEMLDYNSLEQLCINFTNEKLQQFFNQHTLVLEQEEYRREGIDWVSIDFGLDLQACVDLVEKPMGIFSILEEECMFHQATDVTFNTKLFDNHFGKSVHFQKPKPDNKKKYEADFELVHYAGVVPYNISGWLEKNKDFLNETVVAIFQKSSNRLLANLFENYISTNTALQFGEKKRKKGASFQMVASLHKENLNKLMTKLKSTAPHFVRCINPNVNKTPGVMDPYLVLQQLRCNGVLEGITICREGFPHRLLYADFKQRYYILNPRVFPKSKFASNRKAAEELLDSLEIDHTQYRFGITKVLLKDGSLSKLEAMRDERLSKVFTLFQARVRGKLMQIKFQRILEERDALLLIQWNIRAFIAVKSWPWMRLFFEIKPLVRSAGMGKEGAGLKEECMQLQKALEKSESQREELKSKQVSLLQEKNDLLLQLQAERETLANVEEQCELLIKSKIQLEASVKALSARVEEEEEINSKLTARGQKLEDECSELKKEIDDLETLLAKSQKEKHATELKVKNLLEEVESLNEDVSKLHRAARAAQETHQQTLEDLRNEEEKVHTLSKAKLTLEQRVNELEGALEQESKARMNCEKEKCKVEGELKLNQESMDDLESRQLQLAEKLRRKELEMNQMRSKVENEKSLVAQLQKTVKEFQTQIQLLKEELEAERTTRAKVERERANLIRELEDMNERLEEAGGVSSAQLEITKKQETKFQKLRRDLEEATLHFEATSASLKKRHADSLAELESQVENLQQVKQTLEKDKSDLELEVNDLLIHVEQMTRAKANAEKLCSLYEERLKEANAKLDEVTQLANDVTAQKTKLRSENGELRKRLEEMEALINQLSREKSIFTLQIQDLKGQLAEETKSQSALAQAVKSAKRDCDLLREQYEEEQAAKAELLQALLKGNAEMVKWRTKYEDDTIQRAEDLEDAKKKLALRLQEAAEAMGVANARNASLERARLRLQLELGDTLSDLGQARSAAAALNQKQQHFDKSLDDWRRKHEESQAMLDAAKKEARALSIQLLELRHSYEEGTMSQEALRRENKHLKEEISNLTNQVREGKKNLSKMEKVKKQIEQEKNEVQMALEEAEGALERNESKVLRLQLELSDTKAELERKLSEKDEEIENFRKKQQCAIDSLQLSLDSEARCRIEATRLKRSMEGDLTEMELQLSCASRQASEATKSLGQLQTQVKDLQVQVDDSTCMNSELKEQVAVAERRNALLQAEVEELRSLQEQTERSRRLAEEELLEATEKINLFHAQNTSLLSQKKKLEVDVARMQKEAEEAMQGCQNAEEKAKKAATEVANMSEALKKEQDTNAHLERMRKNMEQTIKDLQERLDDAEQTAIVGNRKQIQKLESRVRELEAELESEVQRNSEAQRGAHRLERCLKELTHQVEEDKKNMSRMQTLMDNLQLKVQSYKQQIESAEAEASQYRSKYKKQQHELNEAKERAEIAESQVNKLKMKAKEFGKKVHEE", "length": 1600, "header": "tr|A0ABI0P5X4-1|A0ABI0P5X4_BOVIN Computationally mapped isoform of Myosin heavy chain 15 OS=Bos taurus OX=9913 GN=MYH15 PE=3 SV=1 CANONICAL=A0A3Q1LL07-1" }, "locus": { "chromosome": "1", "start_pos": 53238077, "end_pos": 53112786, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149347.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149347.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107238.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107238.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1404, "end_pos": 1406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1504, "end_pos": 1506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1515, "end_pos": 1517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1547, "end_pos": 1549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1713, "end_pos": 1715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1757, "end_pos": 1759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1853, "end_pos": 1855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" }, { "id": "PS51844", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51844" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin N-terminal SH3-like", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 79, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL07" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 771, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1404, "end_pos": 1406 }, { "start_pos": 1504, "end_pos": 1506 }, { "start_pos": 1515, "end_pos": 1517 }, { "start_pos": 1547, "end_pos": 1549 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 1713, "end_pos": 1715 }, { "start_pos": 1757, "end_pos": 1759 }, { "start_pos": 1853, "end_pos": 1855 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 671, "end_pos": 673 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LL13-1", "uniprot_ac": "A0A3Q1LL13", "uniprot_id": "A0A3Q1LL13_BOVIN", "mass": { "chemical_mass": 57441.0, "monoisotopic_mass": 57441.0 }, "refseq": { "ac": "XP_010815572", "name": "FERM domain-containing protein 5 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815572" }, "gene_names": [ { "name": "FRMD5", "type": "recommended", "evidence": [ { "id": "A0A3Q1LL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ] }, { "name": "FRMD5", "type": "synonym", "evidence": [ { "id": "XP_010815572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815572" } ] } ], "protein_names": [ { "name": "FERM domain-containing protein 5", "type": "recommended", "evidence": [ { "id": "A0A3Q1LL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13/entry#names_and_taxonomy" } ] }, { "name": "FERM domain-containing protein 5 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_010815572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815572" } ] } ], "function": [ { "annotation": "May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13#function" }, { "database": "UniProtKB", "id": "ARBA00054411", "url": "https://www.uniprot.org/uniprotkb/ARBA00054411#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FRMD5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13", "locus": { "chromosome": "21", "start_pos": 55494315, "end_pos": 55815997, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017216", "url": "https://www.ensembl.org/id/ENSBTAG00000017216" } ] } } ], "crossref": [ { "id": "A0A3Q1LL13", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LL13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017216", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017216", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13192", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13192", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17102", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17102", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "615161", "url": "https://www.ncbi.nlm.nih.gov/gene/615161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615161", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HFLQWNE", "url": "https://omabrowser.org/oma/group/HFLQWNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LL13", "url": "https://www.orthodb.org/?gene=A0A3Q1LL13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23280", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23280", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23280:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23280:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010815572", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815572", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T526", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T526", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T526-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T526-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB79", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB79-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSRLMSGSSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRASSHGDTFLPHARSSRADSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTAAKLEALGGELRALCQGHGRPEEEQAMVCLQNPLSGEPAH", "length": 508, "header": "tr|A0A3Q1LL13-1|A0A3Q1LL13_BOVIN Isoform 1 of FERM domain-containing protein 5 OS=Bos taurus OX=9913 GN=FRMD5 PE=4 SV=3 CANONICAL=A0A3Q1LL13-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LL13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13/entry", "sequence": { "sequence": "MLSRLMSGSSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRASSHGDTFLPHARSSRADSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTAAKLEALGGELRALCQGHGRPEEEQAMVCLQNPLSGEPAH", "length": 508, "header": "tr|A0A3Q1LL13-1|A0A3Q1LL13_BOVIN Isoform 1 of FERM domain-containing protein 5 OS=Bos taurus OX=9913 GN=FRMD5 PE=4 SV=3 CANONICAL=A0A3Q1LL13-1" }, "locus": { "chromosome": "21", "start_pos": 55815798, "end_pos": 55495033, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073093.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073093.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060434.3", "url": "https://www.ensembl.org/id/ENSBTAP00000060434.3" } ] } }, { "isoform_ac": "A0AAA9T526-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T526/entry", "sequence": { "sequence": "TEWTPTRVRNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRASSHGDTFLPHARSSRADSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTAAKLEALGGELRALCQGHGRPEEEQVNKFVLSVLRLLLVTMGLLFVLLLLLIILTESDLDIAFFRDIRQTPEFEQFHYQYFCPLRRWFACKIRSVVSLLIDT", "length": 336, "header": "tr|A0AAA9T526-1|A0A3Q1LL13_BOVIN Computationally mapped isoform of FERM domain-containing protein 5 OS=Bos taurus OX=9913 GN=FRMD5 PE=4 SV=1 CANONICAL=A0A3Q1LL13-1" }, "locus": { "chromosome": "21", "start_pos": 55518040, "end_pos": 55495026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088615.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088615.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093884.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093884.1" } ] } }, { "isoform_ac": "A0AAA9TB79-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB79/entry", "sequence": { "sequence": "MGKSLIKIHTRVRVQLRLTNHCLRPLSVRILRLGPRLQGRLLTAVPPRQGDQLEHLQGLESLRDSAHSTPVRASSHGDTFLPHARSSRADSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTAAKLEALGGELRALCQGHGRPEEEQVNKFVLSVLRLLLVTMGLLFVLLLLLIILTESDLDIAFFRDIRQTPEFEQFHYQYFCPLRRWFACKIRSVVSLLIDT", "length": 249, "header": "tr|A0AAA9TB79-1|A0A3Q1LL13_BOVIN Computationally mapped isoform of FERM domain-containing protein 5 OS=Bos taurus OX=9913 GN=FRMD5 PE=4 SV=1 CANONICAL=A0A3Q1LL13-1" }, "locus": { "chromosome": "21", "start_pos": 55498289, "end_pos": 55495026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122203.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122203.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094103.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094103.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 276, "start_aa": "Thr", "end_pos": 276, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr276", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 433, "start_aa": "Thr", "end_pos": 433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr433", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:615161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615161", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PU93-1", "protein_name": "FERM domain-containing protein 5", "gene_name": "FRMD5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLSRWMSGSSRNLEREYNCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQMRAQPPFTMCFRVKFYPTDPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLERKIAEIHKSELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKWNEVTKMKFEGKTFYLYVSQKEEKKIVLTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGLVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSASHGDAFVPHGRGGRADSSERVAIIADESYSPADSVLPTPVAEHSLELLLLSRQLNGAPCSIEEEKESEAGTPGTEPEEPRELRALCPGGGGPRAEQVNKFVLSVLRLLLVTVGLLFVLLLLLIVLTESDLDTAFFRDIRQTPEFEQFHYQYFCPLRRWFACKLRAVVALLTDT", "length": 568 }, "evidence": [ { "id": "A0A3Q1LL13", "url": "https://omabrowser.org/oma/group/A0A3Q1LL13/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1REH1-1", "protein_name": "FERM domain-containing protein 5", "gene_name": "frmd5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMLSRLMSGSVRNLEREYMCTVRLLDDTEYTCTIQRDAKGQYLFDLICHHLNLLEKDYFGIRYVDPDKQRHWLEFTKSISKQMKSQPPFTMCLRVKFYPPDPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAAMLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLERRIAEIHKTELIGQTPETSELKFLQKAQMLETYGVDPHPCKDVSGNPAFLAFTPFGFVVLQGNKRVHFLKWNEVTKLKFEGKTFHIYANQKEDKKIILTYFAPTPEACKHLWKCGVENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMEQSAKIKREPPEIHRAGLVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSVSHGDSFMPRSRSQMTDSGDRTAIISDESYSPSDSVLPTPVAEHSLELAVSRQINGAPCSIEEEKESEAGTPSVGDVAEFGADSRAAGPMQIAGREAPLSEAEQVNKFVLSVLRLLLVTIGLLFVLLLLLIVLTESDLDIAFLRDIRQTPEFEQFHYEYFCPLRRWFACKLRWVGGLLINK", "length": 576 }, "evidence": [ { "id": "A0A3Q1LL13", "url": "https://omabrowser.org/oma/group/A0A3Q1LL13/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P5H6-1", "protein_name": "FERM domain-containing protein 5", "gene_name": "Frmd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSRLMSGSSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLEKKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSSSHGDTFLPHVRSSRADSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEAEALGGELRALCQGHGGSEQEQRVHLKGPQLQQQQWKGWGKSVPLD", "length": 517 }, "evidence": [ { "id": "A0A3Q1LL13", "url": "https://omabrowser.org/oma/group/A0A3Q1LL13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z6J6-1", "protein_name": "FERM domain-containing protein 5", "gene_name": "FRMD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSRLMSGSSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPDKQRHWLEFTKSVVKQLRSQPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLAAYILQAEIGDYDSGKHPEGYSSKFQFFPKHSEKLERKIAEIHKTELSGQTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKWNEVTKLKFEGKTFYLYVSQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSTSHGDTFLPHVRSSRTDSNERVAVIADEAYSPADSVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEVEALGGELRALCQGHSGPEEEQVNKFVLSVLRLLLVTMGLLFVLLLLLIILTESDLDIAFFRDIRQTPEFEQFHYQYFCPLRRWFACKIRSVVSLLIDT", "length": 570 }, "evidence": [ { "id": "A0A3Q1LL13", "url": "https://omabrowser.org/oma/group/A0A3Q1LL13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "pmid": "" }, { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cell adhesion", "id": "GO:0045785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "pmid": "" }, { "name": "negative regulation of cell motility", "id": "GO:2000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000146", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LL13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 508, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LL13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LL13" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL13" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 298, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 276, 433 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LL18-1", "uniprot_ac": "A0A3Q1LL18", "uniprot_id": "A0A3Q1LL18_BOVIN", "mass": { "chemical_mass": 118416.0, "monoisotopic_mass": 118416.0 }, "refseq": {}, "gene_names": [ { "name": "EMILIN2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18" } ] } ], "protein_names": [ { "name": "EMILIN-2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18/entry#names_and_taxonomy" } ] }, { "name": "Elastin microfibril interface-located protein 2", "type": "synonym", "evidence": [ { "id": "A0A3Q1LL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL18", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EMILIN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18", "locus": { "chromosome": "24", "start_pos": 37135870, "end_pos": 37076574, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003880", "url": "https://www.ensembl.org/id/ENSBTAG00000003880" } ] } } ], "crossref": [ { "id": "A0A3Q1LL18", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LL18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003880", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003880", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LL18", "url": "https://www.orthodb.org/?gene=A0A3Q1LL18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BIP4", "url": "https://www.orthodb.org/?gene=E1BIP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LL18", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL18-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVZ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIP4", "url": "https://www.uniprot.org/uniprotkb/E1BIP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIP4-1", "url": "https://www.uniprot.org/uniprotkb/E1BIP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWPPTWPRPRPRPRAPWRWALALLALGGAGLCHASPQPGHPARPSARNKNWCAYIVNKNVSCSVLEGSETFIQAQYNCGWNQKPCPSALMYRVNVRPRYVTRYKTVTQLEWRCCPGFRGGNCQEGPRDPGRMPRPMPARPRNSMKKPTDNEPSRVSEPKNTVSPTPAADPSQTRDPKQGPQELQEKKIQVLEEKVLRLTRTVLDLQSSVAGVSENLKHAVQDDASKMLASWLSNLHPRPTPISAVGGEPETVQPPGILSNKESGMKDIKSELAEVKDALKTKSDKLEELDGKVKGYEGQLRQLQEAAQGPTVTMTTSELFQAYVDSKIDALREELMEGMDRKLADLKNSCEYKLIGFQQHCDDYGSSYLGVIELIGEKEAKLRKEISDLQARVQDPPAHANCCDGTKPGDLGPQIKMLDQKIERVSEATRMLNARLDNEFDRLEAPEPDVDFDARWHELDARINVTERNAEEHCFYIEETLRGTISGEVDGLRQLLDQKIQSLEERLGSALLEMVNGSEMVPAPPVAAPPTVSGAGPPQVMMELKRLKDQVRVVEDMCLQNFRGEPRGMEDTLRNGGEMVSLLRSLNDTMQGKFQDTERSIQRLQQDFSFLYSWLNHTDDHLRRLQNELSGGRGGKKAAGGGWSKVGEPGRTEAPLPSPQAPPAHCCDQLEGRWQRLQDLVLSELDTCKEKTHGVQREVSVVEDRVSHVEKTCSKLDSISGSLQKIKEGLNKHVNSLWSCIRQMNGTLRTHSREISGLKNSVQQFYSHVFQISADLQDLIRFQPSAKDPSETPQPPPRGKAPEDVGKPSSPAEAPTELSTPVLTPLLPPSTPSPPRDPGQKPVLPKRRPPPLRPGWTGLPFLPGSTGVIMETGEAGPPGRMGVSGRGLPRGVDGQTGQRPIPSAEGYAGAPGYPKSPPAASPGAPVPSLVSFSAGLTRKPFPSDAGVVLFNKVLVNDGDVYDPSTGVFTAPYDGRYLITATLTPERDAYVEAVLSVANASVAQLHTAGYRREFLEYHRPQGAPHTCGGPGAFHLIVHLKAGDGVNIVVTGGRLAHTDFDEMYSTFSGVFLYPFLSHL", "length": 1077, "header": "tr|A0A3Q1LL18-1|A0A3Q1LL18_BOVIN Isoform 1 of EMILIN-2 OS=Bos taurus OX=9913 GN=EMILIN2 PE=4 SV=2 CANONICAL=A0A3Q1LL18-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LL18-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL18/entry", "sequence": { "sequence": "MWPPTWPRPRPRPRAPWRWALALLALGGAGLCHASPQPGHPARPSARNKNWCAYIVNKNVSCSVLEGSETFIQAQYNCGWNQKPCPSALMYRVNVRPRYVTRYKTVTQLEWRCCPGFRGGNCQEGPRDPGRMPRPMPARPRNSMKKPTDNEPSRVSEPKNTVSPTPAADPSQTRDPKQGPQELQEKKIQVLEEKVLRLTRTVLDLQSSVAGVSENLKHAVQDDASKMLASWLSNLHPRPTPISAVGGEPETVQPPGILSNKESGMKDIKSELAEVKDALKTKSDKLEELDGKVKGYEGQLRQLQEAAQGPTVTMTTSELFQAYVDSKIDALREELMEGMDRKLADLKNSCEYKLIGFQQHCDDYGSSYLGVIELIGEKEAKLRKEISDLQARVQDPPAHANCCDGTKPGDLGPQIKMLDQKIERVSEATRMLNARLDNEFDRLEAPEPDVDFDARWHELDARINVTERNAEEHCFYIEETLRGTISGEVDGLRQLLDQKIQSLEERLGSALLEMVNGSEMVPAPPVAAPPTVSGAGPPQVMMELKRLKDQVRVVEDMCLQNFRGEPRGMEDTLRNGGEMVSLLRSLNDTMQGKFQDTERSIQRLQQDFSFLYSWLNHTDDHLRRLQNELSGGRGGKKAAGGGWSKVGEPGRTEAPLPSPQAPPAHCCDQLEGRWQRLQDLVLSELDTCKEKTHGVQREVSVVEDRVSHVEKTCSKLDSISGSLQKIKEGLNKHVNSLWSCIRQMNGTLRTHSREISGLKNSVQQFYSHVFQISADLQDLIRFQPSAKDPSETPQPPPRGKAPEDVGKPSSPAEAPTELSTPVLTPLLPPSTPSPPRDPGQKPVLPKRRPPPLRPGWTGLPFLPGSTGVIMETGEAGPPGRMGVSGRGLPRGVDGQTGQRPIPSAEGYAGAPGYPKSPPAASPGAPVPSLVSFSAGLTRKPFPSDAGVVLFNKVLVNDGDVYDPSTGVFTAPYDGRYLITATLTPERDAYVEAVLSVANASVAQLHTAGYRREFLEYHRPQGAPHTCGGPGAFHLIVHLKAGDGVNIVVTGGRLAHTDFDEMYSTFSGVFLYPFLSHL", "length": 1077, "header": "tr|A0A3Q1LL18-1|A0A3Q1LL18_BOVIN Isoform 1 of EMILIN-2 OS=Bos taurus OX=9913 GN=EMILIN2 PE=4 SV=2 CANONICAL=A0A3Q1LL18-1" }, "locus": { "chromosome": "24", "start_pos": 37135193, "end_pos": 37076794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080161.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080161.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060444.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060444.2" } ] } }, { "isoform_ac": "A0AAA9TVZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ5/entry", "sequence": { "sequence": 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"evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019983", "url": "https://www.ensembl.org/id/ENSBTAG00000019983" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019983", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019983", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100140419", "url": "https://www.ncbi.nlm.nih.gov/gene/100140419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100140419", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WELKQSE", "url": "https://omabrowser.org/oma/group/WELKQSE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LL22", "url": "https://www.orthodb.org/?gene=A0A3Q1LL22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N2W4", "url": "https://www.orthodb.org/?gene=F1N2W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13578", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13578", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13578:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13578:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13922", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13922", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005213137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213137", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL22", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL22-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2W4", "url": "https://www.uniprot.org/uniprotkb/F1N2W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2W4-1", "url": "https://www.uniprot.org/uniprotkb/F1N2W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEISGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSSDGGSNKEGKKSRWKRKVSSRLSQPSSPHSGCPSPTIPAGKVISSSQKHSKKALKQALKQQQQKKQQQQQCRPSMSISSNQHLSLKTVKASSDPVPAKPAIWEGKQSDGQSSSPQNSNSSFSSSSVKVENHLLGLGKKSFQRSDRLHTRQMKRTKCAEIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPNDPKVKKTPAEQPKSTLPSEASPVSVVPVIPQLESKEEVLQMPSPVRKEEHESQDKTQPHSTEPLLSPATNTNELSSIPPIKCPKDEALVEQKPVASAEQESEKKNHLTTASNYNKNESQEALVTSLSKPKSPGVETTVMKPTVEASPQETTMKEPPSTLADHSPESLKRKSSLTQEEAPTSWEKRPRVTEHRQHQQPFQVSPQPFLSRGDRFQVRRVPPLKIPVSRISPMPFPTSQVSPRARFPISITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPGPGGGQGPGEGGERRTARGGDPDSDKVSEPSKGPALELAGTGSRGGTRELLPAGPDTQPQSETRTAGQPQPLSGPGAQLQQTPSVPPASAVGGACAGVPSPAHIHALPPALGKLSNEKLNPPRVTGTVASLSQPQGPSNGRQEKAPPAPADPALIMGASPVHFAAAGAVEPKAGSSKNAPNPPASAEISASASVDTTASPLTSLLTTATLEKLPVPQVSVTTTPTGSAPSLSTLPAASSLKTPGTSSHMNGPISRPSSSIPANNPLVTQLLQGKDVPMEQILPKPLTKVEMKTVPLTTKEEKGVGALIGTSVTENSTREEVHERQSHPAAQHLGKTLQSKQLPQVPRPLQLFSGKDLRDSGIDTHQYQEGLSKATQDQILQTLSQRVRRQNILSFVQPSQFNFTHSGFPLEDISTSQRFMLGFAGRRTSKPAMAGHYLLNISTYGRGTESFRRTHSVNPEDRFCLSSPTEALKMGYTDCKNAAGDSSSGKEDDTDEESTGDEQESVPVKEEPQASQSSGKCDASLGPHSRETLSTSDCSAKKNVKAETPVPEQTPLSKENYLFTRGQTFDEKTLARDFIQAAQKQMAHAVRGKTMRSSPELFNSTSLPLPADSPTHQSLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSSVPGMPDCSQVSSNVGDVMSFSVTVTAIPASQAVNAGSRGQTIPVQAFPEESSVEDTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "length": 1449, "header": "tr|A0A3Q1LL22-1|A0A3Q1LL22_BOVIN Isoform 1 of ASXL transcriptional regulator 2 OS=Bos taurus OX=9913 GN=ASXL2 PE=3 SV=1 CANONICAL=A0A3Q1LL22-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LL22-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL22/entry", "sequence": { "sequence": "MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEISGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSSDGGSNKEGKKSRWKRKVSSRLSQPSSPHSGCPSPTIPAGKVISSSQKHSKKALKQALKQQQQKKQQQQQCRPSMSISSNQHLSLKTVKASSDPVPAKPAIWEGKQSDGQSSSPQNSNSSFSSSSVKVENHLLGLGKKSFQRSDRLHTRQMKRTKCAEIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPNDPKVKKTPAEQPKSTLPSEASPVSVVPVIPQLESKEEVLQMPSPVRKEEHESQDKTQPHSTEPLLSPATNTNELSSIPPIKCPKDEALVEQKPVASAEQESEKKNHLTTASNYNKNESQEALVTSLSKPKSPGVETTVMKPTVEASPQETTMKEPPSTLADHSPESLKRKSSLTQEEAPTSWEKRPRVTEHRQHQQPFQVSPQPFLSRGDRFQVRRVPPLKIPVSRISPMPFPTSQVSPRARFPISITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPGPGGGQGPGEGGERRTARGGDPDSDKVSEPSKGPALELAGTGSRGGTRELLPAGPDTQPQSETRTAGQPQPLSGPGAQLQQTPSVPPASAVGGACAGVPSPAHIHALPPALGKLSNEKLNPPRVTGTVASLSQPQGPSNGRQEKAPPAPADPALIMGASPVHFAAAGAVEPKAGSSKNAPNPPASAEISASASVDTTASPLTSLLTTATLEKLPVPQVSVTTTPTGSAPSLSTLPAASSLKTPGTSSHMNGPISRPSSSIPANNPLVTQLLQGKDVPMEQILPKPLTKVEMKTVPLTTKEEKGVGALIGTSVTENSTREEVHERQSHPAAQHLGKTLQSKQLPQVPRPLQLFSGKDLRDSGIDTHQYQEGLSKATQDQILQTLSQRVRRQNILSFVQPSQFNFTHSGFPLEDISTSQRFMLGFAGRRTSKPAMAGHYLLNISTYGRGTESFRRTHSVNPEDRFCLSSPTEALKMGYTDCKNAAGDSSSGKEDDTDEESTGDEQESVPVKEEPQASQSSGKCDASLGPHSRETLSTSDCSAKKNVKAETPVPEQTPLSKENYLFTRGQTFDEKTLARDFIQAAQKQMAHAVRGKTMRSSPELFNSTSLPLPADSPTHQSLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSSVPGMPDCSQVSSNVGDVMSFSVTVTAIPASQAVNAGSRGQTIPVQAFPEESSVEDTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "length": 1449, "header": "tr|A0A3Q1LL22-1|A0A3Q1LL22_BOVIN Isoform 1 of ASXL transcriptional regulator 2 OS=Bos taurus OX=9913 GN=ASXL2 PE=3 SV=1 CANONICAL=A0A3Q1LL22-1" }, "locus": { "chromosome": "11", "start_pos": 73647161, "end_pos": 73542167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069775.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069775.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057462.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057462.1" } ] } }, { "isoform_ac": "F1N2W4-1", "url": "https://www.uniprot.org/uniprotkb/F1N2W4/entry", "sequence": { "sequence": "MFREELYGIPSQVSSRLSQPSSPHSGCPSPTIPAGKVISSSQKHSKKALKQALKQQQQKKQQQQQCRPSMSISSNQHLSLKTVKASSDPVPAKPAIWEGKQSDGQSSSPQNSNSSFSSSSVKVENHLLGLGKKSFQRSDRLHTRQMKRTKCAEIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPNDPKVKKTPAEQPKSTLPSEASPVSVVPVIPQLESKEEVLQMPSPVRKEEHESQDKTQPHSTEPLLSPATNTNELSSIPPIKCPKDEALVEQKPVASAEQESEKKNHLTTASNYNKNESQEALVTSLSKPKSPGVETTVMKPTVEASPQETTMKEPPSTLADHSPESLKRKSSLTQEEAPTSWEKRPRVTEHRQHQQPFQVSPQPFLSRGDRFQVRRVPPLKIPVSRISPMPFPTSQVSPRARFPISITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPGPGGGQGPGEGGERRTARGGDPDSDKVSEPSKGPALELAGTGSRGGTRELLPAGPDTQPQSETRTAGQPQPLSGPGAQLQQTPSVPPASAVGGACAGVPSPAHIHALPPALGKLSNEKLNPPRVTGTVASLSQPQGPSNGRQEKAPPAPADPALIMGASPVHFAAAGAVEPKAGSSKNAPNPPASAEISASASVDTTASPLTSLLTTATLEKLPVPQVSVTTTPTGSAPSLSTLPAASSLKTPGTSSHMNGPISRPSSSIPANNPLVTQLLQGKDVPMEQILPKPLTKVEMKTVPLTTKEEKGVGALIGTSVTENSTREEVHERQSHPAAQHLGKTLQSKQLPQVPRPLQLFSGKDLRDSGIDTHQYQEGLSKATQDQILQTLSQRVRRQNILSFVQPSQFNFTHSGFPLEDISTSQRFMLGFAGRRTSKPAMAGHYLLNISTYGRGTESFRRTHSVNPEDRFCLSSPTEALKMGYTDCKNAAGDSSSGKEDDTDEESTGDEQESVPVKEEPQASQSSGKCDASLGPHSRETLSTSDCSAKKNVKAETPVPEQTPLSKENYLFTRGQTFDEKTLARDFIQAAQKQMAHAVRGKTMRSSPELFNSTSLPLPADSPTHQSLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSSVPGMPDCSQVSSNVGDVMSFSVTVTAIPASQAVNAGSRGQTIPVQAFPEESSVEDTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "length": 1328, "header": "tr|F1N2W4-1|A0A3Q1LL22_BOVIN Computationally mapped isoform of ASXL transcriptional regulator 2 OS=Bos taurus OX=9913 GN=ASXL2 PE=3 SV=2 CANONICAL=A0A3Q1LL22-1" }, "locus": { "chromosome": "11", "start_pos": 73647161, "end_pos": 73618151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026618.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026618.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026618.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026618.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100140419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140419", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689603", "resource": "Reactome", "description": "UCH proteinases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZR15-1", "protein_name": "ASXL transcriptional regulator 2", "gene_name": "Asxl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEIRSGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSDGGSNKEGRKSRWKRKVSSRLSQPSSPQSSCPSPTIPASKVISPSQKHSKKALKQALKQQQQKKQQQQQQQQCRPSMSISNQHLSLKTVKTASDSVPAKPALWEGKQSDGQSSSPQNSNSSFSSSVKVESSLLGLGKKSLQRSDRLHTRQMKRTKCADIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVELWKEQFFESYYGQSSGLSLEDSQKLTASPSDPKANKSPAEQPKSILPSEASPVSTIPVFPQSECKEEAVQIPSPFKKESQDEARPISQSPETVLALASNTNELITVKPIKSPKDEGLLEQKPVASAEQESEKENHVTTSSSNESENQEALAISASKPKNAGFEKPTTTKPAGASPLGPDMQVPPAPVSDHIPESLKRKAALTQEEATSSWEKRPRITENRQHQQPFQASPQPFLNRGDRAQVRKVPPLKIPVSRISPMLFSTSQVSPRARFPVSITSPYRTGARTLADIKAKAQLVKAQKAAAAAAAAAAAAASVGGTIPGPGPGGGRSPREGGERKTAGGGSAGSDPVSTNGKGPALELAGTGSRGGTRELLPCDPQPETNTPGQAQPPGVSGAQLQQTSSVPAGLAASGTCTSVPLPAHIEMSNREKPNPHRATATAASPCHSQEPRSCRLERALSPTGPPLISGASPVCFVADGTVEPKAGSNKNAPKPSALTKTTASAPLDMTSSPVTSLLTTASLEKLPAPQISGAATSTGSAPSSSTLPVASSLKTPGTSANMNGPVSRPSSSIPANNPLVTQLLQGKDVPLEQILPKPLTKIEMKTVPLHTKEERGGIGVFPGTSVVEGSREDVSGRQAHLAIQQLGKPLQSKQLSQAPRPVCPAKDRKDPCIDTHQYQEGLSKTTQGQLFQTLIQRAQRQSVLSFVPPTQFNFAHSGFHLEDISTSQKFMLGFAGRRTSKPAMAGHYLLNISTYGRGTDSVKRTHSVNPEERFCLSSPTEALRVGHADCKNTTGESSSSKEEESDEDSVGDEQESVSVKEEPWAPHSGEAPSTNDCLASKSGKTEVPVNEQTTLGKENYILSRGQTFDEKTLARDFIQATHKQMAHAVRGKTVCSSPELFNSTALSLPADSPTHQPLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSAIPGSQVSSNVGDVMSFSVTVTTIPASQAMNPSSHGQTIPVQTFPDENSIEDTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "length": 1418 }, "evidence": [ { "id": "A0A3Q1LL22", "url": "https://omabrowser.org/oma/group/A0A3Q1LL22/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5ZM88-1", "protein_name": "Putative Polycomb group protein ASXL2", "gene_name": "ASXL2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MREKGRRKKGRTWAEAARTVLEKYPNTPMSHKEILQVIQKEGLKEIRSGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGLKELSDGSEESSDAQSDSQSSENSSSSSSSDGCTNKDGRKSRWKRKVSSRLSQTSSPQTSCQSPSIQTGKVISSSQKHSKKALKQALKQQQQKQQQQQCRAGMPVSSNQHTLLKAVKAASASTPTKPAWIGKQSDGHSNSSQNSTFSSSASVKLDNSLPGLGKKPFQRSDRLHARQLKRTKCAEIDVETPDSILVNTNLRALINKHTFSVLPTECQQRLLLLLPEVDRQVGADGLMKLSGSALNNEFFTSAAQGWKERLSEGEFTPEMQLRIRQEIEKEKKVELWKEHFFESYYGQSSGLSPEESERLTANTSADDGEAEKPAAEQPKCMQVKEEITSPSESKAQVVQEAPAVKKGEERRVEERREEMQPKAAKPAEASVSPAGCAVKPSNPQIQERIQGEPIQENPQPAVSQKLEEERKHTASKEVKEAVRAPVLAPSKPKSPEAGEAAAKVTSPVVVPPTPEKKPPVNEEMEVSVEGHKRKSESSEEALTTPGKKPRIAEKCQQQQPAFRSQTQSFPAAGPPVPRVPPLKIPVSRISPMPFPAGQVSPRVRFPASLISPARTGARTLADIKAKAQQVRAQRAAAAAAAAAASSGGAVPGPGPGGGPAGGGGTGNAATSGAGETGTRGNALELAGTGSGGSSRRFLPRCPGTHSPMETQEQPATPSLSRAQLQQTSVLQSRSAAGNTGTNCSSPAVSAIEQISGIKQSPPNVAINQVSGSSCAGGCDKQEKAPSAPAGLGQACGASTVRDGTTCVTVSSADSNANITRVAPAALGGTSSDVPKGTSPSPLMPSLTPTSSEAQAGGAVVSAPSAPCSNTLSAAPSLKTHPSSSGALPKANSSIPANNPLVTQLLQGKSVPLEQILPKPLTKAEMKTVPLASNEEKGAAVPGVAGSGAGAEGGERQSALSPQQLGKIFCQSRPLPHIPRTFVLPAGKEPGADQHPEALSKTTQEQILQTLIKRVQRQNLLPVLQPSQVNVAHSGFQLENSSTSQRFVLGFMGRRTSKPAMSGHYLLNISTYGRGSESLRRGFSLNPETRSCLNSPAGGPKAECGECEEMPDHGSSSEEEDADNESTGDEHEHVSVKEEPQASQVAAPCEKEQVSHGANSSDYGILAKKGVKTEAAVSQQAAGSRENSQALDGTALARDFIQAAQEQTVHAVKGKTHSSPELFSSSTPSSDSAQLQLPQLSHPHPPKLGGDAAAAQLIGPSYSGTINVSTSPDVNQGSLMSGLSECNQLSSSMGNVMSFSVTVTTIPTSQAMNSGNHSQTIPVQAFAEDSSMEDSPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "length": 1412 }, "evidence": [ { "id": "A0A3Q1LL22", "url": "https://omabrowser.org/oma/group/A0A3Q1LL22/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q76L83-1", "protein_name": "Putative Polycomb group protein ASXL2", "gene_name": "ASXL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEIRSGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSSDGGSNKEGKKSRWKRKVSSSSPQSGCPSPTIPAGKVISPSQKHSKKALKQALKQQQQKKQQQQCRPSISISSNQHLSLKTVKAASDSVPAKPATWEGKQSDGQTGSPQNSNSSFSSSVKVENTLLGLGKKSFQRSERLHTRQMKRTKCADIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPSDPKVKKTPAEQPKSMPVSEASLIRIVPVVSQSECKEEALQMSSPGRKEECESQGEVQPNFSTSSEPLLSSALNTHELSSILPIKCPKDEDLLEQKPVTSAEQESEKNHLTTASNYNKSESQESLVTSPSKPKSPGVEKPIVKPTAGAGPQETNMKEPLATLVDQSPESLKRKSSLTQEEAPVSWEKRPRVTENRQHQQPFQVSPQPFLNRGDRIQVRKVPPLKIPVSRISPMPFHPSQVSPRARFPVSITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPGPGGGQGPGEGGEGQTARGGSPGSDRVSETGKGPTLELAGTGSRGGTRELLPCGPETQPQSETKTTPSQAQPHSVSGAQLQQTPPVPPTPAVSGACTSVPSPAHIEKLDNEKLNPTRATATVASVSHPQGPSSCRQEKAPSPTGPALISGASPVHCAADGTVELKAGPSKNIPNPSASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQVSATTAPAGSAPPSSTLPAASSLKTPGTSLNMNGPTLRPTSSIPANNPLVTQLLQGKDVPMEQILPKPLTKVEMKTVPLTAKEERGMGALIATNTTENSTREEVNERQSHPATQQQLGKTLQSKQLPQVPRPLQLFSAKELRDSSIDTHQYHEGLSKATQDQILQTLIQRVRRQNLLSVVPPSQFNFAHSGFQLEDISTSQRFMLGFAGRRTSKPAMAGHYLLNISTYGRGSESFRRTHSVNPEDRFCLSSPTEALKMGYTDCKNATGESSSSKEDDTDEESTGDEQESVTVKEEPQVSQSAGKGDTSSGPHSRETLSTSDCLASKNVKAEIPLNEQTTLSKENYLFTRGQTFDEKTLARDLIQAAQKQMAHAVRGKAIRSSPELFSSTVLPLPADSPTHQPLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSAVPGSQVSSNVGDVMSFSVTVTTIPASQAMNPSSHGQTIPVQAFSEENSIEGTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "length": 1435 }, "evidence": [ { "id": "A0A3Q1LL22", "url": "https://omabrowser.org/oma/group/A0A3Q1LL22/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZ32-1", "protein_name": "Putative Polycomb group protein ASXL2", "gene_name": "Asxl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376864" }, "gene_names": [ { "name": "OR5B141", "type": "recommended", "evidence": [ { "id": "A0A3Q1LL50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL50" } ] }, { "name": "OR5B141", "type": "synonym", "evidence": [ { "id": "NP_001376864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376864" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LL50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL50/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5B2", "type": "synonym", "evidence": [ { "id": "NP_001376864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376864" } ] }, { "name": "olfactory receptor family 5 subfamily B member 141", "type": "synonym", "evidence": [ { "id": "NP_001376864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376864" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376864", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376864" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL50#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL50" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5B141", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL50", "locus": { "chromosome": "15", "start_pos": 81629911, "end_pos": 81630849, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000051853", "url": "https://www.ensembl.org/id/ENSBTAG00000051853" } ] } } ], "crossref": [ { "id": "A0A3Q1LL50", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LL50", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513948", "url": "https://www.ncbi.nlm.nih.gov/gene/513948", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513948", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513948", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDFFLVG", "url": "https://omabrowser.org/oma/group/MDFFLVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LL50", "url": "https://www.orthodb.org/?gene=A0A3Q1LL50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376864", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL50", 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519816", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519816", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCYRFAF", "url": "https://omabrowser.org/oma/group/RCYRFAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LL63", "url": "https://www.orthodb.org/?gene=A0A3Q1LL63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MS62", "url": "https://www.orthodb.org/?gene=F1MS62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12215:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12215:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-199220", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-199220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12068", "url": "https://www.rhea-db.org/rhea/12068", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46564", "url": "https://www.rhea-db.org/rhea/46564", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LL63", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LL63-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MS62", "url": "https://www.uniprot.org/uniprotkb/F1MS62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MS62-1", "url": "https://www.uniprot.org/uniprotkb/F1MS62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLAWRLCVLPAMEGVRWAFPCGTWLPSRAEWLLAVRSIQPEEKERIGQFVFARDAKAALAGRLMIRKLVAEKLNIPWNNIRLQRTAKGKPVLAKDSLNPYPNFNFNISHQGDYAVLAAESELQVGIDIMKTSFPGRGSIPEFFHIMKRKFTDKEWETIRSFKDEWTQLDMFYRNWALKESFIKAIGVGLGFELQRLEFDISPLNLDIGQVYKETRLFLDGEEEKEWAFEESKIDEHHFVAVALRKPNGSRHQNVTSQDDSKATQRQFTILTFNDLISSAVPMTPEDPSFWDCFCFTEEISIRNGTKS", "length": 309, "header": "tr|A0A3Q1LL63-1|A0A3Q1LL63_BOVIN Isoform 1 of L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Bos taurus OX=9913 GN=AASDHPPT PE=3 SV=1 CANONICAL=A0A3Q1LL63-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LL63-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63/entry", "sequence": { "sequence": "MVLLAWRLCVLPAMEGVRWAFPCGTWLPSRAEWLLAVRSIQPEEKERIGQFVFARDAKAALAGRLMIRKLVAEKLNIPWNNIRLQRTAKGKPVLAKDSLNPYPNFNFNISHQGDYAVLAAESELQVGIDIMKTSFPGRGSIPEFFHIMKRKFTDKEWETIRSFKDEWTQLDMFYRNWALKESFIKAIGVGLGFELQRLEFDISPLNLDIGQVYKETRLFLDGEEEKEWAFEESKIDEHHFVAVALRKPNGSRHQNVTSQDDSKATQRQFTILTFNDLISSAVPMTPEDPSFWDCFCFTEEISIRNGTKS", "length": 309, "header": "tr|A0A3Q1LL63-1|A0A3Q1LL63_BOVIN Isoform 1 of L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Bos taurus OX=9913 GN=AASDHPPT PE=3 SV=1 CANONICAL=A0A3Q1LL63-1" }, "locus": { "chromosome": "15", "start_pos": 1594159, "end_pos": 1570723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067243.1", "url": "https://www.ensembl.org/id/ENSBTAT00000067243.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057509.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057509.1" } ] } }, { "isoform_ac": "F1MS62-1", "url": "https://www.uniprot.org/uniprotkb/F1MS62/entry", "sequence": { "sequence": "AKAQSNYEGLLKLFNLVPLLSEPGPVIRTEPPAPQQQNPHFSPQGSGPGLANAETAPGSLDGLCTAPWLARSLGLRRGPCRSRRSEAGLGAGAGIGPEGPRGAQTSGVGCWGRQPGALETTPEAPRGALCHGSPLAPAQDERHGRPRPESPRLCGRRGRPWPGNEAGPRRSPGAPRSPTCTAVSEVSSPASPLPRPGCDWLPPLSRCLFFKSERPPVRAAPPSRPSRPRGPAPRAVTRCRRTQRTQSAEQGPGFRGGGGRADDAQRGPQAGRLMIRKLVAEKLNIPWNNIRLQRTAKGKPVLAKDSLNPYPNFNFNISHQGDYAVLAAESELQVGIDIMKTSFPGRGSIPEFFHIMKRKFTDKEWETIRSFKDEWTQLDMFYRNWALKESFIKAIGVGLGFELQRLEFDISPLNLDIGQVYKETRLFLDGEEEKEWAFEESKIDEHHFVAVALRKPNGSRHQNVTSQDDSKATQRQFTILTFNDLISSAVPMTPEDPSFWDCFCFTEEISIRNGTKS", "length": 517, "header": "tr|F1MS62-1|F1MS62_BOVIN Computationally mapped isoform of L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Bos taurus OX=9913 GN=AASDHPPT PE=3 SV=2 CANONICAL=A0A3Q1LL63-1" }, "locus": { "chromosome": "15", "start_pos": 1595200, "end_pos": 1570723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000040234.5", "url": "https://www.ensembl.org/id/ENSBTAT00000040234.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040011.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040011.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:519816", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519816", "resource": "KEGG Pathway" }, { "id": "R-BTA-199220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-199220", "resource": "Reactome", "description": "Vitamin B5 (pantothenate) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XPN9-1", "protein_name": "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "gene_name": "AASDHPPT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGGVRWAFPCAAWRPRREEWLLAARLVQPEEKERIGSFVYARDAKAALAGRLLMRKLIAEKLCIPWNEIHLQRTSKGKPFLANSIFSVYSNYNFNVSHQGDYAVLAAEPELQVGIDVMKTDLPGSSSIPNFFRIMKRQFTETEWHVIRSMNNEWMQLDMFHRHWALKESFLKAIGVGIGFNLQRIEFNVSPLQMEIGKVYSETQMLLDGEKEEEWTFETDLNPRHVILMSLRNEETRLDGYHHVAVALGKQEGFGQQHTDVCSMQPHRPQFTLLTFEDLVAPGIPITPEDSAYWDNFCSKQESPVKQSSNSR", "length": 312 }, "evidence": [ { "id": "A0A3Q1LL63", "url": "https://omabrowser.org/oma/group/A0A3Q1LL63/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL63", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ], "pmid": "" }, { "name": "holo-[acyl-carrier-protein] synthase activity", "id": "GO:0008897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008897", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL63", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL63", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lysine biosynthetic process via aminoadipic acid", "id": "GO:0019878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019878", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LL63", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12068", "name": "", "equation": "apo-[ACP] + CoA = holo-[ACP] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LL63-1" ], "evidence": [ { "id": "12068", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12068" } ] }, { "id": "46564", "name": "", "equation": "apo-[ACP] + acetyl-CoA = acetyl-[ACP] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LL63-1" ], "evidence": [ { "id": "46564", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46564" } ] }, { "id": "R-BTA-199202", "name": "Phosphopantetheine conjugation of the ACP domain of FAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-BTA-199233" ], "output_participant_list": [ "R-BTA-54659" ], "enzyme_list": [ "A0A3Q1LL63-1", "A0ABI0NT64-1" ], "evidence": [ { "id": "R-BTA-199202", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-199202" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-199233", "participant_name": "FASN [cytosol]", "crossref": [ { "id": "F1N647", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000015980", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000021260", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000021260", "database": "ENSEMBL", "url": "" }, { "id": "28871", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-54659", "participant_name": "phospho-FASN [cytosol]", "crossref": [ { "id": "ENSBTAG00000015980", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000021260", "database": "ENSEMBL", "url": "" }, { "id": "28871", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000021260", "database": "ENSEMBL", "url": "" }, { "id": "F1N647", "database": "UniProt", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LL63", "gene_name": "AASDHPPT", "activity": [ { "ec_number": "2.7.8.7", "activity": "apo-[ACP] + CoA = holo-[ACP] + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "A0A3Q1LL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ] }, { "ec_number": "2.7.8.7", "activity": "", "evidence": [ { "id": "A0A3Q1LL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ] } ] }, { "uniprot_ac": "A0ABI0NT64", "gene_name": "FASN", "activity": [ { "ec_number": "1.1.1.100", "activity": "a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "1.3.1.39", "activity": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.38", "activity": "holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.85", "activity": "acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "4.2.1.59", "activity": "a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "3.1.2.14", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.38", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.41", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "1.1.1.100", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.85", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "1.3.1.39", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "4.2.1.59", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.39", "activity": "", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LL63-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LL63-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LL63" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" }, { "id": "PF01648", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01648" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "4'-phosphopantetheinyl transferase", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 242, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" }, { "id": "PF22624", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22624" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "4'-phosphopantetheinyl transferase N-terminal", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 122, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.8.7", "ec_name": "apo-[ACP] + CoA = holo-[ACP] + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "2.7.8.7", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.8.7" }, { "id": "2.7.8.7", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.8.7" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 305, "end_pos": 307 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LL79", "url": "https://www.orthodb.org/?gene=A0A3Q1LL79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M5D2", "url": "https://www.orthodb.org/?gene=A0A3Q1M5D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MKX4", "url": "https://www.orthodb.org/?gene=A0A3Q1MKX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF108", 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LLD7-1", "uniprot_ac": "A0A3Q1LLD7", "uniprot_id": "A0A3Q1LLD7_BOVIN", "mass": { "chemical_mass": 62336.0, "monoisotopic_mass": 62336.0 }, "refseq": {}, "gene_names": [ { "name": "GPR107", "type": "recommended", "evidence": [ { "id": "A0A3Q1LLD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 107", "type": "synonym", "evidence": [ { "id": "A0A3Q1LLD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR107", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7", "locus": { "chromosome": "11", "start_pos": 100469997, "end_pos": 100410491, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004204", "url": "https://www.ensembl.org/id/ENSBTAG00000004204" } ] } } ], "crossref": [ { "id": "A0A3Q1LLD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LLD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004204", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004204", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR009637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GIHEEAW", "url": "https://omabrowser.org/oma/group/GIHEEAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21229:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21229:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MT29", "url": "https://www.uniprot.org/uniprotkb/F1MT29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MT29-1", "url": "https://www.uniprot.org/uniprotkb/F1MT29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPAPVGLSGSRSPRLASGLRLFPLLGLLQLLAEPGLGRVHHLALKDDVRHKVHLNTFGFFKNGYMKVNVSSLSVNEPKGATDKDFTIGFSLDRTKNDGFSSYLDEDVNYCILKKQSASVTLLILDISRSEVKIRSPPEAGAQLPKIIFTKDEKVVGQSQEPGVNPVSSGSQAPKEQESGKSKRSTVDSKATGEKSFSVHNNDGAVSFQFFFNISTDDQEGLYSLYFHKCLGSDAWSNDKFSFSLDIEITEKNPDSYLSAGEIPLPKLYISMAFFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKVFMVVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKLAVPFQWKWLYQLLDEMATLVFFVLTGYKFRPASDNPYLQLSQEEDDLEMESVVTTSGVMENMKKVKKVTNGSVEPQADWEGSA", "length": 556, "header": "tr|A0A3Q1LLD7-1|A0A3Q1LLD7_BOVIN Isoform 1 of G protein-coupled receptor 107 OS=Bos taurus OX=9913 GN=GPR107 PE=4 SV=2 CANONICAL=A0A3Q1LLD7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7/entry", "sequence": { "sequence": "MAAPAPVGLSGSRSPRLASGLRLFPLLGLLQLLAEPGLGRVHHLALKDDVRHKVHLNTFGFFKNGYMKVNVSSLSVNEPKGATDKDFTIGFSLDRTKNDGFSSYLDEDVNYCILKKQSASVTLLILDISRSEVKIRSPPEAGAQLPKIIFTKDEKVVGQSQEPGVNPVSSGSQAPKEQESGKSKRSTVDSKATGEKSFSVHNNDGAVSFQFFFNISTDDQEGLYSLYFHKCLGSDAWSNDKFSFSLDIEITEKNPDSYLSAGEIPLPKLYISMAFFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKVFMVVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKLAVPFQWKWLYQLLDEMATLVFFVLTGYKFRPASDNPYLQLSQEEDDLEMESVVTTSGVMENMKKVKKVTNGSVEPQADWEGSA", "length": 556, "header": "tr|A0A3Q1LLD7-1|A0A3Q1LLD7_BOVIN Isoform 1 of G protein-coupled receptor 107 OS=Bos taurus OX=9913 GN=GPR107 PE=4 SV=2 CANONICAL=A0A3Q1LLD7-1" }, "locus": { "chromosome": "11", "start_pos": 100462718, "end_pos": 100410518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080655.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080655.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057562.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057562.2" } ] } }, { "isoform_ac": "F1MT29-1", "url": "https://www.uniprot.org/uniprotkb/F1MT29/entry", "sequence": { "sequence": "MAAPAPVGLSGSRSPRLASGLRLFPLLGLLQLLAEPGLGRVHHLALKDDVRHKVHLNTFGFFKNGYMKVNVSSLSVNEPKGATDKDFTIGFSLDRTKNDGFSSYLDEDVNYCILKKQSASVTLLILDISRSEVKIRSPPEAGAQLPKIIFTKDEKVVGQSQEPGVNPVSSGSQAPKEQESGKSKRSTVDSKATGEKSFSVHNNDGAVSFQFFFNISTDDQEGLYSLYFHKCLGSDAWSNDKFSFSLDIEITEKNPDSYLSAGEIPLPKLYISMAFFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKVFMVVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKGDSKGPLEWRASLRAGSREAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKLAVPFQWKWLYQLLDEMATLVFFVLTGYKFRPASDNPYLQLSQEEDDLEMESVVTTSGVMENMKKVKKVTNGSVEPQADWEGSA", "length": 575, "header": "tr|F1MT29-1|F1MT29_BOVIN Computationally mapped isoform of G protein-coupled receptor 107 OS=Bos taurus OX=9913 GN=GPR107 PE=4 SV=2 CANONICAL=A0A3Q1LLD7-1" }, "locus": { "chromosome": "11", "start_pos": 100462718, "end_pos": 100410518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005512.7", "url": "https://www.ensembl.org/id/ENSBTAT00000005512.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005512.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005512.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZWZ9-1", "protein_name": "Protein GPR107", "gene_name": "Gpr107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVRVPLGCTGSFCPRLLPLLALLELLVDPSLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNISSLSVNEPEGVKDKDTEIGFSLDRTKNDGFSSYLDEDVNYCILKKKSMSSVTLLILDISGSGVKVRSPPEAGKQLPEIVFSKDEKVPSRSQEPAVSSNPKDSKVQRTPDGSKAQRSTVDSKTIAEKFFSIHKNDGAVSFQFFFNISTSDQEGLYSLYFHKCPSSKLRSGEQVSFSLNIDITEKNPDSYLSAGEIPLPKLYVSMALLFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKFAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEDDLEMESVVTTSGVMENMKKVKKVSNGAVEPQGSWEGTA", "length": 551 }, "evidence": [ { "id": "A0A3Q1LLD7", "url": "https://omabrowser.org/oma/group/A0A3Q1LLD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VW38-1", "protein_name": "Protein GPR107", "gene_name": "GPR107", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALAPVGSPASRGPRLAAGLRLLPMLGLLQLLAEPGLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNVSSLSLNEPEDKDVTIGFSLDRTKNDGFSSYLDEDVNYCILKKQSVSVTLLILDISRSEVRVKSPPEAGTQLPKIIFSRDEKVLGQSQEPNVNPASAGNQTQKTQDGGKSKRSTVDSKAMGEKSFSVHNNGGAVSFQFFFNISTDDQEGLYSLYFHKCLGKELPSDKFTFSLDIEITEKNPDSYLSAGEIPLPKLYISMAFFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKGDSMGPLQQRANLRAGSRIESHHFAQADLELLASSCPPASVSQRAGITAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKLAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEEDLEMESVVTTSGVMESMKKVKKVTNGSVEPQGEWEGAV", "length": 600 }, "evidence": [ { "id": "A0A3Q1LLD7", "url": "https://omabrowser.org/oma/group/A0A3Q1LLD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BUV8-1", "protein_name": "Protein GPR107", "gene_name": "Gpr107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVPVPLGRFGSFCLRLLRLLALLELLVHPVLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNVSSLSVNEPEGATDKDAEIGFSLDRTKNDGFSSYLDEDVNYCILKKKSMSSVTLVILDISGSIVKVRSPPEAGKQLPEIVFSKDEKILSQSQEPAVSSNPKDSEARRTLDGFKAGRSTVDSKAITERSFSIHKNDGVVSFQFFFNISTDDQEGLYSLYFHKCSGNNVKPGEQASFSLNIAITEKNPNSYLSAGEIPLPKLYVSMALFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLRLFRHYYVLIVCYIYFTRIIAFLLKFAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEDDDLEMESVVTTSGVMENMKKVKKVSNGAVEPQGSWEGTA", "length": 551 }, "evidence": [ { "id": "A0A3Q1LLD7", "url": "https://omabrowser.org/oma/group/A0A3Q1LLD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin heavy chain binding", "id": "GO:0032050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032050", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LLD7", "database": "UniProtKB", "url": 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} ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LLH8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYW8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYW8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSBTAP00000102433.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:616118", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616118", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLH8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLH8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": 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"Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", 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"P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": 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"name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLN7" } ], "pmid": "" }, { "name": "purine nucleoside metabolic process", "id": "GO:0042278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042278", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLN7" } ], "pmid": "" }, { "name": "peptidyl-glutamate ADP-deribosylation", "id": "GO:0140291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140291", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "deacetylase activity", "id": "GO:0019213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019213", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLN7", "url": 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"Q1LZ74-1", "Q2KHU5-1", "F1MWJ3-1" ], "evidence": [ { "id": "68792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68792" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MWJ3", "gene_name": "ADPRS", "activity": [ { "ec_number": "3.2.1.143", "activity": "[(1''->2')-ADP-alpha-D-ribose](n) + H2O = [(1''->2')-ADP-alpha-D-ribose](n-1) + ADP-D-ribose.", "evidence": [ { "id": "F1MWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWJ3" } ] }, { "ec_number": "3.2.1.143", "activity": "", "evidence": [ { "id": "F1MWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWJ3" } ] } ] }, { "uniprot_ac": "Q1LZ74", "gene_name": "OARD1", "activity": [ { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "Q1LZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZ74" } ] }, { "ec_number": "3.2.2.-", "activity": "", "evidence": [ { "id": "Q1LZ74", "database": "UniProtKB", "url": 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"monoisotopic_mass": 160849.0 }, "refseq": {}, "gene_names": [ { "name": "KIF7", "type": "recommended", "evidence": [ { "id": "A0A3Q1LM07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM07" } ] } ], "protein_names": [ { "name": "Kinesin family member 7", "type": "synonym", "evidence": [ { "id": "A0A3Q1LM07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM07/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM07" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KIF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM07", "locus": { "chromosome": "21", "start_pos": 21056492, "end_pos": 21074297, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002440", "url": "https://www.ensembl.org/id/ENSBTAG00000002440" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002440", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002440", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01372", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01372", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538808", "url": "https://www.ncbi.nlm.nih.gov/gene/538808", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LM07", "url": "https://www.orthodb.org/?gene=A0A3Q1LM07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47969:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47969:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5632684", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5632684", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LM07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMD2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMD2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUH2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N061", "url": "https://www.uniprot.org/uniprotkb/F1N061", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N061-1", "url": "https://www.uniprot.org/uniprotkb/F1N061-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLEAQRLPGAEEAPVRVALRVRPLLRKELLHGHQSCLTVEPGRSRVTLGRDRHFGFHVVLDEDAGQEAVYQACVQPLLEAFFEGFNVTVFAYGQTGSGKTYTMGEASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNRLSSRSHTIFTVTLEQRGRAPSRLPRPAAGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTMMIACISPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERGPEEAVASARGPPRHRSETRIIHRGRRAPGPAAASAAATARLGAECARYRARTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASAEEQATQGPGGRKEDEGPLQLLALQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMAELRLRLELVWPGWGAPGILQGLPPGSFVPRPHTAPLGGAHTHVLGMVPPACIPGDEVGPESRGEMKNGREAGAKFLTEGDRPGSGSSDASEAEEEEEEEEKEGLPRQSLYPRRNGVSKWNQRMGACPESPLNRKGPELRLEELGAAIPGPRGELGGAQRGSQPLYPLMVLDWPPWRVHIPSLAAPGQGSPPLPSVPATPASPTICRGSRPDRQPVTVVGGSKALAQPRQAPAAMASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIQELEREAERVRAELSEGQRQLWELEGREPQDAGERSQLQEFRKRVAAAQNQVQVLKEKKQATERLASLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDALRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQVAFSELELQLEEQQRLVYWLEAALERQRLEMDRQLTLQQRGHEQHVQLLLQQSRGGARARHGGCRLPCSPSPPPPAFFSPDHLGEGLADSRRQYETRIQALEKELGRHVRLNQELKQKLSSLSAASQSRVMGGEKRTPCLENRQAPGSEDELYPAPEPLWQPTGMEGAPRPREEMRDLVHAPLPLTWKRSSLCSEEQGSPEELRQRDAAELPVGRVLPVGEAGLPWNLGPLAKPRRELRRVSPGMIDVRKNPL", "length": 1440, "header": "tr|A0A3Q1LM07-1|A0A3Q1LM07_BOVIN Isoform 1 of Kinesin family member 7 OS=Bos taurus OX=9913 GN=KIF7 PE=3 SV=2 CANONICAL=A0A3Q1LM07-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LM07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM07/entry", "sequence": { "sequence": "MGLEAQRLPGAEEAPVRVALRVRPLLRKELLHGHQSCLTVEPGRSRVTLGRDRHFGFHVVLDEDAGQEAVYQACVQPLLEAFFEGFNVTVFAYGQTGSGKTYTMGEASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNRLSSRSHTIFTVTLEQRGRAPSRLPRPAAGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTMMIACISPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERGPEEAVASARGPPRHRSETRIIHRGRRAPGPAAASAAATARLGAECARYRARTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASAEEQATQGPGGRKEDEGPLQLLALQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMAELRLRLELVWPGWGAPGILQGLPPGSFVPRPHTAPLGGAHTHVLGMVPPACIPGDEVGPESRGEMKNGREAGAKFLTEGDRPGSGSSDASEAEEEEEEEEKEGLPRQSLYPRRNGVSKWNQRMGACPESPLNRKGPELRLEELGAAIPGPRGELGGAQRGSQPLYPLMVLDWPPWRVHIPSLAAPGQGSPPLPSVPATPASPTICRGSRPDRQPVTVVGGSKALAQPRQAPAAMASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIQELEREAERVRAELSEGQRQLWELEGREPQDAGERSQLQEFRKRVAAAQNQVQVLKEKKQATERLASLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDALRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQVAFSELELQLEEQQRLVYWLEAALERQRLEMDRQLTLQQRGHEQHVQLLLQQSRGGARARHGGCRLPCSPSPPPPAFFSPDHLGEGLADSRRQYETRIQALEKELGRHVRLNQELKQKLSSLSAASQSRVMGGEKRTPCLENRQAPGSEDELYPAPEPLWQPTGMEGAPRPREEMRDLVHAPLPLTWKRSSLCSEEQGSPEELRQRDAAELPVGRVLPVGEAGLPWNLGPLAKPRRELRRVSPGMIDVRKNPL", "length": 1440, "header": "tr|A0A3Q1LM07-1|A0A3Q1LM07_BOVIN Isoform 1 of Kinesin family member 7 OS=Bos taurus OX=9913 GN=KIF7 PE=3 SV=2 CANONICAL=A0A3Q1LM07-1" }, "locus": { "chromosome": "21", "start_pos": 21072078, "end_pos": 21057496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075908.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075908.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057664.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057664.2" } ] } }, { "isoform_ac": "A0ABI0NMD2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMD2/entry", "sequence": { "sequence": "MGLEAQRLPGAEEAPVRVALRVRPLLRKELLHGHQSCLTVEPGRSRVTLGRDRHFGFHVVLDEDAGQEAVYQACVQPLLEAFFEGFNVTVFAYGQTGSGKTYTMGEASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNRLSSRSHTIFTVTLEQRGRAPSRLPRPAAGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTMMIACISPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERGPEEAVASARGPPRHRSETRIIHRGRRAPGPAAASAAATARLGAECARYRARTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASAEEQATQGPGGRKEDEGPLQLLALQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMAELRLRLELVWPGWGAPGILQGLPPGSFVPRPHTAPLGGAHTHVLGMVPPACIPGDEVGPESRGEMKNGREAGAKFLTEGDRPGSGSSDASEAEEEEEEEEKEGLPRQSLYPRRNGVSKWNQRMGACPESPLNRKGPELRLEELGAAIPGPRVVGGSKALAQPRQAPAAMASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIQELEREAERVRAELSEGQRQLWELEGREPQDAGERSQLQEFRKRVAAAQNQVQVLKEKKQATERLASLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDALRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQVAFSELELQLEEQQRLVYWLEAALERQRLEMDRQLTLQQRGHEQHVQLLLQQSRDHLGEGLADSRRQYETRIQALEKELGRHVRLNQELKQKLSSLSAASQSRVMGGEKRTPCLENRQAPGSEDELYPAPEPLWQPTGMEGAPRPREEMRDLVHAPLPLTWKRSSLCSEEQGSPEELRQRDAAELPVGRVLPVGEAGLPWNLGPLAKPRRELRRVSPGMIDVRKNPL", "length": 1349, "header": "tr|A0ABI0NMD2-1|A0ABI0NMD2_BOVIN Computationally mapped isoform of Kinesin family member 7 OS=Bos taurus OX=9913 GN=KIF7 PE=3 SV=1 CANONICAL=A0A3Q1LM07-1" }, "locus": { "chromosome": "21", "start_pos": 21072078, "end_pos": 21057496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152097.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152097.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106257.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106257.1" } ] } }, { "isoform_ac": "A0ABI0NUH2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUH2/entry", "sequence": { "sequence": "MGLEAQRLPGAEEAPVRVALRVRPLLRKELLHGHQSCLTVEPGRSRVTLGRDRHFGFHVVLDEDAGQEAVYQACVQPLLEAFFEGFNVTVFAYGQTGSGKTYTMGEASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNRLSSRSHTIFTVTLEQRGRAPSRLPRPAAGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTMMIACISPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERGPEEAVASARGPPRHRSETRIIHRGRRAPGPAAASAAATARLGAECARYRARTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASAEEQATQGPGGRKEDEGPLQLLALQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMAELRLRLELVWPGWGAPGILQGLPPGSFVPRPHTAPLGGAHTHVLGMVPPACIPGDEVGPESRGEQMKNGREAGAKFLTEGDRPGSGSSDASEAEEEEEEEEKEGLPRQSLYPRRNGVSKWNQRMGACPESPLNRKGPELRLEELGAAIPGPRVVGGSKALAQPRQAPAAMASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIQELEREAERVRAELSEGQRQLWELEGREPQDAGERSQLQEFRKRVAAAQNQVQVLKEKKQATERLASLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDALRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQVAFSELELQLEEQQRLVYWLEAALERQRLEMDRQLTLQQRGHEQHVQLLLQQSRDHLGEGLADSRRQYETRIQALEKELGRHVRLNQELKQKLSSLSAASQSRVMGGEKRTPCLENRQAPGSEDELYPAPEPLWQPTGMEGAPRPREEMRDLVHAPLPLTWKRSSLCSEEQGSPEELRQRDAAELPVGRVLPVGEAGLPWNLGPLAKPRRELRRVSPGMIDVRKNPL", "length": 1350, "header": "tr|A0ABI0NUH2-1|A0ABI0NUH2_BOVIN Computationally mapped isoform of Kinesin family member 7 OS=Bos taurus OX=9913 GN=KIF7 PE=3 SV=1 CANONICAL=A0A3Q1LM07-1" }, "locus": { "chromosome": "21", "start_pos": 21072078, "end_pos": 21057496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152043.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152043.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104092.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104092.1" } ] } }, { "isoform_ac": "F1N061-1", "url": "https://www.uniprot.org/uniprotkb/F1N061/entry", "sequence": { "sequence": "MIERPSERLQGWEQQSLNMGLEAQRLPGAEEAPVRVALRVRPLLRKELLHGHQSCLTVEPGRSRVTLGRDRHFGFHVVLDEDAGQEAVYQACVQPLLEAFFEGFNVTVFAYGQTGSGKTYTMGEASVASLHEDEQGIIPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNRLSSRSHTIFTVTLEQRGRAPSRLPRPAAGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTMMIACISPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERGPEEAVASARGPPRHRSETRIIHRGRRAPGPAAASAAATARLGAECARYRARTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASAEEQATQGPGGRKEDEGPLQLLALQSQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMAELRLRLELVWPGWGAPGILQGLPPGSFVPRPHTAPLGGAHTHVLGMVPPACIPGDEVGPESRGEMKNGREAGAKFLTEGDRPGSGSSDASEAEEEEEEEEKEGLPRQSLYPRRNGVSKWNQRMGACPESPLNRKGPELRLEELGAAIPGPRVVGGSKALAQPRQAPAAMASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIQELEREAERVRAELSEGQRQLWELEGREPQDAGERSQLQEFRKRVAAAQNQVQVLKEKKQATERLASLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMNKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDALRQEKDSLLKQRLEIDSKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQVAFSELELQLEEQQRLVYWLEAALERQRLEMDRQLTLQQRGHEQHVQLLLQQSRDHLGEGLADSRRQYETRIQALEKELGRHVRLNQELKQKLSSLSAASQSRVMGGEKRTPCLENRQAPGSEDELYPAPEPLWQPTGMEGAPRPREEMRDLVHAPLPLTWKRSSLCSEEQGSPEELRQRDAAELPVGRVLPVGEAGLPWNLGPLAKPRRELRRVSPGMIDVRKNPL", "length": 1367, "header": "tr|F1N061-1|A0A3Q1LM07_BOVIN Computationally mapped isoform of Kinesin family member 7 OS=Bos taurus OX=9913 GN=KIF7 PE=3 SV=3 CANONICAL=A0A3Q1LM07-1" }, "locus": { "chromosome": "21", "start_pos": 21073946, "end_pos": 21057496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009103.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009103.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009103.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009103.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 730, "start_aa": "Thr", "end_pos": 730, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr730", "evidence": [ { "id": 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"tr|A0A3Q1LM20-1|A0A3Q1LM20_BOVIN Isoform 1 of Histone H4 OS=Bos taurus OX=9913 GN=LOC115945178 PE=3 SV=1 CANONICAL=A0A3Q1LM20-1" }, "locus": { "chromosome": "NKLS02001234.1", "start_pos": 2702, "end_pos": 2295, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071691.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071691.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057681.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057681.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:115945178", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:115945178", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3N081-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTL", "length": 98 }, "evidence": [ { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" }, { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" }, { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P02309-1", "protein_name": "Histone H4", "gene_name": "HHF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P59259-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" }, { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P62801-1", "protein_name": "Histone H4", "gene_name": "H4-I", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P62804-1", "protein_name": "Histone H4", "gene_name": "H4c16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" }, { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62806-1", "protein_name": "Histone H4", "gene_name": "H4c2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" }, { "id": "A0A3Q1LM20", "url": "https://omabrowser.org/oma/group/A0A3Q1LM20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM20" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM20" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM20" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM20" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LM20-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 136, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LM20-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LM20" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LM42-1", "uniprot_ac": "A0A3Q1LM42", "uniprot_id": "A0A3Q1LM42_BOVIN", "mass": { "chemical_mass": 91785.0, "monoisotopic_mass": 91785.0 }, "refseq": { "ac": "XP_010806298", "name": "ankyrin repeat and SAM domain-containing protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806298" }, "gene_names": [ { "name": "ANKS6", "type": "recommended", "evidence": [ { "id": "A0A3Q1LM42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42" } ] }, { "name": "ANKS6", "type": "synonym", "evidence": [ { "id": "XP_010806298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806298" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and SAM domain-containing protein 6", "type": "recommended", "evidence": [ { "id": "A0A3Q1LM42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42/entry#names_and_taxonomy" } ] }, { "name": "SamCystin", "type": "synonym", "evidence": [ { "id": "A0A3Q1LM42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42/entry#names_and_taxonomy" } ] }, { "name": "Sterile alpha motif domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "A0A3Q1LM42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and SAM domain-containing protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010806298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806298" } ] } ], "function": [ { "annotation": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42#function" }, { "database": "UniProtKB", "id": "ARBA00025297", "url": "https://www.uniprot.org/uniprotkb/ARBA00025297#function" } ] }, { "annotation": "Required for renal function.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42#function" }, { "database": "UniProtKB", "id": "ARBA00054970", "url": "https://www.uniprot.org/uniprotkb/ARBA00054970#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANKS6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42", "locus": { "chromosome": "8", "start_pos": 63786524, "end_pos": 63836540, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005133", "url": "https://www.ensembl.org/id/ENSBTAG00000005133" } ] } } ], "crossref": [ { "id": "A0A3Q1LM42", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LM42", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005133", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005133", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09518", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09518", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "530846", "url": "https://www.ncbi.nlm.nih.gov/gene/530846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LM42", "url": "https://www.orthodb.org/?gene=A0A3Q1LM42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MNU9", "url": "https://www.orthodb.org/?gene=F1MNU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23206:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23206:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010806298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM42-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MNU9", "url": "https://www.uniprot.org/uniprotkb/F1MNU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MNU9-1", "url": "https://www.uniprot.org/uniprotkb/F1MNU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEGGLPPAFQLLLRACDQGDTETARRLLDPGAAEPAERGVEPEAGAEPAGPEAAGPGAAAGAPVPVDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHKPSGEADSGDELLDITALMAAIQHGHEAVVRLLMEWGADPNHEARTVGWSPLMLSALIGKLGMAQQLVEKGANPDHLSVLEKTAFEVALDRKHRDLADYLDPLTTVRPKTDEEKRRPDIFHALKMGNFQLVKEIADEDPNHVNLVNGDGATPLMLAAVMGQLPLVQLLVERHADVDKQDSAHGWTALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLSDPDTELVRLLASVCMQVNKDKGRPSHPPPLPHSKVRQPWSVPVLPDDKGGLKSWWNRMSNRFRKLKLMQTLPRGLSSNQPLPFCDEPEPALDSTMRAAPLDKTSRSGLPDVAPMTKDNGTGSTRGEKEDVLLTTMLRNGAPFTRLPSDKLKAVIPPFLPPSSFELWSSDHSRTCHNGKADPMKTVLPQRAGRGHPAGGGSTDSTLVRPVKFPSLSRSPASPANSGNFNHSPHSSGGSSGGGGMSRHGGELHNRSGGSVDSVLSQIAAQRKKAAGLSEQKPSHRSSPVGPAPSSSPSELPVSPAGGSVPGGKQKLETSKRPPSGTSTTSKSTSPTLTPSPSPKGHAAESSVSSSSSHRQSKGSGGSSSGTITDEDELTGILKKLSLEKYQPIFEEQEVDMEAFLTLTDGDLKELGIKTDGSRQQILAAISELNAGKGRERQILQETIHNFHSSFESSASNTRAPGNNPCT", "length": 865, "header": "tr|A0A3Q1LM42-1|A0A3Q1LM42_BOVIN Isoform 1 of Ankyrin repeat and SAM domain-containing protein 6 OS=Bos taurus OX=9913 GN=ANKS6 PE=4 SV=2 CANONICAL=A0A3Q1LM42-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LM42-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42/entry", "sequence": { "sequence": "MGEGGLPPAFQLLLRACDQGDTETARRLLDPGAAEPAERGVEPEAGAEPAGPEAAGPGAAAGAPVPVDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHKPSGEADSGDELLDITALMAAIQHGHEAVVRLLMEWGADPNHEARTVGWSPLMLSALIGKLGMAQQLVEKGANPDHLSVLEKTAFEVALDRKHRDLADYLDPLTTVRPKTDEEKRRPDIFHALKMGNFQLVKEIADEDPNHVNLVNGDGATPLMLAAVMGQLPLVQLLVERHADVDKQDSAHGWTALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLSDPDTELVRLLASVCMQVNKDKGRPSHPPPLPHSKVRQPWSVPVLPDDKGGLKSWWNRMSNRFRKLKLMQTLPRGLSSNQPLPFCDEPEPALDSTMRAAPLDKTSRSGLPDVAPMTKDNGTGSTRGEKEDVLLTTMLRNGAPFTRLPSDKLKAVIPPFLPPSSFELWSSDHSRTCHNGKADPMKTVLPQRAGRGHPAGGGSTDSTLVRPVKFPSLSRSPASPANSGNFNHSPHSSGGSSGGGGMSRHGGELHNRSGGSVDSVLSQIAAQRKKAAGLSEQKPSHRSSPVGPAPSSSPSELPVSPAGGSVPGGKQKLETSKRPPSGTSTTSKSTSPTLTPSPSPKGHAAESSVSSSSSHRQSKGSGGSSSGTITDEDELTGILKKLSLEKYQPIFEEQEVDMEAFLTLTDGDLKELGIKTDGSRQQILAAISELNAGKGRERQILQETIHNFHSSFESSASNTRAPGNNPCT", "length": 865, "header": "tr|A0A3Q1LM42-1|A0A3Q1LM42_BOVIN Isoform 1 of Ankyrin repeat and SAM domain-containing protein 6 OS=Bos taurus OX=9913 GN=ANKS6 PE=4 SV=2 CANONICAL=A0A3Q1LM42-1" }, "locus": { "chromosome": "8", "start_pos": 63836341, "end_pos": 63787528, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082607.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082607.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057898.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057898.2" } ] } }, { "isoform_ac": "F1MNU9-1", "url": "https://www.uniprot.org/uniprotkb/F1MNU9/entry", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LM42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LM42-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 865, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LM42-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LM42" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LM42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM42" }, { "id": "PS50105", 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"https://alphafold.ebi.ac.uk/entry/A0A3Q1LM71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049638", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049638", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12589:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12589:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LM71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM71-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSHEWPGLGSSPMGTSVPPRLFGTTHHPHSKSLSDEEDLKLFGKCHNTHTFKVPGEIGPVTGMVLNLTDLQEYTEEAIMKYLGLDVPYFADIVSTTENVDIYTWENLQKFLPVGVLDKIKVYETNNNIVVYKGK", "length": 135, "header": "tr|A0A3Q1LM71-1|A0A3Q1LM71_BOVIN Isoform 1 of 6-pyruvoyltetrahydropterin synthase OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0A3Q1LM71-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LM71-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM71/entry", "sequence": { "sequence": "MSSHEWPGLGSSPMGTSVPPRLFGTTHHPHSKSLSDEEDLKLFGKCHNTHTFKVPGEIGPVTGMVLNLTDLQEYTEEAIMKYLGLDVPYFADIVSTTENVDIYTWENLQKFLPVGVLDKIKVYETNNNIVVYKGK", "length": 135, "header": "tr|A0A3Q1LM71-1|A0A3Q1LM71_BOVIN Isoform 1 of 6-pyruvoyltetrahydropterin synthase OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0A3Q1LM71-1" }, "locus": { "chromosome": "16", "start_pos": 77228435, "end_pos": 77227280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082350.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082350.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060956.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060956.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM71" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM71" } ], "pmid": "" }, { "name": "6-pyruvoyltetrahydropterin synthase activity", "id": "GO:0003874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003874", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tetrahydrobiopterin biosynthetic process", "id": "GO:0006729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006729", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LM83-1", "uniprot_ac": "A0A3Q1LM83", "uniprot_id": "A0A3Q1LM83_BOVIN", "mass": { "chemical_mass": 93950.0, "monoisotopic_mass": 93950.0 }, "refseq": { "ac": "XP_024854400", "name": "serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024854400" }, "gene_names": [ { "name": "PPP4R3B", "type": "recommended", "evidence": [ { "id": "A0A3Q1LM83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ] }, { "name": "PPP4R3B", "type": "synonym", "evidence": [ { "id": "XP_024854400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024854400" } ] }, { "name": "SMEK2", "type": "synonym", "evidence": [ { "id": "XP_024854400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024854400" } ] } ], "protein_names": [ { "name": "Protein phosphatase 4 regulatory subunit 3B", "type": "synonym", "evidence": [ { "id": "A0A3Q1LM83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024854400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024854400" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPP4R3B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83", "locus": { "chromosome": "11", "start_pos": 38245095, "end_pos": 38297358, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000545", "url": "https://www.ensembl.org/id/ENSBTAG00000000545" } ] } } ], "crossref": [ { "id": "A0A3Q1LM83", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LM83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000545", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "516489", "url": "https://www.ncbi.nlm.nih.gov/gene/516489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516489", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516489", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHRYMIS", "url": "https://omabrowser.org/oma/group/YHRYMIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LM83", "url": "https://www.orthodb.org/?gene=A0A3Q1LM83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BFZ3", "url": "https://www.orthodb.org/?gene=E1BFZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23318:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23318:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04802", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04802", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024854400", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024854400", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3U8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3U8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFZ3", "url": "https://www.uniprot.org/uniprotkb/E1BFZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFZ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSIYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDRREKDNVVGSNKSSTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVVNALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDEEEGKTVVAPVEKSKAEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSTSAANGANSTNSKSVVAQTPPASSNGSSSKTTNLATSVTATKGSLVGLVDYPDDEEEEEEEETSPRKRPRLGS", "length": 820, "header": "tr|A0A3Q1LM83-1|A0A3Q1LM83_BOVIN Isoform 1 of Protein phosphatase 4 regulatory subunit 3B OS=Bos taurus OX=9913 GN=PPP4R3B PE=3 SV=1 CANONICAL=A0A3Q1LM83-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LM83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83/entry", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSIYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDRREKDNVVGSNKSSTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVVNALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDEEEGKTVVAPVEKSKAEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSTSAANGANSTNSKSVVAQTPPASSNGSSSKTTNLATSVTATKGSLVGLVDYPDDEEEEEEEETSPRKRPRLGS", "length": 820, "header": "tr|A0A3Q1LM83-1|A0A3Q1LM83_BOVIN Isoform 1 of Protein phosphatase 4 regulatory subunit 3B OS=Bos taurus OX=9913 GN=PPP4R3B PE=3 SV=1 CANONICAL=A0A3Q1LM83-1" }, "locus": { "chromosome": "11", "start_pos": 38296255, "end_pos": 38245330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067169.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067169.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060973.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060973.1" } ] } }, { "isoform_ac": "A0AAA9S3U8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3U8/entry", "sequence": { "sequence": "MECEHISFPSAHGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDRREKDNVVGSNKSSTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVVNALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDEEEGKTVVAPVEKSKAEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSTSAANGANSTNSKSVVAQTPPASSNGSSSKTTNLATSVTATKGSLVGLVDYPDDEEEEEEEETSPRKRPRLGS", "length": 785, "header": "tr|A0AAA9S3U8-1|A0A3Q1LM83_BOVIN Computationally mapped isoform of Protein phosphatase 4 regulatory subunit 3B OS=Bos taurus OX=9913 GN=PPP4R3B PE=3 SV=1 CANONICAL=A0A3Q1LM83-1" }, "locus": { "chromosome": "11", "start_pos": 38297042, "end_pos": 38245330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090002.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090002.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079778.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079778.1" } ] } }, { "isoform_ac": "E1BFZ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BFZ3/entry", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSIYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDRREKDNVVGSNKSSTICPGALRFMRRIIGLKDEFYNRYITKGNLFEPVVNALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDEEEGKTVVAPVEKSKAEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSTSAANGANSTNSKSVVAQTPPASSNGSSSKTTNLATSVTATKGSLVGLVDYPDDEEEEEEEETSPRKRPRLGS", "length": 767, "header": "tr|E1BFZ3-1|A0A3Q1LM83_BOVIN Computationally mapped isoform of Protein phosphatase 4 regulatory subunit 3B OS=Bos taurus OX=9913 GN=PPP4R3B PE=3 SV=3 CANONICAL=A0A3Q1LM83-1" }, "locus": { "chromosome": "11", "start_pos": 38296255, "end_pos": 38245330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000709.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000709.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000709.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000709.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:516489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516489", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZCR4-1", "protein_name": "Protein phosphatase 4, regulatory subunit 3B", "gene_name": "Ppp4r3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEESVEDHIVEDQIGISPMRSDTDPRPALGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHQLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNMLGSNKTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDDEEGKSVVTPVEKTKTEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSPSAANGTNSTNSKSVVAQTTPASSNGSSSKTTNLATSVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS", "length": 803 }, "evidence": [ { "id": "A0A3Q1LM83", "url": "https://omabrowser.org/oma/group/A0A3Q1LM83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SQL1-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3B", "gene_name": "PPP4R3B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHMIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDRCEKDNVVGSNKNSTVCPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKTLEEDEEMWFNEDEEEEGKPVVASVEKSKPEDDFPDSYEKFMETKKAKESEDKENLPKRTSSGGFKFTFSHSTSAANGTNSTNSKSVVAQSPPASSNGSSSKTTNLATTVTATKGSLVGLVDYPDDEEEDEEEETSPRKRPRLGS", "length": 820 }, "evidence": [ { "id": "A0A3Q1LM83", "url": "https://omabrowser.org/oma/group/A0A3Q1LM83/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4JC31-1", "protein_name": "Binding protein", "gene_name": "SMEK1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGAPEKSQSNTNSMQRVKVYHLNEDGKWDDRGTGHVSIDFVERSEELSLCVIDEEDNETLLVHPINPEDIYRKQEDTIISWRDPERSTELALSFQETAGCSYVWDQICTMQRNLHFSSLNSETFHSLNSELRELPAVELTTLPLILKIVTESGITDQMRLTELILKDHDFFRNLMGVFKICEDLENVDGLHMIFNIVKGIILLNSSQILEKIFGDELIMEIIGCLEYDPGVPHSQHHRNFLKEHVVFKERQSHVFFVRKEHAHYGCFGISAIPIKDPLVLSKIHQTYRIGYLKDVVLARVLDDAIVANLNSVIHANNAIVVSLLKDDSTFIQELFARLRSPSTSMESKKNLVYFLHEFCSLSKSLQVVQQLRLFRDLINEGIFHVIEEVLQIPDKKLVLTGTDILILFLTQDPNLLRSYVVRTEGNPLLGLLVKGMMEDFGDKMHCQFLEIIRTLLDANALSGGAQRANIMDIFYEKHLPELVDVITASCPEKSSNASEGAARRIFTKPEVLLNICELLCFCIMQDASRTKCSFLQNNVTEKVLHLTRRKEKYLVVAAIRFVRTLLSVHDDYVQNYVVKNNLLKPIIDVFIANGTRYNLLNSAVLDLLEHIRKGNATLLLKYIVDTFWDQLAPFQCLTSIQAFKVKYEQCLESAGPKSTSDAVDPRRRVDERALEKEEEDYFNEDSDEEDSASASNTQKEKPASNIQKEQPKPHLSNGVAASPTSSSPRSGGLVDYEDDEDDEDYKPPPRKQPEASEDEEGELLRLKRKSALVEREQEPSKKPRLGKSSKRENVFAVLCSTLSHAVLTGKKSPGPAGSAARSIVAKGAEDSKSSEENNSSSSDDENHKDDGVSSSEHETSDNGKLNGEESLVVAPKSSPEMAVNGS", "length": 886 }, "evidence": [ { "id": "A0A3Q1LM83", "url": "https://omabrowser.org/oma/group/A0A3Q1LM83/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P40164-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3", "gene_name": "PSY2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLPGTPTTSPTPMDEDTEQAVSVNTEPKRVKVYILENNEWKDTGTGFCIGEVDEGKFAYLVVSDEDSPTETLLKSKLEGNIEYQRQEETLIVWKDLGGKDIALSFEESMGCDTLCEFIVHVQRNIESNISLVTVKSSDNGLGSVHDIITGPVTLPSNDQQQNSQTLLEALKILNENTSFDFLKNETIEFILQSNYIDTLISHFHKAEEEKIPKDLFLLSNIIKTLILYNKRDILESMVEDDRIMGIVGILEYDTEYPTSKANHRKYLGSKGPNFKEVIPLENEDLKIIMKKCFRLQFLKDVVLVRFLDDHNFNLISEIVMDLETCIIDFLQVGTFLDRLIELYDTKTLPESSSEKEKFVQKRKDGIRLLQQCVQMSINLDAVDRSKFYKTLVRKGLFKVLDYAFHMETDSNVRILATDTIITIIEHDILLIHNVQNEDSFKRQHKSAPDDKSSHRKYPQDYSSSTDSKLLLILSTILLSDRSPGLREQVVQALNTLLHPEGCVGNGEGSYDLMGRSNYEAKNTSEDFPSFSYGLNSDSINLNNYHYSSDEMNNLEPESESEFQVMEYFANFYNKIAPILFGPLIKKDITTEMAEIDGQIEKVTKDDLLLIHLVKLVSFVCTEHDRVLSRRFILENGILDSVSKLIGGNHMMQLRLTAVRCIKNLMCLDDKYYHRYMISKNLYAPVFKLFQENIDKNNLANSCIQDFFRIIITECRAYQSDGHNRKEKTNGSYDGNGNDVKTNVNNNRTNFTILNKYLVQTYGDVLRKATDIPFIQDMLETGEENQPDHSSFENSIEGGNDISVNMSTDGFASNHLEDIDIKNVKRLHSEIEHFENDPHYSGDQLAFKKSVDQMNAST", "length": 858 }, "evidence": [ { "id": "A0A3Q1LM83", "url": "https://omabrowser.org/oma/group/A0A3Q1LM83/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5MIZ7-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3B", "gene_name": "PPP4R3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q922R5-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 3B", "gene_name": "Ppp4r3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPACELSKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDVLLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDNMLGSNTTNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDDDEEGKAVITPVEKSKTEDDFPDSYEKFMETKKAKESEDKENLPKRASSGGFKFTFSHSPSATNGTNSTNSKSVVSQTTPASSNVASSKTTSLATSVTATKGNLVGLVDYPDDEEEDEEEESSPRKRPRLGS", "length": 820 }, "evidence": [ { "id": "A0A3Q1LM83", "url": "https://omabrowser.org/oma/group/A0A3Q1LM83/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": 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"A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LM83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 279 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 455, "end_pos": 457 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 755, "end_pos": 757 }, { "start_pos": 772, "end_pos": 774 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LMF2-1", "uniprot_ac": "A0A3Q1LMF2", "uniprot_id": "A0A3Q1LMF2_BOVIN", "mass": { "chemical_mass": 34972.0, "monoisotopic_mass": 34972.0 }, "refseq": {}, "gene_names": [ { "name": "OR1J4F", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMF2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMF2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1J4F", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2", "locus": {} } ], "crossref": [ { "id": "A0A3Q1LMF2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000050201", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050201", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMF2", "url": "https://www.orthodb.org/?gene=A0A3Q1LMF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LMF2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "INRENHSSMSEFLLLGLPIQPEHQSMFFALFLGMYLTTVLGNVLILLLIRLDPHLHSPMYFFLSHLALTDVSFSSVIIPKMLVNMQTQDQSIPYPGCVTQMYFFLFFTNLDDFLLTSMAYDRYVAICHPLHYTTIMGQGLCTLLVTASWILSCASALCHTLLLTRLSFCADLSIPHFFCDLGALLKLSCSDTSFNELAIFTAGVAVIVLPLVCILISYGRIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYIFPSSSTSRDKITVVSVMYTVVTLLLNPFIHNLRNRDMKEALERLSHRAKVLFW", "length": 313, "header": "tr|A0A3Q1LMF2-1|A0A3Q1LMF2_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN=OR1J4F PE=3 SV=2 CANONICAL=A0A3Q1LMF2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMF2/entry", "sequence": { "sequence": 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"evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017310", "url": "https://www.ensembl.org/id/ENSBTAG00000017310" } ] } } ], "crossref": [ { "id": "A0A3Q1LMN4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017310", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017310", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22828", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22828", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516536", "url": "https://www.ncbi.nlm.nih.gov/gene/516536", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516536", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516536", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKRHVAC", "url": "https://omabrowser.org/oma/group/HKRHVAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMN4", "url": "https://www.orthodb.org/?gene=A0A3Q1LMN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPY6", "url": "https://www.orthodb.org/?gene=A0A3Q1LPY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LUI5", "url": "https://www.orthodb.org/?gene=A0A3Q1LUI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LX14", "url": "https://www.orthodb.org/?gene=A0A3Q1LX14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MY53", "url": "https://www.orthodb.org/?gene=A0A3Q1MY53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14851", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14851", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001185956", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185956", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPY6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUI5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MY53", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MY53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MY53-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MY53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0Q5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S729", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S729-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S729-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T460", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T460", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T460-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T460-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCL8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCL8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLPGHARPPSAPQPAQHPGLRRQVEPPGQLLRLFYCTVLVCSREIAALTDFSGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 441, "header": "tr|A0A3Q1LMN4-1|A0A3Q1LMN4_BOVIN Isoform 1 of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=2 CANONICAL=A0A3Q1LMN4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4/entry", "sequence": { "sequence": "MLLPGHARPPSAPQPAQHPGLRRQVEPPGQLLRLFYCTVLVCSREIAALTDFSGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 441, "header": "tr|A0A3Q1LMN4-1|A0A3Q1LMN4_BOVIN Isoform 1 of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=2 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3080424, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079419.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079419.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058143.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058143.2" } ] } }, { "isoform_ac": "A0A3Q1LPY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPY6/entry", "sequence": { "sequence": "HARPPSAPQPAQHPGLRRQVEPPGQLLRLFYCTVLVCSREIAALTDFSGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 406, "header": "tr|A0A3Q1LPY6-1|A0A3Q1LMN4_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=2 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3080409, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067003.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067003.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059013.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059013.2" } ] } }, { "isoform_ac": "A0A3Q1LUI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUI5/entry", "sequence": { "sequence": "MLLPGHARPPSAPQPAQHPGLRRQVEPPGQLLRLFYCTVLVCSREIAALTDFSGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 393, "header": "tr|A0A3Q1LUI5-1|A0A3Q1LMN4_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=1 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3080424, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076182.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076182.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060797.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060797.1" } ] } }, { "isoform_ac": "A0A3Q1LX14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX14/entry", "sequence": { "sequence": "VEPPGQLLRLFYCTVLVCSREIAALTDFSGNLPDPGIEPASPASPALAGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 436, "header": "tr|A0A3Q1LX14-1|A0A3Q1LX14_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=2 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3080352, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087205.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087205.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061756.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061756.2" } ] } }, { "isoform_ac": "A0A3Q1MY53-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MY53/entry", "sequence": { "sequence": "MTPSPGGLAAHLSEVPAGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 405, "header": "tr|A0A3Q1MY53-1|A0A3Q1LMN4_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=2 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3081847, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076987.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076987.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060886.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060886.2" } ] } }, { "isoform_ac": "A0AAA9S0Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0Q5/entry", "sequence": { "sequence": "MLLPGHARPPSAPQPAQHPGLRRQVEPPGQLLRLFYCTVLVCSREIAALTDFSGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRALSQHHLLRSGAAPERATPRPRSGAAAERSNSTSKEGWLRGRRRAERSYSTFKVRRGDLIQGKEQQLHFAGAAVQRYPASKVRETQVRR", "length": 405, "header": "tr|A0AAA9S0Q5-1|A0A3Q1LMN4_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=1 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3080424, "end_pos": 2954339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089323.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089323.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077220.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077220.1" } ] } }, { "isoform_ac": "A0AAA9S729-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S729/entry", "sequence": { "sequence": "MGILQARMLEWVAISSSKGSSQPRDRTCISYIGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 420, "header": "tr|A0AAA9S729-1|A0A3Q1LMN4_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=1 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3037204, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117747.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117747.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079715.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079715.1" } ] } }, { "isoform_ac": "A0AAA9T460-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T460/entry", "sequence": { "sequence": "MDPQVEPPGQLLRLFYCTVLVCSREIAALTDFSGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 421, "header": "tr|A0AAA9T460-1|A0A3Q1LMN4_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=1 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3081534, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097376.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097376.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090494.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090494.1" } ] } }, { "isoform_ac": "A0AAA9TCL8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCL8/entry", "sequence": { "sequence": "GHFHLATPCAFFRHHLPSGSLPASFLGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQKCSPQQPASQREDSLTCVVPTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKFLNIYSATYGRRTQERHVCSSEAERLPPFDCLSYSALHVLSRRCYGKQRCKVLVNNHHFGSPCLPGVKKYLSVFYACVPKNILTAIDPSVANLKPSVKQKDGDYGVDLDPREPRVLRKDGVIVSHSLAAFAYIRAHPERAALLFVSSVCVGLALTLCALVIRVSCTKDFQELQLAREHLVPGSDKAEEDSQDEEGEEDSSDSDFPGELSGFCRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 414, "header": "tr|A0AAA9TCL8-1|A0A3Q1LMN4_BOVIN Computationally mapped isoform of Protein eva-1 homolog C OS=Bos taurus OX=9913 GN=EVA1C PE=3 SV=1 CANONICAL=A0A3Q1LMN4-1" }, "locus": { "chromosome": "1", "start_pos": 3055817, "end_pos": 2979066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115069.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115069.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095797.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095797.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:516536", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516536", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZR28-1", "protein_name": "Protein eva-1 homolog C", "gene_name": "Eva1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLPGHPRLPPGPQPPQNPGLRRQVEPPGQLLRLFYCTVLVCSKETSALTDFSGYLTKLLQNHTAYACDGDYLNLQCPRHSTISVQSAFYGQDFQRCSPQEPISQREDNLTCVASTALQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDQELKLHCHGSKFLNIYSAAYGRRTQQTDICSSGAELLPPFDCLSYTASQVLSRRCYGKQRCKVLVDNYHFGSPCLPGVKKYLTVAYACVPKNILTAVDPAVANLNPSLKKDDEYGIKFNPSGSRVVRKDGVIVSNSLAAFAYIRAHPERAALLFVSSVCIGLFLTLCALVIRVSCTKDFQELRQGREHLVQGSDKAEEDSEEDVEEEDSSDSEFPVELSRFCRTTYPAYSSIEAAELAERIERREQIIQEIWMNSGLDSSLPRNMGHFY", "length": 440 }, "evidence": [ { "id": "A0A3Q1LMN4", "url": "https://omabrowser.org/oma/group/A0A3Q1LMN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LVN6-1", "protein_name": "Protein eva-1 homolog C", "gene_name": "EVA1C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLLPGHARPLPAPQPAQHPGLRRQVEPPGQLLRLFYCTVLVCSKEISALTDFSGYLTKLLQNHTAYACDGDHLNLQCPRHSTISVQSAFYGQDYQMCSTQQPASQREDSLTCMAPTTLQKVLDECQNQRSCHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDHELKLHCHESKYLNIYSATYGRRTQERDVCSSEAGRLPPFDCLSYAAALQVLSRRCYGKQRCKILVNNHHFGSPCLPGVKKYLTVTYACVPKNILTAIDPGVADLKPSSTQKDGDYGIKFDPREPRVLRKDGVIVSHSLAAFAYLRAHPERAALLFVSSVCIGLALTLCALVIRVSCTKDFRELQLAREHLVPGSDKAEEDSQDEEEEEDSSDSDFPGELSGFRRTTYPVYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMSQFY", "length": 442 }, "evidence": [ { "id": "A0A3Q1LMN4", "url": "https://omabrowser.org/oma/group/A0A3Q1LMN4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P58658-1", "protein_name": "Protein eva-1 homolog C", "gene_name": "EVA1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLPGRARQPPTPQPVQHPGLRRQVEPPGQLLRLFYCTVLVCSKEISALTDFSGYLTKLLQNHTTYACDGDYLNLQCPRHSTISVQSAFYGQDYQMCSSQKPASQREDSLTCVAATTFQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCEDQELKLHCHESKFLNIYSATYGRRTQERDICSSKAERLPPFDCLSYSALQVLSRRCYGKQRCKIIVNNHHFGSPCLPGVKKYLTVTYACVPKNILTAIDPAIANLKPSLKQKDGEYGINFDPSGSKVLRKDGILVSNSLAAFAYIRAHPERAALLFVSSVCIGLALTLCALVIRESCAKDFRDLQLGREQLVPGSDKVEEDSEDEEEEEDPSESDFPGELSGFCRTSYPIYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRNMGQFY", "length": 441 }, "evidence": [ { "id": "A0A3Q1LMN4", "url": "https://omabrowser.org/oma/group/A0A3Q1LMN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P58659-1", "protein_name": "Protein eva-1 homolog C", "gene_name": "Eva1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLPGHPRPPPAPQSAQNQGLRRQVEPPGQLLRLFYCTVLVCSKETSALTDFSGYLTKLLQNHTAYACDGDYLNLQCPRHSTISVQSAFYGQDYQMCSSQEPISQREDNLTCVASTTLQKVLDECQNQRACHLLVNSRVFGPDLCPGSSKYLLVSFKCQPNELKNKTVCENQELKLHCHESKFLNIYSAAYGRRTQQRDICSSGAELLPPFDCLSYTALQVLSRRCYGKQRCKVLVDNYHFGSPCLPGVKKYLTVAYACVPKNILTAVDPAVANLNPSLKKDDEHGITFNPSGSRVVRKDGVIVSNSLAAFAYIRAHPERAALLFMSSVCIGLLLTLCALVIRVSCTKDFRELRQGREHLVLGSDKAEEDSEEDLEEEDSSDSQFPEELSRFCRTSYPAYSSIEAAELAERIERREQVIQEIWMNSGLDSSLPRNVGHFY", "length": 440 }, "evidence": [ { "id": "A0A3Q1LMN4", "url": "https://omabrowser.org/oma/group/A0A3Q1LMN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LMN4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 441, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LMN4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMN4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LMN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN4" }, { "id": "PS50228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUEL-type lectin", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 159, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LMP1-1", "uniprot_ac": "A0A3Q1LMP1", "uniprot_id": "A0A3Q1LMP1_BOVIN", "mass": { "chemical_mass": 35353.0, "monoisotopic_mass": 35353.0 }, "refseq": { "ac": "NP_001377303", "name": "olfactory receptor family 5 subfamily H member 36", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377303" }, "gene_names": [ { "name": "OR5H36", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1" } ] }, { "name": "OR5H36", "type": "synonym", "evidence": [ { "id": "NP_001377303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377303" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5H2", "type": "synonym", "evidence": [ { "id": "NP_001377303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377303" } ] }, { "name": "olfactory receptor 5H8", "type": "synonym", "evidence": [ { "id": "NP_001377303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377303" } ] }, { "name": "olfactory receptor family 5 subfamily H member 36", "type": "synonym", "evidence": [ { "id": "NP_001377303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377303" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377303" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5H36", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1", "locus": { "chromosome": "1", "start_pos": 42461380, "end_pos": 42460442, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000054488", "url": "https://www.ensembl.org/id/ENSBTAG00000054488" } ] } } ], "crossref": [ { "id": "A0A3Q1LMP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000054488", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054488", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "783812", "url": "https://www.ncbi.nlm.nih.gov/gene/783812", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:783812", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783812", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAIIHES", "url": "https://omabrowser.org/oma/group/HAIIHES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMP1", "url": "https://www.orthodb.org/?gene=A0A3Q1LMP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METKNATEVREFILTGLTHQPEWQIPLFLLFFMIYLITVMGNTGLIALIYNDPQLHIPMYSFLGNLAFVDTWLSSTVTPKMLVNFLGKSKTISLSECKVQFFSFAISVTTECFLLATMAYDRYAAICKPLLYPVIMTNRLCMQLLVSSFVGGLIHALIHTGFLFRLTFCNSNIILHFYCDVMPLIKISCTDPSINVLMIFIFSGSIQVFTILIVLVSYTLVLFTILKKKSLQGLRKAFSTCGAHLLSVSLYYGPLLFMYVRPGSTQADDQDMMDSLFYTVIIPFLNPIIYSLRNKKVIDSLTKMLKRDGCIS", "length": 312, "header": "tr|A0A3Q1LMP1-1|A0A3Q1LMP1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5H36 PE=3 SV=1 CANONICAL=A0A3Q1LMP1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1/entry", "sequence": { "sequence": "METKNATEVREFILTGLTHQPEWQIPLFLLFFMIYLITVMGNTGLIALIYNDPQLHIPMYSFLGNLAFVDTWLSSTVTPKMLVNFLGKSKTISLSECKVQFFSFAISVTTECFLLATMAYDRYAAICKPLLYPVIMTNRLCMQLLVSSFVGGLIHALIHTGFLFRLTFCNSNIILHFYCDVMPLIKISCTDPSINVLMIFIFSGSIQVFTILIVLVSYTLVLFTILKKKSLQGLRKAFSTCGAHLLSVSLYYGPLLFMYVRPGSTQADDQDMMDSLFYTVIIPFLNPIIYSLRNKKVIDSLTKMLKRDGCIS", "length": 312, "header": "tr|A0A3Q1LMP1-1|A0A3Q1LMP1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5H36 PE=3 SV=1 CANONICAL=A0A3Q1LMP1-1" }, "locus": { "chromosome": "1", "start_pos": 42461377, "end_pos": 42460442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069256.1", "url": "https://www.ensembl.org/id/ENSBTAT00000069256.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057988.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057988.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783812", "name": "", "url": 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"UniProtKB", "id": "A0A3Q1LMP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LMP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LMP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMP1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LMP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LMR9-1", "uniprot_ac": "A0A3Q1LMR9", "uniprot_id": "A0A3Q1LMR9_BOVIN", "mass": { "chemical_mass": 15190.0, "monoisotopic_mass": 15190.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Core Histone H2A/H2B/H3 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMR9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMR9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMR9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMR9", "locus": {} } ], "crossref": [ { "id": "A0A3Q1LMR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047659", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047659", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22911", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22911", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ARKSAPX", "url": "https://omabrowser.org/oma/group/ARKSAPX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11426", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11426", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LMR9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQAATKATRKSAPSTGGVKKPHRYRPGTVALHEIRCYQKSTELLIRKLPFQRLVREIAQDFKTDLCFQSAAIGALQEASEAYLVGLFENTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136, "header": "tr|A0A3Q1LMR9-1|A0A3Q1LMR9_BOVIN Isoform 1 of Core Histone H2A/H2B/H3 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0A3Q1LMR9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMR9/entry", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQAATKATRKSAPSTGGVKKPHRYRPGTVALHEIRCYQKSTELLIRKLPFQRLVREIAQDFKTDLCFQSAAIGALQEASEAYLVGLFENTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136, "header": "tr|A0A3Q1LMR9-1|A0A3Q1LMR9_BOVIN Isoform 1 of Core Histone H2A/H2B/H3 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0A3Q1LMR9-1" }, "locus": { "chromosome": "11", "start_pos": 2422994, "end_pos": 2422587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080694.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080694.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061196.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061196.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": 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"Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03210", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03210", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KKSCVFG", "url": "https://omabrowser.org/oma/group/KKSCVFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMV5", "url": "https://www.orthodb.org/?gene=A0A3Q1LMV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571:SF255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11571:SF255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14497", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3299685", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3299685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPYTIVYFPVQGRCEAMRMLLADQGQSWKEEVVAMQSWLQGPLKASCLYGQLPKFQDGDLTLYQSNAILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYVSLIYTNYEAGKEDYVKALPQHLKPFETLLSQNKGGQAFIVGDQISFADYNLLDLLRIHQVLAPSCLDSFPLLSAYVARLNSRPKLKAFLASPGAHEPAHQRQWETVRACGTLCARQGAACSSLSPGPIKLPREKQ", "length": 240, "header": "tr|A0A3Q1LMV5-1|A0A3Q1LMV5_BOVIN Isoform 1 of Glutathione S-transferase OS=Bos taurus OX=9913 GN=LOC281806 PE=3 SV=1 CANONICAL=A0A3Q1LMV5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5/entry", "sequence": { "sequence": "MPPYTIVYFPVQGRCEAMRMLLADQGQSWKEEVVAMQSWLQGPLKASCLYGQLPKFQDGDLTLYQSNAILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYVSLIYTNYEAGKEDYVKALPQHLKPFETLLSQNKGGQAFIVGDQISFADYNLLDLLRIHQVLAPSCLDSFPLLSAYVARLNSRPKLKAFLASPGAHEPAHQRQWETVRACGTLCARQGAACSSLSPGPIKLPREKQ", "length": 240, "header": "tr|A0A3Q1LMV5-1|A0A3Q1LMV5_BOVIN Isoform 1 of Glutathione S-transferase OS=Bos taurus OX=9913 GN=LOC281806 PE=3 SV=1 CANONICAL=A0A3Q1LMV5-1" }, "locus": { "chromosome": "29", "start_pos": 45444792, "end_pos": 45441989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084460.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084460.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061249.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061249.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156590", "resource": "Reactome", "description": "Glutathione conjugation" }, { "id": "R-BTA-3299685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3299685", "resource": "Reactome", "description": "Detoxification of Reactive Oxygen Species" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "P04906-1", "protein_name": "Glutathione S-transferase P", "gene_name": "Gstp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPYTIVYFPVRGRCEATRMLLADQGQSWKEEVVTIDVWLQGSLKSTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKDQKEAALVDMVNDGVEDLRCKYGTLIYTNYENGKDDYVKALPGHLKPFETLLSQNQGGKAFIVGNQISFADYNLLDLLLVHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPDHLNRPINGNGKQ", "length": 210 }, "evidence": [ { "id": "A0A3Q1LMV5", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P09211-1", "protein_name": "Glutathione S-transferase P", "gene_name": "GSTP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ", "length": 210 }, "evidence": [ { "id": "A0A3Q1LMV5", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19157-1", "protein_name": "Glutathione S-transferase P 1", "gene_name": "Gstp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPEHVNRPINGNGKQ", "length": 210 }, "evidence": [ { "id": "A0A3Q1LMV5", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q556G3-1", "protein_name": "Putative glutathione S-transferase alpha-2", "gene_name": "gsta2-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTSSVPSLTYFQGRGLGQFSRVLLSYLGIPYENITVTEISDALRATLPYGQLPIYRDGDFVLTQSSTIARYIAKKHNFMGKNLEEEFLVDQIVTAIHADIFPAFNNPVPEKLQKLYEKYFGSFEKKLQETGFLVGSSVTLADLYVYVGFDYIRFRGEAALSSELSDEKYPKIAELKKFFESNEGVAKYIKERPETKF", "length": 198 }, "evidence": [ { "id": "A0A3Q1LMV5", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18879-1", "F1MUX5-1", "F1MX44-1", "A0ABI0P5M0-1", "A0AAA9TW47-1", "F6QEM8-1", "A0ABI0P3R2-1", "A0AAF6Z0W3-1", "P28801-1", "Q2KJG4-1", "A0A3Q1LMV5-1", "F1MVX2-1", "Q28035-1", "Q9N0V4-1", "Q2NL00-1", "F1MXY2-1", "E1BED9-1", "A0ABI0P006-1", "Q5E9G0-1", "Q64L89-1", "A0A452DIU1-1", "F1MGZ9-1", "A0AAA9TXU3-1", "E1BJX2-1" ], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "R-BTA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18879-1", "E1BED9-1", "A0ABI0P006-1", "A0ABI0P5M0-1", "A0A3Q1LMV5-1", "F1MGZ9-1", "F1MUX5-1", "F1MX44-1", "Q2NL00-1", "Q5E9G0-1", "A0A452DIU1-1" ], "evidence": [ { "id": "R-BTA-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176054" } ] }, { "id": "R-BTA-3343700", "name": "PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O77834-1", "A0A3Q1LMV5-1" ], "evidence": [ { "id": "R-BTA-3343700", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3343700" } ] }, { "id": "R-BTA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19120-1", "P68401-1", "A0JNA3-1", "F1MMD5-1", "A0AAA9S4U4-1", "P80177-1", "Q0II59-1", "Q0VCM4-1", "Q3SWY3-1", "Q3SYU2-1", "F1MHT1-1", "A0AAA9RV00-1", "A0ABI0P3F2-1", "P62935-1", "P68103-1", "Q3T0Q4-1", "A0A452DJA8-1", "E1BNY9-1", "A0A3Q1LMV5-1", "A0A3Q1LTT9-1", "A1A4J1-1", "F1MQ78-1", "G3X757-1", "P00432-1", "Q76LV2-1", "A0A140T8A5-1", "A0A3Q1LR63-1", "Q56JW4-1", "Q3T0A3-1", "Q3ZBD7-1", "Q58DK5-1", "Q3SZ62-1", "Q3T0V9-1", "Q3ZCI9-1" ], "evidence": [ { "id": "R-BTA-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798748" } ] }, { "id": "R-BTA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19120-1", "P68401-1", "P80227-1", "A0JNA3-1", "F1MMD5-1", "Q32PF2-1", "Q3SZH7-1", "A0AAA9S4U4-1", "A0AAA9S9V5-1", "P07688-1", "O46414-1", "P25326-1", "P80177-1", "Q0VCM4-1", "Q3SWY3-1", "Q3SYU2-1", "F1MHT1-1", "F1MMR6-1", "A0ABI0NJH4-1", "A0AAA9RV00-1", "A0ABI0P3F2-1", "P05689-1", "P46196-1", "P52176-1", "P62935-1", "P68103-1", "Q17QB3-1", "Q3T0Q4-1", "Q27970-1", "A0A452DJA8-1", "E1BNY9-1", "A0A3Q1LMV5-1", "A0A3Q1LTT9-1", "A0AAA9SYX5-1", "A1A4J1-1", "E1BB52-1", "F1MQ78-1", "G3X757-1", "P00432-1", "Q76LV2-1", "A0A140T8A5-1", "A0A3Q1LR63-1", "A0A3Q1NDQ7-1", "Q3T0A3-1", "Q3ZBD7-1", "Q58DK5-1", "Q3SZ62-1", "Q3T0V9-1", "Q3ZCI9-1" ], "evidence": [ { "id": "R-BTA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6800434" } ] }, { "id": "R-BTA-9753280", "name": "GSTs transfer GSH to NAPQI to form APAP-SG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9753466" ], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LMV5-1", "Q2NL00-1" ], "evidence": [ { "id": "R-BTA-9753280", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9753280" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-9753466", "participant_name": "NAPQI [cytosol]", "crossref": [ { "id": "173517", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8A5", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] } ] }, { "uniprot_ac": "A0A3Q1LMV5", "gene_name": "LOC281806", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] } ] }, { "uniprot_ac": "A0A3Q1LR63", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR63" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR63" } ] } ] }, { "uniprot_ac": "A0A3Q1LTT9", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTT9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LTT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTT9" } ] } ] }, { "uniprot_ac": "A0A3Q1NDQ7", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A3Q1NDQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDQ7" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1NDQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDQ7" } ] } ] }, { "uniprot_ac": "A0A452DIU1", "gene_name": "LOC327709", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A452DIU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DIU1" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A452DIU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DIU1" } ] } ] }, { "uniprot_ac": "A0A452DJA8", "gene_name": "PNP", "activity": [ { "ec_number": "2.4.2.1", "activity": "adenosine + phosphate = alpha-D-ribose 1-phosphate + adenine.", "evidence": [ { "id": "A0A452DJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA8" } ] }, { "ec_number": "2.4.2.1", "activity": "", "evidence": [ { "id": "A0A452DJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA8" } ] } ] }, { "uniprot_ac": "A0AAA9RV00", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] } ] }, { "uniprot_ac": "A0AAA9S4U4", "gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0AAA9S4U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4U4" } ] } ] }, { "uniprot_ac": "A0AAA9S9V5", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0AAA9S9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9V5" } ] } ] }, { "uniprot_ac": "A0AAA9SYX5", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9SYX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYX5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9SYX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYX5" } ] } ] }, { "uniprot_ac": "A0AAA9TW47", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] } ] }, { "uniprot_ac": "A0AAA9TXU3", "gene_name": "GSTZ1", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "5.2.1.2", "activity": "", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] } ] }, { "uniprot_ac": "A0AAF6Z0W3", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAF6Z0W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0W3" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAF6Z0W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0W3" } ] } ] }, { "uniprot_ac": "A0ABI0NJH4", "gene_name": "GNS", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "A0ABI0NJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJH4" } ] } ] }, { "uniprot_ac": "A0ABI0P006", "gene_name": "LOC785216", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P3R2", "gene_name": "GSTT2", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "4.1.1.84", "activity": "D-dopachrome + H(+) = 5,6-dihydroxyindole + CO2.", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "4.1.1.84", "activity": "", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] } ] }, { "uniprot_ac": "A0ABI0P5M0", "gene_name": "GSTA1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P5M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M0" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P5M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M0" } ] } ] }, { "uniprot_ac": "A0JNA3", "gene_name": "IMPDH1", "activity": [ { "ec_number": "1.1.1.205", "activity": "IMP + NAD(+) + H2O = XMP + NADH + H(+).", "evidence": [ { "id": "A0JNA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNA3" } ] }, { "ec_number": "1.1.1.205", "activity": "", "evidence": [ { "id": "A0JNA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNA3" } ] } ] }, { "uniprot_ac": "A1A4J1", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A1A4J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4J1" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A1A4J1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4J1" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BED9", "gene_name": "GSTO2", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] } ] }, { "uniprot_ac": "E1BJX2", "gene_name": "GSTT4", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BJX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BJX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX2" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MGZ9", "gene_name": "HPGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "5.3.99.2", "activity": "", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] } ] }, { "uniprot_ac": "F1MHT1", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMR6", "gene_name": "CTSD", "activity": [ { "ec_number": "3.4.23.5", "activity": "Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] } ] }, { "uniprot_ac": "F1MQ78", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.12", "activity": "(9Z,12Z,15Z)-octadecatrienoate + O2 = (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate.", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.12", "activity": "", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] } ] }, { "uniprot_ac": "F1MUX5", "gene_name": "LOC100295687", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MUX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUX5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MUX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUX5" } ] } ] }, { "uniprot_ac": "F1MVX2", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MVX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVX2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MVX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVX2" } ] } ] }, { "uniprot_ac": "F1MX44", "gene_name": "GSTA5", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX44" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX44" } ] } ] }, { "uniprot_ac": "F1MXY2", "gene_name": "MGST1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MXY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXY2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MXY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXY2" } ] } ] }, { "uniprot_ac": "F6QEM8", "gene_name": "LOC783879", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F6QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QEM8" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F6QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QEM8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18879", "gene_name": "GSTA2", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "O18879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18879" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "O18879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18879" } ] } ] }, { "uniprot_ac": "O46414", "gene_name": "FTH1", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] } ] }, { "uniprot_ac": "O77834", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] } ] }, { "uniprot_ac": "P00432", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] } ] }, { "uniprot_ac": "P05689", "gene_name": "CTSZ", "activity": [ { "ec_number": "3.4.18.1", "activity": "Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] }, { "ec_number": "3.4.18.1", "activity": "", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] } ] }, { "uniprot_ac": "P07688", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "P07688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07688" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "P07688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07688" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P25326", "gene_name": "CTSS", "activity": [ { "ec_number": "3.4.22.27", "activity": "Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] }, { "ec_number": "3.4.22.27", "activity": "", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] } ] }, { "uniprot_ac": "P28801", "gene_name": "GSTP1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "P28801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28801" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "P28801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28801" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P52176", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] } ] }, { "uniprot_ac": "P62935", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P62935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62935" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P62935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62935" } ] } ] }, { "uniprot_ac": "P68103", "gene_name": "EEF1A1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P68103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68103" } ] } ] }, { "uniprot_ac": "P68401", "gene_name": "PAFAH1B2P68402", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "P68401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68401" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "P68401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68401" } ] } ] }, { "uniprot_ac": "P80177", "gene_name": "MIF", "activity": [ { "ec_number": "5.3.2.1", "activity": "3-phenylpyruvate = enol-phenylpyruvate.", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] }, { "ec_number": "5.3.3.12", "activity": "L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] }, { "ec_number": "5.3.2.1", "activity": "", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] }, { "ec_number": "5.3.3.12", "activity": "", "evidence": [ { "id": "P80177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80177" } ] } ] }, { "uniprot_ac": "P80227", "gene_name": "APEH", "activity": [ { "ec_number": "3.4.19.1", "activity": "Internal cleavage of oxidized and glycated proteins.", "evidence": [ { "id": "P80227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80227" } ] }, { "ec_number": "3.4.19.1", "activity": "", "evidence": [ { "id": "P80227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P80227" } ] } ] }, { "uniprot_ac": "Q0II59", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "Q0II59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II59" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "Q0II59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II59" } ] } ] }, { "uniprot_ac": "Q0VCM4", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "Q0VCM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCM4" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "Q0VCM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCM4" } ] } ] }, { "uniprot_ac": "Q17QB3", "gene_name": "ASAH1", "activity": [ { "ec_number": "3.5.1.23", "activity": "an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid.", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] }, { "ec_number": "3.5.1.23", "activity": "", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] }, { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "Q17QB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QB3" } ] } ] }, { "uniprot_ac": "Q27970", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "Q27970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27970" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "Q27970", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27970" } ] } ] }, { "uniprot_ac": "Q28035", "gene_name": "GSTA1", "activity": [ { "ec_number": "1.11.1.-", "activity": "", "evidence": [ { "id": "Q28035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28035" } ] }, { "ec_number": "5.3.3.-", "activity": "", "evidence": [ { "id": "Q28035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28035" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q28035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28035" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q28035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28035" } ] } ] }, { "uniprot_ac": "Q2KJG4", "gene_name": "MGST2", "activity": [ { "ec_number": "1.11.1.-", "activity": "", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] }, { "ec_number": "4.4.1.20", "activity": "leukotriene C4 = leukotriene A4 + glutathione.", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] }, { "ec_number": "4.4.1.20", "activity": "", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] } ] }, { "uniprot_ac": "Q2NL00", "gene_name": "GSTT1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q2NL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL00" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q2NL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL00" } ] } ] }, { "uniprot_ac": "Q32PF2", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "Q32PF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PF2" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "Q32PF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PF2" } ] } ] }, { "uniprot_ac": "Q3SWY3", "gene_name": "IMPDH2", "activity": [ { "ec_number": "1.1.1.205", "activity": "IMP + NAD(+) + H2O = XMP + NADH + H(+).", "evidence": [ { "id": "Q3SWY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY3" } ] }, { "ec_number": "1.1.1.205", "activity": "", "evidence": [ { "id": "Q3SWY3", 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Classification" ] }, { "id": "IPR019809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:107131556", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131556", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMV7", "url": "https://www.orthodb.org/?gene=A0A3Q1LMV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015314533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVNALKRQGRTLYGFGG", "length": 103, "header": "tr|A0A3Q1LMV7-1|A0A3Q1LMV7_BOVIN Isoform 1 of Histone H4 OS=Bos taurus OX=9913 GN=LOC107131556 PE=3 SV=1 CANONICAL=A0A3Q1LMV7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7/entry", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVNALKRQGRTLYGFGG", "length": 103, "header": "tr|A0A3Q1LMV7-1|A0A3Q1LMV7_BOVIN Isoform 1 of Histone H4 OS=Bos taurus OX=9913 GN=LOC107131556 PE=3 SV=1 CANONICAL=A0A3Q1LMV7-1" }, "locus": { "chromosome": "20", "start_pos": 9296890, "end_pos": 9296582, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085055.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085055.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058253.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058253.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:107131556", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131556", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LMV7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 103, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LMV7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LMV7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV7" }, { "id": "SM00803", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00803" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TATA box binding protein associated factor (TAF) histone-like fold", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 93, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LMV9-1", "uniprot_ac": "A0A3Q1LMV9", "uniprot_id": "A0A3Q1LMV9_BOVIN", "mass": { "chemical_mass": 375667.0, "monoisotopic_mass": 375667.0 }, "refseq": {}, "gene_names": [ { "name": "EPPK1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ] } ], "protein_names": [ { "name": "Epiplakin", "type": "recommended", "evidence": [ { "id": "A0A3Q1LMV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress. In response to mechanical stress like wound healing, is associated with the machinery for cellular motility by slowing down keratinocyte migration and proliferation and accelerating keratin bundling in proliferating keratinocytes thus contributing to tissue architecture. However in wound healing in corneal epithelium also positively regulates cell differentiation and proliferation and negatively regulates migration thereby controlling corneal epithelium morphogenesis and integrity. In response to cellular stress, plays a role in keratin filament reorganization, probably by protecting keratin filaments against disruption. During liver and pancreas injuries, plays a protective role by chaperoning disease-induced intermediate filament reorganization.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9#function" }, { "database": "UniProtKB", "id": "ARBA00053437", "url": "https://www.uniprot.org/uniprotkb/ARBA00053437#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EPPK1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9", "locus": { "chromosome": "14", "start_pos": 955681, "end_pos": 940689, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045727", "url": "https://www.ensembl.org/id/ENSBTAG00000045727" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045727", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045727", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CEAKSKG", "url": "https://omabrowser.org/oma/group/CEAKSKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23169:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23169:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGHAFPLDLLVTGGTGPTAVSKTMKAALGAGAPSAPQARSIAGVWVEASGRAQGLYAAMKQGLLPSGLGLALLEAQAATGGLVDPTQGQLLPVSEALQQGLVGLELKEKLLAAERAATGYPDPYGGQKLALFQAIGKEVVDRALGWNWLEAQLATGGLVDPIRGVRVAPELACQQGLLDQETWHGLSELGPGSSAPGFLDPNTLEQLPYRELLARCVQAPGTGLALLPLRITFHTLGGAVSLAELLEVGVLDEETARGLREGRLVVPDVGARAEVRRYLQGTGSVAGVVLLPAGHKKSFFQAAAEHLLPTGAMLLLLEAQAATCSLVDPATGRQLRVDEAVRAGLVGPELHRQLQVAEQAVTGYHDPFSGTRVPLFQAMKKELVDQPLALRLLDAQLATGGLVCPARRLRLPVEAALRLGCLDKETQEHLSRAASFLDPGTHESLSYGQLLARCITDLETGLAFLPISVGSPGEEPRGPPFIEHSTRQVLSAATATVSVGRFQGRPVSLWELLFSKAVPMEQRVTLTQQHRDGALSVEELAAVLRATHEQAAATARTTFAGLRVPVTPGELLRAEIIGQDVYEQLERGQTTAQDVANLDSVQRYLQGTGCIAGLLLPGSQEPLSIHEAYRKGLLRPGTALILLEAQAATGFIIDPKENRRYSVEEALRAGIIGPEVFAKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEALNLILADPSDDTKGFFDPNTHENLTYMQLLERCVRDPNTGLYLLPLTSARTLLADEATRQAFRSLLLSVQHGRFRGQRVSAWELVNSEYVSEARRRWLLQSFRRHQVSLEEVSKLLEREVESRADVALPMLRGRVTACQLREAGVIDQEVLDCVLAGTLSAEALLCTESIRRFLCGSGAVGGVLLQPSTRRLSLYQAMKHKLLGPGVALALLEAQAATGTMTDPHSLETMSLDEAVCRGLVGPELYSRLTWAECAVKGFPDPFSGKLLSLFQAMKKGLVPMEQAIRLLEAQVATGGVIDPTGHHHLPMLVALQRGYIDQEMVLALSDSKTFPTPDGQGHTSYAQLLEQCVKDEASGLHFLPLPESAPVVPTDEQVQETLKATQGAEDGTSLWELLESCHFTEEQRRGFLEDFREGRTTTQQLQAAVRRQVQEAELLAGACVMLPGPCGGVPAVWLLDAGVITRETLEALARGMQSPAEVAEQPTVRACLWGTGCVAGVLLQPSGAKVSIAQAVRDGLLPAGLGQRLLEAQVASGSLVDPLTNQRLSVEEAVKAGLVAGALSERLQLVEKAVAGYTDPCSGGSLSLWQAVEKGLVPWSEGLPLLQAQLATGGVVDPVHRVHLPQAAACRLGLLDEQTSRMLTSMDEDSKFFFDPGTQDKVTYGQLKERCVLDADTGLWLLPLSQDMVLEVDDHTAVALRAMKVPVGAGRFRGLNISLWDLLHSEYVGLRKRRELAALCQSGRATALRQVVTAVTTLVEASERQPSQATFRGLRKQLSANDLFRSQLIDRKTLDELSQGKKTVQEVAEMDRVRRYLEGGSFIAGVLIQDTREKMSISEALRRNVLRPGTALVLLEAQAATGFLIDPVENRKLTVQEAFAAGMFGRETYQKLLSAERAVTGYTDPYTGEQISLFQAMKKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYMQLLERCVEDPETGLYMLQVVKKGETYVYIDEATRQALRSKTTKMHVGMFAQQVVSFWDLLSSPYFTEERKKELVQGYKARDVSLEQLLKVITTTVEETEQRNKGIRLAAIGGEVTAAELFNSGIIDKKTLDALHEGTGGQDLRRLPHVKVYLEGSGCIAGLTTPSTREVLSFYEASRKGLIPMGFAAQLLEAQAATGFLLDPHSHKRLSVDEAVAAGLVGEEMQERLLNAEKAARGYTDPDTGHTMSLFQAMQRKLVKRELALRLLEVQMATGGIVDPQHHHRLPLDAAYRRGCLDQDTYPLVAEQKCMNKRFVDPNTQEKVTYQELQERSRRDEKTGWALFPVLEHELESQFIDEDTRRALEAERVDVRVGRFKGQRPSVWELLNSEYVTENKKLELVRKYKTDTAHALEKVVKVIFEIISEKEKNTKQLWFRGIRKQITASELLTSSIITKETLQALESGQASVDAITKTEGVRRYLEGTGCIAGVLVPAKDEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNQKLSVEEAVAAGVVGGELQEKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYVQLLRRCVRDPDTGLYMLQLAGRGSALHQLGEELRAALRDTRVTLGAGPPRGQRVSVWELLFYREVSESQRQDLLRRYRAGSLTAQEVGAALVSLLAEAEAEAARPGAPDPRGALRAATMEVRVGRLRGPAVPVWDVLASGYVSAATREQLLAEFGAGTLGLPALTRRLTTIIEEAEAAPSQGGGASGQREPGPQGPGEGADAGPSSGQDAEDAARALQEQALRAATMEVRVGRFQGRRVSVWEVLFSSYLSQARRDELLAQHAAGALALPALVAVLTQLIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNQKLSVEEAVAAGVVGGELQEKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYVQLLRRCVRDPDTGLYMLQLAGRGSALHQLGEELRAALRDTRVTLGAGPPRGQRVSVWELLFYREVSESQRQDLLRRYRAGSLTAQEVGAALVSLLAEAEAEAARPGAPDPRGALRAATMEVRVGRLRGPAVPVWDVLASGYVSAATREQLLAEFGAGTLGLPALTRRLTTIIEEAEAAPSQGGGASGQREPGPQGPGEGADAGPSSGQDAEDAARALQEQALRAATMEVRVGRFQGRRVSVWEVLFSSYLSQARRDELLAQHAAGALALPALVAVLTQLIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNQKLSVEEAVAAGVVGGELQEKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYVQLLQRATRDPETGLLFLSLTV", "length": 3449, "header": "tr|A0A3Q1LMV9-1|A0A3Q1LMV9_BOVIN Isoform 1 of Epiplakin OS=Bos taurus OX=9913 GN=EPPK1 PE=1 SV=2 CANONICAL=A0A3Q1LMV9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9/entry", "sequence": { "sequence": "MNGHAFPLDLLVTGGTGPTAVSKTMKAALGAGAPSAPQARSIAGVWVEASGRAQGLYAAMKQGLLPSGLGLALLEAQAATGGLVDPTQGQLLPVSEALQQGLVGLELKEKLLAAERAATGYPDPYGGQKLALFQAIGKEVVDRALGWNWLEAQLATGGLVDPIRGVRVAPELACQQGLLDQETWHGLSELGPGSSAPGFLDPNTLEQLPYRELLARCVQAPGTGLALLPLRITFHTLGGAVSLAELLEVGVLDEETARGLREGRLVVPDVGARAEVRRYLQGTGSVAGVVLLPAGHKKSFFQAAAEHLLPTGAMLLLLEAQAATCSLVDPATGRQLRVDEAVRAGLVGPELHRQLQVAEQAVTGYHDPFSGTRVPLFQAMKKELVDQPLALRLLDAQLATGGLVCPARRLRLPVEAALRLGCLDKETQEHLSRAASFLDPGTHESLSYGQLLARCITDLETGLAFLPISVGSPGEEPRGPPFIEHSTRQVLSAATATVSVGRFQGRPVSLWELLFSKAVPMEQRVTLTQQHRDGALSVEELAAVLRATHEQAAATARTTFAGLRVPVTPGELLRAEIIGQDVYEQLERGQTTAQDVANLDSVQRYLQGTGCIAGLLLPGSQEPLSIHEAYRKGLLRPGTALILLEAQAATGFIIDPKENRRYSVEEALRAGIIGPEVFAKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEALNLILADPSDDTKGFFDPNTHENLTYMQLLERCVRDPNTGLYLLPLTSARTLLADEATRQAFRSLLLSVQHGRFRGQRVSAWELVNSEYVSEARRRWLLQSFRRHQVSLEEVSKLLEREVESRADVALPMLRGRVTACQLREAGVIDQEVLDCVLAGTLSAEALLCTESIRRFLCGSGAVGGVLLQPSTRRLSLYQAMKHKLLGPGVALALLEAQAATGTMTDPHSLETMSLDEAVCRGLVGPELYSRLTWAECAVKGFPDPFSGKLLSLFQAMKKGLVPMEQAIRLLEAQVATGGVIDPTGHHHLPMLVALQRGYIDQEMVLALSDSKTFPTPDGQGHTSYAQLLEQCVKDEASGLHFLPLPESAPVVPTDEQVQETLKATQGAEDGTSLWELLESCHFTEEQRRGFLEDFREGRTTTQQLQAAVRRQVQEAELLAGACVMLPGPCGGVPAVWLLDAGVITRETLEALARGMQSPAEVAEQPTVRACLWGTGCVAGVLLQPSGAKVSIAQAVRDGLLPAGLGQRLLEAQVASGSLVDPLTNQRLSVEEAVKAGLVAGALSERLQLVEKAVAGYTDPCSGGSLSLWQAVEKGLVPWSEGLPLLQAQLATGGVVDPVHRVHLPQAAACRLGLLDEQTSRMLTSMDEDSKFFFDPGTQDKVTYGQLKERCVLDADTGLWLLPLSQDMVLEVDDHTAVALRAMKVPVGAGRFRGLNISLWDLLHSEYVGLRKRRELAALCQSGRATALRQVVTAVTTLVEASERQPSQATFRGLRKQLSANDLFRSQLIDRKTLDELSQGKKTVQEVAEMDRVRRYLEGGSFIAGVLIQDTREKMSISEALRRNVLRPGTALVLLEAQAATGFLIDPVENRKLTVQEAFAAGMFGRETYQKLLSAERAVTGYTDPYTGEQISLFQAMKKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYMQLLERCVEDPETGLYMLQVVKKGETYVYIDEATRQALRSKTTKMHVGMFAQQVVSFWDLLSSPYFTEERKKELVQGYKARDVSLEQLLKVITTTVEETEQRNKGIRLAAIGGEVTAAELFNSGIIDKKTLDALHEGTGGQDLRRLPHVKVYLEGSGCIAGLTTPSTREVLSFYEASRKGLIPMGFAAQLLEAQAATGFLLDPHSHKRLSVDEAVAAGLVGEEMQERLLNAEKAARGYTDPDTGHTMSLFQAMQRKLVKRELALRLLEVQMATGGIVDPQHHHRLPLDAAYRRGCLDQDTYPLVAEQKCMNKRFVDPNTQEKVTYQELQERSRRDEKTGWALFPVLEHELESQFIDEDTRRALEAERVDVRVGRFKGQRPSVWELLNSEYVTENKKLELVRKYKTDTAHALEKVVKVIFEIISEKEKNTKQLWFRGIRKQITASELLTSSIITKETLQALESGQASVDAITKTEGVRRYLEGTGCIAGVLVPAKDEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNQKLSVEEAVAAGVVGGELQEKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYVQLLRRCVRDPDTGLYMLQLAGRGSALHQLGEELRAALRDTRVTLGAGPPRGQRVSVWELLFYREVSESQRQDLLRRYRAGSLTAQEVGAALVSLLAEAEAEAARPGAPDPRGALRAATMEVRVGRLRGPAVPVWDVLASGYVSAATREQLLAEFGAGTLGLPALTRRLTTIIEEAEAAPSQGGGASGQREPGPQGPGEGADAGPSSGQDAEDAARALQEQALRAATMEVRVGRFQGRRVSVWEVLFSSYLSQARRDELLAQHAAGALALPALVAVLTQLIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNQKLSVEEAVAAGVVGGELQEKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYVQLLRRCVRDPDTGLYMLQLAGRGSALHQLGEELRAALRDTRVTLGAGPPRGQRVSVWELLFYREVSESQRQDLLRRYRAGSLTAQEVGAALVSLLAEAEAEAARPGAPDPRGALRAATMEVRVGRLRGPAVPVWDVLASGYVSAATREQLLAEFGAGTLGLPALTRRLTTIIEEAEAAPSQGGGASGQREPGPQGPGEGADAGPSSGQDAEDAARALQEQALRAATMEVRVGRFQGRRVSVWEVLFSSYLSQARRDELLAQHAAGALALPALVAVLTQLIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNQKLSVEEAVAAGVVGGELQEKLLSAERAVTGYTDPYTGQQISLFQAMKKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEEMNRVLEDPSDDTKGFFDPNTHENLTYVQLLQRATRDPETGLLFLSLTV", "length": 3449, "header": "tr|A0A3Q1LMV9-1|A0A3Q1LMV9_BOVIN Isoform 1 of Epiplakin OS=Bos taurus OX=9913 GN=EPPK1 PE=1 SV=2 CANONICAL=A0A3Q1LMV9-1" }, "locus": { "chromosome": "14", "start_pos": 955678, "end_pos": 940689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065585.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065585.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058073.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058073.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1123, "start_aa": "Thr", "end_pos": 1123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1123", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 568, "start_aa": "Thr", "end_pos": 568, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr568", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 87, "start_aa": "Thr", "end_pos": 87, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr87", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AHY5-1", "protein_name": "Epiplakin", "gene_name": "Eppk1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGQAPPHDVVVANGTEKLIVPKIMKNQSEASTPSRPQAKAALPTTARSIAGVYVEASGQTLSIYDAMKQGLLPTGLGVTLLEAQAATGGLMDLAQGQLLPVSEALRRGLVGLELKEKLLAAERAVTGYPDPYGGEKLSLFQAIRKEVVDKTLGWRLLEAQLATGGLVDPTQGVQVAPELACQQGLLDKETWLSLMESEPSMGTLGFSDPNTLEQLPYSVLLGRCVLDPSSGLPLLPLKTTFHTLAGAASAAMLLEAGVLNEETVRGLQEGTLVVSDVGTRPEVQRYLEGTGGLAGVVLLPGGHKKSFFQATVEHSLSKGIALQLLEAQAATRTLVHPSTGQRLWVEEAVKTGLVGPDLHEQLLVAEQAVTGYYDPFSSSRIPLFQAMKKGLVDQPLALRLLDAQVATGGLICPARRFRLPLEAALRFGCLDEETRQRLSQTMGFSDPTTHDRLHYEQLLALSVTDPETGLAFLPLLGMSHANEPQGLPFIDHCTRHVLSKATTSVSVGRYQGRPVSLWELLFSEAVPVKQRAMLAQKHQNGALSVEALAAELKSIVQQAAATAKVTFAGLRDTVTPGELLKAEIINQDLFEQLERGQTSARDVGSLDSVQRYLQGTGCIAGLLLPDSQERLRIYEARSKGLLRPGTALILLEAQAATGFIIDPKENKRYSVEEALRAGVIGLDVYAKLLSAERAVTGYTDPYSGEQISLFQAMQRELIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDQMLNSILLDPSDDTKGFFDPNTHENLTYLQLLERCIHDSETGLHLLPLSGTRPQLVDSSTRQAFQNLLISVKYGRFRGQRVSAWELINSEYFKEDWRRQLLRRCQQRKITLEQVTQLLEKEMRRWADVTLPALQGQVTAYQLLEAHIINQELLDQVLTGTVSPDALLHMSDVRRYLQGSGTVGGVLLQPSNQRISLYQAMKQKLLAPSVALALLEAQAATGAITDPCSMQTLSVDEAVCRGVVGAEVYHKLKQAEHSITGYRDPFSGKTVSLFGAMKKGLVPVEQATRLLEAQVSTGGVVDPTTHLHLPMSVAVQRGCIDQEMEVALSRSPETFPTPDGRGHASYAQLLEQCLQDEPSGLHLLPLTEDAPSVPTDTQIQESLQALAGTEDGLSLWDSLTSCHFTEEQRNGFLEDVRVGKTSVSQLQDIVRSWVQTAKLLARARITVPGPQGEVPAVWLRDAGIITQETLEALAQGVQSPDEVAEQPAVKACLWGTGCVAGVLLQPSGTKLSIAQAVRDGLLPAGLGQQLLEAQVASGFLVNPLTNQRLSVHDAVKAGLVGVELSEQLRQVERAVTGYSDPFSGGLLSLWQAKEKGLVSQSEAFPLLQVQLATGGVVDPVHRVHLPQAVAYKLGLLDEQTSQALTATGEENKLFFDPNSREKVTYQQLKELCVLDADTGLWLLPLPQDTVLEVDDHTAVALRAMKVPINMGRFQGHSVSLWDLLHSEYVGAEKRRELVALCCSGRAAALRQVISMVTTLVEAAEKQPPQATFKGLRKQVSAGDLFRSQLITKQTLDELNQGKRTVEEVTEMDSVRRSLEGGNFIAGVLIRDTKEKMSIPEALRRHILRPGTALVLLEAQAATGFIIDPVENRKLTVEQAFQAGMFGKETYTKLLSAERAVTGYTDPYTGEQISLFQAMQRDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFNEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYMLEIVKKGEIYVYIDEATRQVLRSRTMKMHIGKFAGQTVSVWDLLSSQYFTEGRKRKLLREYRAQNIGLEKLLEVITSTVEDTEKQSQIFKVPGIHGDVTAVELFNSGILDKRTLDALHSGERGRQDLCQLEHIKIYLEGTNCIAGVTAPLTQKVMSFYKASKEELIPAGFAAQLLEAQAATGYLMDPCSRRRLCVDEAIAAGLVGEDLRERLVSAEKAAKGYEDPATGETLPLFQAMEKKLVGREEALRLLEVQVATGGVIDPLHRHRIPLDVACQRGCLCEDIIVLIADQKHMRRRFVDPNTQEKVTYQELQDRCRKEEKSGWALFPVVKDKKDMDYVDEATKRALEAEQVEVTVGRYRGQKPSVWELLNSEYFSEEKKIELVRIYKEDTARALQKVVKLILKIIADKEGRSRQLWFRGLRTQVTAEELLRAAVITRKTLEDLEEGRATVDQIEETEDVKRYLKGTSCIAGILVPVQGEPGRQEKMSIYQAMWKGLLRPGTALVLLEAQAATGFIIDPVHNRRLSVEEAVAAGVVGGEIQEKLLAAERAVTGYTDPYTGEQISLFQAMQRDLIVKDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYKRGYFDEEMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVYHVSEDLRRALREARVSPGTVDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLSVQDVSTTLTSLLARTKEGSPRADPQGTLGKATMEVKRGHLRGHEVPVWDVLTSNYVSRDTRKELLAQFSSGALTLPMLKRRLTTIIEETEETQESQAGHSVTSLKQQESAAGSSGAYADKGEAGDSTDSARQQQEQTLRAATMQVRRGQFRDQPVSVWKVLFSSYLSETRREELLSQHLAGRLGVNELISILVQVIEETEERLSRVSLPGLRRQVTVSELGNTGILDPDTMRELAQGTRTIDEVTEMDSVKRYLKGTSCIAGILVPVQGEPGRQEKMSIYQAMWKGLLRPGTALVLLEAQAATGFIIDPVHNRRLSVEEAVAAGVVGGEIQEKLLAAERAVTGYTDPYTGEQISLFQAMQRDLIVKDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYKRGYFDEEMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVYHVSEDLRRALREARVSPGTVDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLSVQDVSTTLTSLLARTKEGSPRADPQGTLGKATMEVKRGHLRGHEVPVWDVLTSNYVSRDTRKELLAQFSSGALTLPMLKRRLTTIIEETEETQESQAGHSVTSLKQQESAAGSSGAYADKGEAGDSTDSARQQQEQTLRAATMQVRRGQFRDQPVSVWKVLFSSYLSETRREELLSQHLAGRLGVNELISILVQVIEETEERLSRVSLPGLRRQVTVSELGNTGILDPDTMRELAQGTRTIDEVTEMDSVKRYLKGTSCIAGILVPVQGEPGRQEKMSIYQAMWKGLLRPGTALVLLEAQAATGFIIDPVHNRRLSVEEAVAAGVVGGEIQEKLLAAERAVTGYTDPYTGEQISLFQAMQRDLIVKDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYKRGYFDEEMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVYHVSEDLRRALREARVSPGTVDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLSVQDVSTTLTSLLARTKEGSPRADPQGTLGKATMEVKRGHLRGHEVPVWDVLTSNYVSRDTRKELLAQFSSGALTLPMLKRRLTTIIEETEETQESQAGHSVTSLKQQESAAGSSGAYADKGEAGDSTDSARQQQEQTLRAATMQVRRGQFRDQPVSVWKVLFSSYLSETRREELLSQHLAGRLGVNELISILVQVIEETEERLSRVSLPGLRRQVTVSELGNTGILDPDTMRELAQGTRTIDEVTEMDSVKRYLKGTSCIAGILVPVQGEPGRQEKMSIYQAMWKGLLRPGTALVLLEAQAATGFIIDPVHNRRLSVEEAVAAGVVGGEIQEKLLAAERAVTGYTDPYTGEQISLFQAMQRDLIVKDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYKRGYFDEEMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVYHVSEDLRRALREARVSPGTVDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLSVQDVSTTLTSLLARTKEGSPRADPQGTLGKATMEVKRGHLRGHEVPVWDVLTSNYVSRDTRKELLAQFSSGALTLPMLKRRLTTIIEETEETQESQAGHSVTSLKQQESAAGSSGAYADKGEAGDSTDSARQQQEQTLRAATMQVRRGQFRDQPVSVWKVLFSSYLSETRREELLSQHLAGRLGVNELISILVQVIEETEERLSRVSFPGLRRQVTASELSITGILDPDTMRELAQGTRTIDEVTEMDSVKRYLKGTSCIAGILVPVQGEPGRQEKMSIYQAMWKGLLRPGTALVLLEAQAATGFIIDPVHNRRLSVEEAVAEGVVGGEIREKLLSAERAVTGYTDPYTGEQISLFQAMQRDLIVKNHGIRLLEAQIATGGVIDPVHSHRVPVDVAYKRGYFDEEMNSILADPGDDTKGFFDPNTHENLTYLQLLQRATVEPETGLLFLSLLKG", "length": 4488 }, "evidence": [ { "id": "A0A3Q1LMV9", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3ISA6-1", "protein_name": "Epiplakin", "gene_name": "eppk1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPALNNFQGPVAGVFLENSNETITIYQAYKKRLLNPGSCLALLEAQAATGGIIDPVKNRTCSVEDAVKEGIVGCELKEKLQLAERAIVGYTDPYTNQKISLFQAMQKDVIPKEYGIRLLEAQISAKGIYDPIEKCYLTEEQAYRRGHYDENLFRGQKDALKVFYDPNSQENLTYPTLIKKCTVAPETGLLLFPIYITFKGLRRGVTSAELLASKIIDQQTFENLHKGKTTTQDVMLMETVKEYLEGKKSIGGVALLSTNKKMSIYQAMRQGIIMPGTGLILLEAQAATGFMIDPVENKTYSVHEAIKQKIVGPEYHAKLLAAERAVTGYKDPYTGETISLFQALKKELIVKEHGIRLLEAQIATGGIIDPINSHRVPVDVAYKRGFFNEEMNAILEDTGDDTKGFFDPNTKENLTYLQLLDHCVIDPATGLTLLPIQDPSGNRNHTFIDYDIKKIFKGVKVKVTCGKYMGMTVSLWELLMSEYFTEQQRQDFIQQYKSRTLTIEILITKVLEIIEYSVKTAKVVFEGIREKVSATQLVEADIITENDLKDLREGKKTVKDVTEDESVQTYLQGKPGIAGVLLPDSQVMSIYQARQKGILRPGTSLVLLEAQAATGFIIDPIANRKFSVDDAVKARVVGVDVHAKLCSAEKAVTGYQDPYTGKKISLFQAMQKDLIVKDHGIRLLEAQIATGGIIDPVNSHRIPVHIAYKRGYFDTEMNQILNDPTDDTKGFFDPNTHENLTYMQLMSRCVTDQSTGLCLLKIKGNDKRVKIGDSIKETFQTTYVSVRYGRFSNKKVTLWDLLNSEYLFEEKRQELLKSYKSKIITTEEIIAIILKIIESKEVQRNADLSVEGLRGKVSILELQNLGIIDETTYKNVLEGKLTIKDLTEMGTVMNFLRGTSCIAGVLLQKSNRKMSIYQAKKENHLTPGTALCLLEAQAATGFIIDPIQAKKLTVEEALKQNVIVPELYEKLLAAEKAVTGYKDPYTGKKISLFEAIKKDLIVKQHGIRLLEAQIATGGIIDPITCLHLPLDVAFRKGYFDADLNQILSDKSDDTKGFFYPTTQENLTYMDMMARCIKDADTGLLFLPVTEKEKTQEKSQKFLSDFEIKEDFEKHKVVIPVGRFSGKSMSLWEILHSVYFTDEQRQQYFEKYRLAKINIQDVVTIVTTTIETLEQKEANSQTTMGLRKPVSVKQLHESGIIDTTTYKQLQNGKETLENMLKLESVQKYLKGTRSIAGVKLHPSGKVLSVYKAKNDGLLTADVALSLLEAQAATGYVIDPIKNTHHSVLEAVKAQLIGPEILEHLLLAERAVTGFTDPYTNEQICLFEAMKKGLIPQKQGQNLLHAQLATGGIVDPIGSHRVPVQIAIKQGFLSKETNDLLANIGKSENGFSDPQTKEPLNYSQLMSKCERDSTTSLLLLPVTENNAESSAYNEEQILNVFKEKSVITNAGKFADKRVSLWDALNSEYISAEKRKELLDQYKQNKLSIEEITQIVTAIIIEVTTKRHSFKGLRRQVSASELFEAKIISKEMIGKLINNEVDDEDINNMESIQKYLGATNCIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVAEGIVGMEWKSKLLSAERAVTGYTDPYTGKTISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPIHSHRVPVEVAYQRGYFDEEMNKILADPDDDTKGFFDPNTQENLTYLQLVDRCVRDPNTCLSLLVIVKKGEYYFFIDDHTKNILKSTTTKKAGGKFQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVLQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRGYFDEEMNKILSDPDDDTKGFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRGYFDEEMNKILSDPDDDTKCFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRGYFDEEMNKILSDPDDDTKCFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRGYFDEEMNKILSDPDDDTKCFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPIYSHRVPVEVAYQRGYFDEEMNKILADPDDDTKGFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKFQGQLVTLWDLLYSSYISEEKKRELVQQFKSGTITIKQFLEIVLTLVSQKSVTSTHTITSTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRSYFDEEMNKILSDPDDDTKGFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRGYFDEEMNKILSDPDDDTKCFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPIYSHRVPVEVAYQRGYFDEEMNKILADPDDDTKGFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKFQGQLVTLWDLLYSSYISEEKKRELVQQFKSGTITIKQFLEIVLTLVSQKSVTSTHTITSTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRSYFDEEMNKILADPDDDTKGFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITSTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRGYFDEEMNKILSDPDDDTKGFFDPNTQENLTYLQLVERCVRDPNTGLSLLVIVKKGEYYFFIDEHTKNILKSTTTKKAGGKYQGQLVTLWDLLYSSYISEEKRRELVQQFKSGTITIEQFLEIVLTLVSQKSVTSTHTITTTTTTETTQNTNFQGIRKDVSADELLQSKVIDEKIYKDLTSGKVTVDHVSKMDSVRKYLKGTNSIAGVFVQSTKQTMSIFEAKNKGLLTPGTSLVLLEAQAATGFVIDPVKNKKLSVEQAVSEGIVGVEWKNKLLSAERAVTGYTDPNTGKIISLFQALKKDLIVKEHGIRLLEAQIATGGIIDPVYSHRVPVEVAYQRGYFDEEMNKILSDPDDDTKGFFDPNTQENLTYLLLVERCVKDPKTGLSLLVLKK", "length": 5476 }, "evidence": [ { "id": "A0A3Q1LMV9", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P58107-1", "protein_name": "Epiplakin", "gene_name": "EPPK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGHTLPPLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIAGVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQGLVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGLVDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLDPNTLERLTYHQLLERCVRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAEVRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITGQRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLALRLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQAGSFSDGTHGGLRYEQLLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPVSLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAKLSATLEQAAATARVTFSGLRDTVTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASVQRYLQGTGCIAGLLLPGSQERLSIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLLSAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPLSSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQREVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPEALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGTIMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGLIPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSETFPTPDGQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLWDLLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVPAVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASIAQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQAERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAAACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPSDTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGRAAALRQVVSAVTTLVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTTTVKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAATGFIIDPVENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKMRVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQNQGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSGCIAGVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVGLVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGVIDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRPQEDTGWLLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVTEEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSAIITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRCQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGHQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLAHPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVMPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSGAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEAHRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ", "length": 5088 }, "evidence": [ { "id": "A0A3Q1LMV9", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0W0-1", "protein_name": "Epiplakin", "gene_name": "Eppk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGQAPPHDVVVANGTEKFIVPKIKKNQLGASTPSRPQAEAALPTTARSIAGVYVEASGQTQSIYAAIKQGLLPTGLGLTLLEAQAATGGLVDLAQGQLLPVSEALRRGLVGLELKEKLLAAERAVTGYPDPYGGEKLSLFQAIKKEVVDRTLGWRLLEAQLATGGLVDPTQGVQVAPELACQQGLLDKETWLSLVESEPSMGTPGFSDPNTLEQLPYSVLLGRCVQDPSSGLPLLPLKTTFHTLAGAASASMLLEAGVLNEEMVRDLQEGMLVVSDVGTRPEVRRYLEGTGGLAGVVLLPGGHKKSFFQATVEHLVSKGIALQLLEAQAATRTLVHPTTGQRLWVEEAVKAGLVGPELHEQLLVAEQAVTGYYDPFSSSRIPVFQAMKKGLVDQPLALRLLDAQLATGGLICPARRFRLPLEAALRFGCLDEETRQRLSQAMGFSDPTTHDRLGYEQLLALSVTDPETGLAFLPLPGMSHANEPQGPTFIDHCTRQALSKATTSISVGRYQGRPVSLWELLFSESVPVKKRAMLAQRHQEGALSVEELAAELKNIVEQAAATAKVTFAGLRDTVTPGELLKAEIINQDLFEQLERGQTSAQDVGSLDSVQRYLQGTGSIAGLLLPDSQERLSIYEARSKGLLRPGTALILLEAQAATGFIIDPKENKRYSVEEALRAGVIGPDVYAKLLSAEHAVTGYTDPYSGEQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDQILNSILLDPSDDTKGFFDPNTHENLTYLQLLERCVHDSETGLHLLPLSSTRPQLVDSSTRQAFQKLLLSVKYGRFRGQRVSAWELVNSEYFTEDRRRQLLQRYRQRKITLEQVTQLLEKEMRRWTDITLPALQGQVTAYQLLEAHIINQELLDQVLTGTISPDALLQVGDVHRYLRGSGTVGGVLLKPSNQRISLYQAMKQKLLPPSTALALLEAQAATGTITDPCSMETLSVDEAVCRGVVGAEVYGKLKRAEHSITGYRDPFSGKKVSLFRAMKKGLVPVEQATRLLEAQVSTGGVVDPTTHLHLPMPVAVQRGCIDREMEAALSRSPETFPTPDGRGHTSYAQLLEHCLQDKASGLHLLPLTEDAPNVPTDTQIQETLQASAGTEDGLSLWDLLTSCHFTEEQRRGYLEDVKVGKISVPQLQNTVRSWVHSAKLLARARITVPGPRGEVPATWLRDAGIITQETLEALAQGMQSPDEVAKQPTVKVCLWGTGCVAGVLLQPSGTKLSIAQAVRDGLLPTGLGQQLLEAQVASGFLVNPLTNQRLSVEGAVKAGLVGMEQSEHLRQVEKAVTGYSDPFSGGSLSLWQAMEKGLVTQSEAFPLLQVQLATGGVVDPVHGVHLPQEVAYKLGLLDEQTSRVLTATGKENKLFFDPNSREKVTYQQLRELCVLDADTGLWLLPLPQGTVLEVDDHTAVALRAMKVPINMGRFQGHSVSLWDLLHSEYVGAEKRRELVALCCSGRAAALRQVIGMLTTLVEAAEKQPSQATFKGLRKQVSAGDLFRSQLITKQTLDELNQGKRTVQEVTEMDSVRRSLEGGNFIAGVLIQDTKEKMSIPEALRRHILRPGTALVLLEAQAATGFIIDPVENRKLTVEQAFQAGMFGKETYMKLLSAERAVTGYTDPYTGEQISLFQAMQRDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFNEEMNRILSDPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLYMLEIVKKGETYTYIDEATRQALTSRTVKMYVGKFAGQTVSVWDLLSSQYFTEGRRRKLLREYRAQNIGLENLLEVITSTVEETEKQSQIFKVPGIHGDVTAAELFNSGILNKKTLDALRSGDRGFQDLRWLEDVRVYLEGSNYIAGVIAPLTQKVMSFYEASREELIPAGFAAQMLEAQAATGYLMDPCTNQRLCVDEAIAAGLVGEDLRERLVNAEMAAKGYKDPATGETIPLYQAMERKLVGREEALRLLEVQVATGGVIDPRHHHRVPLDTACQRGCMCDDSLVLIADQKHMRKRFVDPNTQEKVTYQELQDRCQREEKSGWALFPVVKDKKDIEYVDEATKRALEAEQVEVTVGRYRGQRRSVWELLNSEYVSEEKKMELVRLYKEDTTRALQKVVELILQMIADKERRSRQLWFRGLRTQVTAEELLRSEVITKQTLEDLEEGRTTVDQIERKEDVKRYLKGTSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRCYQAGGLTVHDVTTTLTSLLARAKDGSPRGDPQGALGKATMEVKRGHLRGHEVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPRXDPQGALGKATMEVKRGHLRGHXVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVRDHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDEDMNSILADPGDDTKGFFDPNTHENLTYLQLLRRCVRDPETGFYMLQLAGKGSSVHHLSEELRRALREARVTPGTGDFQGQSISVWELLFYREVPESLRQDLLRRYQAGGLTVHDVTTTLTSLLARAKDGSPREDPQGALGKATMEVKRGHLRGHVVPVWDILTSNYVSRDTRKELLAQFSSGSLTLPMLKRRLTTIIEEAEETQESKPKPRDASLKQQDTGARGSGTSPDEGDAQDSSESARQQQEQTLRATTMQVHRGQFRDQQVSVWKVLFSSYLSETRREELLAQHLAGKLGVMELVSLLTQIIEETEERLSKVSFPGLRRQVSASELCTSGILDRDTMRELAQGTKTIHEVTEMDSVKRYLGGSSCIAGVLVPVQGEPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFIIDPVNNRRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGDQISLFQAMQRDLIVKNHGIRLLEAQIATGGVIDPVHSHRVPVDVAYQRGYFDQEMNSILADPGDDTKGFFDPNTHENLTYLQLLQRATIDPETGLLFLSLSKG", "length": 6548 }, "evidence": [ { "id": "A0A3Q1LMV9", "url": "https://omabrowser.org/oma/group/A0A3Q1LMV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "keratin filament binding", "id": "GO:1990254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990254", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intermediate filament bundle assembly", "id": "GO:0045110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045110", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ], "pmid": "" }, { "name": "negative regulation of wound healing", "id": "GO:0061045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061045", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV9" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": 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"XP_005218574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218574" } ] }, { "name": "GPR114", "type": "synonym", "evidence": [ { "id": "XP_005218574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218574" } ] } ], "protein_names": [ { "name": "Adhesion G-protein coupled receptor G5", "type": "recommended", "evidence": [ { "id": "A0A3Q1LN02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 114", "type": "synonym", "evidence": [ { "id": "A0A3Q1LN02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor PGR27", "type": "synonym", "evidence": [ { "id": "A0A3Q1LN02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02/entry#names_and_taxonomy" } ] }, { "name": "adhesion G-protein coupled receptor G5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005218574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218574" } ] } ], "function": [ { "annotation": "Orphan adhesion G-protein coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN02", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02#function" }, { "database": "UniProtKB", "id": "ARBA00093386", "url": "https://www.uniprot.org/uniprotkb/ARBA00093386#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN02", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADGRG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02", "locus": { "chromosome": "18", "start_pos": 25553434, "end_pos": 25526943, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005170", "url": "https://www.ensembl.org/id/ENSBTAG00000005170" } ] } } ], "crossref": [ { "id": "A0A3Q1LN02", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LN02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005170", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005170", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509974", "url": "https://www.ncbi.nlm.nih.gov/gene/509974", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RIHVNLH", "url": "https://omabrowser.org/oma/group/RIHVNLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LN02", "url": "https://www.orthodb.org/?gene=A0A3Q1LN02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QUL0", "url": "https://www.orthodb.org/?gene=F6QUL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011:SF326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011:SF326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005218574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN02", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN02-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QUL0", "url": "https://www.uniprot.org/uniprotkb/F6QUL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QUL0-1", "url": "https://www.uniprot.org/uniprotkb/F6QUL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNCCWAPFLYLCLLVSQSRTAEASQETLHWMEKMEVAAKSRISTSSAELIHGLELRLLNASFGGHNLTLQTQIIQALAFKLNCNFSGLSLSSAALEKVPQARPQHAMQFPAELTRNACRTRSRDLRLICIYFSSTRFFQKDINSSLLNNYVLGAQLSHGYVSNLSEPVNISFWHNQSLEGYTVTCVFWKERASKHHWGAWSPEGCHTEQPTPSQVLCRCNHLTYFAVLMQLSQAPVPAELLAPLTYISLVGCSISIVASLLTVLLHLQARYSPALMQGLLPSAAQNASFFSTWPRENQVGFPGRQKARGAGVEADKPHCVWLLLGPCPSLLTRVPVIMCLRAQGAALPGDIQVAEGHAPTRRKQSDSVTRIHMNLHASVLLLNITFLLSPVLATPPAPGAACVVLAATLHYALLSCLTWMAIEGFNLYLLLGRVYNVYIRRYVLKLCAVGWGVPAFLVLFLLAVKSSVYGPYKIQLSDSHGNSTGFKITSICWVQSSWVHSVLVMGYGGLTSLFNLVVLAWALRVLNKLRAQEKAPGTRACRDTVTVLGLTVLLGTTWALAFFSFSVFLLPQLFLFTIFNSLYGFFLFLWFCSQRCRSEAEAEAEMEVFTSQMVQ", "length": 615, "header": "tr|A0A3Q1LN02-1|A0A3Q1LN02_BOVIN Isoform 1 of Adhesion G-protein coupled receptor G5 OS=Bos taurus OX=9913 GN=ADGRG5 PE=3 SV=1 CANONICAL=A0A3Q1LN02-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LN02-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN02/entry", "sequence": { "sequence": "MNCCWAPFLYLCLLVSQSRTAEASQETLHWMEKMEVAAKSRISTSSAELIHGLELRLLNASFGGHNLTLQTQIIQALAFKLNCNFSGLSLSSAALEKVPQARPQHAMQFPAELTRNACRTRSRDLRLICIYFSSTRFFQKDINSSLLNNYVLGAQLSHGYVSNLSEPVNISFWHNQSLEGYTVTCVFWKERASKHHWGAWSPEGCHTEQPTPSQVLCRCNHLTYFAVLMQLSQAPVPAELLAPLTYISLVGCSISIVASLLTVLLHLQARYSPALMQGLLPSAAQNASFFSTWPRENQVGFPGRQKARGAGVEADKPHCVWLLLGPCPSLLTRVPVIMCLRAQGAALPGDIQVAEGHAPTRRKQSDSVTRIHMNLHASVLLLNITFLLSPVLATPPAPGAACVVLAATLHYALLSCLTWMAIEGFNLYLLLGRVYNVYIRRYVLKLCAVGWGVPAFLVLFLLAVKSSVYGPYKIQLSDSHGNSTGFKITSICWVQSSWVHSVLVMGYGGLTSLFNLVVLAWALRVLNKLRAQEKAPGTRACRDTVTVLGLTVLLGTTWALAFFSFSVFLLPQLFLFTIFNSLYGFFLFLWFCSQRCRSEAEAEAEMEVFTSQMVQ", "length": 615, "header": "tr|A0A3Q1LN02-1|A0A3Q1LN02_BOVIN Isoform 1 of Adhesion G-protein coupled receptor G5 OS=Bos taurus OX=9913 GN=ADGRG5 PE=3 SV=1 CANONICAL=A0A3Q1LN02-1" }, "locus": { "chromosome": "18", "start_pos": 25552059, "end_pos": 25541109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081065.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081065.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058308.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058308.1" } ] } }, { "isoform_ac": "F6QUL0-1", "url": "https://www.uniprot.org/uniprotkb/F6QUL0/entry", "sequence": { "sequence": "MNCCWAPFLYLCLLVSQSRTAEASQETLHWMEKMEVAAKSRISTSSAELIHGLELRLLNASFGGHNLTLQTQIIQALAFKLNCNFSGLSLSSAALEKVPQARPQHAMQFPAELTRNACRTRSRDLRLICIYFSSTRFFQKDINSSLLNNYVLGAQLSHGYVSNLSEPVNISFWHNQSLEGYTVTCVFWKERASKHHWGAWSPEGCHTEQPTPSQVLCRCNHLTYFAVLMQLSQAPVPAELLAPLTYISLVGCSISIVASLLTVLLHLQARKQSDSVTRIHMNLHASVLLLNITFLLSPVLATPPAPGAACVVLAATLHYALLSCLTWMAIEGFNLYLLLGRVYNVYIRRYVLKLCAVGWGVPAFLVLFLLAVKSSVYGPYKIQLSDSHGNSTGFKITSMFLPLPVVLLSEVPLRGRGRGRDGGVHLPDGAVGWTTWTFWPGAPSLSGCLQKRRWQPSYWRTEATVASWGPFLPPWLPQARGAGCCSTSSGILLRGKSTPPGGSQLAPGASAQLARPVTRALVAESKGHVSAPGSESHCLTLDLSFLTDPQFPHL", "length": 554, "header": "tr|F6QUL0-1|A0A3Q1LN02_BOVIN Computationally mapped isoform of Adhesion G-protein coupled receptor G5 OS=Bos taurus OX=9913 GN=ADGRG5 PE=3 SV=3 CANONICAL=A0A3Q1LN02-1" }, "locus": { "chromosome": "18", "start_pos": 25552430, "end_pos": 25541109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046723.4", "url": "https://www.ensembl.org/id/ENSBTAT00000046723.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043989.4", "url": "https://www.ensembl.org/id/ENSBTAP00000043989.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ANP6-1", "protein_name": "Adhesion G-protein coupled receptor G5", "gene_name": "ADGRG5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKMEVAAKKRSLISFADFIHGLEWRLLNVSFGGHNLTLKTHTIQTLAFKLGCNFTGLSLSSDTLERVPQAQARHAMQFPAELTRDACRTHTRELRLICIYFFTSHFFKKDINSSLLNNYVLGAQLGHGPVNNLSDRVNISFWHNQSLESYTVTCVFWKEGASKDYWGAWSPEGCLTEQPSPSQVLCRCNHLTYFAVLMQLSPAPVPATLLAPLLYISLVGCSISIVASLLTVLLQFYARKQSDSTTRIHMNLNSSVLLLNVAFLLSPVWAVPGSACTVLGATLHYMLLSCLTWMAIEGFNLYLLLGRVYNIYFRRYVLKLCAVGWGVPAFLVLLLLATNSSVYGPHRIPLSDSQRNGTDFQNMSICWVRNPDVHSVLVMGYGGLMSLFNLVVLVWALRVLRRLRVQEKPPGPRACRDTVTVLGLTVLLGTTWALAFFSFGVFLLPQLFLFTIFNSFYGFFLFLWFCSQRCRAEAEAEAEMEAFSSSQAMQ", "length": 491 }, "evidence": [ { "id": "A0A3Q1LN02", "url": "https://omabrowser.org/oma/group/A0A3Q1LN02/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1A5B2-1", "protein_name": "Adhesion G protein-coupled receptor G5", "gene_name": "ADGRG5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLTLLLAAFVLCLAEAVLPSQGTEYIQSCMHNLTEGLKRGSSRHNWARLTELEQLLAHSTPGKEGYSFKTNMLEAFVFSITAGSFRGLNLSSSMPVRSKGQVSAQLRDSISFPVELMEGMKAQEKQKLICICIRSAGMFLDEHNSSVLNNHILGAFLHNRRVGRLRRPVEIHFRHDKELDSSNATCVFWQPAGTGSAGNWSREGCETQHQKGIVRCLCNHLTYFAVLLIQAHDLSESELQSLTYISTVGCSISAAAALCTLLLCCVFRCRPRDDTTRIHMNLLAALLLLNVSFLLSEPLAAGTTGGCQAAAALLHGSLLCALGWMGAEGFHLYLLLIKVYNIYVRHYLLKLCLCTWGLPTLAVVAVLIFKREIYGHHIISTADGYKNVTMCWLTSPSAHYVTLCYAGLILLFNVLVLVAVVAVLRRTRQQQQQRARKDWMTVLGLTCLLGTTWGTAFCAFGVLLVPQLYLFTVLNSLQGQQPGGILGGGFPHPPGTALRVPMALTVPPPQVCSSAFGTSARTAASAAPTAVPPDSGAAGLASVFSVN", "length": 547 }, "evidence": [ { "id": "A0A3Q1LN02", "url": "https://omabrowser.org/oma/group/A0A3Q1LN02/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FP15-1", "protein_name": "Adhesion G-protein coupled receptor G5", "gene_name": "Adgrg5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTQRSLFFCLCILVAQSISQETLLPLLYLMKRLERPMGRALTSKVSPRNIHQLEQMLLNTSFFGHNLTLQTNSIQSLVFKLDCDFSGLSLSSATMANVSQAWAPHAMQFPAELTKDSCVTSRPAELRLICIYFFTAHLFQDDSNSSLLNNYVLGAQLDHRPVNNLQKPINISFWHNQSLEGYTVTCVFWKEGASKHSWGAWSPEGCYTEQPSPSQVLCHCNHLTYFAVLMQLSGDPVPAELQEPLEYISLVGCSISIVASLLTMLLYAHSRKQSDSITRIHMNLHGSVLLLNVTFLLSPQMALPTVPKSVCIALAATLHYALLSCLTWMAIEGYNLYLLLGHVYNVYIHRYLLKLCMLGWGFPALLVLLLLVIKSSVYGPYVISFSNSQDNGTGFQNVSMCWVCSPVVHSVLVMGYGGLMSLFNLVVLTWALWILCRLRIREKALSPWAYRDTVMVLGLTVLLGTTWVLAFFSFSVFRLPQLFLFTIFNSLYGFFLFLWFCLHRCHSDAEAKAEMEAVSSSQMTH", "length": 526 }, "evidence": [ { "id": "A0A3Q1LN02", "url": "https://omabrowser.org/oma/group/A0A3Q1LN02/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1M644-1", "protein_name": "Adhesion G-protein coupled receptor G5", "gene_name": "Adgrg5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQHQALFFCLCLLAAQVVLVETLPEILNLMKRLERPIGRALSSRVRFIHHLEQMLLNASFHGHNLTLQTNSIQSLVFKLSCGFPGLSLSSATLTNVSQAWAPHAMQFPAELTKNACVTSRPAELRLICVYFFTAHLFQDDRNSSLLNNYVLGAQLDHRPVNNLQRPVNISFWHNRSLEGYTVTCVFWKEGAGKHSWGAWSPKGCYTEQPSPTQVLCHCNHLTYFAVLMQLSGDPVPTELQTPLEYISLVGCSISIVASLLTILLNAHSRKLSDSTTRIHLNLNGSVLLLNITFLLSSQMVPPTVPRSVCTVLAATLHYALLSSLTWMGVEGFNLYLLLGRVYNVYIRRYLLKLCVLGWGFPALLVLLLLMIKSSVYGPCVISFSKSQENGTGFQNVSMCWVRSPMVHSILVMGYGGLTSLFNLVVLAWALWILCRLRKREKALSPWACRDIVMVLGLTVLLGTTWSLAFFSFSVFLLPQVFLFTIFNSLYGFFLFLWFCSQKRYSDAEAKAVMEAVSFSQMTH", "length": 524 }, "evidence": [ { "id": "A0A3Q1LN02", "url": "https://omabrowser.org/oma/group/A0A3Q1LN02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V3Z3-1", "protein_name": "Adhesion G protein-coupled receptor G5", "gene_name": "Adgrg5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPHGALFFYLCLLAAQVVLVETLSDLLVLMKRLEQPVGRGLSSRARHIHSLEQKLLNASFGGHNLTLQTNSIQSLVFKLSCDFPGLSLSSTTLTNVSQVRAPHAMQFPAELTKGACVTSRPAELRLICIYFFTAHLFQDDRNSSLLNNYVLGAQLDHRPVNNLQKPVNISFWHNRSLEGYTVSCVFWKEGASKSSWGAWSPEGCYTEQPSATQVLCHCNHLTYFAVLMQLSGDPVPAELQVPLEYISFVGCSISIVASLLTILLYAQSRKQSDSTTRIHMNLNGSVLLLNVTFLLSSQMTLPTMPRPVCKVLAAVLHYALLSSLTWMAIEGFNLYLFLGRVYNAYIRRYLLKLCMLGWGFPALLVLLLLMIKSSVYGPCVTSLSKSQENGTGFQNVSMCWIRSPMVHSILVMGYGGFTSLFNLVVLAWALWILCRLRAREKALSPWAYRDTAMVLGLTVLLGTTWTLAFFSFGVFLLPQLFLFTIFNSLYGFFLFLWFCSQKRYSDAEAKAEMEAVSSSQMTH", "length": 524 }, "evidence": [ { "id": "A0A3Q1LN02", "url": "https://omabrowser.org/oma/group/A0A3Q1LN02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZF4-1", "protein_name": "Adhesion G protein-coupled receptor G5", "gene_name": "ADGRG5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LN49-1", "uniprot_ac": "A0A3Q1LN49", "uniprot_id": "A0A3Q1LN49_BOVIN", "mass": { "chemical_mass": 76941.0, "monoisotopic_mass": 76941.0 }, "refseq": {}, "gene_names": [ { "name": "CDK17", "type": "recommended", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ], "protein_names": [ { "name": "cyclin-dependent kinase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LN49", "url": "https://www.orthodb.org/?gene=A0A3Q1LN49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MN42", "url": "https://www.orthodb.org/?gene=F1MN42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LN49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFS9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFS9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY13", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MN42", "url": "https://www.uniprot.org/uniprotkb/F1MN42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MN42-1", "url": "https://www.uniprot.org/uniprotkb/F1MN42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEASTRSRRVRKRRTRSGERLVGSAPSGGPREEEPVSGPAASAGRRRLPARLAPTPAPPRGLVGRLRDSAAREPCCPGGLATRERPAAPPGGSDSSARAGRRLRRRRPARRRRLGSASGWDPDLHPVAAGVGGAALPLRLPRLACSRDAAPALAGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF", "length": 688, "header": "tr|A0A3Q1LN49-1|A0A3Q1LN49_BOVIN Isoform 1 of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK17 PE=3 SV=2 CANONICAL=A0A3Q1LN49-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LN49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49/entry", "sequence": { "sequence": "MAEASTRSRRVRKRRTRSGERLVGSAPSGGPREEEPVSGPAASAGRRRLPARLAPTPAPPRGLVGRLRDSAAREPCCPGGLATRERPAAPPGGSDSSARAGRRLRRRRPARRRRLGSASGWDPDLHPVAAGVGGAALPLRLPRLACSRDAAPALAGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF", "length": 688, "header": "tr|A0A3Q1LN49-1|A0A3Q1LN49_BOVIN Isoform 1 of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK17 PE=3 SV=2 CANONICAL=A0A3Q1LN49-1" }, "locus": { "chromosome": "5", "start_pos": 60664853, "end_pos": 60555138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077282.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077282.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058198.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058198.2" } ] } }, { "isoform_ac": "A0AAA9SFS9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFS9/entry", "sequence": { "sequence": "MKGLPSTVVCVAVAFLRVFVPDGFCSPTRLESYRSAPSHHPLRATLTLLRFSPRSSLLTHSFSGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF", "length": 596, "header": "tr|A0AAA9SFS9-1|A0A3Q1LN49_BOVIN Computationally mapped isoform of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK17 PE=3 SV=1 CANONICAL=A0A3Q1LN49-1" }, "locus": { "chromosome": "5", "start_pos": 60663311, "end_pos": 60555138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108938.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108938.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085038.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085038.1" } ] } }, { "isoform_ac": "A0AAA9SY13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY13/entry", "sequence": { "sequence": "MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETDSENFAVKRIEAQIVNLEQMIRLKLTRFLKACNDK", "length": 546, "header": "tr|A0AAA9SY13-1|A0A3Q1LN49_BOVIN Computationally mapped isoform of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK17 PE=3 SV=1 CANONICAL=A0A3Q1LN49-1" }, "locus": { "chromosome": "5", "start_pos": 60595192, "end_pos": 60534571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123502.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123502.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088207.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088207.1" } ] } }, { "isoform_ac": "F1MN42-1", "url": "https://www.uniprot.org/uniprotkb/F1MN42/entry", "sequence": { "sequence": "MWCSPSNGILFSNKKQTAGTGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF", "length": 553, "header": "tr|F1MN42-1|A0A3Q1LN49_BOVIN Computationally mapped isoform of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK17 PE=3 SV=3 CANONICAL=A0A3Q1LN49-1" }, "locus": { "chromosome": "5", "start_pos": 60635954, "end_pos": 60555138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001977.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001977.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001977.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001977.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell cycle phase transition", "id": "GO:1901987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901987", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", 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"https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LN92-1", "uniprot_ac": "A0A3Q1LN92", "uniprot_id": "A0A3Q1LN92_BOVIN", "mass": { "chemical_mass": 77045.0, "monoisotopic_mass": 77045.0 }, "refseq": {}, "gene_names": [ { "name": "TGM3", "type": "recommended", "evidence": [ { "id": "A0A3Q1LN92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ] } ], "protein_names": [ { "name": "protein-glutamine gamma-glutamyltransferase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LN92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.13", "type": "synonym", "evidence": [ { "id": "A0A3Q1LN92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TGM3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92", "locus": { "chromosome": "13", "start_pos": 52793537, "end_pos": 52836111, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001785", "url": "https://www.ensembl.org/id/ENSBTAG00000001785" } ] } } ], "crossref": [ { "id": "A0A3Q1LN92", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LN92", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001785", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SMVGWNF", "url": "https://omabrowser.org/oma/group/SMVGWNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LN92", "url": "https://www.orthodb.org/?gene=A0A3Q1LN92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MIC8", "url": "https://www.orthodb.org/?gene=F1MIC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11590:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11590:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00868", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00868", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "54816", "url": "https://www.rhea-db.org/rhea/54816", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN92-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIC8", "url": "https://www.uniprot.org/uniprotkb/F1MIC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIC8-1", "url": "https://www.uniprot.org/uniprotkb/F1MIC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGLQSVDWQIASNRQAHHTERFYGKDLLVRRGQLFQVSLTLSQGLSSGGRVTFTASTGPYPSESANTKAVFPLSNGTSSSGWGAQLVSSRNNVLNISILSPANAPIGRYTLNMQISSQGSDSTLKLGTFILLFNPWLQGRHPNTHTPSHQLRDVHGKEMEGMIFMGSGLIRGSLWNRGRFEEGILNICLSVLDNSLNFRRDPATDVAHRNDPKYVGRVLSAMINGNDDSGVISGNWSGSYTGGRDPRNWNGSVEILKEWQRSGFRPVRYGQCWVFAGTLNTVLRCLGIPSRVITNFNSAHDTDQNLSVDVYYDPLGRPMDKGSDSVWNFHVWNEAWFVRSDLGPSYNGWQVLDATPQERSQGVFQCGPASVIAIREGNVDWDFDMPFIFAEVNADRITWIYESNGALKKNSADTHSVGKYISTKAVGSNSRMDVTEKYKYPEGSSQERQVFEKALRKLKPTMSFSATSASSLAREEREPSISGRFKVAGVLTVGKEVNLILMLKNLTSDTKTVTVNMTAWTIVYNGTLVHEVWKDSVTKSLNPEEEIEHPVKIAYAQYEKYLKADNMIRTTAVCQVTDEPEVVVERDIILDNPTLTLEVLDEARVQKPVNVQMLFSNPLDEPVKDCVLMVEGSGLLLGNLKIDVPALRPKERSRVRFEILPTRSGTKQLLANFSCNKFPAIKAMLSVDVAE", "length": 693, "header": "tr|A0A3Q1LN92-1|A0A3Q1LN92_BOVIN Isoform 1 of protein-glutamine gamma-glutamyltransferase OS=Bos taurus OX=9913 GN=TGM3 PE=3 SV=1 CANONICAL=A0A3Q1LN92-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LN92-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92/entry", "sequence": { "sequence": "MALGLQSVDWQIASNRQAHHTERFYGKDLLVRRGQLFQVSLTLSQGLSSGGRVTFTASTGPYPSESANTKAVFPLSNGTSSSGWGAQLVSSRNNVLNISILSPANAPIGRYTLNMQISSQGSDSTLKLGTFILLFNPWLQGRHPNTHTPSHQLRDVHGKEMEGMIFMGSGLIRGSLWNRGRFEEGILNICLSVLDNSLNFRRDPATDVAHRNDPKYVGRVLSAMINGNDDSGVISGNWSGSYTGGRDPRNWNGSVEILKEWQRSGFRPVRYGQCWVFAGTLNTVLRCLGIPSRVITNFNSAHDTDQNLSVDVYYDPLGRPMDKGSDSVWNFHVWNEAWFVRSDLGPSYNGWQVLDATPQERSQGVFQCGPASVIAIREGNVDWDFDMPFIFAEVNADRITWIYESNGALKKNSADTHSVGKYISTKAVGSNSRMDVTEKYKYPEGSSQERQVFEKALRKLKPTMSFSATSASSLAREEREPSISGRFKVAGVLTVGKEVNLILMLKNLTSDTKTVTVNMTAWTIVYNGTLVHEVWKDSVTKSLNPEEEIEHPVKIAYAQYEKYLKADNMIRTTAVCQVTDEPEVVVERDIILDNPTLTLEVLDEARVQKPVNVQMLFSNPLDEPVKDCVLMVEGSGLLLGNLKIDVPALRPKERSRVRFEILPTRSGTKQLLANFSCNKFPAIKAMLSVDVAE", "length": 693, "header": "tr|A0A3Q1LN92-1|A0A3Q1LN92_BOVIN Isoform 1 of protein-glutamine gamma-glutamyltransferase OS=Bos taurus OX=9913 GN=TGM3 PE=3 SV=1 CANONICAL=A0A3Q1LN92-1" }, "locus": { "chromosome": "13", "start_pos": 52824406, "end_pos": 52794039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079756.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079756.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058423.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058423.1" } ] } }, { "isoform_ac": "F1MIC8-1", "url": "https://www.uniprot.org/uniprotkb/F1MIC8/entry", "sequence": { "sequence": "MSGLQSVDWQIASNRQAHHTERFYGKDLLVRRGQLFQVSLTLSQGLSSGGRVTFTASTGPYPSESANTKAVFPLSNGTSSSGWGAQLVSSRNNVLNISILSPANAPIGRYTLNMQISSQGSDSTLKLGTFILLFNPWLQADSVFMSNHAEREEYVQEDAGIIFVGSTNRISMIGWNYGQFEEGILNICLSVLDNSLNFRRDPATDVAHRNDPKYVGRVLSAMINGNDDSGVISGNWSGSYTGGRDPRNWNGSVEILKEWQRSGFRPVRYGQCWVFAGTLNTVLRCLGIPSRVITNFNSAHDTDQNLSVDVYYDPLGRPMDKGSDSVWNFHVWNEAWFVRSDLGPSYNGWQVLDATPQERSQGVFQCGPASVIAIREGNVDWDFDMPFIFAEVNADRITWIYESNGALKKNSADTHSVGKYISTKAVGSNSRMDVTEKYKYPEGSSQERQVFEKALRKLKPTMSFSATSASSLAREEREPSISGRFKVAGVLTVGKEVNLILMLKNLTSDTKTVTVNMTAWTIVYNGTLVHEVWKDSVTKSLNPEEEIEHPVKIAYAQYEKYLKADNMIRTTAVCQVTDEPEVVVERDIILDNPTLTLEVLDEARVQKPVNVQMLFSNPLDEPVKDCVLMVEGSGLLLGNLKIDVPALRPKERSRVRFEILPTRSGTKQLLANFSCNKFPAIKAMLSVDVAE", "length": 691, "header": "tr|F1MIC8-1|A0A3Q1LN92_BOVIN Computationally mapped isoform of protein-glutamine gamma-glutamyltransferase OS=Bos taurus OX=9913 GN=TGM3 PE=3 SV=2 CANONICAL=A0A3Q1LN92-1" }, "locus": { "chromosome": "13", "start_pos": 52836054, "end_pos": 52794039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006432.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006432.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006432.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006432.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NXS5-1", "protein_name": "protein-glutamine gamma-glutamyltransferase", "gene_name": "TGM3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGQAAAQPSTDWHVKENGRDHHTSKFSSKELIVRRGQAFVITFNGVEQPEQTLTFIVETGPKPSKQAKTQATFGISSTVSKDSWSAVLQSTSSHSVSVSISSPPNAVIGRYKLSVQSTSTGSSSPETLGTFVLLFNPWSSGDNVFMPNKAECEEYVLEEFGIIFAGNNYHINSFGWNFGQFQADILNICLSMLDRSLNYRQDPATDVSHRHDPKYLGRVLSAMVNANDDQGVVLGNWSGNYDGGKSPSSWTGSGEILQSWKKSGFKPVRYGQCWVFAAVLTTVLRCLGIPTRPITNFSSAHDADGNLRVDEFYDASGNHLNEGADSVWNFHVWNESWFSRSDLGPSYSGWQILDATPQEESGGIYQCGPASRNAVKEGDVDLDYDCPFVFAEVNADCMYWSYDRATRKKTLLFNKSTVIGQLISTKAVGRDDRIDITSDYKYEEGSKKERDIFKKARKKLGLEDKFDPTAPTPKEIEQKPDISGKFKMAGPLEVGKDLNLILVLKNLQSEVKSVNVNMTAWSTVYTRRPVREIWKDSLSVSLSPEEEKHFPIKISYAEYQQQLTTDNAIEVTALCHVEGGIQVLVQRHIALDNPTIDIQVLGEAKVNEEMDVEVVFTNPIDIEVKDCVLQVEGSDLVRGILKIDVPPLKAKDISSTKFKLTPFETGSKHLLVNFSCDKFADIKAFKTVKVID", "length": 692 }, "evidence": [ { "id": "A0A3Q1LN92", "url": "https://omabrowser.org/oma/group/A0A3Q1LN92/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A5U3-1", "protein_name": "Protein-glutamine gamma-glutamyltransferase E", "gene_name": "Tgm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALEVQNINWQMPMNRRAHHTDKFSSQDFIVRRGQPWEVILLCNRSLESGDNLNFIVSTGPQPSESARTKAVFSISGRNTSGWSAALKASNGNNLFIAIASPVSAPIGLYTLNVEVSSKGRVSSVKLGTFTVLFNPWQQGDDVFMSNHAERQEYVEEDSGIIYVGSTNRIGMVGWNFGQFEEDILSISLSILDRSLNFRRDPATDVARRNDPKYVCRVLSAMINANDDSGVLSGNWSGNYSGGVDPRTWNGSVEILKNWKKSGFRPVQFGQCWVFAGTLNTVLRCLGVPSRVITNFNSAHDTDRNLSVDVYYDAMGNPLEKGSDSVWNFHVWNEGWFVRTDLGPSYNGWQVLDATPQERSQGVFQCGPASVNAIKDGEVDQNFDMIFIFAEVNADRITWIYNNRDGSQKQNSVDTYSIGKYISTKAVGSNSRMDVTIKYKHPEGSKEERQVQQKAMNKLKPNASFGATSSRGPQGEEKEPSISGKFKVTGVLAVGKEVSLALILKNTTSDRKTVTTNMTAWTIVYNGTLVHEVWKDSATISLDPEEEIQYPVKIAYSQYDRYLKADNMIRITAVCKVPDEAEVVVERDVILDNPTLTLEVLDQAQLRKPVVVQMLFSNPLDEPVKNCVLMVEGSGLLRGSLKIDVPALRPKEKSRVRFEIFPTRIGIKQLLADFSCNKFPAIKAMLVIEVSE", "length": 693 }, "evidence": [ { "id": "A0A3Q1LN92", "url": "https://omabrowser.org/oma/group/A0A3Q1LN92/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08188-1", "protein_name": "Protein-glutamine gamma-glutamyltransferase E", "gene_name": "TGM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVSTGPYPSESAMTKAVFPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHDTDRNLSVDVYYDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVVERDIILDNPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDVAE", "length": 693 }, "evidence": [ { "id": "A0A3Q1LN92", "url": "https://omabrowser.org/oma/group/A0A3Q1LN92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08189-1", "protein_name": "Protein-glutamine gamma-glutamyltransferase E", "gene_name": "Tgm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALQIQNVNWQVPMNRRAHHTDKFSSQDSIVRRGQPWEIILVCNRSLESGEDLNFIVSTGPQPSESARTKAVFSISGRSTGGWNAALKANSGNNLAIAIASPVSAPIGLYTLSVEISSRGRASSLKLGTFIMLFNPWLQADDVFMSNHAERQEYVEEDSGIIYVGSTNRIGMVGWNFGQFEEDILNISLSILDRSLNFRRDPVTDVARRNDPKYVCRVLSAMINGNDDNGVISGNWSGNYTGGVDPRTWNGSVEILKNWKKSGFRPVQFGQCWVFAGTLNTVLRCLGVPSRVITNFNSAHDTDRNLSVDVYYDAMGNPLEKGSDSVWNFHVWNEGWFVRTDLGPTYNGWQVLDATPQERSQGVFQCGPASVNAIKAGDVDRNFDMIFIFAEVNADRITWIYNNRNNTQKQNSVDTHSIGKYISTKAVGSNSRMDVTDKYKYPEGSSEERQVHQKALDKLKPNASFGATSSRNPEGEDKEPSISGKFKVTGILAVGKEVSLSLMLKNMTNDRKTVTMNMTAWTIVYNGTLVHEVWKDSATISLDPEEEIQYPVKIAYSQYERYLKADNMIRITAVCKVPDEAEVVVERDVILDNPALTLEVLEQAHVRKPVNVQMLFSNPLDQPVNNCVLLVEGSGLLRGSLKIDVPSLRPKEKSRIRFEIFPTRSGTKQLLADFSCNKFPAIKAMLPIDVSE", "length": 693 }, "evidence": [ { "id": "A0A3Q1LN92", "url": "https://omabrowser.org/oma/group/A0A3Q1LN92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" }, { "name": "extrinsic component of cytoplasmic side of plasma membrane", "id": "GO:0031234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031234", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" }, { "name": "protein-glutamine gamma-glutamyltransferase activity", "id": "GO:0003810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003810", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "keratinocyte differentiation", "id": "GO:0030216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030216", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" }, { "name": "peptide cross-linking", "id": "GO:0018149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018149", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LN92", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54816", "name": "", "equation": "L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MI90-1", "A6QP57-1", "P12260-1", "P51176-1", "F1MBB7-1", "A0A3Q1LN92-1", "F1N2I1-1", "F1MW44-1" ], "evidence": [ { "id": "54816", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54816" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LN92", 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"https://www.uniprot.org/uniprotkb/A0A3Q1MI90" } ] }, { "ec_number": "2.3.2.13", "activity": "", "evidence": [ { "id": "A0A3Q1MI90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI90" } ] }, { "ec_number": "3.5.1.44", "activity": "", "evidence": [ { "id": "A0A3Q1MI90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI90" } ] } ] }, { "uniprot_ac": "A6QP57", "gene_name": "TGM3", "activity": [ { "ec_number": "2.3.2.13", "activity": "L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4(+).", "evidence": [ { "id": "A6QP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QP57" } ] }, { "ec_number": "2.3.2.13", "activity": "", "evidence": [ { "id": "A6QP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QP57" } ] } ] }, { "uniprot_ac": "F1MBB7", "gene_name": "TGM1", "activity": [ { "ec_number": "2.3.2.13", "activity": "L-glutaminyl-[protein] + 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"length": 1132, "header": "tr|A0A3Q1LMB3-1|A0A3Q1LMB3_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RC3H2 PE=4 SV=1 CANONICAL=A0A3Q1LMB3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3/entry", "sequence": { "sequence": "MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSVKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAIRAARSLGERTVTELILQHQNPQQLSANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLRQQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVIGSTETTGKIVPSTNGISNAENSVSQLIPRSTDSTLRALETVKKVGKVGTNGQNAAGPSVESVTENKIGSPPKTPVSNVAATSAGPTSAGTELNSVPPKSSPFITRVPVYPQHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPRFSENVSGTKFEDDHLSHYSPWSCGTIGSCINAIDSEPRDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGPIISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATSSAHYIERDRFIVTDLSGHRKHSSTGDLLSIELQQAKSNSLLLQREANALAMQQKWNSLDEGRHLTLNLLSKEIELRNGESDYTEDAADTKPDRDIELELSALDTDEPDGQGEQIEEILDIQLGISSQNDQLLNGTAVENGHPVQQHQEEPLEQKRQSLGEDRVILEEQKTILPVTSCFSQPLPVSISNASGLPITTSVSVGNLILKTHVMSEDKNDFLKSVANGKMVNS", "length": 1132, "header": "tr|A0A3Q1LMB3-1|A0A3Q1LMB3_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RC3H2 PE=4 SV=1 CANONICAL=A0A3Q1LMB3-1" }, "locus": { "chromosome": "11", "start_pos": 94061472, "end_pos": 94013638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075508.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075508.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058016.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058016.1" } ] } }, { "isoform_ac": "A0A3Q1LYP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYP1/entry", "sequence": { "sequence": "MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSVKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLRQQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVIGSTETTGKIVPSTNGISNAENSVSQLIPRSTDSTLRALETVKKVGKVGTNGQNAAGPSVESVTENKIGSPPKTPVSNVAATSAGPTSAGTELNSVPPKSSPFITRVPVYPQHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPEQWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRTDFSENVSGTKFEDDHLSHYSPWSCGTIGSCINAIDSEPRDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGPIISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATSSAHYIERDRFIVTDLSGHRKHSSTGDLLSIELQQAKSNSLLLQREANALAMQQKWNSLDEGRHLTLNLLSKEIELRNGESDYTEDAADTKPDRDIELELSALDTDEPDGQGEQIEEILDIQLGISSQNDQLLNGTAVENGHPVQQHQEEPLEQKRQSLGEDRVILEEQKTILPVTSCFSQPLPVSISNASGLPITTSVSVGNLILKTHVMSEDKNDFLKSVANGKMVNS", "length": 1111, "header": "tr|A0A3Q1LYP1-1|A0A3Q1LYP1_BOVIN Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RC3H2 PE=4 SV=1 CANONICAL=A0A3Q1LMB3-1" }, "locus": { "chromosome": "11", "start_pos": 94061472, "end_pos": 94013638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079076.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079076.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060760.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060760.1" } ] } }, { "isoform_ac": "A0AAA9TTF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTF7/entry", "sequence": { "sequence": "MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSVKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAIRAARSLGERTVTELILQHQNPQQLSANLWAAVRARGCQFLGPGKIDHCLIGYQGRVPVSRNR", "length": 214, "header": "tr|A0AAA9TTF7-1|A0A3Q1LMB3_BOVIN Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RC3H2 PE=4 SV=1 CANONICAL=A0A3Q1LMB3-1" }, "locus": { "chromosome": "11", "start_pos": 94061472, "end_pos": 94055661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095622.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095622.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100635.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100635.1" } ] } }, { "isoform_ac": "E1BP22-1", "url": "https://www.uniprot.org/uniprotkb/E1BP22/entry", "sequence": { "sequence": "MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTDIDVLPVNFALLQLVGAQVPDHQSVKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVASLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAIRAARSLGERTVTELILQHQNPQQLSANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLRQQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVIGSTETTGKIVPSTNGISNAENSVSQLIPRSTDSTLRALETVKKVGKVGTNGQNAAGPSVESVTENKIGSPPKTPVSNVAATSAGPTSAGTELNSVPPKSSPFITRVPVYPQHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPEQWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRTDFSENVSGTKFEDDHLSHYSPWSCGTIGSCINAIDSEPRDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGPIISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATSSAHYIERDRFIVTDLSGHRKHSSTGDLLSIELQQAKSNSLLLQREANALAMQQKWNSLDEGRHLTLNLLSKEIELRNGESDYTEDAADTKPDRDIELELSALDTDEPDGQGEQIEEILDIQLGISSQNDQLLNGTAVENGHPVQQHQEEPLEQKRQSLGKSKKQFCR", "length": 1127, "header": "tr|E1BP22-1|E1BP22_BOVIN Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RC3H2 PE=4 SV=4 CANONICAL=A0A3Q1LMB3-1" }, "locus": { "chromosome": "11", "start_pos": 94061472, "end_pos": 94013805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032789.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032789.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032718.6", "url": "https://www.ensembl.org/id/ENSBTAP00000032718.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 566, "start_aa": "Thr", "end_pos": 566, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr566", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 624, "start_aa": "Thr", "end_pos": 624, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr624", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of T-helper 17 cell differentiation", "id": "GO:2000320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000320", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "regulation of miRNA metabolic process", "id": "GO:2000628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000628", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:0000288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000288", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1036, "end_pos": 1038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1091, "end_pos": 1093, "annotation": "n_glycosylation_sequon" }, { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 410, "end_pos": 438, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMB3" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 54, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 566, 624 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1036, "end_pos": 1038 }, { "start_pos": 1091, "end_pos": 1093 }, { "start_pos": 122, "end_pos": 124 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 668, "end_pos": 670 }, { "start_pos": 765, "end_pos": 767 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LFL0-1", "uniprot_ac": "A0A3Q1LFL0", "uniprot_id": "A0A3Q1LFL0_BOVIN", "mass": { "chemical_mass": 66222.0, "monoisotopic_mass": 66222.0 }, "refseq": { "ac": "NP_001179840", "name": "phosphatase and actin regulator 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179840" }, "gene_names": [ { "name": "PHACTR1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0" } ] }, { "name": "PHACTR1", "type": "synonym", "evidence": [ { "id": "NP_001179840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179840" } ] } ], "protein_names": [ { "name": "Phosphatase and actin regulator", "type": "recommended", "evidence": [ { "id": "A0A3Q1LFL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0/entry#names_and_taxonomy" } ] }, { "name": "phosphatase and actin regulator 1", "type": "synonym", "evidence": [ { "id": "NP_001179840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179840" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFL0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PHACTR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0", "locus": { "chromosome": "23", "start_pos": 43276073, "end_pos": 43796814, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012039", "url": "https://www.ensembl.org/id/ENSBTAG00000012039" } ] } } ], "crossref": [ { "id": "A0A3Q1LFL0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LFL0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012039", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012039", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "537594", "url": "https://www.ncbi.nlm.nih.gov/gene/537594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:537594", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LFL0", "url": "https://www.orthodb.org/?gene=A0A3Q1LFL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPU4", "url": "https://www.orthodb.org/?gene=A0A3Q1LPU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N0D8", "url": "https://www.orthodb.org/?gene=F1N0D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N373", "url": "https://www.orthodb.org/?gene=G3N373", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12751:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12751:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179840", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFL0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPU4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXL7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXL7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6I2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6I2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0D8", "url": "https://www.uniprot.org/uniprotkb/F1N0D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0D8-1", "url": "https://www.uniprot.org/uniprotkb/F1N0D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N373", "url": "https://www.uniprot.org/uniprotkb/G3N373", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N373-1", "url": "https://www.uniprot.org/uniprotkb/G3N373-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDYPKMDYFLDVESAPRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDDIDRRPIRRVRSKSDTPYLAEARISFNLGAAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELSISNEDDSLENGQSLSSSQLSLPALSEMEPVPMPRDPCSYEVLQPADIMDGTDPGAPVKLPCLPVKLSPPLPPKKVMICMPVGGPELSLASYAAQKSGPQGGAQHHHTVLPSQIQHQLQYGSLGQHLPSTTGSLPLHPSGCRMIEELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDSVTKAGPLGLPEIRQVPTVVIECDDNKENVPHEADYEDSSCLYTREEEEEEDEDEDDDTSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "length": 581, "header": "tr|A0A3Q1LFL0-1|A0A3Q1LFL0_BOVIN Isoform 1 of Phosphatase and actin regulator OS=Bos taurus OX=9913 GN=PHACTR1 PE=3 SV=2 CANONICAL=A0A3Q1LFL0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0/entry", "sequence": { "sequence": "MDYPKMDYFLDVESAPRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDDIDRRPIRRVRSKSDTPYLAEARISFNLGAAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELSISNEDDSLENGQSLSSSQLSLPALSEMEPVPMPRDPCSYEVLQPADIMDGTDPGAPVKLPCLPVKLSPPLPPKKVMICMPVGGPELSLASYAAQKSGPQGGAQHHHTVLPSQIQHQLQYGSLGQHLPSTTGSLPLHPSGCRMIEELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDSVTKAGPLGLPEIRQVPTVVIECDDNKENVPHEADYEDSSCLYTREEEEEEDEDEDDDTSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "length": 581, "header": "tr|A0A3Q1LFL0-1|A0A3Q1LFL0_BOVIN Isoform 1 of Phosphatase and actin regulator OS=Bos taurus OX=9913 GN=PHACTR1 PE=3 SV=2 CANONICAL=A0A3Q1LFL0-1" }, "locus": { "chromosome": "23", "start_pos": 43794630, "end_pos": 43277362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086474.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086474.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056982.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056982.2" } ] } }, { "isoform_ac": "A0A3Q1LPU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU4/entry", "sequence": { "sequence": "MAEPTRAAEPGRFALRSPRCREGAVPGANAQRPKRKAFYLLRMKPLKQPAPNNNNNVSFAIHCQLGKEIKHICSNCSRGEDARDAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELSISNEDDSLENGQSLSSSQLSLPALSEMEPVPMPRDPCSYEVLQPADIMDGTVSEESPSASESGALLSQDPSAKPVLFLPPKKPAASPGDHEDTPVKQLSLLKQPPALPPKPTARIGNHLPDPGAPVKLPCLPVKLSPPLPPKKVMICMPVGGPELSLASYAAQKSGPQGGAQHHHTVLPSQIQHQLQYGSLGQHLPSTTGSLPLHPSGCRMIEELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDSVTKAGPLGLPEIRQVPTVVIECDDNKENVPHEADYEDSSCLYTREEEEEEDEDEDDDTSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKQVDMQAVVPHTMAAHVLCGLLGRVKELMESVLAKARNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "length": 685, "header": "tr|A0A3Q1LPU4-1|A0A3Q1LPU4_BOVIN Computationally mapped isoform of Phosphatase and actin regulator OS=Bos taurus OX=9913 GN=PHACTR1 PE=3 SV=2 CANONICAL=A0A3Q1LFL0-1" }, "locus": { "chromosome": "23", "start_pos": 43519201, "end_pos": 43277362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081911.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081911.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059028.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059028.2" } ] } }, { "isoform_ac": "A0ABI0NXL7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL7/entry", "sequence": { "sequence": "MALERKISMRQSREELIKRGVLKEIYDKDGELSISNEDDSLENGQSLSSSQLSLPALSEMEPVPMPRDPCSYEVLQPADIMDGTVSEESPSASESGALLSQDPSAKPVLFLPPKKPAASPGDHEDTPVKQLSLLKQPPALPPKPTARIGNHLPDPGAPVKLPCLPVKLSPPLPPKKVMICMPVGGPELSLASYAAQKSGPQGGAQHHHTVLPSQIQHQLQYGSLGQHLPSTTGSLPLHPSGCRMIEELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDSVTKAGPLGLPEIRQVPTVVIECDDNKENVPHEADYEDSSCLYTREEEEEEDEDEDDDTSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "length": 513, "header": "tr|A0ABI0NXL7-1|A0ABI0NXL7_BOVIN Computationally mapped isoform of Phosphatase and actin regulator OS=Bos taurus OX=9913 GN=PHACTR1 PE=3 SV=1 CANONICAL=A0A3Q1LFL0-1" }, "locus": { "chromosome": "23", "start_pos": 43374729, "end_pos": 43277362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137411.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137411.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104497.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104497.1" } ] } }, { "isoform_ac": "A0ABI0P6I2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6I2/entry", "sequence": { "sequence": "MAEPTRAAEPGRFALRSPRCREGAVPGANAQRPKRKAFYLLRMKPLKQPAPNNNNNVSFAIHCQLGKEIKHICSNCSRGEDARDAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELSISNEDDSLENGQSLSSSQLSLPALSEMEPVPMPRDPCSYEVLQPADIMDGTVSEESPSASESGALLSQDPSAKPVLFLPPKKPAASPGDHEDTPVKQLSLLKQPPALPPKPTARIGNHLPDPGAPVKLPCLPVKLSPPLPPKKVMICMPVGGPELSLASYAAQKSGPQGGAQHHHTVLPSQIQHQLQYGSLGQHLPSTTGSLPLHPSGCRMIEELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDSVTKAGPLGLPEIRQVPTVVIECDDNKENVPHEADYEDSSCLYTREEEEEEDEDEDDDTSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "length": 651, "header": "tr|A0ABI0P6I2-1|A0ABI0P6I2_BOVIN Computationally mapped isoform of Phosphatase and actin regulator OS=Bos taurus OX=9913 GN=PHACTR1 PE=3 SV=1 CANONICAL=A0A3Q1LFL0-1" }, "locus": { "chromosome": "23", "start_pos": 43519201, "end_pos": 43277362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147755.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147755.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106605.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106605.1" } ] } }, { "isoform_ac": "F1N0D8-1", "url": "https://www.uniprot.org/uniprotkb/F1N0D8/entry", "sequence": { "sequence": "MRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELSISNEDDSLENGQSLSSSQLSLPALSEMEPVPMPRDPCSYEVLQPADIMDGTDPGAPVKLPCLPVKLSPPLPPKKVMICMPVGGPELSLASYAAQKSGPQGGAQHHHTVLPSQIQHQLQYGSLGQHLPSTTGSLPLHPSGCRMIEELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDSVTKAGPLGLPEIRQVPTVVIECDDNKENVPHEADYEDSSCLYTREEEEEEDEDEDDDTSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "length": 489, "header": "tr|F1N0D8-1|A0A3Q1LFL0_BOVIN Computationally mapped isoform of Phosphatase and actin regulator OS=Bos taurus OX=9913 GN=PHACTR1 PE=3 SV=4 CANONICAL=A0A3Q1LFL0-1" }, "locus": { "chromosome": "23", "start_pos": 43473458, "end_pos": 43277362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035406.6", "url": "https://www.ensembl.org/id/ENSBTAT00000035406.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035281.6", "url": 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"start_pos": 43767972, "end_pos": 43277362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064101.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064101.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056347.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056347.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:537594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537594", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LFL0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL0" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": 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"categories": [ "Protein" ] }, { "id": "A0A3Q1LNA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSY0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWQ5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N0B9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N0B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N0B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N0B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B7J7", "url": "https://www.uniprot.org/uniprotkb/E1B7J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B7J7-1", "url": "https://www.uniprot.org/uniprotkb/E1B7J7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 559, "header": "tr|A0A3Q1LNA9-1|A0A3Q1LNA9_BOVIN Isoform 1 of Serine/threonine-protein kinase PAK 3 OS=Bos taurus OX=9913 GN=PAK3 PE=3 SV=1 CANONICAL=A0A3Q1LNA9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJ28-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ28/entry", "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 544, "header": "tr|A0A3Q1LJ28-1|A0A3Q1LNA9_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase PAK 3 OS=Bos taurus OX=9913 GN=PAK3 PE=3 SV=1 CANONICAL=A0A3Q1LNA9-1" }, "locus": { "chromosome": "X", "start_pos": 59389655, "end_pos": 59294063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084673.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084673.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059278.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059278.2" } ] } }, { "isoform_ac": "A0A3Q1LNA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9/entry", "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 559, "header": "tr|A0A3Q1LNA9-1|A0A3Q1LNA9_BOVIN Isoform 1 of Serine/threonine-protein kinase PAK 3 OS=Bos taurus OX=9913 GN=PAK3 PE=3 SV=1 CANONICAL=A0A3Q1LNA9-1" }, "locus": { "chromosome": "X", "start_pos": 59389655, "end_pos": 59294063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075606.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075606.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058285.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058285.1" } ] } }, { "isoform_ac": "A0A3Q1LSY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSY0/entry", "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTNSPFQTSRPVTVASSQSEGKMPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 580, "header": "tr|A0A3Q1LSY0-1|A0A3Q1LNA9_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase PAK 3 OS=Bos taurus OX=9913 GN=PAK3 PE=3 SV=1 CANONICAL=A0A3Q1LNA9-1" }, "locus": { "chromosome": "X", "start_pos": 59389655, "end_pos": 59294063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085260.1", "url": "https://www.ensembl.org/id/ENSBTAT00000085260.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060136.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060136.1" } ] } }, { "isoform_ac": "A0A3Q1LWQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWQ5/entry", "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTNSPFQTSRPVTVASSQSEGKMGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 565, "header": "tr|A0A3Q1LWQ5-1|A0A3Q1LWQ5_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase PAK 3 OS=Bos taurus OX=9913 GN=PAK3 PE=3 SV=2 CANONICAL=A0A3Q1LNA9-1" }, "locus": { "chromosome": "X", "start_pos": 59389655, "end_pos": 59294063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073639.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073639.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065137.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065137.2" } ] } }, { "isoform_ac": "A0A3Q1N0B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N0B9/entry", "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQVLLAGGNSLHNYAIISMAFATLMLYWSKPLCL", "length": 547, "header": "tr|A0A3Q1N0B9-1|A0A3Q1LNA9_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase PAK 3 OS=Bos taurus OX=9913 GN=PAK3 PE=3 SV=2 CANONICAL=A0A3Q1LNA9-1" }, "locus": { "chromosome": "X", "start_pos": 59386474, "end_pos": 59294063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082336.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082336.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062101.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062101.2" } ] } }, { "isoform_ac": "E1B7J7-1", "url": "https://www.uniprot.org/uniprotkb/E1B7J7/entry", "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGGKNKSKISKTSEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 536, "header": "tr|E1B7J7-1|A0A3Q1LNA9_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase PAK 3 OS=Bos taurus OX=9913 GN=PAK3 PE=3 SV=3 CANONICAL=A0A3Q1LNA9-1" }, "locus": { "chromosome": "X", "start_pos": 59389655, "end_pos": 59294063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013449.8", "url": "https://www.ensembl.org/id/ENSBTAT00000013449.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013449.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013449.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:534526", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534526", "resource": "KEGG Pathway" }, { "id": "R-BTA-202433", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-202433", "resource": "Reactome", "description": "Generation of second messenger molecules" }, { "id": "R-BTA-389359", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389359", "resource": "Reactome", "description": "CD28 dependent Vav1 pathway" }, { "id": "R-BTA-3928664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3928664", "resource": "Reactome", "description": "Ephrin signaling" }, { "id": "R-BTA-399954", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-399954", "resource": "Reactome", "description": "Sema3A PAK dependent Axon repulsion" }, { "id": "R-BTA-5218920", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5218920", "resource": "Reactome", "description": "VEGFR2 mediated vascular permeability" }, { "id": "R-BTA-5627123", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5627123", "resource": "Reactome", "description": "RHO GTPases activate PAKs" }, { "id": "R-BTA-5687128", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5687128", "resource": "Reactome", "description": "MAPK6/MAPK4 signaling" }, { "id": "R-BTA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HZH7-1", "protein_name": "Serine/threonine-protein kinase PAK 3", "gene_name": "Pak3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLENEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHQSNTKTASEPPLAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 544 }, "evidence": [ { "id": "A0A3Q1LNA9", "url": "https://omabrowser.org/oma/group/A0A3Q1LNA9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O75914-1", "protein_name": "Serine/threonine-protein kinase PAK 3", "gene_name": "PAK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR", "length": 559 }, "evidence": [ { "id": "A0A3Q1LNA9", "url": "https://omabrowser.org/oma/group/A0A3Q1LNA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "dendritic spine morphogenesis", "id": "GO:0060997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060997", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-BTA-389788", "name": "Activation of PAKs by RAC1 and CDC42", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q08E52-1", "Q2KJ93-1", "A0A3Q1LNA9-1" ], "evidence": [ { "id": "R-BTA-389788", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389788" } ] }, { "id": "R-BTA-3928625", "name": "PAKs autophosphorylate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "F1ML02-1", "Q08E52-1", "A0AAA9THG2-1", "A0A3Q1LNA9-1", "A0JNB0-1", "E1BIM8-1", "F1MII5-1", "F1N3R6-1" ], "evidence": [ { "id": "R-BTA-3928625", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3928625" } ] }, { "id": "R-BTA-3928640", "name": "PAKs phosphorylate MLC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-BTA-390735" ], "output_participant_list": [ "R-BTA-390749" ], "enzyme_list": [ "A0A3Q1M0G8-1", "F1ML02-1", "Q08E52-1", "A0AAA9THG2-1", "A0A3Q1LNA9-1", "A0JNB0-1", "E1BIM8-1", "F1MII5-1", "F1N3R6-1" ], "evidence": [ { "id": "R-BTA-3928640", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3928640" } ] }, { "id": "R-BTA-3928641", "name": "PAK binds RAC and bPIX", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "F1ML02-1", "Q08E52-1", "A0AAA9THG2-1", "A0A3Q1LNA9-1", "A0JNB0-1", "E1BIM8-1", "F1MII5-1", "F1N3R6-1" ], "evidence": [ { "id": "R-BTA-3928641", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3928641" } ] }, { "id": "R-BTA-399930", "name": "Activation of PAK by Rac1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q08E52-1", "A0A3Q1LNA9-1", "A0JNB0-1" ], "evidence": [ { "id": "R-BTA-399930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-399930" } ] }, { "id": "R-BTA-399939", "name": "Autophosphorylation of PAK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q08E52-1", "A0A3Q1LNA9-1", "A0JNB0-1" ], "evidence": [ { "id": "R-BTA-399939", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-399939" } ] }, { "id": "R-BTA-399952", "name": "Phosphorylation of LIMK-1 by PAK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "E1BC64-1", "Q08E52-1", "A0A3Q1LNA9-1", "A0JNB0-1" ], "evidence": [ { "id": "R-BTA-399952", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-399952" } ] }, { "id": "R-BTA-430183", "name": "NCK binds PAK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q08E52-1", "A0A3Q1LNA9-1" ], "evidence": [ { "id": "R-BTA-430183", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-430183" } ] }, { "id": "R-BTA-5357477", "name": "PAK1-3 phosphorylates VE-cadherin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q08E52-1", "A0A3Q1LNA9-1" ], "evidence": [ { "id": "R-BTA-5357477", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357477" } ] }, { "id": "R-BTA-5627775", "name": "Autophosphorylation of PAK1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "Q08E52-1", "Q2KJ93-1", "A0A3Q1LNA9-1" ], "evidence": [ { "id": "R-BTA-5627775", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5627775" } ] }, { "id": "R-BTA-5687086", "name": "PAK1,2,3 phosphorylates MAPK6,4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "F1MVV5-1", "G5E577-1", "Q08E52-1", "A0A3Q1LNA9-1" ], "evidence": [ { "id": "R-BTA-5687086", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5687086" } ] }, { "id": "R-BTA-8981926", "name": "RAC1 and CDC42 activate PAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KJ93-1", "A0A3Q1LNA9-1" ], "evidence": [ { "id": "R-BTA-8981926", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8981926" } ] }, { "id": "R-BTA-9018766", "name": "RHOU binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M0G8-1", "A5D7J5-1", "A0AAA9RXB5-1", "Q08E52-1", "Q2KJ93-1", "E1BJ31-1", "A0A3Q1LNA9-1", "A0A3Q1LVP1-1" ], "evidence": [ { "id": "R-BTA-9018766", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9018766" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-390735", "participant_name": "MYL12A [cytosol]", "crossref": [ { "id": "Q5E9E2", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000016024", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000021328", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000021328", "database": "ENSEMBL", "url": "" }, { "id": "XP_005224259.1", "database": "RefSeq", "url": "" }, { "id": "NP_001015640.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-390749", "participant_name": "phospho-p-S19-MYL12A [cytosol]", "crossref": [ { "id": "ENSBTAP00000021328", "database": "ENSEMBL", "url": "" }, { "id": "XP_005224259.1", "database": "RefSeq", "url": "" }, { "id": "Q5E9E2", "database": "UniProt", "url": "" }, { "id": "NP_001015640.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAT00000021328", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAG00000016024", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": 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"uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9RXB5", "gene_name": "USP9X", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0AAA9RXB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXB5" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0AAA9RXB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXB5" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5D7J5", "gene_name": "RHOU", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A5D7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7J5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A5D7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7J5" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJ93", "gene_name": "CDC42", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q2KJ93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ93" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": 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"A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-BTA-168162", "name": "Phosphorylation of human JNKs by activated MKK4/MKK7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LTC6-1", "A0AAA9S472-1", "A0A3Q1LJU7-1" ], "evidence": [ { "id": "R-BTA-168162", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-168162" } ] }, { "id": "R-BTA-2730896", "name": "Phosphorylation of MEK4 by MEKK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LTC6-1" ], "evidence": [ { "id": "R-BTA-2730896", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2730896" } ] }, { "id": "R-BTA-450337", "name": "Activated TAK1 phosphorylates MKK4/MKK7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-BTA-168107" ], "output_participant_list": [ "R-BTA-168170" ], "enzyme_list": [ "Q3SZJ2-1", "Q3ZCC3-1", "A0A3Q1LTC6-1", "Q0P5K3-1", "Q2LGB3-1", "A2VDU3-1" ], "evidence": [ { "id": "R-BTA-450337", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450337" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-168107", "participant_name": "MAP2K4 [cytosol]", "crossref": [ { "id": "A0A3Q1N7I1", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000012103", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000066673", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000066489", "database": "ENSEMBL", "url": "" }, { "id": "31185", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-168170", "participant_name": "phospho-p-S257,T261-MAP2K4 [cytosol]", "crossref": [ { "id": "ENSBTAP00000066673", "database": "ENSEMBL", "url": "" }, { "id": "31185", "database": "VGNC", "url": "" }, { "id": "A0A3Q1N7I1", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000012103", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000066489", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LI98", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LRR9", "gene_name": "TYRO3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR9" } ] } ] }, { "uniprot_ac": "A0A3Q1LT44", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LUE0", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": 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"id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": 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"2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SA57", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] } ] }, { "uniprot_ac": "A0AAA9SBR4", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SN20", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SPC9", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVL9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TMY2", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TQL1", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B6X6", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9H4", "gene_name": "PKDCC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BER5", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F1N6H6", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] } ] }, { "uniprot_ac": "F1N6J0", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N780", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] } ] }, { "uniprot_ac": "F1N781", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QXU6", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "F6S1J8", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] } ] }, { "uniprot_ac": "G1K218", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G3X680", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q05688", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] } ] }, { "uniprot_ac": "Q06805", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] } ] }, { "uniprot_ac": "Q06807", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q3ZCC3", "gene_name": "TRAF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q3ZCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q3ZCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCC3" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q769I5", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q769I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q769I5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q769I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q769I5" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": 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Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005215625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215625", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N9I7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N9I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9I7-1", "database": "UniProtKB", "categories": [ 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"MARRWNTKESPRWRSALVLLFLAGVYACGETPEQIRAPSGIITSPGWPSEYPARINCSWFIRANPGEIITISFQDFDIQGSRRCSLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPAAWKCNNMDECGDSSDEEICAREANPPTSASFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTVCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDTAGASGGVTAPLPQKVPPTTAVEATVGASGSSSTQSTRGGHTETGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSSNQNQSPLRQLDNGVNGREEDDDVEMLIPVSEGASDFDVNDCSRPLLDLASDQGQGFRQPYSGTNPGVRPSSRDGPCERCGIVHTAQIPDSCLEATLKTETSDDEALLLC", "length": 840, "header": "tr|A0A3Q1LUU5-1|A0A3Q1LUU5_BOVIN Isoform 1 of Low-density lipoprotein receptor-related protein 12 OS=Bos taurus OX=9913 GN=LRP12 PE=3 SV=1 CANONICAL=A0A3Q1LUU5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5/entry", "sequence": { "sequence": "MARRWNTKESPRWRSALVLLFLAGVYACGETPEQIRAPSGIITSPGWPSEYPARINCSWFIRANPGEIITISFQDFDIQGSRRCSLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPAAWKCNNMDECGDSSDEEICAREANPPTSASFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTVCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDTAGASGGVTAPLPQKVPPTTAVEATVGASGSSSTQSTRGGHTETGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSSNQNQSPLRQLDNGVNGREEDDDVEMLIPVSEGASDFDVNDCSRPLLDLASDQGQGFRQPYSGTNPGVRPSSRDGPCERCGIVHTAQIPDSCLEATLKTETSDDEALLLC", "length": 840, "header": "tr|A0A3Q1LUU5-1|A0A3Q1LUU5_BOVIN Isoform 1 of Low-density lipoprotein receptor-related protein 12 OS=Bos taurus OX=9913 GN=LRP12 PE=3 SV=1 CANONICAL=A0A3Q1LUU5-1" }, "locus": { "chromosome": "14", "start_pos": 60124356, "end_pos": 60035685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071234.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071234.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059012.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059012.1" } ] } }, { "isoform_ac": "A0A3Q1N9I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9I7/entry", "sequence": { "sequence": "MNMVTEVLSSGIHNCLACSFRDMSHPLNTGNRALAEHSENVHISGVSTACGETPEQIRAPSGIITSPGWPSEYPARINCSWFIRANPGEIITISFQDFDIQGSRRCSLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPAAWKCNNMDECGDSSDEEICAREANPPTSASFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTVCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDTAGASGGVTAPLPQKVPPTTAVEATVGASGSSSTQSTRGGHTETGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSSNQNQSPLRQLDNGVNGREEDDDVEMLIPVSEGASDFDVNDCSRPLLDLASDQGQGFRQPYSGTNPGVRPSSRDGPCERCGIVHTAQIPDSCLEATLKTETSDDEALLLC", "length": 862, "header": "tr|A0A3Q1N9I7-1|A0A3Q1LUU5_BOVIN Computationally mapped isoform of Low-density lipoprotein receptor-related protein 12 OS=Bos taurus OX=9913 GN=LRP12 PE=3 SV=1 CANONICAL=A0A3Q1LUU5-1" }, "locus": { "chromosome": "14", "start_pos": 60124356, "end_pos": 60062833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071287.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071287.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067824.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067824.1" } ] } }, { "isoform_ac": "A0AAA9SHS3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHS3/entry", "sequence": { "sequence": "MPELNKWWFLKACGETPEQIRAPSGIITSPGWPSEYPARINCSWFIRANPGEIITISFQDFDIQGSRRCSLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPAAWKCNNMDECGDSSDEEICAREANPPTSASFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTVCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDTAGASGGVTAPLPQKVPPTTAVEATVGASGSSSTQSTRGGHTETGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSSNQNQSPLRQLDNGVNGREEDDDVEMLIPVSEGASDFDVNDCSRPLLDLASDQGQGFRQPYSGTNPGVRPSSRDGPCERCGIVHTAQIPDSCLEATLKTETSDDEALLLC", "length": 825, "header": "tr|A0AAA9SHS3-1|A0A3Q1LUU5_BOVIN Computationally mapped isoform of Low-density lipoprotein receptor-related protein 12 OS=Bos taurus OX=9913 GN=LRP12 PE=3 SV=1 CANONICAL=A0A3Q1LUU5-1" }, "locus": { "chromosome": "14", "start_pos": 60124356, "end_pos": 60077008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109832.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109832.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083452.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083452.1" } ] } }, { "isoform_ac": "E1BN03-1", "url": "https://www.uniprot.org/uniprotkb/E1BN03/entry", "sequence": { "sequence": "MARRWNTKESPRWRSALVLLFLAGVYGNRALAEHSENVHISGVSTACGETPEQIRAPSGIITSPGWPSEYPARINCSWFIRANPGEIITISFQDFDIQGSRRCSLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPAAWKCNNMDECGDSSDEEICAREANPPTSASFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTVCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDTAGASGGVTAPLPQKVPPTTAVEATVGASGSSSTQSTRGGHTETGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSSNQNQSPLRQLDNGVNGREEDDDVEMLIPVSEGASDFDVNDCSRPLLDLASDQGQGFRQPYSGTNPGVRPSSRDGPCERCGIVHTAQIPDSCLEATLKTETSDDEALLLC", "length": 859, "header": "tr|E1BN03-1|E1BN03_BOVIN Computationally mapped isoform of Low-density lipoprotein receptor-related protein 12 OS=Bos taurus OX=9913 GN=LRP12 PE=3 SV=2 CANONICAL=A0A3Q1LUU5-1" }, "locus": { "chromosome": "14", "start_pos": 60124356, "end_pos": 60035685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015304.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015304.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015304.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015304.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519993", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519993", "resource": "KEGG Pathway" }, { "id": "R-BTA-975634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "resource": "Reactome", "description": "Retinoid metabolism and transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YQ02-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "LRP12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPWGSAEGFPAWRSAQLLLLVVSCCGNSLHSIQLHNYSGCSWNVLQLILIYSCYLCEGRVEGNGALAEHSENVHISGVSTACGDIPEQIRSPSGTITSPGWPSEYPARINCSWYIHANPGEIITISFQDFDVQGSRRCSSDWLTIGSYKNIEGYRACGSSIPSPYISSQDHVWIRFHSDDSISRKGFRLAYFAGKSDEPNCDCDQFHCANGKCIPESWKCNNMDECGDNSDEEICAKANPPTISSFQPCASNQFQCLSRFTKLYTCLPESLKCDGNIDCLDLGDEIDCEVPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGFGDYVKIYDGLEENPRRLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQRDEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETHLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPITGRSSNIWNRIFNFARSRHSGSLALVSADGDDVASQSTSRDAERSNTHRSLFSVESDDTDTENERRDTAGAVGGVAATLPQKVPPATAIEATVGACGSSSAQSGSGGNTDSGREVTSIEPPGTSPARHQLTSALSRMTQGLRWVRFTLGRSSSVNQNQSPLRQLDNGVSGREEDDDVEMLIPVSDVASDFDMNDCSRPLLDLSSDQEPGLRQPYSATHHGVRSCNRDGPCESCGIVHTAQIPDTCLEATVKNETSDDEALLLC", "length": 893 }, "evidence": [ { "id": "A0A3Q1LUU5", "url": "https://omabrowser.org/oma/group/A0A3Q1LUU5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZCF7-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "Lrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARRWSTKESPRRGSAWLLLFLAGVYGNGALAELSENVHISGVSTACGETPEQIRGPTGIITSPGWPSDYPAKINCSWLIRANPGEIITISFQDFDIQGSRRCTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGKSEEPHCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCVQDAHPPTTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEESCPVIVPTRVITAAVIGSLVCGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFPSIRLPMTGRSRNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRETERSHPHRSLFSAESDDTDTENERRDTAGASGGVAAPLPQKVPPTTAVEATVGTGGNSSAQSTRGGHADGREVSSVEAPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSTNQNRSPLRQLDTGVSGREDDDDVEMLIPVSDGASDIDANECSRPLLDLASDQVQGFRQPHSSGNPGARTSNRDGPCERCGIVHTAQIPDTCLEAAVKTEACDDEALLLC", "length": 858 }, "evidence": [ { "id": "A0A3Q1LUU5", "url": "https://omabrowser.org/oma/group/A0A3Q1LUU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BUJ9-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "Lrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARRWSTKESQRRGSAWLLLFLAGVYGNGALAELSENVHISGVSTACGESPEQIRAPSGIITSPGWPSDYPAQVNCSWLIRANPGEIITISFQDFDIQGSRRCTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGKSEQPDCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCASDAHPPTTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMTGRSSNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRETERSRPHRSLFSVESDDTDTENERRDTAGASGGVAAPLPQKVPPTTAVEATVGSGGNSSAQSTRGGHADGREVSSVEAPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSTTQNRSPLRQLDTAVSGREDDDDVEMLIPVSDGASDIDANDCSRPLLDLASDQVQGFRQPHSAGNPGVRTSNRDGPCERCGIVHTAQIPDTCLEATVKTETSDDEALLLC", "length": 858 }, "evidence": [ { "id": "A0A3Q1LUU5", "url": "https://omabrowser.org/oma/group/A0A3Q1LUU5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y561-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "LRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACRWSTKESPRWRSALLLLFLAGVYGNGALAEHSENVHISGVSTACGETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRACGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSVRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDMAGASGGVAAPLPQKVPPTTAVEATVGACASSSTQSTRGGHADNGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSLSQNQSPLRQLDNGVSGREDDDDVEMLIPISDGSSDFDVNDCSRPLLDLASDQGQGLRQPYNATNPGVRPSNRDGPCERCGIVHTAQIPDTCLEVTLKNETSDDEALLLC", "length": 859 }, "evidence": [ { "id": "A0A3Q1LUU5", "url": "https://omabrowser.org/oma/group/A0A3Q1LUU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LUU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUU5" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 140, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LPC5-1", "uniprot_ac": "A0A3Q1LPC5", "uniprot_id": "A0A3Q1LPC5_BOVIN", "mass": { "chemical_mass": 149512.0, "monoisotopic_mass": 149512.0 }, "refseq": {}, "gene_names": [ { "name": "KIF16B", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ] } ], "protein_names": [ { "name": "Kinesin-like protein KIF16B", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LK85", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK85#function" }, { "database": "UniProtKB", "id": "ARBA00054846", "url": "https://www.uniprot.org/uniprotkb/ARBA00054846#function" }, { "database": "UniProtKB", "id": "A0A3Q1LQE5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQE5#function" }, { "database": "UniProtKB", "id": "A0A3Q1M1N5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1N5#function" }, { "database": "UniProtKB", "id": "A0A3Q1NNQ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNQ3#function" }, { "database": "UniProtKB", "id": "A0AAA9S4B2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4B2#function" }, { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KIF16B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5", "locus": { "chromosome": "13", "start_pos": 10070035, "end_pos": 10418992, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000939", "url": "https://www.ensembl.org/id/ENSBTAG00000000939" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000939", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000939", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01365", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01365", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06874", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06874", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532276", "url": "https://www.ncbi.nlm.nih.gov/gene/532276", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HWHGAQQ", "url": "https://omabrowser.org/oma/group/HWHGAQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LK85", "url": "https://www.orthodb.org/?gene=A0A3Q1LK85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNQ3", "url": "https://www.orthodb.org/?gene=A0A3Q1LNQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPC5", "url": "https://www.orthodb.org/?gene=A0A3Q1LPC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQE5", "url": "https://www.orthodb.org/?gene=A0A3Q1LQE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1N5", "url": "https://www.orthodb.org/?gene=A0A3Q1M1N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NNQ3", "url": "https://www.orthodb.org/?gene=A0A3Q1NNQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X690", "url": "https://www.orthodb.org/?gene=G3X690", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47117:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47117:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LK85", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK85-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNQ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQE5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1N5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NNQ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NNQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4B2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4B2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJJ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X690", "url": "https://www.uniprot.org/uniprotkb/G3X690", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X690-1", "url": "https://www.uniprot.org/uniprotkb/G3X690-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTTVMFPEEGRCVCREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGFFPIKGPICLRLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1306, "header": "tr|A0A3Q1LPC5-1|A0A3Q1LPC5_BOVIN Isoform 1 of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=2 CANONICAL=A0A3Q1LPC5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK85-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK85/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYEITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1203, "header": "tr|A0A3Q1LK85-1|A0A3Q1LPC5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=2 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10071039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086783.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086783.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056922.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056922.2" } ] } }, { "isoform_ac": "A0A3Q1LNQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ3/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1267, "header": "tr|A0A3Q1LNQ3-1|A0A3Q1LNQ3_BOVIN Computationally mapped isoform of Kinesin family member 16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=2 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10071039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081698.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081698.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061664.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061664.2" } ] } }, { "isoform_ac": "A0A3Q1LPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5/entry", "sequence": { "sequence": "MGTTVMFPEEGRCVCREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGFFPIKGPICLRLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1306, "header": "tr|A0A3Q1LPC5-1|A0A3Q1LPC5_BOVIN Isoform 1 of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=2 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10418898, "end_pos": 10071039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074146.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074146.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058862.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058862.2" } ] } }, { "isoform_ac": "A0A3Q1LQE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQE5/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGFFPIKGPICLRLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1306, "header": "tr|A0A3Q1LQE5-1|A0A3Q1LQE5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=1 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10071039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069934.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069934.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062398.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062398.1" } ] } }, { "isoform_ac": "A0A3Q1M1N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1N5/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYEKSCPAPLLPRDITDAPGQEESGEVDQNHHWSLPVTRIIPGPSARCSAPDWGANQRGPQPSEDEPSHSSSCNRGNSQPERLNPTETPPLSKSSTSGAGHTHGESESLSEPTSPQGGPSPGLTSSWTWLQHISQEVSVDSRGEQTWRSQLLCFILSERVPRASVPPAALASKLCWEEAAAGAVSSSESLMTVEPEGSRGLGFIYQWVSDLYKDTRSHLLRTGTEAVGQAQLVGSLCDPSRLASQAATFLTRLPILKLSPLYRLLETGGAAAEALSLPKESQVGSRDEAGAVGRAGSLVPYRALGWPTGPMATEFPGSSLSSVSCLELEGARRGSVFKQTLVQFPDQMLKLQECPLTDFLELVAGSLPELWGNADVPQGMYWLAVANCAEPAPRPACLLLFSSSLYALVLDPPGSVGVFHTLPLSGLQEIQVGFGGQSVRLLGSAESLLLTIFTYNKNLCQQICRDLLYVLASASEAAACAEHPLFREDLVQVSLDWKAEIPDLVLANGVRLSSRFQNTLVDLIYFLHGNLDAGAPSLAEAQLLLYTTVRVEGDSGQGPCQSLILLNTHVALVREDRVFYPRSPALSSPPPGTRFDVVRCRALREFRCLVIPETKTSSTLELVFLQNLRHQSDSGSGASRRPQEAQKVQPCTSTLDLQGGGDVVPEITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1917, "header": "tr|A0A3Q1M1N5-1|A0A3Q1M1N5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=2 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10071039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086620.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086620.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063645.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063645.2" } ] } }, { "isoform_ac": "A0A3Q1NNQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NNQ3/entry", "sequence": { "sequence": "MSGSYKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGFFPIKGPICLRLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1273, "header": "tr|A0A3Q1NNQ3-1|A0A3Q1LPC5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=2 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10334473, "end_pos": 10071039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085063.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085063.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074533.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074533.2" } ] } }, { "isoform_ac": "A0AAA9S4B2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4B2/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYEKSCPAPLLPRDITDAPGQEESGEVDQNHHWSLPVTRIIPGPSARCSAPDWGANQRGPQPSEDEPSHSSSCNRGNSQPERLNPTETPPLSKSSTSGAGHTHGESESLSEPTSPQGGPSPGLTSSWTWLQHISQEVSVDSRGEQTWRSQLLCFILSERVPRASVPPAALASKLCWEEAAAGAVSSSESLMTVEPEGSRGLGFIYQWVSDLYKDTRSHLLRTGTEAVGQAQLVGSLCDPSRLASQAATFLTRLPILKLSPLYRLLETGGAAAEALSLPKESQVGSRDEAGAVGRAGSLVPYRALGWPTGPMATEFPGSSLSSVSCLELEGARRGSVFKQTLVQFPDQMLKLQECPLTDFLELVAGSLPELWGNADVPQGMYWLAVANCAEPAPRPACLLLFSSSLYALVLDPPGSVGVFHTLPLSGLQEIQVGFGGQSVRLLGSAESLLLTIFTYNKNLCQQICRDLLYVLASASEAAACAEHPLFREDLVQVSLDWKAEIPDLVLANGVRLSSRFQNTLVDLIYFLHGNLDAGAPSLAEAQLLLYTTVRVEGDSGQGPCQSLILLNTHVALVREDRVFYPRSPALSSPPPGTRFDVVRCRALREFRCLVIPETKTSSTLELVFLQNLRHQSDSGSGASRRPQEAQKVQPCTSTLDLQGGGDVVPERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLERYLRDFFSVMLQSATSPLHIDKVGLTLSKHTVCEFSPFFKKGVFDYSSHGTG", "length": 1958, "header": "tr|A0AAA9S4B2-1|A0A3Q1LPC5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=1 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10071039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116117.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116117.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079974.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079974.1" } ] } }, { "isoform_ac": "A0AAA9SHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SHB8/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLEKIQNN", "length": 1248, "header": "tr|A0AAA9SHB8-1|A0A3Q1LPC5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=1 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10094311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114448.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114448.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084732.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084732.1" } ] } }, { "isoform_ac": "A0AAA9SJJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJJ6/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGFFPIKGPICLRLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYEKSCPAPLLPRDITDAPGQEESGEVDQNHHWSLPVTRIIPGPSARCSAPDWGANQRGPQPSEDEPSHSSSCNRGNSQPERLNPTETPPLSKSSTSGAGHTHGESESLSEPTSPQGGPSPGLTSSWTWLQHISQEVSVDSRGEQTWRSQLLCFILSERVPRASVPPAALASKLCWEEAAAGAVSSSESLMTVEPEGSRGLGFIYQWVSDLYKDTRSHLLRTGTEAVGQAQLVGSLCDPSRLASQAATFLTRLPILKLSPLYRLLETGGAAAEALSLPKESQVGSRDEAGAVGRAGSLVPYRALGWPTGPMATEFPGSSLSSVSCLELEGARRGSVFKQTLVQFPDQMLKLQECPLTDFLELVAGSLPELWGNADVPQGMYWLAVANCAEPAPRPACLLLFSSSLYALVLDPPGSVGVFHTLPLSGLQEIQVGFGGQSVRLLGSAESLLLTIFTYNKNLCQQICRDLLYVLASASEAAACAEHPLFREDLVQVSLDWKAEIPDLVLANGVRLSSRFQNTLVDLIYFLHGNLDAGAPSLAEAQLLLYTTVRVEGDSGQGPCQSLILLNTHVALVREDRVFYPRSPALSSPPPGTRFDVVRCRALREFRCLVIPETKTSSTLELVFLQNLRHQSDSGSGASRRPQEAQKVQPCTSTLDLQGGGDVVPEVWKLTFNSRDEALWLTSHLTRL", "length": 1789, "header": "tr|A0AAA9SJJ6-1|A0A3Q1LPC5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=1 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10160474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107833.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107833.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086460.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086460.1" } ] } }, { "isoform_ac": "G3X690-1", "url": "https://www.uniprot.org/uniprotkb/G3X690/entry", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTESPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGDSGDSGLIPRICEGLFSQINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPSETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDASNPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIYDDLLSTGMILYHLKEGQTHVGREDASTEQDIVLHGLDLESEHCIFENVGGTVTLIPLSGSQCSVNGVQITEATHLNQGAMILLGRTNMFRFNHPKEAAKLREKRKSGLLSSLSLSMSDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAALERMQQEVETQRQETEMAQRQIRKQEESLKRRSSHLESTLKDLLAEKERFEEARQREQQETELQKKKQEEERFLRVQEELQRLQELNSHEKAEKVQIFQELERLKREKEEQYAKLEQEKQRLEEQEREQVLRVAQLEAQLRAKQQLLQPPQRGEAQRLAEERRHLEGIRTALLQAREAGAEAGGDSPELEQAQLRFLEFKRRQLATLANMEKDLLQQKDLLKREVEEDREFLRERLPSGSQEELRGSEKEEEGGADVLWAAGAVEGMQPAEGRLQCKKRQLQDLLQQHLPRLSEEKQRVREILDRGPLDLDNTLYLVENEMEEKEEQLAQYQASASQLQKLQATFEFTANVARQEEKVRRKEKEILESREQQQREALERAVARLERRHSALQRRCARAAGGEQAGQEALEKDRERLEHEIQQLKLKICEVDGVQKGHRGTLEGKPAASSFPSSAEKSHPVPLMDERISAYIEEEVQRRLQGLHRVVGDGCREPADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDEHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKHAELATLEFPPKKLFGNKDERVIAERRSQLE", "length": 1243, "header": "tr|G3X690-1|A0A3Q1LPC5_BOVIN Computationally mapped isoform of Kinesin-like protein KIF16B OS=Bos taurus OX=9913 GN=KIF16B PE=3 SV=3 CANONICAL=A0A3Q1LPC5-1" }, "locus": { "chromosome": "13", "start_pos": 10377437, "end_pos": 10099159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001242.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001242.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001242.7", "url": "https://www.ensembl.org/id/ENSBTAP00000001242.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L5F9-1", "protein_name": "Kinesin family member 16B", "gene_name": "Kif16b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQETVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEALFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYSDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDAEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLHQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGREDASTEQDIVLHGLDLESEHCVFENAGGTVTLIPLSGSQCSVNGVQIVDATQLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSCENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETRRKETEIVQRQIRKQEESLKRRSFHIENKLKDLLAEKERFEEERLREQQGLEQQKRQEEDSFFRIREELRRLQELNSHEQAEKGQPLQDLDWLHREQDAQSAKLQLEKRRLEEQEKEQVLRVAHLEEQLRKRQDTAPLLCPGEAQQAQEERRELEGIRGALLQAKEIRAGGDHTFRGELERAQQYFLEFKRRQLVKLATLEKDLVQQKDRLSKEVQEEKEALEHVKCEAGEEPSLLATDNCNILCGPQDLDKIKTAESRLQSKEHQLQDLLQNHLPALLEEKQRVLEILDCGVLGLDNILYHVEKEMEEKEEQITQYQANASQLQQLQATVQFTANVARQEEKVRRKEKEILESQEKQQREALEQAVAKLEQRHSALKRRSTLDLEIQEQRQKLGSLHSSEWPGLQASLEANGERLQMDPARIEHEIHELKQKICEVDGVQRPHHGTLEGKAALSSLPPSAENSHLAPLMDARISAYIEEEVQRRLHDLHRVISDASHAPAELKSNEELHNGATQRKLKYELCQDLLGVLMSGSEAAAYTNHPLLHQDLVQLSLDLKAEIPVLALANGVQLSSNFQTTLVDMVYFLHGNMEASVPSLAEVQLLLYTTVRLESEAGCALCRSFILLNTHVALLREDHVFYPRTGSLITLPPHGRFDVITCQALSEFRCVIVPEKDNVSKVELVFLRKHGLPLNRGSGLSEQSQVASSSQMVTPLCLEDGQNQTLDIWKLTFNSQDEALWLISYLTRL", "length": 1385 }, "evidence": [ { "id": "A0A3Q1LPC5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B1AVY7-1", "protein_name": "Kinesin-like protein KIF16B", "gene_name": "Kif16b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEALFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYSDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDAEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLHQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGREDASTEQDIVLHGLDLESEHCVFENAGGTVTLIPLRGSQCSVNGVQIVDATQLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSCENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETRRKETEIVQRQIRKQEESLKRRSFHIENKLKDLLAEKERFEEERLREQQGLEQQRRQEEESLFRIREELRKLQELNSHEQAEKVQIFQELDRLHQEQNAQSAKLRLEKRRLEEEEKEQVQRVAHLEEQLRKRQDTAPLLCPGEAQRAQEEKRELESIREALLQAKEMRAGGDHTCRDELERAQQYFLEFKRRQLVKLASLEKDLVQQKDLLSKEVQEEKVALEHVKCDAGGDPSFLATDDGNILGGPPDLDKIKTAETRLQSREHQLQDLLQNHLPALLEEKQRVLDALDSGVLGLDTTLCQVEKEVGEKEEQIAQYQANASQLQQLRATFEFTANVARQEEKVRRKEKEILESQEKQQREALEQAVAKLEQRRSALQRCSTLDLEIQEQRQKLGSLHTSEWSGWQASLETDGEALEMDPARLEHEIHQLKQKICEVDGVQRPHHGILEGQAVLSSLPPSGGNSHLAPLMDARISAYIEEEVQRRLHDLHRAIGDANHTPADVMKSNEELHNGTTQRKLKYERMYSRSLGTNRDDLKDPIKISIPRYVLCGQGKDEHFEFEVKISVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVVAERRTHLEKYLREFFSVMLQSETSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG", "length": 1312 }, "evidence": [ { "id": "A0A3Q1LPC5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96L93-1", "protein_name": "Kinesin-like protein KIF16B", "gene_name": "KIF16B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDAHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVIAERRSHLEKYLRDFFSVMLQSATSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG", "length": 1317 }, "evidence": [ { "id": "A0A3Q1LPC5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" }, { "name": "vesicle transport along microtubule", "id": "GO:0047496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047496", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1145, "end_pos": 1147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LTU2-1", "uniprot_ac": "A0A3Q1LTU2", "uniprot_id": "A0A3Q1LTU2_BOVIN", "mass": { "chemical_mass": 36869.0, "monoisotopic_mass": 36869.0 }, "refseq": { "ac": "XP_005217172", "name": "peroxisome biogenesis factor 10 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217172" }, "gene_names": [ { "name": "PEX10", "type": 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The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane. PEX10 also regulates PEX5 recycling by acting as a E3 ubiquitin-protein ligase. 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taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PEX10", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2", "locus": { "chromosome": "16", "start_pos": 50446716, "end_pos": 50437111, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009309", "url": "https://www.ensembl.org/id/ENSBTAG00000009309" } ] } } ], "crossref": [ { "id": "A0A3Q1LTU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LTU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009309", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009309", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16527", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16527", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614539", "url": "https://www.ncbi.nlm.nih.gov/gene/614539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YCDVVQL", "url": "https://omabrowser.org/oma/group/YCDVVQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LTU2", "url": "https://www.orthodb.org/?gene=A0A3Q1LTU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M343", "url": "https://www.orthodb.org/?gene=A0A3Q1M343", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23350", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23350", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23350:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23350:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04757", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04757", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8866654", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866654", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005217172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M343", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M343", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M343-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M343-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNH0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNH0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDW3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDW3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAVASPPEVVRAAQKDDYYRGGLRSAAGGALHNLAGAKKWLEWRREVELVSDLAYFGLTTLAGYQTLGEEYVSVVQVGPSQRHVPSRLRRGILVALHTVLPYLLDKALLHLEHELQATGDGTWPLRGSLAPSSQSGMRRWVHRCTAGLTEQQQGVLLRAVSALKQGLGCLQRLHVAWFYIHGAFYHLAKRFTGITYLRVRRPLAEDPRVRASYQLLGLVSLLHLALAAGLQLYGFQQRQRARREWRLQRGLSHRRNHAEERAVSRNPLCTLCLEERRHSTATPCGHLFCWECITHWSDTKTECPLCREKFLPQKLVYLRHYR", "length": 324, "header": "tr|A0A3Q1LTU2-1|A0A3Q1LTU2_BOVIN Isoform 1 of Peroxisome biogenesis factor 10 OS=Bos taurus OX=9913 GN=PEX10 PE=3 SV=1 CANONICAL=A0A3Q1LTU2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2/entry", "sequence": { "sequence": "MASAVASPPEVVRAAQKDDYYRGGLRSAAGGALHNLAGAKKWLEWRREVELVSDLAYFGLTTLAGYQTLGEEYVSVVQVGPSQRHVPSRLRRGILVALHTVLPYLLDKALLHLEHELQATGDGTWPLRGSLAPSSQSGMRRWVHRCTAGLTEQQQGVLLRAVSALKQGLGCLQRLHVAWFYIHGAFYHLAKRFTGITYLRVRRPLAEDPRVRASYQLLGLVSLLHLALAAGLQLYGFQQRQRARREWRLQRGLSHRRNHAEERAVSRNPLCTLCLEERRHSTATPCGHLFCWECITHWSDTKTECPLCREKFLPQKLVYLRHYR", "length": 324, "header": "tr|A0A3Q1LTU2-1|A0A3Q1LTU2_BOVIN Isoform 1 of Peroxisome biogenesis factor 10 OS=Bos taurus OX=9913 GN=PEX10 PE=3 SV=1 CANONICAL=A0A3Q1LTU2-1" }, "locus": { "chromosome": "16", "start_pos": 50441455, "end_pos": 50437248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083916.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083916.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060516.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060516.1" } ] } }, { "isoform_ac": "A0A3Q1M343-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M343/entry", "sequence": { "sequence": "MASAVASPPEVVRAAQKDDYYRGGLRSAAGGALHNLAGAKKWLEWRREVELVSDLAYFGLTTLAGYQTLGEEYVSVVQVGPSQRHVPSRLRRGILVALHTVLPYLLDKALLHLEHELQATGDGTWPLRGSLAPSSQSGMRRWVHRCTAGLTEQQQGVLLRAVSALKQGLGCLQRLHVAWFYIHGAFYHLAKRFTGITYLRVRRPLAEDPRVRASYQLLGLVSLLHLALAAGLQLYGFQQRQRARREWRLQRGLSHRRNHAEERAVSRNPLCTLCLEERRHSTATPCGHLFCWECITHWSDTKALKSNHGG", "length": 310, "header": "tr|A0A3Q1M343-1|A0A3Q1M343_BOVIN Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=PEX10 PE=3 SV=2 CANONICAL=A0A3Q1LTU2-1" }, "locus": { "chromosome": "16", "start_pos": 50443011, "end_pos": 50437248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082804.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082804.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067889.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067889.2" } ] } }, { "isoform_ac": "A0AAA9SNH0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNH0/entry", "sequence": { "sequence": "MASAVASPPEVVRAAQKDDYYRGGLRSAAGGALHNLAGYQTLGEEYVSVVQVGPSQRHVPSRLRRGILVALHTVLPYLLDKALLHLEHELQATGDGTWPLRGSLAPSSQSGMRRWVHRCTAGLTEQQQGVLLRAVSALKQGLGCLQRLHVAWFYIHGAFYHLAKRFTGITYLRVRRPLAEDPRVRASYQLLGLVSLLHLALAAGLQLYGFQQRQRARREWRLQRGLSHRRNHAEERAVSRNPLCTLCLEERRHSTATPCGHLFCWECITHWSDTKTECPLCREKFLPQKLVYLRHYR", "length": 297, "header": "tr|A0AAA9SNH0-1|A0A3Q1LTU2_BOVIN Computationally mapped isoform of Peroxisome biogenesis factor 10 OS=Bos taurus OX=9913 GN=PEX10 PE=3 SV=1 CANONICAL=A0A3Q1LTU2-1" }, "locus": { "chromosome": "16", "start_pos": 50441455, "end_pos": 50437248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129907.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129907.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087873.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087873.1" } ] } }, { "isoform_ac": "A0AAA9TDW3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW3/entry", "sequence": { "sequence": "MASAVASPPEVVRAAQKDDYYRGGLRSAAGGALHNLAGAKKWLEWRREVELVSDLAYFGLTTLAGYQTLGEEYVSVVQVGPSQRHVPSRLRRGILVALHTVLPYLLDKALLHLEHELQATGDGTWPLRGSLAPSSQSGMRRWVHRCTAGLTEQQQGVLLRAVSALKQGLGCLQRLHVAWFYIHGAFYHLAKRFTGITYLRVRRPLAEDPRVRASYQLLGLVSLLHLALAAGLQLYGFQQRQRARREWRLQRGLSHRRNHAEERAVSRNPLCTLCLEERRHSTATPCGHLFCWECITHWSDTKNSMMKYITRMGQNTGTLKASKKVHTMATKMPLVAACLWKERNPSTGRHET", "length": 352, "header": "tr|A0AAA9TDW3-1|A0A3Q1LTU2_BOVIN Computationally mapped isoform of Peroxisome biogenesis factor 10 OS=Bos taurus OX=9913 GN=PEX10 PE=3 SV=1 CANONICAL=A0A3Q1LTU2-1" }, "locus": { "chromosome": "16", "start_pos": 50445740, "end_pos": 50437248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104203.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104203.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095091.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095091.1" } ] } }, { "isoform_ac": "A0AAA9TXY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXY8/entry", "sequence": { "sequence": "MASAVASPPEVVRAAQKDDYYRGGLRSAAGGALHNLAGAKKWLEWRREVELVSDLAYFGLTTLAAEPVVQEGSQHCALPQGVGCYQTLGEEYVSVVQVGPSQRHVPSRLRRGILVALHTVLPYLLDKALLHLEHELQATGDGTWPLRGSLAPSSQSGMRRWVHRCTAGLTEQQQGVLLRAVSALKQGLGCLQRLHVAWFYIHGAFYHLAKRFTGITYLRVRRPLAEDPRVRASYQLLGLVSLLHLALAAGLQLYGFQQRQRARREWRLQRGLSHRRNHAEERAVSRNPLCTLCLEERRHSTATPCGHLFCWECITHWSDTKTECPLCREKFLPQKLVYLRHYR", "length": 343, "header": "tr|A0AAA9TXY8-1|A0A3Q1LTU2_BOVIN Computationally mapped isoform of Peroxisome biogenesis factor 10 OS=Bos taurus OX=9913 GN=PEX10 PE=3 SV=1 CANONICAL=A0A3Q1LTU2-1" }, "locus": { "chromosome": "16", "start_pos": 50441455, "end_pos": 50437248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108133.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108133.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103523.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103523.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-8866654", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866654", "resource": "Reactome", "description": "E3 ubiquitin ligases ubiquitinate target proteins" }, { "id": "R-BTA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AMG1-1", "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "PEX10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALTAASPPEVVRAAQKDDYYRGGLRSAAGDALHSLAGAKKWLEWRRELELVSDVAYFGLTTLAGYQTLGEEYVSVVQVDPSQSRVPSRLRRGILVALHTVLPYVLDKALLHLEHELQVAGDSTRPTQGSLAPTARSQSAPRRWVRRRTATLTEQQQRALLQAAGMLRQVLGCLRRLHVAWFYIHGAFYHLAKRFTGITYLRVRRPPAEDPRVRTGYRLLGLLSLLHLALSAGLQLYSSRQKQRARQEWKLHRGLSHRRSHVDERVVSTASLCTLCLEERRHATATPCGHLFCWECITHWSDTKAECPLCREKFLPQKLVYLRHYR", "length": 326 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZC97-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "PEX10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALGPAGPARLVRCGQKDELYRSGLRSGAGTALHGIAGAKKWLEWRREIELLSDVAYFALTTLSGYQTLGEEYVNIVQVDSTKKRVPSFLRRAIFVSLHTIVPYYLEKGLQHLEHELQIEDDGARTLQSNPALGLSSRTLIRNWIQKQVRELTEQQKKTILQVVYILKQSIPLLHRLHLAVFYIHGTFYHLSKRIAGIRYLHFGGLQGEDQSIRSSYKFLGIISLFHLLLTIGVQIYSFQQKQRARQEWKLHRNLALQKNTIKEGTTGRQSRCTLCLEERRHATATPCGHLFCWECITEWCNTRTECPLCREKFHPQKLIYLRHYQL", "length": 327 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B1AUE5-1", "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "Pex10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARAGAPEVIRAAQKDEYYLGGLRSAAGEALHSLAGAKKWLEWRKEIELLSDIAYFGLTTIAGYQTLGEEYVGIIQVDPSQQRVPSRLRRAALVALHAVLPYLLDKALLPLEQELQADGDAPRASQGSLLPGGRSRSGARRWVRHHAATLTEQQRKALQRAVFILRQGFACLHRLHVAWFYIHGTFYHLAKRLAGITYLRTRRLPGEDQKARTSYGLLGLISLLHLVLSMGLRLYSFRQKQRARKEWRLHRNLSHRRSSLEDRAVCRTPLCTLCLEERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKLVYLRHYR", "length": 324 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZC81-1", "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "Pex10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQAGPPEVIRAAQKDEYYLGGLRSAAGGALHSLAGAKKWLEWRKEIELLSDIAYFGLTTIAGYQTLGEEYVGIIQVDPSRQRVPSRLRRGVLVALHAVLPYLLDKALLPLEQELQAEGDGTRASQGSLLPGGRSRSGARRWVRHHAATLTEQQRRALQRAVFILRQGFACLHRLHVAWFYIHGTFYHLAKRLAGITYLRTRRLPGEDLRACTSYRLLGLISLLHLALSLGLQLYSFRQKQRARKEWRLHRNLSHRRSSLEDRAVCRAPLCTLCLEERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKLVYLRHYR", "length": 324 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I1X6-1", "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "Pex10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALAGAPEVIRAAQKDDYYLGGLRSAAGSALHSLAGAKKWLEWRKEIELLSDIAYFGLTTIAGYQTLGEEYVGIIQVDPSQQHVPSRLRRGVLVALHAVLPYLLDKALLPLEQELQADGDGTRASQGSLLPGGRSRSGARRWVRHHAATLSEQQRRTLQRTIFILRQGLACLHRFHVAWFYIHGAFYHLAKRLAGISYLRTRRLPGEDLRARTSYRLLGLISLLHLALSMGLQLYSFRQKQRARKEWRLHRNLSHRRSSLEDRAVCRAPLCTLCLEERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKLVYLRHYR", "length": 324 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60683-1", "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "PEX10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPAAASPPEVIRAAQKDEYYRGGLRSAAGGALHSLAGARKWLEWRKEVELLSDVAYFGLTTLAGYQTLGEEYVSIIQVDPSRIHVPSSLRRGVLVTLHAVLPYLLDKALLPLEQELQADPDSGRPLQGSLGPGGRGCSGARRWMRHHTATLTEQQRRALLRAVFVLRQGLACLQRLHVAWFYIHGVFYHLAKRLTGITYLRVRSLPGEDLRARVSYRLLGVISLLHLVLSMGLQLYGFRQRQRARKEWRLHRGLSHRRASLEERAVSRNPLCTLCLEERRHPTATPCGHLFCWECITAWCSSKAECPLCREKFPPQKLIYLRHYR", "length": 326 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q05568-1", "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "PEX10", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKNDNKLQKEALMRLSQLRFPFADAPSIVQAHQKDEQIQGLLIMKVTELCKLIKSQLFVNSYPKELSIFAKLLYLLFTTGRRGRTLGEEYVDLTYTNRKGTRLAGRLKMIVFAFAYPLCPYFITKLYKKIMKNNKESKIEDTESVAAFCKGLLDFILDVHMTLFYFKGAFYSISKRIFGMRYVFKHILSKNEANFREEGSQKYKVLGYILLAQNVMKWYPVLTSTLGSWIYGRKRTNDSITRSSVGLQERSEHESIEGIPKESQLTHINLSDKNQLPFIPEASRKCILCLMNMSDPSCAPCGHLFCWSCLMSWCKERPECPLCRQHCQPQEILVLRQ", "length": 337 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9SYU4-1", "protein_name": "Peroxisome biogenesis factor 10", "gene_name": "PEX10", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRLNGDSGPGQDEPGSSGFHGGIRRFPLAAQPEIMRAAEKDDQYASFIHEACRDAFRHLFGTRIALAYQKEMKLLGQMLYYVLTTGSGQQTLGEEYCDIIQVAGPYGLSPTPARRALFILYQTAVPYIAERISTRAATQAVTFDESDEFFGDSHIHSPRMIDLPSSSQVETSTSVVSRLNDRLMRSWHRAIQRWPVVLPVAREVLQLVLRANLMLFYFEGFYYHISKRASGVRYVFIGKQLNQRPRYQILGVFLLIQLCILAAEGLRRSNLSSITSSIQQASIGSYQTSGGRGLPVLNEEGNLITSEAEKGNWSTSDSTSTEAVGKCTLCLSTRQHPTATPCGHVFCWSCIMEWCNEKQECPLCRTPNTHSSLVCLYHSDF", "length": 381 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W0D7-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Pex10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFRNARARQPEIVRSVQKDARYTNELAEDLSDVLRLTGPRNWIKYNQMCRLLAELSYHGFASANNLQTLGEEYTGIIQVDGNYKQIPSRLLQLIAIVLEFGGDSLFQRLMQKLDTYVANNDEIRTEIKPQLKKIIQRLRQSPSYVKALHKSLFYLDASKYQLSKRTTGINYVLIRHWLQPEFSLYGYKILGVITFLQVSVSLAISGWDAWREHKRQQLESIKQAGKNFLQRSSSTKDVDPNTPQCILCLEPRSDSSLTPCGHIFCWSCLLEWLEERDECPLCRESLKKSQVILLQNYA", "length": 299 }, "evidence": [ { "id": "A0A3Q1LTU2", "url": "https://omabrowser.org/oma/group/A0A3Q1LTU2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-8953917", "name": "PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMX2-1", "Q2TA10-1", "A0A3Q1LTU2-1" ], "evidence": [ { "id": "R-BTA-8953917", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8953917" } ] }, { "id": "R-BTA-8953946", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMX2-1", "Q2TA10-1", "A0A3Q1LTU2-1" ], "evidence": [ { "id": "R-BTA-8953946", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8953946" } ] }, { "id": "R-BTA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033235" } ] }, { "id": "R-BTA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033236" } ] }, { "id": "R-BTA-9033485", "name": "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMX2-1", "Q2TA10-1", "A0A3Q1LTU2-1" ], "evidence": [ { "id": "R-BTA-9033485", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033485" } ] }, { "id": "R-BTA-9033499", "name": "PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [ "R-BTA-9033107", "R-BTA-9033138" ], "enzyme_list": [ "A0A3Q1LTU2-1" ], "evidence": [ { "id": "R-BTA-9033499", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033499" } ] }, { "id": "R-BTA-9033514", "name": "Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LTU2-1", "O18778-1", "A0AAA9TIG7-1" ], "evidence": [ { "id": "R-BTA-9033514", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033514" } ] }, { "id": "R-BTA-9033516", "name": "PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LTU2-1" ], "evidence": [ { "id": "R-BTA-9033516", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033516" } ] }, { "id": "R-BTA-9033527", "name": "PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMX2-1", "Q2TA10-1", "A0A3Q1LTU2-1" ], "evidence": [ { "id": "R-BTA-9033527", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033527" } ] }, { "id": "R-BTA-9033533", "name": "PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LTU2-1" ], "evidence": [ { "id": "R-BTA-9033533", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033533" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-9033107", "participant_name": "PEX7 [cytosol]", "crossref": [ { "id": "ENSBTAP00000022338", "database": "ENSEMBL", "url": "" }, { "id": "NP_001070358.1", "database": "RefSeq", "url": "" }, { "id": "Q08DL6", "database": "UniProt", "url": "" }, { "id": "32764", "database": "VGNC", "url": "" }, { "id": "ENSBTAT00000022338", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAG00000016791", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-9033138", "participant_name": "ZFAND6 [cytosol]", "crossref": [ { "id": "XP_024837514.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAT00000066020", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAG00000012321", "database": "ENSEMBL", "url": "" }, { "id": "XP_024837515.1", "database": "RefSeq", "url": "" }, { "id": "107038", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000056063", "database": "ENSEMBL", "url": "" }, { "id": "NP_001029632.1", "database": "RefSeq", "url": "" }, { "id": "Q3SZY7", "database": "UniProt", "url": "" }, { "id": "XP_059735024.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8A5", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] } ] }, { "uniprot_ac": "A0A3Q1LQH8", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LS67", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] } ] }, { "uniprot_ac": "A0A3Q1LTU2", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LYY4", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] } ] }, { "uniprot_ac": "A0AAA9SAI8", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0AAA9SAI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAI8" } ] } ] }, { "uniprot_ac": "A0AAA9SC38", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] } ] }, { "uniprot_ac": "A0AAA9SND8", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] } ] }, { "uniprot_ac": "A0AAA9SXG3", "gene_name": "DAO", "activity": [ { "ec_number": "1.4.3.3", "activity": "D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + H2O2 + NH4(+).", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] }, { "ec_number": "1.4.3.3", "activity": "", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] } ] }, { "uniprot_ac": "A0AAA9TBR3", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] } ] }, { "uniprot_ac": "A0AAA9TIG7", "gene_name": "AGPS", "activity": [ { "ec_number": "2.5.1.26", "activity": "a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+).", "evidence": [ { "id": "A0AAA9TIG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIG7" } ] }, { "ec_number": "2.5.1.26", "activity": "", "evidence": [ { "id": "A0AAA9TIG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIG7" } ] } ] }, { "uniprot_ac": "A0AAA9TW47", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] } ] }, { "uniprot_ac": "A0AAA9TYP4", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] } ] }, { "uniprot_ac": "A0AAA9TZC7", "gene_name": "ECI2", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] } ] }, { "uniprot_ac": "F1MQP2", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] } ] }, { "uniprot_ac": "F1MV74", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] } ] }, { "uniprot_ac": "F1MVP8", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] } ] }, { "uniprot_ac": "F1MYR5", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] } ] }, { "uniprot_ac": "F6RWU6", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] } ] }, { "uniprot_ac": "O18778", "gene_name": "PHYH", "activity": [ { "ec_number": "1.14.11.18", "activity": "phytanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyphytanoyl-CoA + succinate + CO2.", "evidence": [ { "id": "O18778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18778" } ] }, { "ec_number": "1.14.11.18", "activity": "", "evidence": [ { "id": "O18778", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18778" } ] } ] }, { "uniprot_ac": "O19094", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] } ] }, { "uniprot_ac": "P00432", "gene_name": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5J8", "url": "https://www.uniprot.org/uniprotkb/F1N5J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5J8-1", "url": "https://www.uniprot.org/uniprotkb/F1N5J8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SAILNQLVHLEVLGSRTFFSYGTKTLYQNNEALQSKFFPPFPKVMLPANSFQGKVAFITGGGTGLGKGMTTCLSSLGAQCVIASRKIDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNAVSETIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLAIGKELIKAQKGASFLAITTIYAETGSGFVVPSASAKAGVEALNKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLAAFLCSDYASWINGAVIRFDGGEEVLISGEFNSLRKVTKDQWDIIEGLIRKTKGS", "length": 329, "header": "tr|A0A3Q1LNW7-1|A0A3Q1LNW7_BOVIN Isoform 1 of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Bos taurus OX=9913 GN=DECR1 PE=1 SV=1 CANONICAL=A0A3Q1LNW7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7/entry", "sequence": { "sequence": "SAILNQLVHLEVLGSRTFFSYGTKTLYQNNEALQSKFFPPFPKVMLPANSFQGKVAFITGGGTGLGKGMTTCLSSLGAQCVIASRKIDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNAVSETIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLAIGKELIKAQKGASFLAITTIYAETGSGFVVPSASAKAGVEALNKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLAAFLCSDYASWINGAVIRFDGGEEVLISGEFNSLRKVTKDQWDIIEGLIRKTKGS", "length": 329, "header": "tr|A0A3Q1LNW7-1|A0A3Q1LNW7_BOVIN Isoform 1 of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Bos taurus OX=9913 GN=DECR1 PE=1 SV=1 CANONICAL=A0A3Q1LNW7-1" }, "locus": { "chromosome": "14", "start_pos": 73715213, "end_pos": 73688905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087217.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087217.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058705.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058705.1" } ] } }, { "isoform_ac": "A0AAA9SPE3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPE3/entry", "sequence": { "sequence": "MKRGRHIQAALGRSPGFFSYGTKTLYQNNEALQSKFFPPFPKVMLPANSFQGKVAFITGGGTGLGKGMTTCLSSLGAQCVIASRKIDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNAVSETIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLAIGKELIKAQKGASFLAITTIYAETGSGFVVPSASAKAGVEALNKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLAAFLCSDYASWINGAVIRFDGGEEVLISGEFNSLRKVTKDQWDIIEGLIRKTKGS", "length": 328, "header": "tr|A0AAA9SPE3-1|A0A3Q1LNW7_BOVIN Computationally mapped isoform of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Bos taurus OX=9913 GN=DECR1 PE=1 SV=1 CANONICAL=A0A3Q1LNW7-1" }, "locus": { "chromosome": "14", "start_pos": 73731558, "end_pos": 73688905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118589.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118589.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084780.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084780.1" } ] } }, { "isoform_ac": "F1N5J8-1", "url": "https://www.uniprot.org/uniprotkb/F1N5J8/entry", "sequence": { "sequence": "MAVLNQLLFSWGRGSRRFFSYGTKTLYQNNEALQSKFFPPFPKVMLPANSFQGKVAFITGGGTGLGKGMTTCLSSLGAQCVIASRKIDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNAVSETIKVIGHPDIVINNAAGNFISPSERLSPNAWKTITDIVLNGTAFVTLAIGKELIKAQKGASFLAITTIYAETGSGFVVPSASAKAGVEALNKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGAFEKEMIDRIPCGRLGTVEELANLAAFLCSDYASWINGAVIRFDGGEEVLISGEFNSLRKVTKDQWDIIEGLIRKTKGS", "length": 329, "header": "tr|F1N5J8-1|A0A3Q1LNW7_BOVIN Computationally mapped isoform of 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial OS=Bos taurus OX=9913 GN=DECR1 PE=1 SV=1 CANONICAL=A0A3Q1LNW7-1" }, "locus": { "chromosome": "14", "start_pos": 73731800, "end_pos": 73688905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026202.5", "url": "https://www.ensembl.org/id/ENSBTAT00000026202.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026202.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026202.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-77288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77288", "resource": "Reactome", "description": "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids" } ], "orthologs": [ { "uniprot_canonical_ac": "Q16698-1", "protein_name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "gene_name": "DECR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLPARVFFTLGSRLPCGLAPRRFFSYGTKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKEQWDTIEELIRKTKGS", "length": 335 }, "evidence": [ { "id": "A0A3Q1LNW7", "url": "https://omabrowser.org/oma/group/A0A3Q1LNW7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64591-1", "protein_name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "gene_name": "Decr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLARAFFAGVSRLPCDPGPQRFFSFGTKTLYQSIDAPQSKFFPPILKPMLPPNAFQGKVAFITGGGTGLGKAMTTFLSSLGAQCVIASRNIDVLKATAEEITSKTGNKVYAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLSPNGWKTITDIVLNGTAYVTIEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGKFEKDMIERIPCGRLGTVEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDVIEGLIRKTKGS", "length": 335 }, "evidence": [ { "id": "A0A3Q1LNW7", "url": "https://omabrowser.org/oma/group/A0A3Q1LNW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CQ62-1", "protein_name": "2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial", "gene_name": "Decr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLGRAFFAGVSRLPCDPGPQRFFSFGTKTLYQSKDAPQSKFFQPVLKPMLPPDAFQGKVAFITGGGTGLGKAMTTFLSTLGAQCVIASRNIDVLKATAEEISSKTGNKVHAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLTPNGWKTITDIVLNGTAYVTLEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGRFEKEMIDRIPCGRLGTMEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDIIEGLIRKTKGS", "length": 335 }, "evidence": [ { "id": "A0A3Q1LNW7", "url": "https://omabrowser.org/oma/group/A0A3Q1LNW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" }, { "name": "2,4-dienoyl-CoA reductase (NADPH) activity", "id": "GO:0008670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008670", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" }, { "name": "NADPH binding", "id": "GO:0070402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070402", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" }, { "name": "catalytic complex", "id": "GO:1902494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902494", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "44912", "name": "", "equation": "(2E,4E)-hexadienoyl-CoA + NADPH + H(+) = (3E)-hexenoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LNW7-1" ], "evidence": [ { "id": "44912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44912" } ] }, { "id": "45912", "name": "", "equation": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LNW7-1" ], "evidence": [ { "id": "45912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45912" } ] }, { "id": "61892", "name": "", "equation": "a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LNW7-1" ], "evidence": [ { "id": "61892", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61892" } ] }, { "id": "R-BTA-109343", "name": "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-109990" ], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LNW7-1" ], "evidence": [ { "id": "R-BTA-109343", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-109343" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-109990", "participant_name": "2-trans-4-cis-decadienoyl-CoA [mitochondrial matrix]", "crossref": [ { "id": "137593", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LNW7", "gene_name": "DECR1", "activity": [ { "ec_number": "1.3.1.124", "activity": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "A0A3Q1LNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ] }, { "ec_number": "1.3.1.124", "activity": "", "evidence": [ { "id": "A0A3Q1LNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.3.1.124", "ec_name": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "1.3.1.124", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.124" }, { "id": "1.3.1.124", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.3.1.124" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 215, "end_pos": 217 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LNH0-1", "uniprot_ac": "A0A3Q1LNH0", "uniprot_id": "A0A3Q1LNH0_BOVIN", "mass": { "chemical_mass": 54034.0, "monoisotopic_mass": 54034.0 }, "refseq": { "ac": "XP_024846860", "name": "probable serine carboxypeptidase CPVL isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846860" }, "gene_names": [ { "name": "CPVL", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0" } ] }, { "name": "CPVL", "type": "synonym", "evidence": [ { "id": "XP_024846860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846860" } ] } ], "protein_names": [ { "name": "Carboxypeptidase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0/entry#names_and_taxonomy" } ] }, { "name": "3.4.16.-", "type": "synonym", "evidence": [ { "id": "A0A3Q1LNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0/entry#names_and_taxonomy" } ] }, { "name": "probable serine carboxypeptidase CPVL isoform X4", "type": "synonym", "evidence": [ { "id": "XP_024846860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846860" } ] } ], "function": [ { "annotation": "May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0#function" }, { "database": "UniProtKB", "id": "ARBA00055171", "url": "https://www.uniprot.org/uniprotkb/ARBA00055171#function" }, { "database": "UniProtKB", "id": "F1MX68", "url": "https://www.uniprot.org/uniprotkb/F1MX68#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPVL", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0", "locus": { "chromosome": "4", "start_pos": 67157925, "end_pos": 67030140, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007146", "url": "https://www.ensembl.org/id/ENSBTAG00000007146" } ] } } ], "crossref": [ { "id": "A0A3Q1LNH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007146", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007146", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534518", "url": "https://www.ncbi.nlm.nih.gov/gene/534518", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LIE2", "url": "https://www.orthodb.org/?gene=A0A3Q1LIE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNH0", "url": "https://www.orthodb.org/?gene=A0A3Q1LNH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MX68", "url": "https://www.orthodb.org/?gene=F1MX68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11802", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11802", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11802:SF472", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11802:SF472", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024846860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNH0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX68", "url": "https://www.uniprot.org/uniprotkb/F1MX68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX68-1", "url": "https://www.uniprot.org/uniprotkb/F1MX68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKALFLLVLLVLSPGADGLFRSLYRKGHVSSPRKGDPGQRLFLTPYIETGKLEEGRQLSLVPPFPGWNLTSYSGYITVNKTYNSNIFFWFFPAKIEPQNAPVVLWLQGGPGGSSMFGLFVEHGPYIVSKNMTLFARDFPWTITFSMLYVDNPVGTGFSFTDHVHGYAIDEDDVARNLYSALIQFFELFSDYRDNDFYVTGESYAGKYVPAIAHYIHILNPVTTMKINLKGIALGDAYFDPKSIIEGYPSFLFQIGLLDEQEKKYFQKQCNDCVKFIRQEKWLQAFELLDRLLDGGLISEPSYFQNVTGCSNYYNLLLCTEPEDQGYYGKFLSLPHVRQAIHVGNQTFSDGAKVEKYLREDTVKSVKPWLTEIMNNYKVLIYNGQLDVIVAASLTERSLMAMDWKGSQKYKKAGKKVWKILKSDPEVAGYVRQVGNFCQVIVRGGGHILPYDQPLRSFDMINRFIFGRGWDPY", "length": 473, "header": "tr|A0A3Q1LNH0-1|A0A3Q1LNH0_BOVIN Isoform 1 of Carboxypeptidase OS=Bos taurus OX=9913 GN=CPVL PE=3 SV=1 CANONICAL=A0A3Q1LNH0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIE2/entry", "sequence": { "sequence": "MWKALFLLVLLVLSPGADGLFRSLYRKGHVSSPRKGDPGQRLFLTPYIETGKLEEGRQLSLVPPFPGWNLTSYSGYITVNKTYNSNIFFWFFPAKIEPQNAPVVLWLQGGPGGSSMFGLFVEHGPYIVSKNMTLFARDFPWTITFSMLYVDNPVGTGFSFTDHVHGYAIDEDDVARNLYSALIQFFELFSDYRDNDFYVTGESYAGKYVPAIAHYIHILNPVTTMKINLKGIALGDAYFDPKSIIEGYPSFLFQIGLLDEQEKKYFQKQCNDCVKFIRQEKWLQAFEEPEDQGYYGKFLSLPHVRQAIHVGNQTFSDGAKVEKYLREDTVKSVKPWLTEIMNNYKVLIYNGQLDVIVAASLTERSLMAMDWKGSQKYKKAGKKVWKILKSDPEVAGYVRQVGNFCQVIVRGGGHILPYDQPLRSFDMINRFIFGRGWDPY", "length": 440, "header": "tr|A0A3Q1LIE2-1|A0A3Q1LNH0_BOVIN Computationally mapped isoform of Carboxypeptidase OS=Bos taurus OX=9913 GN=CPVL PE=3 SV=2 CANONICAL=A0A3Q1LNH0-1" }, "locus": { "chromosome": "4", "start_pos": 67157308, "end_pos": 67052449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084458.2", "url": 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67052449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086398.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086398.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061541.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061541.1" } ] } }, { "isoform_ac": "F1MX68-1", "url": "https://www.uniprot.org/uniprotkb/F1MX68/entry", "sequence": { "sequence": "MWKALFLLVLLVLSPGADGLFRSLYRKGHVSSPRKGDPGQRLFLTPYIETGKLEEGRQLSLVPPFPGWNLTSYSGYITVNKTYNSNIFFWFFPAKIEPQNAPVVLWLQGGPGGSSMFGLFVEHGPYIVSKNMTLFARDFPWTITFSMLYVDNPVGTGFSFTDHVHGYAIDEDDVARNLYSLSVLSDSATQRTVATRLLCPWNSPYKNTGSYAGKYVPAIAHYIHILNPVTTMKINLKGIALGDAYFDPKSIIEGYPSFLFQIGLLDEQEKKYFQKQCNDCVKFIRQEKWLQAFELLDRLLDGGLISEPSYFQNVTGCSNYYNLLLCTEPEDQGYYGKFLSLPHVRQAIHVGNQTFSDGAKVEKYLREDTVKSVKPWLTEIMNNYKVLIYNGQLDVIVAASLTERSLMAMDWKGSQKYKKAGKKVWKILKSDPEVAGYVRQVGNFCQVIVRGGGHILPYDQPLRSFDMINRFIFGRGWDPY", "length": 480, "header": "tr|F1MX68-1|A0A3Q1LNH0_BOVIN Computationally mapped isoform of Carboxypeptidase OS=Bos taurus OX=9913 GN=CPVL PE=3 SV=3 CANONICAL=A0A3Q1LNH0-1" }, "locus": { "chromosome": "4", "start_pos": 67157308, "end_pos": 67052449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009404.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009404.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009404.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009404.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type carboxypeptidase activity", "id": "GO:0004185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004185", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 69, "end_pos": 71 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LRP8-1", "uniprot_ac": "A0A3Q1LRP8", "uniprot_id": "A0A3Q1LRP8_BOVIN", "mass": { "chemical_mass": 23755.0, "monoisotopic_mass": 23755.0 }, "refseq": { "ac": "XP_024836220", "name": "coatomer subunit zeta-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836220" }, "gene_names": [ { "name": "COPZ2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LRP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRP8" } ] }, { "name": "COPZ2", "type": "synonym", "evidence": [ { "id": "XP_024836220", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836220" } ] } ], "protein_names": [ { "name": "Coatomer subunit zeta", "type": "recommended", "evidence": [ { "id": "A0A3Q1LRP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRP8/entry#names_and_taxonomy" } ] }, { "name": "coatomer subunit zeta-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024836220", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836220" } ] } ], "function": [ { "annotation": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.", "evidence": [ { "database": "UniProtKB", "id": "F1MXE6", "url": "https://www.uniprot.org/uniprotkb/F1MXE6#function" }, { "database": "UniProtKB", "id": "ARBA00045555", "url": "https://www.uniprot.org/uniprotkb/ARBA00045555#function" }, { "database": "UniProtKB", "id": "A0A3Q1LRP8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRP8#function" }, { "database": "UniProtKB", "id": "A0A3Q1LYE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYE2#function" }, { "database": "UniProtKB", "id": "A0AAA9TP39", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP39#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRP8", "url": 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"GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MNCLFES", "url": "https://omabrowser.org/oma/group/MNCLFES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LYE2", "url": "https://www.orthodb.org/?gene=A0A3Q1LYE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11043:SF4", "url": 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"Protein" ] }, { "id": "A0A3Q1LYE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP39", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP39-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXE6", "url": "https://www.uniprot.org/uniprotkb/F1MXE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXE6-1", "url": "https://www.uniprot.org/uniprotkb/F1MXE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"database": "Ensembl Transcript", "id": "ENSBTAT00000072788.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072788.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059849.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059849.2" } ] } }, { "isoform_ac": "A0A3Q1LYE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYE2/entry", "sequence": { "sequence": "MQRPEAWPRPHPGEGAAAAPTGGPAPPARAGEPAGLREPSLYTIKAVFILDNDGHRLLAKYYDDTFPSMKEQMAFEKNVFNKTSRTDSEIAFFGGMTIVYKSSIDLFLYVVGSSYENELMLMSVLTCLFESLNHVLRKNVEKRWLLENMDGAFLVVDEIVDGGVILESDPQQVIQKVNFRADDSGLTEHSVAQVLQSAKEQIKWSLLK", "length": 208, "header": "tr|A0A3Q1LYE2-1|A0A3Q1LYE2_BOVIN Computationally mapped isoform of Coatomer subunit zeta OS=Bos taurus OX=9913 GN=COPZ2 PE=3 SV=2 CANONICAL=A0A3Q1LRP8-1" }, "locus": { "chromosome": "19", "start_pos": 38453217, "end_pos": 38444034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070792.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070792.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060654.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060654.2" } ] } }, { "isoform_ac": "A0AAA9TP39-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP39/entry", "sequence": { "sequence": "MQRPEAWPRPHPGEGAAAAPTGGPAPPARAGEPAGLRLQEPSLYTIKAVFILDNDGHRLLAKYYDDTFPSMKEQMAFEKNVFNKTSRTDSEIAFFGGMTIVYKSSIDLFLYVVGSSYENELMLMSVLTCLFESLNHVLRKNVEKRWLLENMDGAFLVVDEIVDGGVILESDPQQVIQKVNFRADDSGLTEHSVAQNLPLFPFLRGVQKSLRVSITFGPGSLVSPDPEPTADASSRPALAPPLGAHRRGEPGPATLSTIL", "length": 259, "header": "tr|A0AAA9TP39-1|A0A3Q1LRP8_BOVIN Computationally mapped isoform of Coatomer subunit zeta OS=Bos taurus OX=9913 GN=COPZ2 PE=3 SV=1 CANONICAL=A0A3Q1LRP8-1" }, "locus": { "chromosome": "19", "start_pos": 38454351, "end_pos": 38444034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131791.2", "url": "https://www.ensembl.org/id/ENSBTAT00000131791.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100141.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100141.1" } ] } }, { "isoform_ac": "F1MXE6-1", "url": "https://www.uniprot.org/uniprotkb/F1MXE6/entry", "sequence": { "sequence": "MPGALGFEGPRGARGRRARGRRAGLQEPSLYTIKAVFILDNDGHRLLAKYYDDTFPSMKEQMAFEKNVFNKTSRTDSEIAFFGGMTIVYKSSIDLFLYVVGSSYENELMLMSVLTCLFESLNHVLRKNVEKRWLLENMDGAFLVVDEIVDGGVILESDPQQVIQKVNFRADDSGLTEHSVAQVLQSAKEQIKWSLLK", "length": 197, "header": "tr|F1MXE6-1|F1MXE6_BOVIN Computationally mapped isoform of Coatomer subunit zeta OS=Bos taurus OX=9913 GN=COPZ2 PE=3 SV=3 CANONICAL=A0A3Q1LRP8-1" }, "locus": { "chromosome": "19", "start_pos": 38453217, "end_pos": 38443764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056479.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056479.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051299.3", "url": "https://www.ensembl.org/id/ENSBTAP00000051299.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-BTA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde 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"MRFCGVGGLAESSFRERGRTQRPATQDWVEGQRRGGRARGGAALSVQAASGMQRPEAWPRPHPGEGASAAQAGGAAPPTRATEQRFQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFLAGMTIVYKSSIDIFLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRTDDSGLTEQSVAQVLQSAKEQIKWSLLK", "length": 258 }, "evidence": [ { "id": "A0A3Q1LRP8", "url": "https://omabrowser.org/oma/group/A0A3Q1LRP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54HD4-1", "protein_name": "Probable coatomer subunit zeta-A", "gene_name": "copZa", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSFLYTVTSFFILDSSKGERVIAKYYNNDFDTLQKQKAFEKKVFDKTSKVNFGGEITLLDNYLVVYKSFSNIIIYMVGDQNQNEIALLYVLNSFIDTLQNLFENSQINKKLILDGINYTLLTLDEIIDGGIIMESDSAVIADRVGIKAPDNDDLDESINKAVTSVKEQLFNFLK", "length": 175 }, "evidence": [ { "id": "A0A3Q1LRP8", "url": "https://omabrowser.org/oma/group/A0A3Q1LRP8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q84LG4-1", "protein_name": "Coatomer subunit zeta-2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSPDSCPLVKNILLLDSEGKRVAVKYYSDDWPTNAAKLSFEKYVFSKTSKTNARTEAEITLLDSNIIVYKFAQDLHFFVTGGENENELILASVLQGFFDAVALLLRSNVEKMEALENLDLIFLCLDEMVDQGVVLETDPNVIAGKVAMQSTEASGSLSEQTLTQALATAREHLARSLLT", "length": 179 }, "evidence": [ { "id": "A0A3Q1LRP8", "url": "https://omabrowser.org/oma/group/A0A3Q1LRP8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JHH9-1", "protein_name": "Coatomer subunit zeta-2", "gene_name": "Copz2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRPEAWPRPHPGEGASAAQAGGAAPPTRATEQREPSLYTIKAVFILDNDGRRLLAKYYDDTFPSVKEQMVFEKNVFNKTSRTESEIAFLGGMTIVYKSSIDIFLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDETVDGGVILESDPQQVIQKVNFRTDDSGLTEQSVAQVLQSAKEQIKWSLLK", "length": 205 }, "evidence": [ { "id": 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"binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9#function" }, { "database": "UniProtKB", "id": "ARBA00025297", "url": "https://www.uniprot.org/uniprotkb/ARBA00025297#function" }, { "database": "UniProtKB", "id": "A0ABI0NLT2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLT2#function" }, { "database": "UniProtKB", "id": "A0ABI0NYG3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYG3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SHANK2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9", "locus": { "chromosome": "29", "start_pos": 47560090, "end_pos": 47777015, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003171", "url": "https://www.ensembl.org/id/ENSBTAG00000003171" } ] } } ], "crossref": [ { "id": "A0A3Q1LRW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LRW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003171", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003171", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06746", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06746", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LRW9", "url": "https://www.orthodb.org/?gene=A0A3Q1LRW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NJZ2", "url": "https://www.orthodb.org/?gene=A0A3Q1NJZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NKF7", "url": "https://www.orthodb.org/?gene=A0A3Q1NKF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BKK6", "url": "https://www.orthodb.org/?gene=E1BKK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24135", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24135", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24135:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24135:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MME7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MME7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MME7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MME7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NKF7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NKF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLT2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLT2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYG3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKK6", "url": "https://www.uniprot.org/uniprotkb/E1BKK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKK6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRSPTSSEDEMAQSYSDSSEESDSDSSKEETIYDTIRATAQKPGGARAEEGQAHTLVLRIVIEDLQQTKCIRFNPDATVWVAKQRILCSLNQSLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPVGKGIPSLEFRYKKRVYRQTNLDEKQLAKLHTKTNLKKCMDHIQHRSVEKIVKMLDRGLDPNFHDLETGETPLTLAAQLDDPEEIIKALRNGGAHLDFRAKDGMTALHKAARTRNLLALKTLLELGASPDYKDSYGLTPLYHTAVVGGDPCCCELLLHEHAAVSCKDENGWHEIHQACRYGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQDSCARVLLFRGGDKELKNYNSQTPFQVAIIAGNFELAEYIKNHKETDVVPLVPTRRTVPAAPPLSHRPAGGWAQSCILEEPSGLFPPAPGLHRTCSGEQAHWTSSVPFREAPAYSNRRRRPPSTLAAPRLLLRSNSDNNLHAGAPDWAVCAATSRLSLSPQLLQQTPGKADGAAKTLGSYTPGPRSRSPSLNRLGGAGEDAKRPQQPWHVGPAFPPGANKDVLSAFEYPGPRRKLYSAVPGRLFVVVKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVHCKPRDSQAETRADRSKKLFRHYTVGSYDSFDASSDCVIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVTMIRQGGNHLVLKVVTVTRSLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELDKPEEIIPASKPSRAAESVALESRVATIRQRPTSRCFPSVADMNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTAYNCPKSPTPRVYGTIKPAFNQNPATKVSPAARSDTVATIVREKGLYHRREVDRYSLDSEDLYSRGTGPQANFRGKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSVETDPQASEQPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRARPSKFPEEGGFGEEDGAEPLSSPAPQEPENHFVGAGEAGAQGEAGRLPNAPGQAKVPEGSPAATPRSINIASPENYVHPLTGRLLDPSSPLALALSARDRALKESQQGPKGEAPKADLNKPLYIDTKMRPSGEAGFPPVGRQSGRGPLRRQETENKYETDPGKERRDDKKGVLVSIVDASQQKSAGLLMVHTVDAARPEDFLQEEDEKADPETQPDHLPSEAPEGAPETEGAFPTPAGPEPTAAAATAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRVASVPALSDLVKQKKNDTSQSPSLNSSQPTNSADSKKPAGLSNCLPASFLPPPESFDAVTDSGIEEVDSRGSSDHHLETTSTISTVSSISTLSSEGGENADTCTVYADGQAFMVDKPPVPPKPKMKPIIHKGNTLYHDALLEEDVDSFVVPPPAPPPPPGGAQPGPTKVIQPRTSRLWGDVSEVKSPILSGPKANVISELNSILQQMNREKSAKPGEGLDPTPGTKPAGLAPRGPEVISTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRNSGPRRAPSPVVSPTELNKEVLPAPLPAATAAPSPTLSDVFSLPSQPPPGDLFGLNPVGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR", "length": 1887, "header": "tr|A0A3Q1LRW9-1|A0A3Q1LRW9_BOVIN Isoform 1 of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=3 CANONICAL=A0A3Q1LRW9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9/entry", "sequence": { "sequence": "MPRSPTSSEDEMAQSYSDSSEESDSDSSKEETIYDTIRATAQKPGGARAEEGQAHTLVLRIVIEDLQQTKCIRFNPDATVWVAKQRILCSLNQSLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPVGKGIPSLEFRYKKRVYRQTNLDEKQLAKLHTKTNLKKCMDHIQHRSVEKIVKMLDRGLDPNFHDLETGETPLTLAAQLDDPEEIIKALRNGGAHLDFRAKDGMTALHKAARTRNLLALKTLLELGASPDYKDSYGLTPLYHTAVVGGDPCCCELLLHEHAAVSCKDENGWHEIHQACRYGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQDSCARVLLFRGGDKELKNYNSQTPFQVAIIAGNFELAEYIKNHKETDVVPLVPTRRTVPAAPPLSHRPAGGWAQSCILEEPSGLFPPAPGLHRTCSGEQAHWTSSVPFREAPAYSNRRRRPPSTLAAPRLLLRSNSDNNLHAGAPDWAVCAATSRLSLSPQLLQQTPGKADGAAKTLGSYTPGPRSRSPSLNRLGGAGEDAKRPQQPWHVGPAFPPGANKDVLSAFEYPGPRRKLYSAVPGRLFVVVKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVHCKPRDSQAETRADRSKKLFRHYTVGSYDSFDASSDCVIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVTMIRQGGNHLVLKVVTVTRSLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELDKPEEIIPASKPSRAAESVALESRVATIRQRPTSRCFPSVADMNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTAYNCPKSPTPRVYGTIKPAFNQNPATKVSPAARSDTVATIVREKGLYHRREVDRYSLDSEDLYSRGTGPQANFRGKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSVETDPQASEQPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRARPSKFPEEGGFGEEDGAEPLSSPAPQEPENHFVGAGEAGAQGEAGRLPNAPGQAKVPEGSPAATPRSINIASPENYVHPLTGRLLDPSSPLALALSARDRALKESQQGPKGEAPKADLNKPLYIDTKMRPSGEAGFPPVGRQSGRGPLRRQETENKYETDPGKERRDDKKGVLVSIVDASQQKSAGLLMVHTVDAARPEDFLQEEDEKADPETQPDHLPSEAPEGAPETEGAFPTPAGPEPTAAAATAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRVASVPALSDLVKQKKNDTSQSPSLNSSQPTNSADSKKPAGLSNCLPASFLPPPESFDAVTDSGIEEVDSRGSSDHHLETTSTISTVSSISTLSSEGGENADTCTVYADGQAFMVDKPPVPPKPKMKPIIHKGNTLYHDALLEEDVDSFVVPPPAPPPPPGGAQPGPTKVIQPRTSRLWGDVSEVKSPILSGPKANVISELNSILQQMNREKSAKPGEGLDPTPGTKPAGLAPRGPEVISTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRNSGPRRAPSPVVSPTELNKEVLPAPLPAATAAPSPTLSDVFSLPSQPPPGDLFGLNPVGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR", "length": 1887, "header": "tr|A0A3Q1LRW9-1|A0A3Q1LRW9_BOVIN Isoform 1 of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=3 CANONICAL=A0A3Q1LRW9-1" }, "locus": { "chromosome": "29", "start_pos": 48028011, "end_pos": 47561094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068330.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068330.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057817.3", "url": "https://www.ensembl.org/id/ENSBTAP00000057817.3" } ] } }, { "isoform_ac": "A0A3Q1MME7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MME7/entry", "sequence": { "sequence": "MMNVPGGASAAVMLTGYNNGRCPRNSLYSDCVIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVTMIRQGGNHLVLKVVTVTRSLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELVDKASVRKKKDKPEEIIPASKPSRAAESVALESRVATIRQRPTSRCFPSVADMNSVYERQGIAVMTPTVPGSPKGPFLGLPREAPRS", "length": 257, "header": "tr|A0A3Q1MME7-1|A0A3Q1LRW9_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=2 CANONICAL=A0A3Q1LRW9-1" }, "locus": { "chromosome": "29", "start_pos": 47720034, "end_pos": 47561648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087490.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087490.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072966.3", "url": "https://www.ensembl.org/id/ENSBTAP00000072966.3" } ] } }, { "isoform_ac": "A0A3Q1NJZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJZ2/entry", "sequence": { "sequence": "MMNVPGGASAAVMLTGYNNGRCPRNSLYSDCVIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVTMIRQGGNHLVLKVVTVTRSLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELVDKDKPEEIIPASKPSRAAESVALESRVATIRQRPTSRCFPSVADMNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTAYNCPKSPTPRVYGTIKPAFNQNPATKVSPAARSDTVATIVREKGLYHRREVDRYSLDSEDLYSRGTGPQANFRGKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSVETDPQASEQPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRARPSKFPEEGGFGEEDGAEPLSSPAPQEPENHFVGAGEAGAQGEAGRLPNAPGQAKVPEGSPAATPRSINIASPENYVHPLTGRLLDPSSPLALALSARDRALKESQQGPKGEAPKADLNKPLYIDTKMRPSGEAGFPPVGRQSGRGPLRRQETENKYETDPGKERRDDKKGVLVSIVDASQQKSAGLLMVHTVDAARPEDFLQEEDEKADPETQPDHLPSEAPEGAPETEGAFPTPAGPEPTAAAATAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRVASVPALSDLVKQKKNDTSQSPSLNSSQPTNSADSKKPAGLSNCLPASFLPPPESFDAVTDSGIEEVDSRGSSDHHLETTSTISTVSSISTLSSEGGENADTCTVYADGQAFMVDKPPVPPKPKMKPIIHKGNTLYHDALLEEDVDSFVVPPPAPPPPPGGAQPGPTKVIQPRTSRLWGDVSEVKSPILSGPKANVISELNSILQQMNREKSAKPGEGLDPTPGTKPAGLAPRGPEVISTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRNSGPRRAPSPVVSPTELNKEVLPAPLPAATAAPSPTLSDVFSLPSQPPPGDLFGLNPVGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR", "length": 1252, "header": "tr|A0A3Q1NJZ2-1|A0A3Q1LRW9_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=2 CANONICAL=A0A3Q1LRW9-1" }, "locus": { "chromosome": "29", "start_pos": 47720034, "end_pos": 47561094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084911.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084911.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072552.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072552.2" } ] } }, { "isoform_ac": "A0A3Q1NKF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKF7/entry", "sequence": { "sequence": "MVTPRLETMAENSRFKKKVHFGETRADRSKKLFRHYTVGSYDSFDASSDCVIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVTMIRQGGNHLVLKVVTVTRSLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELVDKASVRKKKDKPEEIIPASKPSRAAESVALESRVATIRQRPTSRCFPSVADMNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTAYNCPKSPTPRVYGTIKPAFNQNPATKVSPAARSDTVATIVREKGLYHRREVDRYSLDSEDLYSRGTGPQANFRGKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSVETDPQASEQPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRARPSKFPEEGGFGEEDGAEPLSSPAPQEPENHFVGAGEAGAQGEAGRLPNAPGQAKVPEGSPAATPRSINIASPENYVHPLTGRLLDPSSPLALALSARDRALKESQQGPKGEAPKADLNKPLYIDTKMRPSGEAGFPPVGRQSGRGPLRRQETENKYETDPGKERRDDKKGVLVSIVDASQQKSAGLLMVHTVDAARPEDFLQEEDEKADPETQPDHLPSEAPEGAPETEGAFPTPAGPEPTAAAATAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRVASVPALSDLVKQKKNDTSQSPSLNSSQPTNSADSKKPAGLSNCLPASFLPPPESFDAVTDSGIEEVDSRGSSDHHLETTSTISTVSSISTLSSEGGENADTCTVYADGQAFMVDKPPVPPKPKMKPIIHKGNTLYHDALLEEDVDSFVVPPPAPPPPPGGAQPGPTKVIQPRTSRLWGDVSEVKSPILSGPKANVISELNSILQQMNREKSAKPGEGLDPTPGTKPAGLAPRGPEVISTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRNSGPRRAPSPVVSPTELNKEVLPAPLPAATAAPSPTLSDVFSLPSQPPPGDLFGLNPVGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR", "length": 1278, "header": "tr|A0A3Q1NKF7-1|A0A3Q1LRW9_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=2 CANONICAL=A0A3Q1LRW9-1" }, "locus": { "chromosome": "29", "start_pos": 47776716, "end_pos": 47561094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086380.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086380.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072812.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072812.2" } ] } }, { "isoform_ac": "A0ABI0NLT2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLT2/entry", "sequence": { "sequence": 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"length": 1803, "header": "tr|A0ABI0NLT2-1|A0ABI0NLT2_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=1 CANONICAL=A0A3Q1LRW9-1" }, "locus": { "chromosome": "29", "start_pos": 48028011, "end_pos": 47561094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139514.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139514.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106240.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106240.1" } ] } }, { "isoform_ac": "A0ABI0NYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYG3/entry", "sequence": { "sequence": "MPRSPTSSEDEMAQSYSDSSEESDSDSSKEETIYDTIRATAQKPGGARAEEGQAHTLVLRIVIEDLQQTKCIRFNPDATVWVAKQRILCSLNQSLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPVGKGIPSLEFRYKKRVYRQTNLDEKQLAKLHTKTNLKKCMDHIQHRSVEKIVKMLDRGLDPNFHDLETGETPLTLAAQLDDPEEIIKALRNGGAHLDFRAKDGMTALHKAARTRNLLALKTLLELGASPDYKDSYGLTPLYHTAVVGGDPCCCELLLHEHAAVSCKDENGWHEIHQACRYGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQDSCARVLLFRGGDKELKNYNSQTPFQVAIIAGNFELAEYIKNHKETDVVPFREAPAYSNRRRRPPSTLAAPRLLLRSNSDNNLHAGAPDWAVCAATSRLSLSPQLLQQTPGKADGAAKTLGSYTPGPRSRSPSLNRLGGAGEDAKRPQQPWHVGPAFPPGANKDVLSAFEYPGPRRKLYSAVPGRLFVVVKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVHCKPRDSQAETRADRSKKLFRHYTVGSYDSFDASSDCVIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVTMIRQGGNHLVLKVVTVTRSLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELVDKASVRKKKDKPEEIIPASKPSRAAESVALESRVATIRQRPTSRCFPSVADMNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTAYNCPKSPTPRVYGTIKPAFNQNPATKVSPAARSDTVATIVREKGLYHRREVDRYSLDSEDLYSRGTGPQANFRGKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSVETDPQASEQPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRARPSKFPEEGGFGEEDGAEPLSSPAPQEPENHFVGAGEAGAQGEAGRLPNAPGQAKVPEGSPAATPRSINIASPENYVHPLTGRLLDPSSPLALALSARDRALKESQQGPKGEAPKADLNKPLYIDTKMRPSGEAGFPPVGRQSGRGPLRRQETENKYETDPGKERRDDKKGVLVSIVDASQQKSAGLLMVHTVDAARPEDFLQEEDEKADPETQPDHLPSEAPEGAPETEGAFPTPAGPEPTAAAATAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRVASVPALSDLVKQKKNDTSQSPSLNSSQPTNSADSKKPAGLSNCLPASFLPPPESFDAVTDSGIEEVDSRGSSDHHLETTSTISTVSSISTLSSEGGENADTCTVYADGQAFMVDKPPVPPKPKMKPIIHKGNTLYHDALLEEDVDSFVVPPPAPPPPPGGAQPGPTKVIQPRTSRLWGDVSEVKSPILSGPKANVISELNSILQQMNREKSAKPGEGLDPTPGTKPAGLAPRGPEVISTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRNSGPRRAPSPVVSPTELNKEVLPAPLPAATAAPSPTLSDVFSLPSQPPPGDLFGLNPVGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR", "length": 1847, "header": "tr|A0ABI0NYG3-1|A0ABI0NYG3_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=1 CANONICAL=A0A3Q1LRW9-1" }, "locus": { "chromosome": "29", "start_pos": 48028011, "end_pos": 47561094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107287.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107287.1" } ] } }, { "isoform_ac": "E1BKK6-1", "url": "https://www.uniprot.org/uniprotkb/E1BKK6/entry", "sequence": { "sequence": "MKSLLNAFTKKEVPFREAPAYSNRRRRPPSTLAAPRLLLRSNSDNNLHAGAPDWAVCAATSRLSLSPQLLQQTPGKADGAAKTLGSYTPGPRSRSPSLNRLGGAGEDAKRPQQPWHVGPAFPPGANKDVLSAFEYPGPRRKLYSAVPGRLFVVVKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVHCKPRDSQAETRADRSKKLFRHYTVGSYDSFDASSDCVIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVTMIRQGGNHLVLKVVTVTRSLDPDDTARKKAPPPPKRAPTTALTLRSKSMTSELEELVDKASVRKKKDKPEEIIPASKPSRAAESVALESRVATIRQRPTSRCFPSVADMNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTAYNCPKSPTPRVYGTIKPAFNQNPATKVSPAARSDTVATIVREKGLYHRREVDRYSLDSEDLYSRGTGPQANFRGKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSVETDPQASEQPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRARPSKFPEEGGFGEEDGAEPLSSPAPQEPENHFVGAGEAGAQGEAGRLPNAPGQAKVPEGSPAATPRSINIASPENYVHPLTGRLLDPSSPLALALSARDRALKESQQGPKGEAPKADLNKPLYIDTKMRPSGEAGFPPVGRQSGRGPLRRQETENKYETDPGKERRDDKKGVLVSIVDASQQKSAGLLMVHTVDAARPEDFLQEEDEKADPETQPDHLPSEAPEGAPETEGAFPTPAGPEPTAAAATAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFANSFDIPDDRVASVPALSDLVKQKKNDTSQSPSLNSSQPTNSADSKKPAGLSNCLPASFLPPPESFDAVTDSGIEEVDSRGSSDHHLETTSTISTVSSISTLSSEGGENADTCTVYADGQAFMVDKPPVPPKPKMKPIIHKGNTLYHDALLEEDVDSFVVPPPAPPPPPGGAQPGPTKVIQPRTSRLWGDVSEVKSPILSGPKANVISELNSILQQMNREKSAKPGEGLDPTPGTKPAGLAPRGPEVISTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRNSGPRRAPSPVVSPTELNKEVLPAPLPAATAAPSPTLSDVFSLPSQPPPGDLFGLNPVGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR", "length": 1468, "header": "tr|E1BKK6-1|A0A3Q1LRW9_BOVIN Computationally mapped isoform of SH3 and multiple ankyrin repeat domains 2 OS=Bos taurus OX=9913 GN=SHANK2 PE=4 SV=4 CANONICAL=A0A3Q1LRW9-1" }, "locus": { "chromosome": "29", "start_pos": 47859162, "end_pos": 47561094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044310.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044310.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041818.5", "url": "https://www.ensembl.org/id/ENSBTAP00000041818.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1395, "start_aa": "Thr", "end_pos": 1395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1395", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1402, "start_aa": "Thr", "end_pos": 1402, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1402", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1687, "start_aa": "Thr", "end_pos": 1687, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1687", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 712, "start_aa": "Thr", "end_pos": 712, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr712", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" }, { "name": "adult behavior", "id": "GO:0030534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030534", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" }, { "name": "vocalization behavior", "id": "GO:0071625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071625", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRW9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1481, "end_pos": 1483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1490, "end_pos": 1492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 682, "end_pos": 776, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 1824, "end_pos": 1887, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LRW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRW9" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 582, "end_pos": 641, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 712, 1395, 1402, 1687 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1481, "end_pos": 1483 }, { "start_pos": 1490, "end_pos": 1492 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LRF8-1", "uniprot_ac": "A0A3Q1LRF8", "uniprot_id": "A0A3Q1LRF8_BOVIN", "mass": { "chemical_mass": 91819.0, "monoisotopic_mass": 91819.0 }, "refseq": { "ac": "XP_024832532", "name": "espin isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832532" }, "gene_names": [ { "name": "ESPN", "type": "recommended", "evidence": [ { "id": "A0A3Q1LRF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8" } ] }, { "name": "ESPN", "type": "synonym", "evidence": [ { "id": "XP_024832532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832532" } ] } ], "protein_names": [ { "name": "Espin", "type": "recommended", "evidence": [ { "id": "A0A3Q1LRF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8/entry#names_and_taxonomy" } ] }, { "name": "Ectoplasmic specialization protein", "type": "synonym", "evidence": [ { "id": "A0A3Q1LRF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8/entry#names_and_taxonomy" } ] }, { "name": "espin isoform X4", "type": "synonym", "evidence": [ { "id": "XP_024832532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832532" } ] } ], "function": [ { "annotation": "Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells. Required for the assembly and stabilization of the stereociliary parallel actin bundles. Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia. Involved in the elongation of actin in stereocilia. In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRF8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8#function" }, { "database": "UniProtKB", "id": "ARBA00057682", "url": "https://www.uniprot.org/uniprotkb/ARBA00057682#function" }, { "database": "UniProtKB", "id": "A0AAA9S2J9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2J9#function" }, { "database": "UniProtKB", "id": "A0AAA9S3H0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3H0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRF8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ESPN", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8", "locus": { "chromosome": "16", "start_pos": 46909357, "end_pos": 46943795, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006515", "url": "https://www.ensembl.org/id/ENSBTAG00000006515" } ] } } ], "crossref": [ { "id": "A0A3Q1LRF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LRF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006515", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006515", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "104976499", "url": "https://www.ncbi.nlm.nih.gov/gene/104976499", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:104976499", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:104976499", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24153:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24153:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024832532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRF8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2J9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2J9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2J9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2J9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3H0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHC8", "url": "https://www.uniprot.org/uniprotkb/E1BHC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHC8-1", "url": "https://www.uniprot.org/uniprotkb/E1BHC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALEQAMQAARQGDLDVLRSLHAARLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAGLPAAARARNGATPAHDAAATGHLACLQLLLSQGGCGVHDRDNSGATVLHLAARFGHPEVVNWLLRHGGGNPTMATDTGALPVHYAAAKGDFPSLRLLVRSHPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECDADPHLSAHDGMTPLHAAAQMGHISVIVWLVSCTDVSLSEKDKDGATAMHFAASRGHAKVLSWLLLHGGEIVADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLADYNGHSHCTRYLRTVENLSVEHRVLSRDPSTDLETKQPDSGMSSPNTTMSVQRPNFDLSSPTSTLSNYDSCSSGHSSVKGQRSVRGVPSPRAADIQSYMDMLSPEPDLPRGKMEKTKAPPPPPGFPPPPPPPGTQLPPPPPGFPAPKPPEGLQAADIYLQTKNKLRHVETEAFKKEPSSRDGRNGLRRQDSGRKPRAFSKQPSTGDYYRQLGRHPGEPLVARPGMAHSEEVRARQPAPAGRPGPGWAARISLAGPSAPPQAVLLPGNHVHNGCGADPKASRELPPPPPPPPLPEALSSPPPAPPLPFEGSGPGCGQRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESPLPPVSPAPSRARSPTPPAVGSQPLLNGSVAPAPPATPAPGVQLDVEALIPTYDEQGRPIPEWKRQVMVRKLQLKMQEEEEQRRKEEQEEAWLASMPAWRRDILRKKLEDEREQKRKQEERQKQEEMQREKEQSEKLRTLGYDESKLAPWQRQIILKKGDIAKY", "length": 852, "header": "tr|A0A3Q1LRF8-1|A0A3Q1LRF8_BOVIN Isoform 1 of Espin OS=Bos taurus OX=9913 GN=ESPN PE=4 SV=2 CANONICAL=A0A3Q1LRF8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRF8/entry", "sequence": { "sequence": "MALEQAMQAARQGDLDVLRSLHAARLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAGLPAAARARNGATPAHDAAATGHLACLQLLLSQGGCGVHDRDNSGATVLHLAARFGHPEVVNWLLRHGGGNPTMATDTGALPVHYAAAKGDFPSLRLLVRSHPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECDADPHLSAHDGMTPLHAAAQMGHISVIVWLVSCTDVSLSEKDKDGATAMHFAASRGHAKVLSWLLLHGGEIVADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLADYNGHSHCTRYLRTVENLSVEHRVLSRDPSTDLETKQPDSGMSSPNTTMSVQRPNFDLSSPTSTLSNYDSCSSGHSSVKGQRSVRGVPSPRAADIQSYMDMLSPEPDLPRGKMEKTKAPPPPPGFPPPPPPPGTQLPPPPPGFPAPKPPEGLQAADIYLQTKNKLRHVETEAFKKEPSSRDGRNGLRRQDSGRKPRAFSKQPSTGDYYRQLGRHPGEPLVARPGMAHSEEVRARQPAPAGRPGPGWAARISLAGPSAPPQAVLLPGNHVHNGCGADPKASRELPPPPPPPPLPEALSSPPPAPPLPFEGSGPGCGQRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESPLPPVSPAPSRARSPTPPAVGSQPLLNGSVAPAPPATPAPGVQLDVEALIPTYDEQGRPIPEWKRQVMVRKLQLKMQEEEEQRRKEEQEEAWLASMPAWRRDILRKKLEDEREQKRKQEERQKQEEMQREKEQSEKLRTLGYDESKLAPWQRQIILKKGDIAKY", "length": 852, "header": "tr|A0A3Q1LRF8-1|A0A3Q1LRF8_BOVIN Isoform 1 of Espin OS=Bos taurus OX=9913 GN=ESPN PE=4 SV=2 CANONICAL=A0A3Q1LRF8-1" }, "locus": { "chromosome": "16", "start_pos": 46943596, "end_pos": 46910361, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075923.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075923.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057626.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057626.2" } ] } }, { "isoform_ac": "A0AAA9S2J9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2J9/entry", "sequence": { "sequence": "MALEQAMQAARQGDLDVLRSLHAARLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAGLPAAARARNGATPAHDAAATGHLACLQLLLSQGGCGVHDRDNSGATVLHLAARFGHPEVVNWLLRHGGGNPTMATDTGALPVHYAAAKGDFPSLRLLVRSHPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECDADPHLSAHDGMTPLHAAAQMGHISVIVWLVSCTDVSLSEKDKDGATAMHFAASRGHAKVLSWLLLHGGEIVADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLADYNGHSHCTRYLRTVENLSVEHRVLSRDPSTDLETKQPDSGMSSPNTTMSVQRPNFDLSSPTSTLSNYDSCSSGHSSVKGQRSVRGVPSPRAADIQSYMDMLSPEPDLPRGKMEKTKAPPPPPGFPPPPPPPGTQLPPPPPGFPAPKPPEGLQAADIYLQTKNKLRHVETEAFKKEPSSRDGRNGLRRQDSGRKPRAFSKQPSTGDYYRQLGRHPGEPLVARPGMAHSEEAVLLPGNHVHNGCGADPKASRELPPPPPPPPLPEALSSPPPAPPLPFEGSGPGCGQRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESPLPPVSPAPSRARSPTPPAVGSQPLLNGSVAPAPPATPAPGVQLDVEALIPTYDEQGRPIPEWKRQVMVRKLQLKMQEEEEQRRKLTATSSCCYPREGWRYSREHNAILGPFGELMTEADILRIEQQIENLQVLHKAQKLEARLEQLELELEQLLPISAALSAPRFTVDPRRMHGRAASLPAWCSKISVLLKSMASLLAALGGRPAHPAELLAADTGQPLPPLIDAPWRPGPLCLGRSHSLSWCREAVAREILECGVSVRHLRTMYERRALGSEPPRGPRRKLSLPASAPDREPILEEDYAVASPSEPSAAVAATTNGLPAAGEYVGGLDAPVAPGRQAALPGPEQLARRPPSSTELRGVQDYIDMRKERIVYLFLEHWRKSTFRGPGHHAQVRLRRLLPRVVAAGAGADPGPEAAAVSWPPAGDGPDERLLRLLKQRQVVGKLLGHWRSLLRQVPARQPPGRALAHGLYWPEHFLPPLDGGAPRRYDSLTLDLFMLGYFQLLEMGLSREERKFRHLLCYEMFDRLGSHPWELIRLFHRVVIEEVEAGRRSWSDGFEDLRRQFFEDSPEAEPARGEETEKEQKEGTDKDERELMEEASTAQAGNWPEGQPEAPTPARLPPPSPPPAPPPTSVPPSSEDPLELVSEMGEFSNEDICRRSRRRPGWPACLPGGGTSCGRS", "length": 1336, "header": "tr|A0AAA9S2J9-1|A0A3Q1LRF8_BOVIN Computationally mapped isoform of Espin OS=Bos taurus OX=9913 GN=ESPN PE=4 SV=1 CANONICAL=A0A3Q1LRF8-1" }, "locus": { "chromosome": "16", "start_pos": 46943596, "end_pos": 46911769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103370.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103370.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079268.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079268.1" } ] } }, { "isoform_ac": "A0AAA9S3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3H0/entry", "sequence": { "sequence": "MALEQAMQAARQGDLDVLRSLHAARLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAGLPAAARARNGATPAHDAAATGHLACLQLLLSQGGCGVHDRDNSGATVLHLAARFGHPEVVNWLLRHGGGNPTMATDTGALPVHYAAAKGDFPSLRLLVRSHPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECDADPHLSAHDGMTPLHAAAQMGHISVIVWLVSCTDVSLSEKDKDGATAMHFAASRGHAKVLSWLLLHGGEIVADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLADYNGHSHCTRYLRTVENLSVEHRVLSRDPSTDLETKQPDSGMSSPNTTMSVQRPNFDLSSPTSTLSNYDSCSSGHSSVKGQRSVRGVPSPRAADIQSYMDMLSPEPDLPRGKMEKTKAPPPPPGFPPPPPPPGTQLPPPPPGFPAPKPPEGLQAADIYLQTKNKLRHVETEAFKKEPSSRDGRNGLRRQDSGRKPRAFSKQPSTGDYYRQLGRHPGEPLVARPGMAHSEEAVLLPGNHVHNGCGADPKASRELPPPPPPPPLPEALSSPPPAPPLPFEGSGPGCGQRRSSSSTGKVRVLRHRKSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESPLPPVSPAPSRARSPTPPAVGSQPLLNGSVAPAPPATPAPGVQLDVEALIPTYDEQGRPIPEWKRQVMVRKLQLKMQEEEEQRRKEEQEEAWLASMPAWRRDILRKKLEDEREQKRKQEERQKQEEMQREKEQSEKLRTLGYDESKLAPWQRQIILKKGDIAKY", "length": 831, "header": "tr|A0AAA9S3H0-1|A0A3Q1LRF8_BOVIN Computationally mapped isoform of Espin OS=Bos taurus OX=9913 GN=ESPN PE=4 SV=1 CANONICAL=A0A3Q1LRF8-1" }, "locus": { "chromosome": "16", "start_pos": 46943596, "end_pos": 46910361, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116231.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116231.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078322.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078322.1" } ] } }, { "isoform_ac": "E1BHC8-1", "url": "https://www.uniprot.org/uniprotkb/E1BHC8/entry", "sequence": { "sequence": "MALEQAMQAARQGDLDVLRSLHAARLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAGLPAAARARNGATPAHDAAATGHLACLQLLLSQGGCGVHDRDNSGATVLHLAARFGHPEVVNWLLRHGGGNPTMATDTGALPVHYAAAKGDFPSLRLLVRSHPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECDADPHLSAHDGMTPLHAAAQMGHISVIVWLVSCTDVSLSEKDKDGATAMHFAASRGHAKVLSWLLLHGGEIVADLWGGTPLHDAAENGELESVEHRVLSRDPSTDLETKQPDSGMSSPNTTMSVQRPNFDLSSPTSTLSNYDSCSSGHSSVKGQRSVRGVPSPRAADIQSYMDMLSPEPDLPRGKMEKTKAPPPPPGFPPPPPPPGTQLPPPPPGFPAPKPPEGLQAADIYLQTKNKLRHVETEAFKKEPSSRDGRNGLRRQDSGRKPRAFSKQPSTGDYYRQLGRHPGEPLVARPGMAHSEEAVLLPGNHVHNGCGADPKASRELPPPPPPPPLPEALSSPPPAPPLPFEGSGPGCGQRRSSSSTGKVRVLRHRKSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESPLPPVSPAPSRARSPTPPAVGSQPLLNGSVAPAPPATPAPGVQLDVEALIPTYDEQGRPIPEWKRQVMVRKLQLKMQEEEEQRRKEEQEEAWLASMPAWRRDILRKKLEDEREQKRKQEERQKQEEMQREKEQSEKLRTLGYDESKLAPWQRQIILKKGDIAKY", "length": 787, "header": "tr|E1BHC8-1|A0A3Q1LRF8_BOVIN Computationally mapped isoform of Espin OS=Bos taurus OX=9913 GN=ESPN PE=4 SV=4 CANONICAL=A0A3Q1LRF8-1" }, "locus": { "chromosome": "16", "start_pos": 46943596, "end_pos": 46910361, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045529.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045529.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042910.5", "url": "https://www.ensembl.org/id/ENSBTAP00000042910.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 704, "start_aa": "Thr", "end_pos": 704, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr704", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13771:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-198933", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LT76", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWY8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M546", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M546", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M546-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M546-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M563", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M563", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M563-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M563-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M932", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M932", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M932-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M932-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NKV8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NKV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6E1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6E1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B997", "url": "https://www.uniprot.org/uniprotkb/E1B997", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B997-1", "url": "https://www.uniprot.org/uniprotkb/E1B997-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALTSLLPTEPASRGPKDSFRPGCKGLKPGSEIRSSPGNSGCWKLDLSHPVYPSQHHPFADTGSPQPFPVSLRTPPKMSPFGGWGMLAAFLAMLCCRGSGEKAFEGPEHLMVGSGEFQMINCTASCTDPTNLILETALNKTLLESQAQWKLFQVYNISKDEELLCSFTCAGKQEMKVFNITVFYPPKQVLLTLSHTSVAVGTLFTIECRVPAVAPLEGLTVTLLRGTEILHNQTFEETAPFPHDAVVTHHTTAHREDGHHNFSCEAQMDLRSRGGGLVHRVSDPQRLEVKEPEPNYQMVIMAIVIVLLLLFVTFVFLCFVFSEKWRRGRTGHYPVQAAWNRLRRSHRAQPL", "length": 351, "header": "tr|A0A3Q1LWY8-1|A0A3Q1LWY8_BOVIN Isoform 1 of Intercellular adhesion molecule N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342121 PE=3 SV=2 CANONICAL=A0A3Q1LWY8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LT76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT76/entry", "sequence": { "sequence": "MALTSLLPTEPASRGPKDSFRPGCKGLKPGSEIRSSPGNSGCWKLDLSHPVYPSQHHPFADTGSPQPFPVSLRRPPKMSPFGGWGSLTAFLALLCCQGSGGKAFEGPEHLMVGSGEFQVINCTASCTDPKSLVLETHLNKTLLESQAQWKLFRVYNISKDEELLCSFTCAGKQETKVFNITVFYPPKQVLLTLSHTSVAVGTLFTIECMVPAVAPLEGLTVTLLRGTEILYNQTFVGTARFPQDAVVTHHTTAHREDGHHNFSCEAQMDLRSRGGGLVHRVSDPQRLEVKEPVPNNQMVTIITIVIMLLILFVTFVLLCRHRLRTSNT", "length": 328, "header": "tr|A0A3Q1LT76-1|A0A3Q1LT76_BOVIN Computationally mapped isoform of Intercellular adhesion molecule N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342121 PE=3 SV=3 CANONICAL=A0A3Q1LWY8-1" }, "locus": { "chromosome": "19", "start_pos": 48249727, "end_pos": 48220301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087092.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087092.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063642.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063642.3" } ] } }, { "isoform_ac": "A0A3Q1LWY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWY8/entry", "sequence": { "sequence": "MALTSLLPTEPASRGPKDSFRPGCKGLKPGSEIRSSPGNSGCWKLDLSHPVYPSQHHPFADTGSPQPFPVSLRTPPKMSPFGGWGMLAAFLAMLCCRGSGEKAFEGPEHLMVGSGEFQMINCTASCTDPTNLILETALNKTLLESQAQWKLFQVYNISKDEELLCSFTCAGKQEMKVFNITVFYPPKQVLLTLSHTSVAVGTLFTIECRVPAVAPLEGLTVTLLRGTEILHNQTFEETAPFPHDAVVTHHTTAHREDGHHNFSCEAQMDLRSRGGGLVHRVSDPQRLEVKEPEPNYQMVIMAIVIVLLLLFVTFVFLCFVFSEKWRRGRTGHYPVQAAWNRLRRSHRAQPL", "length": 351, "header": "tr|A0A3Q1LWY8-1|A0A3Q1LWY8_BOVIN Isoform 1 of Intercellular adhesion molecule N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342121 PE=3 SV=2 CANONICAL=A0A3Q1LWY8-1" }, "locus": { "chromosome": "19", "start_pos": 48249727, "end_pos": 48205016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078625.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078625.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059996.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059996.2" } ] } }, { "isoform_ac": "A0A3Q1M546-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M546/entry", "sequence": { "sequence": "MSPFGGWGMLAAFLAMLCCRGSNEKVFEGPEHLMVGFGEFQVINCTASCTDPKKLVLETHLNKTLLDSQAQWKLFQVYNISKDEELLCSFTCAGKQEMKVFNITVFYPPKQVLLTLSHTSVAVGTLFTIECRVPAVAPLEGLTVTLLRGTEILHNQTFEETAPFPHDAVVTHHTTAHREDGHHNFSCEAQMDLRSRGGGLVHRVSDPQRLEVKEPEPNYQMVIMAIVIVLLLLFVTFVFLCFVFSEKWRRGRTGHYPVQAAWNRLRRSHRAQPL", "length": 274, "header": "tr|A0A3Q1M546-1|A0A3Q1M546_BOVIN Computationally mapped isoform of Intercellular adhesion molecule N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342121 PE=3 SV=2 CANONICAL=A0A3Q1LWY8-1" }, "locus": { "chromosome": "19", "start_pos": 48224433, "end_pos": 48205016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073910.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073910.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064976.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064976.2" } ] } 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{ "database": "Ensembl Peptide", "id": "ENSBTAP00000073014.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073014.2" } ] } }, { "isoform_ac": "A0AAA9S6E1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E1/entry", "sequence": { "sequence": "MALTSLLPTEPASRGPKDSFRPGCKGLKPGSEIRSSPGNSGCWKLDLSHPVYPSQHHPFADTGSPQLFPVSLRTPPKMSPFGGWGMLAAFLAMLCCQGSGEKAFEGPEHLMTALNKTLLESQAQWKLFQVYNISKDEELLCSFTCAGKQEMKVFNITVFYPPKQVLLTLSHTSVAVGTLFTIECRVPAVAPLEGLTVTLLRGTEILHNQTFEETAPFPHDAVVTHHTTAHREDGHHNFSCEAQMDLRSRGGGLVHRVSDPQRLEVKEPEPNYQMVIMAIVIVLLLLFVTFVFLCFVFSEKWRRGRTGHYPVQAAWNRLRRSHRAQPL", "length": 327, "header": "tr|A0AAA9S6E1-1|A0A3Q1LWY8_BOVIN Computationally mapped isoform of Intercellular adhesion molecule N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC132342121 PE=3 SV=2 CANONICAL=A0A3Q1LWY8-1" }, "locus": { "chromosome": "19", "start_pos": 48249727, "end_pos": 48205016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126571.2", "url": 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"https://www.orthodb.org/?gene=F1MLU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18864", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18864", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18864:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18864:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5625970", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5625970", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005211892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVJ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2E2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFW6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNV3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRI4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVA3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SW07", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SW07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZY7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZY7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MLU7", "url": "https://www.uniprot.org/uniprotkb/F1MLU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MLU7-1", "url": "https://www.uniprot.org/uniprotkb/F1MLU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1329, "header": "tr|A0A3Q1LVS2-1|A0A3Q1LVS2_BOVIN Isoform 1 of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ8/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLD", "length": 1306, "header": "tr|A0A3Q1LVJ8-1|A0A3Q1LVJ8_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=2 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68112025, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066733.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066733.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061432.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061432.2" } ] } }, { "isoform_ac": "A0A3Q1LVS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1329, "header": "tr|A0A3Q1LVS2-1|A0A3Q1LVS2_BOVIN Isoform 1 of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069650.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069650.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064758.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064758.1" } ] } }, { "isoform_ac": "A0A3Q1M2E2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2E2/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1304, "header": "tr|A0A3Q1M2E2-1|A0A3Q1M2E2_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=3 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084880.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084880.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063945.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063945.3" } ] } }, { "isoform_ac": "A0AAA9SFW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFW6/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1357, "header": "tr|A0AAA9SFW6-1|A0A3Q1LVS2_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120578.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120578.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082769.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082769.1" } ] } }, { "isoform_ac": "A0AAA9SNV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNV3/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1306, "header": "tr|A0AAA9SNV3-1|A0A3Q1LVS2_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124267.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124267.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085576.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085576.1" } ] } }, { "isoform_ac": "A0AAA9SRI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRI4/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKERQQHVEAVELEAKEVLKKLFPKVSVPSNLDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1302, "header": "tr|A0AAA9SRI4-1|A0A3Q1LVS2_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105189.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105189.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085587.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085587.1" } ] } }, { "isoform_ac": "A0AAA9SVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVA3/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1270, "header": "tr|A0AAA9SVA3-1|A0A3Q1LVS2_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090599.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090599.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090398.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090398.1" } ] } }, { "isoform_ac": "A0AAA9SW07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW07/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1299, "header": "tr|A0AAA9SW07-1|A0A3Q1LVS2_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103204.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103204.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087391.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087391.1" } ] } }, { "isoform_ac": "A0AAA9SZY7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZY7/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKLLQDKVNKTSKERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1333, "header": "tr|A0AAA9SZY7-1|A0A3Q1LVS2_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=1 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108866.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108866.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089693.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089693.1" } ] } }, { "isoform_ac": "F1MLU7-1", "url": "https://www.uniprot.org/uniprotkb/F1MLU7/entry", "sequence": { "sequence": "MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPVPLNVVESPTSVRERKKKEKKHKPVLEEQVTKESDVSKIPCKKVEPVPVTKQPTPPSEAPASKKKPGQKKSKNGSDDQDKKVESLAAPSKKQESLPLHQETKQESGSGKKKVSSKKQKTENVLVDEPLIHATTYIPLMDNADSNPVVDKREVIDLIKPDQVEVIQKTGAKKLKIETDKENAEVKFKDFLLSLKTMMFSEEEALCVVDLLKEKSGVIQDALKKYNKGELTALVHQLQEKDKLVTALKEDAASMKDRCKQLTQEMMAEKERSSVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVSELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASALAEELHKVIAEKDKQIKQTEDSLANEHDHLASKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDKIRLLEEQLQCEISNKMEEFKILSDQNKALQLEVQKLQTLVSEQPNKDVLEQMERCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLAKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQVQELQNLLKGKEEQMNNMKTVLEEKEKDLHNRGRRLQDLQEENESLKTHVQEFAQHKFQEACSASQFEELQIVLKEKENEMKRLETMLKERESDLSSKTKLLQEVQDENKLFKSQIEELKQQNYQQASSFPPHEELLKVISEREKEITDLKNELDSLKDAVEHQRKKNNERQQHVEAVELEAKEVLKKLFPKVSVPSNLSYSEWLHGFEKKAKECVAAASGSEEVKDLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSLEQELDRLRRENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKKQLNETHAKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSQETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1328, "header": "tr|F1MLU7-1|F1MLU7_BOVIN Computationally mapped isoform of Kinectin 1 OS=Bos taurus OX=9913 GN=KTN1 PE=1 SV=5 CANONICAL=A0A3Q1LVS2-1" }, "locus": { "chromosome": "10", "start_pos": 68118588, "end_pos": 68035868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043690.6", "url": "https://www.ensembl.org/id/ENSBTAT00000043690.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041243.6", "url": "https://www.ensembl.org/id/ENSBTAP00000041243.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-5625970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5625970", "resource": "Reactome", "description": "RHO GTPases activate KTN1" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-BTA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-BTA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A4W2-1", "protein_name": "Kinectin 1", "gene_name": "Ktn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELHESTYFVVLIPSVVITVIFLFFWLFMKETLYDDVLAKQKREQKLISTKADKKKAEKKKNKKKEIQNGTLHESDSEHVPQDFKLSDASPVEDEQFVPAPLSVAETSSSVRERKKKEKKQKPSLEEHIIKESDASKIPGKKVEPVLVTEQPAPPPEAAALKKKAGQKKSKNGSDELDKKVEMVMAPSQKQDGSLFHQETKQEGGPGKKKGLSKKQKTENVAVLVDEPLTHATASVPSVDNADSSLMTDKRGVTDMIKPDQVEGIQKSGTKKLKIDTDKENAEVKFKNFLLSLKTMMFSEDEALCVVDLLKEKSGVIKEALKKSNKGELSGLLHQLQEKERLLTATKEDAAATKERCKQLTQEMMTEKERSSVVMARMKERIGTLEKEHNIFQNKMHVSYQETQQMQMKFEQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDCGRLVSELNEKTGKLQQEGVQKKNAEQAAAQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRASQEESMQIQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQLKQTEDSLASEQDHLASKEQELKDVQNVNFLLKAEVQKLQALAKEQAAAAHEVEKMQKSVHVKDDKIRLLEEQLQREVASRVEELKILNDQNKALQLEVQKLQAVVSEQPNKDVVEQMKKCIQEKDEKLRTVEELLETGLIQVATREEELNAIRTENSSLTKEVQELKAKQMDQVPFVSLIEDLKKVIHEKDGQIKSVEELLEVELLKVANKEKTVQALKQEIEILKEEIGNAQLEKAHQLSVTSQVQELQNLLRGKEEQVDSMKAALEDLTGREKCTQVCSTPRFEELENVLKEKDNEIKRIEAILKDTKSDLSKKAELLKEVQDENKLFKSQVEQLNHQNHQQASFPSQEELQTVISEKEKEITDLCNELESLKNAVEHQRKKNNDLREKNWEAMEALASTEKILQDRVNKTSKERQQQVEAVELESKDLLKRLFPAVSVPSHSNYSEWLRSFEKKAKACMAGPSDTEAVKVLEHRLKEANEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEESKWKVKAEESRRTIQQMQSSFTASEQELERLRHENKAMENLRREREHLEIELEKAEVERSTYVMEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKTQLNETHSKLQNEQTERKKVADDLHKAQQSLNFIHSKISLKAAGDTVVIENNDISPEMGSPEKETMSVSLTQTVAHLQQLLQEVNQQLTKEK", "length": 1325 }, "evidence": [ { "id": "A0A3Q1LVS2", "url": "https://omabrowser.org/oma/group/A0A3Q1LVS2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Z6P1-1", "protein_name": "Kinectin 1", "gene_name": "KTN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEFYESTYFIILIPSVVITVIFLFFWLFMKETLYDEVLAKQKRDLKFPPTKSDKKKTEKKKNKKKEAQNGNIHESDSESTPRDFKLSDALGTDEEQVGPVPLSATEASAGIRERKKKEKKQKAAQDDHVTKESEGSKSSGKKVEPVPVTKQPTPPSEPAAAKKKPGQKKQKNDDQDTKTDSVASPAKKQEPVLLHQEVKQENVSGKKKVSAKKQKVLVDEPLIQPTTYIPLVDNSDAGALEKREVVEVAKQNMNEGIQKSGGKKMKNETDKENAEVKFKDFVMAMKNMIFTEDEARCVVEVLKEKSGAIHDVLQKASKAESAAAIHQLQDKEKMLAAVKEEAAVAKEQCKQLTQELVAEKERNGLLTAKMRERINALEKEHGTFQSKIHVSYQESQQMKIKFQQRCEQMEAEISHLKQENTILRDAVSTSTNQMESKQAAELNKLRQDCARLVNELGEKNSKLQQEELQKKNAEQAVAQLKVQQQEAERRWEEIQVYLRKRTAEHEAAQQDVQNKLVAKDNEIQSLHSKLTDVVVSKQQLEQRMLQLIENEQKRASKEDSMQLRVQELVEQNDALNAQLQKLHSQMAAQVQHVLTLPFLFIAEKDKQLKQMEDSLGNEHANLTSKEEELKVLQNMNLSLKSEIQKLQALTNEQAAAAHELERMQKSIHIKDDKIRTLEEQLREELAQTVNTKEEFKILKDQNKTLQAEVQKLQALLSEPVQPTFEANKDLLEEMERGMRERDDKIKTVEELLEAGLIQMANKEEELKVLRTENSSLRKELQSLQIQLSEQVSFQSLVDELQKVIHEKDGKIKSVEELLQAEILKVANKEKTVQALTQKIEALKEEVGNSQLEMEKQVKHLSARSGKENQVKTMEALLEEKEKEIVQKGERLKGQQDTVAQLTSKVQELEQQNLQQLQQVPAASQVQDLESRLRGEEEQISKLKAVLEEKEREIASQVKQLQTMQSENESFKVQIQELKQENCKQVQLSIASLLVAGKEKEIASLQNELACQRNAFEQQRKKNNDLREKNWKAMEALASTEKLLQDKVNKTAKEKQQHVEAAEVETRELLQKLFPNVSLPANVSHSEWICGFEKMAKEYLRGASGSEDIKVMEQKLKEAEELHILLQLECEKYKSVLAETEGILQRLQRSVEEEESKWKIKVEESQKELKQMRSSVASLEHEVERLKEEIKEVETLKKEREHLESELEKAEIERSTYVSEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKMKLSETLSKLKVDQNERQKVAGDLPKAQESLASLEREIGKVVGDANVIENSDVRTESELTDKRLNVAVNLNQDVGHLKKLLVSVSQMLSKGREHYQLVGGCAGLGCCPVMMVALGLGLMRQVLKPEASHLEAFKARLDVALGSLVCWLVTLHIAGGWNWMSTVVLFNPGHSRIL", "length": 1426 }, "evidence": [ { "id": "A0A3Q1LVS2", "url": "https://omabrowser.org/oma/group/A0A3Q1LVS2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F049-1", "protein_name": "Kinectin isoform 1", "gene_name": "ktn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALDMADSQYLLILAPTLVIALMFLFFWLFMKETSYDEVLARQKRDMKLPPAKPDVRKKNEKKKNKKKESSGGGTGGGGGGGESEEDLRDFDTSDATSPTSNDEDSEALPVSPPAAPVQAEPPSGIRERKKKEKKPKSSPTAAPAVVPVVVPITRTTPTTTPALEEPEVNGSKSAVRKEQPILLTKQSSPPKPKASPPAPSETTSKKKAKKQKSEAEEHAPEVKPDPSPPVVKKEEPVITEVKTQDGAAPVSTAAPPTASSSSGRRKKKQKVEAAVTVDEAHVQSSALVIQIGSAAPTNHQNNQNNDTPPPVPAPAKHGKKQKSETNKENSEVKLKELLASIGGLVLSDSDVVSLVSLLREKSPNALDNWYKSTAKFEPTPQQLAEKDRLLNTLQEEASIAKGKVKQLSQELQAEKQKTGRVESVLHEHRVARDKDIMQAKAQSYQEMQIKFQQIREQLDGQIARLQQENGILRDAVERCSTTNQMETKQSSELNKLRSEYNSLMKELAETKNKLQQEELQRKGLEVNYKQNVSQLEDAKHRWEDLQNYLHSVNAEREKIQSELQNQIMVAESEMASKNKEIQSLHSSLKDTLMFKDQEQQKVLQLEQQVRQLLEASQRSMQPDDQLQEKVQDLLNENKTLKVQIDNLQTQLNTQATTVSHFEELQKLLAEKELQRKSLEDSLNAERSSGASRETNMQAMHNENHTLKAELQNLQAQISEKVVSVDQLQQSLQKRDEKTRTVENLLETSLIQVANKEDELKVVRNECEGLKQQLEAVQKQTTEQTVSEKALEELQLKIQEKDEQIKSVEGSLQLAVNKESERKKVVEDLQQQVEVLTAELAHLKTQESNSDLSAKLQELHAQLTAKDQDVERLQRELEKEMQPKQQTVSAAPSQELLTALAEKDKRLSDVQEELLELRESVELHRKKNNELREKNWSAMEALSATETILQGKLTKSAKEHQTVLESVEAECRALLHRLLPHIPLPSDQNHQQWVQKFEASVRESSSGEASSGDAQALAEKLKEAEEAQKVLQKDCETYKKVLAETEGILQRLQSSVEHEETRWREKLDLSQAELKEMTQRAIALDQEVDRLTSDADVESLRRDKQQLESELERAERESATYVSEVRELKDLLTELQSKLDGSYTEAVRQNEELNLLKTQLTETLCKLETEESERQKVAGDLYKAQQSLELIQEEIVKQAGQADLIETSGLTQMEEIDRKEKMTAGLNQTVQELQELLQSVNRQLTKGHERDDGDKLYSNYKL", "length": 1262 }, "evidence": [ { "id": "A0A3Q1LVS2", "url": "https://omabrowser.org/oma/group/A0A3Q1LVS2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q61595-1", "protein_name": "Kinectin", "gene_name": "Ktn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLISTKTDKKKAEKKKNKKKEIQNGTLRESDSEHVPRDFKLSDASPAEDEQFVPAPLNVAETSSSVRERQKKEKKQKPSLEEQVIKESDASKIPGKKVEPVLVTKQPAPPPPLEAAALKKKAGQKKSKNGSEEQDKKVEMLMAPSKEQDVLLSHQDTKQEGGLGKKKGLSKKQKSENVAVLVDEPLIHATTYMPLDNANSNLMMDKREIIDMIKPDHVEGIQKSGTKKLKIETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIKEALKKSNKGELSGLLHQLQEKERLLSAMKEDAAASKERCKRLTQEMMTEKERSSVVIARMKDRIGTLEKEHNIFQNKMHASYQETQQMQMKFQQVQEQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDCGRLVSELNEKTGKLQQEGVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRASKEESLQIQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQLKQTEDSLANEQDHLASKEEELKDVQNMNFLLKAEVQKWQALANEQAATAHEVEKMQKSIHVKEDEIRLLEEQLQHEVASKMEELKILSEQNKALQSEVRKLQTAVSQQPNKDVVEQMEKCIQEKDEKLRTVEELLETGLIQVATREEELSAIRTENSTLTREVQELKAKQSDQVSFVSLIEDLKRVIHEKDGQIKSVEELLEVELLKVANKEKTVQALKQEIEVLKEEIGNAQLEKAHQLSVTSQVQELQNLLRGKEEQVNSMKAALEDRDRGLTGRGTCAQVCSTPQFEELESVLKEKDNEIKRIEVKLKDTESDVSKMSELLKEVQEENKFLKCQLSHQKHQQASFPSQEELQTVISEKEKEITDLCNELESLKNAVEHQRKKNNDLREKNWEAMEALASTEKMLQDRVNKTSKERRQHVEAIELESKDLLKRLFPTVSVPSNLNYSEWLRGFEKKAKACVAGTSDAEAVKVLEHRLKEASEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEESKWKIKADESQRMIKQMQSSFTASERELERLRQENKDMENLRREREHLEMELEKAEMERSTYVMEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKTQLNETHSKLQNEQTERKKVADDLHKAQQSLNSIHSKISLKAAGDTVVIENSDISPEMESPEKETMSVSLNQTVTQLQQLLQEVNQQLTKET", "length": 1327 }, "evidence": [ { "id": "A0A3Q1LVS2", "url": "https://omabrowser.org/oma/group/A0A3Q1LVS2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86UP2-1", "protein_name": "Kinectin", "gene_name": "KTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFYESAYFIVLIPSIVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVETSSSVRERKKKEKKQKPVLEEQVIKESDASKIPGKKVEPVPVTKQPTPPSEAAASKKKPGQKKSKNGSDDQDKKVETLMVPSKRQEALPLHQETKQESGSGKKKASSKKQKTENVFVDEPLIHATTYIPLMDNADSSPVVDKREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE", "length": 1357 }, "evidence": [ { "id": "A0A3Q1LVS2", "url": "https://omabrowser.org/oma/group/A0A3Q1LVS2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1055, "end_pos": 1057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1088, "end_pos": 1090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1235, "end_pos": 1237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1301, "end_pos": 1303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LVS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVS2" }, { "id": "PF05104", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosome receptor lysine/proline rich", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 165, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1055, "end_pos": 1057 }, { "start_pos": 1088, "end_pos": 1090 }, { "start_pos": 1235, "end_pos": 1237 }, { "start_pos": 1301, "end_pos": 1303 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 772, "end_pos": 774 }, { "start_pos": 904, "end_pos": 906 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LNH2-1", "uniprot_ac": "A0A3Q1LNH2", "uniprot_id": "A0A3Q1LNH2_BOVIN", "mass": { "chemical_mass": 101469.0, "monoisotopic_mass": 101469.0 }, "refseq": { "ac": "XP_024832478", "name": "inositol-trisphosphate 3-kinase B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832478" }, "gene_names": [ { "name": "ITPKB", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ] }, { "name": "ITPKB", "type": "synonym", "evidence": [ { "id": "XP_024832478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832478" } ] } ], "protein_names": [ { "name": "Kinase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2/entry#names_and_taxonomy" } ] }, { "name": "2.7.-.-", "type": "synonym", "evidence": [ { "id": "A0A3Q1LNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2/entry#names_and_taxonomy" } ] }, { "name": "inositol-trisphosphate 3-kinase B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024832478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832478" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ITPKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2", "locus": { "chromosome": "16", "start_pos": 29641407, "end_pos": 29742136, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000053007", "url": "https://www.ensembl.org/id/ENSBTAG00000053007" } ] } } ], "crossref": [ { "id": "A0A3Q1LNH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000053007", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540877", "url": "https://www.ncbi.nlm.nih.gov/gene/540877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540877", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540877", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTKSWGD", "url": "https://omabrowser.org/oma/group/RTKSWGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNH2", "url": "https://www.orthodb.org/?gene=A0A3Q1LNH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12400:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12400:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024832478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832478", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11020", "url": "https://www.rhea-db.org/rhea/11020", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKL1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMYCYALNSLVIMNSANQVKSGGGPRSSSNETPPPPGRAVLSPGSVFSPGSGSSFLFPPAESLSPEDPGSPPGWRSGRRRLNSSSGSGSSVGSPSWAGRLRGEGQQMVTAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSATQPPRSPRLGRARSPSPCPLRSVSQPPGRVLVQSEERRTKSWGEQCPETSEVESGRRGGSPSVCLSKDKEGVVAPFLRPAAPSGSGAQGPSASERMEKALPAGPHCGSPTAMEVDKRGSPPLGTQNSQAPSLGLVRVNLTVDTAVAARATSTVPHHPHDPALIEPSEKARELGGAHPLEALAKSQGQFLGSETSPAPERGGPRSGEPPGKVGRGTLSDGMPSSRAPGADGRPEERTGNAQSPAEVPEAPTWFRQGSRGSAGTQSGALVVREAPPASNRVDEGSATLGLLGGSSSEQPGTPEVQAGVPSGGMLEPLPCWEAAKELKEPQYFPGDRVGVPPGTSRVWLSPMEEACLAWTCGTAVQSKGTWGGQPQGRDAHLSPERLSPAQKDKPSLGEACGRNSIPAVIITDMGTDADAQEDRALEEAQGSPRGSLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERCLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMADVLKPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGVRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVIEAFREFTKGNPNILIAYRDRLKDIRATLEISPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLIDILTEMCPSAPLA", "length": 942, "header": "tr|A0A3Q1LNH2-1|A0A3Q1LNH2_BOVIN Isoform 1 of Kinase OS=Bos taurus OX=9913 GN=ITPKB PE=3 SV=1 CANONICAL=A0A3Q1LNH2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2/entry", "sequence": { "sequence": "MAMYCYALNSLVIMNSANQVKSGGGPRSSSNETPPPPGRAVLSPGSVFSPGSGSSFLFPPAESLSPEDPGSPPGWRSGRRRLNSSSGSGSSVGSPSWAGRLRGEGQQMVTAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSATQPPRSPRLGRARSPSPCPLRSVSQPPGRVLVQSEERRTKSWGEQCPETSEVESGRRGGSPSVCLSKDKEGVVAPFLRPAAPSGSGAQGPSASERMEKALPAGPHCGSPTAMEVDKRGSPPLGTQNSQAPSLGLVRVNLTVDTAVAARATSTVPHHPHDPALIEPSEKARELGGAHPLEALAKSQGQFLGSETSPAPERGGPRSGEPPGKVGRGTLSDGMPSSRAPGADGRPEERTGNAQSPAEVPEAPTWFRQGSRGSAGTQSGALVVREAPPASNRVDEGSATLGLLGGSSSEQPGTPEVQAGVPSGGMLEPLPCWEAAKELKEPQYFPGDRVGVPPGTSRVWLSPMEEACLAWTCGTAVQSKGTWGGQPQGRDAHLSPERLSPAQKDKPSLGEACGRNSIPAVIITDMGTDADAQEDRALEEAQGSPRGSLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERCLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMADVLKPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGVRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVIEAFREFTKGNPNILIAYRDRLKDIRATLEISPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLIDILTEMCPSAPLA", "length": 942, "header": "tr|A0A3Q1LNH2-1|A0A3Q1LNH2_BOVIN Isoform 1 of Kinase OS=Bos taurus OX=9913 GN=ITPKB PE=3 SV=1 CANONICAL=A0A3Q1LNH2-1" }, "locus": { "chromosome": "16", "start_pos": 29741937, "end_pos": 29642411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070709.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070709.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058361.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058361.1" } ] } }, { "isoform_ac": "A0AAA9SKL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKL1/entry", "sequence": { "sequence": "MAMYCYALNSLVIMNSANQVKSGGGPRSSSNETPPPPGRAVLSPGSVFSPGSGSSFLFPPAESLSPEDPGSPPGWRSGRRRLNSSSGSGSSVGSPSWAGRLRGEGQQMVTAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSATQPPRSPRLGRARSPSPCPLRSVSQPPGRVLVQSEERRTKSWGEQCPETSEVESGRRGGSPSVCLSKDKEGVVAPFLRPAAPSGSGAQGPSASERMEKALPAGPHCGSPTAMEVDKRGSPPLGTQNSQAPSLGLVRVNLTVDTAVAARATSTVPHHPHDPALIEPSEKARELGGAHPLEALAKSQGQFLGSETSPAPERGGPRSGEPPGKVGRGTLSDGMPSSRAPGADGRPEERTGNAQSPAEVPEAPTWFRQGSRGSAGTQSGALVVREAPPASNRVDEGSATLGLLGGSSSEQPGTPEVQAGVPSGGMLEPLPCWEAAKELKEPQYFPGDRVGVPPGTSRVWLSPMEEACLAWTCGTAVQSKGTWGGQPQGRDAHLSPERLSPAQKDKPSLGEACGRNSIPAVIITDMGTDADAQEDRALEEAQGSPRGSLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERCLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMADVLKPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGVSEPGTQGTWRSAEPPHGEGCPFGQAGLLGTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVIEAFREFTKGNPNILIAYRDRLKDIRATLEISPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLIDILTEMCPSAPLA", "length": 970, "header": "tr|A0AAA9SKL1-1|A0A3Q1LNH2_BOVIN Computationally mapped isoform of Kinase OS=Bos taurus OX=9913 GN=ITPKB PE=3 SV=1 CANONICAL=A0A3Q1LNH2-1" }, "locus": { "chromosome": "16", "start_pos": 29741937, "end_pos": 29642411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109675.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109675.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085828.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085828.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:540877", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540877", "resource": "KEGG Pathway" }, { "id": "R-BTA-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "P27987-1", "protein_name": "Inositol-trisphosphate 3-kinase B", "gene_name": "ITPKB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLSPPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA", "length": 946 }, "evidence": [ { "id": "A0A3Q1LNH2", "url": "https://omabrowser.org/oma/group/A0A3Q1LNH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P42335-1", "protein_name": "Inositol-trisphosphate 3-kinase B", "gene_name": "Itpkb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVYCYALNSLVIMNSTNELKSGSPLPSGSETPQPSGRAALSPGSVFSPGRGASFLFPPAESLSLEEPGSAGGWRSGRRRLNSSSGSGGGSSSSNSSSSSGVGSPSWAGRLRGDAQQVVATRILSPPGPEEAQRKLRILQRELQNVQVNQKVGMFEAQIQAQTSAIQAPRSPRLGRARSPSPCPFRSSSQPPERVLAPCSPSEERRTKSWGEQCTETPDANSRRRSRLSTHPSKDKEGVAPLLGPASPTRLGTQSPSTSVRMERGSPASPRCGSPTPMEIDKRTAPSLEHFGTSLTLATKVAASAASAGPHPGHDSVLMEADCELGAMRPWEAHLERRGQFLGRETGSAPEPIRTHIREPPGRVERVHSVGGQGSWTPEVIKRPEEGTVDAQSSELSENPRWSRLPGDPGSVGPEKGGSRIPGIRGPQQTLDSMREGSSALGLLGGSQAAQPGSMDVETGISCGRMLEPLPPGEVTTNLKEPQCLPGDRMGMQPESSIVWPSAVEEAPLIWTCDTGIQLKGTWRSQDGDAHPSCQEKSPDQKDKACSPSNIPAIPAVIITDMGAQEDGGLEEIQGSPRGPLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVQWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMADVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMVEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVTEAFREFTKGNQNILIAYRDRLKAIRETLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLIDILTEMSQGSPLT", "length": 934 }, "evidence": [ { "id": "A0A3Q1LNH2", "url": "https://omabrowser.org/oma/group/A0A3Q1LNH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "inositol-1,4,5-trisphosphate 3-kinase activity", "id": "GO:0008440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008440", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "inositol hexakisphosphate kinase activity", "id": "GO:0000828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000828", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "inositol trisphosphate metabolic process", "id": "GO:0032957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032957", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" }, { "name": "inositol phosphate biosynthetic process", "id": "GO:0032958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032958", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11020", "name": "", "equation": "1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LNH2-1", "F1MN32-1" ], "evidence": [ { "id": "11020", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11020" } ] }, { "id": "R-BTA-1855153", "name": "I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-114520" ], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LNH2-1", "F1MN32-1" ], "evidence": [ { "id": "R-BTA-1855153", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855153" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-114520", "participant_name": "I(1,4,5)P3 [cytosol]", "crossref": [ { "id": "203600", "database": "ChEBI", "url": "" }, { "id": "ZINC000004095598", "database": "ZINC", "url": "" }, { "id": "C01245", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LNH2", "gene_name": "ITPKB", "activity": [ { "ec_number": "2.7.-.-", "activity": "", "evidence": [ { "id": "A0A3Q1LNH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH2" } ] } ] }, { "uniprot_ac": "F1MN32", "gene_name": "ITPKC", "activity": [ { "ec_number": "2.7.-.-", 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ4/entry#names_and_taxonomy" } ] }, { "name": "Chemokine-binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A3Q1LTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ4/entry#names_and_taxonomy" } ] }, { "name": "Chemokine-binding protein D6", "type": "synonym", "evidence": [ { "id": "A0A3Q1LTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ4/entry#names_and_taxonomy" } ] }, { "name": "atypical chemokine receptor 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059735594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059735594" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTZ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACKR2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ4", "locus": { "chromosome": "22", "start_pos": 14933475, "end_pos": 14891568, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014162", "url": "https://www.ensembl.org/id/ENSBTAG00000014162" } ] } } ], "crossref": [ { "id": "A0A3Q1LTZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LTZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014162", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014162", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512583", "url": "https://www.ncbi.nlm.nih.gov/gene/512583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000355", 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MMESPVVVHERWFASTLAAEPPLCFHHSTWWYPAHGKCWLNDSRLFLCRELQDWVRPPTMATTASPLPPTTKVASSENSSSFYDYEYYLEDMIFMLCRKDEVLSFGRVFLPVFYSLIFVLGLVGNLLLLAVLLRFVPRRRMTETYLLNLAISNLLFVVTLPFWGISVAWHWVFGSVLCKVVSTLYTVNFYSGIFFISCMSLDKYLEIVCARPYHRLRTRAKSLLLAASVWAMALAVSIPDMVFVRTHENSPGVWECYADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGSVLVSLRPPGQRRALRMAVALVVAFFVLWFPYNLTLFLHSLLDLQVFGDCRVSQHLDYALQVTESIAFLHCCFTPVLYAFSSHRFRQYLKAFLATVLRRQQALPSSYSESSGLTVQEDVMGMSDLGERPAESSPTRLSISSGLLRLDS", "length": 443, "header": "tr|A0A3Q1LTZ4-1|A0A3Q1LTZ4_BOVIN Isoform 1 of Atypical chemokine receptor 2 OS=Bos taurus OX=9913 GN=ACKR2 PE=4 SV=1 CANONICAL=A0A3Q1LTZ4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ4/entry", "sequence": { "sequence": "MMESPVVVHERWFASTLAAEPPLCFHHSTWWYPAHGKCWLNDSRLFLCRELQDWVRPPTMATTASPLPPTTKVASSENSSSFYDYEYYLEDMIFMLCRKDEVLSFGRVFLPVFYSLIFVLGLVGNLLLLAVLLRFVPRRRMTETYLLNLAISNLLFVVTLPFWGISVAWHWVFGSVLCKVVSTLYTVNFYSGIFFISCMSLDKYLEIVCARPYHRLRTRAKSLLLAASVWAMALAVSIPDMVFVRTHENSPGVWECYADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGSVLVSLRPPGQRRALRMAVALVVAFFVLWFPYNLTLFLHSLLDLQVFGDCRVSQHLDYALQVTESIAFLHCCFTPVLYAFSSHRFRQYLKAFLATVLRRQQALPSSYSESSGLTVQEDVMGMSDLGERPAESSPTRLSISSGLLRLDS", "length": 443, "header": "tr|A0A3Q1LTZ4-1|A0A3Q1LTZ4_BOVIN Isoform 1 of Atypical chemokine receptor 2 OS=Bos taurus OX=9913 GN=ACKR2 PE=4 SV=1 CANONICAL=A0A3Q1LTZ4-1" }, "locus": { "chromosome": "22", "start_pos": 14933163, "end_pos": 14895835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068509.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068509.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063967.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063967.1" } ] } }, { "isoform_ac": 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"id": "ENSBTAP00000085469.2", "url": "https://www.ensembl.org/id/ENSBTAP00000085469.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-380108", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380108", "resource": "Reactome", "description": "Chemokine receptors bind chemokines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BKA0-1", "protein_name": "Atypical chemokine receptor 2", "gene_name": "ACKR2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATSDSPLPLTTMVTSSENSSSFYDYEYYLDEAAFMLCRKDEVLSFGRVFLPIFYSLIFVLGLGGNLLLLVVLLWYVPRKRMTETYLLNLAISNLLFVVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFIGCMSLDKYLEIVWAWPHHQLRTRAKSLLLVTVVWVVALAVSIPDMVFVRTHENHPNVWDCYADFGGHGTIWKLFLRFQQNLLGFLLPLLAMTFFYARIGCVLVRLRPPGQGRALRMAVALVVAFFVLWFPYNLTLFLHSLLDLQVFGDCKVSQHLDYGLQVTESIAFLHCCITPVLYAFSSRRFRRHLKDLLAAVLRRHQAPYLAQAPPSSSSESSRLTAQEDVTRMNDLEGRQAEDAPNKENVGSSA", "length": 385 }, "evidence": [ { "id": "A0A3Q1LTZ4", "url": "https://omabrowser.org/oma/group/A0A3Q1LTZ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H979-1", "protein_name": "Atypical chemokine receptor 2", "gene_name": "Ackr2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPTKASSPTLTTTSPENSTFVYDYDYLDDVTILVCRKDAVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLRYVPRRQMVELYLLNLAISNLLFVVTMPFWAISVAWQWVFGNFLCKAVSILYTINFYCGIFFITCMSLDKYLEIVHAQPLHRLRPRFRSLLLITIVWTTALAVSVPEMVFVQAHQTLDGVWHCYADFGGHATVWKLYLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPPGQGRALRVATALVVAFFLLWFPYNLTLFLHSLLDLHILGNCQVSHYLDYTLQVTESLAFSHCCFTPFLYAFSSRRFRRYLKAFLAAVLRWHQEPDTAQARPPSYSESSRATAQEDVVSMNELGERQTDDPIDKADTGNDQA", "length": 383 }, "evidence": [ { "id": "A0A3Q1LTZ4", "url": "https://omabrowser.org/oma/group/A0A3Q1LTZ4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O00590-1", "protein_name": "Atypical chemokine receptor 2", "gene_name": "ACKR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATASPQPLATEDADSENSSFYYYDYLDEVAFMLCRKDAVVSFGKVFLPVFYSLIFVLGLSGNLLLLMVLLRYVPRRRMVEIYLLNLAISNLLFLVTLPFWGISVAWHWVFGSFLCKMVSTLYTINFYSGIFFISCMSLDKYLEIVHAQPYHRLRTRAKSLLLATIVWAVSLAVSIPDMVFVQTHENPKGVWNCHADFGGHGTIWKLFLRFQQNLLGFLLPLLAMIFFYSRIGCVLVRLRPAGQGRALKIAAALVVAFFVLWFPYNLTLFLHTLLDLQVFGNCEVSQHLDYALQVTESIAFLHCCFSPILYAFSSHRFRQYLKAFLAAVLGWHLAPGTAQASLSSCSESSILTAQEEMTGMNDLGERQSENYPNKEDVGNKSA", "length": 384 }, "evidence": [ { "id": "A0A3Q1LTZ4", "url": "https://omabrowser.org/oma/group/A0A3Q1LTZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O08707-1", "protein_name": "Atypical chemokine receptor 2", "gene_name": "Ackr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTVASPLPLTTVGSENSSSIYDYDYLDDMTILVCRKDEVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLHSAPRRRTMELYLLNLAVSNLLFVVTMPFWAISVAWHWVFGSFLCKVISTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKAQFRNLLLIVMVWITSLAISVPEMVFVQIHQTLDGVWHCYADFGGHATIWKLYLRFQLNLLGFLLPLLAMIFFYSRIGCVLVRLRPPGQGRALRMAAALVIVFFMLWFPYNLTLFLHSLLDLHVFGNCEISHRLDYTLQVTESLAFSHCCFTPVLYAFCSHRFRRYLKAFLSVMLRWHQAPGTPSSNHSESSRVTAQEDVVSMNDLGERQSEDSLNKGEMGNT", "length": 378 }, "evidence": [ { "id": "A0A3Q1LTZ4", "url": "https://omabrowser.org/oma/group/A0A3Q1LTZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O09027-1", "protein_name": "Atypical chemokine receptor 2", "gene_name": "Ackr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 373, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": 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"MKRPCVWKMLMAAMCVALLSGLQAQDLPRQVSIILLGATGDLARKYLWQGLFHLYLEEVGKGHHFRFHGTALTSTEQGQEVIAKVLESLSCPGDMASGHCAELKAQFQQLSEYRQLKTPEDYVALSKDIEAQVEHEGLRETGRIFYLSVPPFAYVDIARNINSSCRPGPGAWLRVVLEKPFGHDLHSAQQLATELGSFFQEEEMYRVDHYLGKQVVAQILPFRDQNRAALDGLWNRHHVERVEIVMKETLDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPVNVSSPESVLQHKLQAFQALRSLQRHSAVLGQYQAYSGQVRRELQKPDSFHSLTPTFAGILVHIDNLRWEGVPFILMSGKALDERVSYVRILFKNQAFCVQSEKHWVAAQSHCLPRQIIFYIGHGELGSPAVLVSRNLFQPALPSASWKEVEGRPGLHLFGLPLSDYYAYSPVREQDAYSLLISHIFHCRKDSFVTTENLLASWVFWTPLLDSLAHEVPRFYPGGAENGQLLDFEFSGGHLSFSQPLPEQLVPGPDSAPLPSDFQVLRAKYRESPLISAWPEELIARLAGDIEAAAVRAVRRFGKFHLALSGGSSPVALFQQLATGHYSFPWAHTHLWLVDERCVPLWDPESNFQGLQTHLLQHVRVPHYNVHPMPVHRRQRLCAEEDQGAQAYAEEISALVTNGSFDLVLLGMGTDGHTASLFPQSPAGLDGEQLVVLTTSPSSPHRRMSLSLPLINRARKVAVLVMGRMKREIAMLVSRVGRDPKKWPISGVLPDSGQLVWYMDYDAFLG", "length": 797, "header": "tr|A0A3Q1LRN7-1|A0A3Q1LRN7_BOVIN Isoform 1 of GDH/6PGL endoplasmic bifunctional protein OS=Bos taurus OX=9913 GN=SPSB1 PE=1 SV=2 CANONICAL=A0A3Q1LRN7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7/entry", "sequence": { "sequence": "MKRPCVWKMLMAAMCVALLSGLQAQDLPRQVSIILLGATGDLARKYLWQGLFHLYLEEVGKGHHFRFHGTALTSTEQGQEVIAKVLESLSCPGDMASGHCAELKAQFQQLSEYRQLKTPEDYVALSKDIEAQVEHEGLRETGRIFYLSVPPFAYVDIARNINSSCRPGPGAWLRVVLEKPFGHDLHSAQQLATELGSFFQEEEMYRVDHYLGKQVVAQILPFRDQNRAALDGLWNRHHVERVEIVMKETLDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPVNVSSPESVLQHKLQAFQALRSLQRHSAVLGQYQAYSGQVRRELQKPDSFHSLTPTFAGILVHIDNLRWEGVPFILMSGKALDERVSYVRILFKNQAFCVQSEKHWVAAQSHCLPRQIIFYIGHGELGSPAVLVSRNLFQPALPSASWKEVEGRPGLHLFGLPLSDYYAYSPVREQDAYSLLISHIFHCRKDSFVTTENLLASWVFWTPLLDSLAHEVPRFYPGGAENGQLLDFEFSGGHLSFSQPLPEQLVPGPDSAPLPSDFQVLRAKYRESPLISAWPEELIARLAGDIEAAAVRAVRRFGKFHLALSGGSSPVALFQQLATGHYSFPWAHTHLWLVDERCVPLWDPESNFQGLQTHLLQHVRVPHYNVHPMPVHRRQRLCAEEDQGAQAYAEEISALVTNGSFDLVLLGMGTDGHTASLFPQSPAGLDGEQLVVLTTSPSSPHRRMSLSLPLINRARKVAVLVMGRMKREIAMLVSRVGRDPKKWPISGVLPDSGQLVWYMDYDAFLG", "length": 797, "header": "tr|A0A3Q1LRN7-1|A0A3Q1LRN7_BOVIN Isoform 1 of GDH/6PGL endoplasmic bifunctional protein OS=Bos taurus OX=9913 GN=SPSB1 PE=1 SV=2 CANONICAL=A0A3Q1LRN7-1" }, "locus": { "chromosome": "16", "start_pos": 44242709, "end_pos": 44209995, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075807.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075807.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059834.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059834.2" } ] } }, { "isoform_ac": "A0AAA9SPV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPV0/entry", "sequence": { "sequence": "MLAEPHFKRRPCVWKMLMAAMCVALLSGLQAQDLPRQVSIILLGATGDLARKYLWQGLFHLYLEEVGKGHHFRFHGTALTSTEQGQEVIAKVLESLSCPGDMASGHCAELKAQFQQLSEYRQLKTPEDYVALSKDIEAQVEHEGLRETGRIFYLSVPPFAYVDIARNINSSCRPGPGAWLRVVLEKPFGHDLHSAQQLATELGSFFQEEEMYRVDHYLGKQVVAQILPFRDQNRAALDGLWNRHHVERVEIVMKETLDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPVNVSSPESVLQHKLQAFQALRSLQRHSAVLGQYQAYSGQVRRELQKPDSFHSLTPTFAGILVHIDNLRWEGVPFILMSGKALDERVSYVRILFKNQAFCVQSEKHWVAAQSHCLPRQIIFYIGHGELGSPAVLVSRNLFQPALPSASWKEVEGRPGLHLFGLPLSDYYAYSPVREQDAYSLLISHIFHCRKDSFVTTENLLASWVFWTPLLDSLAHEVPRFYPGGAENGQLLDFEFSGGHLSFSQPLPEQLVPGPDSAPLPSDFQVLRAKYRESPLISAWPEELIARLAGDIEAAAVRAVRRFGKFHLALSGGSSPVALFQQLATGHYSFPWAHTHLWLVDERCVPLWDPESNFQGLQTHLLQHVRVPHYNVHPMPVHRRQRLCAEEDQGAQAYAEEISALVTNGSFDLVLLGMGTDGHTASLFPQSPAGLDGEQLVVLTTSPSSPHRRMSLSLPLINRARKVAVLVMGRMKREIAMLVSRVGRDPKKWPISGVLPDSGQLVWYMDYDAFLG", "length": 804, "header": "tr|A0AAA9SPV0-1|A0A3Q1LRN7_BOVIN Computationally mapped isoform of GDH/6PGL endoplasmic bifunctional protein OS=Bos taurus OX=9913 GN=SPSB1 PE=1 SV=1 CANONICAL=A0A3Q1LRN7-1" }, "locus": { "chromosome": "16", "start_pos": 44234164, "end_pos": 44209995, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102247.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102247.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084953.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084953.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z832-1", "protein_name": "GDH/6PGL endoplasmic bifunctional protein", "gene_name": "H6PD", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRRVLCTMLLMGALPSLAEASQGHISVVLLGATGDLAKKYLWQGLFQLYIDQVSSGHSFTFHGAALTDLEPGQKLMFDVLKKLACPPDESPNRCAVLKDQFLKLSQYHQLKTSENYTALNREIEMLLHQEGLKEAGRIFYFSVPPFAYTEIARHINSSCRPPPGAWLRVVLEKPFGHDLESAQQMAAELMSFFREEEMYRVDHYLGKQAVAHILPFRDQNRQFLDPIWNRHHVERVEIVLKEIVDAKGRTSFYEQYGVIRDVLQNHLTEALMFLTMELPGNLSKAEEVLQCKLQALQSLRGLEKQSVVVGQYQAYASHVQEELQKGQDYVSTTPTFAGVLVHSDSLRWEGVPFLLTSGKALDERVGYVRVLFKNRAYCTQSEALRDAGHSQCKPKQIVFYIGHGALNTPAVLVSRNLFRPIMPKSTWREVVGQPDLHVFGQLLSDYYMYSPVKERDAYSVLISNIYHGRKDFFITTENLLASWAFWTPLLNSISHQAPRLYPGGVENQHFLDFEMMSGELAFTVAEPVELLNPSGPMPSDYKTIQSKFRQSPLVSAWSEVLISQLASDVEKTASRAVARSGQFHLALSGGSSPVALFQRLARHHYDFPWRHTHLWLVDERCVPLTDPESNFFSLHNHLLQNIRVPYFNVHPMPVHLHQRLCVEEDGGPELYAKEIMALVANASFDLVLLGVGTDGHTASLFPHSENGLEGAQAVVLTESPVKPHQRMSLSLPLINKAQQVFVLVMGKGKHDITTQISRVGHEPRKWPISGVNPSSGQLVWYVDYEALLG", "length": 790 }, "evidence": [ { "id": "A0A3Q1LRN7", "url": "https://omabrowser.org/oma/group/A0A3Q1LRN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A7D7-1", "protein_name": "GDH/6PGL endoplasmic bifunctional protein", "gene_name": "H6pd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKCTGIWKMLVAAVCLALLGCLQAQEFRGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKALESLSCPKDLVPSRCDELKAQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGVIRDTLQNHLTEILTLVAMELPPNISSSAAVLQHKLQAFQALRGLQKSNAILGQYQAYSGQVRQELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNRAYCTQGERHWVPERSRCLPQQIVFYIGHGELGHPAILVSKNLFKPSLPAQSWKGVQDQPGLHLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLSFEVPRLYPGGAENDHLLDFEFSGGQLTFSQQQLEVLMPELGSVPKPSDFQVLRAQYRKSPLITAWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPRGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG", "length": 797 }, "evidence": [ { "id": "A0A3Q1LRN7", "url": "https://omabrowser.org/oma/group/A0A3Q1LRN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FGT2-1", "protein_name": "GDH/6PGL endoplasmic bifunctional protein", "gene_name": "h6pd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRIRWELLLMAIICGQRGSADNHEAKQSLGHVTVVVVGGTGDLARKYLWQGFFQLYADQVGKGHSFSFYGGGLSPAEKGTPVLFGILKELACPPELTAERCALVKEQFLHLSRYHQLKTAEDYEKLCQQIKQQVGQESMTEAGRLFYLSVPAFAYAEIAERINNTCRPPSDAWLRVVLEKPFGHDFASAQLLDKKLSGQLKEEEMYRIDHYLGKQVVSKILPFRKENKKLLDPIWNKHHIERIEIVLKETLDAKGRIQFYDQYGVIRDVLQNHLTEVMTLMLMNLPANLSNSKEILLNKLHFLASLQHIDNSNAVVGQYQAYNGEVQAELNKTKDYFSLTPTFAGVVIHVDNAQYEGIPIFMTSGKALDERVSYARVLFKSDVFCVQDPNNVQCKSKQIIFYLGHGNLQYPSILVSKNLLKPEIVSSGDWKEVTEYKEVNLLGLPLSDYYIQSPVAPREAYGELISHVFFGRKDSFISAEGLLASWAFWTPLLESLSHVYPRIYPGGVSNGNLLNFQLRGHQIAFSHEAVVNVINRGAEENFQVMQGKYRSSEMISAWAQELVERLASDLLLAAEEAIRREGQFHLALSGGSSPVALLRALALNLYTFPWRNTHIWQVDERCVPHTESGSNFRSIHDLLLQHIRIPYFNIHPMPVHLTQRLCVEEDGGATLYEKEIQKHVNASSFHYILLGVGQDGHTASLFQDTKLESDGERLVTLTESPIKPHQRMSLTFTAINKARRVGVLVMGKSKHELVTQLSRIKGESSRYPITKVQPNNGSLIWYIDYDALLG", "length": 791 }, "evidence": [ { "id": "A0A3Q1LRN7", "url": "https://omabrowser.org/oma/group/A0A3Q1LRN7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95479-1", "protein_name": "GDH/6PGL endoplasmic bifunctional protein", "gene_name": "H6PD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWNMLIVAMCLALLGCLQAQELQGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGRGHSFSFHGAALTAPKQGQELMAKALESLSCPKDMAPSHCAEHKDQFLQLSQYRQLKTAEDYQALNKDIEAQLQHAGLREAGRIFYFSVPPFAYEDIARNINSSCRPGPGAWLRVVLEKPFGHDHFSAQQLATELGTFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIIMKETVDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPHNVSSAEAVLRHKLQVFQALRGLQRGSAVVGQYQSYSEQVRRELQKPDSFHSLTPTFAAVLVHIDNLRWEGVPFILMSGKALDERVGYARILFKNQACCVQSEKHWAAAQSQCLPRQLVFHIGHGDLGSPAVLVSRNLFRPSLPSSWKEMEGPPGLRLFGSPLSDYYAYSPVRERDAHSVLLSHIFHGRKNFFITTENLLASWNFWTPLLESLAHKAPRLYPGGAENGRLLDFEFSSGRLFFSQQQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAWSEELISKLANDIEATAVRAVRRFGQFHLALSGGSSPVALFQQLATAHYGFPWAHTHLWLVDERCVPLSDPESNFQGLQAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSSFDLVLLGMGADGHTASLFPQSPTGLDGEQLVVLTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKREITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG", "length": 791 }, "evidence": [ { "id": "A0A3Q1LRN7", "url": "https://omabrowser.org/oma/group/A0A3Q1LRN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CFX1-1", "protein_name": "GDH/6PGL endoplasmic bifunctional protein", "gene_name": "H6pd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLAAMCLALLGCLQAQELKGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKVLESLSCPKDLVPSRCDELKGQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRIFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETIDAEGRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAAVLQHKLWAFQALRGLQKSSAILGQYQAYSGQVRRELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNRAYCTQSERHWVPEQSRCLPQQIIFYIGHGELGHPAILVSRNLFKPSLPTQKWKEVQDQPGLRLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLAFEVPRPYPGGAENGQLLDFEFSGGQLTFSQQQLEVLIPDLGSVPKPSDFQVLGARYRQSPLITAWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPTGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG", "length": 789 }, "evidence": [ { "id": "A0A3Q1LRN7", "url": "https://omabrowser.org/oma/group/A0A3Q1LRN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "pentose-phosphate shunt, oxidative branch", "id": "GO:0009051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009051", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" }, { "name": "regulation of cortisol biosynthetic process", "id": "GO:2000064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000064", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "6-phosphogluconolactonase activity", "id": "GO:0017057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017057", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" }, { "name": "glucose-6-phosphate dehydrogenase activity", "id": "GO:0004345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004345", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" }, { "name": "glucose 1-dehydrogenase [NAD(P)+] activity", "id": "GO:0047936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047936", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12556", "name": "", "equation": "6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MM83-1", "Q2TBQ8-1", "A0A3Q1LRN7-1" ], "evidence": [ { "id": "12556", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12556" } ] }, { "id": "14293", "name": "", "equation": "D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "14293", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14293" } ] }, { "id": "14405", "name": "", "equation": "D-glucose + NADP(+) = D-glucono-1,5-lactone + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1", "Q148L6-1" ], "evidence": [ { "id": "14405", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14405" } ] }, { "id": "15841", "name": "", "equation": "D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SCJ6-1", "A0A3Q1LRN7-1" ], "evidence": [ { "id": "15841", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15841" } ] }, { "id": "38215", "name": "", "equation": "D-glucose 6-phosphate + NAD(+) = 6-phospho-D-glucono-1,5-lactone + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "38215", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38215" } ] }, { "id": "62064", "name": "", "equation": "2-deoxy-D-glucose 6-phosphate + NAD(+) = 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "62064", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62064" } ] }, { "id": "62068", "name": "", "equation": "2-deoxy-D-glucose 6-phosphate + NADP(+) = 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "62068", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62068" } ] }, { "id": "62072", "name": "", "equation": "D-galactose 6-phosphate + NADP(+) = 6-phospho-D-galactono-1,5-lactone + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "62072", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62072" } ] }, { "id": "62076", "name": "", "equation": "D-galactose 6-phosphate + NAD(+) = 6-phospho-D-galactono-1,5-lactone + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "62076", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62076" } ] }, { "id": "62080", "name": "", "equation": "D-glucose 6-sulfate + NADP(+) = 6-sulfo-D-glucono-1,5-lactone + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "62080", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62080" } ] }, { "id": "62088", "name": "", "equation": "D-glucosamine 6-phosphate + NADP(+) = 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRN7-1" ], "evidence": [ { "id": "62088", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62088" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LRN7", "gene_name": "SPSB1", "activity": [ { "ec_number": "3.1.1.31", "activity": "6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+).", "evidence": [ { "id": "A0A3Q1LRN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ] }, { "ec_number": "1.1.1.47", "activity": "D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH + H(+).", "evidence": [ { "id": "A0A3Q1LRN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRN7" } ] }, { "ec_number": "1.1.1.363", "activity": "D-glucose 6-phosphate + NAD(+) = 6-phospho-D-glucono-1,5-lactone + NADH + H(+).", "evidence": [ { "id": "A0A3Q1LRN7", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LRB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQX2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQX2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUI1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ML70", "url": "https://www.uniprot.org/uniprotkb/F1ML70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ML70-1", "url": "https://www.uniprot.org/uniprotkb/F1ML70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYIQLEPLNEGFLSRISDLLLCRWTCHHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLLASRSSDKDGDSVHTASDVPLTPRTNSPDRRCSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDDYFRKFEPRLYSLDSNSDDVDFLTDAEILSKYQLGMLHFSTQYDLLHNRLTVRVIEARDLPPPISHDGARQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVLDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLSAHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 474, "header": "tr|A0A3Q1LRB0-1|A0A3Q1LRB0_BOVIN Isoform 1 of Synaptotagmin-17 OS=Bos taurus OX=9913 GN=SYT17 PE=3 SV=1 CANONICAL=A0A3Q1LRB0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0/entry", "sequence": { "sequence": "MAYIQLEPLNEGFLSRISDLLLCRWTCHHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLLASRSSDKDGDSVHTASDVPLTPRTNSPDRRCSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDDYFRKFEPRLYSLDSNSDDVDFLTDAEILSKYQLGMLHFSTQYDLLHNRLTVRVIEARDLPPPISHDGARQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVLDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLSAHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 474, "header": "tr|A0A3Q1LRB0-1|A0A3Q1LRB0_BOVIN Isoform 1 of Synaptotagmin-17 OS=Bos taurus OX=9913 GN=SYT17 PE=3 SV=1 CANONICAL=A0A3Q1LRB0-1" }, "locus": { "chromosome": "25", "start_pos": 16799124, "end_pos": 16712168, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083062.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083062.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059660.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059660.1" } ] } }, { "isoform_ac": "A0AAA9SQX2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQX2/entry", "sequence": { "sequence": "MLKFPIYSVLVSQEATSSPEGSSTLLGGQLPSQDGQLEPLNEGFLSRISDLLLCRWTCHHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLLASRSSDKDGDSVHTASDVPLTPRTNSPDRRCSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDDYFRKFEPRLYSLDSNSDDVDFLTDAEILSKYQLGMLHFSTQYDLLHNRLTVRVIEARDLPPPISHDGARQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVLDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLSAHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 505, "header": "tr|A0AAA9SQX2-1|A0A3Q1LRB0_BOVIN Computationally mapped isoform of Synaptotagmin-17 OS=Bos taurus OX=9913 GN=SYT17 PE=3 SV=1 CANONICAL=A0A3Q1LRB0-1" }, "locus": { "chromosome": "25", "start_pos": 16795809, "end_pos": 16712168, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102165.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102165.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086445.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086445.1" } ] } }, { "isoform_ac": "A0AAA9SUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUI1/entry", "sequence": { "sequence": "MRRVDSLEKTLMLGEIAGRRRRGRQRMRWLDGITDSMDLEPLNEGFLSRISDLLLCRWTCHHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLLASRSSDKDGDSVHTASDVPLTPRTNSPDRRCSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDDYFRKFEPRLYSLDSNSDDVDFLTDAEILSKYQLGMLHFSTQYDLLHNRLTVRVIEARDLPPPISHDGARQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVLDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLSAHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 507, "header": "tr|A0AAA9SUI1-1|A0A3Q1LRB0_BOVIN Computationally mapped isoform of Synaptotagmin-17 OS=Bos taurus OX=9913 GN=SYT17 PE=3 SV=1 CANONICAL=A0A3Q1LRB0-1" }, "locus": { "chromosome": "25", "start_pos": 16805343, "end_pos": 16712168, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120238.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120238.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089000.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089000.1" } ] } }, { "isoform_ac": "F1ML70-1", "url": "https://www.uniprot.org/uniprotkb/F1ML70/entry", "sequence": { "sequence": "MGRTLPAPDSAAGWTVPFQLHGRPGGPALGQLEPLNEGFLSRISDLLLCRWTCHHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLLASRSSDKDGDSVHTASDVPLTPRTNSPDRRCSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDDYFRKFEPRLYSLDSNSDDVDFLTDAEILSKYQLGMLHFSTQYDLLHNRLTVRVIEARDLPPPISHDGARQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVLDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLSAHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 500, "header": "tr|F1ML70-1|F1ML70_BOVIN Computationally mapped isoform of Synaptotagmin-17 OS=Bos taurus OX=9913 GN=SYT17 PE=3 SV=4 CANONICAL=A0A3Q1LRB0-1" }, "locus": { "chromosome": "25", "start_pos": 16799714, "end_pos": 16712168, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018914.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018914.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018914.7", "url": "https://www.ensembl.org/id/ENSBTAP00000018914.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532273", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532273", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PSH0-1", "protein_name": "Synaptotagmin-17", "gene_name": "SYT17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAYIQLEPINEGLLARISDLLLCRWTCRNCCQKCFDCSCCQTNEDEVEILGPFPAQTPAWLISSQNEDKNGDSDNTISDLPPTLQDVSPDRRRSSSDTSRSTYSLTRRISSLESRRPSSPLIDIKPIEFGIIGAKKEIVQPTILRKTYSPDDYFRKFEPRLYSLDSNSDDMDSLTDEEILSKYQLGMLHFSTQYDLLHNYLIVRVIEAKDLPPPISYDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQNPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSMPLGDVDLVKGGHWWKALVPSSQNEVELGELLLSLNYLPSAGRLNVDIIRAKQLLQTDMSQGSDPFVKIQLVHGLKLTKTKKTSCMRGTIDPFYNESFSFKVPQEELENASLVFTVYGHNVKSSNDFIGRIVIGQYSTGAPESNHWRRMLNAHRTAVEQWHSLRSREECDRVSPASLEVT", "length": 474 }, "evidence": [ { "id": "A0A3Q1LRB0", "url": "https://omabrowser.org/oma/group/A0A3Q1LRB0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q62807-1", "protein_name": "Synaptotagmin-17", "gene_name": "Syt17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYIQLEPLNEGFLSRISDVLLCGWTCQHCCQRCYESSCCQSSEDEVEILGPFPAQTPPWLMASRSNDKDGDSVHTASDVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLDSRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDDYFRKFEPRLYSLDSNLDDVDSLTDEEIMSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDIIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 474 }, "evidence": [ { "id": "A0A3Q1LRB0", "url": "https://omabrowser.org/oma/group/A0A3Q1LRB0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920M7-1", "protein_name": "Synaptotagmin-17", "gene_name": "Syt17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLEPLNEGLLSRISDVLLCGWTCQHCCQRCYESSCCQSSEDEVEILGPFPAQTPPWLMASRSNDKDGDSVHTASDVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLDSRRPSSPLIDIKPVEFGVLSAKKESIQPSVLRRTYTPDDYFRKFEPRLYSLDSNLDDVDSLTDEEIMSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDIIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 470 }, "evidence": [ { "id": "A0A3Q1LRB0", "url": "https://omabrowser.org/oma/group/A0A3Q1LRB0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BSW7-1", "protein_name": "Synaptotagmin-17", "gene_name": "SYT17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYIQLEPLNEGFLSRISGLLLCRWTCRHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLMASRSSDKDGDSVHTASEVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT", "length": 474 }, "evidence": [ { "id": "A0A3Q1LRB0", "url": "https://omabrowser.org/oma/group/A0A3Q1LRB0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "regulation of postsynaptic neurotransmitter receptor internalization", "id": "GO:0099149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099149", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LRB0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LRB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRB0" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 310, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 389, "end_pos": 391 }, { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LNK7-1", "uniprot_ac": "A0A3Q1LNK7", "uniprot_id": "A0A3Q1LNK7_BOVIN", "mass": { "chemical_mass": 70825.0, "monoisotopic_mass": 70825.0 }, "refseq": { "ac": 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"MGKMAAEKQVPGGGGSGGSSGGGSGGSGGGRSAGGEENKENERPSAGSKAHKEFGDSLSLEILQIIKESQQQHGLRHGDFQRYRGYCSRRQRRLRKTLNFKMGNRHKFTGKKVTEDLLTDNRYLLLVLMDAERAWSYAMQLKQEANTEPRKRFHLLSRLRKAVKHAEELERLCESNRVDAKTKLEAQAYTAYLSGMLRFEHQEWKAAIEAFNKCKTIYEKLASAFTEEQAVLYNQRVEEISPNIRYCAYNIGDQSAINELMQMRLRSGGTEGLLAEKLEALITQTRAKQAATMSEVEWRGRTVPVKIDKVRIFLLGLADNEAAIAQAESEETKERLFESMLSECRDAIQAVREELKSDQKQRDYALDVESGKVSNLQYLHSYLTYIKLSTAIKRNENMAKGLQKALLQQQPEDDSKRAPRPQDLIRLYDIILQNLVELLQLPGLEEDRAFQKEIGLKTLVYKAYRCFFIAQSYVLVKKWNEALVLYDRVLKYADEVNSDAGAFKNSLKDLPDVQELITQVRSEKCSLQAAAILDTNDAHQTETSSQVKDNKPLVERFETFCLDPSLVTKQANLVHFPPGFQPIPCKPLFFDLALNHVAFPPLEDKLEQKAKSGLTGYIKGIFGFRS", "length": 626, "header": "tr|A0A3Q1LNK7-1|A0A3Q1LNK7_BOVIN Isoform 1 of Signal recognition particle subunit SRP68 OS=Bos taurus OX=9913 GN=SRP68 PE=3 SV=2 CANONICAL=A0A3Q1LNK7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNK7/entry", "sequence": { "sequence": 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recognition particle subunit SRP68 OS=Bos taurus OX=9913 GN=SRP68 PE=3 SV=1 CANONICAL=A0A3Q1LNK7-1" }, "locus": { "chromosome": "19", "start_pos": 55616532, "end_pos": 55592410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118393.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118393.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096870.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096870.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538777", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538777", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "signal recognition particle binding", "id": "GO:0005047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005047", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNK7", 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"evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNK7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNK7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNK7" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNK7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209355" } ] } ], "protein_names": [ { "name": "Transcription factor E2-alpha", "type": "recommended", "evidence": [ { "id": "A0A3Q1LQN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor 3", "type": "synonym", "evidence": [ { "id": "A0A3Q1LQN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2/entry#names_and_taxonomy" } ] }, { "name": "transcription factor E2-alpha isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005209355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209355" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TCF3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2", "locus": { "chromosome": "7", "start_pos": 43982979, "end_pos": 44014944, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008695", "url": "https://www.ensembl.org/id/ENSBTAG00000008695" } ] } } ], "crossref": [ { "id": "A0A3Q1LQN2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LQN2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008695", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008695", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18943", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18943", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18945", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18945", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "530616", "url": "https://www.ncbi.nlm.nih.gov/gene/530616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FPQPHCL", "url": "https://omabrowser.org/oma/group/FPQPHCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPQ4", "url": "https://www.orthodb.org/?gene=A0A3Q1LPQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQN2", "url": "https://www.orthodb.org/?gene=A0A3Q1LQN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MVI6", "url": "https://www.orthodb.org/?gene=F1MVI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11793:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11793:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-525793", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-525793", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8939236", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005209355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209355", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVE4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVE4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MVI6", "url": "https://www.uniprot.org/uniprotkb/F1MVI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MVI6-1", "url": "https://www.uniprot.org/uniprotkb/F1MVI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQSQRMAPVGTDKELSDLLDFSMMFPLPVANGKSRPASLAGTQFGSSGLEDRPSSGSWGTSEQDSSSFDPGRTYSDGAHFGESHSSLPSSTFLGPGLGGKGSERGAYAAFGRDAGVSSLTQVGFLPSELALSSPGPLSPSGIKGGSQYYSYSGHPRRRATDSSLDSQPKKVRKVPPGLPSSVYPPSSGDDYGRDPTTYPSAKTPSSSYPTPFYMADGSLHPSAELWSAPGQAGFGPMLGGGSSPLPLPAGGGSSVGGSGGFGSLHQHERMGYQLHGAEVNGGLPAASTFSGPAGTYSSISSHTPPVSGADSLLGSRGTTSSSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRPGAPGALSPSYDGGLHGLQSKVEDHLDEAIHVLRSHAVGTAGDVHGLLPGHGALTSGFAGPVMPLGGRHAGLVGSGHSEDGLSGSSGLVHNHVALPDLSRQPDSYGDLGHGTAPGTTDIKREEQEDEENVAADTAEDEKKDLKAPRTRSSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAAHPGLGEAHNPAGHL", "length": 642, "header": "tr|A0A3Q1LQN2-1|A0A3Q1LQN2_BOVIN Isoform 1 of Transcription factor E2-alpha OS=Bos taurus OX=9913 GN=TCF3 PE=4 SV=1 CANONICAL=A0A3Q1LQN2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ4/entry", "sequence": { "sequence": "MNQSQRMAPVGTDKELSDLLDFSMMFPLPVANGKSRPASLAGTQFGSSGLEDRPSSGSWGTSEQDSSSFDPGRTYSDGAHFGESHSSLPSSTFLGPGLGGKGSERGAYAAFGRDAGVSSLTQVGFLPSELALSSPGPLSPSGIKGGSQYYSYSGHPRRRATDSSLDSQPKKVRKVPPGLPSSVYPPSSGDDYGRDPTTYPSAKTPSSSYPTPFYMADGSLHPSAELWSAPGQAGFGPMLGGGSSPLPLPAGGGSSVGGSGGFGSLHQHERMGYQLHGAEVNGGLPAASTFSGPAGTYSSISSHTPPVSGADSLLGSRGTTSSSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRPGAPGALSPSYDGGLHGLQSKVEDHLDEAIHVLRSHAVGTAGDVHGLLPGHGALTSGFAGPVMPLGGRHAGLVGSGHSEDGLSGSSGLVHNHVALPDLSRQPDSYGDLGHGTAPGTTDIKREEQEDEENVAADTAEDEKKDLKAPRTRSSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRAVRRRCCPWRRKT", "length": 608, "header": "tr|A0A3Q1LPQ4-1|A0A3Q1LQN2_BOVIN Computationally mapped isoform of Transcription factor E2-alpha OS=Bos taurus OX=9913 GN=TCF3 PE=4 SV=1 CANONICAL=A0A3Q1LQN2-1" }, "locus": { "chromosome": "7", "start_pos": 44012809, "end_pos": 43984499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068062.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068062.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062076.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062076.1" } ] } }, { "isoform_ac": "A0A3Q1LQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2/entry", "sequence": { "sequence": "MNQSQRMAPVGTDKELSDLLDFSMMFPLPVANGKSRPASLAGTQFGSSGLEDRPSSGSWGTSEQDSSSFDPGRTYSDGAHFGESHSSLPSSTFLGPGLGGKGSERGAYAAFGRDAGVSSLTQVGFLPSELALSSPGPLSPSGIKGGSQYYSYSGHPRRRATDSSLDSQPKKVRKVPPGLPSSVYPPSSGDDYGRDPTTYPSAKTPSSSYPTPFYMADGSLHPSAELWSAPGQAGFGPMLGGGSSPLPLPAGGGSSVGGSGGFGSLHQHERMGYQLHGAEVNGGLPAASTFSGPAGTYSSISSHTPPVSGADSLLGSRGTTSSSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRPGAPGALSPSYDGGLHGLQSKVEDHLDEAIHVLRSHAVGTAGDVHGLLPGHGALTSGFAGPVMPLGGRHAGLVGSGHSEDGLSGSSGLVHNHVALPDLSRQPDSYGDLGHGTAPGTTDIKREEQEDEENVAADTAEDEKKDLKAPRTRSSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAAHPGLGEAHNPAGHL", "length": 642, "header": "tr|A0A3Q1LQN2-1|A0A3Q1LQN2_BOVIN Isoform 1 of Transcription factor E2-alpha OS=Bos taurus OX=9913 GN=TCF3 PE=4 SV=1 CANONICAL=A0A3Q1LQN2-1" }, "locus": { "chromosome": "7", "start_pos": 44012809, "end_pos": 43983983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071565.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071565.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057296.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057296.1" } ] } }, { "isoform_ac": "A0AAA9SVE4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVE4/entry", "sequence": { "sequence": "MNQSQRMAPVGTDKELSDLLDFSMMFPLPVANGKSRPASLAGTQFGSSGLEDRPSSGSWGTSEQDSSSFDPGRTYSDGAHFGESHSSLPSSTFLGPGLGGECLMCGTRAPRTSPHAHLVWEVGSVLVPSKGSERGAYAAFGRDAGVSSLTQVGFLPSELALSSPGPLSPSGIKGGSQYYSYSGHPRRRATDSSLDSQPKKVRKVPPGLPSSVYPPSSGDDYGRDPTTYPSAKTPSSSYPTPFYMADGSLHPSAELWSAPGQAGFGPMLGGGSSPLPLPAGGGSSVGGSGGFGSLHQHERMGYQLHGAEVNGGLPAASTFSGPAGTYSSISSHTPPVSGADSLLGSRGTTSSSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRPGAPGALSPSYDGGLHGLQSKVEDHLDEAIHVLRSHAVGTAGDVHGLLPGHGALTSGFAGPVMPLGGRHAGLVGSGHSEDGLSGSSGLVHNHVALPDLSRQPDSYGDLGHGTAPGTTDIKREEQEDEENVAADTAEDEKKDLKAPRTRSSTEEVLSLEEKDLRDRERRMANNARERVRVRDINEAFRELGRMCQLHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAAHPGLGEAHNPAGHL", "length": 667, "header": "tr|A0AAA9SVE4-1|A0A3Q1LQN2_BOVIN Computationally mapped isoform of Transcription factor E2-alpha OS=Bos taurus OX=9913 GN=TCF3 PE=4 SV=1 CANONICAL=A0A3Q1LQN2-1" }, "locus": { "chromosome": "7", "start_pos": 44012809, "end_pos": 43983983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090568.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090568.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087160.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087160.1" } ] } }, { "isoform_ac": "F1MVI6-1", "url": "https://www.uniprot.org/uniprotkb/F1MVI6/entry", "sequence": { "sequence": "MNQSQRMAPVGTDKELSDLLDFSMMFPLPVANGKSRPASLAGTQFGSSGARSSLPPDWSGLCWDYPPAGSASFWMIYREGLQLMSPWSCFSGLEDRPSSGSWGTSEQDSSSFDPGRTYSDGAHFGESHSSLPSSTFLGPGLGGKGSERGAYAAFGRDAGVSSLTQVGFLPSELALSSPGPLSPSGIKGGSQYYSYSGHPRRRATDSSLDSQPKKVRKVPPGLPSSVYPPSSGDDYGRDPTTYPSAKTPSSSYPTPFYMADGSLHPSAELWSAPGQAGFGPMLGGGSSPLPLPAGGGSSVGGSGGFGSLHQHERMGYQLHGAEVNGGLPAASTFSGPAGTYSSISSHTPPVSGADSLLGSRGTTSSSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRPGAPGALSPSYDGGLHGLQSKVEDHLDEAIHVLRSHAVGTAGDVHGLLPGHGALTSGFAGPVMPLGGRHAGLVGSGHSEDGLSGSSGLVHNHVALPDLSRQPDSYGDLGHGTAPGTTDIKREEQEDEENVAADTAEDEKKDLKAPRTRSSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAAHPGLGEAHNPAGHL", "length": 685, "header": "tr|F1MVI6-1|A0A3Q1LQN2_BOVIN Computationally mapped isoform of Transcription factor E2-alpha OS=Bos taurus OX=9913 GN=TCF3 PE=4 SV=3 CANONICAL=A0A3Q1LQN2-1" }, "locus": { "chromosome": "7", "start_pos": 44012809, "end_pos": 43983983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028599.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028599.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028599.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028599.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-525793", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-525793", "resource": "Reactome", "description": "Myogenesis" }, { "id": "R-BTA-8939236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939236", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in differentiation of HSCs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LLP5-1", "protein_name": "Transcription factor E2-alpha", "gene_name": "Tcf3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKGRPASLAGTQFAGSGLEDRTSSGSWGNSDQNSSSFDPSRTYSEGAHFSESHNSLPSSTFLGPGLGGKGSERSAYATFGRDTSVSALSQAGFLPGELGLSSPGPLSPSGVKSSSQYYPSYPSNPRRRAADSGLDTQPKKVRKVPPGLPSSVYPPSSGDSYSRDAVAYPSAKTPSSTYPSPFYVADGSLHPSAELWSTPSQAGFGPMLADGSSPLPLAPGSNSVGTGAFGGLQQQERMSYQLHGSEVNGTLAAVSSFSSAPGTYGGTSGHTPPVSGAENLMGTRGTAASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLPGTSQWPRAGAPSALSPGYDGGLHGLQSKMEDRLDEAIHVLRSHAVGPASDLHGLLPGHGALTTSFPGPMPLGGRHAGLVGGGHPEDGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSYGGLGRAGATVGASEIKREEKDDEENSSVADAEEEKKDLKAPRTRTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLSSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPPGHL", "length": 650 }, "evidence": [ { "id": "A0A3Q1LQN2", "url": "https://omabrowser.org/oma/group/A0A3Q1LQN2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P15806-1", "protein_name": "Transcription factor E2-alpha", "gene_name": "Tcf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKSRPASLGGTQFAGSGLEDRPSSGSWGSSDQNSSSFDPSRTYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGTLSQAGFLPGELSLSSPGPLSPSGIKSSSQYYPSFPSNPRRRAADGGLDTQPKKVRKVPPGLPSSVYPPSSGDSYSRDAAAYPSAKTPSSAYPSPFYVADGSLHPSAELWSTPSQVGFGPMLGDGSSPLPLAPGSSSVGSGTFGGLQQQDRMGYQLHGSEVNGSLPAVSSFSAAPGTYSGTSGHTPPVSGAAAESLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLPGTSQWPRAGAPSALSPNYDAGLHGLSKMEDRLDEAIHVLRSHAVGTASDLHGLLPGHGALTTSFTGPMSLGGRHAGLVGGSHPEEGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSYSGLGRAGTTAGASEIKREEKEDEEIASVADAEEDKKDLKVPRTRTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLSSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPAGHL", "length": 651 }, "evidence": [ { "id": "A0A3Q1LQN2", "url": "https://omabrowser.org/oma/group/A0A3Q1LQN2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15923-1", "protein_name": "Transcription factor E2-alpha", "gene_name": "TCF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNQPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSGDQSSSSFDPSRTFSEGTHFTESHSSLSSSTFLGPGLGGKSGERGAYASFGRDAGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQPKKVRKVPPGLPSSVYPPSSGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSPPGQAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGAEVNGGLPSASSFSSAPGATYGGVSSHTPPVSGADSLLGSRGTTAGSSGDALGKALASIYSPDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLDEAIHVLRSHAVGTAGDMHTLLPGHGALASGFTGPMSLGGRHAGLVGGSHPEDGLAGSTSLMHNHAALPSQPGTLPDLSRPPDSYSGLGRAGATAAASEIKREEKEDEENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM", "length": 654 }, "evidence": [ { "id": "A0A3Q1LQN2", "url": "https://omabrowser.org/oma/group/A0A3Q1LQN2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P21677-1", "protein_name": "Transcription factor E2-alpha", "gene_name": "Tcf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKGRPASLAGTQFAGSGLEDRPSSESWGNSEQNSSSFDPSRAYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGTLSQAGFLPGELGLSSPGPLSPSGVKSSSQYYTSFPSNPRRRAADGGLDTQPKKVRKVPPGLPSSVYPSSSGDNYSRDATAYPSAKTPSSAYPSPFYVADGSLHPSAELWSPPGQVGFGPMLGDGSAPLPLAPGSSSVSSGAFGGLQQQDRMGYQLHGSEVNGTLPAVSSFSAAPGTYSGTSGHTPPVSGADSLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLPGTSQWPRAGAPSALSPNYDAGLHGLSKMEDRLDEAIHVLRSHAVGTASELHGLLPGHSTLTTSFAGPMSLGGRHAGLVSGSHPEDGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSFSGLGRAGVTAGASEIKREEKEDEEVTSVADAEEDKKDLKVPRTRTSPDEDEDDLLPPEQKAEREKERRVANNARERLRVRDINEAFKELGRMCQLHLSTEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPAGHL", "length": 649 }, "evidence": [ { "id": "A0A3Q1LQN2", "url": "https://omabrowser.org/oma/group/A0A3Q1LQN2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 13, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MEERGSPDGDPARNLEQGPEGPETPIQVVLRVRPMSAAELRRGEQSVLHCSGTRTLQVSPPGGGPDVAFRFGAVLDGASTQDDVFRACGVRRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQGEGVPVPPSLAGIMQRTFTWLLDRVQHLDVPVTLHASYLEIYNEQIRDLLSLGAPRPLPVRWNKTRGFYVEQLRVVEFGSLGALMELLQMGLSRRRSSAHTLNQASSRSHALLTLYISHQTPQQMPPVDTGELPAGGKLCFVDLAGSEKVVATGSRGELMLEANSINRSLLALGHCISLLLDPQRKQSHIPFRDSKLTKLLADSLGGHGVTLMVACVSPSAQCLPETLSTLRYASRAQRVTTRPQAPRPPKAKLPQHLETELLQLQEENLHLRSQLGQMDPKASGLSGARAAWAQRNLYGMLQEFMLENERLRKEKKQLQSSRDLAHGEQRILAQQVRELERRLLSACYLQQPGPGPTPPCPCVMVPPLLCHAPPLLCPRCQLCPLCRAPLAHWACPRRELHLPQVFGSKAPGDWPLSARPPPWAPPCCPSSAKCSRERSRSEWTQTQVLAEMLTKEKVMPSAPPLPAGPVNASPVLRGGAAVPNLARRLEALRDQIGTSLRRGRSQPPPR", "length": 636, "header": "tr|A0A3Q1LX75-1|A0A3Q1LX75_BOVIN Isoform 1 of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIF12 PE=3 SV=2 CANONICAL=A0A3Q1LX75-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LX75-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75/entry", "sequence": { "sequence": "MEERGSPDGDPARNLEQGPEGPETPIQVVLRVRPMSAAELRRGEQSVLHCSGTRTLQVSPPGGGPDVAFRFGAVLDGASTQDDVFRACGVRRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQGEGVPVPPSLAGIMQRTFTWLLDRVQHLDVPVTLHASYLEIYNEQIRDLLSLGAPRPLPVRWNKTRGFYVEQLRVVEFGSLGALMELLQMGLSRRRSSAHTLNQASSRSHALLTLYISHQTPQQMPPVDTGELPAGGKLCFVDLAGSEKVVATGSRGELMLEANSINRSLLALGHCISLLLDPQRKQSHIPFRDSKLTKLLADSLGGHGVTLMVACVSPSAQCLPETLSTLRYASRAQRVTTRPQAPRPPKAKLPQHLETELLQLQEENLHLRSQLGQMDPKASGLSGARAAWAQRNLYGMLQEFMLENERLRKEKKQLQSSRDLAHGEQRILAQQVRELERRLLSACYLQQPGPGPTPPCPCVMVPPLLCHAPPLLCPRCQLCPLCRAPLAHWACPRRELHLPQVFGSKAPGDWPLSARPPPWAPPCCPSSAKCSRERSRSEWTQTQVLAEMLTKEKVMPSAPPLPAGPVNASPVLRGGAAVPNLARRLEALRDQIGTSLRRGRSQPPPR", "length": 636, "header": "tr|A0A3Q1LX75-1|A0A3Q1LX75_BOVIN Isoform 1 of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIF12 PE=3 SV=2 CANONICAL=A0A3Q1LX75-1" }, "locus": { "chromosome": "8", "start_pos": 103330489, "end_pos": 103323098, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084687.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084687.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060105.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060105.2" } ] } }, { "isoform_ac": "A0A3Q1MGB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGB8/entry", "sequence": { "sequence": "MYGCESWTIKKAECLRIDAFDLWRWRRLSRVPWTIYGKWFNVAVGSTCPWLKRFKEKMTMSTVVLKAGPTSKEISVTNTHRRKGVCESISGTYEKTSTDGKFLYHKAKWNITMESYVVHTNYDEYAIFLTKKLSRRHGPTITVKLYGREPQLRESLLEEFREVALGVGIPEDAIFTMPDRGECVPGEQDPVPTPVSRARRAVLTQEEEGSGAGQPVTNFSKKADSCQLDYSQGPCLGLFKRYFYNGTSMACETFLYGGCMGNGNNFLSEKECLQTCRTVEACNLPIVQGPCRSYIQLWAFDAVKGKCVRFSYGGCKGNGNKFYSEKECKEYCGIPGEADEELLRFSN", "length": 347, "header": "tr|A0A3Q1MGB8-1|A0A3Q1LX75_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIF12 PE=3 SV=2 CANONICAL=A0A3Q1LX75-1" }, "locus": { "chromosome": "8", "start_pos": 103311796, "end_pos": 103296387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070933.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070933.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069585.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069585.2" } ] } }, { "isoform_ac": "A0AAA9TKR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKR8/entry", "sequence": { "sequence": "MRSLSGLLLLLTACLVVNASSVPTLPDDIQVQENFDLSRIYGKWFNVAVGSTCPWLKRFKEKMTMSTVVLKAGPTSKEISVTNTHRRKGVCESISGTYEKTSTDGKFLYHKAKWNITMESYVVHTNYDEYAIFLTKKLSRRHGPTITVKLYGREPQLRESLLEEFREVALGVGIPEDAIFTMPDRGECVPGEQDPVPTPVSRARRAVLTQEEEGSGAGQPVTNFSKKADSCQLDYSQGPCLGLFKRYFYNGTSMACETFLYGGCMGNGNNFLSEKECLQTCRTVEACNLPIVQGPCRSYIQLWAFDAVKGKCVRFSYGGCKGNGNKFYSEKECKEYCGIPGEGRRPHNAGRAPILAFSATFGLATSLLK", "length": 369, "header": "tr|A0AAA9TKR8-1|A0A3Q1LX75_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIF12 PE=3 SV=1 CANONICAL=A0A3Q1LX75-1" }, "locus": { "chromosome": "8", "start_pos": 103308403, "end_pos": 103296972, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106726.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106726.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098996.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098996.1" } ] } }, { "isoform_ac": "E1BBY6-1", "url": "https://www.uniprot.org/uniprotkb/E1BBY6/entry", "sequence": { "sequence": "MPSSRGSSQPKDQTHIFYVSYIGRDPARNLEQGPEGPETPIQVVLRVRPMSAAELRRGEQSVLHCSGTRTLQVSPPGGGPDVAFRFGAVLDGASTQDDVFRACGVRRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQGEGVPVPPSLAGIMQRTFTWLLDRVQHLDVPVTLHASYLEIYNEQIRDLLSLGAPRPLPVRWNKTRGFYVEQLRVVEFGSLGALMELLQMGLSRRRSSAHTLNQASSRSHALLTLYISHQTPQQMPPVDTGELPAGGKLCFVDLAGSEKVVATGSRGELMLEANSINRSLLALGHCISLLLDPQRKQSHIPFRDSKLTKLLADSLGGHGVTLMVACVSPSAQCLPETLSTLRYASRAQRVTTRPQAPRPPKAKLPQHLETELLQLQEENLHLRSQLGQMDPKASGLSGARAAWAQRNLYGMLQEFMLENERLRKEKKQLQSSRDLAHGEQRILAQQVRELERRLLSACYLQQPGPGPTPPCPCVMVPPLLCHAPPLLCPRCQLCPLCRAPLAHWACPRRELHLPQVFGSKAPGDWPLSARPPPWAPPCCPSSAKCSRERSRSEWTQTQVLAEMLTKEKVMPSAPPLPAGPVNASPVLRGGAAVPNLARRLEALRDQIGTSLRRGRSQPPPR", "length": 651, "header": "tr|E1BBY6-1|E1BBY6_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIF12 PE=3 SV=4 CANONICAL=A0A3Q1LX75-1" }, "locus": { "chromosome": "8", "start_pos": 103338361, "end_pos": 103323098, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020826.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020826.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020826.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020826.6" } ] } }, { "isoform_ac": "F1MMK9-1", "url": "https://www.uniprot.org/uniprotkb/F1MMK9/entry", "sequence": { "sequence": "MLSTCGVGEDSREFLGRPAKPVSDSPDRGTRAMRSLSGLLLLLTACLVVNASSVPTLPDDIQVQENFDLSRIYGKWFNVAVGSTCPWLKRFKEKMTMSTVVLKAGPTSKEISVTNTHRRKGVCESISGTYEKTSTDGKFLYHKAKWNITMESYVVHTNYDEYAIFLTKKLSRRHGPTITVKLYGREPQLRESLLEEFREVALGVGIPEDAIFTMPDRGECVPGEQDPVPTPVSRARRAVLTQEEEGSGAGQPVTNFSKKADSCQLDYSQGPCLGLFKRYFYNGTSMACETFLYGGCMGNGNNFLSEKECLQTCRTVEACNLPIVQGPCRSYIQLWAFDAVKGKCVRFSYGGCKGNGNKFYSEKECKEYCGIPGEADEELLRFSN", "length": 384, "header": "tr|F1MMK9-1|A0A3Q1LX75_BOVIN Computationally mapped isoform of Kinesin-like protein OS=Bos taurus OX=9913 GN=KIF12 PE=3 SV=4 CANONICAL=A0A3Q1LX75-1" }, "locus": { "chromosome": "8", "start_pos": 103311744, "end_pos": 103296387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020817.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020817.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020817.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020817.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 483, "start_aa": "Thr", "end_pos": 483, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr483", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:510819", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510819", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "IgA binding", "id": "GO:0019862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019862", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LX75", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LX75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX75" }, { "id": "PS50067", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinesin motor", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 365, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 483 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 597, "end_pos": 599 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LUM8-1", "uniprot_ac": "A0A3Q1LUM8", "uniprot_id": "A0A3Q1LUM8_BOVIN", "mass": { "chemical_mass": 196912.0, "monoisotopic_mass": 196912.0 }, "refseq": { "ac": "XP_024849702", "name": "chromodomain-helicase-DNA-binding protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849702" }, "gene_names": [ { "name": "CHD1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LUM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ] }, { "name": "CHD1", "type": "synonym", "evidence": [ { "id": "XP_024849702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849702" } ] } ], "protein_names": [ { "name": "Chromodomain helicase DNA binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LUM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8/entry#names_and_taxonomy" } ] }, { "name": "chromodomain-helicase-DNA-binding protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_024849702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849702" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHD1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8", "locus": { "chromosome": "7", "start_pos": 98079213, "end_pos": 98151747, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020860", "url": "https://www.ensembl.org/id/ENSBTAG00000020860" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020860", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020860", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18666", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18666", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505123", "url": "https://www.ncbi.nlm.nih.gov/gene/505123", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505123", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505123", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVQIRDD", "url": "https://omabrowser.org/oma/group/WVQIRDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LUM8", "url": "https://www.orthodb.org/?gene=A0A3Q1LUM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAR5", "url": "https://www.orthodb.org/?gene=A0A3Q1MAR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MGF2", "url": "https://www.orthodb.org/?gene=F1MGF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45623:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45623:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024849702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024849702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAR5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MGF2", "url": "https://www.uniprot.org/uniprotkb/F1MGF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MGF2-1", "url": "https://www.uniprot.org/uniprotkb/F1MGF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDNSRDNKVQAKPPKVDGAEFWKSSPSILAVQRSAMLKKQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEERDKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKIIGQKKRQIDSSEEEDDDEEEYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEAGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYIIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSDKSDEDDDKLSESKSESKERSKKSSVLDAPVHITAGGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPERGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNNDQNSSLNTQVIRNPDVERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLEGSLKDRTHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1711, "header": "tr|A0A3Q1LUM8-1|A0A3Q1LUM8_BOVIN Isoform 1 of Chromodomain helicase DNA binding protein 1 OS=Bos taurus OX=9913 GN=CHD1 PE=4 SV=2 CANONICAL=A0A3Q1LUM8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8/entry", "sequence": { "sequence": "MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDNSRDNKVQAKPPKVDGAEFWKSSPSILAVQRSAMLKKQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEERDKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKIIGQKKRQIDSSEEEDDDEEEYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEAGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYIIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSDKSDEDDDKLSESKSESKERSKKSSVLDAPVHITAGGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPERGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNNDQNSSLNTQVIRNPDVERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLEGSLKDRTHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1711, "header": "tr|A0A3Q1LUM8-1|A0A3Q1LUM8_BOVIN Isoform 1 of Chromodomain helicase DNA binding protein 1 OS=Bos taurus OX=9913 GN=CHD1 PE=4 SV=2 CANONICAL=A0A3Q1LUM8-1" }, "locus": { "chromosome": "7", "start_pos": 98151662, "end_pos": 98080674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078946.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078946.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064253.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064253.2" } ] } }, { "isoform_ac": "A0A3Q1MAR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR5/entry", "sequence": { "sequence": "MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDNSRDNKVQAKPPKVDGAEFWKSSPSILAVQRSAMLKKQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEERDKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKIIGQKKRQIDSSEEEDDDEEEYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEAGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYIIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGALSESKSESKERSKKSSVLDAPVHITAGGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPERGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNNDQNSSLNTQVIRNPDVERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLEGSLKDRTHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1668, "header": "tr|A0A3Q1MAR5-1|A0A3Q1LUM8_BOVIN Computationally mapped isoform of Chromodomain helicase DNA binding protein 1 OS=Bos taurus OX=9913 GN=CHD1 PE=4 SV=2 CANONICAL=A0A3Q1LUM8-1" }, "locus": { "chromosome": "7", "start_pos": 98151662, "end_pos": 98080674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067483.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067483.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067721.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067721.2" } ] } }, { "isoform_ac": "F1MGF2-1", "url": "https://www.uniprot.org/uniprotkb/F1MGF2/entry", "sequence": { "sequence": "MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDNSRDNKVQAKPPKVDGAEFWKSSPSILAVQRSAMLKKQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEERDKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKIIGQKKRQIDSSEEEDDDEEEYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIDKIQCKIYLVYLTAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEAGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGDIKMKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYIIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSDKSDEDDDKDEITSVKHPNKKIKTERDSEEKTEPDVCIKKEPEEKREAKEKENKRELKREIKEKEDKKDIKEKDFKEKRENKVKEAIQKEKDIKEEKLSESKSESKERSKKSSVLDAPVHITAGGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPERGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNNDQNSSLNTQVIRNPDVERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLEGSLKDRTHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1810, "header": "tr|F1MGF2-1|A0A3Q1LUM8_BOVIN Computationally mapped isoform of Chromodomain helicase DNA binding protein 1 OS=Bos taurus OX=9913 GN=CHD1 PE=4 SV=3 CANONICAL=A0A3Q1LUM8-1" }, "locus": { "chromosome": "7", "start_pos": 98151662, "end_pos": 98080674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034967.5", "url": "https://www.ensembl.org/id/ENSBTAT00000034967.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034848.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034848.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505123", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505123", "resource": "KEGG Pathway" }, { "id": "R-BTA-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K5T4-1", "protein_name": "Chromodomain helicase DNA binding protein 1", "gene_name": "Chd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAVGKVGRTVLISSPHCQSEDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSDSGSQSESESDTSRENKVQAKPPKVDGAEFWKSNPSILAVQRSAMLRKQTQQPQQQRPASSNSGSEEDSSSSEDSDASSSDVKRKKHNDEDWQMSGSGSPSQSGSDSESEDERDKSSCDGTESDYEPKNKVKSRKPQNRSKSKSGKKILGQKKRQIDSSEDEDDEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQTEDEEFETIERFMDCRVGRKGATGATTTIYAIEADGDPNAGFEKSKEPGDVQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGLPDYYCKWQGLPYSECSWEDGALISKKFQTCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRRQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEDIIPEEQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCVKALKDSSSGTERAGGRLGKVKGPTFRISGVQVNAKLVIAHEDELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKTRAKKNKAMKSIKVKEEIKSDSSPLPSERSEEEDDNVNDSKPESKDRSKKSVVSDAPVHITASGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSNVPTTHVIRNPDMERLKENTNHDDSSRDGYSSDRHLSQCHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHREWDHYRQDSRYYSDREKHRKLDDHRSREHRPSVEGSLKDRCHSDHRSHSDHRMHSDHRSSTEHTHHKSSRDYRYLSDWQLDHRAASSGPRSPLDQRSPYGSRSPFEHSAEHRSTPEHTWSSRKT", "length": 1711 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YMT9-1", "protein_name": "Chromodomain helicase DNA binding protein 1Z", "gene_name": "CHD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNGHSDEESVRNSSGESSRSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSESGSESGSQSESESDTSREKKQVQAKPPKADGSEFWKSSPSILAVQRSAVLKKQQQQQKAASSDSGSEEDSSSSEDSADDSSSETKKKKHKDEDWQMSGSGSVSGTGSDSESEEDGDKSSCEESESDYEPKNKVKSRKPPSRIKPKSGKKSTGQKKRQLDSSEEEEDDDEDYDKRGSRRQATVNVSYKEAEETKTDSDDLLEVCGEDVPQTEEDEFETIEKFMDSRIGRKGATGASTTIYAVEADGDPNAGFEKSKELGEIQYLIKWKGWSHIHNTWETEETLKQQNVKGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQARIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHESLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETRENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSRNWEEIIPESQRRRIEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSITERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAVARDAELVDKSETDLRRLGELVHNGCIKALKDNSSGQERAGGRLGKVKGPTFRISGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPCHTKAAHFDIDWGKEDDSNLLVGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRNKKNKMKASKIKEEIKSDSSPQPSEKSDEDDEEEDNKDEIVSVKHLHKKIKTEKENEEKPEPDIGIKKEAEEKRETKEKENKRELKREKKEKEDKKELKEKDNKEKRENKVKESTQKEKEVKEEKVNEIKSENKEKSKKIPLLDTPVHITATSEPVPISEESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHNDQNISSNVNTHVIRNPDVERLKETTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDAYKKSDSRKRPYSAFSNGKDHRDWDHYKQDSRYYSDSKHRKLDDHRSRDHRSNLEGNLKDSRGHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGPRSPLDQRSPYGSRSPLGHRSPFEHSSDHKSTPEHTWSSRKT", "length": 1808 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F4IV99-1", "protein_name": "Protein CHROMATIN REMODELING 5", "gene_name": "CHR5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAFFRNYSNDTVSHNVLDENEERQNAATFQSSPLNEDVDGTYSERGFDMNMDVQYQSDPEPGCSIRQPNETAVDNVADPVDSHYQSSTKRLGVTGRWGSTFWKDCQPMGQREGSDPAKDSQSGYKEAYHSEDNHSNDRSEKLDSENENDNENEEEDNEMNKHQSGQADVPADEMLSDEYYEQDEDNQSDHVHYKGYSNPTNSRSLPKAGSAVHSNSRTSRAIHKNIHYSDSNHDHNGDADMDYEEEEDEDDPEDADFEPYDAADDGGASKKHGQGWDVSDEDPESDEEIDLSDYEDDYGTKKPKVRQQSKGFRKSSAGLERKSFHVSSRQKRKTSYQDDDSEEDSENDNDEGFRSLARRGTTLRQNNGRSTNTIGQSSEVRSSTRSVRKVSYVESEDSEDIDDGKNRKNQKDDIEEEDADVIEKVLWHQLKGMGEDVQTNNKSTVPVLVSQLFDTEPDWNEMEFLIKWKGQSHLHCQWKTLSDLQNLSGFKKVLNYTKKVTEEIRYRTALSREEIEVNDVSKEMDLDIIKQNSQVERIIADRISKDGLGDVVPEYLVKWQGLSYAEATWEKDVDIAFAQVAIDEYKAREVSIAVQGKMVEQQRTKGKASLRKLDEQPEWLIGGTLRDYQLEGLNFLVNSWLNDTNVILADEMGLGKTVQSVSMLGFLQNTQQIPGPFLVVVPLSTLANWAKEFRKWLPGMNIIVYVGTRASREVCQQYEFYNEKKVGRPIKFNALLTTYEVVLKDKAVLSKIKWIYLMVDEAHRLKNSEAQLYTALLEFSTKNKLLITGTPLQNSVEELWALLHFLDPGKFKNKDEFVENYKNLSSFNESELANLHLELRPHILRRVIKDVEKSLPPKIERILRVEMSPLQKQYYKWILERNFHDLNKGVRGNQVSLLNIVVELKKCCNHPFLFESADHGYGGDINDNSKLDKIILSSGKLVILDKLLVRLRETKHRVLIFSQMVRMLDILAEYLSLRGFQFQRLDGSTKAELRQQAMDHFNAPASDDFCFLLSTRAGGLGINLATADTVVIFDSDWNPQNDLQAMSRAHRIGQQEVVNIYRFVTSKSVEEEILERAKRKMVLDHLVIQKLNAEGRLEKRETKKGSNFDKNELSAILRFGAEELFKEDKNDEESKKRLLSMDIDEILERAEQVEEKHTDETEHELLGAFKVANFCNAEDDGSFWSRWIKPDSVVTAEEALAPRAARNTKSYVDPSHPDRTSKRKKKGSEPPEHTERSQKRRKTEYFVPSTPLLEGTSAQVRGWSYGNLPKRDAQRFYRTVMKFGNHNQMACIAEEVGGVVEAAPEEAQVELFDALIDGCKESVETGNFEPKGPVLDFFGVPVKANELLKRVQGLQLLSKRISRYNDPISQFRVLSYLKPSNWSKGCGWNQIDDARLLLGILYHGFGNWEKIRLDESLGLTKKIAPVELQHHETFLPRAPNLKERATALLEMELAAAGGKNTNAKASRKNSKKVKDNLINQFKAPARDRRGKSGPANVSLLSTKDGPRKTQKAEPLVKEEGEMSDDGEVYEQFKEQKWMEWCEDVLADEIKTLGRLQRLQTTSADLPKEKVLFKIRRYLEILGRRIDAIVLEHEEDLYKQDRMTMRLWNYVSTFSNLSGDRLNQIYSKLKQEKEEEEGVGPSHLNGSRNFQRQQKFKTAGNSQGSQQVHKGIDTAKFEAWKRRRRTENDVQTERPTITNSNSLGILGPGPLDRSHRARQTGFPPR", "length": 1724 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3HNU4-1", "protein_name": "Chromodomain-helicase-DNA-binding protein 1", "gene_name": "Chd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGHSDEESVRNGSGESSQSEDDSGSASGSGSGSSSGSSSGGSSSQSGSSDSDSGSDSGSQSESESDTSRENKVQAKPPKVDGAEFWKSNPSILAVQRSAILKKQPQQPQQVHAASSNSGSEEDSSSSEDSDDSSSEVKRKKHNDEDWQMSGSGSPSQSGSDSESEEERDKSSCDETESDYEPKNKVKSRKPQSRCKSKNGKKILGQKKRQIDSSEDEDDEDYDNDKRSSRRQATVNVSYKEDEDMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRVGRRGATGATTTIYAVEADGDPNAGFEKNKEPGDIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGLPDYYCKWQGLPYSECSWEDGALISKKFQSCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHLQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGNEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCVKALKDSSSGTDRTGGRLGKVKGPTFRISGVQVNAKLVIAHEDELIPLHKSIPSDPEERKRYTIPCHTKAAHFDIDWGREDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEAQRLSGAGGSKRRKTRTKKNKTTKSIKIKEEIKSDSSPLPSEKSDEDDDKLNESKPESKDRSKKSVVSDAPVHITASGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSSITTHVIRNPDMERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDCYKKSDSRKRPYSSLSNGKDHREWDHYKQDSRYYSDREKHRKLDDHRSREHRSSLEGSLKDRCHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRFLSDWQMDHRAASTGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1710 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O14646-1", "protein_name": "ATP-dependent chromatin remodeler CHD1", "gene_name": "CHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEALSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRERSKKSSVSDAPVHITASGEPVPISEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSNLNPHVIRNPDVERLKENTNHDDSSRDSYSSDRHLTQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLEGSLKDRSHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLDQRSPYGSRSPFEHSVEHKSTPEHTWSSRKT", "length": 1710 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32657-1", "protein_name": "ATP-dependent chromatin remodeler CHD1", "gene_name": "CHD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAAKDISTEVLQNPELYGLRRSHRAAAHQQNYFNDSDDEDDEDNIKQSRRKRMTTIEDDEDEFEDEEGEEDSGEDEDEEDFEEDDDYYGSPIKQNRSKPKSRTKSKSKSKPKSQSEKQSTVKIPTRFSNRQNKTVNYNIDYSDDDLLESEDDYGSEEALSEENVHEASANPQPEDFHGIDIVINHRLKTSLEEGKVLEKTVPDLNNCKENYEFLIKWTDESHLHNTWETYESIGQVRGLKRLDNYCKQFIIEDQQVRLDPYVTAEDIEIMDMERERRLDEFEEFHVPERIIDSQRASLEDGTSQLQYLVKWRRLNYDEATWENATDIVKLAPEQVKHFQNRENSKILPQYSSNYTSQRPRFEKLSVQPPFIKGGELRDFQLTGINWMAFLWSKGDNGILADEMGLGKTVQTVAFISWLIFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDTIREYEFYTNPRAKGKKTMKFNVLLTTYEYILKDRAELGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFTIDQEIDFENQDEEQEEYIHDLHRRIQPFILRRLKKDVEKSLPSKTERILRVELSDVQTEYYKNILTKNYSALTAGAKGGHFSLLNIMNELKKASNHPYLFDNAEERVLQKFGDGKMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLVSKDTVEEEVLERARKKMILEYAIISLGVTDGNKYTKKNEPNAGELSAILKFGAGNMFTATDNQKKLEDLNLDDVLNHAEDHVTTPDLGESHLGGEEFLKQFEVTDYKADIDWDDIIPEEELKKLQDEEQKRKDEEYVKEQLEMMNRRDNALKKIKNSVNGDGTAANSDSDDDSTSRSSRRRARANDMDSIGESEVRALYKAILKFGNLKEILDELIADGTLPVKSFEKYGETYDEMMEAAKDCVHEEEKNRKEILEKLEKHATAYRAKLKSGEIKAENQPKDNPLTRLSLKKREKKAVLFNFKGVKSLNAESLLSRVEDLKYLKNLINSNYKDDPLKFSLGNNTPKPVQNWSSNWTKEEDEKLLIGVFKYGYGSWTQIRDDPFLGITDKIFLNEVHNPVAKKSASSSDTTPTPSKKGKGITGSSKKVPGAIHLGRRVDYLLSFLRGGLNTKSPSADIGSKKLPTGPSKKRQRKPANHSKSMTPEITSSEPANGPPSKRMKALPKGPAALINNTRLSPNSPTPPLKSKVSRDNGTRQSSNPSSGSAHEKEYDSMDEEDCRHTMSAIRTSLKRLRRGGKSLDRKEWAKILKTELTTIGNHIESQKGSSRKASPEKYRKHLWSYSANFWPADVKSTKLMAMYDKITESQKK", "length": 1468 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40201-1", "protein_name": "ATP-dependent chromatin remodeler CHD1", "gene_name": "Chd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGHSDEESVRNGSGESSQSGDDCGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSDSGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAMLRKQPQQAQQQRPASSNSGSEEDSSSSEDSDDSSSGAKRKKHNDEDWQMSGSGSPSQSGSDSESEEERDKSSCDGTESDYEPKNKVRSRKPQNRSKSKNGKKILGQKKRQIDSSEDEDDEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEDEEFETIERVMDCRVGRKGATGATTTIYAVEADGDPNAGFERNKEPGDIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGLPDYYCKWQGLPYSECSWEDGALISKKFQTCIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLSVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEEQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCVKALKDSSSGTERAGGRLGKVKGPTFRISGVQVNAKLVIAHEDELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKREAQRLCGAGGSKRRKTRAKKSKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLNDSKPESKDRSKKSVVSDAPVHITASGEPVPIAEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYSNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSNVATTHVIRNPDMERLKENTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHREWDHYRQDSRYYSDREKHRKLDDHRSREHRPSLEGGLKDRCHSDHRSHSDHRMHSDHRSSSEHTHHKSSRDYRYLSDWQLDHRAASSGPRSPLDQRSPYGSRSPFEHSAEHRSTPEHTWSSRKT", "length": 1711 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KU24-1", "protein_name": "ATP-dependent chromatin remodeler Chd1", "gene_name": "Chd1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQALNESANSIGSDEQDDTREEANGTDHSGSGSGSGSSGSDSDSDSSSGNSSDGRSSPEPEDKSLSVAGFPPTAAAAQADSKTNGFTDDQEDSSSDGSSGSDSDSDAEGPSDQRNQSINNANTSSSLPKPEQNEEEDNETEAGQQQPASDASADESSDSSANVSPTSSSSSSEEEEEDYRPKRTRQARKPPTAAEKSKKAPAPKNKKKTWDSDESDESEDSDDEVSTAQKRKPAATTSRSKLAQQQQRRRVKPFSSEDSDDDDASKRCATRRKGAAVSYKEASEDEATDSEDLLEFEYDESQAATTAATAEEEEKCETIERILAQRAGKRGCTGNQTTIYAIEENGFDPHAGFDEKQTPDAETEAQFLIKWKGWSYIHNTWESEATLRDMKAKGMKKLDNFIKKEKEQAYWRRYAGPEDIDYFECQLELQHELLKSYNNVDRIIAKGSKPDDGTEEYLCKWQSLPYAESTWEDAALVLRKWQRCAEQFNDRESSKCTPSRHCRVIKYRPKFSRIKNQPEFLSSGLTLRDYQMDGLNWLLHSWCKENSVILADEMGLGKTIQTICFLYSLFKIHHLYGPFLCVVPLSTMTAWQREFDLWAPDMNVVTYLGDIKSRELIQQYEWQFESSKRLKFNCILTTYEIVLKDKQFLGTLQWAALLVDEAHRLKNDDSLLYKSLKEFDTNHRLLITGTPLQNSLKELWALLHFIMPDKFDTWENFEVQHGNAEDKGYTRLHQQLEPYILRRVKKDVEKSLPAKVEQILRVEMTSLQKQYYKWILTKNFDALRKGKRGSTSTFLNIVIELKKCCNHAALIRPSEFELMGLQQDEALQTLLKGSGKLVLLDKLLCRLKETGHRVLIFSQMVRMLDVLADYLQKRHFPFQRLDGSIKGEMRRQALDHFNAEGSQDFCFLLSTRAGGLGINLATADTVIIFDSDWNPQNDLQAQARAHRIGQKNQVNIYRLVTARSVEEQIVERAKQKMVLDHLVIQRMDTTGRTVLDKSGNGHSSNSNPFNKDDLSAILKFGAEELFKDEQEHDDDLVCDIDEILRRAETRNEDPEMPADDLLSAFKVASIAAFEEEPSDSVSKQDQNAAGEEDDSKDWDDIIPEGFRKAIDDQERAKEMEDLYLPPRRKTAANQNEGKRGAGKGGKGKQQADDSGGDSDYELGSDGSGDDGRPRKRGRPTMKEKITGFTDAELRRFIRSYKKFPAPLHRMEAIACDAELQEKPLAELKRLGEMLHDRCVQFLHEHKEEESKTAATDETPGAKQRRARATFSVKLGGVSFNAKKLLACEQELQPLNEIMPSMPEERQQWSFNIKTRAPVFDVDWGIEEDTKLLCGIYQYGIGSWEQMKLDPTLKLTDKILLNDTRKPQAKQLQTRAEYLLKIIKKNVELTKGGQRRQRRPRASRANDAKAASQSASSTIDAKPHDGEDAAGDARTVAESSNSQVDPSTASPHNAPATEQHGDPAKKAKKSKARSKKTSASDNNGNKPMHFTANNEPRALEVLGDLDPSIFNECKEKMRPVKKALKALDQPDVSLSDQDQLQHTRDCLLQIGKQIDVCLNPYAETEKKEWRSNLWYFVSKFTELDAKRLFKIYKHALKQKAGGDGEAKGKDKGSSGSPAKSKPNGVTTEEKEKERDRSGGKKKKKDKDKERSGQARYPETGIPTSGRYADPPLKRKRDENDADASSGLAGAPGGGIGDNLKSMSFKRLNMDRHEDRKKHHRGPDYYGGSGPPMGSGSYEGGSNSRRQGPTSPSTPRTGRGGYDPPPAPSGYTPEMERWQSRDRYSQDYKRDRYDGYGRSGGGQGSYHRERDRRPEKRRYPSGLPPHPYSSHYLPPNYYGLPNGAVPGLPPPSSVYRSDPRGYPVMPRDYPADYRRSDYERRTQT", "length": 1883 }, "evidence": [ { "id": "A0A3Q1LUM8", "url": "https://omabrowser.org/oma/group/A0A3Q1LUM8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "nuclear chromosome", "id": "GO:0000228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000228", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "host-mediated activation of viral transcription", "id": "GO:0043923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043923", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" }, { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUM8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1082, "end_pos": 1084, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1515, "end_pos": 1517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", 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"evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": 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{ "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": 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"activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] } ] }, { "uniprot_ac": "Q0V8B7", "gene_name": "MCM5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] } ] }, { "uniprot_ac": "Q0V8H6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP + n phosphate + unwound RNA.", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] } ] }, { "uniprot_ac": "Q0VCX2", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": 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{ "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] } ] }, { "uniprot_ac": "Q29S22", "gene_name": "DDX47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] } ] }, { "uniprot_ac": "Q2HJF8", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2HJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF8" } ] } ] }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LUV2-1", "uniprot_ac": "A0A3Q1LUV2", "uniprot_id": "A0A3Q1LUV2_BOVIN", "mass": { "chemical_mass": 79359.0, "monoisotopic_mass": 79359.0 }, "refseq": {}, "gene_names": [ { "name": "PGM3", "type": "recommended", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ] } ], "protein_names": [ { "name": "Phosphoacetylglucosamine mutase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2/entry#names_and_taxonomy" } ] }, { "name": "5.4.2.3", "type": "synonym", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2/entry#names_and_taxonomy" } ] }, { "name": "Acetylglucosamine phosphomutase", "type": "synonym", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2/entry#names_and_taxonomy" } ] }, { "name": "N-acetylglucosamine-phosphate mutase", "type": "synonym", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2/entry#names_and_taxonomy" } ] }, { "name": "Phosphoglucomutase-3", "type": "synonym", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.", "evidence": [ { "database": "UniProtKB", "id": "F1MS56", "url": "https://www.uniprot.org/uniprotkb/F1MS56#function" }, { "database": "UniProtKB", "id": "PIRNR016408", "url": "https://www.uniprot.org/uniprotkb/PIRNR016408#function" }, { "database": "UniProtKB", "id": "ARBA00059527", "url": "https://www.uniprot.org/uniprotkb/ARBA00059527#function" }, { "database": "UniProtKB", "id": "A0A3Q1LP83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP83#function" }, { "database": "UniProtKB", "id": "ARBA00060228", "url": "https://www.uniprot.org/uniprotkb/ARBA00060228#function" }, { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2#function" }, { "database": "UniProtKB", "id": "A0AAA9S6Z2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6Z2#function" }, { "database": "UniProtKB", "id": "A0AAA9T0G6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0G6#function" }, { "database": "UniProtKB", "id": "A0AAA9TAN4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAN4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PGM3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2", "locus": { "chromosome": "9", "start_pos": 23087452, "end_pos": 23117094, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000679", "url": "https://www.ensembl.org/id/ENSBTAG00000000679" } ] } } ], "crossref": [ { "id": "A0A3Q1LUV2", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LUV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000679", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000679", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LP83", "url": "https://www.orthodb.org/?gene=A0A3Q1LP83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MS56", "url": "https://www.orthodb.org/?gene=F1MS56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45955:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45955:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21404", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21404", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21405", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21405", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-446210", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "23804", "url": "https://www.rhea-db.org/rhea/23804", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LP83", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6Z2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ04", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ04-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0G6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0G6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAN4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MS56", "url": "https://www.uniprot.org/uniprotkb/F1MS56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MS56-1", "url": "https://www.uniprot.org/uniprotkb/F1MS56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTKPDTYTLPLYFLTPRSSIHISQNVSLKFRFSFPPPPPVPIWVQVSGFSTSVRSYPVADGWQAPPADTASLNSGKGEGPSFQIPPRCAAWAAVSAATREVRSIGEARLRIPGLRGLLGPPRSTPVSDPAASAPRTPARWAFRLSQEPPQTGTANVSPDDLDPLGLCPQGFQLNERGRPDMDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF", "length": 723, "header": "tr|A0A3Q1LUV2-1|A0A3Q1LUV2_BOVIN Isoform 1 of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=1 CANONICAL=A0A3Q1LUV2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP83-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP83/entry", "sequence": { "sequence": "MDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF", "length": 501, "header": "tr|A0A3Q1LP83-1|A0A3Q1LP83_BOVIN Computationally mapped isoform of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=2 CANONICAL=A0A3Q1LUV2-1" }, "locus": { "chromosome": "9", "start_pos": 23114210, "end_pos": 23089742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086526.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086526.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056702.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056702.2" } ] } }, { "isoform_ac": "A0A3Q1LUV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2/entry", "sequence": { "sequence": "MGTKPDTYTLPLYFLTPRSSIHISQNVSLKFRFSFPPPPPVPIWVQVSGFSTSVRSYPVADGWQAPPADTASLNSGKGEGPSFQIPPRCAAWAAVSAATREVRSIGEARLRIPGLRGLLGPPRSTPVSDPAASAPRTPARWAFRLSQEPPQTGTANVSPDDLDPLGLCPQGFQLNERGRPDMDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF", "length": 723, "header": "tr|A0A3Q1LUV2-1|A0A3Q1LUV2_BOVIN Isoform 1 of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=1 CANONICAL=A0A3Q1LUV2-1" }, "locus": { "chromosome": "9", "start_pos": 23116895, "end_pos": 23089742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071281.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071281.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064340.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064340.2" } ] } }, { "isoform_ac": "A0AAA9S6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6Z2/entry", "sequence": { "sequence": "MNCWGQPDFCPEVDKTDMDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF", "length": 559, "header": "tr|A0AAA9S6Z2-1|A0A3Q1LUV2_BOVIN Computationally mapped isoform of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=1 CANONICAL=A0A3Q1LUV2-1" }, "locus": { "chromosome": "9", "start_pos": 23116429, "end_pos": 23089742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101157.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101157.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077940.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077940.1" } ] } }, { "isoform_ac": "A0AAA9SJ04-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ04/entry", "sequence": { "sequence": "MDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF", "length": 396, "header": "tr|A0AAA9SJ04-1|A0A3Q1LUV2_BOVIN Computationally mapped isoform of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=1 CANONICAL=A0A3Q1LUV2-1" }, "locus": { "chromosome": "9", "start_pos": 23114210, "end_pos": 23089742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099558.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099558.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086223.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086223.1" } ] } }, { "isoform_ac": "A0AAA9T0G6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0G6/entry", "sequence": { "sequence": "MGRFGGEEEGELTRNCWGQPDFCPEVDKTDMDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF", "length": 572, "header": "tr|A0AAA9T0G6-1|A0A3Q1LUV2_BOVIN Computationally mapped isoform of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=1 CANONICAL=A0A3Q1LUV2-1" }, "locus": { "chromosome": "9", "start_pos": 23115497, "end_pos": 23089742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097711.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097711.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090007.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090007.1" } ] } }, { "isoform_ac": "A0AAA9TAN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAN4/entry", "sequence": { "sequence": "MDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRASSPCWGRRWSRGRGSLSVLRTGW", "length": 564, "header": "tr|A0AAA9TAN4-1|A0A3Q1LUV2_BOVIN Computationally mapped isoform of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=1 CANONICAL=A0A3Q1LUV2-1" }, "locus": { "chromosome": "9", "start_pos": 23114210, "end_pos": 23088456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105204.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105204.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093069.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093069.1" } ] } }, { "isoform_ac": "F1MS56-1", "url": "https://www.uniprot.org/uniprotkb/F1MS56/entry", "sequence": { "sequence": "MDLDAVTKQSVLHAKPDGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAASWEEHATCLANAEEQHLPRVLVDISEKAAVDLHQDAFVVIGRDTRPSSERLSQSVIDGVTVLGGQFYDYGLLTTPQLHYMVFCRNSNGQYGKATVEGYYQKLSSAFVELTKQAFCRGDDHRTLKVDCANGIGALKLAEMKHYFSPGLSVQLFNDGTKGKLNHLCGADFVKSHQKPPQGIEMRANERCCSFDGDADRIVYYYHDADGQFHLIDGDKIATLISSFLKELLLEIGDGLSLGVVQTAYANGSSTRYLEEVMKVLFSKAAETKIKQLAKESEDEKRKAAKMLENIIDLFNQTIGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVKVADRQVISTTDAERQVVKPPGLQEAINDLVKKYRLSRAFVRPSGTEDIVRVYAEADSQENTDSLAYEVSLAVFQLAGGIGERPQRGF", "length": 509, "header": "tr|F1MS56-1|A0A3Q1LUV2_BOVIN Computationally mapped isoform of Phosphoacetylglucosamine mutase OS=Bos taurus OX=9913 GN=PGM3 PE=3 SV=2 CANONICAL=A0A3Q1LUV2-1" }, "locus": { "chromosome": "9", "start_pos": 23114210, "end_pos": 23089742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000902.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000902.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000902.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000902.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-446210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446210", "resource": "Reactome", "description": "Synthesis of UDP-N-acetyl-glucosamine" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" }, { "name": "phosphoacetylglucosamine mutase activity", "id": "GO:0004610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004610", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine biosynthetic process", "id": "GO:0006048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006048", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" }, { "name": "cell wall organization", "id": "GO:0071555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071555", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" }, { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" }, { "name": "amino sugar biosynthetic process", "id": "GO:0046349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046349", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LUV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23804", "name": "", "equation": "N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LUV2-1" ], "evidence": [ { "id": "23804", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23804" } ] }, { "id": "R-BTA-446185", "name": "Isomerization of GlcNAc6P to GlcNAc1P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-449703" ], "output_participant_list": [ "R-ALL-532204" ], "enzyme_list": [ "A0A3Q1LUV2-1" ], "evidence": [ { "id": "R-BTA-446185", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-446185" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-449703", "participant_name": "AcGlcN6P [cytosol]", "crossref": [ { "id": "57513", "database": "ChEBI", "url": "" }, { "id": "ZINC000004097101", "database": "ZINC", "url": "" }, { "id": "ZINC000004097100", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-532204", "participant_name": "AcGlcN1P [cytosol]", "crossref": [ { "id": "ZINC000004096361", "database": "ZINC", "url": "" }, { "id": "57776", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LUV2", "gene_name": "PGM3", "activity": [ { "ec_number": "5.4.2.3", "activity": "N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ] }, { "ec_number": "5.4.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" }, { "id": "PF00408", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00408" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-D-phosphohexomutase C-terminal", "eco_id": "ECO_0000259", "start_pos": 652, "end_pos": 704, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" }, { "id": "PF02878", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-D-phosphohexomutase alpha/beta/alpha", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 271, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LUV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV2" }, { "id": "PF21405", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21405" }, { "id": "PF21404", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21404" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphoacetylglucosamine mutase AMG1", "eco_id": "ECO_0000259", "start_pos": 359, "end_pos": 464, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "PIRSR016408-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR016408-3" } ], "binding_site_uniprot": 276, "amino_acid": "Ala", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 276, "end_pos": 276, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR016408-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR016408-3" } ], "binding_site_uniprot": 278, "amino_acid": "Ala", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 278, "end_pos": 278, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR016408-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR016408-3" } ], "binding_site_uniprot": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LSG5-1", "uniprot_ac": "A0A3Q1LSG5", "uniprot_id": "A0A3Q1LSG5_BOVIN", "mass": { "chemical_mass": 56939.0, "monoisotopic_mass": 56939.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100125266", "type": "recommended", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ] } ], "protein_names": [ { "name": "Alkaline phosphatase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100125266", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5", "locus": {} } ], "crossref": [ { "id": "A0A3Q1LSG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LSG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004519", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000012363", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012363", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000051665", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051665", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "280993", "url": "https://www.ncbi.nlm.nih.gov/gene/280993", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:280993", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:280993", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEGLAYH", "url": "https://omabrowser.org/oma/group/HEGLAYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "NDCAGAR", "url": "https://omabrowser.org/oma/group/NDCAGAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N2M5", "url": "https://www.orthodb.org/?gene=F1N2M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N6T5", "url": "https://www.orthodb.org/?gene=F1N6T5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00245", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00245", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "15017", "url": "https://www.rhea-db.org/rhea/15017", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LSG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG33", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG33-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2M5", "url": "https://www.uniprot.org/uniprotkb/F1N2M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2M5-1", "url": "https://www.uniprot.org/uniprotkb/F1N2M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6T5", "url": "https://www.uniprot.org/uniprotkb/F1N6T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6T5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6T5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGACVLLLLGLQLQLSLGLIPVEEEDPAFWNCQAAQALDVAKKLQPIQTAAKNVILFLGDGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLCGVKGNYKTIGVSAAARYNQCNTTSGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDASVNGVRKDKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQDHTKDPTLQEMTEVALRVLSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAVMFDNAIAKANELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYALGGGSRPDVNDSTSEDPSYQQQAAVPLASETHGGEDVAVFARGPQAHLVHGVQEETFVAHIMAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY", "length": 533, "header": "tr|A0A3Q1LSG5-1|A0A3Q1LSG5_BOVIN Isoform 1 of Alkaline phosphatase OS=Bos taurus OX=9913 GN=LOC100125266 PE=3 SV=2 CANONICAL=A0A3Q1LSG5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5/entry", "sequence": { "sequence": "MQGACVLLLLGLQLQLSLGLIPVEEEDPAFWNCQAAQALDVAKKLQPIQTAAKNVILFLGDGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLCGVKGNYKTIGVSAAARYNQCNTTSGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDASVNGVRKDKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQDHTKDPTLQEMTEVALRVLSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAVMFDNAIAKANELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYALGGGSRPDVNDSTSEDPSYQQQAAVPLASETHGGEDVAVFARGPQAHLVHGVQEETFVAHIMAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY", "length": 533, "header": "tr|A0A3Q1LSG5-1|A0A3Q1LSG5_BOVIN Isoform 1 of Alkaline phosphatase OS=Bos taurus OX=9913 GN=LOC100125266 PE=3 SV=2 CANONICAL=A0A3Q1LSG5-1" }, "locus": { "chromosome": "2", "start_pos": 120105450, "end_pos": 120097013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084059.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084059.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063305.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063305.2" } ] } }, { "isoform_ac": "A0A3Q1MG33-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG33/entry", "sequence": { "sequence": "MQGACVLLLLGLQLQLSLGLIPVEEEDPAFWNCQAAQALDVAKKLQPIQTAAKNVILFLGDGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLCGVKGNYKTIGVSAAARYNQCNTTSGNEVTSVMNRAKKAGKAVGVVTTSRVQHASPAGAYAHTVNRNWYSDADLPADAQMNGCQDIATQLVYNMDIDVILGGGRMYMFPEGTPDPEYPYDVNQTGVRKDKRNLVQEWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQDHTKDPTLQEMTEVALRVLSRNPRGFYLFVEGGRIDHGHHEGKAYMALTDTVMFDNAIAKANELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYALGGGSRPDVNDSTSEDPSYQQQAAVPLASETHGGEDVAVFARGPQAHLVHGVQEETFVAHIMAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY", "length": 533, "header": "tr|A0A3Q1MG33-1|A0A3Q1LSG5_BOVIN Computationally mapped isoform of Alkaline phosphatase OS=Bos taurus OX=9913 GN=LOC100125266 PE=3 SV=2 CANONICAL=A0A3Q1LSG5-1" }, "locus": { "chromosome": "2", "start_pos": 120105450, "end_pos": 120097013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073739.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073739.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069504.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069504.2" } ] } }, { "isoform_ac": "F1N2M5-1", "url": "https://www.uniprot.org/uniprotkb/F1N2M5/entry", "sequence": { "sequence": "MQGACVLLLLGLQLQLSLGLIPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLGDGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLCGVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDASVNGVRKDKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQDHTKDPTLQEMTEVALRVLSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAVMFDNAIAKANELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYALGGGSRPDVNDSTSEDPSYQQQAAVPLASETHGGEDVAVFARGPQAHLVHGVQEETFVAHIMAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY", "length": 533, "header": "tr|F1N2M5-1|A0A3Q1LSG5_BOVIN Computationally mapped isoform of Alkaline phosphatase OS=Bos taurus OX=9913 GN=LOC100125266 PE=3 SV=2 CANONICAL=A0A3Q1LSG5-1" }, "locus": { "chromosome": "2", "start_pos": 120105450, "end_pos": 120097013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043359.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043359.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040934.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040934.4" } ] } }, { "isoform_ac": "F1N6T5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6T5/entry", "sequence": { "sequence": "MQGACVLLLLGLHLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLGDGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLCGVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDASVNGVRKDKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQDHTKDPTLQEMTEVALRVLSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAVMFDNAIAKANELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYALGGGSRPDVNDSTSEDPSYQQQAAVPLASETHGGEDVAVFARGPQAHLVHGVQEETFVAHIMAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY", "length": 533, "header": "tr|F1N6T5-1|A0A3Q1LSG5_BOVIN Computationally mapped isoform of Alkaline phosphatase OS=Bos taurus OX=9913 GN=LOC100125266 PE=3 SV=1 CANONICAL=A0A3Q1LSG5-1" }, "locus": { "chromosome": "2", "start_pos": 120105450, "end_pos": 120102534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005937.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005937.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005937.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005937.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:280993", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:280993", "resource": "KEGG Pathway" }, { "id": "R-BTA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z2E4-1", "protein_name": "Alkaline phosphatase", "gene_name": "ALPI", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLLVALTLCLGLWAELGAAIIPVEEEDPSFWNRQAAAALDATLKIEPRMTEAKNLIIFLGDGFGVPSITATRILKGQLKGNLGPETPLALDSFPYVALSKTYTVDRAVPDSAGTATAYLCGVKGNYKTVGLSAAARYGQCNTTKGNEVISVLERARNAGKAVGIVTTSRVQHASPSGTYAHVVDRNWYADSSMPAEAIAQGCKDIAWQLVHNVDINVIMGGGRVYMTPAGTPDPEYPEYSSENGIRNDGQNLIEKWLSERQGARYVWNRTEMLAAAADPSVTYLMGLFEPMDMKYEMVHNATLDPSLTEMTEAAITILSRNPKGFYLFVEGGRIDHGHHEGMAQRALTEAVEFDTAIERAGELLDEADTLTVVTADHSHVFSFGGYILRGTSILGLAPQKAVDNKTYTSILYGNGPGYPGATRPNVSSSTAGEFNYTQQAAVPLNSETHGGEDVAILAKGPMAYLFHGVQEQNYIAHAMAYAACLEPYENCRQRNSAAPSTHLTPLALLLPALLLSLFH", "length": 520 }, "evidence": [ { "id": "A0A3Q1LSG5", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F8VPQ6-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alpi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGDWVLLLFLGLRIHLSFGIIPAEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDLFPYMALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDAEMPASALQDGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPSDSNQSGTRLDDQNLVQTWLSKHQGARYVWNRSELIQASQDPAVTHLMGLFEPTEMKYDANRNPSVDPSLAEMTEVAVRMLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTLRGTSIFGLAPLKALDDKSYTSILYGNGPGYELKSGNRPNVTEAQSVDPNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAGQSPVITPGQATTTNNAAGQATTTNNAAGQATVLLSLQLLVSMLLLVGTAMVVS", "length": 554 }, "evidence": [ { "id": "A0A3Q1LSG5", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M9PD70-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRALRFFAALALQLTACSSQYKYGPEQSWDLDSISELKSKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTADVELNDCRGSRLPQNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGNCPDIAQQLIDGDVGKRLRVVMGGGTIKFLPNTTNDVFGNKGQRLDNRNLIEEWQQTKPGNARVVFSRTDLLNNDAQNTDFLLGLFNASHLAYHMDDSIDTPTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYKSTDGVVERVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYAHVVEYLLQGPWSHLFTGVYEQSTLPHLMGFASCLGPGITYCDLQPKARYSP", "length": 530 }, "evidence": [ { "id": "A0A3Q1LSG5", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P09923-1", "protein_name": "Intestinal-type alkaline phosphatase", "gene_name": "ALPI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP", "length": 528 }, "evidence": [ { "id": "A0A3Q1LSG5", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15693-1", "protein_name": "Intestinal-type alkaline phosphatase 1", "gene_name": "Alpi", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS", "length": 540 }, "evidence": [ { "id": "A0A3Q1LSG5", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alkaline phosphatase activity", "id": "GO:0004035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004035", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15017", "name": "", "equation": "a phosphate monoester + H2O = an alcohol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6Z8C2-1", "F1MUZ7-1", "E1B8A0-1", "A0AAF6Z8S7-1", "P09487-1", "A6H730-1", "P19111-1", "P11064-1", "A0A3Q1MCB1-1", "Q0P5F0-1", "A0A3Q1LSG5-1", "A0AAA9T5N9-1", "A0A3Q1N8V6-1", "A6H757-1" ], "evidence": [ { "id": "15017", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15017" } ] }, { "id": "R-BTA-8940388", "name": "GPLD1 hydrolyses GPI-anchors from proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-2197633" ], "enzyme_list": [ "F1MLP3-1", "A0A3Q1LSG5-1", "P09487-1", "E1B735-1", "A0AAA9S718-1", "F1MNM2-1", "F1MPH8-1", "A0A140T891-1", "A0A3Q1MCB1-1", "E1BJE3-1" ], "evidence": [ { "id": "R-BTA-8940388", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8940388" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2197633", "participant_name": "PI [extracellular region]", "crossref": [ { "id": "57880", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T891", "gene_name": "VNN1", "activity": [ { "ec_number": "3.5.1.92", "activity": "(R)-pantetheine + H2O = cysteamine + (R)-pantothenate.", "evidence": [ { "id": "A0A140T891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T891" } ] }, { "ec_number": "3.5.1.92", "activity": "", "evidence": [ { "id": "A0A140T891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T891" } ] } ] }, { "uniprot_ac": "A0A3Q1LSG5", "gene_name": "LOC100125266", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" } ] } ] }, { "uniprot_ac": "A0A3Q1MCB1", "gene_name": "", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1MCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB1" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "A0A3Q1MCB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB1" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9S718", "gene_name": "SMCO3", "activity": [ { "ec_number": "2.4.2.31", "activity": "L-arginyl-[protein] + NAD(+) = N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide + H(+).", "evidence": [ { "id": "A0AAA9S718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S718" } ] }, { "ec_number": "2.4.2.31", "activity": "", "evidence": [ { "id": "A0AAA9S718", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S718" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A0AAF6Z8S7", "gene_name": "ACP2", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8S7" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8S7" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A6H757", "gene_name": "ACP6", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] }, { "ec_number": "3.1.3.106", "activity": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] }, { "ec_number": "3.1.3.106", "activity": "", "evidence": [ { "id": "A6H757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H757" } ] } ] }, { "uniprot_ac": "E1B735", "gene_name": "XPNPEP2", "activity": [ { "ec_number": "3.4.11.9", "activity": "Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.", "evidence": [ { "id": "E1B735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B735" } ] }, { "ec_number": "3.4.11.9", "activity": "", "evidence": [ { "id": "E1B735", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B735" } ] } ] }, { "uniprot_ac": "E1B8A0", "gene_name": "ACP5", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "E1B8A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8A0" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "E1B8A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8A0" } ] } ] }, { "uniprot_ac": "E1BJE3", "gene_name": "LOC516378", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "E1BJE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "E1BJE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJE3" } ] } ] }, { "uniprot_ac": "F1MLP3", "gene_name": "BST1", "activity": [ { "ec_number": "3.2.2.6", "activity": "NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+).", "evidence": [ { "id": "F1MLP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLP3" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "F1MLP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLP3" } ] } ] }, { "uniprot_ac": "F1MNM2", "gene_name": "GPLD1", "activity": [ { "ec_number": "3.1.4.50", "activity": "[protein]-C-terminal carboxyl phosphoethanolamide-(1-radyl-2-octadecanoyl)-GPI(deacylinositol-H7) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-glycosylinositol (deacylinositol-H7) + 1-radyl-2-octadecanoyl-sn-glycero-3-phosphate + H(+).", "evidence": [ { "id": "F1MNM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNM2" } ] }, { "ec_number": "3.1.4.50", "activity": "", "evidence": [ { "id": "F1MNM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNM2" } ] } ] }, { "uniprot_ac": "F1MPH8", "gene_name": "LOC528262", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1MPH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPH8" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1MPH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPH8" } ] } ] }, { "uniprot_ac": "F1MUZ7", "gene_name": "ACP7", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1MUZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUZ7" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "F1MUZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUZ7" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P11064", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P11064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11064" } ] } ] }, { "uniprot_ac": "P19111", "gene_name": "ALPI", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P19111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19111" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P19111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19111" } ] } ] }, { "uniprot_ac": "Q0P5F0", "gene_name": "ACP2", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q0P5F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5F0" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "Q0P5F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5F0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LSG5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 533, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LSG5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LSG5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" }, { "id": "PIRSR601952-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601952-2" } ], "binding_site_uniprot": 172, "amino_acid": "His", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 172, "end_pos": 172, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG5" }, { "id": "PIRSR601952-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601952-2" } ], 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"https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKT6", "url": "https://www.orthodb.org/?gene=A0A3Q1LKT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LW14", "url": "https://www.orthodb.org/?gene=A0A3Q1LW14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MKK0", "url": "https://www.orthodb.org/?gene=A0A3Q1MKK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BNK4", "url": "https://www.orthodb.org/?gene=E1BNK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10241:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10241:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08596", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08596", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005211084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005211084", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKT6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LW14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMC8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMC8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNK4", "url": "https://www.uniprot.org/uniprotkb/E1BNK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNK4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKFNIRKVLDGLTAGSSSASQQQQQQQHPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDSGAAVIQLQFLINEGALVSALADDTLHLWNLRQKRPAILHSLKFCRERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWNKAIELSSKSHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIWNVRSPAKPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFIILSGGLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSKKEWPINGGNWGLGAQSYSEIIITGHADGSIKFWDASAITLQVLYKLKTSKVFEKSRNKDEKPNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVITEVIPMLEVRLLYEISDVETPEGEQAPPLPTPVGSANPQPIPPQSHPSTSSSSSDGLRDNVPCLKVKSSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKAVLLNLGTIELYGSNDPYRREPRSPRKSRQPSGAGLCDISEGAVVPEDRCKSPTSAKMSRKLSLPTDLKPDLDIKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKTDSAPSPCLWVGTTLGTVLVIALNLPPGGEQRLLQPVIVSPSGTILRLKGAILRMAFLDSTGCLVPPAHEPWKEHNVPEEKDEKEKLKKRRPVSVSPSSSQEISENQYAVICSEKQAKVISLPSQNCAYKQNITETSFVLRGDIVSLSNSICLACFCANGHIMTFSLPSLRPLLDVYYLPLTNMRIARTFCFTNNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLSDLEERTAAMLSSADSFSKHAHEMMLKYKDKKWYQF", "length": 1116, "header": "tr|A0A3Q1LW14-1|A0A3Q1LW14_BOVIN Isoform 1 of Syntaxin-binding protein 5 OS=Bos taurus OX=9913 GN=STXBP5 PE=3 SV=1 CANONICAL=A0A3Q1LW14-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKT6/entry", "sequence": { "sequence": 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"length": 1136, "header": "tr|A0A3Q1LKT6-1|A0A3Q1LW14_BOVIN Computationally mapped isoform of Syntaxin-binding protein 5 OS=Bos taurus OX=9913 GN=STXBP5 PE=3 SV=1 CANONICAL=A0A3Q1LW14-1" }, "locus": { "chromosome": "9", "start_pos": 84660648, "end_pos": 84506918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073234.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073234.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057082.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057082.1" } ] } }, { "isoform_ac": "A0A3Q1LW14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14/entry", "sequence": { "sequence": 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"length": 1116, "header": "tr|A0A3Q1LW14-1|A0A3Q1LW14_BOVIN Isoform 1 of Syntaxin-binding protein 5 OS=Bos taurus OX=9913 GN=STXBP5 PE=3 SV=1 CANONICAL=A0A3Q1LW14-1" }, "locus": { "chromosome": "9", "start_pos": 84660648, "end_pos": 84506918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083985.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083985.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059562.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059562.1" } ] } }, { "isoform_ac": "A0A3Q1MKK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKK0/entry", "sequence": { "sequence": "MRKFNIRKVLDGLTAGSSSASQQQQQQQHPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDSGAAVIQLQFLINEGALVSALADDTLHLWNLRQKRPAILHSLKFCRERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWNKAIELSSKSHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIWNVRSPAKPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFIILSGGLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSKKEWPINGGNWGLGAQSYSEIIITGHADGSIKFWDASAITLQVLYKLKTSKVFEKSRNKDEKPNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVITEVIPMLEVRLLYEISDVETPEGEQAPPLPTPVGSANPQPIPPQSHPSTSSSSSDGLRDNVPCLKVKSSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKAVLLNLGTIELYGSNDPYRREPRSPRKSRQPSGAGLCDISEGAVVPEDRCKSPTSDIKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKTDSAPSPCLWVGTTLGTVLVIALNLPPGGEQRLLQPVIVSPSGTILRLKGAILRMAFLDSTGCLVPPAHEPWKEHNVPEEKDEKEKLKKRRPVSVSPSSSQEISENQYAVICSEKQAKVISLPSQNCAYKQNITETSFVLRGDIVSLSNSICLACFCANGHIMTFSLPSLRPLLDVYYLPLTNMRIARTFCFTNNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLSDLEERTAAMLSSADSFSKHAHEMMLKYKDKKWYQF", "length": 1099, "header": "tr|A0A3Q1MKK0-1|A0A3Q1LW14_BOVIN Computationally mapped isoform of Syntaxin-binding protein 5 OS=Bos taurus OX=9913 GN=STXBP5 PE=3 SV=1 CANONICAL=A0A3Q1LW14-1" }, "locus": { "chromosome": "9", "start_pos": 84660648, "end_pos": 84506918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082509.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082509.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069753.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069753.1" } ] } }, { "isoform_ac": "A0AAA9SMC8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMC8/entry", "sequence": { "sequence": "MRKFNIRKVLDGLTAGSSSASQQQQQQQHPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDSGAAVIQLQFLINEGALVSALADDTLHLWNLRQKRPAILHSLKFCRERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWNKAIELSSKSHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIWNVRSPAKPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFIILSGGLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSKKEWPINGGNWGLGAQSYSEIIITGHADGSIKFWDASAITLQVLYKLKTSKVFEKSRNKDEKPNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVITEVIPMLEVRLLYEISDVETPEGEQAPPLPTPVGSANPQPIPPQSHPSTSSSSSDGLRDNVPCLKVKSSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKAVLLNLGTIELYGSNDPYRREPRSPRKSRQPSGAGLCDISEGAVVPEDRCKSPTSAKMSRKLSLPTDLKPDLDIKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKTDSAPSPCLWVGTTLGTVLVIALNLPPGGEQRLLQPVIVSPSGTILRLKGAILRMAFLDSTGCLVPPAHEPWKEHNVPEEKDEKEKLKKRRPVSVSPSSSQEISENQYAVICSEKQAKVISLPSQNCAYKQNITETSFVLRGDIVSLSNSICLACFCANGHIMTFSLPSLRPLLDVYYLPLTNMRIARTFCFTNNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELYDSPACRKSSGNHTHSGSLLVVRTQRFHCCGPGLNPCLGNKILQAALCSQNKILIKK", "length": 1086, "header": "tr|A0AAA9SMC8-1|A0A3Q1LW14_BOVIN Computationally mapped isoform of Syntaxin-binding protein 5 OS=Bos taurus OX=9913 GN=STXBP5 PE=3 SV=1 CANONICAL=A0A3Q1LW14-1" }, "locus": { "chromosome": "9", "start_pos": 84655880, "end_pos": 84506918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093047.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093047.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086444.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086444.1" } ] } }, { "isoform_ac": "E1BNK4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNK4/entry", "sequence": { "sequence": "MRKFNIRKVLDGLTAGSSSASQQQQQQQHPPGNREPEIQETLQSEHFQLCKTVRHGFPYQPSALAFDPVQKILAVGTQTGALRLFGRPGVECYCQHDSGAAVIQLQFLINEGALVSALADDTLHLWNLRQKRPAILHSLKFCRERVTFCHLPFQSKWLYVGTERGNIHIVNVESFTLSGYVIMWNKAIELSSKSHPGPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIWNVRSPAKPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSGEPFIILSGGLSYDTVGRRPCLTVMHGKSTAVLEMDYSIVDFLTLCETPYPNDFQEPYAVVVLLEKDLVLIDLAQNGYPIFENPYPLSIHESPVTCCEYFADCPVDLIPALYSVGARQKRQGYSKKEWPINGGNWGLGAQSYSEIIITGHADGSIKFWDASAITLQVLYKLKTSKVFEKSRNKDEKPNTDIVDEDPYAIQIISWCPESRMLCIAGVSAHVIIYRFSKQEVITEVIPMLEVRLLYEISDVETPEGEQAPPLPTPVGSANPQPIPPQSHPSTSSSSSDGLRDNVPCLKVKSSPLKQSPGYQTELVIQLVWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKAVLLNLGTIELYGSNDPYRREPRSPRKSRQPSGGLCDISEGAVVPEDRCKSPTSGSPSPHNSDDEQKMNNFIEKVKIKSRKFSKMVASDIAKMSRKLSLPTDLKPDLDIKDNSFSRSRSSSVTSIDKESREAISALHFCETFTRKTDSAPSPCLWVGTTLGTVLVIALNLPPGGEQRLLQPVIVSPSGTILRLKGAILRMAFLDSTGCLVPPAHEPWKEHNVPEEKDEKEKLKKRRPVSVSPSSSQEISENQYAVICSEKQAKVISLPSQNCAYKQNITETSFVLRGDIVSLSNSICLACFCANGHIMTFSLPSLRPLLDVYYLPLTNMRIARTFCFTNNGQALYLVSPTEIQRLTYSQETCENLQEMLGELFTPVETPEAPNRGFFKGLFGGGAQSLDREELFGESSSGKASRSLAQHIPGPGGIEGVKGAASGVVGELARARLALDERGQKLSDLEERTAAMLSSADSFSKHAHEMMLKYKDKKWYQF", "length": 1151, "header": "tr|E1BNK4-1|A0A3Q1LW14_BOVIN Computationally mapped isoform of Syntaxin-binding protein 5 OS=Bos taurus OX=9913 GN=STXBP5 PE=3 SV=2 CANONICAL=A0A3Q1LW14-1" }, "locus": { "chromosome": "9", "start_pos": 84660648, "end_pos": 84506918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061280.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061280.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053504.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053504.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 568, "start_aa": "Thr", "end_pos": 568, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr568", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "acetylcholine-gated channel complex", "id": "GO:0005892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005892", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "extrinsic component of neuronal dense core vesicle membrane", "id": "GO:0098674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098674", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "hippocampal mossy fiber to CA3 synapse", "id": "GO:0098686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098686", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle priming", "id": "GO:0010807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010807", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "positive regulation of exocytosis", "id": "GO:0045921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045921", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "myosin II binding", "id": "GO:0045159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045159", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" }, { "name": "syntaxin-1 binding", "id": "GO:0017075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017075", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LW14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LW14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW14" }, { "id": "PS50892", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "V-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 1051, "end_pos": 1111, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LSG7-1", "uniprot_ac": "A0A3Q1LSG7", "uniprot_id": "A0A3Q1LSG7_BOVIN", "mass": { "chemical_mass": 61995.0, "monoisotopic_mass": 61995.0 }, "refseq": {}, "gene_names": [ { "name": "LMBRD1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LSG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7" } ] } ], "protein_names": [ { "name": "Lysosomal cobalamin transport escort protein LMBD1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LSG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7/entry#names_and_taxonomy" } ] }, { "name": "LMBR1 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LSG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LMBRD1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7", "locus": { "chromosome": "9", "start_pos": 8607152, "end_pos": 8739448, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016164", "url": "https://www.ensembl.org/id/ENSBTAG00000016164" } ] } } ], "crossref": [ { "id": "A0A3Q1LSG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LSG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016164", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016164", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FWAQFVF", "url": "https://omabrowser.org/oma/group/FWAQFVF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSG7", "url": "https://www.orthodb.org/?gene=A0A3Q1LSG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N364", "url": "https://www.orthodb.org/?gene=F1N364", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16130:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16130:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9758881", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758881", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9758890", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758890", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LSG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXY1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N364", "url": "https://www.uniprot.org/uniprotkb/F1N364", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N364-1", "url": "https://www.uniprot.org/uniprotkb/F1N364-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAGAASAELVIGWCIFGLLLLAILAFCWIYVRKYQSQRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANGNVSRQIEDTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTGKCTQVKMALKYTLGFVVICALLLLVGAFVPLNLPDNKNSTEWEKVKFLFEELGSSHGLAALSFSISSLTLVGMLAAIIYTAYGMSALPLNLIKGTRNAAYERLENTEDIEEVEQHIQTIKSKSKDGRPLPARDRRALKQFEERLRTLRKRERRLEFIENSWWTKFCGALRPLKIIWGIFFIFVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIESNMTYSDHRGNSSLSVPKRCDADAPEDQCTVTRTYLFLHKFWFFSAAYYFGNWAFLGVFIVGFIVSCCKGKKSVLERVDEDDSDLSDDEPSLYSV", "length": 543, "header": "tr|A0A3Q1LSG7-1|A0A3Q1LSG7_BOVIN Isoform 1 of Lysosomal cobalamin transport escort protein LMBD1 OS=Bos taurus OX=9913 GN=LMBRD1 PE=3 SV=2 CANONICAL=A0A3Q1LSG7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7/entry", "sequence": { "sequence": "MAAAAAGAASAELVIGWCIFGLLLLAILAFCWIYVRKYQSQRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANGNVSRQIEDTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTGKCTQVKMALKYTLGFVVICALLLLVGAFVPLNLPDNKNSTEWEKVKFLFEELGSSHGLAALSFSISSLTLVGMLAAIIYTAYGMSALPLNLIKGTRNAAYERLENTEDIEEVEQHIQTIKSKSKDGRPLPARDRRALKQFEERLRTLRKRERRLEFIENSWWTKFCGALRPLKIIWGIFFIFVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIESNMTYSDHRGNSSLSVPKRCDADAPEDQCTVTRTYLFLHKFWFFSAAYYFGNWAFLGVFIVGFIVSCCKGKKSVLERVDEDDSDLSDDEPSLYSV", "length": 543, "header": "tr|A0A3Q1LSG7-1|A0A3Q1LSG7_BOVIN Isoform 1 of Lysosomal cobalamin transport escort protein LMBD1 OS=Bos taurus OX=9913 GN=LMBRD1 PE=3 SV=2 CANONICAL=A0A3Q1LSG7-1" }, "locus": { "chromosome": "9", "start_pos": 8739433, "end_pos": 8607502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078634.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078634.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060189.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060189.2" } ] } }, { "isoform_ac": "A0AAA9TXY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXY1/entry", "sequence": { "sequence": "MAAAAAGAASAELVIGWCIFGLLLLAILAFCWIYVRKYQSQRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKTLFSCPGKPPLTVSRLPSHELPQNHLLTLAHIYLLMQLSFYSSVADFLKAQTIPDWANGNVSRQIEDTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTGKCTQVKMALKYTLGFVVICALLLLVGAFVPLNLPDNKNSTEWEKVKFLFEELGSSHGLAALSFSISSLTLVGMLAAIIYTAYGMSALPLNLIKGTRNAAYERLENTEDIEEVEQHIQTIKSKSKDGRPLPARDRRALKQFEERLRTLRKRERRLEFIENSWWTKFCGALRPLKIIWGIFFIFVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIESNMTYSDHRGNSSLSVPKRCDADAPEDQCTVTRTYLFLHKFWFFSAAYYFGNWAFLGVFIVGFIVSCCKGKKSVLERVDEDDSDLSDDEPSLYSV", "length": 597, "header": "tr|A0AAA9TXY1-1|A0A3Q1LSG7_BOVIN Computationally mapped isoform of Lysosomal cobalamin transport escort protein LMBD1 OS=Bos taurus OX=9913 GN=LMBRD1 PE=3 SV=1 CANONICAL=A0A3Q1LSG7-1" }, "locus": { "chromosome": "9", "start_pos": 8739433, "end_pos": 8607502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128126.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128126.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103518.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103518.1" } ] } }, { "isoform_ac": "F1N364-1", "url": "https://www.uniprot.org/uniprotkb/F1N364/entry", "sequence": { "sequence": "MYREKYSELVITVMCQPLMAILAFCWIYVRKYQSQRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANGNVSRQIEDTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTGKCTQVKMALKYTLGFVVICALLLLVGAFVPLNLPDNKNSTEWEKVKFLFEELGSSHGLAALSFSISSLTLVGMLAAIIYTAYGMSALPLNLIKGTRNAAYERLENTEDIEEVEQHIQTIKSKSKDGRPLPARDRRALKQFEERLRTLRKRERRLEFIENSWWTKFCGALRPLKIIWGIFFIFVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIESNMTYSDHRGNSSLSVPKRCDADAPEDQCTVTRTYLFLHKFWFFSAAYYFGNWAFLGVFIVGFIVSCCKGKKSVLERVDEDDSDLSDDEPSLYSV", "length": 537, "header": "tr|F1N364-1|A0A3Q1LSG7_BOVIN Computationally mapped isoform of Lysosomal cobalamin transport escort protein LMBD1 OS=Bos taurus OX=9913 GN=LMBRD1 PE=3 SV=2 CANONICAL=A0A3Q1LSG7-1" }, "locus": { "chromosome": "9", "start_pos": 8730371, "end_pos": 8607502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021518.4", "url": "https://www.ensembl.org/id/ENSBTAT00000021518.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021518.3", "url": "https://www.ensembl.org/id/ENSBTAP00000021518.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9758881", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758881", "resource": "Reactome", "description": "Uptake of dietary cobalamins into enterocytes" }, { "id": "R-BTA-9758890", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9758890", "resource": "Reactome", "description": "Transport of RCbl within the body" } ], "orthologs": [ { "uniprot_canonical_ac": "Q54KD1-1", "protein_name": "Probable lysosomal cobalamin transporter", "gene_name": "lmbrd1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFPISVGWIAFAGVLLTLIALNYFIVKYYSDKHESGKITTIISVIGLTLTLLCVMLIPVDILNVSTMSHSDGTQISPYSISQRTEGVKMLYYILYGSILGVSLILVPFAYFYHEEYDENIPTCSRVYAGCKFTIFFILFTIILLVVGAFVRPGSKPIDDQNVKDWINDEVLNQNAIESSVLFAISCLTVLGFLVFAVYTSYGLSAFPIGLIKGKKRTDDDKSDINKDLWKAKEKSSFYSSKYASGKSLSEKEQSTLSLLRGKERALSKRSERLDNSNKGFRKILVIFRPFAFIFGFIFILVSLLIIISIVLSLVDKISSSVCGSACGFLSTYPQLKNPFDIILTKLAPYFPLDYIIIGGLIFFIYSCTLSGITRIGIRFLWINMFEFGYRKTFPQGLLLASVLLMLSNLCLNMQIVNLAPRYVMYGAQVYLNGTSVIPCTINAPTDLCIMSEIGLLTSRIQLGISFFGIVFYYGTWVIVATFILGLAVSIFKRRPSAALSYSGDSDEEEI", "length": 510 }, "evidence": [ { "id": "A0A3Q1LSG7", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6AZ61-1", "protein_name": "Lysosomal cobalamin transport escort protein LMBD1", "gene_name": "Lmbrd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAADLVIGWCIFGLLLLAILAFCWVYVRKYQSQRESEVVSTVTAIFSLAVALITSALLPVDIFLVSYMKNQNGTFKDWANANVTVQIENTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTSKCTQVKTALKYTLGFVVICALLLLVGAFVPLNLPNNNNSTEWEKVKLLFEDLGTGQGLAALSFSISSLTLIGMLAAITYTAYGMSALPLNLIKGTRSTAYERLENTEDIEEVEQHIQTIRSKSKDGRPLSARDRRTLKQCEERLRTLRKRERHLEFIENSWWTKFCGALRPLKIIWGIFFILVALLFVISLFLSNLDKALHSAGIDSGFIVFGTNLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIESNITSDAHKGNSTLAVPKRCDADAPKDQCTVTRTYVFLHKFWFFSAAYYFGNWAFLVVFLIGLIVSCCKGKKSVIEGVDEDSDLSDDEPSAYSA", "length": 537 }, "evidence": [ { "id": "A0A3Q1LSG7", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K0B2-1", "protein_name": "Lysosomal cobalamin transport escort protein LMBD1", "gene_name": "Lmbrd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAAELVIGWCIFGLLLLAILAFCWVYVRKYQSQRESEVVSTVTAIFSLAVALITSALLPVDIFLVSYMKNQNGTFKDWADANVTVQIENTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDEDDASKCTQIKTALKYTLGFVVICALLLLVGAFVPLHLPNNNNSTEWEKVKLLFEDLGTGQGLAALSFSISSLTLIGMLAAITYTAYGMSALPLNLIKGTRSTAYERLENTEDIEEVEQHIQTIRSKSKDGRPLPARDRRALKQCEERLRTLRKRERHLEFIENSWWTKFCGALRPLKIIWGIFFILVALLFVISLFLSNLDKALHSAGIDSGFIIFGTNLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIESNITSDAHKGNSTLAVPKRCDADAPKDQCTVTRTYIFLHKFWFFSAAYYFGNWAFLVVFLIGLIVSCCKGKKSVIEGVDEDSDLSDDEPSAYSA", "length": 537 }, "evidence": [ { "id": "A0A3Q1LSG7", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUN5-1", "protein_name": "Lysosomal cobalamin transport escort protein LMBD1", "gene_name": "LMBRD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSGAASAELVIGWCIFGLLLLAILAFCWIYVRKYQSRRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANANVSRQIEDTVLYGYYTLYSVILFCVFFWIPFVYFYYEEKDDDDTSKCTQIKTALKYTLGFVVICALLLLVGAFVPLNVPNNKNSTEWEKVKSLFEELGSSHGLAALSFSISSLTLIGMLAAITYTAYGMSALPLNLIKGTRSAAYERLENTEDIEEVEQHIQTIKSKSKDGRPLPARDKRALKQFEERLRTLKKRERHLEFIENSWWTKFCGALRPLKIVWGIFFILVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPLLQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQNYLIETNITSDNHKGNSTLSVPKRCDADAPEDQCTVTRTYLFLHKFWFFSAAYYFGNWAFLGVFLIGLIVSCCKGKKSVIEGVDEDSDISDDEPSVYSA", "length": 540 }, "evidence": [ { "id": "A0A3Q1LSG7", "url": "https://omabrowser.org/oma/group/A0A3Q1LSG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7" } ], "pmid": "" }, { "name": "AP-2 adaptor complex binding", "id": "GO:0035612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035612", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7" } ], "pmid": "" }, { "name": "cobalamin binding", "id": "GO:0031419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031419", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7" } ], "pmid": "" }, { "name": "clathrin heavy chain binding", "id": "GO:0032050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032050", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG7" } ], "pmid": "" }, { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSG7", 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], "sequence": { "sequence": "MPISPVNGRRQPNVGVNVGLGPRKSISFVGPGKGALMKGGYAGANQSRMAMSKNMMILPEAKQMEKMTISSAKTVTQVTDIHGVDVTPKPLYRPDPYSGTGKPNKLLTSQDGSHTSDFIASYSLYQNTINPSMLGQFTRSVLGSSTVSKSSVSTSESMAEDLEEPSFKRERLSSFTDLRVMRTAPGKIITKEDLEKTVEIILTETETMNFLNLPTVMFSVESEEAEKVSQRNKNYETLCRNRLGNDLYVERMMQTINGAPKNKDVQCDKILKEDKGIMSTAWDLYDSYNAMELSSLPPKRSMIDSSSKANVPTKDWEQTVAGSNLEKISEGSSLMDIENVILAKVRDEEEDNSDAVFKSDKFQQDLFFMERVIMENIFQPKLAAYRQLPILKEPEPEEPGDFLVDGKLEVVEEEAKKEEEEDLEISSEQSTIPANLERLWSFSCDLTKGLNVSSLAWNKANPDLLAVGYGHFGFKEQKRGLACCWSIKNPMWPERTYQSPYGVTAVDFSIGSPNLLAVGYHNGTIAIYNVQNNSNLPVLDSSESPQKHLGPVWQLQWIEQDRGTTGDDKREILVSISADGRISKWVIRKGLDCHDLMRLRRTTASTSKKGGEKEKKGEALISRQAPGMCFAFHPKDTNIYLAGTEEGHIHKCSCSYNEQYLDTYRGHKGPVYKIAWNPFCHDVFLSCSADWGVIIWQHENLKPFLSFYPTTYVVYDIAWSPKSSYIFAAANESRVEIWDLHISTLDPLIVNVANPGIKFTTVLFAKQTDCLLVGDSDGQVAVYELKNMPTTLDSNRGDVIVTLLGPKSSQSIIHHQ", "length": 816, "header": "tr|A0A3Q1LT75-1|A0A3Q1LT75_BOVIN Isoform 1 of Dynein axonemal intermediate chain 4 OS=Bos taurus OX=9913 GN=DNAI4 PE=1 SV=2 CANONICAL=A0A3Q1LT75-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFE0/entry", "sequence": { "sequence": "MPISPVNGRRQPNVGVNVGLGPRKSISFVGPGKGALMKGGYAGANQSRMAMSKNMMILPEAKQMEKMTISSAKTVTQVTDIHGVDVTPKPLYRPDPYSGTGKPNKLLTSQDGSHTSDFIASYSLYQNTINPSMLGQFTRSVLGSSTVSKSSVSTSESMAEDLEEPSFKRERLSSFTDLRVMRTAPGKIITKEDLEKTVEIILTETETMNFLNLPTVMFSVESEEAEKVSQRNKNYETLCRNRLGNDLYVERMMQTINGAPKNKDVQCDKILKEDKGIMSTAWDLYDSYNAMELSSLPPKRSMIDSSSKANVPTKDWEQTVAGSNLEKKPEPEEPGDFLVDGKLEVVEEEAKKEEEEDLEISSEQSTIPANLERLWSFSCDLTKGLNVSSLAWNKANPDLLAVGYGHFGFKEQKRGLACCWSIKNPMWPERTYQSPYGVTAVDFSIGSPNLLAVGYHNGTIAIYNVQNNSNLPVLDSSESPQKHLGPVWQLQWIEQDRGTTGDDKREILVSISADGRISKWVIRKGLDCHDLMRLRRTTASTSKKGGEKEKKGEALISRQAPGMCFAFHPKDTNIYLAGTEEGHIHKCSCSYNEQYLDTYRGHKGPVYKIAWNPFCHDVFLSCSADWGVIIWQHENLKPFLSFYPTTYVVYDIAWSPKSSYIFAAANESRVEIWDLHISTLDPLIVNVANPGIKFTTVLFAKQTDCLLVGDSDGQVAVYELKNMPTTLDSNRGDVIVTLLGPKSSQSIIHHQ", "length": 751, "header": "tr|A0A3Q1LFE0-1|A0A3Q1LT75_BOVIN Computationally mapped isoform of Dynein axonemal intermediate chain 4 OS=Bos taurus OX=9913 GN=DNAI4 PE=1 SV=2 CANONICAL=A0A3Q1LT75-1" }, "locus": { "chromosome": "3", "start_pos": 78506844, "end_pos": 78409056, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067939.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067939.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056859.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056859.2" } ] } }, { "isoform_ac": "A0A3Q1LT75-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT75/entry", "sequence": { "sequence": "MPISPVNGRRQPNVGVNVGLGPRKSISFVGPGKGALMKGGYAGANQSRMAMSKNMMILPEAKQMEKMTISSAKTVTQVTDIHGVDVTPKPLYRPDPYSGTGKPNKLLTSQDGSHTSDFIASYSLYQNTINPSMLGQFTRSVLGSSTVSKSSVSTSESMAEDLEEPSFKRERLSSFTDLRVMRTAPGKIITKEDLEKTVEIILTETETMNFLNLPTVMFSVESEEAEKVSQRNKNYETLCRNRLGNDLYVERMMQTINGAPKNKDVQCDKILKEDKGIMSTAWDLYDSYNAMELSSLPPKRSMIDSSSKANVPTKDWEQTVAGSNLEKISEGSSLMDIENVILAKVRDEEEDNSDAVFKSDKFQQDLFFMERVIMENIFQPKLAAYRQLPILKEPEPEEPGDFLVDGKLEVVEEEAKKEEEEDLEISSEQSTIPANLERLWSFSCDLTKGLNVSSLAWNKANPDLLAVGYGHFGFKEQKRGLACCWSIKNPMWPERTYQSPYGVTAVDFSIGSPNLLAVGYHNGTIAIYNVQNNSNLPVLDSSESPQKHLGPVWQLQWIEQDRGTTGDDKREILVSISADGRISKWVIRKGLDCHDLMRLRRTTASTSKKGGEKEKKGEALISRQAPGMCFAFHPKDTNIYLAGTEEGHIHKCSCSYNEQYLDTYRGHKGPVYKIAWNPFCHDVFLSCSADWGVIIWQHENLKPFLSFYPTTYVVYDIAWSPKSSYIFAAANESRVEIWDLHISTLDPLIVNVANPGIKFTTVLFAKQTDCLLVGDSDGQVAVYELKNMPTTLDSNRGDVIVTLLGPKSSQSIIHHQ", "length": 816, "header": "tr|A0A3Q1LT75-1|A0A3Q1LT75_BOVIN Isoform 1 of Dynein axonemal intermediate chain 4 OS=Bos taurus OX=9913 GN=DNAI4 PE=1 SV=2 CANONICAL=A0A3Q1LT75-1" }, 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2 OS=Bos taurus OX=9913 GN=PLPPR2 PE=3 SV=1 CANONICAL=A0A3Q1LQD3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LH66-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH66/entry", "sequence": { "sequence": "MAGGRPQLKRSFSIIPCFVFVESVLLGIVVLLAYRLEFTDTFPVHTQGFFCYDSTYAKPYPGPEATSRAPPALIYALVTAGPTLTVRLVVTRLRLWEGPSRRQEGRWVVGGGLGLKAKKTTPWSCPQILLGELARAFFPAPPSAVPIIGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQGACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSPWEDLSQAPTMDSPLEKLSVAQEPEGCRSHSTPARLTPSKPQNCARRGHLIPNCVSSRAPAMCSSPRVPRPRLRSEPTPLPLPLPLPAPAPSQGPSPSSPGPGGPGGGGGRGRKLLLPTPLLRDLYTLSGLYPSPFHRDNFSPYLFASRDHLL", "length": 494, "header": "tr|A0A3Q1LH66-1|A0A3Q1LQD3_BOVIN Computationally mapped isoform of Phospholipid phosphatase-related protein type 2 OS=Bos taurus OX=9913 GN=PLPPR2 PE=3 SV=2 CANONICAL=A0A3Q1LQD3-1" }, "locus": { "chromosome": "7", "start_pos": 15767191, "end_pos": 15762411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081976.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081976.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058010.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058010.2" } ] } }, { "isoform_ac": "A0A3Q1LQD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQD3/entry", "sequence": { "sequence": "MAGGRPQLKRSFSIIPCFVFVESVLLGIVVLLAYRLEFTDTFPVHTQGFFCYDSTYAKPYPGPEATSRAPPALIYALVTAGPTLTILLGELARAFFPAPPSAVPIIGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQGACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSPWEDLSQAPTMDSPLEKLSVAQEPEGCRSHSTPARLTPSKPQNCARRGHLIPNCVSSRAPAMCSSPRVPRPRLRSEPTPLPLPLPLPAPAPSQGPSPSSPGPGGPGGGGGRGRKLLLPTPLLRDLYTLSGLYPSPFHRDNFSPYLFASRDHLL", "length": 452, "header": "tr|A0A3Q1LQD3-1|A0A3Q1LQD3_BOVIN Isoform 1 of Phospholipid phosphatase-related protein type 2 OS=Bos taurus OX=9913 GN=PLPPR2 PE=3 SV=1 CANONICAL=A0A3Q1LQD3-1" }, "locus": { "chromosome": "7", "start_pos": 15767191, "end_pos": 15762411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070027.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070027.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057169.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057169.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-419408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-419408", "resource": "Reactome", "description": "Lysosphingolipid and LPA receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HST7-1", "protein_name": "Phospholipid phosphatase-related protein type 2", "gene_name": "Plppr2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGGRPHLKRSFSIIPCFVFVESVLLGIVILLAYRLEFTDTFPVHTQGFFCYDSAYAKPYPGPEAASRAPPALIYALVTAGPTFTILLGELARAFFPAPPSASPVSGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQSACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSPWEDLSQAPTMDSPLEKLSVAQEAETCRPHSTPARLTPSKPQNCARRGHLIPSCVSSRAPAMCSSPRVPRPRLRSEPTPLPLPLPLPAPTPSQGPSPSSPGPGGPGGGGGRGRKLLLPTPLLRDLYTLSGLHPSPFHRDNFSPYLFASRDHLL", "length": 452 }, "evidence": [ { "id": "A0A3Q1LQD3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQD3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6W5G4-1", "protein_name": "Phospholipid phosphatase-related protein type 2", "gene_name": "Plppr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGRPHLKRSFSIIPCFVFVESVLLGIVVLLAYRLEFTDTFPVHTQGFFCYDSAYAKPYPGPEAASRAPPALIYALVTAGPTLTILLGELARAFFPAPPSSSPVSGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQSACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPHSGRRLSPWEDLSQAPTMDSPLEKNPRPAGRIRHRHGSPHPSRRTVPAVAT", "length": 343 }, "evidence": [ { "id": "A0A3Q1LQD3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCY8-1", "protein_name": "Phospholipid phosphatase-related protein type 2", "gene_name": "Plppr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGRPHLKRSFSIIPCFVFVESVLLGIVVLLAYRLEFTDTFPVHTQGFFCYDSAYAKPYPGPEAASRAPPALIYALVTAGPTLTILLGELARAFFPAPPSSSPVSGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQSACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPHSGRRLSPWEDLSQAPTMDSPLEKNPRPAGRIRHRHGSPHPSRRTVPAVAT", "length": 343 }, "evidence": [ { "id": "A0A3Q1LQD3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GM1-1", "protein_name": "Phospholipid phosphatase-related protein type 2", "gene_name": "PLPPR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGRPHLKRSFSIIPCFVFVESVLLGIVILLAYRLEFTDTFPVHTQGFFCYDSTYAKPYPGPEAASRVPPALVYALVTAGPTLTILLGELARAFFPAPPSAVPVIGESTIVSGACCRFSPPVRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCLPPSPDRPGPDRFVTDQGACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSPWEDLGQAPTMDSPLEKNPRSAGRIRHRHGSPHPSRRTAPAVAT", "length": 343 }, "evidence": [ { "id": "A0A3Q1LQD3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQD3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQD3" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQD3" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LQD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 452, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LQD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LQD3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LQD3", "database": 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"uniprot_canonical_ac": "A0A3Q1LS50-1", "uniprot_ac": "A0A3Q1LS50", "uniprot_id": "A0A3Q1LS50_BOVIN", "mass": { "chemical_mass": 52701.0, "monoisotopic_mass": 52701.0 }, "refseq": {}, "gene_names": [ { "name": "CYTH1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" } ] } ], "protein_names": [ { "name": "Cytohesin 1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LS50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CYTH1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50", "locus": { "chromosome": "19", "start_pos": 53644769, "end_pos": 53565668, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006663", "url": "https://www.ensembl.org/id/ENSBTAG00000006663" } ] } } ], "crossref": [ { "id": "A0A3Q1LS50", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LS50", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006663", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006663", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01252", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01252", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100141038", "url": "https://www.ncbi.nlm.nih.gov/gene/100141038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKN9", "url": "https://www.orthodb.org/?gene=A0A3Q1LKN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LS50", "url": "https://www.orthodb.org/?gene=A0A3Q1LS50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MCV3", "url": "https://www.orthodb.org/?gene=F1MCV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LKN9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LS50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LS50-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCV3", "url": "https://www.uniprot.org/uniprotkb/F1MCV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCV3-1", "url": "https://www.uniprot.org/uniprotkb/F1MCV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEADWSRRAAREFPGSPGSSSELSQRWTAHRYSRPTRPPRSTHPGSLQGPAVTEKMVLKTEEEDVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNHGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 454, "header": "tr|A0A3Q1LS50-1|A0A3Q1LS50_BOVIN Isoform 1 of Cytohesin 1 OS=Bos taurus OX=9913 GN=CYTH1 PE=4 SV=3 CANONICAL=A0A3Q1LS50-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN9/entry", "sequence": { "sequence": "MDEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNHGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 398, "header": "tr|A0A3Q1LKN9-1|A0A3Q1LS50_BOVIN Computationally mapped isoform of Cytohesin 1 OS=Bos taurus OX=9913 GN=CYTH1 PE=4 SV=3 CANONICAL=A0A3Q1LS50-1" }, "locus": { "chromosome": "19", "start_pos": 53643765, "end_pos": 53565870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070161.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070161.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057037.3", "url": "https://www.ensembl.org/id/ENSBTAP00000057037.3" } ] } }, { "isoform_ac": "A0A3Q1LS50-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50/entry", "sequence": { "sequence": "MEADWSRRAAREFPGSPGSSSELSQRWTAHRYSRPTRPPRSTHPGSLQGPAVTEKMVLKTEEEDVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNHGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 454, "header": "tr|A0A3Q1LS50-1|A0A3Q1LS50_BOVIN Isoform 1 of Cytohesin 1 OS=Bos taurus OX=9913 GN=CYTH1 PE=4 SV=3 CANONICAL=A0A3Q1LS50-1" }, "locus": { "chromosome": "19", "start_pos": 53643765, "end_pos": 53603424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086695.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086695.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063152.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063152.3" } ] } }, { "isoform_ac": "F1MCV3-1", "url": "https://www.uniprot.org/uniprotkb/F1MCV3/entry", "sequence": { "sequence": "MKTSLNKELVRKKEFLVVEDLDMTLVIIFPDTCFCSSCRMMGILCRGSRRVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNHGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 441, "header": "tr|F1MCV3-1|A0A3Q1LS50_BOVIN Computationally mapped isoform of Cytohesin 1 OS=Bos taurus OX=9913 GN=CYTH1 PE=4 SV=5 CANONICAL=A0A3Q1LS50-1" }, "locus": { "chromosome": "19", "start_pos": 53643765, "end_pos": 53579659, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008751.8", "url": "https://www.ensembl.org/id/ENSBTAT00000008751.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008751.8", "url": "https://www.ensembl.org/id/ENSBTAP00000008751.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LS50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LS50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LS50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LS50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LS50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LS50-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 454, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LS50-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LS50" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 433, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS50" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 299, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LSB5-1", "uniprot_ac": "A0A3Q1LSB5", "uniprot_id": "A0A3Q1LSB5_BOVIN", "mass": { "chemical_mass": 90488.0, "monoisotopic_mass": 90488.0 }, "refseq": {}, "gene_names": [ { "name": "RXFP1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5" } ] } ], "protein_names": [ { "name": "Relaxin receptor 1", "type": "recommended", "evidence": [ { "id": "A0A3Q1LSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5/entry#names_and_taxonomy" } ] }, { "name": "Relaxin family peptide receptor 1", "type": "synonym", "evidence": [ { "id": "A0A3Q1LSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RVW8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVW8#function" }, { "database": "UniProtKB", "id": "ARBA00053503", "url": "https://www.uniprot.org/uniprotkb/ARBA00053503#function" }, { "database": "UniProtKB", "id": "A0A3Q1LSB5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSB5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RXFP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5", "locus": { "chromosome": "17", "start_pos": 40347518, "end_pos": 40475274, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010306", "url": "https://www.ensembl.org/id/ENSBTAG00000010306" } ] } } ], "crossref": [ { "id": "A0A3Q1LSB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LSB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010306", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010306", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15965", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15965", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532277", "url": "https://www.ncbi.nlm.nih.gov/gene/532277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LLG8", "url": "https://www.orthodb.org/?gene=A0A3Q1LLG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSB5", "url": "https://www.orthodb.org/?gene=A0A3Q1LSB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LWP1", "url": "https://www.orthodb.org/?gene=A0A3Q1LWP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M612", "url": "https://www.orthodb.org/?gene=A0A3Q1M612", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24372:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LLG8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSB5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M612", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M612", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M612-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M612-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVW8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVW8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJU7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSRPVFLYILIFGKYFAPGRAQNAPCDLGYFPCGNTTKCLPQQLQCNGVDDCENHVDEDNCGDINGWSTQFDRYYGNNYKMTSLYPSIVAETSECYFCFFLFIPLLFLVPHHPFSLLHPLYSVVGSPPMQCICQGLELECDEINLRAVPSVSSNVTFMSLRRNLIRKLPPNVFKRYHGLQTLCLQNNKIRSVSVYAFRGLYSLTKLYLSHNRITLLKPGVFEDLHRLEWLIIEDNHLNRISPLTFYGLNSLILLVLMNNVLTRLPDKSLCQHMPRLHWLDFEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLSENTFAPLQKLDELDLGSNKIENLSPHIFKDLKELSQLNLSYNPIQTIQANQFDNLIKLKSLSLEGIEISNIQQRMFRPLMNLSYIYFKRFQYCGYAPHVRICKPNTDGLSSLEDLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMESIHCQLLGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPGKCRTITVLILIWIIGVIVAFIPLSNKDFFKNYYGTNGVCFPLHSEDAESTGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSIHQSAITANEIRNQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPMQEMPSELMEPVLFADSSELSLISQSTKLNSYS", "length": 786, "header": "tr|A0A3Q1LSB5-1|A0A3Q1LSB5_BOVIN Isoform 1 of Relaxin receptor 1 OS=Bos taurus OX=9913 GN=RXFP1 PE=4 SV=2 CANONICAL=A0A3Q1LSB5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLG8/entry", "sequence": { "sequence": "MTSRPVFLYILIFGKYFAPGRAQNAPCDLGYFPCGNTTKCLPQQLQCNGVDDCENHVDEDNCGDINGWSTQFDRYYGNNYKMTSLYPSIVAETSECLVGSPPMQCICQGLELECDEINLRAVPSVSSNVTFMSLRRNLIRKLPPNVFKRYHGLQTLYLSHNRITLLKPGVFEDLHRLEWLVLMNNVLTRLPDKSLCQHMPRLHWLDFEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLSENTFAPLQKLDELDLGSNKIENLSPHIFKDLKELSQLNLSYNPIQTIQANQFDNLIKLKSLSLEGIEISNIQQRMFRPLMNLSYIYFKRFQYCGYAPHVRICKPNTDGLSSLEDLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMESIHCQLLGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPGKCRTITVLILIWIIGVIVAFIPLSNKDFFKNYYGTNGVCFPLHSEDAESTGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSIHQSAITANEIRNQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPMQEMPSELMEPVLFADSSELSLISQSTKLNSYS", "length": 711, "header": "tr|A0A3Q1LLG8-1|A0A3Q1LSB5_BOVIN Computationally mapped isoform of Relaxin receptor 1 OS=Bos taurus OX=9913 GN=RXFP1 PE=4 SV=2 CANONICAL=A0A3Q1LSB5-1" }, "locus": { "chromosome": "17", "start_pos": 40475140, "end_pos": 40348237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066913.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066913.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060609.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060609.2" } ] } }, { "isoform_ac": "A0A3Q1LSB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5/entry", "sequence": { "sequence": "MTSRPVFLYILIFGKYFAPGRAQNAPCDLGYFPCGNTTKCLPQQLQCNGVDDCENHVDEDNCGDINGWSTQFDRYYGNNYKMTSLYPSIVAETSECYFCFFLFIPLLFLVPHHPFSLLHPLYSVVGSPPMQCICQGLELECDEINLRAVPSVSSNVTFMSLRRNLIRKLPPNVFKRYHGLQTLCLQNNKIRSVSVYAFRGLYSLTKLYLSHNRITLLKPGVFEDLHRLEWLIIEDNHLNRISPLTFYGLNSLILLVLMNNVLTRLPDKSLCQHMPRLHWLDFEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLSENTFAPLQKLDELDLGSNKIENLSPHIFKDLKELSQLNLSYNPIQTIQANQFDNLIKLKSLSLEGIEISNIQQRMFRPLMNLSYIYFKRFQYCGYAPHVRICKPNTDGLSSLEDLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMESIHCQLLGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPGKCRTITVLILIWIIGVIVAFIPLSNKDFFKNYYGTNGVCFPLHSEDAESTGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSIHQSAITANEIRNQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPMQEMPSELMEPVLFADSSELSLISQSTKLNSYS", "length": 786, "header": "tr|A0A3Q1LSB5-1|A0A3Q1LSB5_BOVIN Isoform 1 of Relaxin receptor 1 OS=Bos taurus OX=9913 GN=RXFP1 PE=4 SV=2 CANONICAL=A0A3Q1LSB5-1" }, "locus": { "chromosome": "17", "start_pos": 40475140, "end_pos": 40348237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087324.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087324.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063235.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063235.2" } ] } }, { "isoform_ac": "A0A3Q1LWP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWP1/entry", "sequence": { "sequence": "MTSRPVFLYILIFGKYFAPGRAQNAPCDLGYFPCGNTTKCLPQQLQCNGVDDCENHVDEDNCGDINGWSTQFDRYYGNNYKMTSLYPSIVAETSECLVGSPPMQCICQGLELECDEINLRAVPSVSSNVTFMSLRRNLIRKLPPNVFKRYHGLQTLCLQNNKIRSVSVYAFRGLYSLTKLYLSHNRITLLKPGVFEDLHRLEWLVLMNNVLTRLPDKSLCQHMPRLHWLDFEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLSENTFAPLQKLDEFNLSYNPIQTIQANQFDNLIKLKSLSLEGIEISNIQQRMFRPLMNLSYIYFKRFQYCGYAPHVRICKPNTDGLSSLEDLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMESIHCQLLGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPGKCRTITVLILIWIIGVIVAFIPLSNKDFFKNYYGTNGVCFPLHSEDAESTGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSIHQSAITANEIRNQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPMQEMPSELMEPVLFADSSELSLISQSTKLNSYS", "length": 711, "header": "tr|A0A3Q1LWP1-1|A0A3Q1LWP1_BOVIN Computationally mapped isoform of Relaxin family peptide receptor 1 OS=Bos taurus OX=9913 GN=RXFP1 PE=4 SV=2 CANONICAL=A0A3Q1LSB5-1" }, "locus": { "chromosome": "17", "start_pos": 40475140, "end_pos": 40348237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068723.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068723.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061857.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061857.2" } ] } }, { "isoform_ac": "A0A3Q1M612-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M612/entry", "sequence": { "sequence": "MTSRPVFLYILIFGKYFAPGRAQNAPCDLGYFPCGNTTKCLPQQLQCNGVDDCENHVDEDNCGDINGWSTQFDRYYGNNYKMTSLYPSIVAETSECLVGSPPMQCICQGLELECDEINLRAVPSVSSNVTFMSLRRNLIRKLPPNVFKRYHGLQTLYLSHNRITLLKPGVFEDLHRLEWLIIEDNHLNRISPLTFYGLNSLILLVLMNNVLTRLPDKSLCQHMPRLHWLDFEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLSENTFAPLQKLDELDLGSNKIENLSPHIFKDLKELSQLNLSYNPIQTIQANQFDNLIKLKSLSLEGIEISNIQQRMFRPLMNLSYIYFKRFQYCGYAPHVRICKPNTDGLSSLEDLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMESIHCQLLGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPGKCRTITVLILIWIIGVIVAFIPLSNKDFFKNYYGTNGVCFPLHSEDAESTGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSIHQSAITANEIRNQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPMQEMPSELMEPVLFADSSELSLISQSTKLNSYS", "length": 735, "header": "tr|A0A3Q1M612-1|A0A3Q1LSB5_BOVIN Computationally mapped isoform of Relaxin receptor 1 OS=Bos taurus OX=9913 GN=RXFP1 PE=4 SV=1 CANONICAL=A0A3Q1LSB5-1" }, "locus": { "chromosome": "17", "start_pos": 40475140, "end_pos": 40348237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079234.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079234.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063721.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063721.1" } ] } }, { "isoform_ac": "A0AAA9RVW8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVW8/entry", "sequence": { "sequence": "MTSRPVFLYILIFGKYFAPGRAQNAPCDLGYFPCGNTTKCLPQQLQCNGVDDCENHVDEDNCVVGSPPMQCICQGLELECDEINLRAVPSVSSNVTFMSLRRNLIRKLPPNVFKRYHGLQTLCLQNNKIRSVSVYAFRGLYSLTKLYLSHNRITLLKPGVFEDLHRLEWLIIEDNHLNRISPLTFYGLNSLILLVLMNNVLTRLPDKSLCQHMPRLHWLDFEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLSENTFAPLQKLDELDLGSNKIENLSPHIFKDLKELSQLNLSYNPIQTIQANQFDNLIKLKSLSLEGIEISNIQQRMFRPLMNLSYIYFKRFQYCGYAPHVRICKPNTDGLSSLEDLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMESIHCQLLGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPGKCRTITVLILIWIIGVIVAFIPLSNKDFFKNYYGTNGVCFPLHSEDAESTGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSIHQSAITANEIRNQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPMQEMPSELMEPVLFADSSELSLISQSTKLNSYS", "length": 725, "header": "tr|A0AAA9RVW8-1|A0A3Q1LSB5_BOVIN Computationally mapped isoform of Relaxin receptor 1 OS=Bos taurus OX=9913 GN=RXFP1 PE=4 SV=1 CANONICAL=A0A3Q1LSB5-1" }, "locus": { "chromosome": "17", "start_pos": 40475140, "end_pos": 40348237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101339.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101339.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075155.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075155.1" } ] } }, { "isoform_ac": "A0AAA9TJU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJU7/entry", "sequence": { "sequence": "MTSRPVFLYILIFGKYFAPGRAQNAPCDLGYFPCGNTTKCLPQQLQCNGVDDCENHVDEDNCGDINGWSTQFDRYYGNNYKMTSLYPSIVAETSECLVGSPPMQCICQGLELECDEINLRAVPSVSSNVTFMSLRRNLIRKLPPNVFKRYHGLQTLCLQNNKIRSVSVYAFRGLYSLTKLYLSHNRITLLKPGVFEDLHRLEWLIIEDNHLNRISPLTFYGLNSLILLVLMNNVLTRLPDKSLCQHMPRLHWLDFEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLSENTFAPLQKLDEFSLEGIEISNIQQRMFRPLMNLSYIYFKRFQYCGYAPHVRICKPNTDGLSSLEDLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLHAMSIISLCCADCLMGIYLFVIGAFDLKFRGEYNKHAQLWMESIHCQLLGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCLRPGKCRTITVLILIWIIGVIVAFIPLSNKDFFKNYYGTNGVCFPLHSEDAESTGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSIHQSAITANEIRNQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHQFWYNYRQRRSIDSKGSQKTYAPSFIWVEMWPMQEMPSELMEPVLFADSSELSLISQSTKLNSYS", "length": 711, "header": "tr|A0AAA9TJU7-1|A0A3Q1LSB5_BOVIN Computationally mapped isoform of Relaxin receptor 1 OS=Bos taurus OX=9913 GN=RXFP1 PE=4 SV=1 CANONICAL=A0A3Q1LSB5-1" }, "locus": { "chromosome": "17", "start_pos": 40475140, "end_pos": 40348237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122440.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122440.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097199.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097199.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSB5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSB5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5" } ], "pmid": "" }, { "name": "hormone binding", "id": "GO:0042562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042562", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSB5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSB5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LSB5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 786, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LSB5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LSB5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 450, "end_pos": 709, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 396, "end_pos": 398 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LN99-1", "uniprot_ac": "A0A3Q1LN99", "uniprot_id": "A0A3Q1LN99_BOVIN", "mass": { "chemical_mass": 5859.0, "monoisotopic_mass": 5859.0 }, "refseq": { "ac": "XP_059741329", "name": "ATP synthase subunit 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Annotation" ] }, { "id": "IPR006721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:132345003", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132345003", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQNDRTA", "url": "https://omabrowser.org/oma/group/NQNDRTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12448", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12448", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12448:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12448:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059741329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741329", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEYWQQIGLSYLRYSQICAKAMRDTLKTEFKANAEKTSGSSIKVVKVKKE", "length": 51, "header": "tr|A0A3Q1LN99-1|A0A3Q1LN99_BOVIN Isoform 1 of ATP synthase subunit epsilon, mitochondrial OS=Bos taurus OX=9913 GN=LOC132345003 PE=3 SV=1 CANONICAL=A0A3Q1LN99-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LN99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN99/entry", "sequence": { "sequence": "MAEYWQQIGLSYLRYSQICAKAMRDTLKTEFKANAEKTSGSSIKVVKVKKE", "length": 51, "header": "tr|A0A3Q1LN99-1|A0A3Q1LN99_BOVIN Isoform 1 of ATP synthase subunit epsilon, mitochondrial OS=Bos taurus OX=9913 GN=LOC132345003 PE=3 SV=1 CANONICAL=A0A3Q1LN99-1" }, "locus": { "chromosome": "3", "start_pos": 63368543, "end_pos": 63368391, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087248.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087248.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058270.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058270.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:132345003", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132345003", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P29418-1", "protein_name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "gene_name": "Atp5f1e", "tax_id": 10116, "organism": "Rattus norvegicus", 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"categories": [ "Gene Expression" ] }, { "id": "cd14377", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14377", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ENGRICC", "url": "https://omabrowser.org/oma/group/ENGRICC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10621", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10621", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10621:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10621:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "67804", "url": "https://www.rhea-db.org/rhea/67804", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85907", "url": "https://www.rhea-db.org/rhea/85907", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85911", "url": "https://www.rhea-db.org/rhea/85911", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LND7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVTLKTLQQQTFKIDIDPDETVRALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALKEYKIDEKNFMVVMVTKPKAPAPAPTSAPTSTPASVTPAPTTASSEPAPASAAKQEKPAERPVETPVATTPTSTDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGDEREQVIAALRASFNNPDRAVVYLLISGGHPLEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYIQVTPQEKEAIERLKASGFPEGLVIHAYFACEKENLAANFLLQQNFDED", "length": 334, "header": "tr|A0A3Q1LND7-1|A0A3Q1LND7_BOVIN Isoform 1 of UV excision repair protein RAD23 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0A3Q1LND7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LND7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7/entry", "sequence": { "sequence": "MLVTLKTLQQQTFKIDIDPDETVRALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALKEYKIDEKNFMVVMVTKPKAPAPAPTSAPTSTPASVTPAPTTASSEPAPASAAKQEKPAERPVETPVATTPTSTDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGDEREQVIAALRASFNNPDRAVVYLLISGGHPLEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYIQVTPQEKEAIERLKASGFPEGLVIHAYFACEKENLAANFLLQQNFDED", "length": 334, "header": "tr|A0A3Q1LND7-1|A0A3Q1LND7_BOVIN Isoform 1 of UV excision repair protein RAD23 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0A3Q1LND7-1" }, "locus": { "chromosome": "2", "start_pos": 84020154, "end_pos": 84018941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013153.5", "url": "https://www.ensembl.org/id/ENSBTAT00000013153.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058482.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058482.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 100, "start_aa": "Thr", "end_pos": 100, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr100", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 85, "start_aa": "Thr", "end_pos": 85, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr85", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8PYT0-1", "protein_name": "UV excision repair protein RAD23", "gene_name": "rad23b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQITLKTLQQQTFKIDIDAEETVKALKEKIENEKGKDGFPVAGQKLIYAGKILSDDTALKEYKIDEKNFVVVMVTKPKSASAPAPPSSSSSSSSSTTASASAAPSAAPVSESPSEEEKKPSEEKPSSDPAPATTPVSSGSLPNANIFEEATSALVTGQSYENMVTEIMLMGYERDRVVAALRASFNNPDRAVEYLLTGIPAEGEGSVVGAVDAVSPSGSTPASAPAPAISTGLSSPSSTAPAQPSSASGANPLEFLRNQPQFLQMRQIIQQNPSLLPALLQQIGRENPQLLQQISSHQEQFIQMLNEPVQEAGQGGGAGGVAEAGGGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDDD", "length": 381 }, "evidence": [ { "id": "A0A3Q1LND7", "url": "https://omabrowser.org/oma/group/A0A3Q1LND7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" }, { "name": "proteasome binding", "id": "GO:0070628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LND7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LND7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "67804", "name": "", "equation": "N(6)-methyl-L-lysyl(20)-[histone H4] + 2-oxoglutarate + O2 = L-lysyl(20)-[histone H4] + formaldehyde + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1N542-1", "F1MBS5-1", "A3KMV2-1", "A0A3Q1LWW0-1", "Q29RK4-1" ], "evidence": [ { "id": "67804", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67804" } ] }, { "id": "85907", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + 2-oxoglutarate + O2 = N(6)-methyl-L-lysyl(20)-[histone H4] + formaldehyde + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MBS5-1", "A3KMV2-1", "Q29RK4-1" ], "evidence": [ { "id": "85907", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85907" } ] }, { "id": "85911", "name": "", "equation": "N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 2-oxoglutarate + O2 = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + formaldehyde + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A3KMV2-1", "Q29RK4-1" ], "evidence": [ { "id": "85911", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85911" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LWW0", "gene_name": "PHF8", "activity": [ { "ec_number": "1.14.11.65", "activity": "N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "A0A3Q1LWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWW0" } ] }, { "ec_number": "1.14.11.65", "activity": "", "evidence": [ { "id": "A0A3Q1LWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWW0" } ] } ] }, { "uniprot_ac": "A3KMV2", "gene_name": "RAD23A", "activity": [ { "ec_number": "1.14.11.-", "activity": "", "evidence": [ { "id": "A3KMV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KMV2" } ] } ] }, { "uniprot_ac": "F1MBS5", "gene_name": "KDM1A", "activity": [ { "ec_number": "1.14.11.65", "activity": 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"length": 1560, "header": "tr|A0A3Q1LNE2-1|A0A3Q1LNE2_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 11 OS=Bos taurus OX=9913 GN=ARHGEF11 PE=4 SV=2 CANONICAL=A0A3Q1LNE2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2/entry", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETTGLVQRCVIIQRDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGPQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPRPLQDPEFQKHATQILRNMLRQEEKELQRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGGLVDILPVYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLVNRNSVLSDAGLDSPRTSPVTMARLAQRHRRQGSDAPVPPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIIFQDFEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSSEDVRAALCEAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLELDGDPLHERQVAEKQLAALGDILSKYEEDRSGPMGFALNTYMSHAGIRLRETRPPNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKDKDALEDKKRNPILKYIGKPKTSSQSTFYIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESNSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPNLGFCTDPLLPNLLEDDLGQLSDLEPEPDAQNWQHTVGKDVVARLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMRKLREEGPIIKEVSDLMLARFDGPAREELQEVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDTTSLERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLVRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRLPGAAPTPIHPPPPGPQEPADQSPPPSRAGPDDSEVFRGEAEPGAAPGGMGCQQRIQGKPLALLADAEQEGSVEEEELGALPHSSASLDSKHRGSRTRDPILLPLPGPLFIEGLADAALEDVENLRHLILWSLLPGHPTDPRAAGEPEDDLTPTPSFISITSHPWDPGSPGRAPAGTEGDTAPLLGPEWSQPGQEDTTLRSLEQLPPRTRNSGIWESSELDKSPEEEASSTEGTGSYKVVRKAEVAGSKVVPALPESGQAGPEPPEAEGGAKAAGNCFYVSMPAGPPDSSTDPSGAHTSPSQPDGLPAWQTEPQPPLQGGHGDQKHPSRSPPSLALRDVGMIFRTIEQLTLKLNRLKDMELAHRELLRSLRSQSSGGTTPVGSFHTEAARWIESSLSPPAKEPPASDSTDSRELGPCPEDGPTPLEDSTADTAASPGP", "length": 1560, "header": "tr|A0A3Q1LNE2-1|A0A3Q1LNE2_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 11 OS=Bos taurus OX=9913 GN=ARHGEF11 PE=4 SV=2 CANONICAL=A0A3Q1LNE2-1" }, "locus": { "chromosome": "3", "start_pos": 13922857, "end_pos": 13807814, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077218.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077218.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058487.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058487.2" } ] } }, { "isoform_ac": "A0A3Q1MQC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQC6/entry", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETTGLVQRCVIIQRDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGPQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPRPLQDPEFQKHATQILRNMLRQEEKELQDILPVYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLVNRNSVLSDAGLDSPRTSPVTMARLAQRHRRQGSDAPVPPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIIFQDFEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSSEDVRAALCEAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLELDGDPLHERQVAEKQLAALGDILSKYEEDRSGPMGFALNTYMSHAGIRLRETRPPNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKDKDALEDKKRNPILKYIGKPKTSSQSTFYIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESNSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPNLGFCTDPLLPNLLEDDLGQLSDLEPEPDAQNWQHTVGKDVVARLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMRKLREEGPIIKEVSDLMLARFDGPAREELQEVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDTTSLERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLVRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRLPGAAPTPIHPPPPGPQEPADQSPPPSRAGPDDSEVFRGEAEPGAAPGGMGCQQRIQGKPLALLADAEQEGSVEEEELGALPHSSASLDSKHRGSRTRDPILLPLPGPLFIEGLADAALEDVENLRHLILWSLLPGHPTDPRAAGEPEDDLTPTPSFISITSHPWDPGSPGRAPAGTEGDTAPLLGPEWSQPGQEDTTLRSLEQLPPRTRNSGIWESSELDKSPEEEASSTEGTGSYKVVRKAEVAGSKVVPALPESGQAGPEPPEAEGGAKAAGNCFYVSMPAGPPDSSTDPSGAHTSPSQPDGLPAWQTEPQPPLQGGHGDQKHPSRSPPSLALRDVGMIFRTIEQLTLKLNRLKDMELAHRELLRSLRSQSSGGTTPVGSFHTEAARWIESSLSPPAKEPPASDSTDSRELGPCPEDGPTPLEDSTADTAASPGP", "length": 1520, "header": "tr|A0A3Q1MQC6-1|A0A3Q1LNE2_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 11 OS=Bos taurus OX=9913 GN=ARHGEF11 PE=4 SV=3 CANONICAL=A0A3Q1LNE2-1" }, "locus": { "chromosome": "3", "start_pos": 13922857, "end_pos": 13807814, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066742.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066742.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074205.3", "url": "https://www.ensembl.org/id/ENSBTAP00000074205.3" } ] } }, { "isoform_ac": "F1MZW2-1", "url": "https://www.uniprot.org/uniprotkb/F1MZW2/entry", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETTGLVQRCVIIQRDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGPQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPRPLQDPEFQKHATQILRNMLRQEEKELQRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGGLVDILPVYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLVNRNSVLSDAGLDSPRTSPVTMARLAQRHRRQGSDAPVPPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIIFQDFEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSSEDVRAALCEAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLELDGDPLHERQVAEKQLAALGDILSKYEEDRSGPMGFALNTYMSHAGIRLRETRPPNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKDKDALEDKKRNPILKYIGKPKTSSQSIKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESNSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPNLGFCTDPLLPNLLEDDLGQLSDLEPEPDAQNWQHTVGKDVVARLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMRKLREEGPIIKEVSDLMLARFDGPAREELQEVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDTTSLERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLVRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRLPGAAPTPIHPPPPGPQEPADQSPPPSRAGPDDSEVFRGEAEPGAAPGGMGCQQRIQGKPLALLADAEQEGSVEEEELGALPHSSASLDSKHRGSRTRDPILLPLPGPLFIEGLADAALEDVENLRHLILWSLLPGHPTDPRAAGEPEDDLTPTPSFISITSHPWDPGSPGRAPAGTEGDTAPLLGPEWSQPGQEDTTLRSLEQLPPRTRNSGIWESSELDKSPEEEASSTEGTGSYKVVRKAEVAGSKVVPALPESGQAGPEPPEAEGGAKAAGNCFYVSMPAGPPDSSTDPSGAHTSPSQPDGLPAWQTEPQPPLQGGHGDQKHPSRSPPSLALRDVGMIFRTIEQLTLKLNRLKDMELAHRELLRSLRSQSSGGTTPVGSFHTEAARWIESSLSPPAKEPPASDSTDSRELGPCPEDGPTPLEDSTADTAASPGP", "length": 1550, "header": "tr|F1MZW2-1|A0A3Q1LNE2_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 11 OS=Bos taurus OX=9913 GN=ARHGEF11 PE=4 SV=3 CANONICAL=A0A3Q1LNE2-1" }, "locus": { "chromosome": "3", "start_pos": 13922857, "end_pos": 13807814, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016407.8", "url": "https://www.ensembl.org/id/ENSBTAT00000016407.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016407.7", "url": "https://www.ensembl.org/id/ENSBTAP00000016407.7" } ] } }, { "isoform_ac": "G3N0T5-1", "url": "https://www.uniprot.org/uniprotkb/G3N0T5/entry", "sequence": { "sequence": "MSVRLPQSIDRLSSLSLGDSAPERKSPSHHRQPSDTSETTGLVQRCVIIQRDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSVGVSGPQQDPAPAGAPRVTPVVPPPPPPPPLPPPQRITGPRPLQDPEFQKHATQILRNMLRQEEKELQRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGGLVDILPVYGDTSQRSSEGRLSLDSQEGDSGLDSGTERFPSLSESLVNRNSVLSDAGLDSPRTSPVTMARLAQRHRRQGSDAPVPPSSDQGVDQSPKPLIIGPEEDYDPGYFNNESDIIFQDFEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQTNPKDSRSLGKDIWNIFLEKNAPLRVKVPEMLQAEIDLRLRSSEDVRAALCEAQEAAMPEIQEQIHDYRTKRTLGLGSLYGENDLLELDGDPLHERQVAEKQLAALGDILSKYEEDRSGPMGFALNTYMSHAGIRLRETRPPNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKDKDALEDKKRNPILKYIGKPKTSSQSTFYIPLSPVEVKPGNVRNIIQHFENNQQYDAPEPGTQRLSTGSFPEDLLESNSSRSEIRLGRSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEAARLHQSASSSASSLSTRSLENPTPPFTPKMGRRSIESPNLGFCTDPLLPNLLEDDLGQLSDLEPEPDAQNWQHTVGKDVVARLSQREIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEGLLPREELARLFPNLPELIEIHNSWCEAMRKLREEGPIIKEVSDLMLARFDGPAREELQEVAAQFCSYQSIALELIKTRQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLENIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLDTTSLERASNPLAAEFKSLDLTTRKMIHEGPLTWRISKDKTLDLHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTFSPVLKLNAVLVRSVATDKRAFFIICTSELGPPQIYELVALTSSDKNTWMELLEEAVRNATRLPGAAPTPIHPPPPGPQEPADQSPPPSRAGPDDSEVFRGEAEPGAAPGGMGCQQRIQGKPLALLADAEQEGSVEEEELGALPHSSASLDSKHRGSRTRDPILLPLPGPLFIEGLADAALEDVENLRHLILWSLLPGHPTDPRAAGEPEDDLTPTPSFISITSHPWDPGSPGRAPAGTEGDTAPLLGPEWSQPGQEDTTLRSLEQLPPRTRNSGIWESSELDKSPEEEASSTEGTGSYKVVRKGNCFYVSMPAGPPDSSTDPSGAHTSPSQPDGLPAWQTEPQPPLQGGHGDQKHPSRSPPSLALRDVGMIFRTIEQLTLKLNRLKDMELAHRELLRSLRSQSSGGTTPVGSFHTEAARWIESSLSPPAKEPPASDSTDSRELGPCPEDGPTPLEDSTADTAASPGP", "length": 1528, "header": "tr|G3N0T5-1|A0A3Q1LNE2_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 11 OS=Bos taurus OX=9913 GN=ARHGEF11 PE=4 SV=3 CANONICAL=A0A3Q1LNE2-1" }, "locus": { "chromosome": "3", "start_pos": 13922857, "end_pos": 13807814, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064318.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064318.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055453.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055453.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1129, "start_aa": "Thr", "end_pos": 1129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1129", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1276, "start_aa": "Thr", "end_pos": 1276, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1276", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-BTA-416572", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416572", "resource": "Reactome", "description": "Sema4D induced cell migration and growth-cone collapse" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-BTA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNE2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNE2" } ], "pmid": "" }, 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340, "header": "tr|A0A3Q1LNH5-1|A0A3Q1LNH5_BOVIN Isoform 1 of Transmembrane protein 123 OS=Bos taurus OX=9913 GN=TMEM123 PE=3 SV=2 CANONICAL=A0A3Q1LNH5-1" }, "locus": { "chromosome": "15", "start_pos": 6303214, "end_pos": 6225324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068225.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068225.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058525.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058525.2" } ] } }, { "isoform_ac": "A0A3Q1LSG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSG1/entry", "sequence": { "sequence": "MGLGARGFLTLLALGVVLGVALLKVFTDSADPEGSVSQKNLMSVENSNDNQQGTADNDSKSPENSKDNQGGSSSQNNPQSERNSNGNNQGGPPKQQNLQSAGNSNDNQGGSPNQNNDQSKEKSDGHQGGSPNQNNGQSEEKPGGQKEDPQGHPGHRHEPPNVSMKTSTASVSPVSKNVTTTTLKDIGKSSSETKDSPASNHGTSTTSTPFATSKMITPVVSTNMTSTTLRSTPKITNVSQNTSQVSVSTVPTAHNSSSSVTVTTTIISKENKGSKFDTGSFVGGIVLTLGVLSFLYIGCKVYYSRRGIRYRTIDEHDAII", "length": 320, "header": "tr|A0A3Q1LSG1-1|A0A3Q1LSG1_BOVIN Computationally mapped isoform of Transmembrane protein 123 OS=Bos taurus OX=9913 GN=TMEM123 PE=3 SV=3 CANONICAL=A0A3Q1LNH5-1" }, "locus": { "chromosome": "15", "start_pos": 6303214, "end_pos": 6225324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075849.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075849.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060179.3", "url": "https://www.ensembl.org/id/ENSBTAP00000060179.3" } ] } }, { "isoform_ac": "A0A3Q1M582-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M582/entry", "sequence": { "sequence": "MGLGARGFLTLLALGVVLGVALLKVFTDSADPEGSVSQKNLMSVENSNDNQQGTADNDSKSPENSKDNQGGSSSQNNPQSERNSNGNNQGGSPNQNNGQSEEKPGGQKEGSPKQNNPQSGGNSNGNNQGGSPNQNNDQSKEKSDGHQGGSPNQNNGQSEEKPGGQKEDPQGHPGHRHEPPNVSMKTSTASVSPVSKNVTTTTLKDIGKSSSETKDSPASNHGTSTTSTPFATSKMITPVVSTNMTSTTLRSTPKITNVSQNTSQVSVSTVPTAHNSSSSVTVTTTIISKENKGSKFDTGSFVGGIVLTLGVLSFLYIGCKVYYSRRGIRYRTIDEHDAII", "length": 340, "header": "tr|A0A3Q1M582-1|A0A3Q1M582_BOVIN Computationally mapped isoform of Transmembrane protein 123 OS=Bos taurus OX=9913 GN=TMEM123 PE=3 SV=2 CANONICAL=A0A3Q1LNH5-1" }, "locus": { "chromosome": "15", "start_pos": 6303214, "end_pos": 6225324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075133.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075133.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065047.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065047.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNH5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNH5" } ], "pmid": "" } ] } ] }, 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"url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0H5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM53", "url": "https://www.uniprot.org/uniprotkb/E1BM53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BM53-1", "url": "https://www.uniprot.org/uniprotkb/E1BM53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPAAPGSVIVPDWHESAQGKEYLACILRKSRRRVFGLLERPVLPPPVAIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASDRVVMFRFEFWDCGESALKKFEHMLPVSGQACKENADAFLFLFSFTDRASFEDLPGQLARVAGEAPGVVRMVIGSKFDQYVHTDVPERDLAAFRQAWPLPLLRVKSVPGRRLADGRTLDGRAGLADVAHVLNGLAEQLWHQDQVAAGLLPAPEACPGPGVVGS", "length": 267, "header": "tr|A0A3Q1LNI2-1|A0A3Q1LNI2_BOVIN Isoform 1 of Ciliogenesis and planar polarity effector 2 OS=Bos taurus OX=9913 GN=CPLANE2 PE=3 SV=2 CANONICAL=A0A3Q1LNI2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2/entry", "sequence": { "sequence": "MAGPAAPGSVIVPDWHESAQGKEYLACILRKSRRRVFGLLERPVLPPPVAIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASDRVVMFRFEFWDCGESALKKFEHMLPVSGQACKENADAFLFLFSFTDRASFEDLPGQLARVAGEAPGVVRMVIGSKFDQYVHTDVPERDLAAFRQAWPLPLLRVKSVPGRRLADGRTLDGRAGLADVAHVLNGLAEQLWHQDQVAAGLLPAPEACPGPGVVGS", "length": 267, "header": "tr|A0A3Q1LNI2-1|A0A3Q1LNI2_BOVIN Isoform 1 of Ciliogenesis and planar polarity effector 2 OS=Bos taurus OX=9913 GN=CPLANE2 PE=3 SV=2 CANONICAL=A0A3Q1LNI2-1" }, "locus": { "chromosome": "2", "start_pos": 135881202, "end_pos": 135877622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074971.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074971.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058373.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058373.2" } ] } }, { "isoform_ac": "A0AAA9U0H5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H5/entry", "sequence": { "sequence": "MAGPAAPGSVIVPDWHESAQGKEYLACILRKSRRRVFGLLERPVLPPPVAIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASDRVVMFRFEFWDCGESALKKFEHMLPACKENADAFLFLFSFTDRASFEDLPGQLARVAGEAPGVVRMVIGSKFDQYVHTDVPERDLAAFRQKCGFPPRTGHGACQGGWRPGKALSSWSSAQGGGHTALQGSGLRASGCPPASSVAPGAGLLKTE", "length": 258, "header": "tr|A0AAA9U0H5-1|A0A3Q1LNI2_BOVIN Computationally mapped isoform of Ciliogenesis and planar polarity effector 2 OS=Bos taurus OX=9913 GN=CPLANE2 PE=3 SV=1 CANONICAL=A0A3Q1LNI2-1" }, "locus": { "chromosome": "2", "start_pos": 135881453, "end_pos": 135877622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121881.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121881.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103431.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103431.1" } ] } }, { "isoform_ac": "E1BM53-1", "url": "https://www.uniprot.org/uniprotkb/E1BM53/entry", "sequence": { "sequence": "MAGPAAPGSVIVPDWHESAQGKEYLACILRKSRRRVFGLLERPVLPPPVAIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASDRVVMFRFEFWDCGESALKKFEHMLPACKENADAFLFLFSFTDRASFEDLPGQLARVAGEAPGVVRMVIGSKYPPGAPALLRGHVWRGAERGSGGLPVPRGGVRPRGLPRGCTRASRRPGCGGRGTGRRLALTGKPRVSQTGSLTRLQIRPVRAHGRARAGPRGLPAGLATAPAAGEERAGAAAGGRTHAGRPGRAGRRRPRAQRPGGAAVAPGPGGSWPAPRPRGLSRPRGGGLVSGHSPPAGDPEQDLGPALGQKCGFPPRTGHGACQGGWRPGKALSSWSSAQGGGHTALQGSGLRASGCPPASSVAPGAGLLKTEALYAQGPRAQVSPPAPPAASQRVTGERVPQLGPGSQAPSVRSRC", "length": 467, "header": "tr|E1BM53-1|E1BM53_BOVIN Computationally mapped isoform of Ciliogenesis and planar polarity effector 2 OS=Bos taurus OX=9913 GN=CPLANE2 PE=3 SV=2 CANONICAL=A0A3Q1LNI2-1" }, "locus": { "chromosome": "2", "start_pos": 135881585, "end_pos": 135877622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018903.8", "url": "https://www.ensembl.org/id/ENSBTAT00000018903.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018903.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018903.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LNI2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 267, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LNI2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNI2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LNI4-1", "uniprot_ac": "A0A3Q1LNI4", "uniprot_id": "A0A3Q1LNI4_BOVIN", "mass": { "chemical_mass": 138221.0, "monoisotopic_mass": 138221.0 }, "refseq": { "ac": "XP_005202324", "name": "protein ITPRID2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202324" }, "gene_names": [ { "name": "ITPRID2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4" } ] }, { "name": "ITPRID2", "type": "synonym", "evidence": [ { "id": "XP_005202324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202324" } ] }, { "name": "SSFA2", "type": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LNI4", "locus": { "chromosome": "2", "start_pos": 14654230, "end_pos": 14751368, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000937", "url": "https://www.ensembl.org/id/ENSBTAG00000000937" } ] } } ], "crossref": [ { "id": "A0A3Q1LNI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000937", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538826", "url": "https://www.ncbi.nlm.nih.gov/gene/538826", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538826", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538826", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LNI4", "url": "https://www.orthodb.org/?gene=A0A3Q1LNI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BET5", "url": "https://www.orthodb.org/?gene=E1BET5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17469", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17469", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17469:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17469:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14723", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14723", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005202324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005202324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNI4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3V8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BET5", "url": "https://www.uniprot.org/uniprotkb/E1BET5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BET5-1", "url": "https://www.uniprot.org/uniprotkb/E1BET5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRPLVASAEAEEELEWQVASRRRKAWAKCRGSWQASETEDLSTEATTQDEDEDEDEDDLSGTKLPAAAGRGNVPNEKIAIWLKDCRTPLGASLDEQSGSTLKGVLVRNGGSFEDDLSLGAEANHLHEIDAQIDNCNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSDKETDSPPPLTRSNTANRLMKTLSKLNLCIEKTEKGEGSTPSLAVDKGKIVNISVMEESGNKNDQKSQKVVKKKESSSVLATVKEEVSGSSAALVENSDIDGLSDEANSNFNREAESGQSQETQSHENKLDEESGFLETDLGGDFNMSSHSELENSGELKNVPLCTPEKEPCAPLMIPSIRNIMAQQKDSFEMEEVQSTEGEAPHVPTTYQLGLNKSKRDQLLRTASQHSDSSGFAEDSTDCLSLNHLQVHESLQAMGSSADSCDSETTVTSFGEDLVTPTVQDQRYFNESEEESLTCPQIEREKAATVAEKRSDGQDSLLCQTVENIGHQQSTWSAGDHATEITERKEDVSPAQPVELLREASAESDVDKSSECEFVQYTTHHILKSLASIEAKCGEKGAENTTGSPSSVDRVNTALQRAQMKVCSLSNQRVGRSLIKSKDLLKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTQEEEQRLEKEVTEHDGQSSVKSTIFISPTSGKKEADAPSEVTRLEECHQRRTPACSLPAPAPVSQSTCSLHSLHSEWQERHLCEHMRTLSTHSVPSVAGAACSAFPCPLGCPYSHRHAASPYRACSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDLAAAPYSTQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERYEVDQLQSLRNSVRMELQDLELQLEERLLGLEEQLRPVHLPSAFRPSALMGMCGSRSADNLSCPSPLNVMEPVTELMREQSYLKSELGLGHGEMGFEIPPGESSESVFSQATSESSSVCSGPSHASRRTGVPPIDSVGKPKTHLVPSKKLFRASVALTPTAPSRTGSVQTPPDVESSEEAGATEETSEAVGPKSEVEEEQGKVSLLPAAEEVHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDSH", "length": 1258, "header": "tr|A0A3Q1LNI4-1|A0A3Q1LNI4_BOVIN Isoform 1 of ITPR interacting domain containing 2 OS=Bos taurus OX=9913 GN=ITPRID2 PE=4 SV=2 CANONICAL=A0A3Q1LNI4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4/entry", "sequence": { "sequence": "MDRPLVASAEAEEELEWQVASRRRKAWAKCRGSWQASETEDLSTEATTQDEDEDEDEDDLSGTKLPAAAGRGNVPNEKIAIWLKDCRTPLGASLDEQSGSTLKGVLVRNGGSFEDDLSLGAEANHLHEIDAQIDNCNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSDKETDSPPPLTRSNTANRLMKTLSKLNLCIEKTEKGEGSTPSLAVDKGKIVNISVMEESGNKNDQKSQKVVKKKESSSVLATVKEEVSGSSAALVENSDIDGLSDEANSNFNREAESGQSQETQSHENKLDEESGFLETDLGGDFNMSSHSELENSGELKNVPLCTPEKEPCAPLMIPSIRNIMAQQKDSFEMEEVQSTEGEAPHVPTTYQLGLNKSKRDQLLRTASQHSDSSGFAEDSTDCLSLNHLQVHESLQAMGSSADSCDSETTVTSFGEDLVTPTVQDQRYFNESEEESLTCPQIEREKAATVAEKRSDGQDSLLCQTVENIGHQQSTWSAGDHATEITERKEDVSPAQPVELLREASAESDVDKSSECEFVQYTTHHILKSLASIEAKCGEKGAENTTGSPSSVDRVNTALQRAQMKVCSLSNQRVGRSLIKSKDLLKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTQEEEQRLEKEVTEHDGQSSVKSTIFISPTSGKKEADAPSEVTRLEECHQRRTPACSLPAPAPVSQSTCSLHSLHSEWQERHLCEHMRTLSTHSVPSVAGAACSAFPCPLGCPYSHRHAASPYRACSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDLAAAPYSTQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERYEVDQLQSLRNSVRMELQDLELQLEERLLGLEEQLRPVHLPSAFRPSALMGMCGSRSADNLSCPSPLNVMEPVTELMREQSYLKSELGLGHGEMGFEIPPGESSESVFSQATSESSSVCSGPSHASRRTGVPPIDSVGKPKTHLVPSKKLFRASVALTPTAPSRTGSVQTPPDVESSEEAGATEETSEAVGPKSEVEEEQGKVSLLPAAEEVHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDSH", "length": 1258, "header": "tr|A0A3Q1LNI4-1|A0A3Q1LNI4_BOVIN Isoform 1 of ITPR interacting domain containing 2 OS=Bos taurus OX=9913 GN=ITPRID2 PE=4 SV=2 CANONICAL=A0A3Q1LNI4-1" }, "locus": { "chromosome": "2", "start_pos": 14690957, "end_pos": 14655980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083392.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083392.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061561.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061561.2" } ] } }, { "isoform_ac": "A0A3Q1LQJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ1/entry", "sequence": { "sequence": "MTTEDQLLRTASQHSDSSGFAEDSTDCLSLNHLQVHESLQAMGSSADSCDSETTVTSFGEDLVTPTVQDQRYFNESEEESLTCPQIEREKAATVAEKRSDGQDSLLCQTVENIGHQQSTWSAGDHATEITERKEDVSPAQPVELLREASAESDVDKSSECEFVQYTTHHILKSLASIEAKCGEKGAENTTGSPSSVDRVNTALQRAQMKVCSLSNQRVGRSLIKSKDLLKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTQEEEQRLEKEVTEHDGQSSVKSTIFISPTSGKKEADAPSEVTRLEECHQRRTPACSLPAPAPVSQSTCSLHSLHSEWQERHLCEHMRTLSTHSVPSVAGAACSAFPCPLGCPYSHRHAASPYRACSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDLAAAPYSTQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERYEVDQLQSLRNSVRMELQDLELQLEERLLGLEEQLRPVHLPSAFRPSALMGMCGSRSADNLSCPSPLNVMEPVTELMREQSYLKSELGLGHGEMGFEIPPGESSESVFSQATSESSSVCSGPSHASRRTGVPPIDSVGKPKTHLVPSKKLFRASVALTPTAPSRTGSVQTPPDVESSEEAGATEETSEAVGPKSEVEEEQGKVSLLPAAEEVHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDSH", "length": 767, "header": "tr|A0A3Q1LQJ1-1|A0A3Q1LNI4_BOVIN Computationally mapped isoform of ITPR interacting domain containing 2 OS=Bos taurus OX=9913 GN=ITPRID2 PE=4 SV=2 CANONICAL=A0A3Q1LNI4-1" }, "locus": { "chromosome": "2", "start_pos": 14675008, "end_pos": 14655980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082749.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082749.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057239.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057239.2" } ] } }, { "isoform_ac": "A0A3Q1M3V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3V8/entry", "sequence": { "sequence": "MDRPLVASAEAEEELEWQVASRRRKAWAKCRGSWQASETEDLSTEATTQDEDEDEDEDDLSGTKLPAAAGRGNVPNEKIAIWLKDCRTPLGASLDEQSGSTLKGVLVRNGGSFEDDLSLGAEANHLHEIDAQIDNCSNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSDKETDSPPPLTRSNTANRLMKTLSKLNLCIEKTEKGEGSTPSLAVDKGKIVNISVMEESGNKNDQKSQKVVKKKESSSVLATVKEEVSGSSAALVENSDIDGLSDEANSNFNREAESGQSQETQSHENKLDEESGFLETDLGGDFNMSSHSELENSGELKNVPLCTPEKEPCAPLMIPSIRNIMAQQKDSFEMEEVQSTEGEAPHVPTTYQLGLNKSKRDQLLRTASQHSDSSGFAEDSTDCLSLNHLQVHESLQAMGSSADSCDSETTVTSFGEDLVTPTVQDQRYFNESEEESLTCPQIEREKAATVAEKRSDGQDSLLCQTVENIGHQQSTWSAGDHATEITERKEDVSPAQPVELLREASAESDVDKSSECEFVQYTTHHILKSLASIEAKCGEKGAENTTGSPSSVDRVNTALQRAQMKVCSLSNQRVGRSLIKSKDLLKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTQEEEQRLEKEVTEHDGQSSVKSTIFISPTSGKKEADAPSEVTRLEECHQRRTPACSLPAPAPVSQSTCSLHSLHSEWQERHLCEHMRTLSTHSVPSVAGAACSAFPCPLGCPYSHRHAASPYRACSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDLAAAPYSTQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERYEVDQLQSLRNSVRMELQDLELQLEERLLGLEEQLRPVHLPSAFRPSALMVTELMREQSYLKSELGLGHGEMGFEIPPGESSESVFSQATSESSSVCSGPSHASRRTGVPPIDSVGKPKTHLVPSKKLFRASVALTPTAPSRTGSVQTPPDVESSEEAGATEETSEAVGPKSEVEEEQGKVSLLPAAEEVHKNVEQDELQQVIREIKESIVGEIRREIVSGLLAAVSSSKASNSKQDSH", "length": 1237, "header": "tr|A0A3Q1M3V8-1|A0A3Q1LNI4_BOVIN Computationally mapped isoform of ITPR interacting domain containing 2 OS=Bos taurus OX=9913 GN=ITPRID2 PE=4 SV=2 CANONICAL=A0A3Q1LNI4-1" }, "locus": { "chromosome": "2", "start_pos": 14690957, "end_pos": 14655980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086714.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086714.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064868.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064868.2" } ] } }, { "isoform_ac": "E1BET5-1", "url": "https://www.uniprot.org/uniprotkb/E1BET5/entry", "sequence": { "sequence": "MDRPLVASAEAEEELEWQVASRRRKAWAKCRGSWQASETEDLSTEATTQDEDEDEDEDDLSGTKLPAAAGRGNVPNEKIAIWLKDCRTPLGASLDEQSGSTLKGVLVRNGGSFEDDLSLGAEANHLHEIDAQIDNCSNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSDKETDSPPPLTRSNTANRLMKTLSKLNLCIEKTEKGEGSTPSLAVDKGKIVNISVMEESGNKNDQKSQKVVKKKESSSVLATVKEEVSGSSAALVENSDIDGLSDEANSNFNREAESGQSQETQSHENKLDEESGFLETDLGGDFNMSSHSELENSGELKNVPLCTPEKEPCAPLMIPSIRNIMAQQKDSFEMEEVQSTEGEAPHVPTTYQLGLNKSKRDQLLRTASQHSDSSGFAEDSTDCLSLNHLQVHESLQAMGSSADSCDSETTVTSFGEDLVTPTVQDQRYFNESEEESLTCPQIEREKAATVAEKRSDGQDSLLCQTVENIGHQQSTWSAGDHATEITERKEDVSPAQPVELLREASAESDVDKSSECEFVQYTTHHILKSLASIEAKCGEKGAENTTGSPSSVDRVNTALQRAQMKVCSLSNQRVGRSLIKSKDLLKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYKYTQEEEQRLEKEVTEHDGQSSVKSTIFISPTSGKKEADAPSEVTRLEECHQRRTPACSLPAPAPVSQSTCSLHSLHSEWQERHLCEHMRTLSTHSVPSVAGAACSAFPCPLGCPYSHRHAASPYRACSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDLAAAPYSTQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERYEVDQLQSLRNSVRMELQDLELQLEERLLGLEEQLRPVHLPSAFRPSALMGMCGSRSADNLSCPSPLNVMEPVTELMREQSYLKSELGLGHGEMGFEIPPGESSESVFSQATSESSSVCSGPSHASRRTGVPPIDSVGKPKTHLVPSKKLFRASVALTPTAPSRTGSVQTPPDVESSEEAGATEETSEAVGPKSEVEEEQGKVSLLPAAEEVHKNVEQDELQQVIREVCVGPVSCVILELSRIYTGGGVICASEDTCC", "length": 1256, "header": "tr|E1BET5-1|A0A3Q1LNI4_BOVIN Computationally mapped isoform of ITPR interacting domain containing 2 OS=Bos taurus OX=9913 GN=ITPRID2 PE=4 SV=2 CANONICAL=A0A3Q1LNI4-1" }, "locus": { "chromosome": "2", "start_pos": 14690957, "end_pos": 14655304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001241.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001241.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001241.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001241.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 316, "start_aa": "Thr", "end_pos": 316, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr316", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 804, "start_aa": "Thr", "end_pos": 804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr804", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:538826", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538826", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNI4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1057, "end_pos": 1059, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 925, "end_pos": 927, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LNI4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1258, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LNI4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNI4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LNI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNI4" }, { "id": "SM01257", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01257" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ITPR-interacting", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 303, "start_aa": "Gln", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 316, 804 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1057, "end_pos": 1059 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 925, "end_pos": 927 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", 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"https://www.uniprot.org/uniprotkb/A0A3Q1LNL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGAKNRRNRNRKNENKKKAKTEKRAVVEAEGKREATDTVRSAEGKREATGAAKTQAKAISKAGPRADAVAVVKPASKNKIVTEMKEHLPDVRPKAEDEANRAARFCSAAQATAESRFTCKDKTRTDTCFGAGEEANVGSWFWNGEEIGKHFSAKDEGKADTGPPSCAEKLEPVAGTSCKARPGAEEEEEENVIGSWFWDGDETSFDPNPRPVSRIIKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGFRSQVTCEKKPPSYVVLASAEENTRSSPVATAAARPSRSTPSSSQPVSEFPFGSDPCIQTIEEIRRQIRIREVNGIKPFSCPCKMECYMDSEEFERLITLLKSTTDPLIHKIAQIAMGIINVHPFAQEFINEVGVVTLIESLLSFPSSEMRKKAVITLNPPSGDERQRKVELHVKHMCKETISFPLNSPGQQSGLKILGQLTTDSNHHHIVANYFSELFHLLSLGNRKTRNLVLKVLLNMSENPTAARDMTNTESLAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHSSYTTLMAIFREVKVIIETM", "length": 568, "header": "tr|A0A3Q1LNL2-1|A0A3Q1LNL2_BOVIN Isoform 1 of G protein-coupled receptor associated sorting protein 3 OS=Bos taurus OX=9913 GN=GPRASP3 PE=3 SV=1 CANONICAL=A0A3Q1LNL2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNL2/entry", "sequence": { "sequence": "MPGAKNRRNRNRKNENKKKAKTEKRAVVEAEGKREATDTVRSAEGKREATGAAKTQAKAISKAGPRADAVAVVKPASKNKIVTEMKEHLPDVRPKAEDEANRAARFCSAAQATAESRFTCKDKTRTDTCFGAGEEANVGSWFWNGEEIGKHFSAKDEGKADTGPPSCAEKLEPVAGTSCKARPGAEEEEEENVIGSWFWDGDETSFDPNPRPVSRIIKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGFRSQVTCEKKPPSYVVLASAEENTRSSPVATAAARPSRSTPSSSQPVSEFPFGSDPCIQTIEEIRRQIRIREVNGIKPFSCPCKMECYMDSEEFERLITLLKSTTDPLIHKIAQIAMGIINVHPFAQEFINEVGVVTLIESLLSFPSSEMRKKAVITLNPPSGDERQRKVELHVKHMCKETISFPLNSPGQQSGLKILGQLTTDSNHHHIVANYFSELFHLLSLGNRKTRNLVLKVLLNMSENPTAARDMTNTESLAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHSSYTTLMAIFREVKVIIETM", "length": 568, "header": "tr|A0A3Q1LNL2-1|A0A3Q1LNL2_BOVIN Isoform 1 of G protein-coupled receptor associated sorting protein 3 OS=Bos taurus OX=9913 GN=GPRASP3 PE=3 SV=1 CANONICAL=A0A3Q1LNL2-1" }, "locus": { "chromosome": "X", "start_pos": 49888671, "end_pos": 49886968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065828.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065828.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061599.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061599.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 247, "start_aa": "Thr", "end_pos": 247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:107131311", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131311", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RYE8-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "GPRASP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGVKNASKKNRSRKNENKKKAKTEKRAGVEAEAKKEATGVVRSVPKTQAKAVAKAGSQEDAVAEMKAASKNKVVSEMKEGVLADISPKAEDEATRSSCSVVKASAESRSTRKDKTGIDTQPRAGEEASVGSSSQNGGEASNGFSAKDEGKADTGPLSCAEKLEPVAGATCKAKPGAEEEEEENVIGNWFWDGDETSFDPNPRPVSRIIKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGFRSQAQSEAKPPSYIVLASAEENTHSLPAATAGPSRSTASCSQSVPEYPFGSDPCIQTIEEIRRQIRIREVNGIKPFACPCKMECYMDSEEFEKLVTLLKSTTDPLIHKIAQIAMGIINVHPFAQEFINEVGVVTLVESLLSFPSSEMRKKAVITLNTPSGDERQRKVELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDSNHHHIVANYFSELFNLLSLGNRKTRNLVLKVLLNMSENPTAARDMINTKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKVIIETM", "length": 558 }, "evidence": [ { "id": "A0A3Q1LNL2", "url": "https://omabrowser.org/oma/group/A0A3Q1LNL2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HXC7-1", "protein_name": "Protein BHLHb9", "gene_name": "LOC100767015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTGSKNKARAQAKLDKRASGQAKALAEREAANAGRAGGKNRDKGKPKWGNKADAASETRGGSKGRAAAEMKEGGRSEHKALGKDFNHKYEYKGARSSRKEKASSDTWFWTGEESGLNSWFWKGEEVSYDTVPQCENKSNTGTQGRTEESEPTPKASHKSRAEEEEEENVIGNWFWEGDDTSYDPNPKPVFRIVKPQPVDEINEKNRPKDWSEVTIWPKAPAVTPAVLGYTSQDSSESRPSSFIVLASNEEKASKTACTKNTRSGLQPIPEYPFGSDPCIQTLDEIRQQIKIREMNGIKPFACPCKVECYLDSPEFEKLVNILKSTTDPLIHKIAQIAMGLHKVHPFAREFINEVGVVTLIESLLSFSSPETRKKTVITLNSSGDDRQHKVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVASYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYSTLTAIFREVKGIIERM", "length": 536 }, "evidence": [ { "id": "A0A3Q1LNL2", "url": "https://omabrowser.org/oma/group/A0A3Q1LNL2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6PB60-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "Gprasp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGSKNKARAQAKLEKRASAQARAVAEREAANANRGAGKSRDKGKGKAGSKSDAVAEVKAGSKGKVVAETKEGARPESKALVKGTSDFNHRTENKFARSTRKDKPSSDNWFWAGEDSGINSWFWKGEELSNNSVAKCENKPSTSIQARAEEPAPRTSHKSRSGAEEEEEENVIGNWFWEGDDTGFDTDPKPVFKIVKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGYRSQDSSEARSSSYIVLASNEEETSTACTKNTRSSLQSIPEYPFGSDPCIQTLDEIRQQIKIREENGIKPFACPCKLECYLDSPEFEKLVNILKSTTDPLIHKIAQIAMGIHKVHPFAQEFINEVGVVTLIESLLSFSSPEVSIKKAVITLNSSGDDRYNKVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVVSYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLTAIFREVKGIIERM", "length": 539 }, "evidence": [ { "id": "A0A3Q1LNL2", "url": "https://omabrowser.org/oma/group/A0A3Q1LNL2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PI77-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "GPRASP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWFWNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFWEGDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSEASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPIPECRFDSDPCIQTIDEIRRQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPFAQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPSGDERQRKIELHVKHMCKETMSFPLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENPTAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHIRKGSIVVVDHLSYNTLMAIFREVKEIIETM", "length": 547 }, "evidence": [ { "id": "A0A3Q1LNL2", "url": "https://omabrowser.org/oma/group/A0A3Q1LNL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71HP2-1", "protein_name": "G protein-coupled receptor associated sorting protein 3", "gene_name": "Gprasp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGSKNKARAQAKLEKRASAQAKAAAEREAANAGRGAGKNRDKGKGKAGSKTDAVAEAKAGSKSKVVAETKEGARPESKAVAKGTSDFNHKAENKYARSARKDKPSSDSWFWAGEDSGINSWFWKGEEVSNNSVAKCENKPSTSIQARVEEHTPRTSHKSRSGAEEEEEENVIGNWFWEGDDTGFDSDPKPVFKIVKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGYRSQDSSEGRPSSYIVLASNEEETSTTCTKNTRSSLQPIPEYPFGSDPCIQTLDEIRQQIKIREENGIKPFACPCKMECYLDSPEFEKLVNILKSTTDPLIHKIAQIAMGIHKVHPFAQEFINEVGVVTLIESLLSFSSPEVSIKKAVITLNSSGDDRQQMVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVVSYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLTAIFREVKGIIERM", "length": 539 }, "evidence": [ { "id": "A0A3Q1LNL2", "url": "https://omabrowser.org/oma/group/A0A3Q1LNL2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNL2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNL2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNL2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LNL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNL2" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 559, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 247, 292 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 491, "end_pos": 493 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LNQ4-1", "uniprot_ac": "A0A3Q1LNQ4", "uniprot_id": "A0A3Q1LNQ4_BOVIN", "mass": { "chemical_mass": 35021.0, "monoisotopic_mass": 35021.0 }, "refseq": {}, "gene_names": [ { "name": "OR1L8E", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4" } ] }, { "name": "OR1L18", "type": "synonym", "evidence": [ { "id": "A0A3Q1LNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1L8E", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4", "locus": { "chromosome": "11", "start_pos": 93368888, "end_pos": 93367941, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000062570", "url": "https://www.ensembl.org/id/ENSBTAG00000062570" } ] } } ], "crossref": [ { "id": "A0A3Q1LNQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000051762", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051762", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNQ4", "url": "https://www.orthodb.org/?gene=A0A3Q1LNQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERLNQTSGVSEFILLGLSSRPEDQKPLFILFLIMYLVTITGNVLIILAISSDPQLHTPMYVFLSVLSFTDIWYTTTIVPRMLVDFLSEKTISYAGCLTQMYFIYALGNTDNCLLAAMAYDRYVAICDPFHYVTIMSHCRCVLLVAFSCSLPHLHSLLHILLLNQLTFCDSNVVHHFLCDINPLLKLSCSSIFVNDLTIKTEGLVFWVTPFLCIVFSYVRILMAVLRIPSAAGKRKAFSTCGSHFTVVILFYGSIFYVYLQPLSSYTVQDRVAALVYTVLTSMLNPFIYSLRNKDMKRGLGKLLGRRKS", "length": 309, "header": "tr|A0A3Q1LNQ4-1|A0A3Q1LNQ4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR1L8E PE=3 SV=2 CANONICAL=A0A3Q1LNQ4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNQ4-1", 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1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LNQ4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LNQ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNQ4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LNQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNQ4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 289, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LNS1-1", "uniprot_ac": "A0A3Q1LNS1", "uniprot_id": "A0A3Q1LNS1_BOVIN", "mass": { "chemical_mass": 46643.0, "monoisotopic_mass": 46643.0 }, "refseq": { "ac": "XP_002693941", "name": "immunoglobulin mu Fc receptor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693941" }, "gene_names": [ { "name": "FCMR", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1" } ] }, { "name": "FCMR", "type": "synonym", "evidence": [ { "id": "XP_002693941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693941" } ] } ], "protein_names": [ { "name": "Fc mu receptor", "type": "synonym", "evidence": [ { "id": "A0A3Q1LNS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1/entry#names_and_taxonomy" } ] }, { "name": "immunoglobulin mu Fc receptor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_002693941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693941" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNS1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FCMR", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1", "locus": { "chromosome": "16", "start_pos": 4683832, "end_pos": 4707282, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019796", "url": "https://www.ensembl.org/id/ENSBTAG00000019796" } ] } } ], "crossref": [ { "id": "A0A3Q1LNS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LNS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019796", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019796", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511564", "url": "https://www.ncbi.nlm.nih.gov/gene/511564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511564", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511564", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LNS1", "url": "https://www.orthodb.org/?gene=A0A3Q1LNS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1B8P1", "url": "https://www.orthodb.org/?gene=E1B8P1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11860:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11860:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002693941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNS1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RU00", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RU00-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8P1", "url": "https://www.uniprot.org/uniprotkb/E1B8P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8P1-1", "url": "https://www.uniprot.org/uniprotkb/E1B8P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLWLWALYFLPVVGAPKVLPEVKMEGMLGGSITIECPLPETHVRIYLCRTIDESGRCTTVVSSNKYVREEFKHRVTLEQCPDRNLFLVVMTELTKNDSGIYACGVGGNTDRGKTQQITLTVHSVYEPSWEEEPMPEPPAWFNRFLQMHLPPWFQMPAHASSLTFMSKVTTPAQRIKSPRAHQASPNPSVTHRPRVFRASSVATAEPTIFLPAITTSKTSDQKGLLRLQTASYNHQTRLHRQRASNQGPGAASGMEDQGVFVLIPTILGLILLALLGLLAKRIIQRRKALSRRVRRLAVRMRTLDASQRALSRRPRVSRRPRTPSNIYSACPRRPRGVDAAGGRAASPPVPGAPAASAQPQVPEIPWLHVPSLKIDCEYVSFCHQPAAKVEDTDSDDYVNVACLTHLSSCAPEPRPWCQ", "length": 419, "header": "tr|A0A3Q1LNS1-1|A0A3Q1LNS1_BOVIN Isoform 1 of Fc mu receptor OS=Bos taurus OX=9913 GN=FCMR PE=4 SV=2 CANONICAL=A0A3Q1LNS1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1/entry", "sequence": { "sequence": "MDLWLWALYFLPVVGAPKVLPEVKMEGMLGGSITIECPLPETHVRIYLCRTIDESGRCTTVVSSNKYVREEFKHRVTLEQCPDRNLFLVVMTELTKNDSGIYACGVGGNTDRGKTQQITLTVHSVYEPSWEEEPMPEPPAWFNRFLQMHLPPWFQMPAHASSLTFMSKVTTPAQRIKSPRAHQASPNPSVTHRPRVFRASSVATAEPTIFLPAITTSKTSDQKGLLRLQTASYNHQTRLHRQRASNQGPGAASGMEDQGVFVLIPTILGLILLALLGLLAKRIIQRRKALSRRVRRLAVRMRTLDASQRALSRRPRVSRRPRTPSNIYSACPRRPRGVDAAGGRAASPPVPGAPAASAQPQVPEIPWLHVPSLKIDCEYVSFCHQPAAKVEDTDSDDYVNVACLTHLSSCAPEPRPWCQ", "length": 419, "header": "tr|A0A3Q1LNS1-1|A0A3Q1LNS1_BOVIN Isoform 1 of Fc mu receptor OS=Bos taurus OX=9913 GN=FCMR PE=4 SV=2 CANONICAL=A0A3Q1LNS1-1" }, "locus": { "chromosome": "16", "start_pos": 4707023, "end_pos": 4689499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071054.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071054.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061684.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061684.2" } ] } }, { "isoform_ac": "A0AAA9RU00-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU00/entry", "sequence": { "sequence": "MKLDAWMIVGAPKVLPEVKMEGMLGGSITIECPLPETHVRIYLCRTIDESGRCTTVVSSNKYVREEFKHRVTLEQCPDRNLFLVVMTELTKNDSGIYACGVGGNTDRGKTQQITLTVHSVYEPSWEEEPMPEPPAWFNRFLQMHLPPWFQMPAHASSLTFMSKVTTPAQRIKSPRAHQASPNPSVTHRPRVFRASSVATAEPTIFLPAITTSKTSDQKGLLRLQTASYNHQTRLHRQRASNQGPGAASGMEDQGVFVLIPTILGLILLALLGLLAKRIIQRRKALSRRVRRLAVRMRTLDASQRALSRRPRVSRRPRTPSNIYSACPRRPRGVDAAGGRAASPPVPGAPAASAQPQVPEIPWLHVPSLKIDCEYVSFCHQPAAKVEDTDSDDYVNVACLTHLSSCAPEPRPWCQ", "length": 414, "header": "tr|A0AAA9RU00-1|A0A3Q1LNS1_BOVIN Computationally mapped isoform of Fc mu receptor OS=Bos taurus OX=9913 GN=FCMR PE=4 SV=1 CANONICAL=A0A3Q1LNS1-1" }, "locus": { "chromosome": "16", "start_pos": 4699470, "end_pos": 4689499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128609.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128609.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076584.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076584.1" } ] } }, { "isoform_ac": "E1B8P1-1", "url": "https://www.uniprot.org/uniprotkb/E1B8P1/entry", "sequence": { "sequence": "MDLWLWALYFLPVVGAPKVLPEVKMEGMLGGSITIECPLPETHVRIYLCRTIDESGRCTTVVSSNKYVREEFKHRVTLEQCPDRNLFLVVMTELTKNDSGIYACGVGGNTDRGKTQQITLTVHSVYEPSWEEEPMPEPPAWFNRFLQMHLPPWFQMPAHASSLTFMSKVTTPAQRIKSPRAHQASPNPSVTHRPRVFRASSVATAEPTIFLPAITTSKTSDQKGLLRLQTASYNHQTRLHRQRASNQGPGAASGMEDQGVFVLIPTILGLILLALLGLLAKRIIQRRKALSRRVRRLAVRMRTLDASQRALSRRPRVSRRPRTPSNIYSACPRRPRGVDAAGGRAASPPVPGAPAASAQPQNHLPPWLGPEQHF", "length": 374, "header": "tr|E1B8P1-1|A0A3Q1LNS1_BOVIN Computationally mapped isoform of Fc mu receptor OS=Bos taurus OX=9913 GN=FCMR PE=4 SV=4 CANONICAL=A0A3Q1LNS1-1" }, "locus": { "chromosome": "16", "start_pos": 4707023, "end_pos": 4683834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026376.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026376.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026376.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026376.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511564", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511564", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNS1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1" } ], "pmid": "" }, { "name": "high-affinity IgM receptor activity", "id": "GO:0002172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002172", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNS1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNS1" } ], "pmid": "" }, { "name": "polymeric immunoglobulin 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"https://www.ensembl.org/id/ENSBTAP00000096225.1" } ] } }, { "isoform_ac": "A0AAA9TTU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTU2/entry", "sequence": { "sequence": "MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDMDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSPSMTMSV", "length": 368, "header": "tr|A0AAA9TTU2-1|A0A3Q1LNU3_BOVIN Computationally mapped isoform of Single stranded DNA binding protein 3 OS=Bos taurus OX=9913 GN=SSBP3 PE=4 SV=1 CANONICAL=A0A3Q1LNU3-1" }, "locus": { "chromosome": "3", "start_pos": 92006180, "end_pos": 91841707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117574.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117574.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100504.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100504.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "head morphogenesis", "id": "GO:0060323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060323", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNU3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU3" } ], "pmid": "" }, { "name": "prechordal plate formation", "id": "GO:0021501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021501", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNU3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU3" } ], "pmid": "" }, { "name": "midbrain-hindbrain boundary initiation", "id": "GO:0021547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021547", "evidence": [ { "database": "UniProtKB", "id": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377238" }, "gene_names": [ { "name": "OR8B1AU", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU4" } ] }, { "name": "OR8B1AU", "type": "synonym", "evidence": [ { "id": "NP_001377238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377238" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LNU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 8 subfamily B member 1AU", "type": "synonym", "evidence": [ { "id": "NP_001377238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377238" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377238", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377238" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNU4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU4#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LNU4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8B1AU", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU4", "locus": { "chromosome": "29", "start_pos": 26894206, "end_pos": 26895138, 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LSQ0-1", "uniprot_ac": "A0A3Q1LSQ0", "uniprot_id": "A0A3Q1LSQ0_BOVIN", "mass": { "chemical_mass": 80171.0, "monoisotopic_mass": 80171.0 }, "refseq": { "ac": "XP_005226200", "name": "transforming acidic coiled-coil-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226200" }, "gene_names": [ { "name": 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"id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TACC1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0", "locus": { "chromosome": "27", "start_pos": 34007044, "end_pos": 33910544, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004238", "url": "https://www.ensembl.org/id/ENSBTAG00000004238" } ] } } ], "crossref": [ { "id": "A0A3Q1LSQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LSQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004238", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507012", "url": "https://www.ncbi.nlm.nih.gov/gene/507012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507012", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAANHVN", "url": "https://omabrowser.org/oma/group/PAANHVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LP00", "url": "https://www.orthodb.org/?gene=A0A3Q1LP00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSQ0", "url": "https://www.orthodb.org/?gene=A0A3Q1LSQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MSQ8", "url": "https://www.orthodb.org/?gene=F1MSQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13924", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13924", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13924:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13924:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005226200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226200", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP00", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP00-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MSQ8", "url": "https://www.uniprot.org/uniprotkb/F1MSQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MSQ8-1", "url": "https://www.uniprot.org/uniprotkb/F1MSQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFSPWQILSPVQWARWTWSAVRGGGAGEDEAGGPEGDPEDEDSQAETKSLSFSSDSEGNFETPETETPIRSPLKESCESHLGLAGSGAKTQDSQEEEEELVAEVVGSCSSAAASRPSGQEAAPPAGGSRPVKDFREEPEHDASKISVVRPFSIESRNCGDVPVAPGTAALLGPAVGVQDNEAMTAGAALEADPGAGSPRPEPGAGRSRLRKPRPVPLRKKALGSELSEATPALEDMRPVGEDGKAGSQKCAPEMMETPGGDAHDSGAEQPEDARSPPLQCEFDFAEDTETVESRRALPRKPGRKPGSRVMPQVHGAKAPPEPGPGASPTLRPRGGPLARQHSPPLSAQGSYRFDPDLFDESSDPFKPSMTFASGDFDSPAGNQVNEILESPKKAKSRLITSGCKVKKYEAQSLALDGCSQDEGAVISQISDISNRDGHATDEEKLASTSSVQKPTGAEGKGEPEDDLEYFECSNVPVSAINHAFSSSEAGSEKDPCQKMEKDGSTVPALLESPVEKTPVSVACGVESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD", "length": 742, "header": "tr|A0A3Q1LSQ0-1|A0A3Q1LSQ0_BOVIN Isoform 1 of Transforming acidic coiled-coil containing protein 1 OS=Bos taurus OX=9913 GN=TACC1 PE=3 SV=1 CANONICAL=A0A3Q1LSQ0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP00-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP00/entry", "sequence": { "sequence": "MAFSPWQILSPVQWARWTWSAVRGGGAGEDEAGGPEGDPEDEDSQAETKSLSFRSGCKVKKYEAQSLALDGCSQDEGAVISQISDISNRDGHATDEEKLASTSSVQKPTGAEGKGEPEDDLEYFECSNVPVSAINHAFSSSEAGSEKDPCQKMEKDGSTVPALLESPVEKTPVSVACGVESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD", "length": 395, "header": "tr|A0A3Q1LP00-1|A0A3Q1LSQ0_BOVIN Computationally mapped isoform of Transforming acidic coiled-coil containing protein 1 OS=Bos taurus OX=9913 GN=TACC1 PE=3 SV=2 CANONICAL=A0A3Q1LSQ0-1" }, "locus": { "chromosome": "27", "start_pos": 34006040, "end_pos": 33944426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068339.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068339.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061776.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061776.2" } ] } }, { "isoform_ac": "A0A3Q1LSQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0/entry", "sequence": { "sequence": "MAFSPWQILSPVQWARWTWSAVRGGGAGEDEAGGPEGDPEDEDSQAETKSLSFSSDSEGNFETPETETPIRSPLKESCESHLGLAGSGAKTQDSQEEEEELVAEVVGSCSSAAASRPSGQEAAPPAGGSRPVKDFREEPEHDASKISVVRPFSIESRNCGDVPVAPGTAALLGPAVGVQDNEAMTAGAALEADPGAGSPRPEPGAGRSRLRKPRPVPLRKKALGSELSEATPALEDMRPVGEDGKAGSQKCAPEMMETPGGDAHDSGAEQPEDARSPPLQCEFDFAEDTETVESRRALPRKPGRKPGSRVMPQVHGAKAPPEPGPGASPTLRPRGGPLARQHSPPLSAQGSYRFDPDLFDESSDPFKPSMTFASGDFDSPAGNQVNEILESPKKAKSRLITSGCKVKKYEAQSLALDGCSQDEGAVISQISDISNRDGHATDEEKLASTSSVQKPTGAEGKGEPEDDLEYFECSNVPVSAINHAFSSSEAGSEKDPCQKMEKDGSTVPALLESPVEKTPVSVACGVESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD", "length": 742, "header": "tr|A0A3Q1LSQ0-1|A0A3Q1LSQ0_BOVIN Isoform 1 of Transforming acidic coiled-coil containing protein 1 OS=Bos taurus OX=9913 GN=TACC1 PE=3 SV=1 CANONICAL=A0A3Q1LSQ0-1" }, "locus": { "chromosome": "27", "start_pos": 34006040, "end_pos": 33944426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070399.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070399.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060049.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060049.1" } ] } }, { "isoform_ac": "F1MSQ8-1", "url": "https://www.uniprot.org/uniprotkb/F1MSQ8/entry", "sequence": { "sequence": "MAFSPWQILSPVQWARWTWSAVRGGGAGEDEAGGPEGDPEDEDSQAETKSLSFSSDSEGNFETPETETPIRSPLKESCESHLGLAGSGAKTQDSQEEEEELVAEVVGSCSSAAASRPSGQEAAPPAGGSRPVKDFREEPEHDASKISVVRPFSIESRNCGDVPVAPGTAALLGPAVGVQDNEAMTAGAALEADPGAGSPRPEPGAGRSRLRKPRPVPLRKKALGSELSEATPALEDMRPVGEDGKAGSQKCAPEMMETPGGDAHDSGAEQPEDARSPPLQCEFDFAEDTETVESRRALPRKPGRKPGSRVMPQVHGAKAPPEPGPGASPTLRPRGGPLARQHSPPLSAQGSYRFDPDLFDESSDPFKPSMTFASGDFDSPAGNQVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKYEAQSLALDGCSQDEGAVISQISDISNRDGHATDEEKLASTSSVQKPTGAEGKGSEKDPCQKMEKDGSTVPALLESPVEKTPVSVACGVESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD", "length": 724, "header": "tr|F1MSQ8-1|F1MSQ8_BOVIN Computationally mapped isoform of Transforming acidic coiled-coil containing protein 1 OS=Bos taurus OX=9913 GN=TACC1 PE=3 SV=5 CANONICAL=A0A3Q1LSQ0-1" }, "locus": { "chromosome": "27", "start_pos": 34006040, "end_pos": 33944426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005554.8", "url": "https://www.ensembl.org/id/ENSBTAT00000005554.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005554.8", "url": "https://www.ensembl.org/id/ENSBTAP00000005554.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507012", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AHG9-1", "protein_name": "Transforming, acidic coiled-coil containing protein 1", "gene_name": "Tacc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSVTEVAFAKLRLVTARASGRAGGREAAAPPCLWPFLPAASCEVTRGLAVMGGSHSQGRGPGLAWETPPTAVDAASDSEGNFETPEAETPIRSSLKESCDSSLGLSEPEAKPQESREADEQPVAELIEKCSPDACSRSSGNEAPQATIDSYSVKDVRGKAEHDVSKISVVRPFSIETRDCTDDPAAHGCVPVLPGKALPSTTPEATQDQPMMDRGMGVTLEAFTEVNLKTGGPCPEPVPSRSRLRKPKPVSLRKKTAGDNTFEPEMLMEGSLLPKASSPWIPEESDKNSNPSLLRGLRAHKSPLNLKEAASIHCNSAGDSGVDLQEGSRASPLKLDDFTEDGRSVETRSALPKQPGRKPSHKLAPNIRKDGSSKPVGVEQLTDPTIEDASLAQTSPKLDPSKWGRPNFNSFGSCPILQSSPPVSSKGSYHLDPDNVNADESGDPCKPATALTGSGFCSATGNHVNEILDSPKKAQSRLITSGCKVKKYETQSLDLDACSQDEGAVISQIADIPNRDGHATDEEKLASTSCSQKSAGAEVKGVEKEAYQKMEEEELTVHGLLETSSEKAPVSVACGGESPLDGICLSEADKTAVLTLIREEIITKEIEANEWKKKYEETREEVLEMRKIVAEYEKTIAQMIEDEQRTNMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKVHAEEKLDRANEEIAQVRSKAKAESAALHAGLRREQMKVESLERALQQKNQEIEELTKICDELIAKLGKAD", "length": 793 }, "evidence": [ { "id": "A0A3Q1LSQ0", "url": "https://omabrowser.org/oma/group/A0A3Q1LSQ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cerebral cortex development", "id": "GO:0021987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021987", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "astral microtubule organization", "id": "GO:0030953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030953", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "nuclear glucocorticoid receptor binding", "id": "GO:0035259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035259", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "peroxisome proliferator activated receptor binding", "id": "GO:0042975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042975", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" }, { "name": "nuclear retinoid X receptor binding", "id": "GO:0046965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046965", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LSQ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 742, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LSQ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LSQ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LSQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSQ0" }, { "id": "PF05010", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transforming acidic coiled-coil-containing protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 536, "end_pos": 735, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LP31-1", "uniprot_ac": "A0A3Q1LP31", "uniprot_id": "A0A3Q1LP31_BOVIN", "mass": { "chemical_mass": 66347.0, "monoisotopic_mass": 66347.0 }, "refseq": { "ac": "NP_001229240", "name": "atlastin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229240" }, "gene_names": [ { "name": "ATL2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LP31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ] }, { "name": "ARL6IP2", "type": "synonym", "evidence": [ { "id": "NP_001229240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229240" } ] }, { "name": "ATL2", "type": "synonym", "evidence": [ { "id": "NP_001229240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229240" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like 6 interacting protein 2", "type": "synonym", "evidence": [ { "id": "NP_001229240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229240" } ] }, { "name": "Atlastin GTPase 2", "type": "synonym", "evidence": [ { "id": "A0A3Q1LP31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31/entry#names_and_taxonomy" } ] }, { "name": "atlastin-2", "type": "synonym", "evidence": [ { "id": "NP_001229240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229240" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATL2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31", "locus": { "chromosome": "11", "start_pos": 20672449, "end_pos": 20740102, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016167", "url": "https://www.ensembl.org/id/ENSBTAG00000016167" } ] } } ], "crossref": [ { "id": "A0A3Q1LP31", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LP31", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016167", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100140212", "url": "https://www.ncbi.nlm.nih.gov/gene/100140212", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100140212", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140212", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GQVMFKR", "url": "https://omabrowser.org/oma/group/GQVMFKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LP31", "url": "https://www.orthodb.org/?gene=A0A3Q1LP31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001229240", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001229240", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RX89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RX89-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIW6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TC66", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TC66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF90", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF90-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE28", "url": "https://www.uniprot.org/uniprotkb/E1BE28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE28-1", "url": "https://www.uniprot.org/uniprotkb/E1BE28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGDEVTRSQEPHQGLRRRRRTSDSNTGVNHVSSTTLLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIERPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEEFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 583, "header": "tr|A0A3Q1LP31-1|A0A3Q1LP31_BOVIN Isoform 1 of Atlastin GTPase 2 OS=Bos taurus OX=9913 GN=ATL2 PE=3 SV=1 CANONICAL=A0A3Q1LP31-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31/entry", "sequence": { "sequence": "MAEGDEVTRSQEPHQGLRRRRRTSDSNTGVNHVSSTTLLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIERPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEEFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 583, "header": "tr|A0A3Q1LP31-1|A0A3Q1LP31_BOVIN Isoform 1 of Atlastin GTPase 2 OS=Bos taurus OX=9913 GN=ATL2 PE=3 SV=1 CANONICAL=A0A3Q1LP31-1" }, "locus": { "chromosome": "11", "start_pos": 20740072, "end_pos": 20673898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074416.1", "url": "https://www.ensembl.org/id/ENSBTAT00000074416.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058768.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058768.1" } ] } }, { "isoform_ac": "A0AAA9RX89-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX89/entry", "sequence": { "sequence": "MAEGDEVTRSQEPHQGLRRRRRTSDSNTGVNHVSSTTLLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIERPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEEFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQSLLKISHLQYSADSRILEVPLSQNKSVEESKACTSIFSTVEVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 624, "header": "tr|A0AAA9RX89-1|A0A3Q1LP31_BOVIN Computationally mapped isoform of Atlastin GTPase 2 OS=Bos taurus OX=9913 GN=ATL2 PE=3 SV=1 CANONICAL=A0A3Q1LP31-1" }, "locus": { "chromosome": "11", "start_pos": 20740072, "end_pos": 20673898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134702.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134702.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078115.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078115.1" } ] } }, { "isoform_ac": "A0AAA9SIW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW6/entry", "sequence": { "sequence": "MGPAVEEDAQRAGGADTSLPGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIERPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEEFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 564, "header": "tr|A0AAA9SIW6-1|A0A3Q1LP31_BOVIN Computationally mapped isoform of Atlastin GTPase 2 OS=Bos taurus OX=9913 GN=ATL2 PE=3 SV=1 CANONICAL=A0A3Q1LP31-1" }, "locus": { "chromosome": "11", "start_pos": 20739471, "end_pos": 20673898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130367.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130367.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082488.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082488.1" } ] } }, { "isoform_ac": "A0AAA9TC66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC66/entry", "sequence": { "sequence": "MAEGDEVTRSQEPHQGLRRRRRTSDSNTGVNHVSSTTLLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIERPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEEFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQNSKLGLTSIY", "length": 554, "header": "tr|A0AAA9TC66-1|A0A3Q1LP31_BOVIN Computationally mapped isoform of Atlastin GTPase 2 OS=Bos taurus OX=9913 GN=ATL2 PE=3 SV=1 CANONICAL=A0A3Q1LP31-1" }, "locus": { "chromosome": "11", "start_pos": 20740072, "end_pos": 20675421, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101036.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101036.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093688.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093688.1" } ] } }, { "isoform_ac": "A0AAA9TF90-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF90/entry", "sequence": { "sequence": "MAEGDEVTRSQEPHQGLRRRRRTSDSNTGVNHVSSTTLLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIERPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEEFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 564, "header": "tr|A0AAA9TF90-1|A0A3Q1LP31_BOVIN Computationally mapped isoform of Atlastin GTPase 2 OS=Bos taurus OX=9913 GN=ATL2 PE=3 SV=1 CANONICAL=A0A3Q1LP31-1" }, "locus": { "chromosome": "11", "start_pos": 20740072, "end_pos": 20673898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110462.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110462.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095527.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095527.1" } ] } }, { "isoform_ac": "E1BE28-1", "url": "https://www.uniprot.org/uniprotkb/E1BE28/entry", "sequence": { "sequence": "MAEGDEVTRSQEPHQGLRRRRRTSDSNTGVNHVSSTTLLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIERPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEEFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQRSPRKVFSKLFEVTRRRMVHRVLSSAQRQRLSSNNNKKKN", "length": 584, "header": "tr|E1BE28-1|A0A3Q1LP31_BOVIN Computationally mapped isoform of Atlastin GTPase 2 OS=Bos taurus OX=9913 GN=ATL2 PE=3 SV=4 CANONICAL=A0A3Q1LP31-1" }, "locus": { "chromosome": "11", "start_pos": 20740072, "end_pos": 20674401, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061283.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061283.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053652.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053652.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100140212", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140212", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AWD2-1", "protein_name": "Atlastin GTPase 2", "gene_name": "ATL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEGDEAARRQQPHLGLRRRRRTSDPNTAVNHVSSTTLLGESYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGAREIYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFVGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQRSPRKVFSKLFEVTRRRMVHRALSSAQRQRLSSNNNKKKN", "length": 584 }, "evidence": [ { "id": "A0A3Q1LP31", "url": "https://omabrowser.org/oma/group/A0A3Q1LP31/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0L7Q4-1", "protein_name": "Atlastin GTPase 2", "gene_name": "Atl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEGDEAARRQQPQQGLRRRRQTSDSSVGVNHVSSTTSLGEDYEDADLVNSDEVMRKPCPVQIVLAHEDDHNFELDEEALERILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGSNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDAYCRSMEQVCGGDKPYIAPSDLERKHLDLKEVALKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQVAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 583 }, "evidence": [ { "id": "A0A3Q1LP31", "url": "https://omabrowser.org/oma/group/A0A3Q1LP31/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PA06-1", "protein_name": "Atlastin-2", "gene_name": "Atl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEGDEAARRQQPQQGLRRRRQTSDSSVGVNHVSSTTSLGEDYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDVYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVALKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALTSLCTWAYVKYSGEFREIGTMIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 583 }, "evidence": [ { "id": "A0A3Q1LP31", "url": "https://omabrowser.org/oma/group/A0A3Q1LP31/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NHH9-1", "protein_name": "Atlastin-2", "gene_name": "ATL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAETLWEQVLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLKTD", "length": 583 }, "evidence": [ { "id": "A0A3Q1LP31", "url": "https://omabrowser.org/oma/group/A0A3Q1LP31/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" }, { "name": "GTPase-dependent fusogenic activity", "id": "GO:0140523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140523", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network membrane organization", "id": "GO:1990809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990809", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane fusion", "id": "GO:0016320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016320", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum tubular network membrane", "id": "GO:0098826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098826", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", "E1BJA0-1", "A0A3Q1N147-1", "A0AAF6YME1-1", "F1MX39-1", "Q1RMJ6-1", "Q2HJ68-1", "Q2HJG3-1", "Q17QI8-1", "Q3SZA1-1", "A0ABI0NZ89-1", "A0ABI0P4Y3-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T898", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B9", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDX0", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1N147", "gene_name": "RAB1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] } ] }, { "uniprot_ac": "A0A3Q1NCE9", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] } ] }, { "uniprot_ac": "A0A3Q1NEF8", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] } ] }, { "uniprot_ac": "A0A3S5ZPA2", "gene_name": "RAB40B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPA2", 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LP41-1", "uniprot_ac": "A0A3Q1LP41", "uniprot_id": "A0A3Q1LP41_BOVIN", "mass": { "chemical_mass": 59265.0, "monoisotopic_mass": 59265.0 }, "refseq": { "ac": "XP_005218444", "name": "vacuolar fusion protein MON1 homolog B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218444" }, "gene_names": [ { "name": "MON1B", "type": "recommended", "evidence": [ { "id": "A0A3Q1LP41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" } ] }, { "name": "MON1B", "type": "synonym", "evidence": [ { "id": "XP_005218444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218444" } ] } ], "protein_names": [ { "name": "Vacuolar fusion protein MON1 homolog", "type": "recommended", "evidence": [ { "id": "A0A3Q1LP41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41/entry#names_and_taxonomy" } ] }, { "name": "vacuolar fusion protein MON1 homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005218444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218444" } ] } ], "function": [ { "annotation": "Plays an important role in membrane trafficking through the secretory apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S3Z7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3Z7#function" }, { "database": "UniProtKB", "id": "RU367048", "url": "https://www.uniprot.org/uniprotkb/RU367048#function" }, { "database": "UniProtKB", "id": "A0AAA9TY55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY55#function" }, { "database": "UniProtKB", "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MON1B", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41", "locus": { "chromosome": "18", "start_pos": 4421584, "end_pos": 4411395, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000052957", "url": "https://www.ensembl.org/id/ENSBTAG00000052957" } ] } } ], "crossref": [ { "id": "A0A3Q1LP41", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LP41", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000052957", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000052957", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510379", "url": "https://www.ncbi.nlm.nih.gov/gene/510379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TKTCAIT", "url": "https://omabrowser.org/oma/group/TKTCAIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LP41", "url": "https://www.orthodb.org/?gene=A0A3Q1LP41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13027:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13027:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005218444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218444", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP41-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3Z7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAGGDTAAPVPGDAEDLEEMRFPSEEAEDGGGVHKDLPDPGDAGLEKAGSKTKDQSPSLLLQSEAPSCTYGLWSPSASEGSPLGGPEIGSGGPGGDPSDEDWRSKRKHVFVLSEAGKPIYSRYGSVEALSTTMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFARKQNYDLRRLLAGSERTLDRLLDSVERDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLVTAAQERTVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTDPEAFHDMATCRRLVEEGMHSLRAMRALREAASFSNAASASASAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSPSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILAVTKLLRWVKKEEDRLFIRYPPKYSTPPAAPAASTDQASHNGLFTGP", "length": 548, "header": "tr|A0A3Q1LP41-1|A0A3Q1LP41_BOVIN Isoform 1 of Vacuolar fusion protein MON1 homolog OS=Bos taurus OX=9913 GN=MON1B PE=3 SV=1 CANONICAL=A0A3Q1LP41-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP41-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41/entry", "sequence": { "sequence": "MEAGGDTAAPVPGDAEDLEEMRFPSEEAEDGGGVHKDLPDPGDAGLEKAGSKTKDQSPSLLLQSEAPSCTYGLWSPSASEGSPLGGPEIGSGGPGGDPSDEDWRSKRKHVFVLSEAGKPIYSRYGSVEALSTTMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFARKQNYDLRRLLAGSERTLDRLLDSVERDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLVTAAQERTVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTDPEAFHDMATCRRLVEEGMHSLRAMRALREAASFSNAASASASAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSPSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILAVTKLLRWVKKEEDRLFIRYPPKYSTPPAAPAASTDQASHNGLFTGP", "length": 548, "header": "tr|A0A3Q1LP41-1|A0A3Q1LP41_BOVIN Isoform 1 of Vacuolar fusion protein MON1 homolog OS=Bos taurus OX=9913 GN=MON1B PE=3 SV=1 CANONICAL=A0A3Q1LP41-1" }, "locus": { "chromosome": "18", "start_pos": 4419322, "end_pos": 4412094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076386.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076386.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058655.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058655.1" } ] } }, { "isoform_ac": "A0AAA9S3Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3Z7/entry", "sequence": { "sequence": "MEAGGDTAAPVPGDAEDLEEMRFPSEEAEDGGGVHKDLPDPGDAGLEKAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFARKQNYDLRRLLAGSERTLDRLLDSVERDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLVTAAQERTVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTDPEAFHDMATCRRLVEEGMHSLRAMRALREAASFSNAASASASAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSPSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILAVTKLLRWVKKEEDRLFIRYPPKYSTPPAAPAASTDQASHNGLFTGP", "length": 441, "header": "tr|A0AAA9S3Z7-1|A0A3Q1LP41_BOVIN Computationally mapped isoform of Vacuolar fusion protein MON1 homolog OS=Bos taurus OX=9913 GN=MON1B PE=3 SV=1 CANONICAL=A0A3Q1LP41-1" }, "locus": { "chromosome": "18", "start_pos": 4419322, "end_pos": 4412094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120513.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120513.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076842.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076842.1" } ] } }, { "isoform_ac": "A0AAA9TY55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY55/entry", "sequence": { "sequence": "MVPSQLRCRVKTEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFARKQNYDLRRLLAGSERTLDRLLDSVERDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLVTAAQERTVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTDPEAFHDMATCRRLVEEGMHSLRAMRALREAASFSNAASASASAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSPSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILAVTKLLRWVKKEEDRLFIRYPPKYSTPPAAPAASTDQASHNGLFTGP", "length": 404, "header": "tr|A0AAA9TY55-1|A0A3Q1LP41_BOVIN Computationally mapped isoform of Vacuolar fusion protein MON1 homolog OS=Bos taurus OX=9913 GN=MON1B PE=3 SV=1 CANONICAL=A0A3Q1LP41-1" }, "locus": { "chromosome": "18", "start_pos": 4419322, "end_pos": 4411831, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097144.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097144.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101591.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101591.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480JRT2-1", "protein_name": "Vacuolar fusion protein MON1 homolog", "gene_name": "MON1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAGGDIAAPAPGDAEDLEDTRFPSEEARDGGGVQEDPPDPGDGSVEETGSETKDQPPSLPLPSEAPSCPYGFWGPAASESCPMGGPESGSGAQGGDPSDEDWRSKRKHVFVLSEAGKPIYSRYGSVEALSTTMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFARKQNYDLRRLLAGSERTLDRLLDSVERDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLVTAAQERTVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTDPEAFHDMATCRRLVEDGMHSLGAMRALREAASFSDAPSANASAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHNTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPAAPAASTDQASHNGLFTGP", "length": 548 }, "evidence": [ { "id": "A0A3Q1LP41", "url": "https://omabrowser.org/oma/group/A0A3Q1LP41/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6G3S1-1", "protein_name": "Vacuolar fusion protein MON1 homolog", "gene_name": "Mon1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METGGDNAVPAPGGVEDLVDTQFPREEAGDSEEVHSSTLDPGDGEPEDTGSKTKDQPSSLLSPLPQAEAPSSTCEHWKTAASDSSPTGEPQRSSEGQGEDPSDGDPNDGDPSDGDPNDGDPNDGDPSDGDPNDGDPSDEDWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSVEQDPGALLLGAVRCVPLARPLRDALGTLLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDSMPVCLLLLGTNREAFHAMAACRRLVEDGMHNLGALRTLGEAASFSNGPAANAPAYSVQAVGAPGLRHFLYKPLDIPEQHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAAAILVVTKLLRWVRKEEDRLFIRYPPKYSTPPSTSSDQAPNNGLFTGL", "length": 583 }, "evidence": [ { "id": "A0A3Q1LP41", "url": "https://omabrowser.org/oma/group/A0A3Q1LP41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7EY38-1", "protein_name": "Vacuolar fusion protein MON1 homolog", "gene_name": "mon1bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHNGQESGNMEEVKICDPSILPQCPDHTDTDVPSENHCVNEDHRTPSDPEGLLESADHSSEQDVLPQEPSTEMQKLHVEDDRSLCPGGSETDSGKASQDSALVDNSNDDSGEFVVTVLARGKMEEQGMGMKGASSPLSETGTPLGPPSHRNEDVTADSWRQHRKHVFVLSEAGKPIYSRYGSEEALSSTMGVMMALVSFVQSGDNIIRSVYSDEHTVVFMQRGPLVLVSVSCSRQSEQQLRNELVYVYNQIVSMLTQASITRIFEHKKNYDLRRLLAGSEKILDGLLNLVDSDPSFLLCAVHCLPLASSLRDSLSQILQKAITPNLVFSILIAKNQLLTIVQEKMVIDDARLEPADLHLLLNLIGASSAFQAGEIWTPICLPSFNPDCYFYAYISYLDPPECTVCLVLLSTDKEAFYSVAECKRKIEEAMQTQNALKSIAKAQSYSVSQVGVSDLRHFMYKPFDVPDNHRQLTQFTSPEMEAPYSSEEERMRLLDLYRDLHGRIHSASRPLKLIYHVAERETLLAWVTSKFELYTCFSPLVTKTCAINAITKLLRWIKKEEERLFIRYPPKYSTTPNPSRSSKTDAH", "length": 588 }, "evidence": [ { "id": "A0A3Q1LP41", "url": "https://omabrowser.org/oma/group/A0A3Q1LP41/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3H957-1", "protein_name": "Vacuolar fusion protein MON1 homolog", "gene_name": "Mon1b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAGGDSAVPAPGGVEDLVDTQLPIEEAGDSEGVHSSTPDPGDGDPEDTGSMAKDQPPRLLSPGPQAEAPSSTCEHWKTAASDENPSGEPEGSSEDQREDPSDGDPNDGDPNDEDWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSVEQDPGALLLGAVRCVPLARPLRDALGTLLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDSMPVCLLLLGTNREAFHAMAACRRLVEDGMHNLGALRTLGEAASFSNGPAANAPAYSVHAVGAPGLRHFLYKPLDIPDQHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVRKEEDRLFIRYPPKYSTPPSTSVDQAPNNGLFTGL", "length": 558 }, "evidence": [ { "id": "A0A3Q1LP41", "url": "https://omabrowser.org/oma/group/A0A3Q1LP41/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7L1V2-1", "protein_name": "Vacuolar fusion protein MON1 homolog B", "gene_name": "MON1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSPSPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAFHAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFTGL", "length": 547 }, "evidence": [ { "id": "A0A3Q1LP41", "url": "https://omabrowser.org/oma/group/A0A3Q1LP41/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMQ8-1", "protein_name": "Vacuolar fusion protein MON1 homolog B", "gene_name": "Mon1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAGGDNAVPAPGGVEDLVDTQFPREEAGDSERVHASTLDPGDGDPEDTGSKDQPSSLLSPLPQTEAASSTCEHWETAAASDSSPPGEPESNSEGQGEDPDDGGDPSDEDWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAVSRTPQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSVEQDPGALLLGAVRCVPLARPLRDALGTLLRRCTAPGLALSVLAVGGRLITVAQERNVLAECRLDPADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDSMPVCLLLLGTNREAFHAMAACRRLVEDGMHNLGALRTLGEAANFSNGPAASAPAYSVQAVGAPGLRHFLYKPLDIPEQHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVRKEEDRLFIRYPPKYSTPPSTSADQAPNNGLFTGL", "length": 553 }, "evidence": [ { "id": "A0A3Q1LP41", "url": "https://omabrowser.org/oma/group/A0A3Q1LP41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SKN1-1", "protein_name": "Vacuolar fusion protein MON1 homolog", "gene_name": "MON1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATSDSRSSPSSSDTEFADPNPSSDPETNSERVQSQLESMNLSQPSEVSDGSHTEFSGGGDDNDDEVASANGNEGGVSNGGLLREGVAGTSGGEVLLRAENPVEMEAGEEPPSPTSSGYDGERGSSGGATSTYKADDGSEDEIREANVDGDTASQHEAAWLPGKRHVDEDDASTSWRKRKKHFFILSNSGKPIYSRYGDEHKLAGFSATLQAIISFVENGGDRVNLVKAGNHQVVFLVKGPIYLVCISCTDETYEYLRGQLDLLYGQMILILTKSIDRCFEKNAKFDMTPLLGGTDAVFSSLVHSFSWNPATFLHAYTCLPLPYALRQATGTILQEVCASGVLFSLLMCRHKVVSLAGAQKASLHPDDLLLLSNFVMSSESFRTSESFSPICLPRYNAQAFLHAYVHFFDDDTYVILLTTRSDAFHHLKDCRVRLEAVLLKSNILSVVQRSIAEGGMRVEDVPIDRRRRSSTTNQEQDSPGPDISVGTGGPFGLWHFMYRSIYLDQYISSEFSPPVTSHRQQKSLYRAYQKLYASMHVKGLGPHKTQYRRDENYTLLCWVTPDFELYAAFDPLADKAMAIKICNQVCQRVKDVENEVFLQGASPFSW", "length": 607 }, "evidence": [ { "id": "A0A3Q1LP41", "url": "https://omabrowser.org/oma/group/A0A3Q1LP41/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "early viral transcription", "id": "GO:0019085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019085", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" } ], "pmid": "" }, { "name": "late viral transcription", "id": "GO:0019086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019086", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Mon1-Ccz1 complex", "id": "GO:0035658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035658", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP41", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LP41-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 548, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LP41-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LP41" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LP41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" }, { "id": "PF19036", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 first Longin", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 230, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LP41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" }, { "id": "PF19037", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 second Longin", "eco_id": "ECO_0000259", "start_pos": 274, "end_pos": 366, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LP41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP41" }, { "id": "PF19038", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FUZ/MON1/HPS1 third Longin", "eco_id": "ECO_0000259", "start_pos": 407, "end_pos": 514, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LP42-1", "uniprot_ac": "A0A3Q1LP42", "uniprot_id": "A0A3Q1LP42_BOVIN", "mass": { "chemical_mass": 18420.0, "monoisotopic_mass": 18420.0 }, "refseq": { "ac": "XP_003585853", "name": "heat shock protein beta-7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585853" }, "gene_names": [ { "name": "HSPB7", "type": "recommended", "evidence": [ { "id": "A0A3Q1LP42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ] }, { "name": "HSPB7", "type": "synonym", "evidence": [ { "id": "XP_003585853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585853" } ] } ], "protein_names": [ { "name": "Heat shock protein beta-7", "type": "recommended", "evidence": [ { "id": "A0A3Q1LP42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42/entry#names_and_taxonomy" } ] }, { "name": "Cardiovascular heat shock protein", "type": "synonym", "evidence": [ { "id": "A0A3Q1LP42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42/entry#names_and_taxonomy" } ] }, { "name": "heat shock protein beta-7", "type": "synonym", "evidence": [ { "id": "XP_003585853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585853" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HSPB7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42", "locus": { "chromosome": "2", "start_pos": 136057316, "end_pos": 136053981, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000055045", "url": "https://www.ensembl.org/id/ENSBTAG00000055045" } ] } } ], "crossref": [ { "id": "A0A3Q1LP42", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LP42", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000055045", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000055045", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06479", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06479", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512251", "url": "https://www.ncbi.nlm.nih.gov/gene/512251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512251", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNPYMEK", "url": "https://omabrowser.org/oma/group/CNPYMEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LP42", "url": "https://www.orthodb.org/?gene=A0A3Q1LP42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46907", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46907", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46907:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46907:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003585853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585853", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP42-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SD26", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SD26-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHRTSSTFRAERSFHSSSSSSSSASHSLPAQDPPMEKALSMFSEDFGGFMRPHSEPLAFPALPTARAAGPGNIKTLGDAYEFAVDVSDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRQPPTEHVQQTFRTEIKI", "length": 169, "header": "tr|A0A3Q1LP42-1|A0A3Q1LP42_BOVIN Isoform 1 of Heat shock protein beta-7 OS=Bos taurus OX=9913 GN=HSPB7 PE=3 SV=1 CANONICAL=A0A3Q1LP42-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP42-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42/entry", "sequence": { "sequence": "MSHRTSSTFRAERSFHSSSSSSSSASHSLPAQDPPMEKALSMFSEDFGGFMRPHSEPLAFPALPTARAAGPGNIKTLGDAYEFAVDVSDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRQPPTEHVQQTFRTEIKI", "length": 169, "header": "tr|A0A3Q1LP42-1|A0A3Q1LP42_BOVIN Isoform 1 of Heat shock protein beta-7 OS=Bos taurus OX=9913 GN=HSPB7 PE=3 SV=1 CANONICAL=A0A3Q1LP42-1" }, "locus": { "chromosome": "2", "start_pos": 136056312, "end_pos": 136054180, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079646.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079646.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061829.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061829.1" } ] } }, { "isoform_ac": "A0AAA9SD26-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD26/entry", "sequence": { "sequence": "MWLDRQMWPGRAGLQETVLAWGQLWCQGPRGLGPGPLWSSESCGALGRHADPLRAWALPTARAAGPGNIKTLGDAYEFAVDVSDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRQPPTEHVQQTFRTEIKI", "length": 164, "header": "tr|A0AAA9SD26-1|A0A3Q1LP42_BOVIN Computationally mapped isoform of Heat shock protein beta-7 OS=Bos taurus OX=9913 GN=HSPB7 PE=3 SV=2 CANONICAL=A0A3Q1LP42-1" }, "locus": { "chromosome": "2", "start_pos": 136056312, "end_pos": 136054478, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133115.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133115.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081427.2", "url": "https://www.ensembl.org/id/ENSBTAP00000081427.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512251", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M9W1-1", "protein_name": "Heat shock protein beta-7", "gene_name": "Hspb7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSHRTSSAFRAERSFHSSSSSSSSSSSSASRALPAQDPPMEKALSMFSEDFGSFMRPHSEPLAFPARPGGQGSVKTLGDAYEFTVDMRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPDDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI", "length": 169 }, "evidence": [ { "id": "A0A3Q1LP42", "url": "https://omabrowser.org/oma/group/A0A3Q1LP42/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BV54-1", "protein_name": "Heat shock protein family B (small) member 7", "gene_name": "HSPB7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNLKSSSAFRSEHSFHQHSRSSSPACPMELFGSFARPHEQMGFPARPGTSGNVKTLGNTYQFTVDVSDFAPEDIIVTTSNNQIEVHAEKLAGDGTVMNTFTHKCQLPEDVDPTSVSSSLGDNGTLTIRAIRQPAKHSEHVQQTFRTEIKI", "length": 150 }, "evidence": [ { "id": "A0A3Q1LP42", "url": "https://omabrowser.org/oma/group/A0A3Q1LP42/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P35385-1", "protein_name": "Heat shock protein beta-7", "gene_name": "Hspb7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHRTSSAFRAERSFRSSSSSSSSSSSSASRALPAQDPPMEKALSMFSDDFGSFMLPHSEPLAFPARPGGQGNIKTLGDAYEFTVDMRDFSPEDIIVTTFNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI", "length": 169 }, "evidence": [ { "id": "A0A3Q1LP42", "url": "https://omabrowser.org/oma/group/A0A3Q1LP42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QUK5-1", "protein_name": "Heat shock protein beta-7", "gene_name": "Hspb7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SSSSSSASRALPAQDPPMEKALSMFSEDFGSFMLPHSEPLTFPARPGGQGNIKTLGDAYEFTVDMRDFSPEDIIVTTSNNHIEVRAEKKP", "length": 90 }, "evidence": [ { "id": "A0A3Q1LP42", "url": "https://omabrowser.org/oma/group/A0A3Q1LP42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UBY9-1", "protein_name": "Heat shock protein beta-7", "gene_name": "HSPB7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKALSMFSDDFGSFMRPHSEPLAFPARPGGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHVQQTFRTEIKI", "length": 170 }, "evidence": [ { "id": "A0A3Q1LP42", "url": "https://omabrowser.org/oma/group/A0A3Q1LP42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "filamin binding", "id": "GO:0031005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031005", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP42", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LP42-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 169, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LP42-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LP42" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LP42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP42" }, { "id": "PS01031", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SHSP", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 169, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LP69-1", "uniprot_ac": "A0A3Q1LP69", "uniprot_id": "A0A3Q1LP69_BOVIN", "mass": { "chemical_mass": 29212.0, "monoisotopic_mass": 29212.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Large ribosomal subunit protein uL30", "type": "recommended", "evidence": [ { "id": "A0A3Q1LP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L7", "type": "synonym", "evidence": [ { "id": "A0A3Q1LP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69#function" }, { "database": "UniProtKB", "id": "ARBA00045415", "url": "https://www.uniprot.org/uniprotkb/ARBA00045415#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69", "locus": {} } ], "crossref": [ { "id": "A0A3Q1LP69", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LP69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019994", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019994", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01657", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01657", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SYYVDAQ", "url": "https://omabrowser.org/oma/group/SYYVDAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11524", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11524", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11524:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11524:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LP69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VIEFMQIKRKVIFSLGAEEKKKKVPAVPETLKKKRKNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMAKMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRISVNELIYKRGYGKINKKRIALTDNTLIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN", "length": 248, "header": "tr|A0A3Q1LP69-1|A0A3Q1LP69_BOVIN Isoform 1 of Large ribosomal subunit protein uL30 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0A3Q1LP69-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69/entry", "sequence": { "sequence": "VIEFMQIKRKVIFSLGAEEKKKKVPAVPETLKKKRKNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMAKMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRISVNELIYKRGYGKINKKRIALTDNTLIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN", "length": 248, "header": "tr|A0A3Q1LP69-1|A0A3Q1LP69_BOVIN Isoform 1 of Large ribosomal subunit protein uL30 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0A3Q1LP69-1" }, "locus": { "chromosome": "2", "start_pos": 91271766, "end_pos": 91270024, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026631.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026631.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061861.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061861.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P05737-1", "protein_name": "Large ribosomal subunit protein uL30A", "gene_name": "RPL7A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSMN", "length": 244 }, "evidence": [ { "id": "A0A3Q1LP69", "url": "https://omabrowser.org/oma/group/A0A3Q1LP69/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P32100-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "RpL7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPAPVVKKPAAKKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRKKENLVRAEKYQNEYIKAEQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASNFLWPFKLNTPTGGWRKKANHYVNGGDFGNREDQINRLLRKMV", "length": 252 }, "evidence": [ { "id": "A0A3Q1LP69", "url": "https://omabrowser.org/oma/group/A0A3Q1LP69/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P60039-1", "protein_name": "Large ribosomal subunit protein uL30x", "gene_name": "RPL7C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAESKVVVPESVLKKIKRQEEWALAKKDEAVAAKKKSVEARKLIFKRAEQYAKEYAEKDNELIRLKREAKLKGGFYVDPEAKLLFIIRIRGINAIDPKTKKILQLLRLRQIFNGVFLKVNKATVNMLRRVEPYVTYGYPNLKSVKELIYKRGYGKLNHQRIALTDNSIVDQALGKHGIICVEDLIHEIMTVGPHFKEANNFLWPFQLKAPLGGLKKKRNHYVEGGDAGNRENFINELVRRMN", "length": 242 }, "evidence": [ { "id": "A0A3Q1LP69", "url": "https://omabrowser.org/oma/group/A0A3Q1LP69/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP69", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP69", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377346", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377346" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP70", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP70#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP70", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP70" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4F71", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP70", "locus": { "chromosome": "10", "start_pos": 28052323, "end_pos": 28051394, 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"MKEPRIFPRERPTPWTRAPLPPRGRLDGSLGPQGGPVLNTGHPLGMNSDPFLMASSSLGGNLAPFPRNPSPFPTSSGSLASNPAPFPAGARDPGLASFPRGMNPTSTGAVSFPRPGGLLGPSPGSTLNPRAGALPGPGPLSNPRLGSLPGPGPVSNPRPSGLLGTGPDPRSGGPMGPGSGPSLRAGVLLTPGNGPPNPRPVGLGPGPSPNLRSGFVGTNPAPRSSMFPGPGLGPNPRSSGLGPGLGPNPRAGGLGPGPNLDARAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGANSASFSQASGNMGTSPSSMARLPGPIGPNSGPGSRGIGLPGPNPSPLSRAPGPVGPNSAHFARPAGPMGVNANPFPRGTGSGGLNPAAFSQSSNTLASNPINFQRSAGLQGSSPAVFPRASGPLGPNPANFPRATGLQGPSPATFPRSIGPLGPGQVTFPRPAPGPLGSSPAGPVGINPAPFARPTGTLGVNPASFPRMNGPVSKTLVPFPRVGSLPGTNPAAFPRPGGPMAAMYPNGMLPP", "length": 540, "header": "tr|A0A3Q1LP80-1|A0A3Q1LP80_BOVIN Isoform 1 of DERPC proline and glycine rich nuclear protein OS=Bos taurus OX=9913 GN=DERPC PE=4 SV=2 CANONICAL=A0A3Q1LP80-1" }, "locus": { "chromosome": "18", "start_pos": 36334893, "end_pos": 36333274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107257.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107257.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089532.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089532.1" } ] } }, { "isoform_ac": "A0A3Q1LQZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQZ8/entry", "sequence": { "sequence": "MKEPRIFPRERPTPWTRAPLPPRGRLDGSLGPQGGPVLNTGHPLGMNSDPFLMASSSLGGNLAPFPRNPSPFPTSSGSLASNPAPFPAGARDPGLASFPRGMNPTSTGAVSFPRPGGLLGPSPGSTLNPRAGALPGPGPLSNPRLGSLPGPGPVSNPRPSGLLGTGPDPRSGGPMGPGSGPSLRAGVLLTPGNGPPNPRPVGLGPGPSPNLRSGFVGTNPAPRSSMFPGPGLGPNPRSSGLGPGPNLDARAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGANSASFSQASGNMGTSPSSMARLPGPIGPNSGPGSRGIGLPGPNPSPLSRAPGPVGPNSAHFARPAGPMGVNANPFPRGTGSGGLNPAAFSQSSNTLASNPINFQRSAGLQGSSPAVFPRASGPLGPNPANFPRATGLQGPSPATFPRSIGPLGPGQVTFPRPAPGPLGSSPAGPVGINPAPFARPTGTLGVNPASFPRMNGPVSKTLVPFPRVGSLPGTNPAAFPRPGGPMAAMYPNGMLPP", "length": 527, "header": "tr|A0A3Q1LQZ8-1|A0A3Q1LP80_BOVIN Computationally mapped isoform of DERPC proline and glycine rich nuclear protein OS=Bos taurus OX=9913 GN=DERPC PE=4 SV=2 CANONICAL=A0A3Q1LP80-1" }, "locus": { "chromosome": "18", "start_pos": 36334893, "end_pos": 36333274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066522.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066522.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057448.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057448.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:116621585", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:116621585", "resource": "KEGG Pathway" }, { "id": "R-BTA-2142845", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2142845", "resource": "Reactome", "description": "Hyaluronan metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "polysaccharide biosynthetic process", "id": "GO:0000271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000271", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP80", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP80" } ], "pmid": "" }, { "name": "extracellular matrix assembly", "id": "GO:0085029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0085029", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP80", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP80" } ], "pmid": "" }, { "name": "hyaluronan biosynthetic process", "id": "GO:0030213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030213", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP80", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP80", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP80" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP80", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP80" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LP80", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP80" } ], "pmid": "" } ] }, { "name": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377677" }, "gene_names": [ { "name": "OR52S20", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5" } ] }, { "name": "OR52S20", "type": "synonym", "evidence": [ { "id": "NP_001377677", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377677" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 52 subfamily S member 20", "type": "synonym", "evidence": [ { "id": "NP_001377677", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377677" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377677", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377677" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR52S20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5", "locus": { "chromosome": "15", "start_pos": 49637698, "end_pos": 49636754, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000063020", "url": "https://www.ensembl.org/id/ENSBTAG00000063020" } ] } } ], "crossref": [ { "id": "A0A3Q1LPF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000053514", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053514", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15951", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15951", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107131374", "url": "https://www.ncbi.nlm.nih.gov/gene/107131374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:107131374", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131374", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAETRIF", "url": "https://omabrowser.org/oma/group/CAETRIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPF5", "url": "https://www.orthodb.org/?gene=A0A3Q1LPF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377677", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377677", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPNNISFHPSTFLLIGIPGMEAIHTWISMPFCLIYLTALLGNFSILFIIRTDSNLHEPMYFFLCMLSVADLILSTTAMPKILSIFWFHDREIYFEACLVQVFLIHSLCSMASGFILAMAFDRYVAICNPLRHSIILTHRVIQNLGLAIVFRGVVLFCPQPFMLRWLPYCRTNVIPHTYCEFMALIKLACAETRICRTYSLTAAFLTGGLDFLLILCSYVVILYTVFHLPSKAARLKTLGTCGSHVCVILVAYTPAFFSFLTHRFGHNVAPHIHIFVANIYILVPPMVNPMIYGIRTKRIREQFLQVLTSHKF", "length": 314, "header": "tr|A0A3Q1LPF5-1|A0A3Q1LPF5_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR52S20 PE=3 SV=1 CANONICAL=A0A3Q1LPF5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5/entry", "sequence": { "sequence": "MSLPNNISFHPSTFLLIGIPGMEAIHTWISMPFCLIYLTALLGNFSILFIIRTDSNLHEPMYFFLCMLSVADLILSTTAMPKILSIFWFHDREIYFEACLVQVFLIHSLCSMASGFILAMAFDRYVAICNPLRHSIILTHRVIQNLGLAIVFRGVVLFCPQPFMLRWLPYCRTNVIPHTYCEFMALIKLACAETRICRTYSLTAAFLTGGLDFLLILCSYVVILYTVFHLPSKAARLKTLGTCGSHVCVILVAYTPAFFSFLTHRFGHNVAPHIHIFVANIYILVPPMVNPMIYGIRTKRIREQFLQVLTSHKF", "length": 314, "header": "tr|A0A3Q1LPF5-1|A0A3Q1LPF5_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR52S20 PE=3 SV=1 CANONICAL=A0A3Q1LPF5-1" }, "locus": { "chromosome": "15", "start_pos": 49637695, "end_pos": 49636754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067458.1", "url": "https://www.ensembl.org/id/ENSBTAT00000067458.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058807.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058807.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:107131374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131374", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACZ6-1", "protein_name": "Olfactory receptor", "gene_name": "Or52s20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQQMVSITPLSNITNLHPRIFLLLGIPGMEAIHTWLSVPFCLVYLGAHLGNFPLLFIVRIDSNPHEPMYFFLCMLSDTDLILSTTAMPKILSNFWFHNREIHFEACLVQVFLIRSLCSMASGFILAMALDRYVAICNALRHSAIPTHGVIRNLGIMSVVRGGLLFSPQPLMLRWLPYCRTNTIPHTYCEFMALIKLACAETRIFRLYSLTAAFLTGSLDFISIICSYIVILYTVFRLPSKAARLKTLGTCGSHVCVILVAYTPAFFSFLTHRCGHNVAPHIHIFVANIYLLVPPLANPMIYGIRTKTIRERFLQILTSKKIIK", "length": 323 }, "evidence": [ { "id": "A0A3Q1LPF5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LPF5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 314, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LPG3-1", "uniprot_ac": "A0A3Q1LPG3", "uniprot_id": "A0A3Q1LPG3_BOVIN", "mass": { "chemical_mass": 102561.0, "monoisotopic_mass": 102561.0 }, "refseq": {}, "gene_names": [ { "name": "RAB44", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3" } ] } ], "protein_names": [ { "name": "RAB44, member RAS onco family", "type": "synonym", "evidence": [ { "id": "A0A3Q1LPG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPG3", "url": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8873719", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8873719", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LPG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGLRVTRKGRKLGSSRRRQMREPADGQDVPVAPEPESWTSQSAEELQSFFQDCGAEERGFVTREDLAAAKFSFLSSEDELEMIFDWVDVERKGRLSLEEFSSGLKNIFGSSSSTHRLHRKRPLLSKRGSVATSFPVVEEANSEEKEAFFAFMEQLGASNSLPEQAEIWQLWRKLRQEEPQLAGNLEGFLAKMNSRLQEARADKEVLELTLRKRDTDHHREVRQLYEEMEQQIHREKQQLQAESDSRGLALSSQMQEVLEAKEREVQRLTEGQKELEAQLHRLSSTHQEASSENRQLREAERDLAGRLEEVRGQLQVTRGHLDAARGRVSWQMEEEPSVPRTGEEKAPDAQAASSEEAPLPGLFGDNDDWDQLLSGIASSGPPTPRVVRQISISEPHALLFAQEPSSDPGGSPRSSPGVPSGTEEEKGANPDGPDMSPPEQTGEPPSQEAKEESGLGPGVHFPWGLPGVSAGEPGSLVAAALKVLVPLEDGSPPQVTSSPPQASAGPSTQLQTSYPDDEGPGPGPVPPKPPRQREALHQDPHSAGSEPRLGSLGAGALLVGLDEPSQGLVPEGPAPMDGSEWGKWSPDAQEGRSGELQEAHGQVPGLSTLLPQSLEEESRAEERKAVDQGEWKFRSELTVEARGLKLEHSELPQLNPQPAPRPPDRAQAEVEAEAPAPRKPSEGFLPFLPMGAQPGDGAGPPEPTQTLPTRAELEAQPRPQPTTAHAEGEQAPSKSRKPRAENRPEDSRMDSGGPGLTPFPGDRTANEPLTDPDYAFHVIFLGDSNVGKTSFLYLLHQNNFATGLTATVGVDFRVKNLLVDNKRYALQLWDTAGQERYHSVTRQLLRKADGVVLMYDVTSQESFVHVRYWLDCLRDAESDDVVILLLGNKTDREEDRQVSTEAGQQLAQELGVSFGECSAALGHNILEPVVHLAR", "length": 936, "header": "tr|A0A3Q1LPG3-1|A0A3Q1LPG3_BOVIN Isoform 1 of RAB44, member RAS onco family OS=Bos taurus OX=9913 GN=RAB44 PE=4 SV=2 CANONICAL=A0A3Q1LPG3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3/entry", "sequence": { "sequence": 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Isoform 1 of RAB44, member RAS onco family OS=Bos taurus OX=9913 GN=RAB44 PE=4 SV=2 CANONICAL=A0A3Q1LPG3-1" }, "locus": { "chromosome": "23", "start_pos": 10641806, "end_pos": 10616635, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074232.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074232.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058817.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058817.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-8873719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8873719", "resource": "Reactome", "description": "RAB geranylgeranylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular 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{ "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3" } ], "pmid": "" }, { "name": "mast cell degranulation", "id": "GO:0043303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043303", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 890, "end_pos": 892, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LPG3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 936, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LPG3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPG3" } ], "lectin_list": [], "domain_list": [ { 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"length": 1728, "header": "tr|A0A3Q1LT16-1|A0A3Q1LT16_BOVIN Isoform 1 of Cortactin-binding protein 2 OS=Bos taurus OX=9913 GN=CTTNBP2 PE=4 SV=2 CANONICAL=A0A3Q1LT16-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI5/entry", "sequence": { "sequence": 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"length": 1642, "header": "tr|A0A3Q1LPI5-1|A0A3Q1LT16_BOVIN Computationally mapped isoform of Cortactin-binding protein 2 OS=Bos taurus OX=9913 GN=CTTNBP2 PE=4 SV=1 CANONICAL=A0A3Q1LT16-1" }, "locus": { "chromosome": "4", "start_pos": 50650775, "end_pos": 50482723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076107.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076107.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056840.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056840.1" } ] } }, { "isoform_ac": "A0A3Q1LT16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT16/entry", "sequence": { "sequence": "MSPDLALALQCQCCHHLVKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRLFRRQIELPYDPAIQLLGIHTEETRIERDTCTPMFIAALFIIARTWKQPRCPSADEWIRKLWYIYTMEYYSAIKKNTFESVLMRWMKLEPIIQSEARRKEVFIQERYGRFNLNDPFLALQRDYEAGASDKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKHVVLMLVKECKQLSGKVLEEAQKLEEVMAKLEEEKKKTSALEEELATEKRRSTEMEAQMEKQLSEFDTEREQLRAKLHREEAHTTDLKEEIDKMKKMIEQLKKGNDSKPSLSLPRKTKDRRLVSISVATEGPMTRSVACQTDLVVETAEPLKKLPLSVPVKPATGSPLVSAGAKGNACPSAASVRPGIERQVSHGDLIGSSLPTVPPPSANRIEENGPSTGSTPDLTSSPSPLPSAVSPASGHTPAPPPHSLHSPSASAPLHPGLNPRIQAARFRFQGSNANDPDQNGNTTQSPPSREVSPTSRDNLVAKQLARNTVTQALSRFTSPPAGAPPRPGASPTGDVGTYPPVGRTSLKTPGGARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIMDSSRASSTGIKADNKTVASPPSSLPQGNRVINEENLSKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAETPGLNQPACSESSLVIPTTTAFRSSINPVSASSRRAGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPIHAAVDTGNVDSLKLLMYHRAPAHGNKLQEEPGLAILDLDQEEEHHEGTSKPVVPADLINHADSEGWTAAHIAASKGFKNCLEVLCRHGGLEPERRDKCNRTAHDVATDDCKHLLENLNALKIPLRISVGETEPGNCGADDFECESTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDMTFSSTTDSSIGLSASSVRSITLGNVPWSAGQSFTQSPWDFMRTNKAEQVTVLLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIAHQLALCLKHRQMAAGFPCEIVRAEVDADFSKEQLVDLFISSACLIPVKQSPANKKIIVILENLEKSSLSELLGDFLGPLENHSTESPCTFQKGNGMSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFRGQVPSPCDPVCKTVDWALAVWRQLNSCLARLGTPEALLGPQHFLSCPVVPGHTQATVKWMSKLWNAVIAPRVQEAILSRASVKRQPGLGQTTKNPSQGQQAVVRAALSILLNKAVLHGCPLQRAELDQHTADFKGGSFPLSIVSSYSSCSKKKESGAWRKVSTSPRKKSGRFSSPTWNKPDLSEEGIKSNTILQLNCNRNASLSNQKSLENDLSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRRFDSSGNNPVFSATVNNPRMPVSQKEVSPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSKVTQCSQNTKRSSSSSNTRQIEINNNSRDLEPTQK", "length": 1728, "header": "tr|A0A3Q1LT16-1|A0A3Q1LT16_BOVIN Isoform 1 of Cortactin-binding protein 2 OS=Bos taurus OX=9913 GN=CTTNBP2 PE=4 SV=2 CANONICAL=A0A3Q1LT16-1" }, "locus": { "chromosome": "4", "start_pos": 50650775, "end_pos": 50454124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083298.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083298.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063576.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063576.2" } ] } }, { "isoform_ac": "A0AAA9S6E8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E8/entry", "sequence": { "sequence": "MSPDLALALQCQCCHHLVKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGASDKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKHVVLMLVKECKQLSGKVLEEAQKLEEVMAKLEEEKKKTSALEEELATEKRRSTEMEAQMEKQLSEFDTEREQLRAKLHREEAHTTDLKEEIDKMKKMIEQLKKGNDSKPSLSLPRKTKDRRLVSISVATEGPMTRSVACQTDLVVETAEPLKKLPLSVPVKPATGSPLVSAGAKGNACPSAASVRPGIERQVSHGDLIGSSLPTVPPPSANRIEENGPSTGSTPDLTSSPSPLPSAVSPASGHTPAPPPHSLHSPSASAPLHPGLNPRIQAARFRFQGSNANDPDQNGNTTQSPPSREVSPTSRDNLVAKQLARNTVTQALSRFTSPPAGAPPRPGASPTGDVGTYPPVGRTSLKTPGGARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIMDSSRASSTGIKADNKTVASPPSSLPQGNRVINEENLSKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAETPGLNQPACSESSLVIPTTTAFRSSINPVSASSRRAGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPIHAAVDTGNVDSLKLLMYHRAPAHGNKLQEEPGLAILDLDQEEEHHEGTSKPVVPADLINHADSEGWTAAHIAASKGFKNCLEVLCRHGGLEPERRDKCNRTAHDVATDDCKHLLENLNALKIPLRISVGETEPGNCGADDFECESTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDMTFSSTTDSSIGLSASSVRSITLGNVPWSAGQSFTQSPWDFMRTNKAEQVTVLLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIAHQLALCLKHRQMAAGFPCEIVRAEVDADFSKEQLVDLFISSACLIPVKQSPANKKIIVILENLEKSSLSELLGDFLGPLENHSTESPCTFQKGNGMSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFRGQVPSPCDPVCKTVDWALAVWRQLNSCLARLGTPEALLGPQHFLSCPVVPGHTQATVKWMSKLWNAVIAPRVQEAILSRASVKRQPGLGQTTKNPSQGQQAVVRAALSILLNKAVLHGCPLQRAELDQHTADFKGGSFPLSIVSSYSSCSKKKESGAWRKVSTSPRKKSGRFSSPTWNKPDLSEEGIKSNTILQLNCNRNASLSNQKRSVLSAAIKQPNAATVNQRLSWVFQELNLFFLFLEVKSPSVPRTPKEAAAAVIQGK", "length": 1540, "header": "tr|A0AAA9S6E8-1|A0A3Q1LT16_BOVIN Computationally mapped isoform of Cortactin-binding protein 2 OS=Bos taurus OX=9913 GN=CTTNBP2 PE=4 SV=1 CANONICAL=A0A3Q1LT16-1" }, "locus": { "chromosome": "4", "start_pos": 50650731, "end_pos": 50454124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115350.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115350.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079461.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079461.1" } ] } }, { "isoform_ac": "A0AAA9SCI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCI4/entry", "sequence": { "sequence": "MATDGASCEPDFSRAAEDAAGAPAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGASDKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKHVVLMLVKECKQLSGKVLEEAQKLEEVMAKLEEEKKKTSALEEELATEKRRSTEMEAQMEKQLSEFDTEREQLRAKLHREEAHTTDLKEEIDKMKKMIEQLKKGNDSKPSLSLPRKTKDRRLVSISVATEGPMTRSVACQTDLVVETAEPLKKLPLSVPVKPATGSPLVSAGAKGNACPSAASVRPGIERQVSHGDLIGSSLPTVPPPSANRIEENGPSTGSTPDLTSSPSPLPSAVSPASGHTPAPPPHSLHSPSASAPLHPGLNPRIQAARFRFQGSNANDPDQNGNTTQSPPSREVSPTSRDNLVAKQLARNTVTQALSRFTSPPAGAPPRPGASPTGDVGTYPPVGRTSLKTPGGARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIMDSSRASSTGIKADNKTVASPPSSLPQGNRVINEENLSKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAETPGLNQPACSESSLVIPTTTAFRSSINPVSASSRRAGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPIHAAVDTGNVDSLKLLMYHRAPAHGNKLQEEPGLAILDLDQEEEHHEGTSKPVVPADLINHADSEGWTAAHIAASKGFKNCLEVLCRHGGLEPERRDKCNRTAHDVATDDCKHLLENLNALKIPLRISVGETEPGNCGADDFECESTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDMTFSSTTDSSIGLSASSVRSITLGNVPWSAGQSFTQSPWDFMRTNKAEQVTVLLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIAHQLALCLKHRQMAAGFPCEIVRAEVDADFSKEQLVDLFISSACLIPVKQSPANKKIIVILENLEKSSLSELLGDFLGPLENHSTESPCTFQKGNGMSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFRGQVPSPCDPVCKTVDWALAVWRQLNSCLARLGTPEALLGPQHFLSCPVVPGHTQATVKWMSKLWNAVIAPRVQEAILSRASVKRQPGLGQTTKNPSQGQQAVVRAALSILLNKAVLHGCPLQRAELDQHTADFKGGSFPLSIVSSYSSCSKKKESGAWRKVSTSPRKKSGRFSSPTWNKPDLSEEGIKSNTILQLNCNRNASLSNQKLLIPGMI", "length": 1500, "header": "tr|A0AAA9SCI4-1|A0A3Q1LT16_BOVIN Computationally mapped isoform of Cortactin-binding protein 2 OS=Bos taurus OX=9913 GN=CTTNBP2 PE=4 SV=1 CANONICAL=A0A3Q1LT16-1" }, "locus": { "chromosome": "4", "start_pos": 50647795, "end_pos": 50482723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116979.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116979.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083097.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083097.1" } ] } }, { "isoform_ac": "F1MXS6-1", "url": "https://www.uniprot.org/uniprotkb/F1MXS6/entry", "sequence": { "sequence": "MSPDLALALQCQCCHHLVKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGASDKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKHVVLMLVKECKQLSGKVLEEAQKLEEVMAKLEEEKKKTSALEEELATEKRRSTEMEAQMEKQLSEFDTEREQLRAKLHREEAHTTDLKEEIDKMKKMIEQLKKGNDSKPSLSLPRKTKDRRLVSISVATEGPMTRSVACQTDLVVETAEPLKKLPLSVPVKPATGSPLVSAGAKGNACPSAASVRPGIERQVSHGDLIGSSLPTVPPPSANRIEENGPSTGSTPDLTSSPSPLPSAVSPASGHTPAPPPHSLHSPSASAPLHPGLNPRIQAARFRFQGSNANDPDQNGNTTQSPPSREVSPTSRDNLVAKQLARNTVTQALSRFTSPPAGAPPRPGASPTGDVGTYPPVGRTSLKTPGGARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIMDSSRASSTGIKADNKTVASPPSSLPQGNRVINEENLSKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAETPGLNQPACSESSLVIPTTTAFRSSINPVSASSRRAGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFKCVELLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPIHAAVDTGNVDSLKLLMYHRAPAHGNKLQEEPGLAILDLDQEEEHHEGTSKPVVPADLINHADSEGWTAAHIAASKGFKNCLEVLCRHGGLEPERRDKCNRTAHDVATDDCKHLLENLNALKIPLRISVGETEPGNCGADDFECESTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDMTFSSTTDSSIGLSASSVRSITLGNVPWSAGQSFTQSPWDFMRTNKAEQVTVLLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIAHQLALCLKHRQMAAGFPCEIVRAEVDADFSKEQLVDLFISSACLIPVKQSPANKKIIVILENLEKSSLSELLGDFLGPLENHSTESPCTFQKGNGMSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFRGQVPSPCDPVCKTVDWALAVWRQLNSCLARLGTPEALLGPQHFLSCPVVPGHTQATVKWMSKLWNAVIAPRVQEAILSRASVKRQPGLGQTTKNPSQGQQAVVRAALSILLNKAVLHGCPLQRAELDQHTADFKGGSFPLSIVSSYSSCSKKKESGAWRKVSTSPRKKSGRFSSPTWNKPDLSEEGIKSNTILQLNCNRNASLSNQKSLENDLSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRRFDSSGNNPVFSATVNNPRMPVSQKEVSPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSKVTQCSQNTKRSSSSSNTRQIEINNNSRDLEPTQK", "length": 1633, "header": "tr|F1MXS6-1|F1MXS6_BOVIN Computationally mapped isoform of Cortactin-binding protein 2 OS=Bos taurus OX=9913 GN=CTTNBP2 PE=4 SV=3 CANONICAL=A0A3Q1LT16-1" }, "locus": { "chromosome": "4", "start_pos": 50650775, "end_pos": 50454124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028619.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028619.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028619.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028619.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:530341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530341", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LT16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT16" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LT16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT16" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LT16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LT16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1296, "end_pos": 1298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1572, "end_pos": 1574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1718, "end_pos": 1720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 817, "end_pos": 819, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LT16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT16" }, { "id": "PF25408", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25408" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CortBP2/NAV1-like AAA+ ATPase lid", "eco_id": "ECO_0000259", "start_pos": 1384, "end_pos": 1453, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LT16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT16" }, { "id": "PF09727", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09727" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cortactin-binding protein-2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 57, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12106:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12106:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024841503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPL1-1", 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"length": 1168, "header": "tr|A0A3Q1LPL1-1|A0A3Q1LPL1_BOVIN Isoform 1 of VPS10 domain-containing receptor SorCS1 OS=Bos taurus OX=9913 GN=SORCS1 PE=3 SV=2 CANONICAL=A0A3Q1LPL1-1" }, "locus": { "chromosome": "26", "start_pos": 28129359, "end_pos": 27556455, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076748.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076748.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058939.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058939.2" } ] } }, { "isoform_ac": "A0A3Q1MSI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSI9/entry", "sequence": { "sequence": "MGKVGAGGVSPAGLSALLAGAGLLVLCAPGSCGGGSCCPPRHPSAAPRWAPTPGGLPHQGPRGRAPATPLPQLGRPLFAVAPGDRALSLERAPGTGASVAVAPRSGRKRRSGEDQEKAERGEGTSRSPRGVLRDRGQLEPGTLERDPDKATRFRLEELKLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLFDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEAVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSQYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNVMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCVLPYCSLHLHLKVSENPYTSGIIASRDTAPSIIVASGNIGSELSDSDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEPCVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYHNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSIAFKFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDVSRVIKKALVEATGVPGQHILVAVLPGLPTAAELFVLPHQDPTGENKRPAEDLEQISELMIHKLNQNSVHFELKPGVQVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGINVYAQMQNEKEQEMVSRVSHPESRPYVPQTELRRPGQLIDEKVESQLIGSISIVAENQSTKEIPTYVNV", "length": 1198, "header": "tr|A0A3Q1MSI9-1|A0A3Q1LPL1_BOVIN Computationally mapped isoform of VPS10 domain-containing receptor SorCS1 OS=Bos taurus OX=9913 GN=SORCS1 PE=3 SV=2 CANONICAL=A0A3Q1LPL1-1" }, "locus": { "chromosome": "26", "start_pos": 28129359, "end_pos": 27556250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076462.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076462.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057475.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057475.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:537536", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537536", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPL1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "post-Golgi vesicle-mediated transport", "id": "GO:0006892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006892", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPL1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 816, "end_pos": 818, "annotation": "n_glycosylation_sequon" }, { "start_pos": 847, "end_pos": 849, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 929, "end_pos": 931, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LPL1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1168, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LPL1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPL1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LPL1", "database": "UniProtKB", "url": 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"tr|F1N1N9-1|A0A3Q1LPN8_BOVIN Computationally mapped isoform of HECT and RLD domain containing E3 ubiquitin protein ligase 5 OS=Bos taurus OX=9913 GN=HERC5 PE=4 SV=3 CANONICAL=A0A3Q1LPN8-1" }, "locus": { "chromosome": "6", "start_pos": 36302108, "end_pos": 36257352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052811.3", "url": "https://www.ensembl.org/id/ENSBTAT00000052811.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052996.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052996.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1169408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169408", "resource": "Reactome", "description": "ISG15 antiviral mechanism" }, { "id": "R-BTA-936440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936440", "resource": "Reactome", "description": "Negative regulators of DDX58/IFIH1 signaling" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-BTA-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" }, { "id": "R-BTA-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LA49-1", "protein_name": "HECT and RLD domain containing E3 ubiquitin protein ligase 5", "gene_name": "HERC5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCCTGGRLAVLERGGAGVEVHQLPAGSDGARKPKCIKLGKKMKIHSMDQGAEHMLILSSDGKPFEYNYSIEHARFQCILQEKIIIQITCGDYHSLALSKGGELFAWGENLHGQLGVGRGIASTPTPQMVEHLYGVPLAQVSAGGAHSVALSMSGNVYSWGGNDFGQLGLGHTDDADFPSRIEALDGQHVEFLACGASHTALLTKGGLVLTFGDGRCGQLGHNSTQNELRPRLVTELVGKRVTQMACGREHTLAYVSDLGKVFAFGSGTEGQLGNGGTHNQLIPRPMKLPSNEELKFESRTSEKELIMIAGGNQSILLWMEKENSYVNLRRKIPTLNEGTVKRWLADVGTKQWQNTKREIREIFSSPACLTGSFLRERITGGRTSVHLDLNTARTALSELARKDCITNTITACLRENLLKALPCHSPHREAVEVFFLLPECPVMHDDNNWESLVVPFAEAVGKMSDPSSGVLEEYWASLGESAFIRLVQMFKRAIVAQLRCWTKSAESNCHIKALLELLKKLHRVNQTKCHLPESIFTVNELTDYLDFHEDAYRRSFWKVSSDTSVDIQYPVIFSHFPFIFNILSKIKLLYADSLLKIQQKKIRAYMPLAGILGQEGSELALPPTLNLLVRRGHLIEDVFSHLSRYENEDLRRELLVSFSGEIGYDFGGVRAEFFHCLFEELTQPEYGLFTYPEDASCMWFPARPKFENKSYFFFGILCGLSLFNCNVANIPFPLALFKKLLDQEPSLEDLKELSPVLGQSLQTLLDYEDDDFGKIFHVHFNMHWDKDSVDLIPHGSDVIVDQSNKREYISKYVDYIFNISVKEVYEEFQRGFYRVCDKEIIEFFHPEELKDVIIGNTDYDWETFEKNARYEHGYDNSHPTIVMFWKALHKLTLEEKKKFLVFLTGTDRIQVRGLKNMKITFCCPENMNEKDPIRAQTCFSVLYLPKYSTMERVEEALQVAISNHRGFG", "length": 968 }, "evidence": [ { "id": "A0A3Q1LPN8", "url": "https://omabrowser.org/oma/group/A0A3Q1LPN8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERRSRRKSRRNGRSTAGKAAATQPAKSPGAQLWLFPSAAGLHRALLRRVEVTRQLCCSPGRLAVLERGGAGVQVHQLLAGSGGARTPKCIKLGKNMKIHSVDQGAEHMLILSSDGKPFEYDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKLESHTSEKELIMIAGGNQSILLWIKKENSYVNLKRTIPTLNEGTVKRWIADVETKRWQSTKREIQEIFSSPACLTGSFLRKRRTTEMMPVYLDLNKARNIFKELTQKDWITNMITTCLKDNLLKRLPFHSPPQEALEIFFLLPECPMMHISNNWESLVVPFAKVVCKMSDQSSLVLEEYWATLQESTFSKLVQMFKTAVICQLDYWDESAEENGNVQALLEMLKKLHRVNQVKCQLPESIFQVDELLHRLNFFVEVCRRYLWKMTVDASENVQCCVIFSHFPFIFNNLSKIKLLHTDTLLKIESKKHKAYLRSAAIEEERESEFALRPTFDLTVRRNHLIEDVLNQLSQFENEDLRKELWVSFSGEIGYDLGGVKKEFFYCLFAEMIQPEYGMFMYPEGASCMWFPVKPKFEKKRYFFFGVLCGLSLFNCNVANLPFPLALFKKLLDQMPSLEDLKELSPDLGKNLQTLLDDEGDNFEEVFYIHFNVHWDRNDTNLIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLFHPEELKDVIVGNTDYDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKITFCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG", "length": 1024 }, "evidence": [ { "id": "A0A3Q1LPN8", "url": "https://omabrowser.org/oma/group/A0A3Q1LPN8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" }, { "name": "regulation of defense response to virus", "id": "GO:0050688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050688", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" }, { "name": "ISG15-protein conjugation", "id": "GO:0032020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" }, { "name": "ISG15 transferase activity", "id": "GO:0042296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042296", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LPN8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1038, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LPN8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPN8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPN8" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 716, "end_pos": 1038, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 888, "end_pos": 890 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LPP5-1", "uniprot_ac": "A0A3Q1LPP5", "uniprot_id": "A0A3Q1LPP5_BOVIN", "mass": { "chemical_mass": 57739.0, "monoisotopic_mass": 57739.0 }, "refseq": {}, "gene_names": [ { "name": "EIF2B4", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ] } ], "protein_names": [ { "name": "Translation initiation factor eIF2B subunit delta", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5/entry#names_and_taxonomy" } ] }, { "name": "eIF2B GDP-GTP exchange factor subunit delta", "type": "synonym", "evidence": [ { "id": "A0A3Q1LPP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RXM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM1#function" }, { "database": "UniProtKB", "id": "ARBA00043898", "url": "https://www.uniprot.org/uniprotkb/ARBA00043898#function" }, { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EIF2B4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5", "locus": { "chromosome": "11", "start_pos": 72297447, "end_pos": 72292939, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019510", "url": "https://www.ensembl.org/id/ENSBTAG00000019510" } ] } } ], "crossref": [ { "id": "A0A3Q1LPP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019510", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019510", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MRDYVIC", "url": "https://omabrowser.org/oma/group/MRDYVIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPP5", "url": "https://www.orthodb.org/?gene=A0A3Q1LPP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10233:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10233:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-72731", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72731", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSQQPAVPSTSPPKPSRSLSSSLCALFSDADSGSGMKAELAPRPGAEGREMTQEEKLQLRKEKKQQKKKRKEEKGTETETGSAVSAAQCQVGPAKHLAGPDSQLGTAKEKVPAGRSKAELRAERRAKQEAERALKQARKGDQGGPPPQACPSTAGETPSGVKRLPEHSQVDDPTLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPSEELSRDLVNKLKPYFSFLTQCRPLSASMYNAIKFLNKEITGVSGSKREEEAKSELRAAIDRYIKEKIVLAAQAISRFAYKKISNGDVILGLPLCPLGMMVDSRPRLEAKHTLRSLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLLCERGEHVALANWQNHSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 529, "header": "tr|A0A3Q1LPP5-1|A0A3Q1LPP5_BOVIN Isoform 1 of Translation initiation factor eIF2B subunit delta OS=Bos taurus OX=9913 GN=EIF2B4 PE=3 SV=2 CANONICAL=A0A3Q1LPP5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5/entry", "sequence": { "sequence": "MPSQQPAVPSTSPPKPSRSLSSSLCALFSDADSGSGMKAELAPRPGAEGREMTQEEKLQLRKEKKQQKKKRKEEKGTETETGSAVSAAQCQVGPAKHLAGPDSQLGTAKEKVPAGRSKAELRAERRAKQEAERALKQARKGDQGGPPPQACPSTAGETPSGVKRLPEHSQVDDPTLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPSEELSRDLVNKLKPYFSFLTQCRPLSASMYNAIKFLNKEITGVSGSKREEEAKSELRAAIDRYIKEKIVLAAQAISRFAYKKISNGDVILGLPLCPLGMMVDSRPRLEAKHTLRSLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLLCERGEHVALANWQNHSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 529, "header": "tr|A0A3Q1LPP5-1|A0A3Q1LPP5_BOVIN Isoform 1 of Translation initiation factor eIF2B subunit delta OS=Bos taurus OX=9913 GN=EIF2B4 PE=3 SV=2 CANONICAL=A0A3Q1LPP5-1" }, "locus": { "chromosome": "11", "start_pos": 72297407, "end_pos": 72293271, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077666.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077666.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058974.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058974.2" } ] } }, { "isoform_ac": "A0AAA9RXM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM1/entry", "sequence": { "sequence": "MATAAVAVREDSGSGMKAELAPRPGAEGREMTQEEKLQLRKEKKQQKKKRKEEKGTETETGSAVSAAQCQVGPAKHLAGPDSQLGTAKEKVPAGRSKAELRAERRAKQEAERALKQARKGDQGGPPPQACPSTAGETPSGVKRLPEHSQVDDPTLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPSEELSRDLVNKLKPYFSFLTQCRPLSASMYNAIKFLNKEITGVSGSKREEEAKSELRAAIDRYIKEKIVLAAQAISRFAYKKISNGDVILVYGCSSLVSHILQEAWAKGRQFRVVVVDSRPRLEAKHTLRSLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLLCERGEHVALANWQNHSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 524, "header": "tr|A0AAA9RXM1-1|A0A3Q1LPP5_BOVIN Computationally mapped isoform of Translation initiation factor eIF2B subunit delta OS=Bos taurus OX=9913 GN=EIF2B4 PE=3 SV=2 CANONICAL=A0A3Q1LPP5-1" }, "locus": { "chromosome": "11", "start_pos": 72297407, "end_pos": 72292952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088533.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088533.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075956.2", "url": "https://www.ensembl.org/id/ENSBTAP00000075956.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T493 is on non-canonical isoform A0AAA9RXM1-1 which maps to canonical isoform site A0A3Q1LPP5-1:498", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-72731", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72731", "resource": "Reactome", "description": "Recycling of eIF2:GDP" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B7A1-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "eif2b4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADSDGRQVDSINHATGEEGKLQDIVKAKSEGKELTKEEKQRLRKEKKQHKKNKKDDNKGPPEKEKEKEKEKASAPPPSKPVTQSPAHKAAAPAPVTASASETPAAAEKPAKTKAELRAERRARQDSERASKQGKKEGGQQSTSSKPKASPNELQPVVKRLPEHVQVDDPAALKKLAKKLERQQKSGQGCGLNITGVQVPLRSDYGYKVSLFSHLHQYSRKNPPTQQISIPATVIHPSIVRLGLQYSQGIIAGSNARSVALLHAFKQVIQDYSTPPNEELSRDLVNKLSPYISFLSQCRPLSASMGNAIKYIKKEISNIPNQCKEEEAKGKLQACIDSYINEKIILASEAISKYAIEKISNGDVILVYGCSSLVNHILCEAFEKQRQFRVIVVDSRPRLEGREALRRLVKKGIRCTYVLISALSYILPEVSKVFLGAHALLANGYVMSRVGTSQIALVAKAYNVPVLVCCETYKFCERVQTDSFVSNELDDPDDLIVTRNGKTHLENWQTVKSLGLLNLVYDVTPPDFVDLVITDLGMIPCTSVPVVLRVKNVDQ", "length": 555 }, "evidence": [ { "id": "A0A3Q1LPP5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPP5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Y022-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "EIF2B4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVTLTFWPLESSTSSTTSSVGICCVSCREKGLAAGIGSPAPSATHSGSGGPSRIIPARQLLPTCWALRRKLLKVSLPPSVGSCRTGMEAEQGEELVGKARGPTSTFTCSAAPQCLHPDRAPCAHGWLWFPCGWGSQGVHLCWSREREGAGDRGAALAALCIAGRRSGNDASYYQSAARNTETECCKLSTAGGRGQRWARVAAGRQPGQCHRGTKQGKRPRAAAPRLPACMYFSSCSLRCSTSAGGPELSREEKLQLRKEKKQQKKKKRNEKGTAAEPPEPGTAADPAQPRVTPHPASPPASANAPNDGEKPPGGKSKAELRAERRAKQEAERAQKQAKKAELGQGAAPAKPRLTPTEAPSVVKRLPEHVQVDDPAAQRKLAKKLERQQVPLRQDYGTKVNLFSHLHQYSRKKPLTQQMSIPSTVIHPAVVRLGLQYSQGIINGSNARCIALLEVFKQLIRDYSTPPNEELSRDLVAKLKPHISFLNQCRPLSVSMGNAIKFLKKEISCLPDTLREEEAKEKLQGTIDNYLREKIVLAAEAISKSAFEKINDNDVILVYGCSSLVNRTLCDAHTQTDRTFRVIVVDSRPRLEGRETLRRLVRHGIHCTYVMINAISYVLPEVSKVLLGAHALLANGSVMSRVGTSQIALVSKAYNVPVLVCCETYKFCERVQTDSFVSNELDDPDDLIVQRKGQAQLGGWAENKSLRLLNLVYDVTPPDLVDLVITDLGMIPCTSVPVVLRVKNVDQQ", "length": 747 }, "evidence": [ { "id": "A0A3Q1LPP5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPP5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7G9K9-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "Eif2b4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPTQQPAAPTSLPKLSRSLSGSLCALFSDAESRSEMKAELSPRPGAAGREMTQEEKLQLRKEKKQQKKKRKEEKGADQDVGSAVSAAQSQVDPTRELPAPGRELGGTAGEKIPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPQACPSTAGEATSGVKRLPEHLQVEGPTLLRRLVRKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCITLLRALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPLSASMCNAIKFLNKEITGMSTSKREEEAKSELREAIDRYVQEKIVLAAQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRRMLRSLVHAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEQVALANWQNHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 545 }, "evidence": [ { "id": "A0A3Q1LPP5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPP5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q61749-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "Eif2b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVAVAVREESRSEMKTELSPRPGAAGRELTQEEKLQLRKEKKQQKKKRKEEKGADQEIGSAVSAAQRQDPIRELPGPGSQLGGTAGEKLPAGRSKAELRAERRAKQEAERALKQARKGEQGGVPPQACPSTAGETTSGVKRVPEHTPADDPTLLRRLLRKPDRQQVPTRKDYGSKVSLFSHLPQYSRQSSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCIALLHALQQVIQDYTTPPSEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFLTKEVTGMSSSKREEEAKSELREALDRYVQEKIVLAAQAISRFASTKISDGDVILVYGCSSLVSRILQEARVEGRRFRVVVVDSRPRLEGRHMLHSLVRAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGDQVALANWQSHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 524 }, "evidence": [ { "id": "A0A3Q1LPP5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPP5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63186-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "Eif2b4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVAVAVREESRSEMKTELSPRPGAAGRELTQEEKLQLRKEKKQQKKKRKEEKGADQEIGSAVSAAQRQDPVRELQGTGSQLGGTTGEKLPAGRSKAELRAERRAKQEAERALKQARKGEQGGPSPQACPSTAGEATSGVKRVPEHTQADDPTLLRRLLRKPDRQQVPTRKDYGSKVSLFSHLPQYSRQSSLTQYMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLHALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFFNKEVTGMSSSKREEEAKSELKEAIDRYVQEKIVLASQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRHMLHCLVRAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGDQVTLANWQNNSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 524 }, "evidence": [ { "id": "A0A3Q1LPP5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPP5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UI10-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "EIF2B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 523 }, "evidence": [ { "id": "A0A3Q1LPP5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPP5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1Q8-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "eIF2Bdelta", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLTSEQVPQTLKSKHKKQRQRNRPRNKRNRLEDSHSTTQETSAIDATSAMPGNAVDPLATEKTRDQIMAEREAKKLAKQAKKQKTAPTPTAATPAVLTTPSAPATKIITEVEQTTITTKLTTTTTTKVQDAVASKTTQPAAVNGKDAEAGEKTREQIKAEREAKKAAKKAGKGGGAKVEGIAQQLADLKVAEKAPVAASAAPSTTEADQEKKKPALSKAERRAIQEAQRAAKAQVQTKKAQHAAKAPPSAAPKGPNRKSVSPTTAATSSSPVKCPASTPNVDCRVKLFNHLVCAKEDSQFINDPLVHPSIARLGVQYAKRTVVGSNARCIAFLHALRQVVHDFETPAKKEFGRSLDAAVKHHVDHLHKCRPLAVSVSNAYKQFKNQLTQLPADVPETESKELLVHFIDTYIENQIGKAAQAISGFLQEKITDGDVLLTFACSSLIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCTYVLINAVGYVMAEATKVLLGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQTDAIVYNELSDPNQLVRGDKCQLSNWAAKGKLLPLNLSYDITPPELVSAVVTEVAILPCTSVPVILRIKPDIGY", "length": 626 }, "evidence": [ { "id": "A0A3Q1LPP5", "url": "https://omabrowser.org/oma/group/A0A3Q1LPP5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cytoplasmic translational initiation", "id": "GO:0002183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002183", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" }, { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" }, { "name": "ovarian follicle development", "id": "GO:0001541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001541", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" }, { "name": "oligodendrocyte development", "id": "GO:0014003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014003", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LPP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 529, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LPP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPP5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 498 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 417, "end_pos": 419 }, { "start_pos": 484, "end_pos": 486 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LPQ8-1", "uniprot_ac": "A0A3Q1LPQ8", "uniprot_id": "A0A3Q1LPQ8_BOVIN", "mass": { "chemical_mass": 105328.0, "monoisotopic_mass": 105328.0 }, "refseq": {}, "gene_names": [ { "name": "ARVCF", "type": "recommended", "evidence": [ { "id": "A0A3Q1LPQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ] } ], "protein_names": [ { "name": "ARVCF delta catenin family member", "type": "synonym", "evidence": [ { "id": "A0A3Q1LPQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARVCF", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8", "locus": { "chromosome": "17", "start_pos": 72915660, "end_pos": 72946265, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001473", "url": "https://www.ensembl.org/id/ENSBTAG00000001473" } ] } } ], "crossref": [ { "id": "A0A3Q1LPQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001473", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517045", "url": "https://www.ncbi.nlm.nih.gov/gene/517045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPQ8", "url": "https://www.orthodb.org/?gene=A0A3Q1LPQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NDV7", "url": "https://www.orthodb.org/?gene=A0A3Q1NDV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BPV1", "url": "https://www.orthodb.org/?gene=E1BPV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QX40", "url": "https://www.orthodb.org/?gene=F6QX40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10372:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NDV7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NDV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPV1", "url": "https://www.uniprot.org/uniprotkb/E1BPV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPV1-1", "url": "https://www.uniprot.org/uniprotkb/E1BPV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QX40", "url": "https://www.uniprot.org/uniprotkb/F6QX40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QX40-1", "url": "https://www.uniprot.org/uniprotkb/F6QX40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPECRHGFGDAGALVMEDCSVRSAATILASVREQEARFELLTRALEQERRHVALQLERAQQPGAGGGQSLPMAWQQLVLQEQSPGSQASLATMPEAPEVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTLRQVPVGPDGLPLLDGGPPLGPFTDGPLDRHFLLRGGGPAATLSRTCLGGGGGFPDEPRDVPGYGSLSRGLGVRPPRGGPPGPGPGDGCFTLPSRREAFPVGPGPEPGPPASRSQPERFQAEPYGLEDDARSLAADEEGAPELEPDYCTAARRRPDCGRGLRSRAYEDVVDDGGELMEERPPFPATAAPLAQPERGSLGSLERVVRRSPSADSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEAVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDADNKAAIRDCGGVPALVRLLRAARDSEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPNSGWEPEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIVRNLSYHVHKEVPGAERYQEAEPGPPGGSGSAQRRSREDAGCFGGKKAKEEWFHQGKRDGEMDQNSDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWVWATYIRAAVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRSAQAPARPGVRLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALGASSQSVREAKAASHVLQTVWSYKELRSALQKDGWSKARFQSAAANARGPKAAPSPGGLDDSTLPLVEKSLDGEKPGGRDMIPMEALGPDGYSTMDRRERRPRGSDPAGETSEKEPLKPDPSRKAPPPGPSRPAVRLVDAVGDARPQPVDSWV", "length": 972, "header": "tr|A0A3Q1LPQ8-1|A0A3Q1LPQ8_BOVIN Isoform 1 of ARVCF delta catenin family member OS=Bos taurus OX=9913 GN=ARVCF PE=3 SV=2 CANONICAL=A0A3Q1LPQ8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8/entry", "sequence": { "sequence": "MPECRHGFGDAGALVMEDCSVRSAATILASVREQEARFELLTRALEQERRHVALQLERAQQPGAGGGQSLPMAWQQLVLQEQSPGSQASLATMPEAPEVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTLRQVPVGPDGLPLLDGGPPLGPFTDGPLDRHFLLRGGGPAATLSRTCLGGGGGFPDEPRDVPGYGSLSRGLGVRPPRGGPPGPGPGDGCFTLPSRREAFPVGPGPEPGPPASRSQPERFQAEPYGLEDDARSLAADEEGAPELEPDYCTAARRRPDCGRGLRSRAYEDVVDDGGELMEERPPFPATAAPLAQPERGSLGSLERVVRRSPSADSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEAVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDADNKAAIRDCGGVPALVRLLRAARDSEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPNSGWEPEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIVRNLSYHVHKEVPGAERYQEAEPGPPGGSGSAQRRSREDAGCFGGKKAKEEWFHQGKRDGEMDQNSDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWVWATYIRAAVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRSAQAPARPGVRLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALGASSQSVREAKAASHVLQTVWSYKELRSALQKDGWSKARFQSAAANARGPKAAPSPGGLDDSTLPLVEKSLDGEKPGGRDMIPMEALGPDGYSTMDRRERRPRGSDPAGETSEKEPLKPDPSRKAPPPGPSRPAVRLVDAVGDARPQPVDSWV", "length": 972, "header": "tr|A0A3Q1LPQ8-1|A0A3Q1LPQ8_BOVIN Isoform 1 of ARVCF delta catenin family member OS=Bos taurus OX=9913 GN=ARVCF PE=3 SV=2 CANONICAL=A0A3Q1LPQ8-1" }, "locus": { "chromosome": "17", "start_pos": 72934182, "end_pos": 72916612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070594.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070594.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062081.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062081.2" } ] } }, { "isoform_ac": "A0A3Q1NDV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDV7/entry", "sequence": { "sequence": "MPAELRQEQSPGSQASLATMPEAPEVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTLRQVPVGPDGLPLLDGGPPLGPFTDGPLDRHFLLRGGGPAATLSRTCLGGGGGFPDEPRDVPGYGSLSRGLGVRPPRGGPPGPGPGDGCFTLPSRREAFPVGPGPEPGPPASRSQPERFQAEPYGLEDDARSLAADEEGAPELEPDYCTAARRRPDCGRGLRSRAYEDVVDDGGELMEERPPFPATAAPLAQPERGSLGSLERVVRRSPSADSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEAVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDADNKAAIRDCGGVPALVRLLRAARDSEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPNSGWEPEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIVRNLSYHVHKEVPGAERYQEAEPGPPGGSGSAQRRSREDAGCFGGKKAKGKRDGEMDQNSDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWVWATYIRAAVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRSAQAPARPGVRLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALGASRPGLLWQRPDPRRLLCVPPPQSAAANARGPKAAPSPGGLDDSTLPLVEKSLDGEKPGGRDMIPMEALGPDGYSTMDRRERRPRGSDPAGETSEKEPLKPDPSRKAPPPGPSRPAVRLVDAVGDARPQPVDSWV", "length": 876, "header": "tr|A0A3Q1NDV7-1|A0A3Q1LPQ8_BOVIN Computationally mapped isoform of ARVCF delta catenin family member OS=Bos taurus OX=9913 GN=ARVCF PE=3 SV=3 CANONICAL=A0A3Q1LPQ8-1" }, "locus": { "chromosome": "17", "start_pos": 72929261, "end_pos": 72916612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082497.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082497.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069715.3", "url": "https://www.ensembl.org/id/ENSBTAP00000069715.3" } ] } }, { "isoform_ac": "E1BPV1-1", "url": "https://www.uniprot.org/uniprotkb/E1BPV1/entry", "sequence": { "sequence": "MEDCSVRSAATILASVREQEARFELLTRALEQERRHVALQLERAQQPGAGGGQSLPMAWQQLVLQEQSPGSQASLATMPEAPEVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTLRQVPVGPDGLPLLDGGPPLGPFTDGPLDRHFLLRGGGPAATLSRTCLGGGGGFPDEPRDVPGYGSLSRGLGVRPPRGGPPGPGPGDGCFTLPSRREAFPVGPGPEPGPPASRSQPERFQAEPYGLEDDARSLAADEEGAPELEPDYCTAARRRPDCGRGLRSRAYEDVVDDGGELMEERPPFPATAAPLAQPERGSLGSLERVVRRSPSADSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEAVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDADNKAAIRDCGGVPALVRLLRAARDSEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPNSGWEPEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIVRNLSYHVHKEVPGAERYQEAEPGPPGGSGSAQRRSREDAGCFGGKKAKGKRDGEMDQNSDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWVWATYIRAAVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRSAQAPARPGVRLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALGASSQSVREAKAASHVLQTVWSYKELRSALQKDGWSKARFQSAAANARGPKAAPSPGGLDDSTLPLVEKSLDGEKPGGRDMIPMEALGPDGYSTMDRRERRPRGSDPAGETSEKEPLKGLGLAVCS", "length": 924, "header": "tr|E1BPV1-1|A0A3Q1LPQ8_BOVIN Computationally mapped isoform of ARVCF delta catenin family member OS=Bos taurus OX=9913 GN=ARVCF PE=3 SV=4 CANONICAL=A0A3Q1LPQ8-1" }, "locus": { "chromosome": "17", "start_pos": 72932354, "end_pos": 72916271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061101.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061101.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053343.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053343.4" } ] } }, { "isoform_ac": "F6QX40-1", "url": "https://www.uniprot.org/uniprotkb/F6QX40/entry", "sequence": { "sequence": "MPAELRQEQSPGSQASLATMPEAPEVLEETVTVEEDPGTPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTLRQVPVGPDGLPLLDGGPPLGPFTDGPLDRHFLLRGGGPAATLSRTCLGGGGGFPDEPRDVPGYGSLSRGLGVRPPRGGPPGPGPGDGCFTLPSRREAFPVGPGPEPGPPASRSQPERFQAEPYGLEDDARSLAADEEGAPELEPDYCTAARRRPDCGRGLRSRAYEDVVDDGGELMEERPPFPATAAPLAQPERGSLGSLERVVRRSPSADSARKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEAVKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDADNKAAIRDCGGVPALVRLLRAARDSEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPNSGWEPEPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIVRNLSYHVHKEVPGAERYQEAEPGPPGGSGSAQRRSREDAGCFGGKKAKGKRDGEMDQNSDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWVWATYIRAAVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRSAQAPARPGVRLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALGASSQSVREAKAASHVLQTVWSYKELRSALQKDGWSKARFQSAAANARGPKAAPSPGGLDDSTLPLVEKSLDGEKPGGRDMIPMEALGPDGYSTMDRRERRPRGSDPAGETSEKEPLKGLGLAVCS", "length": 866, "header": "tr|F6QX40-1|A0A3Q1LPQ8_BOVIN Computationally mapped isoform of ARVCF delta catenin family member OS=Bos taurus OX=9913 GN=ARVCF PE=3 SV=3 CANONICAL=A0A3Q1LPQ8-1" }, "locus": { "chromosome": "17", "start_pos": 72929261, "end_pos": 72916271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001929.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001929.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001929.7", "url": "https://www.ensembl.org/id/ENSBTAP00000001929.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LPQ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 972, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LPQ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LPQ8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3Q1LQ14-1", "uniprot_ac": "A0A3Q1LQ14", "uniprot_id": "A0A3Q1LQ14_BOVIN", "mass": { "chemical_mass": 52883.0, "monoisotopic_mass": 52883.0 }, "refseq": {}, "gene_names": [ { "name": "PELI2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase pellino homolog", "type": "recommended", "evidence": [ { "id": "A0A3Q1LQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A3Q1LQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RX62", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX62#function" }, { "database": "UniProtKB", "id": "PIRNR038886", "url": "https://www.uniprot.org/uniprotkb/PIRNR038886#function" }, { "database": "UniProtKB", "id": "A0A3Q1LQ14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQ14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PELI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14", "locus": { "chromosome": "10", "start_pos": 68728050, "end_pos": 68531276, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005141", "url": "https://www.ensembl.org/id/ENSBTAG00000005141" } ] } } ], "crossref": [ { "id": "A0A3Q1LQ14", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LQ14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005141", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005141", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQ14", "url": "https://www.orthodb.org/?gene=A0A3Q1LQ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12098:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12098:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04710", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04710", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20723", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20723", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LQ14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RX62", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RX62-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMN1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMN1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T747", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T747", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T747-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T747-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYFTDIRYPCFNFCFSFCQSPNSHFVTCRTFCLEGKQAICSRSTSCRSCTAVHRGGAERLRSLLLANDGWGASLLLDDRPNKYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNNDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVETETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLLGEQNCIKLIFQGPVD", "length": 476, "header": "tr|A0A3Q1LQ14-1|A0A3Q1LQ14_BOVIN Isoform 1 of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI2 PE=3 SV=1 CANONICAL=A0A3Q1LQ14-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ14/entry", "sequence": { "sequence": "MYFTDIRYPCFNFCFSFCQSPNSHFVTCRTFCLEGKQAICSRSTSCRSCTAVHRGGAERLRSLLLANDGWGASLLLDDRPNKYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNNDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVETETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLLGEQNCIKLIFQGPVD", "length": 476, "header": "tr|A0A3Q1LQ14-1|A0A3Q1LQ14_BOVIN Isoform 1 of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI2 PE=3 SV=1 CANONICAL=A0A3Q1LQ14-1" }, "locus": { "chromosome": "10", "start_pos": 68727046, "end_pos": 68541505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067567.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067567.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062225.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062225.1" } ] } }, { "isoform_ac": "A0AAA9RX62-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX62/entry", "sequence": { "sequence": "TTEQPRDWPPRAPFAAVPFPGALTPFSGWDCSGGADSAGIAAEAAAAAAAAEQGSMFSPGPEEHCAPNKEPVKYGELVVLGYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNNDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVETETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLLGEQNCIKLIFQGPVD", "length": 475, "header": "tr|A0AAA9RX62-1|A0A3Q1LQ14_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI2 PE=3 SV=1 CANONICAL=A0A3Q1LQ14-1" }, "locus": { "chromosome": "10", "start_pos": 68727046, "end_pos": 68532043, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091220.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091220.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077081.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077081.1" } ] } }, { "isoform_ac": "A0AAA9SMN1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMN1/entry", "sequence": { "sequence": "MLVGYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNNDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVETETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLLGEQNCIKLIFQGPVD", "length": 398, "header": "tr|A0AAA9SMN1-1|A0A3Q1LQ14_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI2 PE=3 SV=1 CANONICAL=A0A3Q1LQ14-1" }, "locus": { "chromosome": "10", "start_pos": 68727046, "end_pos": 68549751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122397.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122397.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087612.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087612.1" } ] } }, { "isoform_ac": "A0AAA9T747-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T747/entry", "sequence": { "sequence": "MGSVTSSRRYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNNDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVETETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLLGEQNCIKLIFQGPVD", "length": 403, "header": "tr|A0AAA9T747-1|A0A3Q1LQ14_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI2 PE=3 SV=1 CANONICAL=A0A3Q1LQ14-1" }, "locus": { "chromosome": "10", "start_pos": 68727046, "end_pos": 68552560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117923.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117923.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092427.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092427.1" } ] } }, { "isoform_ac": "A0AAA9TEP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEP8/entry", "sequence": { "sequence": "MLPYPDSRYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISGSQNNDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVETETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLLGEQNCIKLIFQGPVD", "length": 402, "header": "tr|A0AAA9TEP8-1|A0A3Q1LQ14_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase pellino homolog OS=Bos taurus OX=9913 GN=PELI2 PE=3 SV=1 CANONICAL=A0A3Q1LQ14-1" }, "locus": { "chromosome": "10", "start_pos": 68727046, "end_pos": 68531412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120206.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120206.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095288.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095288.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQ14", "url": 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Involved in different DSB repair mechanisms that are guided by annealing of extensive stretches of complementary bases at break ends, such as microhomology-mediated end-joining (MMEJ), single-strand annealing (SSA) or synthesis-dependent strand annealing (SDSA). Possesses both DNA unwinding and annealing activities. Forms a complex with RAD51, stimulating HELQ DNA helicase activity and ability to unwing DNA. Efficiently unwinds substrates containing 3' overhangs or a D-loop. In contrast, interaction with the replication protein A (RPA/RP-A) complex inhibits DNA unwinding by HELQ but strongly stimulates DNA strand annealing. 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"MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRVPRFNGRLRIRIPASLGVQLMSIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRISSLGLVVVDELHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 1085, "header": "tr|A0A3Q1LQC3-1|A0A3Q1LQC3_BOVIN Isoform 1 of Helicase POLQ-like OS=Bos taurus OX=9913 GN=HELQ PE=3 SV=1 CANONICAL=A0A3Q1LQC3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3/entry", "sequence": { "sequence": "MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRVPRFNGRLRIRIPASLGVQLMSIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRISSLGLVVVDELHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 1085, "header": "tr|A0A3Q1LQC3-1|A0A3Q1LQC3_BOVIN Isoform 1 of Helicase POLQ-like OS=Bos taurus OX=9913 GN=HELQ PE=3 SV=1 CANONICAL=A0A3Q1LQC3-1" }, "locus": { "chromosome": "6", "start_pos": 98225864, "end_pos": 98186252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068508.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068508.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059268.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059268.1" } ] } }, { "isoform_ac": "A0A3Q1MB34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MB34/entry", "sequence": { "sequence": "MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRYPDLLWIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRISSLGLVVVDELHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKYELFIVHAFY", "length": 1078, "header": "tr|A0A3Q1MB34-1|A0A3Q1LQC3_BOVIN Computationally mapped isoform of Helicase POLQ-like OS=Bos taurus OX=9913 GN=HELQ PE=3 SV=1 CANONICAL=A0A3Q1LQC3-1" }, "locus": { "chromosome": "6", "start_pos": 98225864, "end_pos": 98186195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072121.1", "url": "https://www.ensembl.org/id/ENSBTAT00000072121.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065868.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065868.1" } ] } }, { "isoform_ac": "A0AAA9SRK1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRK1/entry", "sequence": { "sequence": "MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRYPDLLWIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRISSLGLVVVDELHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 1069, "header": "tr|A0AAA9SRK1-1|A0A3Q1LQC3_BOVIN Computationally mapped isoform of Helicase POLQ-like OS=Bos taurus OX=9913 GN=HELQ PE=3 SV=1 CANONICAL=A0A3Q1LQC3-1" }, "locus": { "chromosome": "6", "start_pos": 98225864, "end_pos": 98186252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133566.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133566.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087996.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087996.1" } ] } }, { "isoform_ac": "A0AAA9TB99-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB99/entry", "sequence": { "sequence": "WTFSALYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 553, "header": "tr|A0AAA9TB99-1|A0A3Q1LQC3_BOVIN Computationally mapped isoform of Helicase POLQ-like OS=Bos taurus OX=9913 GN=HELQ PE=3 SV=1 CANONICAL=A0A3Q1LQC3-1" }, "locus": { "chromosome": "6", "start_pos": 98213691, "end_pos": 98186252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104649.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104649.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093356.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093356.1" } ] } }, { "isoform_ac": "E1BJU9-1", "url": "https://www.uniprot.org/uniprotkb/E1BJU9/entry", "sequence": { "sequence": "MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRYPDLLWIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKLHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 1002, "header": "tr|E1BJU9-1|A0A3Q1LQC3_BOVIN Computationally mapped isoform of Helicase POLQ-like OS=Bos taurus OX=9913 GN=HELQ PE=3 SV=3 CANONICAL=A0A3Q1LQC3-1" }, "locus": { "chromosome": "6", "start_pos": 98225864, "end_pos": 98186252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024158.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024158.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024158.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024158.6" } ] } }, { "isoform_ac": "G3N0Y9-1", "url": "https://www.uniprot.org/uniprotkb/G3N0Y9/entry", "sequence": { "sequence": "MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRISSLGLVVVDELHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 1063, "header": "tr|G3N0Y9-1|A0A3Q1LQC3_BOVIN Computationally mapped isoform of Helicase POLQ-like OS=Bos taurus OX=9913 GN=HELQ PE=3 SV=2 CANONICAL=A0A3Q1LQC3-1" }, "locus": { "chromosome": "6", "start_pos": 98225864, "end_pos": 98186252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064268.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064268.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055509.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055509.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XG98-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEPALAVRRRSRISSARKRSHPPAQPGATSSPLARKRPSGGGEGTPAEPLCNNDSEEDMFGDYDSFHESDSLLAQVLDAEPQHSQEKGLDVKAAGRFAHGNLQSEMDQSKQGNLHAAGDSSVRKVDEHYGFQMNENDAGDADEDLSDSVFDELPSSQLLYLEKTRELSSRSQRSAGTERMDKWENSSLDKIQCPSSPCPDSGHKNRSTKSSKGSVCDSCKSVSLKDHLKNALTGNAKAQTPKVSKTKQLKEAILSEEISVARETIGSSSFDIGPFYGLPSKVKHLLRQFRGIETLYEWQHDCLTLKSLQQRKNLIYSLPTSGGKTLVAEILILQELLCRQKDVLMILPYVAIVQEKVWGLSSFGIELGFLVEEYAGSKGRFPPIKRRIKKSLYIATIEKGHALVNSLIETDRIDDLGLVVVDELHMIGEGSRGAVLEMTLAKILYASKNTHVVGMSATLNNVGDLQKFLQAEYYTKNFRPVELKEYIKIRDTIYEVDSKAENGFTFSRLLNFKYSSSLEKADPDHIVALVTEVIPKYSCLIFCPTKKNCENVATMVCKYLNKEFRAHREKEKQDLIKNLKDIGNGSICPVLRQTIPFGVAYHHSGLTNDERKSIEEAYSRGVLCLLACTATLAAGVNLPARRVILRAPYVASEFLKKNQYKQMIGRAGRAGIDNAGESILVVQEKDKHLVRDLITSPLENCYSNLLPEITKGMQYLLLSLVGLKIAVTQEEVYSFMCHTLLGVQQQLLLKEKSLSEIVRDELENLIEKGLLKGKIMEKDQNSKSTLTVTLLGKATYKGSIDVSYCNLLYKELRKGLEGLVLESSLHLLYLATPYDMVSNCSPDWMIYLRQFNQLSSAEQKVADMVGVPESFIAKKASGQAIRKNVDSTAVNRLYLSFVLYALLKETNVWSVSEKFNMSRGYVQNLLTSAASFASCILHFCEELEEFWVYKALLTELTKRLTYCVKTELIPLMEVAGVLEARAKQLYNAGYKTLAHLANANPETLVKTIEHLSRRQAKQMVSSAKMLLSEKAEALQEEVEELLKVPTDIP", "length": 1050 }, "evidence": [ { "id": "A0A3Q1LQC3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQC3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PT19-1", "protein_name": "Helicase POLQ-like", "gene_name": "Helq", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESSPRIRRRVSLRKRNRRSLESLGAARAPAELQPAEDTEDEAAAGSRRRKTGSPEPAQENDSEEDMFGDYNSFSENSFLAQVDDLEQKYIQLPDCGSRGTDSGTKDLCSEGLGNSLSVPAVDFTDSETREYIKKQGDLDVPVEPEVGGDLSFDMPSSQILYFESMQNSSKDLGDQSTKGRDGKSSNEELHHSHREQPQPKSDFSDVGGSSEASRRRSIKDCLKSAMTGNARAQTPAFPRSKQLRETLLSEEISVARKAIESPSDDLGPFYSLPSKVRDLYAQLKGIKRLYDWQHTCLTLSSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLLILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKGHSLVNALIETGRMGTLGLVVVDELHMIGEGSRGATLEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSRAVDGMTFSRLLNYKYSDALKKVDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSRDYLNHREEEKGELIKSLRNVGHGKVCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMIGRAGRAGIDTAGESILLLQEKDKQQVLGLINGPLEDCHSHLVEEFTKGIQSLFLSLIGLKIAESLGDIYQFMNGTLFGVQQKTLLREKSLWEVTVGALEHLTEKGLLQKDSHGSPEESRCHFRITKLGQASFKGAIDLTYCDTLYRDLKKGLEGLVLESLLHLVYLTTPYDLAAQSEPDWMVYFRQFSQLSPAEQSVATLLGISESFIGRKASGQAIRKKVDKNAVNRLYLSFVLYSLLKETNVWSVSERFNMPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLTELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYRSVVHLANANPEVLVKTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEAEELLRLPADLPGLGGPGSERAGSHAGDLALR", "length": 1065 }, "evidence": [ { "id": "A0A3Q1LQC3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQC3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q4P2-1", "protein_name": "Helicase POLQ-like", "gene_name": "helq", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYTDNQLHDIVVKRNTSSSRKRSRDGVRSHVTPAKKRSSFTSTTCLADKEQIYTQDMAENEGVELCCSDNEDLFEGYDSIVADSSFLAKLEDVELQTRQCYDQQTPNACADDLSDSMLAEDFRDSSPRALPSSQLEFQKAITMPHKSPSRGAPSSSTPYLMNPGPAVNHADLSVNKPHPKARRSMKDHLKKVLMDNAATASTVSKMVQQKEAVMNEEMSFAMQAMESITSEGDLGPFFGLPSKVKDLIFRLKGIQDLYEWQKTCLSLDSIQQRRNLIYSLPTSGGKTLVAEILIFKELLCRKKDALLILPYISLVQEKVRGLSSFGIELDFLVEEYAGSKGKFPPVKRRNKNSLYITTIEKGHSLVNSLIENDRLDNIGLVVVDELHMLGDGSRGAILEMTLSKILYMSKSTQVIGMSATLGNVKDLQSFLRAENYTNNFRPVELKEYVKIKDSIYEVDPKEEACFTFSRLLNFKYSSGMQKMDPDHIIALATEVIPQQSCLIFCATKKNCENLAGMICKYLNKEFIKHKEAEKAILLGELKSSGNGSLCPVLQKTIPFGLAYHHSGLTSDERKLVEEAYSSGVLCLLTCTSTLAAGINLPARRVILRSPYVAADFLKRSQYKQMVGRAGRAGIDAMGESILILQDKDINTAKKLLCAPMEKCYSNLLHDGGRGLLSLILSLIGLKITTTVEQVKDLMKGTFLGVQEAQVSPEKSLWDLTVESIQTLKQKNLIEVSSDENNQNILQITRLGRATYKGSVDLSYCDVLYRDLSKGLEGLLLNSFLHLVYLVTPYDMVHQCKPDWMIYFRQFTNLSAAEQKMATTVGVPESFVARKAAGQSVRKSVDVVVVNRLYLALVLFSLLKETNLWIVSERFQLTRGFVQTLLSSASAFGSSVLHFTEELEEFWAYKALLSELTRRLTYCVQAELIPLMEVSGVLEHRAKQLYSAGYKTLSHLANADPQTLVQTIENLFKKQAYQIIASAKMLLTEKAEALQEEVDDLLMLPLDLPSL", "length": 1010 }, "evidence": [ { "id": "A0A3Q1LQC3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQC3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RVE2-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDGGSRIRRRVSVRKRNRFSTESVLAAPTAAELKPGDEKEEEEMVAGSRRRKTVDVQPVENIDSEEDMFGDYDSFAENSFLAQVDDLEQKYMQIPEQEEHATDHAPEDLCSESIKHSILSSNTVGDFTGVKTEEHTKNQSGHEDVATEPEADLLYDVPSSQMLFFEHLHSSSNNLGDPSLKERDRGSSSHKTVNEELPVSSIEEPQQIDDSSSKVRTSSDGNRRQSLKDHLKSAMAGNARAHTSVFSRTKQLKETLLSEEINVAKKTIASSSDDLGPFYSLPSKVRDLYAQFRGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRKDALMILPYVAIVQEKIAGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRIGGLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIVGMSATLNNVEDLQAFLRAEYYSSWFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKLDPDHLVALVTEVIPNHSCLVFCPTKKNCENVAEMICKILSKEYLKHREKEKHELLKNLKAISGGSVCPVLKHTIPFGVAYHHSGLTNDERKLLEEAHSAGVLCLLTCTSTLAAGVNLPAQRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILIFQEKDKQQVLELISRPLENCYSRLVQEFTKGIQTLFLSLIGLKIATTLGDIYHFMSGTFFGVQQKILLKEKSLWEITVESLRYLTEKGLLQKDTVLTEKGLLQKDTVQGSEEEFQYSFRITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDMASRCDPDWMVYFRQFSQLSPAEQNVATLVGVSENFIGKKASGQAIKKKVDKTIVNRLYLSFVLYTLLKETSVWRVSEKFNMPRGHIQNLLSGAAAFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVAGVLEGRAKQLYNAGYKSLAHLANADPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPSITASSIEKA", "length": 1076 }, "evidence": [ { "id": "A0A3Q1LQC3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQC3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2VPA6-1", "protein_name": "Helicase POLQ-like", "gene_name": "Helq", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDGCPRIRRRVSVRKRNRGNLENLRASPTPAELQPAEDTEDEAAAGSRRRKTGSPEHAQENDSEEDMFGDYDSFTESSFLAHVDDLEQRYMQLPECGDRDADSGTKDLCSAGLKNNLRVTTVINLTDPETSEHGQKQSHLDVPAEPEPGSDLSFDVPSSQILYFENPQNSPEALGDPCTKKTNGDPQKSSHEELVSSHTEQPEPNNDFSNVRAASESSRRKSLKDHLKSTMAGNARAQTPAFPRSKHLREALLSEEISVAKKAIESPSDDLGPFYSLPSKVRDLYVQLKGIKKLYDWQHTCLTLRSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLMILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKAHSLVNALIETSRLSTLGLVVVDELHMIGEGSRGAILEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSQAADGMTFSRLLSYKYSEALKKMDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSKDYLNHREKEKCEVIKSLRNIGNGKVCPVLKRTVPFGIAYHHSGLTSEERKLLEEAYSTGVLCLLTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMVGRAGRAGIDTAGESILLLQEKDKQQVLELISGPLETCCSHLVEEFTKGIQALFLSLIGLKIAASLGDIYQFMSGTFFGVQQKILLKEKSLWEITVDALEHLTEKGLLQKDSCGDNEGLECHFRITKLGQASFKGAIDLAYCDTLYRDLKKGLEGLVLESLLHLIYLTTPYDLAAQSEPDWMVYFKQFGQLSPTEQNVAALLGVSESFIGKKAAGQAVRKKVDKNVVNRLYLSFVLYSLLKETNVWSVSEKFNLPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYNAGYRSIMHLANANPEVLVKTIDHLSRRQARQIVSSAKMLLHEKAEALQGEAEELLRLPADLPGLGGPSSERAGSHAGDVTLS", "length": 1069 }, "evidence": [ { "id": "A0A3Q1LQC3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQC3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDG4-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVASSTDKA", "length": 1101 }, "evidence": [ { "id": "A0A3Q1LQC3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VSE2-1", "protein_name": "Helicase POLQ-like", "gene_name": "mus301", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MANKHNLCKKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSNAHLEDLLDGRKEELFGTQATTSTNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEIVSAAKIILMKKLDHLEEETENLKDCLKTSDKN", "length": 1051 }, "evidence": [ { "id": "A0A3Q1LQC3", "url": "https://omabrowser.org/oma/group/A0A3Q1LQC3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "double-strand break repair via alternative nonhomologous end joining", "id": "GO:0097681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097681", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "DNA double-strand break processing involved in repair via single-strand annealing", "id": "GO:0010792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010792", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "single-stranded 3'-5' DNA helicase activity", "id": "GO:1990518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990518", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", 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"id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9SPF3", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] } ] }, { "uniprot_ac": "A0AAA9STQ6", "gene_name": "G3BP1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": 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"activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] } ] }, { "uniprot_ac": "Q2T9X2", "gene_name": "CCT4", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q2T9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X2" } ] } ] }, { "uniprot_ac": "Q2TBP1", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2TBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBP1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2TBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBP1" } ] } ] }, { "uniprot_ac": "Q2TBU9", "gene_name": 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"name": "negative regulation of blood pressure", "id": "GO:0045776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045776", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type carboxypeptidase activity", "id": "GO:0004185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004185", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LQC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC4" }, { "id": "PS50042", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50042" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclic nucleotide-binding", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 266, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 60, "end_pos": 62 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"uniprot_ac": "A0A3Q1LQC5", "uniprot_id": "A0A3Q1LQC5_BOVIN", "mass": { "chemical_mass": 66281.0, "monoisotopic_mass": 66281.0 }, "refseq": { "ac": "XP_005226310", "name": "chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226310" }, "gene_names": [ { "name": "CSGALNACT2", "type": "recommended", "evidence": [ { "id": "A0A3Q1LQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5" } ] }, { "name": "CSGALNACT2", "type": "synonym", "evidence": [ { "id": "XP_005226310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226310" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A3Q1LQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "A0A3Q1LQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5/entry#names_and_taxonomy" } ] }, { "name": "chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005226310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226310" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CSGALNACT2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5", "locus": { "chromosome": "28", "start_pos": 13584917, "end_pos": 13519045, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005165", "url": "https://www.ensembl.org/id/ENSBTAG00000005165" } ] } } ], "crossref": [ { "id": "A0A3Q1LQC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LQC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005165", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005165", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509328", "url": "https://www.ncbi.nlm.nih.gov/gene/509328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQC5", "url": "https://www.orthodb.org/?gene=A0A3Q1LQC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M3V1", "url": "https://www.orthodb.org/?gene=A0A3Q1M3V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1B7B3", "url": "https://www.orthodb.org/?gene=E1B7B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12369:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12369:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005226310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23464", "url": "https://www.rhea-db.org/rhea/23464", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3V1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B7B3", "url": "https://www.uniprot.org/uniprotkb/E1B7B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B7B3-1", "url": "https://www.uniprot.org/uniprotkb/E1B7B3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEILILFLLFYNLLQKVLTSKELISLGKSRLTRMPRRGLILQTRTHWLLLGLALLCSLILFLYLLECAPQTDGNASLPGIIGENYGKEYYQALLQEQEEHYQTRATSLKRQIAQLKQELQEMSEKMRSLQERKNVGANGISYQGNKEQAPSDLLEFLHSQIDKAEVSIGAKLPSEYGVIPFESFTLMKVFQLEMGLTRHPEEKPVRKDKRDELVEVIEAGLEVINNPDEDDEQEDEDGPLGEKLIFNENDFVEGYYRTEKDKGTQYELFFKKADLMEYRHVTLFRPFGPLMKVKSEMIDITRSVINIIVPLAGRTEAFAQFMQNFRDVCIHQDKRIHLTVVYFGKEGLSKVKSILESVASESNFHNYTLVSLNEEFNRGRGLNVGARAWDKGEVLMFFCDVDIYFSAEFLNSCRLNAEPGKKVFYPVVFSLYNPAIVYANLDVPPPVEQQLVHKKDSGFWRDFGFGMTCQYQSDFLTIGGFDMEVKGWGGEDVHLYRKYLHSDLIVIRTPVPGLFHLWHEKRCADELTPEQYRMCIQSKAMNEASHSHLGMLVFREEIETHLHKQAYRTNSEAVG", "length": 575, "header": "tr|A0A3Q1LQC5-1|A0A3Q1LQC5_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CSGALNACT2 PE=3 SV=2 CANONICAL=A0A3Q1LQC5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5/entry", "sequence": { "sequence": "MEILILFLLFYNLLQKVLTSKELISLGKSRLTRMPRRGLILQTRTHWLLLGLALLCSLILFLYLLECAPQTDGNASLPGIIGENYGKEYYQALLQEQEEHYQTRATSLKRQIAQLKQELQEMSEKMRSLQERKNVGANGISYQGNKEQAPSDLLEFLHSQIDKAEVSIGAKLPSEYGVIPFESFTLMKVFQLEMGLTRHPEEKPVRKDKRDELVEVIEAGLEVINNPDEDDEQEDEDGPLGEKLIFNENDFVEGYYRTEKDKGTQYELFFKKADLMEYRHVTLFRPFGPLMKVKSEMIDITRSVINIIVPLAGRTEAFAQFMQNFRDVCIHQDKRIHLTVVYFGKEGLSKVKSILESVASESNFHNYTLVSLNEEFNRGRGLNVGARAWDKGEVLMFFCDVDIYFSAEFLNSCRLNAEPGKKVFYPVVFSLYNPAIVYANLDVPPPVEQQLVHKKDSGFWRDFGFGMTCQYQSDFLTIGGFDMEVKGWGGEDVHLYRKYLHSDLIVIRTPVPGLFHLWHEKRCADELTPEQYRMCIQSKAMNEASHSHLGMLVFREEIETHLHKQAYRTNSEAVG", "length": 575, "header": "tr|A0A3Q1LQC5-1|A0A3Q1LQC5_BOVIN Isoform 1 of Hexosyltransferase OS=Bos taurus OX=9913 GN=CSGALNACT2 PE=3 SV=2 CANONICAL=A0A3Q1LQC5-1" }, "locus": { "chromosome": "28", "start_pos": 13582030, "end_pos": 13555145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070881.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070881.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059178.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059178.2" } ] } }, { "isoform_ac": "A0A3Q1M3V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3V1/entry", "sequence": { "sequence": "MEILILFLLFYNLLQKVLTSKELISLGKSRLTRMPRRGLILQTRTHWLLLGLALLCSLILFLYLLECAPQTDGNASLPGIIGENYGKEYYQALLQEQEEHYQTRATSLKRQIAQLKQELQEMSEKMRSLQERKNVGANGISYQGNKEQAPSDLLEFLHSQIDKAEVSIGAKLPSEYGVIPFESFTLMKVFQLEMGLTRHPEEKPVRKDKRDELVEVIEAGLEVINNPDEDDEQEDEDGPLGEKLIFNENDFVEGYYRTEKDKGTQYELFFKKADLMEYRHVTLFRPFGPLMKVKSEMIDITRSVINIIVPLAGRTEAFAQFMQNFSESNFHNYTLVSLNEEFNRGRGLNVGARAWDKGEVLMFFCDVDIYFSAEFLNSCRLNAEPGKKVFYPVVFSLYNPAIVYANLDVPPPVEQQLVHKKDSGFWRDFGFGMTCQYQSDFLTIGGFDMEVKGWGGEDVHLYRKYLHSDLIVIRTPVPGLFHLWHEKRCADELTPEQYRMCIQSKAMNEASHSHLGMLVFREEIETHLHKQAYRTNSEAVG", "length": 541, "header": "tr|A0A3Q1M3V1-1|A0A3Q1M3V1_BOVIN Computationally mapped isoform of Hexosyltransferase OS=Bos taurus OX=9913 GN=CSGALNACT2 PE=3 SV=1 CANONICAL=A0A3Q1LQC5-1" }, "locus": { "chromosome": "28", "start_pos": 13582030, "end_pos": 13555145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070412.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070412.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062887.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062887.1" } ] } }, { "isoform_ac": "E1B7B3-1", "url": "https://www.uniprot.org/uniprotkb/E1B7B3/entry", "sequence": { "sequence": "MEILILFLLFYNLLQKVLTSKELISLGKSRLTRMPRRGLILQTRTHWLLLGLALLCSLILFLYLLECAPQTDGNASLPGIIGENYGKEYYQALLQEQEEHYQTRATSLKRQIAQLKQELQEMSEKMRSLQERKNVGANGISYQGNKEQAPSDLLEFLHSQIDKAEVSIGAKLPSEYGVIPFESFTLMKVFQLEMGLTRHPEEKPVRKDKRDELVEVIEAGLEVINNPDEDDEQEDEDGPLGEKLIFNENDFVEGYYRTEKDKGTQYELFFKKADLMEYRHVTLFRPFGPLMKVKSEMIDITRSVINIIVPLAGRTEAFAQFMQNFRDVCIHQDKRIHLTVVYFGKEGLSKVKSILESVARLAPSTCEVYGCWRLWAHIFSALLSERKELSPSESNFHNYTLVSLNEEFNRGRGLNVGARAWDKGEVLMFFCDVDIYFSAEFLNSCRLNAEPGKKVFYPVVFSLYNPAIVYANLDVPPPVEQQLVHKKDSGFWRDFGFGMTCQYQSDFLTIGGFDMEVKGWGGEDVHLYRKYLHSDLIVIRTPVPGLFHLWHEKRCADELTPEQYRMCIQSKAMNEASHSHLGMLVFREEIETHLHKQAYRTNSEAVG", "length": 607, "header": "tr|E1B7B3-1|E1B7B3_BOVIN Computationally mapped isoform of Hexosyltransferase OS=Bos taurus OX=9913 GN=CSGALNACT2 PE=3 SV=3 CANONICAL=A0A3Q1LQC5-1" }, "locus": { "chromosome": "28", "start_pos": 13582030, "end_pos": 13555145, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006810.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006810.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006810.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006810.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5" } ], "pmid": "" }, { "name": "glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047237", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity", "id": "GO:0047238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047238", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQC5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chondroitin sulfate proteoglycan biosynthetic process", "id": "GO:0050650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050650", "evidence": [ { "database": 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"F6R9E0-1", "url": "https://www.uniprot.org/uniprotkb/F6R9E0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LPTAFITPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRGETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSGYTAQEYGAGTYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK", "length": 729, "header": "tr|A0A3Q1LQN7-1|A0A3Q1LQN7_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX17 PE=1 SV=2 CANONICAL=A0A3Q1LQN7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7/entry", "sequence": { "sequence": "LPTAFITPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRGETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSGYTAQEYGAGTYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK", "length": 729, "header": "tr|A0A3Q1LQN7-1|A0A3Q1LQN7_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX17 PE=1 SV=2 CANONICAL=A0A3Q1LQN7-1" }, "locus": { "chromosome": "5", "start_pos": 110180107, "end_pos": 110164410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083709.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083709.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057301.3", "url": "https://www.ensembl.org/id/ENSBTAP00000057301.3" } ] } }, { "isoform_ac": "F6R9E0-1", "url": "https://www.uniprot.org/uniprotkb/F6R9E0/entry", "sequence": { "sequence": "MRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLGSPALGNQMGLQRSI", "length": 418, "header": "tr|F6R9E0-1|A0A3Q1LQN7_BOVIN Computationally mapped isoform of RNA helicase OS=Bos taurus OX=9913 GN=DDX17 PE=1 SV=1 CANONICAL=A0A3Q1LQN7-1" }, "locus": { "chromosome": "5", "start_pos": 110179870, "end_pos": 110167231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037682.6", "url": "https://www.ensembl.org/id/ENSBTAT00000037682.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037506.5", "url": "https://www.ensembl.org/id/ENSBTAP00000037506.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "epithelial to mesenchymal transition", "id": "GO:0001837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001837", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "miRNA metabolic process", "id": "GO:0010586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010586", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "androgen receptor signaling pathway", "id": "GO:0030521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030521", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "estrogen receptor signaling pathway", "id": "GO:0030520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030520", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" }, { "name": "regulation of skeletal muscle cell differentiation", "id": "GO:2001014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001014", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", 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{ "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] } ] }, { "uniprot_ac": "A0A3Q1MR43", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] } ] }, { "uniprot_ac": "A0AAA9RUK3", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RUK3", "database": 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"A0ABI0P204", "gene_name": "LOC112446470", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": 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{ "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": 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"2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": 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"5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + 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"evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP + n phosphate + unwound RNA.", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] } ] }, { "uniprot_ac": "Q0VCX2", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] } ] }, { "uniprot_ac": "Q0VD48", "gene_name": "VPS4B", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] } ] }, { "uniprot_ac": "Q17R09", "gene_name": "DHX38", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q17R09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R09" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q17R09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R09" } ] } ] }, { "uniprot_ac": "Q1LZ78", "gene_name": "NTPCR", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "Q1LZ78", "database": "UniProtKB", "url": 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{ "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] } ] }, { "uniprot_ac": "Q2NKY8", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] } ] }, { "uniprot_ac": "Q2NKZ1", "gene_name": "CCT7", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] }, { "ec_number": "5.6.1.7", "activity": "ATP + H2O + an unfolded polypeptide = ADP + phosphate + a folded polypeptide.", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] }, { "ec_number": "5.6.1.7", "activity": "", "evidence": [ { "id": "Q2NKZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] } ] }, { "uniprot_ac": "Q2NL08", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] }, { "ec_number": 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"MAPGMPGRGGAALLCLSALLAHASGRSHPASPSPPGPQASPVLPISYRLSHTRLAFFLREARPPPPTVANGSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVSWKVRAFIVHSRVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSIVLYLAPNSSSPSSPSLEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVSWAQGTPLPPWEGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHGALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGLVLDVSALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSARESEDEDEEEERPQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVARMVDSSTLAGLEPGTTPFKVVSPLTESVLGETLLTVTEEKVSITQLQAQVVASLALSLRPSPGSSHTILATAAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDERVATVTQDRAFPLVVAEAEGAGELLRAELTIAESCQKTKRKSVLATTRVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGTAGPRPEAAGPGTASPAVPPTEDFLPLPTGFLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPASNPMETVPACCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQAEDPASSPTSKRKRVKFTTFTTLPSEELAYDSVPAGEEDEEDEEDLGWGCPDVTGTTRPAPPPDLHNYMRRIKEIA", "length": 983, "header": "tr|F1N7F0-1|A0A3Q1LQS0_BOVIN Computationally mapped isoform of Transmembrane protein 132E OS=Bos taurus OX=9913 GN=TMEM132E PE=3 SV=4 CANONICAL=A0A3Q1LQS0-1" }, "locus": { "chromosome": "19", "start_pos": 15523386, "end_pos": 15464267, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003470.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003470.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003470.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003470.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:506723", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506723", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQS0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS0" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQS0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "posterior lateral line neuromast hair cell development", "id": "GO:0035677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035677", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQS0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LQS0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1073, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LQS0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LQS0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS0" }, { "id": "PF15706", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15706" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 C-terminal", "eco_id": "ECO_0000259", "start_pos": 875, "end_pos": 941, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0A3Q1LQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS0" }, { "id": "PF15705", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15705" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 N-terminal", "eco_id": "ECO_0000259", "start_pos": 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"url": "https://www.orthodb.org/?gene=G3N0W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46006:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46006:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3928662", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3928662", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQU1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS92", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS92-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYA8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYA8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKY4", "url": "https://www.uniprot.org/uniprotkb/E1BKY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0W1", "url": "https://www.uniprot.org/uniprotkb/G3N0W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0W1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0W1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPPLVSSVPAAGVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPTAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVITSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSIEAERLKQKEQERKILELEKQKEEAQRRAQERDQQWLERVHQEDEQQRPRKPHEEEKLKREESVKKKDSEEKGKPEMQDKLSRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENIKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTEAASTPTPKVAVCETPAPSSTTPAEPSETPNNWADFSSTWPTSTNEKPETDSWDAWATQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGPSESPASLKRVASPAAKPAVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTDPPKPTAFPTVCQVIGMYDYTAQNDDELAFSKGQVINVLNKEDPDWWKGEVHGQVGLFPSNYVKLTTDTDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEGAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVLCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP", "length": 1721, "header": "tr|A0A3Q1LQU1-1|A0A3Q1LQU1_BOVIN Isoform 1 of Intersectin-1 OS=Bos taurus OX=9913 GN=ITSN1 PE=4 SV=2 CANONICAL=A0A3Q1LQU1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQU1/entry", "sequence": { "sequence": "MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPPLVSSVPAAGVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPTAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVITSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSIEAERLKQKEQERKILELEKQKEEAQRRAQERDQQWLERVHQEDEQQRPRKPHEEEKLKREESVKKKDSEEKGKPEMQDKLSRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENIKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTEAASTPTPKVAVCETPAPSSTTPAEPSETPNNWADFSSTWPTSTNEKPETDSWDAWATQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGPSESPASLKRVASPAAKPAVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTDPPKPTAFPTVCQVIGMYDYTAQNDDELAFSKGQVINVLNKEDPDWWKGEVHGQVGLFPSNYVKLTTDTDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEGAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVLCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP", "length": 1721, "header": "tr|A0A3Q1LQU1-1|A0A3Q1LQU1_BOVIN Isoform 1 of Intersectin-1 OS=Bos taurus OX=9913 GN=ITSN1 PE=4 SV=2 CANONICAL=A0A3Q1LQU1-1" }, "locus": { "chromosome": "1", "start_pos": 1834522, "end_pos": 1665342, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081085.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081085.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057382.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057382.2" } ] } }, { "isoform_ac": "A0AAA9SNW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNW9/entry", "sequence": { "sequence": "MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFAGVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPTAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVITSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSIEAERLKQKEQERKILELEKQKEEAQRRAQERDQQWLERVHQEDEQQRPRKPHEEEKLKREESVKKKDSEEKGKPEMQDKLSRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENIKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTEAASTPTPKVAVCETPAPSSTTPAEPSETPNNWADFSSTWPTSTNEKPETDSWDAWATQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQHGFWSLRKSCK", "length": 878, "header": "tr|A0AAA9SNW9-1|A0A3Q1LQU1_BOVIN Computationally mapped isoform of Intersectin-1 OS=Bos taurus OX=9913 GN=ITSN1 PE=4 SV=1 CANONICAL=A0A3Q1LQU1-1" }, "locus": { "chromosome": "1", "start_pos": 1834522, "end_pos": 1736236, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116431.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116431.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084574.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084574.1" } ] } }, { "isoform_ac": "A0AAA9SS92-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS92/entry", "sequence": { "sequence": "MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPPLVSSVPAAGVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPTAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVITSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSIEAERLKQKEQERKILELEKQKEEAQRRAQERDQQWLERVHQEDEQQRPRKPHEEEKLKREESVKKKDSEEKGKPEMQDKLSRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENIKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTEAASTPTPKVAVCETPAPSSTTPAEPSETPNNWADFSSTWPTSTNEKPETDSWDAWATQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQPHLLLHPSMRLGHTHPRILLLLLEPWQESISRSCPPPGVHSPRSPSYQNPSCPSRPGSNTATSGKQALLPAGSFHPSFLSVPTMNGCNLFLAYFLLPSGRHDCLYLFLLHS", "length": 1015, "header": "tr|A0AAA9SS92-1|A0A3Q1LQU1_BOVIN Computationally mapped isoform of Intersectin-1 OS=Bos taurus OX=9913 GN=ITSN1 PE=4 SV=1 CANONICAL=A0A3Q1LQU1-1" }, "locus": { "chromosome": "1", "start_pos": 1834522, "end_pos": 1738428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100507.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100507.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086978.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086978.1" } ] } }, { "isoform_ac": "A0AAA9TYA8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYA8/entry", "sequence": { "sequence": "MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPPLVSSVPAAGVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPTAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVITSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSIEAERLKQKEQERKILELEKQKEEAQRRAQERDQQWLERVHQEDEQQRPRKPHEEEKLKREESVKKKDSEEKGKPEMQDKLSRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENIKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTEAASTPTPKVAVCETPAPSSTTPAEPSETPNNWADFSSTWPTSTNEKPETDSWDAWATQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGPSESPASLKRVASPAAKPAVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTDPPKPTAFPTVCQVIGMYDYTAQNDDELAFSKGQVINVLNKEDPDWWKGEVHGQVGLFPSNYVKLTTDTDPSQQ", "length": 1220, "header": "tr|A0AAA9TYA8-1|A0A3Q1LQU1_BOVIN Computationally mapped isoform of Intersectin-1 OS=Bos taurus OX=9913 GN=ITSN1 PE=4 SV=1 CANONICAL=A0A3Q1LQU1-1" }, "locus": { "chromosome": "1", "start_pos": 1834522, "end_pos": 1719857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103977.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103977.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103620.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103620.1" } ] } }, { "isoform_ac": "E1BKY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BKY4/entry", "sequence": { "sequence": "MAQFPTPFGGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPPLVSSVPAAGVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPTAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVITSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSIEAERLKQKEQERKILELEKQKEEAQRRAQERDQQWLERVHQEDEQQRPRKPHEEEKLKREESVKKKDSEEKGKPEMQDKLSRLFHQHQEPAKPAVQAPWSTAEKGPLTISAQENIKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTEAASTPTPKVAVCETPAPSSTTPAEPSETPNNWADFSSTWPTSTNEKPETDSWDAWATQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSMDSGPSESPASLKRVASPAAKPAVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTDPPKPTAFPTVCQVIGMYDYTAQNDDELAFSKGQVINVLNKEDPDWWKGEVHGQVGLFPSNYVKLTTDTDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESELLTEKEGAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVLCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP", "length": 1716, "header": "tr|E1BKY4-1|E1BKY4_BOVIN Computationally mapped isoform of Intersectin-1 OS=Bos taurus OX=9913 GN=ITSN1 PE=4 SV=3 CANONICAL=A0A3Q1LQU1-1" }, "locus": { "chromosome": "1", "start_pos": 1834522, "end_pos": 1665342, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029333.8", "url": "https://www.ensembl.org/id/ENSBTAT00000029333.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029333.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029333.6" } ] } }, { "isoform_ac": "G3N0W1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0W1/entry", "sequence": { "sequence": 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"MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLAFCSWMTHQSCMFLVKAASLSKRRTYAGLALHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVTGTFRMLLLFAVSLCIVLPLSLQRNMMASIQSFSAMALIFYTVFMFVIVLSSFKHGLFGGQWLQRVSYIRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATEGNVLMHFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGMMIPNVETILGLTGATMGSLICFVCPTLIYKKIHKNSLSSQVVLWVGLGILVISTHTTLSVSQETPMDLAKEAEGGRLEEAKGAVKVEAAQLPGQNPIVDVAEDGRDKPKLPNEKDEMEQAQIKGPVNVPPREDAKEKQEAAQLDRPGQGVAVPLGEAHRHEPPVPHDEVIVDEGQDQEGLEKERPSKHMDERALGGKGQMVPPLLDSGRERPRQDQALEAAGGLPKDSQKVPEENGQPAIEPVKEDLGQGDRGVHQGPQAVLSEGQDVPVAGAGARADGALLPGHAVGAMGKPEEKKEPGGKAPLLEEKPGPGAAPQAEPREQRTEEGQGGEHTGSKLEAEIRKMVAEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQDGQEGEDVDVQPELGVAAPRGKEQEVHDAGMAERPPPQPVEVLPGAPGRPAAPPQGHSQRSVEEPEGAAGRAPAAPPGGADPQPWAAPAEPREGRQGAVPEAEGAGVQERLPVLEPARMPGSPEQHGAGDVPGQSRDVFGGGAHEKKKSGKEAAAAGADTQEADVLGVGAAIGAPQVKSQQASRDRAPGGRSGVAAPQAQVVLHQPEHRADPAGGQGGQQGGHMEMRKEAPGREHVPAPWENTAGQEPEQRPDPELGPKPAIPGDQKPDNAKPNRDLKVQAGSDLRRRRRDVAPLAEAGLAPKDGVIISFNSLPEVQVNDLRSALETQLHQAAGGALRVVPGRQIKQLPGALEEP", "length": 1089, "header": "tr|A0A3Q1LQW5-1|A0A3Q1LQW5_BOVIN Isoform 1 of Solute carrier family 38 member 10 OS=Bos taurus OX=9913 GN=SLC38A10 PE=1 SV=1 CANONICAL=A0A3Q1LQW5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW5/entry", "sequence": { "sequence": "MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLAFCSWMTHQSCMFLVKAASLSKRRTYAGLALHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVTGTFRMLLLFAVSLCIVLPLSLQRNMMASIQSFSAMALIFYTVFMFVIVLSSFKHGLFGGQWLQRVSYIRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATEGNVLMHFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGMMIPNVETILGLTGATMGSLICFVCPTLIYKKIHKNSLSSQVVLWVGLGILVISTHTTLSVSQETPMDLAKEAEGGRLEEAKGAVKVEAAQLPGQNPIVDVAEDGRDKPKLPNEKDEMEQAQIKGPVNVPPREDAKEKQEAAQLDRPGQGVAVPLGEAHRHEPPVPHDEVIVDEGQDQEGLEKERPSKHMDERALGGKGQMVPPLLDSGRERPRQDQALEAAGGLPKDSQKVPEENGQPAIEPVKEDLGQGDRGVHQGPQAVLSEGQDVPVAGAGARADGALLPGHAVGAMGKPEEKKEPGGKAPLLEEKPGPGAAPQAEPREQRTEEGQGGEHTGSKLEAEIRKMVAEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQDGQEGEDVDVQPELGVAAPRGKEQEVHDAGMAERPPPQPVEVLPGAPGRPAAPPQGHSQRSVEEPEGAAGRAPAAPPGGADPQPWAAPAEPREGRQGAVPEAEGAGVQERLPVLEPARMPGSPEQHGAGDVPGQSRDVFGGGAHEKKKSGKEAAAAGADTQEADVLGVGAAIGAPQVKSQQASRDRAPGGRSGVAAPQAQVVLHQPEHRADPAGGQGGQQGGHMEMRKEAPGREHVPAPWENTAGQEPEQRPDPELGPKPAIPGDQKPDNAKPNRDLKVQAGSDLRRRRRDVAPLAEAGLAPKDGVIISFNSLPEVQVNDLRSALETQLHQAAGGALRVVPGRQIKQLPGALEEP", "length": 1089, "header": "tr|A0A3Q1LQW5-1|A0A3Q1LQW5_BOVIN Isoform 1 of Solute carrier family 38 member 10 OS=Bos taurus OX=9913 GN=SLC38A10 PE=1 SV=1 CANONICAL=A0A3Q1LQW5-1" }, "locus": { "chromosome": "19", "start_pos": 51477699, "end_pos": 51437463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082794.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082794.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059367.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059367.1" } ] } }, { "isoform_ac": "E1BF27-1", "url": "https://www.uniprot.org/uniprotkb/E1BF27/entry", "sequence": { "sequence": "MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLAFCSWMTHQSCMFLVKAASLSKRRTYAGLALHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVTGTFRMLLLFAVSLCIVLPLSLQRNMMASIQSFSAMALIFYTVFMFVIVLSSFKHGLFGGQWLQRVSYIRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGMMIPNVETILGLTGATMGSLICFVCPTLIYKKIHKNSLSSQVVLWVGLGILVISTHTTLSVSQETPMDLAKEAEGGRLEEAKGAVKVEAAQLPGQNPIVDVAEDGRDKPKLPNEKDEMEQAQIKGPVNVPPREDAKEKQEAAQLDRPGQGVAVPLGEAHRHEPPVPHDEVIVDEGQDQEGLEKERPSKHMDERALGGKGQMVPPLLDSGRERPRQDQALEAAGGLPKDSQKVPEENGQPAIEPVKEDLGQGDRGVHQGPQAVLSEGQDVPVAGAGARADGALLPGHAVGAMGKPEEKKEPGGKAPLLEEKPGPGAAPQAEPREQRTEEGQGGEHTGSKLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQDGQEGEDVDVQPELGVAAPRGKEQEVHDAGMAERPPPQPVEVLPGAPGRPAAPPQGHSQRSVEEPEGAAGRAPAAPPGGADPQPWAAPAEPREGRQGAVPEAEGAGVQERLPVLEPARMPGSPEQHGAGDVPGQSRDVFGGGAHEKKKSGKEAAAAGADTQEADVLGVGAAIGAPQVKSQQASRDRAPGGRSGVAAPQAQVVLHQPEHRADPAGGQGGQQGGHMEMRKEAPGREHVPAPWENTAGQEPEQRPDPELGPKPAIPGDQKPDNAKPNRDLKVQAGSDLRRRRRDVAPLAEAGLAPKDGVIISFNSLPEVQVNDLRSALETQLHQAAGGALRVVPGRQIKQLPGALEEP", "length": 1020, "header": "tr|E1BF27-1|A0A3Q1LQW5_BOVIN Computationally mapped isoform of Solute carrier family 38 member 10 OS=Bos taurus OX=9913 GN=SLC38A10 PE=1 SV=4 CANONICAL=A0A3Q1LQW5-1" }, "locus": { "chromosome": "19", "start_pos": 51477699, "end_pos": 51437463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024319.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024319.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024319.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024319.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509536", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509536", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6Z226-1", "protein_name": "Solute carrier family 38 member 10 isoform X2", "gene_name": "slc38a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTASNWGLIMNVVNSIVGVSVLTMPFCFKQCGIVLGTLLLFFCSWMTHQSCMFLVHSASNTKRRTYAGLAFHAYGKPGKALVELSMIGLMLGTCIAFYVVIAELGSNFFAQLLGLQVTGSFRVVLLFAVSLFIVLPLSLQRNMMSSIQSFSAMALIFYTLFMFTMVLSSLKHGLLTGQWLNKVIFVRWDGVFRCIPICGMAFACQSQVLPTYDSLDEPSVKRMSTIFTSSLNVVTTFYITVGFFGYVSFTDNIAGNVLMNFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQAINTMLFEQQQKDGTFAAGGYMPPLRFKSITLCIVFGTMFVGILIPNVETILGLTGATMGSLICFICPALIYKKIMKNAWTAQLVLWVGLGILLISTATTMSISSNEPAKITPAQDVPAKTENKLPNIIAPELPKVPVQENRVEPDPGEKPDRPPIEVEQPAEKKADEPPQIKVPVDVVEQKKKEEEVQLDRPEAGVAVPEGEAHRHEPPIPHDGVQIDEIKNQEELEDEKKQPAIVEEEKKLPAREEEEFLAEQGAGQAQEVGSDAVKEEEQKEQDDVEKRAVDKANKVENPEDPKQPLGVHKEPENLPEVKQQHGENEADGQKKPEEIEKAPEPQEEKPKEKIVEEHKDEKVPDGKDGGAEKDGDGDKMEVIKKIVAEGQLDHMLLQVIKEQQEQQKRLLDQQEKLLAVIEEQHKEIHHLDQEEKHLPVNDVVPQVKEGEAEPKAPAAGEGASEVENAVPKQQEDIAVAVKPKVAVDAPEQFQQPQGEPVQVPVAVAVPEEPAAKEAQAVAGLPKNSLELVQDQGVEVPKKEDLELKNEGVLPEVGARGVPLRQREPEVDKINPDALAEKEEKVKQKLAQLEAEKERIEKEKLEKERIEKEVQARVEKERKEREKREELAREKELELVRQQKEHLEKERLEAERLKEEREKMEKEIIERAEEKKRLLEHKERVDQLQQVIDARHEKQKKESLEDENLKQEREKMDKEIMERAEKEKVIQEHKERLEQLQQVIDAKKEADALKEGVPPMPKQNGGRDLKENIVPLEEQKQEKRSREDGGLDLKRRRRALDLEGGEGADLDLLQDVGGLFLNPDLKGQLMAETLVHTRQLQQTFQRQVNEE", "length": 1132 }, "evidence": [ { "id": "A0A3Q1LQW5", "url": "https://omabrowser.org/oma/group/A0A3Q1LQW5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PT23-1", "protein_name": "Solute carrier family 38 member 10", "gene_name": "Slc38a10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAASTSKWGLVTNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGLQVTRTFRVFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSFKHGLFSGQWLQRVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTAFYVMVGFFGYVSFTDATTGNVLIHFPSNLVTEMIRVGFVMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLWVGLGILVVSTLTTLSVSEEAPLDLTQGARSGQRGDAEGAMKVEAARLSVQDPVVVMAEDSQEKLKPAEDKEVLEQAQIKGPVDVPGGDTPKEKQEAAQLDRPGQGIAVPMGEAHRHEPPIPHDKVVVDEGQDQEGPEEKKPPPKLPDEGDPAGRGQGAPLLPESEKKQDPERGEEGKRPEQVLAVGEIERPQKIPEANGQPPVQPRKEDSRPGNRDLHPVPQARVSVELNDLVAGEGKESAQKAGGAPWKPMESAVESNIGGKAGLAVQRPEAAEQREKNEAEQPGGDQAGSKLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIRQQRQEGEEDKPKPADMQPEPGAAVLRGQEEEAEHAGAPDEHAGETLEDNPSQPLQPVLGAPRGHPAPSQDKGQHPLEEVKVLAGRDLADLPAGGSDTEPHGASSKLREDQKGAALKVAEAVRKLVPGDLEPVHKPDPAEVPKSPEKQLAKEVARQRQDVFGEGSQERKETGKDAVAPGADTQKEAAQPLVGAEAEDSHSKSRHSEPTKVPASGPAGMGFQAQARFRQEPQVIFDKSQDSHPEVRSEGPRGVGIPAEEQHRGRGAAAMQEEKQRPDPNSGPKLAVPGDQKPENAKPNRDLKVQAGSDLRRRRRDLASPPEQELAPKDGVIISFNSLPNVQVNDLRSALDTQLRQAAGAALQVVHSRQIKQLSGDLEEA", "length": 1099 }, "evidence": [ { "id": "A0A3Q1LQW5", "url": "https://omabrowser.org/oma/group/A0A3Q1LQW5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9HBR0-1", "protein_name": "Solute carrier family 38 member 10", "gene_name": "SLC38A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHGGHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPELGLKRAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGQLAPRDGVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES", "length": 1119 }, "evidence": [ { "id": "A0A3Q1LQW5", "url": "https://omabrowser.org/oma/group/A0A3Q1LQW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW5" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0A3Q1LQW5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1089, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0A3Q1LQW5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0A3Q1LQW5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3Q1LQW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQW5" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 382, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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